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}) })(jQuery); </script> </head> <body class="post-template-default single single-post postid-16973 single-format-standard header-image header-full-width full-width-content genesis-breadcrumbs-hidden"><div class="site-container"><header class="site-header"><div class="wrap"><div class="title-area"><p class="site-title"><a href="https://www.thermofisher.com/" title="Thermo Fisher Scientific">Thermo Fisher Scientific</a></p><p class="site-description">Molecular testing content for clinical lab professionals and clinicians</p></div></div></header> <nav role="navigation" class="top-menu tm" style=""> <ul> <li><a href="#" aria-haspopup="true">Categories<div data-uw-styling-context="true"><b data-uw-styling-context="true"></b></div></a> <ul class="dropdown" aria-label="submenu"> <li><a href=" https://www.thermofisher.com/blog/clinical-conversations/science-and-education/">Science and education</a></li> <li><a href=" https://www.thermofisher.com/blog/clinical-conversations/product-news/">Product news</a></li> <li><a href=" https://www.thermofisher.com/blog/clinical-conversations/case-studies/">Case studies</a></li> <li><a href=" https://www.thermofisher.com/blog/clinical-conversations/perspectives/">Perspectives</a></li> <li><a href=" https://www.thermofisher.com/blog/clinical-conversations/events/">Events</a></li> <li><a href=" https://www.thermofisher.com/blog/clinical-conversations/news/">News</a></li> </ul> </li> </ul> </nav> <div class="site-inner"><div class="content-sidebar-wrap"><main class="content"><article class="post-16973 post type-post status-publish format-standard has-post-thumbnail category-science-and-education tag-clinical-testing tag-content-article tag-covid-19 tag-pcr entry" aria-label="How COVID-19 Prepared the World for Mpox: Insights from AMP 2022"><header class="entry-header"><h1 class="entry-title">How COVID-19 Prepared the World for Mpox: Insights from AMP 2022</h1> <script type="text/javascript"> function cc_toggle(id){ var s = document.getElementById(id); if(isHidden(s)){ s.style.display = 'inline'; } else { s.style.display = 'none'; } } function isHidden(element){ var style = window.getComputedStyle(element); return (style.display === 'none'); } </script> <span class="cc_sidebar"> <span class="cc_color_bar"> <span class="cc_home_icon"> <a href="https://www.thermofisher.com/blog/clinical-conversations/"><img src="https://www.thermofisher.com/blog/clinical-conversations/wp-content/themes/clinical-conversations/images/icon_home.png" alt="Clinical Conversation blog - home icon" /></a> </span> <span class="cc_post_category"> <a class='cc_colorbar_category' href='https://www.thermofisher.com/blog/clinical-conversations/category/science-and-education/'>Science and education</a> </span>  <span id="cc_post_readtime"> 4 mins. </span> <span class="cc_toggle_social"> <a href="javascript:cc_toggle('cc_jetpack_shares');">Sharing ▼</a> </span> <span class="cc_toggle"> <a href="javascript:cc_toggle('cc_metadata');">Details ▼</a> </span> </span> </span> <span id="cc_jetpack_shares"> <ul> <li><a target="_blank" href='https://www.linkedin.com/shareArticle?mini=true&url=https%3A%2F%2Fwww.thermofisher.com%2Fblog%2Fclinical-conversations%2Fhow-covid-19-prepared-world-for-mpox-insights-from-amp-2022%2F&title=How+COVID-19+Prepared+the+World+for+Mpox%3A+Insights+from+AMP+2022'><img src="https://www.thermofisher.com/blog/clinical-conversations//wp-content/themes/clinical-conversations/images/social_icons_linkedin.jpg" alt="Linked In sharing icon" /></a></li> <li><a target="_blank" href='https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.thermofisher.com%2Fblog%2Fclinical-conversations%2Fhow-covid-19-prepared-world-for-mpox-insights-from-amp-2022%2F'><img src="https://www.thermofisher.com/blog/clinical-conversations//wp-content/themes/clinical-conversations/images/social_icons_facebook.jpg" alt="Facebook sharing icon" /></a></li> <li><a target="_blank" href='https://twitter.com/intent/tweet?text=How+COVID-19+Prepared+the+World+for+Mpox%3A+Insights+from+AMP+2022&url=https%3A%2F%2Fwww.thermofisher.com%2Fblog%2Fclinical-conversations%2Fhow-covid-19-prepared-world-for-mpox-insights-from-amp-2022%2F&'><img src="https://www.thermofisher.com/blog/clinical-conversations//wp-content/themes/clinical-conversations/images/social_icons_twitter.jpg" alt="Twitter sharing icon" /></a></li> <li><a href='mailto:?subject=You might be interested in How COVID-19 Prepared the World for Mpox: Insights from AMP 2022 from the Clinical Conversations blog.&body=You might be interested in How COVID-19 Prepared the World for Mpox: Insights from AMP 2022 from the Clinical Conversations blog at https%3A%2F%2Fwww.thermofisher.com%2Fblog%2Fclinical-conversations%2Fhow-covid-19-prepared-world-for-mpox-insights-from-amp-2022%2F'><img src="https://www.thermofisher.com/blog/clinical-conversations/wp-content/themes/clinical-conversations/images/icon_email.png" alt="Email sharing icon" /></a></li> </ul> </span> <span id="cc_metadata"> <span class="cc_dateline"> <span class="post-info-date">  14 Mar 2023 </span> || <span class="post-info-author">   By Clinical Conversations Staff </span> </span> <span class="cc_shares"> <span class="cc_shares_subhead" >Shares: <span class="share_count">0</span> </span> </span> <span class="cc_version"> <span class="cc_version_subhead">Versions of this article</span> Original article. </span> <span class="cc_post_tags"> <span class="cc_post_tags_subhead">Tags</span> <a href='https://www.thermofisher.com/blog/clinical-conversations/tag/clinical-testing/'>Clinical testing</a>, <a href='https://www.thermofisher.com/blog/clinical-conversations/tag/covid-19/'>COVID-19</a>, <a href='https://www.thermofisher.com/blog/clinical-conversations/tag/pcr/'>PCR</a> </span>   </span> <script type="text/javascript"> cc_toggle('cc_metadata'); cc_toggle('cc_jetpack_shares'); </script> </header><div class="entry-content"><p>In May 2022, cases of mpox (formerly referred to as monkeypox) were reported concurrently in both non-endemic and endemic regions for the first time [1]. Countries like the United States and the United Kingdom where mpox was considered rare saw widespread outbreaks, resulting in emergency declarations and vaccination campaigns. Today, more than 81,000 cases have been reported in locations that have not historically reported mpox [2]. Although it remains a threat, cases have decreased since the outbreak’s peak in summer 2022, and the Biden administration ended its mpox public health emergency in late January [3].</p> <p><img decoding="async" class="aligncenter size-full wp-image-16974" src="https://www.thermofisher.com/blog/clinical-conversations/wp-content/uploads/sites/18/2023/03/PG2814-PJT10311-COL024299-MPX-sh2164832913-1200x675-1.jpg" alt="" width="1200" height="675" srcset="https://www.thermofisher.com/blog/clinical-conversations/wp-content/uploads/sites/18/2023/03/PG2814-PJT10311-COL024299-MPX-sh2164832913-1200x675-1.jpg 1200w, https://www.thermofisher.com/blog/clinical-conversations/wp-content/uploads/sites/18/2023/03/PG2814-PJT10311-COL024299-MPX-sh2164832913-1200x675-1-300x169.jpg 300w, https://www.thermofisher.com/blog/clinical-conversations/wp-content/uploads/sites/18/2023/03/PG2814-PJT10311-COL024299-MPX-sh2164832913-1200x675-1-1024x576.jpg 1024w, https://www.thermofisher.com/blog/clinical-conversations/wp-content/uploads/sites/18/2023/03/PG2814-PJT10311-COL024299-MPX-sh2164832913-1200x675-1-768x432.jpg 768w" sizes="(max-width: 1200px) 100vw, 1200px" /></p> <p>While this sudden, global outbreak caused alarm, the world rallied quickly to accurately diagnose and vaccinate against mpox. Did hard learned lessons from the COVID-19 pandemic boost the efficiency of global response? At last year’s Association for Molecular Pathology’s Annual Meeting & Expo (AMP 2022), two experts from Aegis Sciences Corporation made the case that it did. During both the COVID-19 and mpox outbreaks, Aegis sprang into action to support testing and surveillance efforts.</p> <p><a href="https://www.thermofisher.com/us/en/home/global/forms/life-science/webinar-monkeypox-outbreak-preparedness-response">Watch the AMP recording here</a>.</p> <h2>From small lab to leading results provider</h2> <p>When COVID-19 hit, Aegis’ BioPharma Lab was lean, but nimble, in its response. According to Matthew Hardison, PhD, FACMG, TC-NRCC, Senior Vice President, Lab Operations, Aegis took some time to consider next steps before launching and validating its first assay in spring of 2020. Starting from five employees using six instruments, the lab tripled its staff and resources within a few months, expanding significantly to perform over 15,000 tests a day.</p> <p>At the peak, according to Dr. Hardison, Aegis was able to run 130,000 samples per day. The lab worked closely with partners to not only increase the number of samples it could test but to support national surveillance efforts. “We’ve used the TaqPath COVID-19 Combo Kit almost since the beginning and the free target assay there has allowed us to create an additional, much faster look at where the pandemic is heading [and] what different variants are rising or falling,” said Dr. Hardison.</p> <h2>PCR’s trusted reputation as a diagnostic tool</h2> <p>Throughout the COVID-19 pandemic, the world witnessed the importance of infectious disease testing and the benefits of molecular testing firsthand. “One of the things that the pandemic did which was good is increase the public’s awareness, and not just the lay public but also the clinical and medical public’s awareness and understanding of PCR and molecular-based assays,” said Dr. Hardison. Thanks to PCR’s performance in testing for COVID-19, it is now recognized as a trusted, accurate diagnostic tool.</p> <p>The good news is that when it comes to defending against future disease outbreaks, existing trust and capacity for PCR testing can be relied on. According to Cyndi Clark, PhD, Manager, BioPharma Laboratory at Aegis, the PCR workflow for COVID-19 can be used for research into other infectious diseases. “We were able to utilize the exact same workflow just by adding in a couple of different collection methods depending on the panel, so we changed our kits – but really, once it gets into the lab, the workflow stays the same,” said Dr. Clark, explaining how her team was able to use its established workflow for research in a range of respiratory and gastrointestinal diseases as well as urinary tract infections and sexually transmitted diseases.</p> <h2>New outbreak, same workflow</h2> <p>Like most of the world, Aegis learned from the COVID-19 pandemic. “You don’t know what you don’t know and boy, that was a lot,” said Dr. Hardison. But lessons from COVID-19 are already paying dividends in improving response to other infectious diseases, with mpox as the most recent example.</p> <p>When mpox became a global threat, leveraging existing relationships built during COVID-19 was essential: “One thing that the CDC, NIH, and other governing bodies did with this monkeypox outbreak is react much more quickly to leverage and engage those public-private partnerships to expand our nation’s testing capacity, so we wouldn’t get in a place like we were at the beginning of COVID,” reflected Dr. Hardison.</p> <p>According to Dr. Clark, following the COVID-19 pandemic, the Centers for Disease Control and Prevention (CDC) knew which labs to come to for testing support, improving the speed of early response. Furthermore, despite some updates to collection techniques, Aegis was able to leverage its COVID-19 PCR workflow for mpox. Going forward, Dr. Clark sees the world getting better and better at response times for infectious disease – thanks to key learnings from the last few years.</p> <p>For more on the molecular testing response to COVID-19 and monkeypox, as well as lessons learned, watch Aegis Sciences Corporation’s <a href="https://www.thermofisher.com/us/en/home/global/forms/life-science/webinar-monkeypox-outbreak-preparedness-response">presentations from AMP 2022 on-demand</a>.</p> <p>For information on Thermo Fisher Scientific’s infectious disease testing solutions, please click <a href="https://www.thermofisher.com/us/en/home/clinical/clinical-genomics/pathogen-detection-solutions.html?CID=fl-pathogendetection">here</a>.</p> <p>Sources:</p> <ol> <li><a href="https://www.who.int/emergencies/situations/monkeypox-oubreak-2022">World Health Organization | Mpox (monkeypox) outbreak</a></li> <li><a href="https://www.cdc.gov/poxvirus/monkeypox/response/2022/world-map.html">Centers for Disease Control and Prevention | 2022 Monkeypox Outbreak Global Map</a></li> <li><a href="https://www.cnbc.com/2022/12/02/biden-administration-will-end-monkeypox-public-health-emergency.html"><em>CNBC</em> | Centers for Disease Control and Prevention | 2022 Monkeypox Outbreak Global Map</a></li> </ol>  </div></article></main></div></div><footer class="site-footer"><div class="wrap"><div class="creds"><p class="footer-links"><a href="https://corporate.thermofisher.com/en/footer/privacy-statement.html" target="_blank" rel="noopener noreferrer">Privacy Statement</a><a href="https://corporate.thermofisher.com/en/footer/terms-and-conditions.html" target="_blank" rel="noopener noreferrer">Terms & Conditions</a><a href="/blog/locations/">Locations</a><a href="/blog/sitemap/">Sitemap</a></p><p>© 2024 <a href="https://www.thermofisher.com">Thermo Fisher Scientific</a>. 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