Human TGF-beta 3 DuoSet ELISA DY243: R&D Systems

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class="ds_title">Human TGF-beta 3 DuoSet ELISA </h1> <div class="dsSprite_rnd ds_brand_logo ds_rnd_logo"></div> </div> <div class="product_meta"> <span class="category_number">Catalog #: DY243</span> <br/> <span class="citations"> <a href="#product-citations" id="citation_count" class="jump_to" data-tab="3" data-tabname="product-citations"> 38 Citations </a> </span> <span class="reviews review_stars_5"> <a href="#product-reviews" id="product_reviews" class="jump_to" data-tab="6" data-tabname="product-reviews"> 2 Reviews </a> </span> <a href="/reviews/DY243" rel="nofollow"><span class="submit_review"><button class="btn btn-quaternary">Submit a Review</button></span></a> <span class="datasheet_link"> <a href="#product-datasheets">Datasheet / COA / SDS</a> </span> </div>  <div class="product_wrapper row"> <div class="product_ordering_wrapper col-xs-12 col-md-8 col-md-push-4"> <div class="product_ordering"> <form action="/products/human-tgf-beta-3-duoset-elisa_dy243" method="post" id="atc-datasheet-form" accept-charset="UTF-8"><div><div id="atc_datasheet_block">     <table class="add_to_cart"> <thead> <tr> <th class="ds_catalog">Catalog #</th> <th class="ds_availability_column mobile-hide">Availability</th> <th class="ds_size_price_column">Size / Price</th> <th class="ds_quantity_column">Qty</th> </tr> </thead> <tbody> <tr class="et_atc_product" data-sku="DY243"> <td class="dat_catalog_column">DY243</td> <td class="et_atc_results" colspan="2"></td> <td class="ds_quantity ds_quantity_column"><div class="form-item form-item-catnum-dy243 form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-dy243" name="catnum-DY243" value="" size="5" maxlength="3" /></div></td> </tr> </tbody> </table> <div class="additional_products_header">Ancillary Products Available</div> <div class="additional_product_wrapper"><div class="et_atc_product" data-sku="DY008B"><div class="additional_product_label"><a href="/products/duoset-elisa-ancillary-reagent-kit-2_dy008b">DY008B: DuoSet ELISA Ancillary Reagent Kit 2</a></div><div class="et_atc_results"></div><div class="form-item form-item-catnum-dy008b form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-dy008b" name="catnum-DY008B" value="" size="5" maxlength="3" /></div></div></div><div class="additional_product_wrapper"><div class="et_atc_product" data-sku="DY999B"><div class="additional_product_label"><a href="/products/substrate-reagent-pack_dy999b">DY999B: Substrate Reagent Pack</a></div><div class="et_atc_results"></div><div class="form-item form-item-catnum-dy999b form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-dy999b" name="catnum-DY999B" value="" size="5" maxlength="3" /></div></div></div><div class="additional_product_wrapper"><div class="et_atc_product" data-sku="DY999"><div class="additional_product_label"><a href="/products/substrate-reagent-pack_dy999">DY999: Substrate Reagent Pack</a></div><div class="et_atc_results"></div><div class="form-item form-item-catnum-dy999 form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-dy999" name="catnum-DY999" value="" size="5" maxlength="3" /></div></div></div><div class="additional_product_wrapper"><div class="et_atc_product" data-sku="DY010"><div class="additional_product_label"><a href="/products/sample-activation-kit-1_dy010">DY010: Sample Activation Kit 1</a></div><div class="et_atc_results"></div><div class="form-item form-item-catnum-dy010 form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-dy010" name="catnum-DY010" value="" size="5" maxlength="3" /></div></div></div> <div id="promotion-container"><p>Save on RUO reagents! Up to 30% off + FREE shipping. <a href="/promotions#reagents25" target="_blank">See Details</a>.</p> </div> <div class="ds_atc_pre_buttons"></div> <div class="ds_atc_buttons"> <a href="/quote/instruments/ella-automated-immunoassay-system" class="btn btn-secondary atc_request_quote_simple_plex_assay" style="display:none" rel="nofollow">Request a Quote</a> <a href="/services/bulk-quote-request?catnum=DY243&product=Human TGF-beta 3 DuoSet ELISA" class="btn btn-secondary atc_hidden bulk_btn" style="display:none;" rel="nofollow" title="Competitive discounts on products purchased in bulk quantities">Bulk Orders</a> <button class="btn btn-primary atc_hidden atc_btn form-submit icon-before" style="display:none;" title="Enter quantities above and click to add to cart" type="submit" id="edit-add-to-cart" name="add_to_cart_btn" value="Add to Cart"><span class="icon glyphicon glyphicon-plus" aria-hidden="true"></span> Add to Cart</button> </div> <div class="ds_atc_post_buttons"></div> </div> <input type="hidden" name="form_build_id" value="form-OHPwnOE8-iCJ2Ga3Opl0tWXEpQaNVf0w0L9_sWoabGY" /> <input type="hidden" name="form_id" value="atc_datasheet_form" /> </div></form> </div> </div> <div class="product_image_wrapper col-xs-12 col-md-4 col-md-pull-8"> <div class="product_image"> <span class="product_image_label"> </span> <a class="ds-image overview-images" data-toggle="lightbox" data-gallery="overview-images" onClick="event.preventDefault();" data-title="Human TGF-beta 3 ELISA Standard Curve" data-footer="Human TGF-beta 3 ELISA Standard Curve" title="Cat. No. DY243 - Human TGF-beta 3 DuoSet ELISA" href="https://resources.rndsystems.com/images/datasheets/elisa/DATA_TGFbeta_3_DY243_ELISA_1828.jpg"> <img fetchpriority="high" src="https://resources.rndsystems.com/images/datasheets/elisa/DATA_TGFbeta_3_DY243_ELISA_1828.jpg" class="img-fluid" alt="Human TGF-beta 3 ELISA Standard Curve" title="Human TGF-beta 3 ELISA Standard Curve"> </a> <div class="search_image_other_count"> <span class="search_more_images">1 Image</span> </div> </div> </div> <div id="extra_images overview-images" class="hidden"> </div> </div> <div class="product_info_wrapper"> </div> <div id="view-more-target" class="datasheet_section_element"> <a href="/target/tgf-beta-3?category=" class="btn btn-secondary">All TGF-beta 3 ELISAs</a> </div> </div> <div class="tabbed_content" id="rnd_elisabased"> <div id="ds_tabs" class="tab_menu"> <div class="tab tab_1 tab_open" data-tab="1" data-tabname="product-details" id="dsTabs_product-details"> <span>Product Details</span> </div> <div class="tab tab_2" data-tab="2" data-tabname="assay-procedure" id="dsTabs_assay-procedure"> <span>Procedure</span> </div> <div class="tab tab_3" data-tab="3" data-tabname="product-citations" id="dsTabs_product-citations"> <span>Citations (38)</span> </div> <div class="tab tab_4" data-tab="4" data-tabname="faqs" id="dsTabs_faqs"> <span>FAQs</span> </div> <div class="tab tab_5" data-tab="5" data-tabname="supplemental-products" id="dsTabs_supplemental-products"> <span>Supplemental Products</span> </div> <div class="tab tab_6" data-tab="6" data-tabname="product-reviews" id="dsTabs_product-reviews"> <span> Reviews (2) </span> </div> </div> <div class="tab_content tab_1 tab_open" data-tab="1" data-tabname="product-details" id="product-details"> <div class="datasheet_section_element"> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_summary" id="product-anchor-ds_summary">Summary</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_product_features" id="product-anchor-ds_product_features">Product Features</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_kit_content" id="product-anchor-ds_kit_content">Kit Content</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_other_reagents" id="product-anchor-ds_other_reagents">Other Reagents Required</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_data_examples" id="product-anchor-ds_data_examples">Data Examples</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_datasheets" id="product-anchor-ds_datasheets">Product Datasheets</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_preparation_storage" id="product-anchor-ds_preparation_storage">Preparation and Storage</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_background" id="product-anchor-ds_background">Background</a> </div> <div id="ds_summary" class="datasheet_section"> <h2>Human TGF-beta 3 DuoSet ELISA Summary</h2> <div class="ds_table summary_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Assay Type</div> <div class="ds_table_cell summary_table_data">Solid Phase Sandwich ELISA</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Format</div> <div class="ds_table_cell summary_table_data">96-well strip plate</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Sample Volume Required</div> <div class="ds_table_cell summary_table_data">100 µL</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Assay Range</div> <div class="ds_table_cell summary_table_data">31.2 - 2,000 pg/mL</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Sufficient Materials</div> <div class="ds_table_cell summary_table_data">For fifteen 96-well plates*</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Specificity</div> <div class="ds_table_cell summary_table_data">Please see the <a href="//resources.rndsystems.com/pdfs/datasheets/dy243.pdf" class="ds_pdf">product datasheet</a></div> </div> </div> </div> <p class="subtext">* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided. </p> <div id="ds_product_details" class="datasheet_section"> <p>This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant human TGF-beta3. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.</p> <p> </p> </div> </div> <div id="customer_also_purchased_block" class="loader" data-catalogId="DY243"></div> <div id="ds_product_features" class="datasheet_section"> <h2>Product Features</h2> <ul> <li>Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time</li> <li>Development protocols are provided to guide further assay optimization</li> <li>Assay can be customized to your specific needs</li> <li>Economical alternative to complete kits</li> </ul> </div> <div id="ds_kit_content" class="datasheet_section"> <h2>Kit Content</h2> <ul> <li>Capture Antibody</li> <li>Detection Antibody</li> <li>Recombinant Standard</li> <li>Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)</li> </ul> </div> <div id="ds_other_reagents" class="datasheet_section"> <h2>Other Reagents Required</h2> <div class="other_reagent" id="reagents"><p><strong>DuoSet Ancillary Reagent Kit 2 (5 plates): </strong>(Catalog # <a href="/search?keywords=DY008">DY008</a>) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.</p> <p><strong>The components listed above may be purchased separately:</strong></p> <p><strong>PBS:</strong> (Catalog # <a href="/search?keywords=DY006">DY006</a>), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na<sub>2</sub>HPO<sub>4</sub>, 1.5 mM KH<sub>2</sub>PO<sub>4</sub>, pH 7.2 - 7.4, 0.2 µm filtered<br /> <br /> <strong>Wash Buffer:</strong> (Catalog # <a href="/search?keywords=WA126">WA126</a>), or 0.05% Tween<sup>®</sup> 20 in PBS, pH 7.2-7.4</p> <p><strong>Reagent Diluent: </strong>(Catalog # <a href="/search?keywords=DY995">DY995</a>), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered<br /> <br /> <strong>Substrate Solution:</strong> 1:1 mixture of Color Reagent A (H<sub>2</sub>O<sub>2</sub>) and Color Reagent B (Tetramethylbenzidine) (Catalog # <a href="/search?keywords=DY999">DY999</a>)<br /> <br /> <strong>Stop Solution:</strong> 2 N H<sub>2</sub>SO<sub>4</sub> (Catalog # <a href="/search?keywords=DY994">DY994</a>)</p> <p><strong>Microplates</strong>: R&D Systems (Catalog # <a href="/search?keywords=DY990">DY990</a>)<br /> <br /> <strong>Plate Sealers:</strong> ELISA Plate Sealers (Catalog # <a href="/search?keywords=DY992">DY992</a>)</p></div> </div> <div id="ds_scientific_data" class="datasheet_section"> <div id="ds_data_examples"> <h2>Scientific Data</h2> <div id="data_examples"> <div class="row data_ex_row"> <a id="ds_image_0" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> N/A </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-0" data-title="Human TGF-beta 3 ELISA Standard Curve" data-footer="Human TGF-beta 3 ELISA Standard Curve" title="Cat. No. - Human TGF-beta 3 ELISA Standard Curve" href="https://resources.rndsystems.com/images/datasheets/elisa/DATA_TGFbeta_3_DY243_ELISA_1828.jpg"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/elisa/DATA_TGFbeta_3_DY243_ELISA_1828.jpg" class="img-fluid" alt="Human TGF-beta 3 ELISA Standard Curve" title="Human TGF-beta 3 ELISA Standard Curve"> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">Human TGF-beta 3 ELISA Standard Curve</span> </p> </div> </div> </div> </div> </div> <div class="datasheet_section" id="product-datasheets"> <h2 id="ds_datasheets">Product Datasheets</h2> <div class="product_datasheets"> <span class="sds-message hide"> <p class="sds-label">You must select a language.</p> <span class="close_sds_message">x</span> </span> <div class="ds_document"> <a id="cfpdf" href="//resources.rndsystems.com/pdfs/datasheets/dy243.pdf?v=20250216" class="datasheets-link " target="_blank" rel="noreferrer nofollow">Product Datasheet</a> </div> <div class="ds_document"> <div class="ds_pdfData"><a class="datasheets-link" href="https://www.rndsystems.com/cofas/human-tgf-beta-3-duoset-elisa_dy243">COA</a> </div> </div> <div class="ds_document sds_link"> <a class="sds_non_cf datasheets-link non_cf_download_link" target="_blank" rel="noreferrer" data-path="//resources.rndsystems.com/pdfs/msds/dy243.pdf?v=20250216">SDS</a> </div> <div class="ds_document sds_link"> <a class="sds_non_cf datasheets-link non_cf_download_link" target="_blank" rel="noreferrer" data-path="//resources.rndsystems.com/pdfs/msds/dy243.pdf?v=20250216">SDS</a> </div> <div class="ds_document sds_link"> <a class="sds_non_cf datasheets-link non_cf_download_link" target="_blank" rel="noreferrer" data-path="//resources.rndsystems.com/pdfs/msds/dy243.pdf?v=20250216">SDS</a> </div> </div> </div> <div id="ds_preparation_storage" class="datasheet_section"> <h2>Preparation and Storage</h2> <div class="ds_table prep_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell prep_table_name">Shipping</div> <div class="ds_table_cell prep_table_data">The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. </div> </div> <div class="ds_table_row"> <div class="ds_table_cell prep_table_name">Stability & Storage</div> <div class="ds_table_cell prep_table_data">Store the unopened product at 2 - 8 °C. Do not use past expiration date. </div> </div> </div> </div> </div> <div id="ds_background" class="datasheet_section"> <h2>Background: TGF-beta 3</h2> <p><p>Transforming Growth Factor Beta 1, 2, and 3 (TGF-beta 1, TGF-beta 2, and TGF-beta 3) are highly pleiotropic cytokines that virtually all cell types secrete. TGF-beta molecules are proposed to act as cellular switches that regulate processes such as immune function, proliferation, and epithelial-mesenchymal transition. Targeted deletions of these genes in mice show that each TGF-beta isoform has some non-redundant functions: TGF-beta 1 is involved in hematopoiesis and endothelial differentiation; TGF-beta 2 affects development of cardiac, lung, craniofacial, limb, eye, ear, and urogenital systems; and TGF-beta 3 influences palatogenesis and pulmonary development. The full range of <I>in vitro</I> biological activities of TGF-beta 5 has not yet been explored. However, TGF-beta 1, TGF-beta 2, TGF-beta 3, and TGF-beta 5 have been found to be largely interchangeable in an inhibitory bioassay, and it is anticipated that TGF-beta 5 will show a spectrum of activities similar to the other TGF-beta family members. To date, the production of TGF-beta 5 has only been demonstrated in <I>Xenopus</I>.</p> <P> TGF-beta ligands are initially synthesized as precursor proteins that undergo proteolytic cleavage. The mature segments form active ligand dimers via a disulfide-rich core consisting of the characteristic 'cysteine knot'. TGF-beta signaling begins with binding to a complex of the accessory receptor betaglycan (also known as TGF-beta RIII) and a type II serine/threonine kinase receptor termed TGF-beta RII. This receptor then phosphorylates and activates a type I serine/threonine kinase receptor, either ALK-1 or TGF-beta RI (also called ALK-5). The activated type I receptor phosphorylates and activates Smad proteins that regulate transcription. Use of other signaling pathways that are Smad-independent allows for distinct actions observed in response to TGF-beta in different contexts.</P></p> <div class="ds_table background_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Long Name:</div> <div class="ds_table_cell background_table_data">Transforming Growth Factor beta 3</div> </div> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Entrez Gene IDs:</div> <div class="ds_table_cell background_table_data">7043 (Human); 21809 (Mouse); 25717 (Rat)</div> </div> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Alternate Names:</div> <div class="ds_table_cell background_table_data">ARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor, beta 3</div> </div> </div> </div> </div> </div> <div class="tab_content tab_2" data-tab="2" data-tabname="product-assay-procedure" id="product-assay-procedure"> <a id="assay-procedure"></a> <div id="boxes">  <h2>Assay Procedure</h2> <h3><strong>GENERAL ELISA PROTOCOL</strong></h3> <h4><strong><em>Plate Preparation</em></strong></h4> <ol> <li>Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.</li> <li>Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.</li> <li>Block plates by adding 300 μL Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.</li> <li>Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.</li> </ol> <h4><strong><em>Assay Procedure</em></strong></h4> <ol> <li>Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.</li> <li>Repeat the aspiration/wash as in step 2 of Plate Preparation.</li> <li>Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.</li> <li>Repeat the aspiration/wash as in step 2 of Plate Preparation.</li> <li>Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.</li> <li>Repeat the aspiration/wash as in step 2.</li> <li>Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.</li> <li>Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.</li> <li>Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.</li> </ol> <p> </p> </div> </div> <div class="tab_content tab_3" data-tab="3" data-tabname="product-citations" id="citations"> <a id="citations_section"></a> <h2><span class="citations">Citations for Human TGF-beta 3 DuoSet ELISA</h2> <div id="citation"> <a id="dsTabCitations"></a> <p> R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. </p> <p> <strong><span id="maxcitations">38</span> Citations: Showing <span id="showfrom">1</span> - <span id="showto">10</span> </strong> <br/><strong>Filter your results:</strong> </p> <div class="row"> <div class="col-sm-12"> <div class="citations_filters"> <p style="display:inline;"><b>Filter by:</b></p> <div class="select_wrapper filter_select"> <select id="selSpecies" title="Species"> <option value="All">All Species</option> <option class="citation_filterRadio" value="species" data-filter="Bovine"> Bovine </option> <option class="citation_filterRadio" value="species" data-filter="Human"> Human </option> <option class="citation_filterRadio" value="species" data-filter="Mouse"> Mouse </option> <option class="citation_filterRadio" value="species" data-filter="NA"> N/A </option> <option class="citation_filterRadio" value="species" data-filter="Rabbit"> Rabbit </option> <option class="citation_filterRadio" value="species" data-filter="Rat"> Rat </option> </select> </div> <input type="hidden" id="selAntibody" value="All"> <div class="select_wrapper filter_select"> <select id="selSampleType" title="Sample Types"> <option value="All">All Sample Types</option> <option class="citation_filterRadio" value="sampletype" data-filter="BALF"> BALF </option> <option class="citation_filterRadio" value="sampletype" data-filter="Cell Culture Supernates"> Cell Culture Supernates </option> <option class="citation_filterRadio" value="sampletype" data-filter="Cell Lysates"> Cell Lysates </option> <option class="citation_filterRadio" value="sampletype" data-filter="Collagen Scaffold"> Collagen Scaffold </option> <option class="citation_filterRadio" value="sampletype" data-filter="Complex Sample Type"> Complex Sample Type </option> <option class="citation_filterRadio" value="sampletype" data-filter="Peritoneal Fluid"> Peritoneal Fluid </option> <option class="citation_filterRadio" value="sampletype" data-filter="Plasma"> Plasma </option> <option class="citation_filterRadio" value="sampletype" data-filter="Tissue Homogenates"> Tissue Homogenates </option> </select> </div> </div> </div> </div> <div class="row"> <ol id="citations" class="col-xs-12" data-expandall="false" data-max-citations="38" data-max-show="10"> <li class="top-lined" data-species="NA" data-application="" data-sampletype="Complex Sample Type"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/39104774"> Cartilage lacuna-biomimetic hydrogel microspheres endowed with integrated biological signal boost endogenous articular cartilage regeneration </a> </span><br/> Authors: Li, H;Zhao, T;Yuan, Z;Gao, T;Yang, Y;Li, R;Tian, Q;Tang, P;Guo, Q;Zhang, L;<br/> Bioactive materials<br/> Species: N/A<br/> Sample Types: Complex Sample Type<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/38399866"> Topographically and Chemically Enhanced Textile Polycaprolactone Scaffolds for Tendon and Ligament Tissue Engineering </a> </span><br/> Authors: Bauer, B;Emonts, C;Pitts, J;Buhl, EM;Eschweiler, J;Hänsch, R;Betsch, M;Gries, T;Menzel, H;<br/> Polymers<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/38344180"> Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model </a> </span><br/> Authors: Tietel, Z;Melamed, S;Ogen-Shtern, N;Eretz-Kdosha, N;Silberstein, E;Ayzenberg, T;Dag, A;Cohen, G;<br/> Frontiers in pharmacology<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Bovine" data-application="" data-sampletype="Tissue Homogenates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/37808691"> Physiologic Doses of TGF-? Improve the Composition of Engineered Articular Cartilage </a> </span><br/> Authors: Wang, T;Dogru, S;Dai, Z;Kim, SY;Vickers, NA;Albro, MB;<br/> bioRxiv : the preprint server for biology<br/> Species: Bovine<br/> Sample Types: Tissue Homogenates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Complex Sample Type"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/37111788"> Release of TGF-beta3 from Surface-Modified PCL Fiber Mats Triggers a Dose-Dependent Chondrogenic Differentiation of Human Mesenchymal Stromal Cells </a> </span><br/> Authors: L Berten-Sch, Y Roger, H Bunjes, A Hoffmann<br/> Pharmaceutics, 2023-04-21;15(4):.<br/> Species: Human<br/> Sample Types: Complex Sample Type<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/36966336"> Mesenchymal stromal cells promote the drug resistance of gastrointestinal stromal tumors by activating the PI3K-AKT pathway via TGF-beta2 </a> </span><br/> Authors: Y Zhao, Z Weng, X Zhou, Z Xu, B Cao, B Wang, J Li<br/> Journal of Translational Medicine, 2023-03-25;21(1):219.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Mouse" data-application="" data-sampletype="Tissue Homogenates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/36016413"> Effect of IL-10 Deficiency on TGFbeta Expression during Fatal Alphavirus Encephalomyelitis in C57Bl/6 Mice </a> </span><br/> Authors: NM Martin, DE Griffin<br/> Viruses, 2022-08-16;14(8):.<br/> Species: Mouse<br/> Sample Types: Tissue Homogenates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/35454123"> Cytokine Profile and Anti-Inflammatory Activity of a Standardized Conditioned Medium Obtained by Coculture of Monocytes and Mesenchymal Stromal Cells (PRS CK STORM) </a> </span><br/> Authors: JP Lapuente, A Blázquez-M, J Marco-Brua, G Gómez, P Desportes, J Sanz, P Fernández, M García-Gil, F Bermejo, JV San Martín, A Algaba, JC De Gregori, D Lapuente, A De Gregori, B Lapuente, MV Andrés, A Anel<br/> Biomolecules, 2022-03-31;12(4):.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/34481123"> Latent TGFbeta-binding proteins regulate UCP1 expression and function via TGFbeta2 </a> </span><br/> Authors: D Halbgebaue, J Roos, JB Funcke, H Neubauer, BS Hamilton, E Simon, EZ Amri, KM Debatin, M Wabitsch, P Fischer-Po, D Tews<br/> Molecular Metabolism, 2021-09-01;53(0):101336.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/33494271"> Regulation of Fibroblast Activation Protein by Transforming Growth Factor Beta-1 in Glioblastoma Microenvironment </a> </span><br/> Authors: E Krepela, Z Vanickova, P Hrabal, M Zubal, B Chmielova, E Balaziova, P Vymola, I Matrasova, P Busek, A Sedo<br/> International Journal of Molecular Sciences, 2021-01-21;22(3):.<br/> Species: Human<br/> Sample Types: Cell Lysates<br/> </li> <div id="ds_extra_cits"> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/33360897"> Formation of alginate microspheres prepared by optimized microfluidics parameters for high encapsulation of bioactive molecules </a> </span><br/> Authors: LM Caballero, S Duchi, C Onofrillo, CD O'Connell, C Di Bella, SE Moulton<br/> Journal of colloid and interface science, 2020-12-13;587(0):240-251.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/32913927"> A 3D-Bioprinted dual growth factor-releasing intervertebral disc scaffold induces nucleus pulposus and annulus fibrosus reconstruction </a> </span><br/> Authors: B Sun, M Lian, Y Han, X Mo, W Jiang, Z Qiao, K Dai<br/> Bioact Mater, 2020-08-14;6(1):179-190.<br/> Species: Rat<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/31826469"> Promoted chondrogenesis of hMCSs with controlled release of TGF-beta3 via microfluidics synthesized alginate nanogels </a> </span><br/> Authors: Z Mahmoudi, J Mohammadne, S Razavi Baz, A Abouei Meh, M Saidijam, R Dinarvand, M Ebrahimi W, M Soleimani<br/> Carbohydr Polym, 2019-11-07;229(0):115551.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Tissue Homogenates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/31684150"> Transforming Growth Factor Beta 3-Loaded Decellularized Equine Tendon Matrix for Orthopedic Tissue Engineering </a> </span><br/> Authors: SP Roth, W Brehm, C Gro beta, P Scheibe, S Schubert, J Burk<br/> Int J Mol Sci, 2019-11-03;20(21):.<br/> Species: Human<br/> Sample Types: Tissue Homogenates<br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/30991228"> Synergistic effects of recombinant Lentiviral-mediated BMP2 and TGF-beta3 on the osteogenic differentiation of rat bone marrow mesenchymal stem cells in vitro </a> </span><br/> Authors: W He, L Chen, Y Huang, Z Xu, W Xu, N Ding, J Chen<br/> Cytokine, 2019-04-13;120(0):1-8.<br/> Species: Rat<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Collagen Scaffold"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/29448837"> Restoring tracheal defects in a rabbit model with tissue engineered patches based on TGF-?3-encapsulating electrospun poly(l-lactic acid-co-?-caprolactone)/collagen scaffolds </a> </span><br/> Authors: H Jing, B Gao, M Gao, H Yin, X Mo, X Zhang, K Luo, B Feng, W Fu, J Wang, W Zhang, M Yin, Z Zhu, X He, J Zheng<br/> Artif Cells Nanomed Biotechnol, 2018-02-15;0(0):1-11.<br/> Species: Human<br/> Sample Types: Collagen Scaffold<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28819366"> Paracrine Potential of the Human Adipose Tissue-Derived Stem Cells to Modulate Balance between Matrix Metalloproteinases and Their Inhibitors in the Osteoarthritic Cartilage In Vitro </a> </span><br/> Authors: J Denkovskij, E Bagdonas, I Kusleviciu, Z Mackiewicz, A Unguryte, N Porvanecka, S Fleury, A Venalis, C Jorgensen, E Bernotiene<br/> Stem Cells Int, 2017-07-27;2017(0):9542702.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/28194184"> Signal Factors Secreted by 2D and Spheroid Mesenchymal Stem Cells and by Cocultures of Mesenchymal Stem Cells Derived Microvesicles and Retinal Photoreceptor Neurons </a> </span><br/> Authors: L Xie, M Mao, L Zhou, L Zhang, B Jiang<br/> Stem Cells Int, 2017-01-18;2017(0):2730472.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Mouse" data-application="" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/27939132"> Neuronal Protein 3.1 Deficiency Leads to Reduced Cutaneous Scar Collagen Deposition and Tensile Strength due to Impaired Transforming Growth Factor-?1 to -?3 Translation </a> </span><br/> Authors: Tao Cheng<br/> Am. J. Pathol, 2016-12-08;0(0):.<br/> Species: Mouse<br/> Sample Types: Cell Lysates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/27979585"> The differential expression of protease activated receptors contributes to functional differences between dark and fair keratinocytes </a> </span><br/> Authors: Meilang Xue<br/> J. Dermatol. Sci, 2016-12-05;0(0):.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Peritoneal Fluid"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/25207642"> The peritoneum is both a source and target of TGF-beta in women with endometriosis. </a> </span><br/> Authors: Young V, Brown J, Saunders P, Duncan W, Horne A<br/> PLoS ONE, 2014-09-10;9(9):e106773.<br/> Species: Human<br/> Sample Types: Peritoneal Fluid<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/24550481"> Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. </a> </span><br/> Authors: Brunger J, Huynh N, Guenther C, Perez-Pinera P, Moutos F, Sanchez-Adams J, Gersbach C, Guilak F<br/> Proc Natl Acad Sci U S A, 2014-02-18;111(9):E798-806.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Mouse" data-application="" data-sampletype="Tissue Homogenates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/24474796"> Thymocyte apoptosis drives the intrathymic generation of regulatory T cells. </a> </span><br/> Authors: Konkel J, Jin W, Abbatiello B, Grainger J, Chen W<br/> Proc Natl Acad Sci U S A, 2014-01-13;111(4):E465-73.<br/> Species: Mouse<br/> Sample Types: Tissue Homogenates<br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/24162655"> TGF-beta signaling regulates neuronal C1q expression and developmental synaptic refinement. </a> </span><br/> Authors: Bialas A, Stevens B<br/> Nat Neurosci, 2013-10-27;16(12):1773-82.<br/> Species: Rat<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Rabbit" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/23851345"> Regenerating cartilages by engineered ASCs: prolonged TGF-beta3/BMP-6 expression improved articular cartilage formation and restored zonal structure. </a> </span><br/> Authors: Lu C, Yeh T, Yeh C, Fang Y, Sung L, Lin S, Yen T, Chang Y, Hu Y<br/> Mol Ther, 2013-07-15;22(1):186-95.<br/> Species: Rabbit<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/23208491"> Interaction with colon cancer cells hyperactivates TGF-beta signaling in cancer-associated fibroblasts. </a> </span><br/> Authors: Hawinkels L, Paauwe M, Verspaget H, Wiercinska E, van der Zon J, van der Ploeg K, Koelink P, Lindeman J, Mesker W, ten Dijke P, Sier C<br/> Oncogene, 2012-12-03;33(1):97-107.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/18711401"> Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling. </a> </span><br/> Authors: Pen A, Moreno MJ, Durocher Y, Deb-Rinker P, Stanimirovic DB<br/> Oncogene, 2008-08-18;27(54):6834-44.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Tissue Homogenates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/18039789"> Opposite regulation of transforming growth factors-beta2 and -beta3 expression in the human endometrium. </a> </span><br/> Authors: Gaide Chevronnay HP, Cornet PB, Delvaux D, Lemoine P, Courtoy PJ, Henriet P, Marbaix E<br/> Endocrinology, 2007-11-26;149(3):1015-25.<br/> Species: Human<br/> Sample Types: Tissue Homogenates<br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/18023269"> Autologous stem cell regeneration in craniosynostosis. </a> </span><br/> Authors: Moioli EK, Clark PA, Sumner DR, Mao JJ<br/> Bone, 2007-10-17;42(2):332-40.<br/> Species: Rat<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Mouse" data-application="" data-sampletype="BALF"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/17761617"> Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease. </a> </span><br/> Authors: Alcorn JF, Rinaldi LM, Jaffe EF, van Loon M, Bates JH, Janssen-Heininger YM, Irvin CG<br/> Am. J. Respir. Crit. Care Med., 2007-08-29;176(10):974-82.<br/> Species: Mouse<br/> Sample Types: BALF<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/17013806"> Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway. </a> </span><br/> Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ<br/> J. Cell. Physiol., 2007-01-01;210(1):192-200.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/16891311"> Requirement of Smad3 and CREB-1 in mediating transforming growth factor-beta (TGF beta) induction of TGF beta 3 secretion. </a> </span><br/> Authors: Liu G, Ding W, Neiman J, Mulder KM<br/> J. Biol. Chem., 2006-08-04;281(40):29479-90.<br/> Species: Rat<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Tissue Homogenates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/16622033"> Tumor-derived TGFbeta-1 induces dendritic cell apoptosis in the sentinel lymph node. </a> </span><br/> Authors: Ito M, Minamiya Y, Kawai H, Saito S, Saito H, Nakagawa T, Imai K, Hirokawa M, Ogawa J<br/> J. Immunol., 2006-05-01;176(9):5637-43.<br/> Species: Human<br/> Sample Types: Tissue Homogenates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/16574941"> Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. </a> </span><br/> Authors: Neurohr C, Nishimura SL, Sheppard D<br/> Am. J. Respir. Cell Mol. Biol., 2006-03-30;35(2):252-9.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Plasma"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/15223252"> Increased blood plasma concentrations of TGF-beta isoforms after treatment with intravenous immunoglobulins (i.v.IG) in patients with multiple sclerosis. </a> </span><br/> Authors: Reinhold D, Perlov E, Schrecke K, Kekow J, Brune T, Sailer M<br/> J. Neuroimmunol., 2004-07-01;152(1):191-4.<br/> Species: Human<br/> Sample Types: Plasma<br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/15150113"> The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer. </a> </span><br/> Authors: Rendi MH, Suh N, Lamph WW, Krajewski S, Reed JC, Heyman RA, Berchuck A, Liby K, Risingsong R, Royce DB, Williams CR, Sporn MB<br/> Cancer Res., 2004-05-15;64(10):3566-71.<br/> Species: Rat<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/12237307"> Transforming growth factor-beta -Smad signaling pathway cooperates with NF-kappa B to mediate nontypeable Haemophilus influenzae-induced MUC2 mucin transcription. </a> </span><br/> Authors: Jono H, Shuto T, Xu H, Kai H, Lim DJ, Gum JR, Kim YS, Yamaoka S, Feng XH, Li JD<br/> J. Biol. Chem., 2002-09-16;277(47):45547-57.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> <li class="top-lined" data-species="Human" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/12154395"> Progesterone upregulates TGF-b isoforms (b1, b2, and b3) expression in normal human osteoblast-like cells. </a> </span><br/> Authors: Luo XH, Liao EY, Su X<br/> Calcif. Tissue Int., 2002-08-06;71(4):329-34.<br/> Species: Human<br/> Sample Types: Cell Culture Supernates<br/> </li> </div> </ol> </div> <div class="clearfix"><button class="btn btn-quinary ds_extra_cits pull-right toggle_cits_down" id="toggle_cits"></button></div> </div> </div> <div class="tab_content tab_4" data-tab="4" data-tabname="product-faqs" id="product-faqs"> <h2>FAQs</h2> <div class="row"> <div class="col-xs-12"> <p>No product specific FAQs exist for this product, however you may</p> <a class="btn btn-quinary view_all_faqs_btn" href="/resources/faqs/elisas"> View all ELISA FAQs </a> </div> </div> </div> <div class="tab_content tab_5" data-tab="5" data-tabname="product-supplemental" id="supplemental-products"> <div id="supplemental-products-tab-content-placeholder" class="tab-content-placeholder" data-id="supplemental-products" data-catalog_number="dy243" data-language="en"> <div class="et_spinner_small"></div> Loading... </div> </div> <div class="tab_content tab_6" data-tab="6" data-tabname="product-reviews" id="reviews"> <h3>Reviews for Human TGF-beta 3 DuoSet ELISA</h3> <div class="row"> <div class="col-xs-12"> <div class="datasheet_section"> <div class="row"> <div class="col-md-6"> <p> Average Rating: 5 <span class="review_stars_5"></span> (Based on 2 Reviews) </p> <div class="review_rating_progress"> <div class="row"> <div class="col-xs-3"> 5 Star </div> <div class="col-xs-6"> <div class="progress"> <div class="progress-bar progress-bar-warning" role="progressbar" aria-valuenow="100" aria-valuemin="0" aria-valuemax="100" style="width:100%"> </div> </div> </div> <div class="col-xs-3"> 100% </div> </div> <div class="row"> <div class="col-xs-3"> 4 Star </div> <div class="col-xs-6"> <div class="progress"> <div class="progress-bar progress-bar-warning" role="progressbar" aria-valuenow="0" aria-valuemin="0" aria-valuemax="100" style="width:0%"> </div> </div> </div> <div class="col-xs-3"> 0% </div> </div> <div class="row"> <div class="col-xs-3"> 3 Star </div> <div class="col-xs-6"> <div class="progress"> <div class="progress-bar progress-bar-warning" role="progressbar" aria-valuenow="0" aria-valuemin="0" aria-valuemax="100" style="width:0%"> </div> </div> </div> <div class="col-xs-3"> 0% </div> </div> <div class="row"> <div class="col-xs-3"> 2 Star </div> <div class="col-xs-6"> <div class="progress"> <div class="progress-bar progress-bar-warning" role="progressbar" aria-valuenow="0" aria-valuemin="0" aria-valuemax="100" style="width:0%"> </div> </div> </div> <div class="col-xs-3"> 0% </div> </div> <div class="row"> <div class="col-xs-3"> 1 Star </div> <div class="col-xs-6"> <div class="progress"> <div class="progress-bar progress-bar-warning" role="progressbar" aria-valuenow="0" aria-valuemin="0" aria-valuemax="100" style="width:0%"> </div> </div> </div> <div class="col-xs-3"> 0% </div> </div> </div> </div> <div class="col-md-6"> <div class="well"> <h4>Have you used Human TGF-beta 3 DuoSet ELISA?</h4> <h5><strong>Submit a review and receive an Amazon gift card.</strong></h5> <div class="review_reward_txt"> <p>$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image</p> <p>$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image</p> </div> <a class="btn btn-quinary" href="/reviews/DY243"> Submit a Review </a> </div> </div> </div> </div> </div> </div> <div class="row"> <div class="col-md-12"> <div class="reviews_filters"> <p style="display:inline;"><b>Filter by:</b></p> <div class="select_wrapper"> <select class="review_filter_rating"> <option value="all">All Ratings</option> <option value="5">5</option> </select> </div> <div class="select_wrapper"> <select class="review_filter_application"> <option value="all">All Applications</option> </select> </div> </div> </div> </div> <br/> <div class="review_row" data-rating="5" data-species="" data-application=""> <div class="row"> <div class="col-xs-12 col-sm-10"> <div class="review_title review_stars_5">Human TGF-beta 3 DuoSet ELISA</div> <div class="review_date">By <span class="review_reviewer">Anonymous</span> on 04/09/2021 </div> <div class="row"> <div class="review_specifics col-xs-12"> <span class="ds_review_data"> <strong>Sample Tested: </strong> TGF-beta 3 released from synthetic hydrogels </span> </div> </div> <div class="review_how_used"><p>Amazing kit! Very easy to use and clear instructions. The kit provided highly reproducible results over time.</p></div> </div> </div> <hr/> </div> <div class="review_row" data-rating="5" data-species="" data-application=""> <div class="row"> <div class="col-xs-12 col-sm-10"> <div class="review_title review_stars_5">Human TGF-beta 3 DuoSet ELISA</div> <div class="review_date">By <span class="review_reviewer">Anonymous</span> on 04/02/2020 </div> <div class="row"> <div class="review_specifics col-xs-12"> <span class="ds_review_data"> <strong>Sample Tested: </strong> Serum and Plasma </span> </div> </div> <div class="review_how_used"><p>We used this kit for the quantification of TGF b3 in human serum and plasma. Works very well and well-described protocol.</p></div> </div> <div class="col-xs-12 col-sm-2"> <a class="ds-image" data-toggle="lightbox" href="https://www.rndsystems.com/sites/rndsystems.com/files/reviews/review_dy243_51936_0_0.jpg" data-title="Human TGF-beta 3 DuoSet ELISA DY243" data-gallery="Review-images"> <img loading="lazy" class="img-fluid review_image" alt="Human TGF-beta 3 DuoSet ELISA DY243" title="Human TGF-beta 3 DuoSet ELISA DY243" src="https://www.rndsystems.com/sites/rndsystems.com/files/reviews/review_dy243_51936_0_0.jpg"/> </a> </div> </div> <hr/> </div> </div> </div> </div> <div id="sidebar" class="col-xs-12 col-sm-4 col-md-3 col-lg-3 col-xl-3"> <div class="distributor_region"></div> <div class="widget"> <div class="widget_title">Related Products</div> <div class="widget_content" id="related_products_area"> <ul class="ds_details"> <li> <a href="/target/tgf-beta-3"> All Products for TGF-beta 3 </a> </li> <li> <a href="/target/tgf-beta-3?category=Primary%20Antibodies"> 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Human TGF-beta 3 DuoSet ELISA DY243: R&D Systems