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Search results for: Cartelli S.

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class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Cartelli S."> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 4</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Cartelli S.</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Comparison of the Effectiveness between Exosomes from Different Origins in Reversing Skin Aging</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Iannello%20G.">Iannello G.</a>, <a href="https://publications.waset.org/abstracts/search?q=Coppa%20F."> Coppa F.</a>, <a href="https://publications.waset.org/abstracts/search?q=Pennisi%20S."> Pennisi S.</a>, <a href="https://publications.waset.org/abstracts/search?q=Giuffrida%20G."> Giuffrida G.</a>, <a href="https://publications.waset.org/abstracts/search?q=Lo%20Faro%20R."> Lo Faro R.</a>, <a href="https://publications.waset.org/abstracts/search?q=Cartelli%20S."> Cartelli S.</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferruggia%20G."> Ferruggia G.</a>, <a href="https://publications.waset.org/abstracts/search?q=Brundo%20M.%20V."> Brundo M. V.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Skin is the largest multifunctional human organ and possesses a complex, multilayered structure with the ability to regenerate and renew. The key role in skin regeneration is played by fibroblasts, which also occupy an important role in the wound healing process. Different methods, including dynamic light scattering, scanning electron microscopy, ELISA, and MTT assay, were employed to evaluate on fibroblasts the in vitro effects of plant-derived nanovesicles and cord blood stem cells‐derived exosomes. We compared the results with those of cells exposed to a technology called AMPLEX PLUS, containing a mixture of 20 different biologically active factors (GF20) and exosomes isolated and purified from bovine colostrum. AMPLEX PLUS was able to significantly enhance the cell proliferation status of cells at both 24 and 48 hours compared to untreated cells (control). The obtained results suggest how AMPLEX PLUS could be potentially effective in treating skin rejuvenation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AMPLEX%20PLUS" title="AMPLEX PLUS">AMPLEX PLUS</a>, <a href="https://publications.waset.org/abstracts/search?q=cell%20vitality" title=" cell vitality"> cell vitality</a>, <a href="https://publications.waset.org/abstracts/search?q=colostrum" title=" colostrum"> colostrum</a>, <a href="https://publications.waset.org/abstracts/search?q=nanovesicles" title=" nanovesicles"> nanovesicles</a> </p> <a href="https://publications.waset.org/abstracts/187382/comparison-of-the-effectiveness-between-exosomes-from-different-origins-in-reversing-skin-aging" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187382.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">39</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Skin Substitutes for Wound Healing: An Advanced Formulation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pennisi%20Stefania">Pennisi Stefania</a>, <a href="https://publications.waset.org/abstracts/search?q=Giuffrida%20Graziella"> Giuffrida Graziella</a>, <a href="https://publications.waset.org/abstracts/search?q=Coppa%20Federica"> Coppa Federica</a>, <a href="https://publications.waset.org/abstracts/search?q=Iannello%20Giulia"> Iannello Giulia</a>, <a href="https://publications.waset.org/abstracts/search?q=Cartelli%20Simone"> Cartelli Simone</a>, <a href="https://publications.waset.org/abstracts/search?q=Lo%20Faro%20Riccardo"> Lo Faro Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferruggia%20Greta"> Ferruggia Greta</a>, <a href="https://publications.waset.org/abstracts/search?q=Brundo%20Maria%20Violetta"> Brundo Maria Violetta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Tissue engineering aims to develop advanced medical devices to restore normal functions of damaged tissue. These devices, even more effective than conventional methods, are called skin substitutes and are configured as drugs to be applied to the damaged area, to heal extensive and deep wounds which could otherwise lead to chronic wounds lasting over time. Among the variety of commercially available skin substitutes, those that have proven to be most effective are those consisting of a bilayer scaffold. The aim of our research was to design a skin substitute which can promote cell proliferation, cell migration and angiogenesis, and which can guarantee timely closure of the wound with satisfactory aesthetic results, in order to avoid the patient excessive pain, risk of contracting infections and long-term hospitalization. The product was tested in vitro using the Scratch Assay. The assay was carried out both on the matrix modified with hyaluronic acid and on the matrix based only on collagen. In both cases, after 48 hours of exposure the wound scratch was almost completely closed in treated cells compared to untreated control. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=collagen" title="collagen">collagen</a>, <a href="https://publications.waset.org/abstracts/search?q=hyaluronic%20acid" title=" hyaluronic acid"> hyaluronic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=scratch-%20wound-healing%20assay" title=" scratch- wound-healing assay"> scratch- wound-healing assay</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20regeneration" title=" tissue regeneration"> tissue regeneration</a> </p> <a href="https://publications.waset.org/abstracts/187381/skin-substitutes-for-wound-healing-an-advanced-formulation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187381.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">27</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Effectiveness of Opuntia ficus indica Cladodes Extract for Wound-Healing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Giuffrida%20Graziella">Giuffrida Graziella</a>, <a href="https://publications.waset.org/abstracts/search?q=Pennisi%20Stefania"> Pennisi Stefania</a>, <a href="https://publications.waset.org/abstracts/search?q=Coppa%20Federica"> Coppa Federica</a>, <a href="https://publications.waset.org/abstracts/search?q=Iannello%20Giulia"> Iannello Giulia</a>, <a href="https://publications.waset.org/abstracts/search?q=Cartelli%20Simone"> Cartelli Simone</a>, <a href="https://publications.waset.org/abstracts/search?q=Lo%20Faro%20Riccardo"> Lo Faro Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferruggia%20Greta"> Ferruggia Greta</a>, <a href="https://publications.waset.org/abstracts/search?q=Brundo%20Maria%20Violetta"> Brundo Maria Violetta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cladode chemical composition may vary according to soil factors, cultivation season, and plant age. The primary metabolites of cladodes are water, carbohydrates, and proteins. The carbohydrates in cladodes are divided into two types: structural and storage. Polysaccharides from Opuntia ficus‐indica (L.) Mill plants build molecular networks with the capacity to retain water; thus, they act as mucoprotective agents. Mucilage is the main polysaccharide of cladodes; it contains polymers of β‐d‐galacturonic acid bound in positions (1–4) and traces of R‐linked l‐rhamnose (1-2). Mucilage regulates both the cell water content during prolonged drought and the calcium flux in the plant cells. The in vitro analysis of keratinocytes in monolayer, through the scratch-wound-healing assay, provided promising results. After 48 hours of exposure, the wound scratch was almost completely closed in cells treated with cladode extract. After 72 hours, the treated cells reached complete confluence, while in the untreated cells (negative control) the confluence was reached after 96 hours. We also added a positive control group of cells treated with colchicine, which inhibited wound closure for a more comprehensive analysis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cladodes" title="cladodes">cladodes</a>, <a href="https://publications.waset.org/abstracts/search?q=metabolites" title=" metabolites"> metabolites</a>, <a href="https://publications.waset.org/abstracts/search?q=polysaccharide" title=" polysaccharide"> polysaccharide</a>, <a href="https://publications.waset.org/abstracts/search?q=scratch-wound-healing%20assay" title=" scratch-wound-healing assay"> scratch-wound-healing assay</a> </p> <a href="https://publications.waset.org/abstracts/187380/effectiveness-of-opuntia-ficus-indica-cladodes-extract-for-wound-healing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187380.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">54</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Food Supplements and Natural Products to Slow Down Biological Aging</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Coppa%20Federica">Coppa Federica</a>, <a href="https://publications.waset.org/abstracts/search?q=Iannello%20Giulia"> Iannello Giulia</a>, <a href="https://publications.waset.org/abstracts/search?q=Pennisi%20Stefania"> Pennisi Stefania</a>, <a href="https://publications.waset.org/abstracts/search?q=Giuffrida%20Graziella"> Giuffrida Graziella</a>, <a href="https://publications.waset.org/abstracts/search?q=Lo%20Faro%20Riccardo"> Lo Faro Riccardo</a>, <a href="https://publications.waset.org/abstracts/search?q=Cartelli%20Simone"> Cartelli Simone</a>, <a href="https://publications.waset.org/abstracts/search?q=Ferruggia%20Greta"> Ferruggia Greta</a>, <a href="https://publications.waset.org/abstracts/search?q=Brundo%20Maria%20Violetta"> Brundo Maria Violetta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, a new field of basic research has emerged: the biology and physiology of extracellular vesicles and their application in diagnostics and therapy. In particular, exosomes attract the scientific community as nanovesicles of endosomal origin, which can be secreted by a variety of cells and are found in all biological fluids. Exosomes have recently gained attention also in the cosmetic field: in fact, they are used in creams, serums and masks for topical use, proving to have a series of therapeutic and anti-aging benefits. To date, the oral administration of exosomes is the subject of attention because it represents a non-invasive and efficient method for delivering bioactive molecules into the intestine. We decided to focus our research on the creation of a food supplement that contains various bioactive factors, vitamins, and a new technology called AMPLEX PLUS, containing a mixture of 20 different biologically active factors (GF20) and exosomes isolated and purified from bovine colostrum. We have demonstrated in vitro that this new supplement acts on telomerase, slowing down cell aging. Amplex plus increased the proliferation rate of cells and the addition of it reduced the rate of telomere shortening. Under oxidative stress conditions (H2O2 – induced), the TSR increased; however, treatment with colostrum appeared to attenuate this increase. In particular, after 2 weeks of treatment, AMPLEX plus increased the proliferation rate of cells and exerted a protective effect on telomere length erosion, reducing the rate of its shortening. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AMPLEX%20PLUS" title="AMPLEX PLUS">AMPLEX PLUS</a>, <a href="https://publications.waset.org/abstracts/search?q=colostrum" title=" colostrum"> colostrum</a>, <a href="https://publications.waset.org/abstracts/search?q=exosomes" title=" exosomes"> exosomes</a>, <a href="https://publications.waset.org/abstracts/search?q=telomerase" title=" telomerase"> telomerase</a> </p> <a href="https://publications.waset.org/abstracts/187383/food-supplements-and-natural-products-to-slow-down-biological-aging" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187383.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">52</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">&copy; 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