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eF-seek
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top: 1px; width: 630px; z-index: 1; " /> <div style="height: 120px"> <a href="http://www.pdbj.org/index.html" title="http://www.pdbj.org/index.html"> <img src="TOP_files/pdbj.protein.osaka-u.ac.jpg" alt="" style="border: none; height: 34px; width: 100px; opacity: 1.00; position: absolute; top: 58px; left: 58px; z-index: 1; " /> </a> <img src="TOP_files/logo-seek.jpg" alt="" style="border: none; height: 79px; width: 251px; opacity: 1.00; position: absolute; top: 18px; left: 224px; z-index: 1; " /> </div> </div> <div style="position: relative; left: 35px; "> <table border="0"> <tr> <td width="340px" valign="top"> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: bold; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> ABOUT eF-seek: <br> Molecular function </span> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> of proteins are determined by their three dimensional structures, thus the similarity of protein structure can give some clues to infer their functions. In many cases, the molecular function are begun with the molecular interaction with small molecules (ligands). </span> <span style="color: #f91a00; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> eF-seek </span> <span style="color: #404040; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> is a web server to search for the similar ligand binding sites for the uploaded coordinate file with PDB format. The representative binding sites in </span> <a href="https://pdbj.org/eF-site/" title="https://pdbj.org/eF-site/" style="font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-transform: none; "> eF-site </a> <span style="color: #404040; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> database are search by our own algorithm based on the clique search algorithm. </span> </td> <td width="10px"></td> <td> <img src="TOP_files/1atp.gif" alt="" style="height: 300px; width: 300px; z-index: 1; " /> </td> </tr> </table> </div> <div style="position: relative; left: 35px; "> <div style="height: 0px; line-height: 0px; " class="tinyText"> </div> </div> <div style="height: 10px; margin-left: 0px; position: relative; width: 700px; z-index: 15; "> <div style="height: 0px; line-height: 0px; " class="tinyText"> </div> </div> <div style="position: relative; left: 35px; "> <form name="registerForm" method="POST" action="/eF-seek/register.do;jsessionid=5A2346966A1E3E545393DB980B8EACD0" enctype="multipart/form-data"> <table border="0" width="630"> <tr> <td colspan="2"> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: bold; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none;"> Submission STEP-1: </span> </td> </tr> <tr> <td width="220px" align="center"> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> Specify a PDB format file: </span> </td> <td width="430px"> <input type="file" name="file" size="50" value=""> </td> </tr> <tr> <td align="center"> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> E-mail address: </span> </td> <td> <input type="text" name="email" size="50" value=""> </td> </tr> <tr> <td align="center"> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> Title: (optional) </span> </td> <td> <input type="text" name="title" size="50" value=""> </td> </tr> <tr> <td align="center"> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> Search database: </span> </td> <td> <select name="patch_set"><option value="default">Current DB</option> <option value="orig">old-DB</option> <option value="orig2">old-DB2</option> <option value="scPDB">scPDB</option></select> </td> </tr> <tr> <td colspan="2" height="10"></td> </tr> <tr> <td colspan="2"> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 13px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> * Note that the maximum number of atoms is restricted to 28000. </span> <!-- * When you upload a PDB file of version 3, please make sure that the file contains 'REMARK 4' records to express the version (click <a href="https://www.wwpdb.org/documentation/file-format-content/format33/remarks1.html#REMARK%204">here</a> for details). --> </td> </tr> <tr> <td colspan="2" height="10"></td> </tr> <tr> <td colspan="2"> <input type="submit" value="submit"> </td> </tr> </table> </form> </div> <div style="height: 30px; margin-left: 0px; position: relative; width: 700px; z-index: 15; "> <div style="height: 0px; line-height: 0px; " class="tinyText"> </div> </div> <div style="position: relative; left: 35px; "> <table border="0"> <tr> <td> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: bold; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none;"> Acknowledgment: </span> </td> </tr> <tr> <td> <span style="color: #453c3b; font-family: 'ArialMT', 'Arial', 'sans-serif'; font-size: 15px; font-style: normal; font-variant: normal; font-weight: normal; letter-spacing: 0; line-height: 20px; opacity: 1.00; text-decoration: none; text-transform: none; "> eF-seek is supported by <a href="https://biosciencedbc.jp/en/" title="https://biosciencedbc.jp/en/">NBDC</a> / <a href="http://www.jst.go.jp/EN/" title="http://www.jst.go.jp/EN/">JST</a> as a part of <a href="http://www.pdbj.org/index.html" title="http://www.pdbj.org/index.html">PDBj</a> project. </span> </td> </tr> </table> </div> <div style="height: 150px; margin-left: 0px; position: relative; width: 700px; z-index: 15; " id="footer_layer"> <div style="height: 0px; line-height: 0px; " class="tinyText"> </div> </div> </div> </div> </body> </html>