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Белимумаб — Википедия

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CentralNotice --></div> <div class="mw-indicators"> </div> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Белимумаб</span></h1> <div id="bodyContent" class="vector-body"> <div id="siteSub" class="noprint">Материал из Википедии — свободной энциклопедии</div> <div id="contentSub"><div id="mw-content-subtitle"><div id="mw-fr-revision-messages"><div class="cdx-message mw-fr-message-box cdx-message--block cdx-message--notice mw-fr-basic mw-fr-stable-unreviewed plainlinks noprint"><span class="cdx-message__icon"></span><div class="cdx-message__content">Данная страница <a href="/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%8F:%D0%9F%D1%80%D0%BE%D0%B2%D0%B5%D1%80%D0%BA%D0%B0_%D1%81%D1%82%D0%B0%D1%82%D0%B5%D0%B9/%D0%9F%D0%BE%D1%8F%D1%81%D0%BD%D0%B5%D0%BD%D0%B8%D0%B5_%D0%B4%D0%BB%D1%8F_%D1%87%D0%B8%D1%82%D0%B0%D1%82%D0%B5%D0%BB%D0%B5%D0%B9" title="Википедия:Проверка статей/Пояснение для читателей">не проверялась</a> участниками с соответствующими правами.</div></div></div></div></div> <div id="contentSub2"></div> <div id="jump-to-nav"></div> <a class="mw-jump-link" href="#mw-head">Перейти к навигации</a> <a class="mw-jump-link" href="#searchInput">Перейти к поиску</a> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="ru" dir="ltr"><table class="infobox infobox-ccd8cb51c14ce12e" style="" data-name="Лекарственное средство"><tbody><tr><th colspan="2" scope="colgroup" class="infobox-above" style="">Белимумаб</th></tr><tr><td colspan="2" class="infobox-image" style=""> <span data-wikidata-property-id="P117" class="no-wikidata"><span typeof="mw:File/Frameless"><a href="/wiki/%D0%A4%D0%B0%D0%B9%D0%BB:Belimumab_5Y9K.png" class="mw-file-description"><img alt="Изображение химической структуры" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/db/Belimumab_5Y9K.png/290px-Belimumab_5Y9K.png" decoding="async" width="290" height="290" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/db/Belimumab_5Y9K.png/435px-Belimumab_5Y9K.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/db/Belimumab_5Y9K.png/580px-Belimumab_5Y9K.png 2x" data-file-width="2048" data-file-height="2048" /></a></span></span> </td></tr> <tr> <th colspan="2" scope="colgroup" class="infobox-header" style=""><a href="/wiki/%D0%A5%D0%B8%D0%BC%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%BE%D0%B5_%D1%81%D0%BE%D0%B5%D0%B4%D0%B8%D0%BD%D0%B5%D0%BD%D0%B8%D0%B5" title="Химическое соединение">Химическое соединение</a></th> </tr> <tr> <th scope="row" class="plainlist"><a href="/wiki/%D0%A5%D0%B8%D0%BC%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D1%84%D0%BE%D1%80%D0%BC%D1%83%D0%BB%D0%B0" title="Химическая формула">Брутто-формула</a></th> <td class="plainlist"> <span data-wikidata-claim-id="Q1996249$dd76354f-4c7c-3034-455e-a24d8f2f17f5" class="wikidata-claim" data-wikidata-property-id="P274"><span class="wikidata-snak wikidata-main-snak">C<sub>6714</sub>H<sub>10428</sub>O<sub>2102</sub>S<sub>52</sub></span></span></td> </tr> <tr> <th scope="row" class="plainlist"><a href="/wiki/%D0%A0%D0%B5%D0%B3%D0%B8%D1%81%D1%82%D1%80%D0%B0%D1%86%D0%B8%D0%BE%D0%BD%D0%BD%D1%8B%D0%B9_%D0%BD%D0%BE%D0%BC%D0%B5%D1%80_CAS" title="Регистрационный номер CAS">CAS</a></th> <td class="reflink plainlinks plainlist"> <span data-wikidata-external-id="356547-88-1" class="no-wikidata" data-wikidata-property-id="P231"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=356547-88-1">356547-88-1</a></span></td> </tr> <tr> <th scope="row" class="plainlist"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th> <td class="reflink plainlinks plainlist"> <span data-wikidata-property-id="P715" class="no-wikidata"><a rel="nofollow" class="external text" href="http://www.drugbank.ca/drugs/DB08879">DB08879</a></span></td> </tr> <tr> <th colspan="2" scope="colgroup" class="infobox-header" style="">Состав</th> </tr> <tr> <td colspan="2" class="noplainlist" style="text-align:center;text-align:left;"> <style data-mw-deduplicate="TemplateStyles:r117575837">.mw-parser-output .ts-Маркированный_список--bullet ul{list-style:none}.mw-parser-output .ts-Маркированный_список--bullet li:before{content:"•\a0 "}</style></td> </tr> <tr> <th colspan="2" scope="colgroup" class="infobox-header" style="">Классификация</th> </tr> <tr> <th scope="row" class="plainlist"><a href="/wiki/%D0%90%D0%BD%D0%B0%D1%82%D0%BE%D0%BC%D0%BE-%D1%82%D0%B5%D1%80%D0%B0%D0%BF%D0%B5%D0%B2%D1%82%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%BE-%D1%85%D0%B8%D0%BC%D0%B8%D1%87%D0%B5%D1%81%D0%BA%D0%B0%D1%8F_%D0%BA%D0%BB%D0%B0%D1%81%D1%81%D0%B8%D1%84%D0%B8%D0%BA%D0%B0%D1%86%D0%B8%D1%8F" title="Анатомо-терапевтическо-химическая классификация">АТХ</a></th> <td class="reflink plainlinks plainlist"> <span data-wikidata-claim-id="Q1996249$66BFBA2B-EAE5-4FE9-A6A8-2D733A7104D1" class="wikidata-claim" data-wikidata-property-id="P267"><span class="wikidata-snak wikidata-main-snak"><span class="reflink plainlinks"><a rel="nofollow" class="external text" href="http://www.whocc.no/atc_ddd_index/?code=L04AA26">L04AA26</a></span></span></span></td> </tr> <tr> <th colspan="2" scope="colgroup" class="infobox-header" style="">Другие названия</th> </tr> <tr> <td colspan="2" class="plainlist" style="text-align:center;text-align:left;"> LymphoStat-B, Benlysta</td> </tr><tr><td colspan="2" class="infobox-below" style=";"><span data-wikidata-claim-id="Q1996249$335e194b-ed3b-42e0-baa5-4861feee252c" class="wikidata-claim" data-wikidata-property-id="P373"><span class="wikidata-snak wikidata-main-snak"><span typeof="mw:File"><a href="https://commons.wikimedia.org/wiki/Category:Belimumab" title="commons:Category:Belimumab"><img alt="Логотип Викисклада" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span>&#160;<a href="https://commons.wikimedia.org/wiki/Category:Belimumab" class="extiw" title="commons:Category:Belimumab">Медиафайлы на Викискладе</a></span></span></td></tr> </tbody></table> <p><b>Белимумаб</b>&#160;— <a href="/wiki/%D0%9B%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2%D0%B5%D0%BD%D0%BD%D1%8B%D0%B9_%D0%BF%D1%80%D0%B5%D0%BF%D0%B0%D1%80%D0%B0%D1%82" class="mw-redirect" title="Лекарственный препарат">лекарственный препарат</a>, <a href="/wiki/%D0%9C%D0%BE%D0%BD%D0%BE%D0%BA%D0%BB%D0%BE%D0%BD%D0%B0%D0%BB%D1%8C%D0%BD%D1%8B%D0%B5_%D0%B0%D0%BD%D1%82%D0%B8%D1%82%D0%B5%D0%BB%D0%B0" title="Моноклональные антитела">моноклональное антитело</a>, ингибитор фактора активации В-лимфоцитов. Одобрен для применения: США (2011)<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup>. </p> <div id="toc" class="toc" role="navigation" aria-labelledby="mw-toc-heading"><input type="checkbox" role="button" id="toctogglecheckbox" class="toctogglecheckbox" style="display:none" /><div class="toctitle" lang="ru" dir="ltr"><h2 id="mw-toc-heading">Содержание</h2><span class="toctogglespan"><label class="toctogglelabel" for="toctogglecheckbox"></label></span></div> <ul> <li class="toclevel-1 tocsection-1"><a href="#Механизм_действия"><span class="tocnumber">1</span> <span class="toctext">Механизм действия</span></a></li> <li class="toclevel-1 tocsection-2"><a href="#Показания"><span class="tocnumber">2</span> <span class="toctext">Показания</span></a></li> <li class="toclevel-1 tocsection-3"><a href="#Беременность"><span class="tocnumber">3</span> <span class="toctext">Беременность</span></a></li> <li class="toclevel-1 tocsection-4"><a href="#Способ_применения"><span class="tocnumber">4</span> <span class="toctext">Способ применения</span></a></li> <li class="toclevel-1 tocsection-5"><a href="#Примечания"><span class="tocnumber">5</span> <span class="toctext">Примечания</span></a></li> </ul> </div> <div class="mw-heading mw-heading2"><h2 id="Механизм_действия"><span id=".D0.9C.D0.B5.D1.85.D0.B0.D0.BD.D0.B8.D0.B7.D0.BC_.D0.B4.D0.B5.D0.B9.D1.81.D1.82.D0.B2.D0.B8.D1.8F"></span>Механизм действия</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;veaction=edit&amp;section=1" title="Редактировать раздел «Механизм действия»" class="mw-editsection-visualeditor"><span>править</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;action=edit&amp;section=1" title="Редактировать код раздела «Механизм действия»"><span>править код</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/%D0%A4%D0%B0%D0%B9%D0%BB:Belimumab_5Y9K_binding_BAFF_homotrimer.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Belimumab_5Y9K_binding_BAFF_homotrimer.png/220px-Belimumab_5Y9K_binding_BAFF_homotrimer.png" decoding="async" width="220" height="220" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Belimumab_5Y9K_binding_BAFF_homotrimer.png/330px-Belimumab_5Y9K_binding_BAFF_homotrimer.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e6/Belimumab_5Y9K_binding_BAFF_homotrimer.png/440px-Belimumab_5Y9K_binding_BAFF_homotrimer.png 2x" data-file-width="2048" data-file-height="2048" /></a><figcaption>Три молекулы Белимумаба, связывающие <a href="/w/index.php?title=%D0%93%D0%BE%D0%BC%D0%BE%D1%82%D1%80%D0%B8%D0%BC%D0%B5%D1%80&amp;action=edit&amp;redlink=1" class="new" title="Гомотример (страница отсутствует)">гомотример</a> BAFF.</figcaption></figure> <p><a href="/wiki/%D0%98%D0%BD%D0%B3%D0%B8%D0%B1%D0%B8%D1%82%D0%BE%D1%80%D1%8B_%D1%84%D0%B0%D0%BA%D1%82%D0%BE%D1%80%D0%B0_%D0%BD%D0%B5%D0%BA%D1%80%D0%BE%D0%B7%D0%B0_%D0%BE%D0%BF%D1%83%D1%85%D0%BE%D0%BB%D0%B8" title="Ингибиторы фактора некроза опухоли">ингибитор</a> <a href="/wiki/TNFSF13B" title="TNFSF13B">фактора активации B-лимфоцитов</a> (BAFF) </p> <div class="mw-heading mw-heading2"><h2 id="Показания"><span id=".D0.9F.D0.BE.D0.BA.D0.B0.D0.B7.D0.B0.D0.BD.D0.B8.D1.8F"></span>Показания</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;veaction=edit&amp;section=2" title="Редактировать раздел «Показания»" class="mw-editsection-visualeditor"><span>править</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;action=edit&amp;section=2" title="Редактировать код раздела «Показания»"><span>править код</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>активная <a href="/wiki/%D0%A1%D0%B8%D1%81%D1%82%D0%B5%D0%BC%D0%BD%D0%B0%D1%8F_%D0%BA%D1%80%D0%B0%D1%81%D0%BD%D0%B0%D1%8F_%D0%B2%D0%BE%D0%BB%D1%87%D0%B0%D0%BD%D0%BA%D0%B0" title="Системная красная волчанка">системная красная волчанка</a> при наличии <a href="/wiki/%D0%90%D1%83%D1%82%D0%BE%D0%B0%D0%BD%D1%82%D0%B8%D1%82%D0%B5%D0%BB%D0%B0" title="Аутоантитела">аутоантител</a>.</li> <li><span data-interwiki-lang="en" data-interwiki-article="Lupus nephritis"><a href="/w/index.php?title=%D0%92%D0%BE%D0%BB%D1%87%D0%B0%D0%BD%D0%BE%D1%87%D0%BD%D1%8B%D0%B9_%D0%BD%D0%B5%D1%84%D1%80%D0%B8%D1%82&amp;action=edit&amp;redlink=1" class="new" title="Волчаночный нефрит (страница отсутствует)">волчаночный нефрит</a></span><sup class="noprint" style="font-style:normal; font-weight:normal;"><a href="https://en.wikipedia.org/wiki/Lupus_nephritis" class="extiw" title="en:Lupus nephritis"><span title="Lupus nephritis — версия статьи «Волчаночный нефрит» на английском языке">[англ.]</span></a></sup><sup id="cite_ref-dailymed_2-0" class="reference"><a href="#cite_note-dailymed-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup>.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Беременность"><span id=".D0.91.D0.B5.D1.80.D0.B5.D0.BC.D0.B5.D0.BD.D0.BD.D0.BE.D1.81.D1.82.D1.8C"></span>Беременность</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;veaction=edit&amp;section=3" title="Редактировать раздел «Беременность»" class="mw-editsection-visualeditor"><span>править</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;action=edit&amp;section=3" title="Редактировать код раздела «Беременность»"><span>править код</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Женщины детородного возраста во время лечения и 4 мес. после него должны использовать методы <a href="/wiki/%D0%9A%D0%BE%D0%BD%D1%82%D1%80%D0%B0%D1%86%D0%B5%D0%BF%D1%86%D0%B8%D1%8F" title="Контрацепция">контрацепции</a>.<sup id="cite_ref-dailymed_2-1" class="reference"><a href="#cite_note-dailymed-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="Способ_применения"><span id=".D0.A1.D0.BF.D0.BE.D1.81.D0.BE.D0.B1_.D0.BF.D1.80.D0.B8.D0.BC.D0.B5.D0.BD.D0.B5.D0.BD.D0.B8.D1.8F"></span>Способ применения</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;veaction=edit&amp;section=4" title="Редактировать раздел «Способ применения»" class="mw-editsection-visualeditor"><span>править</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;action=edit&amp;section=4" title="Редактировать код раздела «Способ применения»"><span>править код</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>подкожная <a href="/wiki/%D0%98%D0%BD%D1%8A%D0%B5%D0%BA%D1%86%D0%B8%D1%8F" title="Инъекция">инъекция</a>, <a href="/wiki/%D0%92%D0%BD%D1%83%D1%82%D1%80%D0%B8%D0%B2%D0%B5%D0%BD%D0%BD%D0%BE%D0%B5_%D0%B2%D0%BB%D0%B8%D0%B2%D0%B0%D0%BD%D0%B8%D0%B5" title="Внутривенное вливание">внутривенная инфузия</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Примечания"><span id=".D0.9F.D1.80.D0.B8.D0.BC.D0.B5.D1.87.D0.B0.D0.BD.D0.B8.D1.8F"></span>Примечания</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;veaction=edit&amp;section=5" title="Редактировать раздел «Примечания»" class="mw-editsection-visualeditor"><span>править</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;action=edit&amp;section=5" title="Редактировать код раздела «Примечания»"><span>править код</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist columns" style="list-style-type: decimal;"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text"><span class="citation"><span lang="en"><a rel="nofollow" class="external text" href="https://www.fda.gov/drugs/nda-and-bla-approvals/new-molecular-entity-nme-drug-and-new-biologic-approvals">CDER New Molecular Entity (NME) and Biologic Approvals Calendar Year 2011</a></span>&#160;<span class="ref-info" style="cursor:help;" title="на английском языке">(англ.)</span>.&#32;<a href="/wiki/FDA" class="mw-redirect" title="FDA">FDA</a>.&#32;Дата обращения: 21 февраля 2021.&#32;<a rel="nofollow" class="external text" href="https://web.archive.org/web/20210929205356/https://www.fda.gov/drugs/nda-and-bla-approvals/new-molecular-entity-nme-drug-and-new-biologic-approvals">Архивировано</a> 29 сентября 2021 года.</span></span> </li> <li id="cite_note-dailymed-2"><span class="mw-cite-backlink">↑ <a href="#cite_ref-dailymed_2-0"><sup><i><b>1</b></i></sup></a> <a href="#cite_ref-dailymed_2-1"><sup><i><b>2</b></i></sup></a></span> <span class="reference-text"><span class="citation" id="CITEREFDailyMed"><span lang="en"><a rel="nofollow" class="external text" href="https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2fa3c528-1777-4628-8a55-a69dae2381a3">BENLYSTA- belimumab injection, powder, lyophilized, for solution BENLYSTA- belimumab solution</a></span>&#160;<span class="ref-info" style="cursor:help;" title="на английском языке">(англ.)</span>.&#32;<i><a href="/wiki/DailyMed" title="DailyMed">DailyMed</a></i>.&#32;U. S. National Library of Medicine.</span></span> </li> </ol></div></div> <style data-mw-deduplicate="TemplateStyles:r137874932">.mw-parser-output .ambox{border:1px solid var(--border-color-base,#a2a9b1);border-left:10px solid #36c;background:var(--background-color-neutral-subtle,#f8f9fa);box-sizing:border-box;margin:0 10%}html body.mediawiki.skin-minerva .mw-parser-output .ambox{border-width:0 0 0 4px}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output .ambox+link+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+style+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+link+.ambox{margin-top:-1px}html body.mediawiki .mw-parser-output .ambox.mbox-small-left{margin:4px 1em 4px 0;overflow:hidden;width:238px;border-collapse:collapse;font-size:88%;line-height:1.25em}.mw-parser-output .ambox-speedy{border-left:10px solid var(--border-color-error,#b32424);background-color:var(--background-color-error-subtle,#fee7e6)}.mw-parser-output .ambox-delete{border-left:10px solid var(--border-color-error,#b32424)}.mw-parser-output .ambox-content{border-left:10px solid #f28500}.mw-parser-output .ambox-style{border-left:10px solid var(--color-warning,#edab00)}.mw-parser-output .ambox-good{border-left:10px solid #66cc44}.mw-parser-output .ambox-discussion{border-left:10px solid #339966}.mw-parser-output .ambox-merge{border-left:10px solid #9932cc}.mw-parser-output .ambox-move{border-left:10px solid #9932cc}.mw-parser-output .ambox-protection{border-left:10px solid #a2a9b1}.mw-parser-output .ambox .mbox-text{border:none;padding:0.25em 0.5em;width:100%}.mw-parser-output .ambox .mbox-image{border:none;padding:2px 0 2px 0.5em;text-align:center}.mw-parser-output .ambox .mbox-imageright{border:none;padding:2px 0.5em 2px 0;text-align:center}.mw-parser-output .ambox .mbox-empty-cell{border:none;padding:0;width:1px}.mw-parser-output .ambox .mbox-image-div{width:52px}.mw-parser-output .ambox .mbox-textsmall-div{font-size:90%}html.client-js body.skin-minerva .mw-parser-output .mbox-text-span{margin-left:23px!important}@media(max-width:1366px){.mw-parser-output .ambox{margin-left:6%;margin-right:6%}}@media(max-width:719px){.mw-parser-output .ambox{margin-left:0;margin-right:0}}</style><table class="mbox-Stub-meta plainlinks metadata ambox ambox-style" role="presentation" style="border:0; background:none; color:inherit; margin:0; font-style:italic;"><tbody><tr><td class="mbox-image"><div style="width:52px"><span typeof="mw:File"><a href="/wiki/%D0%A4%D0%B0%D0%B9%D0%BB:Noto_Emoji_KitKat_1f48a.svg" class="mw-file-description"><img alt="Таблетки" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Noto_Emoji_KitKat_1f48a.svg/30px-Noto_Emoji_KitKat_1f48a.svg.png" decoding="async" width="30" height="30" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/43/Noto_Emoji_KitKat_1f48a.svg/45px-Noto_Emoji_KitKat_1f48a.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/43/Noto_Emoji_KitKat_1f48a.svg/60px-Noto_Emoji_KitKat_1f48a.svg.png 2x" data-file-width="128" data-file-height="128" /></a></span></div></td><td class="mbox-text"><div class="mbox-text-div">Это <a href="/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%8F:%D0%97%D0%B0%D0%B3%D0%BE%D1%82%D0%BE%D0%B2%D0%BA%D0%B0_%D1%81%D1%82%D0%B0%D1%82%D1%8C%D0%B8" title="Википедия:Заготовка статьи">заготовка статьи</a>&#32;по <a href="/wiki/%D0%A4%D0%B0%D1%80%D0%BC%D0%B0%D0%BA%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D1%8F" title="Фармакология">фармакологии</a>. Помогите Википедии, дополнив её.</div><div class="mbox-textsmall-div hide-when-compact"></div></td></tr></tbody></table></div><!--esi <esi:include src="/esitest-fa8a495983347898/content" /> --><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&amp;useformat=desktop" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Источник — <a dir="ltr" href="https://ru.wikipedia.org/wiki/Белимумаб">https://ru.wikipedia.org/wiki/Белимумаб</a></div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/%D0%A1%D0%BB%D1%83%D0%B6%D0%B5%D0%B1%D0%BD%D0%B0%D1%8F:%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D0%B8" title="Служебная:Категории">Категории</a>: <ul><li><a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%8F:%D0%9B%D0%B5%D0%BA%D0%B0%D1%80%D1%81%D1%82%D0%B2%D0%B5%D0%BD%D0%BD%D1%8B%D0%B5_%D1%81%D1%80%D0%B5%D0%B4%D1%81%D1%82%D0%B2%D0%B0_%D0%BF%D0%BE_%D0%B0%D0%BB%D1%84%D0%B0%D0%B2%D0%B8%D1%82%D1%83" title="Категория:Лекарственные средства по алфавиту">Лекарственные средства по алфавиту</a></li><li><a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%8F:%D0%9C%D0%BE%D0%BD%D0%BE%D0%BA%D0%BB%D0%BE%D0%BD%D0%B0%D0%BB%D1%8C%D0%BD%D1%8B%D0%B5_%D0%B0%D0%BD%D1%82%D0%B8%D1%82%D0%B5%D0%BB%D0%B0" title="Категория:Моноклональные антитела">Моноклональные антитела</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Скрытая категория: <ul><li><a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%8F:%D0%9D%D0%B5%D0%B7%D0%B0%D0%B2%D0%B5%D1%80%D1%88%D1%91%D0%BD%D0%BD%D1%8B%D0%B5_%D1%81%D1%82%D0%B0%D1%82%D1%8C%D0%B8_%D0%BF%D0%BE_%D1%84%D0%B0%D1%80%D0%BC%D0%B0%D0%BA%D0%BE%D0%BB%D0%BE%D0%B3%D0%B8%D0%B8" title="Категория:Незавершённые статьи по фармакологии">Незавершённые статьи по фармакологии</a></li></ul></div></div> </div> </div> <div id="mw-navigation"> <h2>Навигация</h2> <div id="mw-head"> <nav id="p-personal" class="mw-portlet mw-portlet-personal vector-user-menu-legacy vector-menu" aria-labelledby="p-personal-label" > <h3 id="p-personal-label" class="vector-menu-heading " > <span class="vector-menu-heading-label">Персональные инструменты</span> </h3> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anonuserpage" class="mw-list-item"><span title="Страница участника для моего IP">Вы не представились системе</span></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%D0%A1%D0%BB%D1%83%D0%B6%D0%B5%D0%B1%D0%BD%D0%B0%D1%8F:%D0%9C%D0%BE%D1%91_%D0%BE%D0%B1%D1%81%D1%83%D0%B6%D0%B4%D0%B5%D0%BD%D0%B8%D0%B5" title="Страница обсуждений для моего IP [n]" accesskey="n"><span>Обсуждение</span></a></li><li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/%D0%A1%D0%BB%D1%83%D0%B6%D0%B5%D0%B1%D0%BD%D0%B0%D1%8F:%D0%9C%D0%BE%D0%B9_%D0%B2%D0%BA%D0%BB%D0%B0%D0%B4" title="Список правок, сделанных с этого IP-адреса [y]" accesskey="y"><span>Вклад</span></a></li><li id="pt-createaccount" class="mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BB%D1%83%D0%B6%D0%B5%D0%B1%D0%BD%D0%B0%D1%8F:%D0%A1%D0%BE%D0%B7%D0%B4%D0%B0%D1%82%D1%8C_%D1%83%D1%87%D1%91%D1%82%D0%BD%D1%83%D1%8E_%D0%B7%D0%B0%D0%BF%D0%B8%D1%81%D1%8C&amp;returnto=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1" title="Мы предлагаем вам создать учётную запись и войти в систему, хотя это и не обязательно."><span>Создать учётную запись</span></a></li><li id="pt-login" class="mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BB%D1%83%D0%B6%D0%B5%D0%B1%D0%BD%D0%B0%D1%8F:%D0%92%D1%85%D0%BE%D0%B4&amp;returnto=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1" title="Здесь можно зарегистрироваться в системе, но это необязательно. 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class="mw-list-item"><a href="/w/index.php?title=%D0%91%D0%B5%D0%BB%D0%B8%D0%BC%D1%83%D0%BC%D0%B0%D0%B1&amp;printable=yes" title="Версия этой страницы для печати [p]" accesskey="p"><span>Версия для печати</span></a></li> </ul> </div> </nav> <nav id="p-wikibase-otherprojects" class="mw-portlet mw-portlet-wikibase-otherprojects vector-menu-portal portal vector-menu" aria-labelledby="p-wikibase-otherprojects-label" > <h3 id="p-wikibase-otherprojects-label" class="vector-menu-heading " > <span class="vector-menu-heading-label">В других проектах</span> </h3> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Belimumab" hreflang="en"><span>Викисклад</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q1996249" title="Ссылка на связанный элемент репозитория данных [g]" accesskey="g"><span>Элемент Викиданных</span></a></li> </ul> </div> </nav> <nav id="p-lang" class="mw-portlet mw-portlet-lang vector-menu-portal portal vector-menu" aria-labelledby="p-lang-label" > <h3 id="p-lang-label" class="vector-menu-heading " > <span class="vector-menu-heading-label">На других языках</span> </h3> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A8%D9%8A%D9%84%D9%8A%D9%85%D9%88%D9%85%D8%A7%D8%A8" title="بيليموماب — арабский" lang="ar" hreflang="ar" data-title="بيليموماب" data-language-autonym="العربية" data-language-local-name="арабский" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D8%A8%D9%84%DB%8C%D9%85%D9%88%D9%85%D8%A7%D8%A8" title="بلیموماب — South Azerbaijani" lang="azb" hreflang="azb" data-title="بلیموماب" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Belimumab" title="Belimumab — каталанский" lang="ca" hreflang="ca" data-title="Belimumab" data-language-autonym="Català" data-language-local-name="каталанский" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Belimumab" title="Belimumab — немецкий" lang="de" hreflang="de" data-title="Belimumab" data-language-autonym="Deutsch" data-language-local-name="немецкий" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Belimumab" title="Belimumab — английский" lang="en" hreflang="en" data-title="Belimumab" data-language-autonym="English" data-language-local-name="английский" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Belimumabo" title="Belimumabo — эсперанто" lang="eo" hreflang="eo" data-title="Belimumabo" data-language-autonym="Esperanto" data-language-local-name="эсперанто" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Belimumab" title="Belimumab — испанский" lang="es" hreflang="es" data-title="Belimumab" data-language-autonym="Español" data-language-local-name="испанский" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A8%D9%84%DB%8C%D9%85%D9%88%D9%85%D8%A7%D8%A8" title="بلیموماب — персидский" lang="fa" hreflang="fa" data-title="بلیموماب" data-language-autonym="فارسی" data-language-local-name="персидский" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Belimumab" title="Belimumab — французский" lang="fr" hreflang="fr" data-title="Belimumab" data-language-autonym="Français" data-language-local-name="французский" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Belimumab" title="Belimumab — итальянский" lang="it" hreflang="it" data-title="Belimumab" data-language-autonym="Italiano" data-language-local-name="итальянский" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%AC%E0%AD%87%E0%AC%B2%E0%AC%BF%E0%AC%AE%E0%AD%81%E0%AC%AE%E0%AC%BE%E0%AC%AC" title="ବେଲିମୁମାବ — ория" lang="or" hreflang="or" data-title="ବେଲିମୁମାବ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="ория" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Belimumab" title="Belimumab — польский" lang="pl" hreflang="pl" data-title="Belimumab" data-language-autonym="Polski" data-language-local-name="польский" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Belimumab" title="Belimumab — португальский" lang="pt" hreflang="pt" data-title="Belimumab" data-language-autonym="Português" data-language-local-name="португальский" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Belimumab" title="Belimumab — сербскохорватский" lang="sh" hreflang="sh" data-title="Belimumab" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="сербскохорватский" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Belimumab" title="Belimumab — сербский" lang="sr" hreflang="sr" data-title="Belimumab" data-language-autonym="Српски / srpski" data-language-local-name="сербский" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Belimumab" title="Belimumab — турецкий" lang="tr" hreflang="tr" data-title="Belimumab" data-language-autonym="Türkçe" data-language-local-name="турецкий" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Belimumab" title="Belimumab — вьетнамский" lang="vi" hreflang="vi" data-title="Belimumab" data-language-autonym="Tiếng Việt" data-language-local-name="вьетнамский" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q1996249#sitelinks-wikipedia" title="Править ссылки на другие языки" class="wbc-editpage">Править ссылки</a></span></div> </div> </nav> </div> </div> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-copyright">Текст доступен по <a rel="nofollow" class="external text" href="//creativecommons.org/licenses/by-sa/4.0/deed.ru">лицензии Creative Commons «С указанием авторства — С сохранением условий» (CC BY-SA)</a>; в отдельных случаях могут действовать дополнительные условия. <span class="noprint">Подробнее см. <a class="external text" href="https://foundation.wikimedia.org/wiki/Policy:Terms_of_Use/ru">Условия использования</a>.</span><br 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