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High-throughput sequencing precisely and super-rapidly analyzes the biological contents of those microdroplets鈥攕uch as the genetic blueprints (genomes) and activity of millions of individual cells.</p><p style="margin-top: 0px; padding: 0px 0px 20px; font-family: Gotham-Book; color: rgb(128, 128, 128); font-size: 16px; line-height: 32px;">One ongoing effort at QBI in the <a href="http://sites.google.com/site/abatelab/home" target="_black" style="background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial; text-decoration: underline; color: rgb(128, 128, 128);">Abate Lab</a> is to comprehensively characterize the antibody repertoires of people with autoimmune disorders, such as lupus and rheumatoid arthritis. This will be done by analyzing millions of their B cells to identify their antibody-generating genetic sequences and what the resulting antibodies bind to鈥攄ifferentiating between the sequences for antibodies that healthily bind to and help destroy pathogens versus those that errantly bind to and damage healthy tissues. The goal is to enable discovery of the mechanisms underlying disease in those immune cells gone awry and to enable treatments more precisely targeting them.</p> </div><!-- end map content inn --> </div><!-- end map content --> </div><!-- end mapping main --> </div><!-- end row --> </div> <!-- Modules End over here --> </div> </section><!--end topcontain--> <footer><!-- start footer --> <div class="container"><!-- start container --> <div class="row footer-logo"><!-- start row --> <ul><li><a href="" target="_blank"><img src="" alt="" class="img-responsive"></a></li></ul> </div><!-- end row --> <div class="row foooter-address-bar"> <div class="col-xs-12 col-sm-12 col-md-4 col-lg-5"> <i class="fa fa-map-marker footer-map-icon" aria-hidden="true"></i> <p> <a href="http://www.google.com/maps/place/QB3/@37.7671424,-122.3962505,15.61z/data=!4m5!3m4!1s0x808f7fcf444d105f:0x87a610f66290621b!8m2!3d37.7673012!4d-122.3915362" target="_blank"> University of California, <br>1700 4th Street, <br>San Francisco, CA, 94158 </a> </p> </div> <div class="col-xs-12 col-sm-12 col-md-3 col-lg-2 padding-right"> <p> <i class="fa fa-envelope footer-envelope-icon" aria-hidden="true"></i> <a href="mailto:admin-qbi@ucsf.edu"> admin-qbi@ucsf.edu </a> </p> </div> <div class="col-xs-12 col-sm-12 col-md-3 col-lg-2 col-lg-offset-1"> <p> <i class="fa fa-phone footer-tel-icon" aria-hidden="true"></i> 415-476-6109 </p> </div> <div class="col-xs-12 col-sm-12 col-md-2 col-lg-2 footer-social-icon"> <ul> <ul> <li><a target="_blank" href="http://twitter.com/QBI_UCSF"><i class="fa fa-twitter twitter" aria-hidden="true"></i></a></li> <li><a target="_blank" href="http://www.facebook.com/qbiucsf/"><i class="fa fa-facebook facebook" aria-hidden="true"></i></a></li> <li class="last"><a target="_blank" href="http://www.instagram.com/qbi_ucsf"><i class="fa fa-instagram insta" aria-hidden="true"></i></a></li> </ul> </ul> </div> </div> <div class="row footer-links" id="footer-toggle" style="display: none;"> <div class="col-md-12"> <h2>RESOURCES </h2> </div> <div class="col-xs-12 col-md-12"> <ul id="main-navbar"><li><a href="https://qbi.ucsf.edu">Home Page</a></li><li><a href="https://qbi.ucsf.edu/aboutus">About Us</a></li><li><a href="https://qbi.ucsf.edu/investigators">Investigators</a></li><li><a href="https://qbi.ucsf.edu/research">Research</a></li><li><a href="https://qbi.ucsf.edu/technology">Technology</a></li><li><a href="https://qbi.ucsf.edu/grants">Grants</a></li><li><a href="https://qbi.ucsf.edu/mapping">Cell Mapping</a></li><li><a href="https://qbi.ucsf.edu/contact">Contact</a></li></ul> </div> </div> </div><!-- end container --> </footer><!-- end footer --> <div class="footer-close-panel" id="footer-close-panel"> <div class="container"> <div class="row"> <div class="col-xs-12 col-sm-5 col-md-4 padding-right copyright-txt"> <p>漏2019 The Regents of the University of California</p> </div> <div class="col-xs-12 col-sm-2 col-sm-offset-1 col-md-1 col-md-offset-2 more-button no-padding"> <div class="mobile-more-btn"> <p> <a id="menu-open-close"><span id="spantext">More</span> <img src="images/scroll-down.png" class="img-responsive footer-more"></a> </p> </div> </div> <div class="col-xs-12 col-sm-3 col-md-3 col-md-offset-2 text-right pull-right"> <p>Site design by <span><a href="http://www.goodvsevil.co" target="_blank">Good vs Evil</a></span></p> </div> </div> </div> </div> <!-- START POPUP --> <!--<div class="support-covid remodal" data-remodal-id="support-covid">--> <!-- <div class="covid-left"> <!-- <img src="images/ucsf_logo.png" alt="Logo" class="covid-logo">--> <!-- <h2>Support COVID-19<br>Research</h2>--> <!-- <h3>Be part of the solution</h3>--> <!-- <a target="_blank" href="http://makeagift.ucsf.edu/QCRG" class="or-btn">DONATE NOW</a>--> <!-- <a href="http://qbi.ucsf.edu/COVID-19" class="rgt-btn">Find out more</a>--> <!-- </div> -->--> <!-- <div class="story-container">--> <!-- <div class="inner-container">--> <!-- <iframe src="https://onl.st/qbi-anniversary/"></iframe> --> <!-- </div> --> <!-- </div>--> <!--</div>--> <!-- END POPUP --> <!--<script src="scripts/jquery.remodal.js"></script>--> <script> // $(document).ready(function(){ // let remodalEl = $(".support-covid.remodal"); // /*let showedPopup = localStorage && localStorage.getItem('alreadyShowedStory');*/ // let showedPopup = true; // if(!showedPopup && remodalEl.length && $.remodal && Array.isArray($.remodal.lookup)){ // let inst = $.remodal.lookup[remodalEl.data("remodal")]; // setTimeout(function(){ // inst.open(); // if(localStorage){ // localStorage.setItem("alreadyShowedStory", true); // } // }, 1000); // } // }); </script> <script type='text/javascript' src='scripts/footer.js'></script> <script> $(document).ready(function() { $('.nav-tabs li').on('click',function () { element=$(this).find('a'); setTimeout(function () { background = element.css('background-color'); $('.nav-tabs').css('border-bottom',"2px solid " + background); },100) }) }); </script> </body> </html>