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<section id="block-secondarymenuclpswitzerlandfrench" class="block block-block-content block-block-content31a4681c-4b24-4c43-b705-0dc6b5dae508 clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><ul class="clp-secondary-menu"><li><a data-colorbox-inline=".cta-header-secondary-menu-news">ACTUALITÉS</a></li> <li><a data-colorbox-inline=".cta-header-secondary-menu-clinical-trial">Essais cliniques</a></li> <li><a data-colorbox-inline=".cta-header-secondary-menu-investors">Investisseurs</a></li> <li><a data-colorbox-inline=".cta-header-secondary-menu-careers">Carrières</a></li> </ul><div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-news popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">REDIRECTION EN COURS</h2> <p class="text-align-center">Vous quittez le site www.alnylam.ch et allez être redirigé vers notre site international 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class="text-align-center">Vous quittez le site www.alnylam.ch et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</p> <p class="text-align-center"><a class="button-more text-center" href="https://investors.alnylam.com/">CONTINUER</a></p> </div> </div> <div class="popup-content" style="display:none; background:#fff; padding:opx;"> <div class="cta-header-secondary-menu-careers popup-content" style="display:none; background:#fff;"> <h2 class="text-align-center">REDIRECTION EN COURS</h2> <p class="text-align-center">Vous quittez le site www.alnylam.ch et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</p> <p class="text-align-center"><a class="button-more text-center" href="/careers/">CONTINUER</a></p> </div> </div> </div> </section> <section id="block-language-4" class="block block-block-content block-block-content5a7dc698-6efe-4c02-a3cd-adb2377d4faf clearfix"> <div class="field 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</div> </section> </div> </div> </div> </div> </div> </div> </header> <div id="maindiv" class="container-fluid"> <main id="midcontent-area" class="column main-content"> <div id="content"> <div class="region region-content"> <div data-drupal-messages-fallback class="hidden"></div> <article data-history-node-id="686" role="article" about="/alnylam-switzerland-french" class="clp full clearfix"> <div class="content"> <div class="field field--name-field-add-section field--type-entity-reference-revisions field--label-hidden field--items"> <div class="field--item"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1286 paragraph--view-mode--default"> <div class="paragraph paragraph--type--banner-with-text paragraph-id--1286 paragraph--view-mode--default"> <div id="simple-banner-with-text-wrapper" style="background: url(/sites/default/files/2022-05/CLP_header_slider_hero.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:1130px;margin:auto;"> <div class="upper-text"> <h2>À ceux qui déclarent que c’est « impossible , illusoire ou irréaliste, » nous répondons que nous</h2> <h1>Relevons Le Défi</h1> <p>Nous développons actuellement une nouvelle classe de médicaments appelés traitements ARNi qui, selon nous, peuvent potentiellement transformer la vie des personnes atteintes de maladies rares.</p> </div> </div> </div> <div class="mobile-upper-text"> <h2>À ceux qui déclarent que c’est « impossible , illusoire ou irréaliste, » nous répondons que nous</h2> <h1>Relevons Le Défi</h1> <p>Nous développons actuellement une nouvelle classe de médicaments appelés traitements ARNi qui, selon nous, peuvent potentiellement transformer la vie des personnes atteintes de maladies rares.</p> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-banner-overlay paragraph-id--1288 paragraph--view-mode--default"> <div id="clp-banner-overlay"> <div class="banner-text-wrapper" style="width:1130px; margin:auto;"> <div class="text-box"> <section> <h1 class="text-align-center"><strong>À L’AVANT-GARDE DU CHANGEMENT </strong></h1> <p class="text-align-center">Basés sur des données scientifiques récompensées d’un Prix Nobel, les traitements ARNi constituent une approche pour le traitement d’un large éventail de maladies graves et invalidantes. Alnylam conduit la transformation de l’ARN interférence (ARNi) en une nouvelle classe de médicaments destinés à des patients disposant d’options de traitement limitées ou inadaptées.</p> <p class="text-align-center">Créée en 2002, la société Alnylam concrétise une vision audacieuse selon laquelle des possibilités scientifiques peuvent devenir une réalité en s’appuyant sur une solide plateforme de découverte et un large portefeuille de médicaments expérimentaux, dont cinq produits ayant atteint un stade avancé de développement et quattre produits approuvés aux États-Unis par la FDA, dans l'Union Européenne par l'EMA et en Suisse par Swissmedic.</p> </section> <div class="counter-box"> <h3 class="text-center"> </h3> <div class="row"> <div class="col-sm-2"> <h1 class="text-align-center">><span>1k</span></h1> <p class="count-text text-align-center">Employés</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>19</span></h1> <p class="count-text text-align-center">Pays</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>11</span></h1> <p class="count-text text-align-center">Programmes ayant actuellement atteint le stade de développement clinique</p> </div> <div class="col-sm-2"> <h1 class="text-align-center"><span>4</span></h1> <p class="count-text text-align-center">Produits approuvés</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>35</span></h1> <p class="count-text text-align-center">Études cliniques à ce jour</p> </div> <div class="col-sm-2"> <h1 class="text-align-center">><span>8</span></h1> <p class="count-text text-align-center">Ans durée d’exposition la plus longue</p> </div> </div> <p class="text-center margin-top-24px"><em>mise à jour en Avril 2022</em></p> </div> </div> </div> <div class=" popup-content" style="display:none; background:#fff;"> <div class="field field--name-field-pop-up-field field--type-entity-reference-revisions field--label-hidden field--item"> <div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1290 paragraph--view-mode--default"> <div class="paragraph paragraph--type--clp-full-bleed-bg paragraph-id--1290 paragraph--view-mode--default"> <div id="clp-full-bleed-bg" style="background: url(/sites/default/files/2022-01/bleed_0.jpg); background-size: cover; background-repeat: no-repeat;"> <div class="text-wrapper" style="width:900px;margin:auto;"> <h1 class="text-align-center"><strong>ARNi: UNE INNOVATION DANS LE DOMAINE DE LA BIOLOGIE qui s’appuie sur des recherches récompensées par un Prix Nobel</strong></h1> <p class="text-align-center">L’ARN interférence (ARNi) constitue une percée dans la compréhension de la façon dont les gènes sont régulés dans les cellules. C’est également une approche totalement nouvelle appliquée à la découverte et au développement de médicaments. Le Prix Nobel 2006 de physiologie ou de médecine, décerné à Craig Mello et Andrew Fire, a reconnu l’importance de l’ARNi comme une découverte scientifique majeure.</p> <p class="text-align-center"><a data-colorbox-inline=".cta-full-bleed-switzerland-french">En savoir plus ›</a></p> </div> <div class="cta-full-bleed-switzerland-french popup-content" style="display:none; background:#fff; overflow:hidden;"> <div class="field field--name-field-pop-up-content field--type-entity-reference-revisions field--label-hidden field--item"> <div> <h2 class="text-center">REDIRECTION EN COURS</h2> <h4>Vous quittez le site www.alnylam.ch et allez être redirigé vers notre site international (www.alnylam.com) dont le contenu est en anglais.</h4> <p class="text-center"> <a class="button-more" href="/our-science/the-science-of-rnai" target= "_blank">CONTINUER</a> </p> </div> </div> </div> </div> </div> </div> </div> <div class="field--item"> <div class="paragraph paragraph--type--clp-html-background paragraph-id--1297 paragraph--view-mode--default"> <div id="clp-html-content-background" style="background-color:#f8f8f8;"> <div class="content-wrapper" style="width:1130px; margin:auto; "> <div class="clp-html-background-desc"> <h2 class="text-align-center"><strong>Notre Priorité</strong></h2> <p class="text-align-center">L’ensemble de nos traitements RNAi expérimentaux visent à traiter des maladies dont les besoins médicaux ne sont pas satisfaits et qui s’inscrivent dans le cadre de 4 domaines thérapeutiques stratégiques (STArs, Strategic Therapeutic Areas): maladies génétiques, maladies cardio-métaboliques, maladies hépatiques infectieuses et maladies du système nerveux central (SNC) et oculaires.</p> <p class="text-align-center">Nos produits approuvés à l’intention des patients en Suisse traitent les neuropathies amyloïdes héréditaires (NAH) à transthyrétine (TTR), l’hyperoxalurie primitive de type 1 (HP1) et porphyrie hépatique aiguë (PHA). 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