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Materials science in clinical resea | List of High Impact Articles | 6493

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Readerbase</a> <!------qrcode---------> <!------qrcode end---------> <div class="card mb-3"> <div class="card-header custom-header"> <h6>PMC/PubMed Indexed Articles</h6> </div> <div class="card-body"> <p class="card-text"><a class="deep-orange-400-before pr-2" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10911063/" title="GWAS-follow-up Studies Identified a Connection between Abnormal LIF/JAK2/STAT1 Signaling and Overproduction of Galactose-Deficient IgA1 in the Tonsillar IgA1-Secreting Cells from Patients with IgA Nephropathy" target="_blank">GWAS-follow-up Studies Identified a Connection between Abnormal LIF/JAK2/STAT1 Signaling and Overproduction of Galactose-Deficient IgA1 in the Tonsillar IgA1-Secreting Cells from Patients with IgA Nephropathy</a> </p> </div> <div class="card-body"> <p class="card-text"><a class="deep-orange-400-before pr-2" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280672/" title="Ethics Standards (HRPP) and Public Partnership (PARTAKE) to Address Clinical Research Concerns in India: Moving Toward Ethical, Responsible, Culturally Sensitive, and Community-Engaging Clinical Research" target="_blank">Ethics Standards (HRPP) and Public Partnership (PARTAKE) to Address Clinical Research Concerns in India: Moving Toward Ethical, Responsible, Culturally Sensitive, and Community-Engaging Clinical Research</a> <p class="m-0 clearfix"><a href="https://www.ncbi.nlm.nih.gov/pmc/?term=J+Clin+Res+Bioeth" target="_blank"><span class="btn btn-warning btn-xs float-right">View More &raquo;</span></a></p></p> </div> </div> <div class="card mb-3"> <div class="card-header custom-header"> <h6><a target="_blank" href="https://scholar.google.com/citations?user=aVWQrDgAAAAJ&hl=en" title="Click here">Google Scholar citation report</a></h6> </div> <div class="card-body custom-body"> <h6 style="font-weight:bold;">Citations : 2248</h6> <p><a target="_blank" href="https://scholar.google.com/citations?user=aVWQrDgAAAAJ&hl=en" title="Click here">Journal of 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href="https://www.walshmedicalmedia.com/scholarly/tropical-medicine-and-hygiene-journals-articles-ppts-list-470.html" title="Tropical Medicine and Hygiene">Tropical Medicine and Hygiene</a> </li> <li><i class="fa fa-angle-right"></i> <a href="https://www.walshmedicalmedia.com/scholarly/tropical-medicine-and-infectious-diseases-journals-articles-ppts-list-465.html" title="Tropical Medicine and Infectious Diseases">Tropical Medicine and Infectious Diseases</a> </li> <li><i class="fa fa-angle-right"></i> <a href="https://www.walshmedicalmedia.com/scholarly/tropical-medicine-and-parasitology-journals-articles-ppts-list-456.html" title="Tropical Medicine and Parasitology">Tropical Medicine and Parasitology</a> </li> <li><i class="fa fa-angle-right"></i> <a href="https://www.walshmedicalmedia.com/scholarly/tropical-veterinary-medicine--journals-articles-ppts-list-507.html" title="Tropical Veterinary Medicine">Tropical Veterinary Medicine</a> </li> <li><i class="fa fa-angle-right"></i> <a href="https://www.walshmedicalmedia.com/scholarly/tumorigenesis-journals-articles-ppts-list-6357.html" title="Tumorigenesis">Tumorigenesis</a> </li> <li><i class="fa fa-angle-right"></i> <a href="https://www.walshmedicalmedia.com/scholarly/urocare-journals-articles-ppts-list-6376.html" title="Urocare">Urocare</a> </li> <li><i class="fa fa-angle-right"></i> <a href="https://www.walshmedicalmedia.com/scholarly/vector-borne-diseases-journals-articles-ppts-list-537.html" title="Vector Borne Diseases">Vector Borne Diseases</a> </li> <li><i class="fa fa-angle-right"></i> <a href="https://www.walshmedicalmedia.com/scholarly/clinical-pathology-journals-articles-ppts-list-2307.html" title="clinical pathology">clinical pathology</a> </li> </ul> </div> </div> </div> <div class="col-lg-9"> <h2 class="mt-3">Materials science in clinical research</h2> <p><strong>Materials science</strong> in the area of <strong>clinical research</strong> focuses on the study and development of materials designed for use in healthcare applications, including medical devices, implants, drug delivery systems, and diagnostic tools. The field bridges the gap between <strong>engineering</strong>, <a href="https://www.walshmedicalmedia.com/clinical-research-bioethics.html"><strong>chemistry</strong></a>, <strong>biology</strong>, and <strong>medicine</strong>, aiming to create materials that are safe, effective, and capable of interacting with biological systems to improve patient care.</p> <h3>Key Areas of Materials Science in Clinical Research:</h3> <ol> <li> <p><strong>Biocompatible Materials</strong>:</p> <ul> <li>One of the primary concerns is ensuring that materials used in medical applications do not cause adverse reactions when introduced into the body. Biocompatibility, meaning that a material does not elicit an immune response, is critical for <strong>implants</strong>, <strong>prosthetics</strong>, and <strong>surgical tools</strong>.</li> <li>Examples: Titanium for bone implants, silicone for breast implants, or polyethylene for joint replacements.</li> </ul> </li> <li> <p><strong>Drug Delivery Systems</strong>:</p> <ul> <li>Materials science is crucial in creating <strong>nanoparticles</strong>, <strong>microspheres</strong>, or <strong>hydrogels</strong> that can encapsulate drugs and release them in a controlled and targeted manner. These systems can improve the <strong>efficacy</strong> and <strong>bioavailability</strong> of drugs while minimizing side effects.</li> <li>Examples: Polymeric nanoparticles for chemotherapy drugs, lipid-based nanoparticles for mRNA vaccines.</li> </ul> </li> <li> <p><strong>Tissue Engineering and Regenerative Medicine</strong>:</p> <ul> <li>In regenerative medicine, materials science plays a key role in developing <strong>scaffolds</strong> that support cell growth and tissue regeneration. These scaffolds, often made from biodegradable polymers, help in the repair of damaged tissues like skin, bones, or even organs.</li> <li>Examples: Biodegradable polymers such as polylactic acid (PLA) and collagen-based scaffolds for wound healing or bone regeneration.</li> </ul> </li> <li> <p><strong>Biosensors and Diagnostic Materials</strong>:</p> <ul> <li>Materials science enables the development of <strong>biosensors</strong>, <strong>lab-on-a-chip technologies</strong>, and <a href="https://www.walshmedicalmedia.com/clinical-research-bioethics.html"><strong>biomaterials</strong></a> that enhance diagnostic capabilities. These innovations allow for early detection of diseases, real-time monitoring of physiological conditions, and more precise medical interventions.</li> <li>Examples: Gold nanoparticles in diagnostic kits, polymer-based microfluidic devices for blood analysis.</li> </ul> </li> <li> <p><strong>Smart and Responsive Materials</strong>:</p> <ul> <li>These materials can change their properties in response to external stimuli such as pH, temperature, or electrical signals, making them valuable for drug delivery, wound care, and medical devices that adapt to the body&rsquo;s needs.</li> <li>Examples: Shape-memory polymers that adjust to the body&rsquo;s temperature or hydrogels that swell in response to pH changes for controlled drug release.</li> </ul> </li> <li> <p><strong>Implantable Devices and Prosthetics</strong>:</p> <ul> <li>Materials science drives the innovation of <strong>long-lasting</strong>, <strong>corrosion-resistant</strong>, and <strong>biocompatible</strong> materials for medical implants like heart valves, stents, and joint replacements. The goal is to create materials that interact seamlessly with human tissues while maintaining their functionality over time.</li> <li>Examples: Titanium alloys for hip replacements, polyurethane for artificial heart valves.</li> </ul> </li> </ol> <h3>Importance of Clinical Research:</h3> <p>In clinical research, materials are rigorously tested for <strong>biocompatibility</strong>, <strong>mechanical strength</strong>, <strong>stability</strong>, and <strong>toxicity</strong> to ensure that they can be safely and effectively used in humans. This testing is done through <a href="https://www.walshmedicalmedia.com/clinical-research-bioethics.html"><strong>clinical trials</strong></a> and other forms of testing in living systems to ensure the materials behave as expected in real-world medical scenarios.</p> <h3>Summary:</h3> <p>Materials science in clinical research is critical for advancing <strong>healthcare technologies</strong>. 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