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Drug Overviews - PubPharm
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class="subnav-link-text">Quiz</span></a></li></ul></div></div></nav><!--TYPO3SEARCH_begin--></div><main class="section-column maincontent-wrap" role="main"><div id="c80" class="frame frame-size-default frame-default frame-type-text frame-layout-default frame-background-none frame-no-backgroundimage frame-space-before-medium frame-space-after-none"><div class="frame-group-container"><div class="frame-group-inner"><div class="frame-container frame-container-default"><div class="frame-inner"><header class="frame-header"><h2 class="element-header "><a href="https://narrative.pubpharm.de/drug_overview/" target="_blank" rel="noreferrer"><span>Drug Overviews</span></a></h2></header><p>Direkt zum Tool Drug Overviews: <a href="http://www.narrative.pubpharm.de/drug_overview" target="_blank" rel="noreferrer">www.narrative.pubpharm.de/drug_overview</a></p><p>Der <a href="https://narrative.pubpharm.de/" target="_blank" rel="noreferrer">Narrative Service</a> erlaubt es einzelne Übersichten über Assoziationen eines Wirkstoffes bzw. einer bioaktiven Substanz zu erzeugen, z.B. <em>Welche Erkrankungen werden mit Eptinezumab behandelt?</em>. Möchte man nun wissen, in welchen z.B. Arzneiformen Eptinezumab verfügbar ist und eingesetzt werden kann, ist eine neue Anfrage im Narrativen Service notwendig.</p><p>Für genau eine solche „Übersicht“ wurde die Erweiterung <a href="https://narrative.pubpharm.de/drug_overview" target="_blank" rel="noreferrer">Drug Overviews</a> (ein Alleinstellungsmerkmal von PubPharm) entwickelt. Nutzer:innen können in diesem Service gezielt nach einem Wirkstoff suchen und erhalten (I) vorhandene Informationen aus der Fachdatenbank <a href="https://www.ebi.ac.uk/chembl/" target="_blank" rel="noreferrer">ChEMBL</a> (u.a. pkA- und logP-Werte, Molekülmasse, etc.) und (II) extrahierte Assoziationen aus Fachliteratur (u.a. Interaktionen mit anderen Wirkstoffen, Informationen zu Targets und Labormethoden sowie Indikationen und Arzneiformen).</p><p>Zur Einführung in die Drug Overviews steht <a href="https://www.youtube.com/watch?v=FRhTPdxojjA" target="_blank" rel="noreferrer">hier</a> ein Video-Tutorial zur Verfügung. Die <a href="https://www.pubpharm.de/en/info/pubpharm-help" target="_blank">PubPharm Hilfe</a> bietet weiterführende Informationen zu einer Suche mit den Drug Overviews.</p><p>Informationen zum jeweiligen Wirkstoff werden in den Drug Overviews auch in Netzwerkansichten visualisiert. Ein Video-Tutorial zur Einführung in dieses Feature kann <a href="https://www.youtube.com/watch?v=iLMelMXAXFw" target="_blank" rel="noreferrer">hier</a> abgerufen werden.</p><p>Technische Hintergrundinformationen zum Tool Drug Overviews finden Sie in dieser Publikation: <a href="https://link.springer.com/article/10.1007/s00799-023-00356-3" target="_blank" rel="noreferrer">10.1007/s00799-023-00356-3</a></p><p><a href="/de/info/informationsmaterial" target="_blank">Hier</a> finden Sie zudem weitere Informationsmaterialien zu allen PubPharm-Services.</p></div></div></div></div></div></main></div></div></div><!--TYPO3SEARCH_end--></div><footer id="page-footer" class="bp-page-footer"><section class="section footer-section footer-section-content"><div class="container"><div class="section-row"><div class="section-column footer-section-content-column footer-section-content-column-left"><div id="c20" class="frame frame-size-default frame-default frame-type-html frame-layout-default 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