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href="https://www.genesisbiotechgroup.com/news/patents/">Patents</a> </li> <li class="current_page_item"> <a href="https://www.genesisbiotechgroup.com/news/publications/">Publications</a> </li> </ul> </div> <div id="sidebar_bot"></div> </div> <div id="main_column" class="indent"> <div class="accordion_wrapper"> <a class="accordionButton">Comparative Biosciences, Inc.</a> <div class="accordionContent"> <p><strong>Selitrennikoff CP, Sylvia C, Sanchez M, Lawrence P, Trosch K, Carenza A, Meschter C.</strong> 2024. Evaluate the safety of a novel photohydrolysis technology used to clean and disinfect indoor air: A murine study. PLoS One. 19(10):e0307031.. <a href="https://pubmed.ncbi.nlm.nih.gov/39383125/" target="_blank" class="tab_link">PMID: 39383125</a></p> </div> <a class="accordionButton">Institute of Metabolic Disorders</a> <div class="accordionContent"> <p><strong>Villasmil, M. L., J. Francisco, C. Gallo-Ebert, M. Donigan, H. Y. Liu, M. Brower, and J. T. Nickels, Jr.</strong> 2016. Ceramide signals for initiation of yeast mating-specific cell cycle arrest. Cell Cycle 15:441-454. <a href="https://pubmed.ncbi.nlm.nih.gov/26726837/" target="_blank" class="tab_link">PMID: 26726837</a></p> <p><strong>Joseph, B. K., H. Y. Liu, J. Francisco, D. Pandya, M. Donigan, C. Gallo-Ebert, C. Giordano, A. Bata, and J. T. Nickels, Jr.</strong> 2015. Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d. J Biol Chem 290:10588-10598. <a href="https://pubmed.ncbi.nlm.nih.gov/25694423/" target="_blank" class="tab_link">PMID: 25694423</a></p> <p><strong>Rice, L.M., Donigan, M., Yang, M., Liu, W., Pandya, D., Joseph, B.K., Sodi, V., Gearhart, T.L., Yip, S.C., Bouchard, M., & Nickels, J.T. Jr.</strong> 2014. Protein phosphatase 2A regulates low-density lipoprotein uptake through regulating SREBP-2 DNA binding. Journal of Biological Chemistry, 2014 Jun 13; 289(24):17268-17279. <a href="https://pubmed.ncbi.nlm.nih.gov/24770487/" target="_blank" class="tab_link">PMID: 24770487</a></p> <p><strong>Gallo-Ebert, C., Donigan, M., Stroke, I.L., Swanson, R.N., Manners, M.T., Francisco, J., Toner, G., Gallagher, D., Huang, C.Y., Gygax, S.E., Webb, M. & Nickels, J.T., Jr.</strong> 2014. Novel antifungal drug discovery based on targeting pathways regulating the fungus-conserved Upc2 transcription factor. Antimicrob Agents Chemother 58, 258-266. <a href="https://pubmed.ncbi.nlm.nih.gov/24145546/" target="_blank" class="tab_link">PMID: 24145546</a></p> <p><strong>McCourt, P., Gallo-Ebert, C., Gonghong, Y., Jiang, Y. & Nickels, J.T., Jr.</strong> 2013. PP2A(Cdc55) regulates G1 cyclin stability. Cell Cycle 12, 1201-1210.. <a href="https://pubmed.ncbi.nlm.nih.gov/23518505/" target="_blank" class="tab_link">PMID: 23518505</a></p> <p><strong>Gallo-Ebert, C., Donigan, M., Liu, H.Y., Pascual, F., Manners, M., Pandya, D., Swanson, R., Gallagher, D., Chen, W., Carman, G.M. & Nickels, J.T., Jr.</strong> 2013. The yeast anaerobic response element AR1b regulates aerobic antifungal drug-dependent sterol gene expression. J Biol Chem 288, 35466-35477.. <a href="https://pubmed.ncbi.nlm.nih.gov/24163365/" target="_blank" class="tab_link">PMID: 24163365</a></p> <p><strong>Yang, M., Liu, W., Pellicane, C., Sahyoun, C., Joseph, B.K., Gallo-Ebert, C., Donigan, M., Pandya, D., Giordano, C., Bata, A. & Nickels, J.T., Jr.</strong> 2013. Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake. J Lipid Res 55, 226-238.. <a href="https://pubmed.ncbi.nlm.nih.gov/24296663/" target="_blank" class="tab_link">PMID: 24296663</a></p> <p><strong>Gallo-Ebert, C., McCourt, P.C., Donigan, M., Villasmil, M.L., Chen, W., Pandya, D., Franco, J., Romano, D., Chadwick, S.G., Gygax, S.E. & Nickels, J.T., Jr.</strong> 2012. Arv1 lipid transporter function is conserved between pathogenic and nonpathogenic fungi. Fungal Genet Biol 49, 101-113.. <a href="https://pubmed.ncbi.nlm.nih.gov/22142782/" target="_blank" class="tab_link">PMID: 22142782</a></p> </div> <a class="accordionButton">Invivotek</a> <div class="accordionContent"> <p><strong>Donthireddy L, Vonteddu P, Murthy T, Kwak T, Eraslan R, Podojil JR, Elhofy A, Boyne MT, Puisis JJ, Veglia F, Singh SS, Dotiwala F, Montaner LJ, Gabrilovich DI.</strong> 2022. ONP-302 Nanoparticles Inhibit Tumor Growth By Altering Tumor-Associated Macrophages And Cancer-Associated Fibroblasts. J Cancer 28;13(6):1933-1944 (2022). <a href="https://pubmed.ncbi.nlm.nih.gov/35399717/" target="_blank" class="tab_link">PMID: 35399717</a></p> <p><strong>Karla K. Frietze, Alyssa M. Brown, Dividutta Das, Raymond G. Franks, Jessie Lee Cunningham, Michael Hayward, Joseph T. Nickels.</strong> 2022. Lipotoxicity reduces Rig-1 expression and activity leading to impaired autophagy and cell death. Autophagy, 2022, VOL. 18, NO. 1, 142–160 https://doi.org/10.1080/15548627.2021.1920818. </p> <p><strong>Gupta, A., Gullapalli, S., Pan, H. Ramos-Ortolaza, D. L., Hayward, M.D., Low, M.J. Pintar, J.E. Devi, L.A. I.</strong> 2021. Gomes Regulation of Opioid Receptors by Their Endogenous Opioid Peptides. Cell Mol Neurobiol 2021 July ; 41(5): 1103–1118. https://doi.org/10.1007%2Fs10571-020-01015-w. </p> <p><strong>Muhua Yang, Christina Gallo-Ebert, Michael Hayward, Weidong Liu, Virginia McDonough and Joseph T. Nickels, Jr.</strong> 2020. Human insulin growth factor 2 mRNA binding protein 2 increases miR-33a/b inhibition of liver ABCA1 expression and alters low-density apolipoprotein levels in mice Mol and Cell Biol. 2020 Aug; 40(16): e00058-20. DIO: https://doi.org/10.1128%2FMCB.00058-20. </p> <p><strong>Gallo-Ebert C, Francisco J, Liu HY, Draper R, Modi K, Hayward MD, Jones BK, Buiakova O, McDonough V, Nickels, JT Jr.</strong> 2018. Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease. J Biol Chem 296(16): 5956-5974 2018. </p> <p><strong>Lisa D Berman-Booty , Rukiye Eraslan, Umesh Hanumegowda, Glenn H Cantor , Denise I Bounous , Evan B Janovitz, Beverly K Jones , Olesia Buiakova, Michael Hayward, Susan Wee.</strong> 2018. Systemic Loss of C-terminal Src Kinase (CSK) Expression Elicits Spontaneous Suppurative Inflammation in Conditional Knockout Mice. Vet Pathol 2018 Mar;55(2):331-340. </p> <p><strong>He S, Gleason J, Fik-Rymarkiewicz E, DiFiglia A, Bharathan M, Morschauser A, Djuretic I, Xu Y, Krakovsky M, Jankovic V, Buensuceso C, Edinger J, Herzberg U, Hofgartner W, Hariri R.</strong> 2017. Human Placenta-Derived Mesenchymal Stromal-Like Cells Enhance Angiogenesis via T Cell-Dependent Reprogramming of Macrophage Differentiation. Stem Cells 35(6): 1603-1613. <a href="https://pubmed.ncbi.nlm.nih.gov/28233380/" target="_blank" class="tab_link">PMID: 28233380</a></p> </div> <a class="accordionButton">Medical Diagnostic Laboratories</a> <div class="accordionContent"> <p><strong>Stemmer, S and Shurshalina, A.</strong> 2014. Colonoscopic tattoo dye spillage mimics endometriosis on laparoscopy. J Minim Invasive Gynecol, 2014 Jul-Aug; 21(4):704-7. <a href="https://pubmed.ncbi.nlm.nih.gov/24473152/" target="_blank" class="tab_link">PMID: 24473152</a></p> <p><strong>Walsh, P., Overmyer, C., Hancock, C., Heffner, J., Walker, N., Nguyen, T., Shanholtzer, L., Caldera, E., Pusavat, J., Mordechai, E., Adelson, M.E. & Iacono, K.T. 2013.</strong> 2013. Is the interpretation of rapid antigen testing for respiratory syncytial virus as simple as positive or negative? Emerg Med J 31, 153-159. <a href="https://pubmed.ncbi.nlm.nih.gov/23964062/" target="_blank" class="tab_link">PMID: 23964062</a></p> <p><strong>Walsh, P., Overmyer, C., Hancock, C., Heffner, J., Walker, N., Nguyen, T., Shanholtzer, L., Pusavat, J., Mordechai, E., Adelson, M.E. & Iacono, K.T.</strong> 2013. Authors' response. Emerg Med J 31, 174. <a href="https://pubmed.ncbi.nlm.nih.gov/24136121/" target="_blank" class="tab_link">PMID: 24136121</a></p> <p><strong>Biggs C, Walsh P, Overmyer CL, Gonzalez D, Feola M, Mordechai E, Adelson ME, and Iacono KT.</strong> 2010. Performance of influenza rapid antigen testing in influenza in emergency department patients. Emerg Med J. 27(1): 5-7. <a href="https://pubmed.ncbi.nlm.nih.gov/20028996/" target="_blank" class="tab_link">PMID: 20028996</a></p> <p><strong>Vermitsky, J-P., Chadwick, S.G., Self, M.J., Mordechai, E., Adelson, M.E., Nickels, J.T. Jr., and Gygax, S.E.</strong> 2009. CgUpc2 is the master regulator of ergosterol biosynthetic genes in Candida glabrata. Antimicrob. Agents Chemother. Manuscript in preparation.. </p> <p><strong>Vermitsky, J.-P., Self, M.J., Chadwick, S.G., Katiyar, S.K., Mordechai, E., Adelson, M.E., Edlind, T.D., and Gygax, S.E.</strong> 2009. cAMP-PKA kinase Tpk3 negatively regulates Candida glabrata Pdr1. Antimicrob. Agents Chemother. Manuscript in preparation.. </p> <p><strong>Prasad, A., Mordechai, E., Adelson, M.E., and Gygax, S.E.</strong> 2009. PBP4 Polymorphisms Generate Penicillin Tolerance in Group B Streptococcus. Nature Medicine. Manuscript in preparation.. </p> <p><strong>Hilbert D, Paulish T, Mordechai E, Adelson ME, Gygax SE, and Trama JP.</strong> 2009. Antimicrobial non-susceptibility of cervico-vaginal and rectal Escherichia coli isolates is associated with phylogeny and plasmid carriage. 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Stress-induced ceramide-activated protein phosphatase can compensate for loss of amphipysin-like activity in Saccharomyces cerevisiae and functions to reinitiate endocytosis. J Biol Chem, 284(18): 11930-11941. <a href="https://pubmed.ncbi.nlm.nih.gov/19254955/" target="_blank" class="tab_link">PMID: 19254955</a></p> <p><strong>Gygax SE, Vermitsky JP, Self MJ, Mordechai E, Adelson ME, Trama JP.</strong> 2008. Antifungal resistance in vaginal Candida clinical isolates. Antimicrob Agents Chemother, manuscript under review. <a href="https://pubmed.ncbi.nlm.nih.gov/18591262/" target="_blank" class="tab_link">PMID: 18591262</a></p> <p><strong>Hilbert DW, Paulish TE, Mordechai E, Adelson ME, and Trama JP.</strong> 2008. O serogroups, phylogeny, and virulence factors of cervicovaginal and rectal Escherichia coli isolates. 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Rapid detection of Atopobium vaginae and association with organisms implicated in bacterial vaginosis. Mol Cell Probes, 22(2):96-102. <a href="https://pubmed.ncbi.nlm.nih.gov/17913456/" target="_blank" class="tab_link">PMID: 17913456</a></p> <p><strong>McCool TL, Hoey JG, Montileone F, Goldenberg HB, Mordechai E, Adelson ME.</strong> 2008. Discovery and analysis of Bartonella henselae antigens for use in clinical serological assays. Diagn Microbiol Infect Dis, 60(1):17-23. <a href="https://pubmed.ncbi.nlm.nih.gov/17889484/" target="_blank" class="tab_link">PMID: 17889484</a></p> <p><strong>Vermitsky JP, Self MJ, Chadwick SG, Trama JP, Mordechai E, Adelson ME.</strong> 2007. A survey of vaginal flora Candida species isolates from women of different age groups by use of species-specific PCR detection. J Clin Microbiol, 46(4):1501-1503. <a href="https://pubmed.ncbi.nlm.nih.gov/18305136/" target="_blank" class="tab_link">PMID: 18305136</a></p> <p><strong>Gygax SE, Schuyler JA, Trama JP, Mordechai E, Adelson ME.</strong> 2007. The detection of erythromycin and clindamycin resistance genes in both Group B Streptococcal clinical isolates and cervicovaginal/rectal swabs. Microb Drug Resist, 13(2):119-123. <a href="https://pubmed.ncbi.nlm.nih.gov/17650964/" target="_blank" class="tab_link">PMID: 17650964</a></p> <p><strong>Trama JP, Pascal KE, Zimmerman JA, Self MJ, Mordechai E, Adelson ME.</strong> 2007. Identification and genotyping of Molluscum Contagiosum virus from genital swab samples by Real-Time PCR and Pyrosequencing. J Clin Virol, 40(4):325-329. <a href="https://pubmed.ncbi.nlm.nih.gov/17997134/" target="_blank" class="tab_link">PMID: 17997134</a></p> <p><strong>Gygax SE, Schuyler JA, Kimmel LE, Trama JP, Mordechai E, Adelson, ME.</strong> 2006. Erythromycin and clindamycin resistance in Group B Streptococcal clinical isolates. Antimicrob Agents Chemother, 50(5):1875-7. <a href="https://pubmed.ncbi.nlm.nih.gov/16641466/" target="_blank" class="tab_link">PMID: 16641466</a></p> <p><strong>Loa CC, Mordechai E, Tilton RC, Adelson ME.</strong> 2006. Production of recombinant Bartonella henselae 17 kDa protein for antibody-capture enzyme-linked immunosorbent assay. Diagn Microbiol Infect Dis, 55(1):1-7 . <a href="https://pubmed.ncbi.nlm.nih.gov/16490335/" target="_blank" class="tab_link">PMID: 16490335</a></p> <p><strong>Meer-Scherrer L, Adelson ME, Mordechai E, Tilton RC.</strong> 2006. Neuroborreliosis associated with Alzheimer’s disease. Curr Microbiol, 52(4):330-2. <a href="https://pubmed.ncbi.nlm.nih.gov/16528463/" target="_blank" class="tab_link">PMID: 16528463</a></p> <p><strong>Trama JP, Adelson ME, Raphaelli I, Mordechai E.</strong> 2005. Detection of Candida species in vaginal samples in a clinical laboratory setting. 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Discovery of N-Substituted 3-Amino-4-(3-boronopropyl)pyrrolidine-3-carboxylic Acids as Highly Potent Third-Generation Inhibitors of Human Arginase I and II. </p> <p><strong>Fedorova, Olga; Jagdmann, G. Erik; Adams, Rebecca L.; Yuan, Lin; Van Zandt, Michael; Pyle, Anna Marie .</strong> 2018. Small molecules that target group II introns are potent antifungal agents, Nature Chemical Biology (2018), 14 (12), 1073-1078. <a href="https://pubmed.ncbi.nlm.nih.gov/30323219/" target="_blank" class="tab_link">PMID: 30323219</a></p> <p><strong>Van Zandt, Michael C.; Savoy, Jennifer L..</strong> 2018. Method of preparing (3r,4s)-3-acetamido-4-allyl-n-(tert-butyl) pyrrolidine-3-carboxamide, WO 2018209290 A1, 60 pp (2018). </p> <p><strong>Dworak, Jessica; Jagdmann, G. Erik; Van Zandt, Michael.</strong> 2018. Total synthesis of protectin DX, a potent proresolving lipid mediator, Abstracts of Papers, 256th ACS National Meeting & Exposition, Boston, MA, United States, August 19-23, 2018 (2018), ORGN-648. </p> <p><strong>Rinis, Natalia; Golden, Jennifer E.; Marceau, Caleb D.; Carette, Jan E.; Van Zandt, Michael C.; Gilmore, Reid; Contessa, Joseph N.</strong> 2018. Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors, Cell Chemical Biology (2018), 25(10), 1231-1241.e4. <a href="https://pubmed.ncbi.nlm.nih.gov/30078634/" target="_blank" class="tab_link">PMID: 30078634</a></p> <p><strong>Sjogren, Eric B.; Li, Jim; Chen, Lijing; Billedeau, Roland J.; Stanton, Timothy F.; Van Zandt, Michael; Whitehouse, Darren; Jagdmann, Gunnar E., Jr.; Petersen, Lene Raunkjaer; Parlati, Francesco; et al.</strong> 2018. Preparation of boron compounds and using compositions and methods for inhibiting arginase activity, WO 2018119440 A1, 220 pp (2018). </p> <p><strong>Sciavolino, Frank C.; Mathias, Gary; Van Zandt, Michael; Jagdmann, G. Erik; Dworak, Jessica.</strong> 2018. Compositions and methods relating to salts of specialized pro-resolving mediators of inflammation, WO 2017210604 A1, 109 pp (2018). </p> <p><strong>Gopinath, Smita; Kim, Myoungjoo V.; Rakib, Tasfia; Wong, Patrick W.; van Zandt, Michael; Barry, Natasha A.; Kaisho, Tsuneyasu; Goodman, Andrew L.; Iwasaki, Akiko.</strong> 2018. Topical application of aminoglycoside antibiotics enhances host resistance to viral infections in a microbiota-independent manner, Nature Microbiology (2018), 3(5), 611-621. <a href="https://pubmed.ncbi.nlm.nih.gov/29632368/" target="_blank" class="tab_link">PMID: 29632368</a></p> <p><strong>Sjogren, Eric B.; Li, Jim; Van Zandt, Michael; Whitehouse, Darren. .</strong> 2017. Compositions and methods for inhibiting arginase activity, WO 2017075363 A1, 54 pp (2017). </p> <p><strong>Hai, Yang; Edwards, Jennifer E.; Van Zandt, Michael C.; Hoffmann, Karl F.; Christianson, David W.</strong> 2014. Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis, Biochemistry (2014), 53(28), 4671-4684. <a href="https://pubmed.ncbi.nlm.nih.gov/25007099/" target="_blank" class="tab_link">PMID: 25007099</a></p> <p><strong>Van Zandt, Michael; Jagdmann, Jr., Gunnar Erik.</strong> 2013. Ring constrained analogs as arginase inhibitors, WO 2013158262, 52 pp (2013). </p> <p><strong>Golebiowski, Adam; Whitehouse, Darren; Beckett, R. Paul; Van Zandt, Michael; Ji, Min Koo; Ryder, Todd R.; Jagdmann, Erik; Andreoli, Monica; Lee, Yung; Sheeler, Ryan; et al.</strong> 2013. Synthesis of quaternary α-amino acid-based arginase inhibitors via the Ugi reaction, Bioorganic & Medicinal Chemistry Letters (2013), 23(17), 4837-4841. <a href="https://pubmed.ncbi.nlm.nih.gov/23886684/" target="_blank" class="tab_link">PMID: 23886684</a></p> <p><strong>Zhang, Mingbao; Jagdmann, G. Erik, Jr.; Van Zandt, Michael; Beckett, Paul; Schroeter, Hagen.</strong> 2013. Enantioselective synthesis of orthogonally protected (2R,3R)-(-)-epicatechin derivatives, key intermediates in the de novo chemical synthesis of (-)-epicatechin glucuronides and sulfates, Tetrahedron Asymmetry (2013), 24(7), 362-373. </p> <p><strong>Van Zandt, Michael C.; Whitehouse, Darren L.; Golebiowski, Adam; Ji, Min Koo; Zhang, Mingbao; Beckett, R. Paul; Jagdmann, G. Erik; Ryder, Todd R.; Sheeler, Ryan; Andreoli, Monica; et al.</strong> 2013. Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl) hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury, Journal of Medicinal Chemistry (2013), 56(6), 2568-2580. <a href="https://pubmed.ncbi.nlm.nih.gov/23472952/" target="_blank" class="tab_link">PMID: 23472952</a></p> <p><strong>Golebiowski, Adam; Paul Beckett, R.; Van Zandt, Michael; Ji, Min Koo; Whitehouse, Darren; Ryder, Todd R.; Jagdmann, Erik; Andreoli, Monica; Mazur, Adam; Padmanilayam, Manyian; et al.</strong> 2013. 2-Substituted-2-amino-6-boronohexanoic acids as arginase inhibitors, Bioorganic & Medicinal Chemistry Letters (2013), 23(7), 2027-2030. <a href="https://pubmed.ncbi.nlm.nih.gov/23453840/" target="_blank" class="tab_link">PMID: 23453840</a></p> <p><strong>Zhang, Mingbao; Jagdmann, G. Erik; Van Zandt, Michael; Sheeler, Ryan; Beckett, Paul; Schroeter, Hagen.</strong> 2013. Chemical Synthesis and Characterization of Epicatechin Glucuronides and Sulfates: Bioanalytical Standards for Epicatechin Metabolite Identification, Journal of Natural Products (2013), 762), 157-169. <a href="https://pubmed.ncbi.nlm.nih.gov/23356946/" target="_blank" class="tab_link">PMID: 23356946</a></p> <p><strong>Van Zandt, Michael C.; Doan, Brian; Sawicki, Diane R.; Sredy, Janet; Podjarny, Alberto D.</strong> 2009. Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo [2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications, Bioorganic & Medicinal Chemistry Letters (2009), 19(7), 2006-2008. </p> <p><strong>Van Zandt, Michael C.; Jones, Michael L.; Gunn, David E.; Geraci, Leo S.; Jones, J. Howard; Sawicki, Diane R.; Sredy, Janet; Jacot, Jorge L.; DiCioccio, A. Thomas; Petrova, Tatiana; et al.</strong> 2005. Discovery of 3-[(4,5,7-Trifluorobenzothiazol-2-yl)methyl]indole- N-acetic Acid (Lidorestat) and Congeners as Highly Potent and Selective Inhibitors of Aldose Reductase for Treatment of Chronic Diabetic Complications, Journal of Medicinal Chemistry (2005), 48(9), 3141-3152. <a href="https://pubmed.ncbi.nlm.nih.gov/15857120/" target="_blank" class="tab_link">PMID: 15857120</a></p> <p><strong>Van Zandt, Michael C.; Sibley, Evelyn O.; McCann, Erin E.; Combs, Kerry J.; Flam, Brenda; Sawicki, Diane R.; Sabetta, Al; Carrington, Anne; Sredy, Janet; Howard, Eduardo; et al.</strong> 2004. Design and synthesis of highly potent and selective (2-arylcarbamoyl-phenoxy)-acetic acid inhibitors of aldose reductase for treatment of chronic diabetic complications, Bioorganic & Medicinal Chemistry Letters (2004), 12(21), 5661-5675. <a href="https://pubmed.ncbi.nlm.nih.gov/15465344/" target="_blank" class="tab_link">PMID: 15465344</a></p> </div> <a class="accordionButton">NexusPharma</a> <div class="accordionContent"> <p><strong>Gabitova-Cornell L, Surumbayeva A, Peri S, Franco-Barraza J, Restifo D, Weitz N, Ogier C, Goldman AR, Hartman TR, Francescone R, Tan Y, Nicolas E, Shah N, Handorf EA, Cai KQ, O'Reilly AM, Sloma I, Chiaverelli R, Moffitt RA, Khazak V, Fang CY, Golemis EA, Cukierman E, Astsaturov I.</strong> 2020. Cholesterol Pathway Inhibition Induces TGF-? Signaling to Promote Basal Differentiation in Pancreatic Cancer. Cancer Cell 38(4):567-583. e11. doi: 10.1016/j.ccell.2020.08.015. 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