CINXE.COM
Cardiovascular CRO for Clinical Trials
<!DOCTYPE html> <html lang="en" dir="ltr" prefix="content: http://purl.org/rss/1.0/modules/content/ dc: http://purl.org/dc/terms/ foaf: http://xmlns.com/foaf/0.1/ og: http://ogp.me/ns# rdfs: http://www.w3.org/2000/01/rdf-schema# schema: http://schema.org/ sioc: http://rdfs.org/sioc/ns# sioct: http://rdfs.org/sioc/types# skos: http://www.w3.org/2004/02/skos/core# xsd: http://www.w3.org/2001/XMLSchema# "> <head> <meta charset="utf-8" /> <style id="gutenberg-palette">:root .has-orange-color{color:#EB3300}:root .has-orange-background-color{background-color:#EB3300}:root .has-gold-color{color:#FF9E1B}:root .has-gold-background-color{background-color:#FF9E1B}:root .has-dark-gray-color{color:#63666A}:root .has-dark-gray-background-color{background-color:#63666A}:root .has-light-gray-color{color:#BBBCBC}:root .has-light-gray-background-color{background-color:#BBBCBC}:root .has-light-gray-2-color{color:#D8D8D8}:root .has-light-gray-2-background-color{background-color:#D8D8D8}:root .has-light-gray-3-color{color:#FAF9F9}:root .has-light-gray-3-background-color{background-color:#FAF9F9}:root .has-light-orange-color{color:#FF671F}:root .has-light-orange-background-color{background-color:#FF671F}:root .has-navy-color{color:#002E5D}:root .has-navy-background-color{background-color:#002E5D}:root .has-dark-red-color{color:#A6192E}:root .has-dark-red-background-color{background-color:#A6192E}:root .has-blue-color{color:#0076A5}:root .has-blue-background-color{background-color:#0076A5}:root .has-white-color{color:#FFFFFF}:root .has-white-background-color{background-color:#FFFFFF}:root .has-black-color{color:#000000}:root .has-black-background-color{background-color:#000000}</style> <meta name="description" content="Syneos Health Cardiovascular global CRO team is focused on cardiology, offering flexible, creative approaches to meeting complex product development challenges." /> <meta name="abstract" content="Syneos Health Cardiovascular global CRO team is focused on cardiology, offering flexible, creative approaches to meeting complex product development challenges." /> <meta name="robots" content="index, follow" /> <link rel="canonical" href="https://www.syneoshealth.com/therapeutic-depth/cardiovascular" /> <meta name="google-site-verification" content="W7E6EckWyGJyvHLnYDszXNQotSRjEQrAgpUoFw4aqCQ" /> <meta name="Generator" content="Drupal 9 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no" /> <script type="application/ld+json">{ "@context": "https://schema.org", "@graph": [ { "@type": "WebPage", "@id": "webpage", "author": { "@type": "Organization", "@id": "Syneos Health", "name": "Syneos Health", "url": "https://www.syneoshealth.com", "logo": { "@type": "ImageObject", "url": "https://www.syneoshealth.com/themes/custom/bootstrap_syneos_sass/logo.svg" } } }, { "@type": "WebSite", "@id": "syneoshealth.com", "name": "Syneos Health", "url": "https://www.syneoshealth.com", "publisher": { "@type": "MedicalOrganization", "@id": "syneoshealth.com", "name": "Syneos Health", "url": "https://www.syneoshealth.com", "logo": { "@type": "ImageObject", "url": "https://www.syneoshealth.com/themes/custom/bootstrap_syneos_sass/logo.svg" } } } ] }</script> <meta http-equiv="x-ua-compatible" content="ie=edge" /><script type="text/javascript">(window.NREUM||(NREUM={})).init={privacy:{cookies_enabled:true},ajax:{deny_list:["bam.nr-data.net"]},distributed_tracing:{enabled:true}};(window.NREUM||(NREUM={})).loader_config={agentID:"1588831357",accountID:"3185927",trustKey:"3185927",xpid:"VwcPVF9RDxABUVZRAgQPXlEI",licenseKey:"NRJS-aaae99226ce3b76ac6a",applicationID:"1573558859"};;/*! For license information please see nr-loader-spa-1.273.1.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>u});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function u(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>h,gD:()=>g,xN:()=>p});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const u="[data-nr-mask]",d=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(u):""===t||null===t?e.mask_selector=u:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function p(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,d());const r=(0,s.nY)(e);r&&(r.init=l[e])}function g(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=>{"use strict";r.d(t,{a:()=>c,o:()=>s});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error("All loader-config objects require an agent identifier!");if(!a[e])throw new Error("LoaderConfig for ".concat(e," was never set"));return a[e]}function c(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.loader_config=a[e])}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},u={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},d={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!d[e])throw new Error("Runtime for ".concat(e," was never set"));return d[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");d[e]={...(0,n.a)(t,u),...c},Object.hasOwnProperty.call(d[e],"harvestCount")||Object.defineProperty(d[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=d[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,Yq:()=>a,xv:()=>n});const n="1.273.1",i="PROD",o="CDN",a="2.0.0-alpha.12"},6154:(e,t,r)=>{"use strict";r.d(t,{A4:()=>s,OF:()=>d,RI:()=>i,WN:()=>h,bv:()=>o,gm:()=>a,lR:()=>f,m:()=>u,mw:()=>c,sb:()=>l});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s="complete"===a?.document?.readyState,c=Boolean("hidden"===a?.document?.visibilityState),u=""+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),l=d&&"undefined"==typeof SharedWorker,f=(()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);return Array.isArray(e)&&e.length>=2?+e[1]:0})(),h=Date.now()-(0,n.t)()},7295:(e,t,r)=>{"use strict";r.d(t,{Xv:()=>a,gX:()=>i,iW:()=>o});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t<n.length;t++){var r=n[t];if("*"===r.hostname)return!1;if(s(r.hostname,e.hostname)&&c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e&&e.length)for(var t=0;t<e.length;t++){let r=e[t];if(!r)continue;0===r.indexOf("http://")?r=r.substring(7):0===r.indexOf("https://")&&(r=r.substring(8));const i=r.indexOf("/");let o,a;i>0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a="");let[s]=o.split(":");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length>t.length)&&t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf("/")&&(e=e.substring(1)),0===t.indexOf("/")&&(t=t.substring(1)),""===e||e===t}},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>u});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};d(e),s[e].get(t)||s[e].set(t,r)}function u(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),h(e,t,!1),s[e].size&&f(e))}function d(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(d(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)p(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function p(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>u});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),u=function e(t,r){var n={},s={},d={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:p,addEventListener:p,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(u.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=h(n),c=g(e),d=c.length,l=0;l<d;l++)c[l].apply(a,r);var p=v()[s[e]];p&&p.push([f,e,r,a]);return a},get:m,listeners:g,context:h,buffer:function(e,t){const r=v();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function h(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function p(e,t){n[e]=g(e).concat(t)}function g(e){return n[e]||[]}function m(t){return d[t]=d[t]||e(f,t)}function v(){return f.backlog}}(void 0,"globalEE"),d=(0,n.Zm)();d.ee||(d.ee=u)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,ZF:()=>c,bz:()=>a,el:()=>u});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}function c(){return s(16)}function u(){return s(32)}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>u,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},u={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},7485:(e,t,r)=>{"use strict";r.d(t,{D:()=>i});var n=r(6154);function i(e){if(0===(e||"").indexOf("data:"))return{protocol:"data"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(":")),sameOrigin:t.protocol===n.gm?.location?.protocol&&t.host===n.gm?.location?.host};return r.port&&""!==r.port||("http:"===t.protocol&&(r.port="80"),"https:"===t.protocol&&(r.port="443")),r.pathname&&""!==r.pathname?r.pathname.startsWith("/")||(r.pathname="/".concat(r.pathname)):r.pathname="/",r}catch(e){return{}}}},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},3304:(e,t,r)=>{"use strict";r.d(t,{A:()=>o});var n=r(7836);const i=()=>{const e=new WeakSet;return(t,r)=>{if("object"==typeof r&&null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??""}catch(e){try{n.ee.emit("internal-error",[e])}catch(e){}return""}}},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>d,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>u,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function u(e){let t=a();return t.initializedAgents?.[e]}function d(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=>{"use strict";r.d(t,{u:()=>f});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,u="addEventListener",d="removeEventListener",l="nr@wrapped:".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get("events")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[u,d],"-",p)}function p(e,t){return e[1]}return"getPrototypeOf"in Object&&(a.RI&&h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(u+"-start",(function(e,t){var n=e[1];if(null!==n&&("function"==typeof n||"object"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if("function"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,"fn-",null,e.name||"anonymous"):n}));this.wrapped=e[1]=i}})),t.on(d+"-start",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;"object"==typeof n&&!Object.prototype.hasOwnProperty.call(n,u);)n=Object.getPrototypeOf(n);n&&t(n,...r)}},3434:(e,t,r)=>{"use strict";r.d(t,{Jt:()=>o,YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],u=e[c];d(u)||(e[c]=r(u,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return d(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){u([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,d,l;try{a=this,o=[...arguments],d="function"==typeof n?n(o,a):n||{}}catch(t){u([t,"",[o,a,s],d],e)}i(r+"start",[o,a,s],d,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],d,c),e}finally{i(r+"end",[o,a,l],d,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){u([t,r,n,i],e)}s=a}}}function u(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function d(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},9300:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.ajax},3333:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,Zp:()=>i,mq:()=>s,nf:()=>a,qN:()=>o});const n=r(860).K7.genericEvents,i=["auxclick","click","copy","keydown","paste","scrollend"],o=["focus","blur"],a=4,s=1e3},6774:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.jserrors},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,TZ:()=>a,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log",a=n.K7.logging},3785:(e,t,r)=>{"use strict";r.d(t,{R:()=>c,b:()=>u});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,["API/logging/".concat(c.toLowerCase(),"/called")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function u(e){return"string"==typeof e&&Object.values(s.p_).some((t=>t===e.toUpperCase().trim()))}},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{BB:()=>d,G4:()=>o,Qb:()=>l,TZ:()=>i,Ug:()=>a,_s:()=>s,bc:()=>u,yP:()=>c});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},u={RESET:{message:"Session was reset",sm:"Reset"},IMPORT:{message:"Recorder failed to import",sm:"Import"},TOO_MANY:{message:"429: Too Many Requests",sm:"Too-Many"},TOO_BIG:{message:"Payload was too large",sm:"Too-Big"},CROSS_TAB:{message:"Session Entity was set to OFF on another tab",sm:"Cross-Tab"},ENTITLEMENTS:{message:"Session Replay is not allowed and will not be started",sm:"Entitlement"}},d=5e3,l={API:"api"}},5270:(e,t,r)=>{"use strict";r.d(t,{Aw:()=>c,CT:()=>u,SR:()=>s});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO&&(0,o.V)(e)&&!0===(0,i.gD)(e,"session_trace.enabled")}function c(e){return!0===(0,i.gD)(e,"session_replay.preload")&&s(e)}function u(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=>{"use strict";r.d(t,{He:()=>i,Kp:()=>s,Lc:()=>u,Rz:()=>d,TZ:()=>n,bD:()=>o,d3:()=>a,jx:()=>l,uP:()=>c});const n=r(860).K7.sessionTrace,i="bstResource",o="resource",a="-start",s="-end",c="fn"+a,u="fn"+s,d="pushState",l=1e3},3962:(e,t,r)=>{"use strict";r.d(t,{AM:()=>o,O2:()=>s,Qu:()=>c,TZ:()=>a,ih:()=>u,tC:()=>i});var n=r(860);const i=["click","keydown","submit"],o="api",a=n.K7.softNav,s={INITIAL_PAGE_LOAD:"",ROUTE_CHANGE:1,UNSPECIFIED:2},c={INTERACTION:1,AJAX:2,CUSTOM_END:3,CUSTOM_TRACER:4},u={IP:"in progress",FIN:"finished",CAN:"cancelled"}},7378:(e,t,r)=>{"use strict";r.d(t,{$p:()=>x,BR:()=>b,Kp:()=>R,L3:()=>y,Lc:()=>c,NC:()=>o,SG:()=>d,TZ:()=>i,U6:()=>p,UT:()=>m,d3:()=>w,dT:()=>f,e5:()=>A,gx:()=>v,l9:()=>l,oW:()=>h,op:()=>g,rw:()=>u,tH:()=>E,uP:()=>s,wW:()=>T,xq:()=>a});var n=r(384);const i=r(860).K7.spa,o=["click","submit","keypress","keydown","keyup","change"],a=999,s="fn-start",c="fn-end",u="cb-start",d="api-ixn-",l="remaining",f="interaction",h="spaNode",p="jsonpNode",g="fetch-start",m="fetch-done",v="fetch-body-",b="jsonp-end",y=(0,n.dV)().o.ST,w="-start",R="-end",x="-body",T="cb"+R,A="jsTime",E="fetch"},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=>{"use strict";r.d(t,{V:()=>o});var n=r(9417),i=r(6154);const o=e=>i.RI&&!0===(0,n.gD)(e,"privacy.cookies_enabled")},425:(e,t,r)=>{"use strict";r.d(t,{j:()=>j});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),u=r(5289),d=r(6154),l=r(944),f=r(3969),h=r(384),p=r(6344);const g=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",p.G4.RECORD,p.G4.PAUSE,"log","wrapLogger"],m=["setErrorHandler","finished","addToTrace","addRelease"];var v=r(1863),b=r(2614),y=r(993),w=r(3785),R=r(2646),x=r(3434);function T(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,x.YM)(i),a=new R.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function A(){const e=(0,h.pV)();g.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),N=r(5603),O=r(5284);const _=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let I=!1;function j(e,t={},g,R){let{init:x,info:j,loader_config:P,runtime:C={},exposed:k=!0}=t;C.loaderType=g;const L=(0,h.pV)();j||(x=L.init,j=L.info,P=L.loader_config),(0,S.xN)(e.agentIdentifier,x||{}),(0,N.a)(e.agentIdentifier,P||{}),j.jsAttributes??={},d.bv&&(j.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,j);const H=(0,S.D0)(e.agentIdentifier),D=[j.beacon,j.errorBeacon];I||(H.proxy.assets&&(_(H.proxy.assets),D.push(H.proxy.assets)),H.proxy.beacon&&D.push(H.proxy.beacon),A(),(0,h.US)("activatedFeatures",O.B),e.runSoftNavOverSpa&&=!0===H.soft_navigations.enabled&&H.feature_flags.includes("soft_nav")),C.denyList=[...H.ajax.deny_list||[],...H.ajax.block_internal?D:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,"api");const g={};var R=s.ee.get(e),x=R.get("tracer");E[e]=b.g.OFF,R.on(p.G4.REPLAY_RUNNING,(t=>{E[e]=t}));var A="api-",S=A+"ixn-";function N(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?"session":void 0)(t,r)}function O(){}g.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,R),(0,w.R)(R,e,t,r)},g.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,R),T(R,e,t,{customAttributes:r,level:i})},m.forEach((e=>{g[e]=I(A,e,!0,"api")})),g.addPageAction=I(A,"addPageAction",!0,n.K7.genericEvents),g.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,I(A,"setPageViewName",!0)()},g.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return N(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},g.setUserId=function(e){if("string"==typeof e||null===e)return N("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},g.setApplicationVersion=function(e){if("string"==typeof e||null===e)return N("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},g.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,R),R.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},g[p.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.RECORD,[],void 0,n.K7.sessionReplay,R)},g[p.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,R),(0,a.p)(p.G4.PAUSE,[],void 0,n.K7.sessionReplay,R)},g.interaction=function(e){return(new O).get("object"==typeof e?e:{})};const _=O.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,R),h||(0,a.p)(S+"tracer",[(0,v.t)(),e,r],i,n.K7.spa,R),function(){if(x.emit((o?"":"no-")+"fn-start",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw x.emit("fn-err",[arguments,this,t],r),t}finally{x.emit("fn-end",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,R),i&&(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,R),r?void 0:this}}function j(){r.e(478).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),R.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{_[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),g.setCurrentRouteName=h?I(S,"routeName",void 0,n.K7.softNav):I(A,"routeName",!0,n.K7.spa),g.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,R),(0,a.p)("err",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,R)},d.RI?(0,u.GG)((()=>j()),!0):j(),g}(e.agentIdentifier,R,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=k),I=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>({212:"nr-spa-compressor",249:"nr-spa-recorder",478:"nr-spa"}[e]+"-1.273.1.min.js"),i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.273.1.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var u=document.getElementsByTagName("script"),d=0;d<u.length;d++){var l=u[d];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={478:"sha512-02Ykcrpzl4JvQ46re8YJcnOVT3PxJCiTwfiL6aPZ2Ce7bZJInb/7qwgqIIAmR9aO9iwRgYvkoqf5ev3ruaVCuw==",249:"sha512-ocbOXB0TUR2dpjE3aDOxqG2Vwgm7dGpbh16ElRyIKdoOZ+hdWyLWTroPOXbKKDCIeuBxV/wqwP5GCsG4LcTIwg==",212:"sha512-h3ZE1xdptNoj1oit85fWuIlHnVTAxhnoiIExHWaR5ZLpsLLs6DWnff4Gxsay38jNSZqGVAjeuFpbPzwxzrAfjA=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var h=(t,n)=>{s.onerror=s.onload=null,clearTimeout(p);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},p=setTimeout(h.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={38:0,788:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,u=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);u<a.length;u++)o=a[u],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.273.1.PROD"]=self["webpackChunk:NRBA-1.273.1.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function u(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var d=i(425);var l=i(1687),f=i(4234),h=i(5289),p=i(6154),g=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,v.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(478).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(478).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(478).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};p.RI?(0,h.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,g.SR)(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class w extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var R=i(384);var x=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class N extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),p.RI&&((0,T.u)((()=>(0,x.p)("docHidden",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)("pagehide",(()=>(0,x.p)("winPagehide",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class _ extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),j=i(3304);class P{constructor(e,t,r,n,i){this.name="UncaughtError",this.message="string"==typeof e?e:(0,j.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return H(e)?e:new P(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t="Unhandled Promise Rejection";if(!e?.reason)return;if(H(e.reason))try{return e.reason.message=t+": "+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+": "+r?.message,r}function L(e){if(e.error instanceof SyntaxError&&!/:\d+$/.test(e.error.stack?.trim())){const t=new P(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return H(e.error)?e.error:C(e)}function H(e){return e instanceof Error&&!!e.stack}class D extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on("internal-error",(e=>{this.abortHandler&&(0,x.p)("ierr",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.#r=e})),p.gm.addEventListener("unhandledrejection",(e=>{this.abortHandler&&(0,x.p)("err",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),p.gm.addEventListener("error",(e=>{this.abortHandler&&(0,x.p)("err",[L(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var M=i(8990);let K=1;const U="nr@id";function V(e){const t=typeof e;return!e||"object"!==t&&"function"!==t?-1:e===p.gm?0:(0,M.I)(e,U,(function(){return K++}))}function G(e){if("string"==typeof e&&e.length)return e.length;if("object"==typeof e){if("undefined"!=typeof ArrayBuffer&&e instanceof ArrayBuffer&&e.byteLength)return e.byteLength;if("undefined"!=typeof Blob&&e instanceof Blob&&e.size)return e.size;if(!("undefined"!=typeof FormData&&e instanceof FormData))try{return(0,j.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=["open","send"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get("xhr")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=p.gm.XMLHttpRequest,a=p.gm.MutationObserver,s=p.gm.Promise,c=p.gm.setInterval,u="readystatechange",d=["onload","onerror","onabort","onloadstart","onloadend","onprogress","ontimeout"],l=[],f=p.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit("new-xhr",[r],a),r.addEventListener(u,(s=a,function(){var e=this;e.readyState>3&&!s.resolved&&(s.resolved=!0,n.emit("xhr-resolved",[],e)),i.inPlace(e,d,"fn-",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit("internal-error",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,["onreadystatechange"],"fn-",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,"-xhr-",y),n.on("send-xhr-start",(function(e,t){h(e,t),function(e){l.push(e),a&&(g?g.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on("open-xhr-start",h),a){var g=s&&s.resolve();if(!c&&!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on("fn-end",(function(e){e[0]&&e[0].type===u||b()}));function b(){for(var e=0;e<l.length;e++)h(0,l[e]);l.length&&(l=[])}function y(e,t){return t}return n}var Y="fetch-",X=Y+"body-",J=["arrayBuffer","blob","json","text","formData"],Q=p.gm.Request,ee=p.gm.Response,te="prototype";const re={};function ne(e){const t=function(e){return(e||B.ee).get("fetch")}(e);if(!(Q&&ee&&p.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];"function"==typeof i&&(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+"before-start",[r],o),o[B.P]&&o[B.P].dt&&(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+"start",[r,e],a),a.then((function(e){return t.emit(n+"end",[null,e],a),e}),(function(e){throw t.emit(n+"end",[e],a),e}))})}return re[t.debugId]=1,J.forEach((e=>{r(Q[te],e,X),r(ee[te],e,X)})),r(p.gm,"fetch",Y),t.on(Y+"end",(function(e,r){var n=this;if(r){var i=r.headers.get("content-length");null!==i&&(n.rxSize=i),t.emit(Y+"done",[null,r],n)}else t.emit(Y+"done",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||"").toString()||null,i=(t.agentID||"").toString()||null,o=(t.trustKey||"").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),u={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)&&this.useTraceContextHeadersForCors())&&(u.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),u.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin&&!this.excludeNewrelicHeader()||!e.sameOrigin&&this.isAllowedOrigin(e)&&this.useNewrelicHeaderForCors())&&(u.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),u}generateTraceContextParentHeader(e,t){return"00-"+t+"-"+e+"-01"}generateTraceContextStateHeader(e,t,r,n,i){return i+"@nr=0-1-"+r+"-"+n+"-"+e+"----"+t}generateTraceHeader(e,t,r,n,i,o){if(!("function"==typeof p.gm?.btoa))return null;var a={v:[0,1],d:{ty:"Browser",ac:n,ap:i,id:e,tr:t,ti:r}};return o&&n!==o&&(a.d.tk=o),btoa((0,j.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()&&this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,"distributed_tracing")&&(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n<r.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname&&e.protocol===i.protocol&&e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),ue=["load","error","abort","timeout"],de=ue.length,le=(0,R.dV)().o.REQ,fe=(0,R.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=>(0,x.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:"xhr",fetch:"fetch",beacon:"beacon"};p.gm?.performance?.getEntriesByType("resource").forEach((t=>{if(t.initiatorType in e&&0!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};pe(r,t.name),this.handler("xhr",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=R,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener("load",(function(r){T(t,e)}),(0,A.jT)(!1)),p.lR||e.addEventListener("progress",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},pe(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid&&this.sameOrigin&&r.setRequestHeader("X-NewRelic-ID",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader&&(r.setRequestHeader("newrelic",i.newrelicHeader),o=!0),i.traceContextParentHeader&&(r.setRequestHeader("traceparent",i.traceContextParentHeader),i.traceContextStateHeader&&r.setRequestHeader("tracestate",i.traceContextStateHeader),o=!0),o&&(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n&&i){var a=G(i);a&&(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{"abort"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),("load"!==e.type||o.called===o.totalCbs&&(o.onloadCalled||"function"!=typeof r.onload)&&"function"==typeof o.end)&&o.end(r)}catch(e){try{t.emit("internal-error",[e])}catch(e){}}};for(var s=0;s<de;s++)r.addEventListener(ue[s],this.listener,(0,A.jT)(!1))}function u(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled&&"function"==typeof r.onload||"function"!=typeof this.end||this.end(r)}function d(e,t){var r=""+V(e)+!!t;this.xhrGuids&&!this.xhrGuids[r]&&(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=""+V(e)+!!t;this.xhrGuids&&this.xhrGuids[r]&&(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-added",[e[1],e[2]],r)}function g(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-removed",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe&&("onload"===r&&(this.onload=!0),("load"===(e[0]&&e[0].type)||this.onload)&&(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart&&t.emit("xhr-cb-time",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if("string"==typeof e[0]?0===(t=e[0]).length&&p.RI&&(t=""+p.gm.location.href):e[0]&&e[0].url?t=e[0].url:p.gm?.URL&&e[0]&&e[0]instanceof URL?t=e[0].href:"function"==typeof e[0].toString&&(t=e[0].toString()),"string"==typeof t&&0!==t.length){t&&(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i&&(i.newrelicHeader||i.traceContextParentHeader))if(e[0]&&e[0].headers)s(e[0].headers,i)&&(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)&&(this.dt=i),e.length>1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader&&(e.set("newrelic",t.newrelicHeader),r=!0),t.traceContextParentHeader&&(e.set("traceparent",t.traceContextParentHeader),t.traceContextStateHeader&&e.set("tracestate",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length>=1&&(this.target=e[0]),e.length>=2&&(this.opts=e[1]);var r,n=this.opts||{},i=this.target;"string"==typeof i?r=i:"object"==typeof i&&i instanceof le?r=i.url:p.gm?.URL&&"object"==typeof i&&i instanceof URL&&(r=i.href),pe(this,r);var o=(""+(i&&i instanceof le&&i.method||n.method||"GET")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function w(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,"string"==typeof this.rxSize&&this.rxSize.length>0&&(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r("xhr",[this.params,i,this.startTime,this.endTime,"fetch"],this,a.K7.ajax)}function R(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t<de;t++)e.removeEventListener(ue[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status&&(t.status=0):T(this,e),n.cbTime=this.cbTime,r("xhr",[t,n,this.startTime,this.endTime,"xhr"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return"json"===r&&null!==t?t:"arraybuffer"===r||"blob"===r||"json"===r?G(e.response):"text"===r||""===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n&&(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader("X-NewRelic-App-Data");i&&((0,x.p)(O.rs,["Ajax/CrossApplicationTracing/Header/Seen"],void 0,a.K7.metrics,t),e.params.cat=i.split(", ").pop())}e.loadCaptureCalled=!0}t.on("new-xhr",i),t.on("open-xhr-start",o),t.on("open-xhr-end",s),t.on("send-xhr-start",c),t.on("xhr-cb-time",u),t.on("xhr-load-added",d),t.on("xhr-load-removed",l),t.on("xhr-resolved",f),t.on("addEventListener-end",h),t.on("removeEventListener-end",g),t.on("fn-end",v),t.on("fetch-before-start",b),t.on("fetch-start",y),t.on("fn-start",m),t.on("fetch-done",w)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function pe(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+":"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const ge={},me=["pushState","replaceState"];function ve(e){const t=function(e){return(e||B.ee).get("history")}(e);return!p.RI||ge[t.debugId]++||(ge[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,"-")),t}var be=i(3738);const{He:ye,bD:we,d3:Re,Kp:xe,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class Ne extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,x.p)("bst",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+Re,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+xe,(function(e){(0,x.p)("bstHist",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=>{const t=e.getEntries();(0,x.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:we,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class _e extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem("".concat(Oe.H3,"_").concat(Oe.uh)))}catch(e){}(0,g.SR)(e.agentIdentifier)&&this.ee.on(t.G4.RECORD,(()=>this.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on("err",(e=>{this.replayRunning&&(this.errorNoticed=!0,(0,x.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.replayRunning=e}))}#s(e){return e&&(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,g.Aw)(this.agentIdentifier)}#u=!1;async#c(e){if(!this.#u){this.#u=!0;try{const{Recorder:t}=await Promise.all([i.e(478),i.e(249)]).then(i.bind(i,2496));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL&&this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder&&this.recorder.parent.mode!==Oe.g.FULL&&(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3962);class je extends b{static featureName=Ie.TZ;constructor(e,t=!0){if(super(e,Ie.TZ,t),!p.RI||!(0,R.dV)().o.MO)return;const r=ve(this.ee);Ie.tC.forEach((e=>{(0,A.sp)(e,(e=>{a(e)}),!0)}));const n=()=>(0,x.p)("newURL",[(0,S.t)(),""+window.location],void 0,this.featureName,this.ee);r.on("pushState-end",n),r.on("replaceState-end",n);try{this.removeOnAbort=new AbortController}catch(e){}(0,A.sp)("popstate",(e=>(0,x.p)("newURL",[e.timeStamp,""+window.location],void 0,this.featureName,this.ee)),!0,this.removeOnAbort?.signal);let i=!1;const o=new((0,R.dV)().o.MO)(((e,t)=>{i||(i=!0,requestAnimationFrame((()=>{(0,x.p)("newDom",[(0,S.t)()],void 0,this.featureName,this.ee),i=!1})))})),a=(0,v.s)((e=>{(0,x.p)("newUIEvent",[e],void 0,this.featureName,this.ee),o.observe(document.body,{attributes:!0,childList:!0,subtree:!0,characterData:!0})}),100,{leading:!0});this.abortHandler=function(){this.removeOnAbort?.abort(),o.disconnect(),this.abortHandler=void 0},this.importAggregator(e,{domObserver:o})}}var Pe=i(7378);const Ce={},ke=["appendChild","insertBefore","replaceChild"];function Le(e){const t=function(e){return(e||B.ee).get("jsonp")}(e);if(!p.RI||Ce[t.debugId])return t;Ce[t.debugId]=!0;var r=(0,W.YM)(t),n=/[?&](?:callback|cb)=([^&#]+)/,i=/(.*)\.([^.]+)/,o=/^(\w+)(\.|$)(.*)$/;function a(e,t){if(!e)return t;const r=e.match(o),n=r[1];return a(r[3],t[n])}return r.inPlace(Node.prototype,ke,"dom-"),t.on("dom-start",(function(e){!function(e){if(!e||"string"!=typeof e.nodeName||"script"!==e.nodeName.toLowerCase())return;if("function"!=typeof e.addEventListener)return;var o=(s=e.src,c=s.match(n),c?c[1]:null);var s,c;if(!o)return;var u=function(e){var t=e.match(i);if(t&&t.length>=3)return{key:t[2],parent:a(t[1],window)};return{key:e,parent:window}}(o);if("function"!=typeof u.parent[u.key])return;var d={};function l(){t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}function f(){t.emit("jsonp-error",[],d),t.emit("jsonp-end",[],d),e.removeEventListener("load",l,(0,A.jT)(!1)),e.removeEventListener("error",f,(0,A.jT)(!1))}r.inPlace(u.parent,[u.key],"cb-",d),e.addEventListener("load",l,(0,A.jT)(!1)),e.addEventListener("error",f,(0,A.jT)(!1)),t.emit("new-jsonp",[e.src],d)}(e[0])})),t}const He={};function De(e){const t=function(e){return(e||B.ee).get("promise")}(e);if(He[t.debugId])return t;He[t.debugId]=!0;var r=t.context,n=(0,W.YM)(t),i=p.gm.Promise;return i&&function(){function e(r){var o=t.context(),a=n(r,"executor-",o,null,!1);const s=Reflect.construct(i,[a],e);return t.context(s).getCtx=function(){return o},s}p.gm.Promise=e,Object.defineProperty(e,"name",{value:"Promise"}),e.toString=function(){return i.toString()},Object.setPrototypeOf(e,i),["all","race"].forEach((function(r){const n=i[r];e[r]=function(e){let i=!1;[...e||[]].forEach((e=>{this.resolve(e).then(a("all"===r),a(!1))}));const o=n.apply(this,arguments);return o;function a(e){return function(){t.emit("propagate",[null,!i],o,!1,!1),i=i||!e}}}})),["resolve","reject"].forEach((function(r){const n=i[r];e[r]=function(e){const r=n.apply(this,arguments);return e!==r&&t.emit("propagate",[e,!0],r,!1,!1),r}})),e.prototype=i.prototype;const o=i.prototype.then;i.prototype.then=function(...e){var i=this,a=r(i);a.promise=i,e[0]=n(e[0],"cb-",a,null,!1),e[1]=n(e[1],"cb-",a,null,!1);const s=o.apply(this,e);return a.nextPromise=s,t.emit("propagate",[i,!0],s,!1,!1),s},i.prototype.then[W.Jt]=o,t.on("executor-start",(function(e){e[0]=n(e[0],"resolve-",this,null,!1),e[1]=n(e[1],"resolve-",this,null,!1)})),t.on("executor-err",(function(e,t,r){e[1](r)})),t.on("cb-end",(function(e,r,n){t.emit("propagate",[n,!0],this.nextPromise,!1,!1)})),t.on("propagate",(function(e,r,n){this.getCtx&&!r||(this.getCtx=function(){if(e instanceof Promise)var r=t.context(e);return r&&r.getCtx?r.getCtx():this})}))}(),t}const Me={},Ke="setTimeout",Ue="setInterval",Ve="clearTimeout",Ge="-start",Fe=[Ke,"setImmediate",Ue,Ve,"clearImmediate"];function Be(e){const t=function(e){return(e||B.ee).get("timer")}(e);if(Me[t.debugId]++)return t;Me[t.debugId]=1;var r=(0,W.YM)(t);return r.inPlace(p.gm,Fe.slice(0,2),Ke+"-"),r.inPlace(p.gm,Fe.slice(2,3),Ue+"-"),r.inPlace(p.gm,Fe.slice(3),Ve+"-"),t.on(Ue+Ge,(function(e,t,n){e[0]=r(e[0],"fn-",null,n)})),t.on(Ke+Ge,(function(e,t,n){this.method=n,this.timerDuration=isNaN(e[1])?0:+e[1],e[0]=r(e[0],"fn-",this,n)})),t}const We={};function ze(e){const t=function(e){return(e||B.ee).get("mutation")}(e);if(!p.RI||We[t.debugId])return t;We[t.debugId]=!0;var r=(0,W.YM)(t),n=p.gm.MutationObserver;return n&&(window.MutationObserver=function(e){return this instanceof n?new n(r(e,"fn-")):n.apply(this,arguments)},MutationObserver.prototype=n.prototype),t}const{TZ:qe,d3:Ze,Kp:Ye,$p:Xe,wW:Je,e5:Qe,tH:$e,uP:et,rw:tt,Lc:rt}=Pe;class nt extends b{static featureName=qe;constructor(e,t=!0){if(super(e,qe,t),!p.RI)return;try{this.removeOnAbort=new AbortController}catch(e){}let r,n=0;const i=this.ee.get("tracer"),o=Le(this.ee),a=De(this.ee),s=Be(this.ee),c=Z(this.ee),u=this.ee.get("events"),d=ne(this.ee),l=ve(this.ee),f=ze(this.ee);function h(e,t){l.emit("newURL",[""+window.location,t])}function g(){n++,r=window.location.hash,this[et]=(0,S.t)()}function m(){n--,window.location.hash!==r&&h(0,!0);var e=(0,S.t)();this[Qe]=~~this[Qe]+e-this[et],this[rt]=e}function v(e,t){e.on(t,(function(){this[t]=(0,S.t)()}))}this.ee.on(et,g),a.on(tt,g),o.on(tt,g),this.ee.on(rt,m),a.on(Je,m),o.on(Je,m),this.ee.on("fn-err",((...t)=>{t[2]?.__newrelic?.[e.agentIdentifier]||(0,x.p)("function-err",[...t],void 0,this.featureName,this.ee)})),this.ee.buffer([et,rt,"xhr-resolved"],this.featureName),u.buffer([et],this.featureName),s.buffer(["setTimeout"+Ye,"clearTimeout"+Ze,et],this.featureName),c.buffer([et,"new-xhr","send-xhr"+Ze],this.featureName),d.buffer([$e+Ze,$e+"-done",$e+Xe+Ze,$e+Xe+Ye],this.featureName),l.buffer(["newURL"],this.featureName),f.buffer([et],this.featureName),a.buffer(["propagate",tt,Je,"executor-err","resolve"+Ze],this.featureName),i.buffer([et,"no-"+et],this.featureName),o.buffer(["new-jsonp","cb-start","jsonp-error","jsonp-end"],this.featureName),v(d,$e+Ze),v(d,$e+"-done"),v(o,"new-jsonp"),v(o,"jsonp-end"),v(o,"cb-start"),l.on("pushState-end",h),l.on("replaceState-end",h),window.addEventListener("hashchange",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("load",h,(0,A.jT)(!0,this.removeOnAbort?.signal)),window.addEventListener("popstate",(function(){h(0,n>1)}),(0,A.jT)(!0,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var it=i(3333);class ot extends b{static featureName=it.TZ;constructor(e,t=!0){super(e,it.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];p.RI&&e.init.user_actions.enabled&&(it.Zp.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)),!0))),it.qN.forEach((e=>(0,A.sp)(e,(e=>(0,x.p)("ua",[e],void 0,this.featureName,this.ee)))))),r.some((e=>e))?this.importAggregator(e):this.deregisterDrain()}}var at=i(993),st=i(3785);class ct extends b{static featureName=at.TZ;constructor(e,t=!0){super(e,at.TZ,t);const r=this.ee;this.ee.on("wrap-logger-end",(function([e]){const{level:t,customAttributes:n}=this;(0,st.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),p.gm?(this.features={},(0,R.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(w),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,d.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=u(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,R.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[he,w,N,Ne,_e,_,D,ot,ct,je,nt],loaderType:"spa"})})()})();</script> <link rel="icon" href="/themes/custom/bootstrap_syneos_sass/favicon.ico" type="image/vnd.microsoft.icon" /> <script src="https://ecdn.syneoshealth.com/s3fs-public/google_tag/syneoshealth.com/google_tag.script.js?VersionId=OPRtFXasa1VL19kuiElO.VaKkhuokBe4?snlljb" defer></script> <script>window.a2a_config=window.a2a_config||{};a2a_config.callbacks=[];a2a_config.overlays=[];a2a_config.templates={};a2a_config.exclude_services = [ "facebook_messenger", "google_gmail", "amazon_wish_list", "aol_mail", "bitty_browser", "bookmarks_fr", "box_net", "copy_link", "diary_ru", "google_classroom", "hacker_news", "kindle_it", "mail_ru", "microsoft_teams", "outlook_com", "rediff", "sina_weibo", "symbaloo_bookmarks", "typepad_post", "yahoo_mail", "reddit", "whatsapp", "email", "pinterest", "telegram", "pocket", "tumblr", "balatarin", "bibsonomy", "blogger", "blogmarks", "buffer", "diaspora", "digg", "diigo", "douban", "draugiem", "evernote", "fark", "flipboard", "folkd", "hatena", "houzz", "instapaper", "kakao", "known", "line", "livejournal", "mastodon", "mendeley", "meneame", "mewe", "mixi", "myspace", "odnoklassniki", "papaly", "pinboard", "plurk", "print", "printfriendly", "pusha", "qzone", "refind", "sitejot", "skype", "slashdot", "sms", "snapchat", "stocktwits", "svejo", "threema", "trello", "twiddla", "viber", "vk", "wechat", "wordpress", "wykop", "xing", "yummly", "whatsapp", "email", "pinterest", "telegram", "pocket", "email" ];</script> <title>Cardiovascular CRO for Clinical Trials</title> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/ajax-progress.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/align.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/autocomplete-loading.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/fieldgroup.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/container-inline.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/clearfix.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/details.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/hidden.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/item-list.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/js.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/nowrap.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/position-container.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/progress.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/reset-appearance.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/resize.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/sticky-header.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/system-status-counter.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/system-status-report-counters.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/system-status-report-general-info.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/tabledrag.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/tablesort.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/core/modules/system/css/components/tree-child.module.css?snlljb" /> <link rel="stylesheet" media="all" href="/modules/custom/syneos_gutenberg_blocks/css/call-to-action.css?snlljb" /> <link rel="stylesheet" media="all" href="/modules/custom/syneos_gutenberg_blocks/css/card-image-panel.css?snlljb" /> <link rel="stylesheet" media="all" href="/modules/custom/syneos_gutenberg_blocks/css/two-column-highlight.css?snlljb" /> <link rel="stylesheet" media="all" href="/modules/contrib/addtoany/css/addtoany.css?snlljb" /> <link rel="stylesheet" media="all" href="/modules/contrib/gutenberg/vendor/gutenberg/block-library/style.css?snlljb" /> <link rel="stylesheet" media="all" href="/modules/contrib/gutenberg/vendor/gutenberg/block-library/theme.css?snlljb" /> <link rel="stylesheet" media="all" href="/modules/contrib/gutenberg/css/block-library.css?snlljb" id="drupal-blocks" /> <link rel="stylesheet" media="all" href="/themes/contrib/bootstrap_barrio/css/components/affix.css?snlljb" /> <link rel="stylesheet" media="all" href="/themes/custom/bootstrap_syneos_sass/css/style.min.css?snlljb" /> <link rel="stylesheet" media="all" href="/themes/custom/bootstrap_syneos_sass/css/bootstrap5-dropdown-ml-hack-hover.css?snlljb" /> <link rel="stylesheet" media="all" href="/themes/contrib/bootstrap_barrio/css/components/breadcrumb.css?snlljb" /> <link rel="stylesheet" media="all" href="/themes/contrib/bootstrap_barrio/css/colors/messages/messages-light.css?snlljb" /> <link rel="stylesheet" media="all" href="/themes/custom/bootstrap_syneos_sass/css/onelink.css?snlljb" /> </head> <body class="layout-no-sidebars has-featured-top page-node-1031 page--therapeutic-depth-cardiovascular path-node node--type-page"> <a href="#main-content" class="visually-hidden-focusable"> Skip to main content </a> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-KSJ933B" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div id="page-wrapper" class="container-fluid p-0"> <div id="page" class="position-relative"> <div id="menuoverlay"></div> <header id="header" class="header coantiner-fluid p-0" role="banner" aria-label="Site header"> <span class="close"></span> <nav class="navbar" id="navbar-top"> <div class="container"> <div class="form-inline navbar-form ms-auto"> <section class="row region region-top-header-form"> <nav role="navigation" aria-labelledby="block-secondarynavigation-menu" id="block-secondarynavigation" class="block block-menu navigation menu--secondary-navigation d-flex" aria-expanded="false"> <h2 class="visually-hidden" id="block-secondarynavigation-menu">Secondary navigation</h2> <ul class="clearfix nav"> <li class="nav-item menu-item--expanded"> <span class="nav-link nav-link-">News</span> <ul class="menu"> <li class="nav-item"> <a href="/news-releases" class="nav-link nav-link--news-releases" data-drupal-link-system-path="node/92">News Releases</a> </li> <li class="nav-item"> <a href="/news-site-partnerships" class="nav-link nav-link--news-site-partnerships" data-drupal-link-system-path="node/1842">Sites & Networks</a> </li> <li class="nav-item"> <a href="/news/in-the-news" class="nav-link nav-link--news-in-the-news" data-drupal-link-system-path="node/1350">In The News</a> </li> <li class="nav-item"> <a href="/media-contact" class="nav-link nav-link--media-contact" data-drupal-link-system-path="node/1351">Media Contact</a> </li> </ul> </li> <li class="nav-item"> <a href="/events" class="nav-link nav-link--events" data-drupal-link-system-path="node/1235">Events</a> </li> <li class="nav-item"> <a href="https://registration-studyengage.studykik.com/" target="_blank" class="nav-link nav-link-https--registration-studyengagestudykikcom-">Investigators</a> </li> <li class="nav-item"> <a href="/careers" class="nav-link nav-link--careers" data-drupal-link-system-path="node/1174">Careers</a> </li> <li class="nav-item"> <a href="/contact-us" class="nav-link nav-link--contact-us" data-drupal-link-system-path="node/1205">Contact Us</a> </li> </ul> <div class="dropdown me-4 me-md-0" id="language-dropdown-wrapper"> <div class="nav-link text-decoration-none" id="language-dropdown" data-bs-toggle="dropdown" aria-expanded="false"> <i class="bi bi-globe me-md-1"></i> <span class="d-none d-md-inline-block">English</span> <i class="bi bi-caret-down-fill ms-md-2"></i> </div> <ul class="dropdown-menu dropdown-menu-end" aria-labelledby="language-dropdown"> <li> <a class="dropdown-item en" href="https://syneoshealth.com">English</a> </li> <li> <a class="dropdown-item ca" href="https://ca.syneoshealth.com">Français Canadien</a> </li> <li> <a class="dropdown-item jp" href="https://jp.syneoshealth.com">日本語</a> </li> </ul> </div> </nav> </section> </div> </div> </nav> <nav class="navbar navbar-light bg-transparent navbar-expand-md" id="navbar-main"> <div class="container"> <a href="/" title="Home" rel="home" class="navbar-brand"> <img src="/themes/custom/bootstrap_syneos_sass/logo.svg" alt="Home" class="img-fluid d-inline-block align-top"/> </a> <button class="navbar-toggler collapsed" type="button" data-bs-toggle="collapse" data-bs-target="#CollapsingNavbar" aria-controls="CollapsingNavbar" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="collapse navbar-collapse justify-content-end" id="CollapsingNavbar"> <nav role="navigation" aria-labelledby="block-mainnavigation-2-menu" id="block-mainnavigation-2" class="block block-menu navigation menu--main position-relative"> <h2 class="visually-hidden" id="block-mainnavigation-2-menu">Main navigation</h2> <div class="row justify-content-end p-0 m-0 flex-column flex-lg-row"> <div class="col col-auto"> <ul class="nav navbar-nav lvl-0"> <li class="nav-item menu-item--expanded dropdown"> <a href="/who-we-are" title="Who We Are" class="nav-link drpdwn-toggle nav-link--who-we-are" data-drupal-link-system-path="node/1170">Who We Are</a> <a href="/who-we-are" title="Who We Are" class="overview nav-link" data-drupal-link-system-path="node/1170">Who We Are</a> <ul class="dropdown-menu lvl-1"> <li class="drpdwn-item"> <a href="/who-we-are/our-vision-and-values" class="nav-link--who-we-are-our-vision-and-values" data-drupal-link-system-path="node/1169">Our Vision and Values</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/who-we-are/our-leadership" class="nav-link--who-we-are-our-leadership" data-drupal-link-system-path="node/1496">Our Leadership</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/who-we-are/environmental-social-and-governance-esg" class="nav-link--who-we-are-environmental-social-and-governance-esg" data-drupal-link-system-path="node/1513">Environmental, Social & Governance (ESG)</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <a href="/who-we-are/diversity-equity-inclusion-dei" class="drpdwn-toggle nav-link--who-we-are-diversity-equity-inclusion-dei" data-drupal-link-system-path="node/1158">Diversity, Equity & Inclusion (DE&I)</a> <ul class="dropdown-menu show lvl-2"> <li class="drpdwn-item"> <a href="/who-we-are/diversity-equity-inclusion-dei/employee-resource-groups-ergs" class="nav-link--who-we-are-diversity-equity-inclusion-dei-employee-resource-groups-ergs" data-drupal-link-system-path="node/1157">Employee Resource Groups (ERGs)</a> </li> </ul> </li> <li class="drpdwn-item"> <a href="/who-we-are/awards" class="nav-link--who-we-are-awards" data-drupal-link-system-path="node/1141">Awards</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/office-locations" class="nav-link--office-locations" data-drupal-link-system-path="node/1206">Office Locations</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> </ul> </li> <li class="nav-item menu-item--collapsed"> <a href="/how-we-partner" class="nav-link nav-link--how-we-partner" data-drupal-link-system-path="node/1090">How We Partner</a> </li> <li class="nav-item menu-item--expanded dropdown"> <a href="/solutions" title="Solutions Overview" class="nav-link drpdwn-toggle nav-link--solutions" data-drupal-link-system-path="node/1228">Solutions</a> <a href="/solutions" title="Solutions Overview" class="overview nav-link" data-drupal-link-system-path="node/1228">Solutions Overview</a> <ul class="dropdown-menu lvl-1"> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <a href="/solutions/clinical-development" class="drpdwn-toggle nav-link--solutions-clinical-development" data-drupal-link-system-path="node/1187">Clinical Development</a> <ul class="dropdown-menu show lvl-2"> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <span class="drpdwn-toggle nav-link-">PHASES</span> <ul class="dropdown-menu lvl-3"> <li class="drpdwn-item"> <a href="/solutions/clinical-development/early-phase" class="nav-link--solutions-clinical-development-early-phase" data-drupal-link-system-path="node/1184">Early Phase</a> </li> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <a href="/phase-ii-iv" class="drpdwn-toggle nav-link--phase-ii-iv" data-drupal-link-system-path="node/1336">Phase II-IV</a> <ul class="dropdown-menu lvl-4"> <li class="drpdwn-item"> <a href="/solutions/clinical-development/phase-ii-iv/biostatistics-and-statistical-programming" class="nav-link--solutions-clinical-development-phase-ii-iv-biostatistics-and-statistical-programming" data-drupal-link-system-path="node/88">Biostatistics and Statistical Programming</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/phase-ii-iv/clinical-data-management" class="nav-link--solutions-clinical-development-phase-ii-iv-clinical-data-management" data-drupal-link-system-path="node/1091">Clinical Data Management</a> </li> <li class="drpdwn-item"> <a href="/phase-ii-iv/clinical-monitoring" class="nav-link--phase-ii-iv-clinical-monitoring" data-drupal-link-system-path="node/1048">Clinical Monitoring</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/phase-ii-iv/drug-safety-and-pharmacovigilance" class="nav-link--solutions-clinical-development-phase-ii-iv-drug-safety-and-pharmacovigilance" data-drupal-link-system-path="node/1190">Drug Safety and Pharmacovigilance</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/phase-ii-iv/medical-writing" class="nav-link--solutions-clinical-development-phase-ii-iv-medical-writing" data-drupal-link-system-path="node/1106">Medical Writing</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/phase-ii-iv/trial-master-file-operations" class="nav-link--solutions-clinical-development-phase-ii-iv-trial-master-file-operations" data-drupal-link-system-path="node/1077">Trial Master File Operations</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/phase-ii-iv/investigator-management-solutions" class="nav-link--solutions-clinical-development-phase-ii-iv-investigator-management-solutions" data-drupal-link-system-path="node/1076">Investigator Management Solutions</a> </li> </ul> </li> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <a href="/real-world-evidence" class="drpdwn-toggle nav-link--real-world-evidence" data-drupal-link-system-path="node/2128">Real World Evidence</a> <ul class="dropdown-menu lvl-4"> <li class="drpdwn-item"> <a href="/solutions/consulting/health-economics-and-outcomes-research-heor" class="nav-link--solutions-consulting-health-economics-and-outcomes-research-heor" data-drupal-link-system-path="node/1095">HEOR</a> </li> </ul> </li> </ul> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/fsp-360" class="nav-link--solutions-clinical-development-fsp-360" data-drupal-link-system-path="node/1537">Functional Service Provider (FSP 360)</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/patient-powered-medicine" class="nav-link--solutions-clinical-development-patient-powered-medicine" data-drupal-link-system-path="node/1926">Patient-Powered Medicine</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/bioanalytical-solutions" class="nav-link--solutions-clinical-development-bioanalytical-solutions" data-drupal-link-system-path="node/1084">Bioanalytical Solutions</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/decentralized-solutions" class="nav-link--solutions-clinical-development-decentralized-solutions" data-drupal-link-system-path="node/1527">Decentralized & Hybrid Clinical Trials</a> </li> <li class="drpdwn-item"> <a href="/solutions/clinical-development/site-and-patient-access" class="nav-link--solutions-clinical-development-site-and-patient-access" data-drupal-link-system-path="node/1105">Site and Patient Access</a> </li> <li class="drpdwn-item"> <a href="/how-we-partner/trusted-process" class="nav-link--how-we-partner-trusted-process" data-drupal-link-system-path="node/1182">Trusted Process</a> </li> </ul> </li> <li class="drpdwn-item"> <a href="/solutions/medical-affairs" class="nav-link--solutions-medical-affairs" data-drupal-link-system-path="node/1185">Medical Affairs</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <a href="/solutions/commercial-delivery" class="drpdwn-toggle nav-link--solutions-commercial-delivery" data-drupal-link-system-path="node/1032">Commercial Delivery</a> <ul class="dropdown-menu show lvl-2"> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/full-service-commercialization" class="nav-link--solutions-commercial-delivery-full-service-commercialization" data-drupal-link-system-path="node/2052">Full-Service Commercialization</a> </li> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <a href="/solutions/commercial-delivery/deployment-solutions" class="drpdwn-toggle nav-link--solutions-commercial-delivery-deployment-solutions" data-drupal-link-system-path="node/1881">Deployment Solutions</a> <ul class="dropdown-menu lvl-3"> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/deployment-solutions/engagement-center" class="nav-link--solutions-commercial-delivery-deployment-solutions-engagement-center" data-drupal-link-system-path="node/1877">Engagement Center</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/deployment-solutions/field-sales-teams" class="nav-link--solutions-commercial-delivery-deployment-solutions-field-sales-teams" data-drupal-link-system-path="node/1882">Field Sales Teams</a> </li> <li class="drpdwn-item"> <a href="/sales-operations" class="nav-link--sales-operations" data-drupal-link-system-path="node/1891">Sales Operations</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/deployment-solutions/medical-science-liaisons-nurses" class="nav-link--solutions-commercial-delivery-deployment-solutions-medical-science-liaisons-nurses" data-drupal-link-system-path="node/1892">Medical Science Liaisons, Nurses</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/deployment-solutions/recruiting-and-direct-hire-solutions" class="nav-link--solutions-commercial-delivery-deployment-solutions-recruiting-and-direct-hire-solutions" data-drupal-link-system-path="node/1893">Recruiting and Direct Hire Solutions</a> </li> </ul> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/global-risk-management-and-rems" class="nav-link--solutions-commercial-delivery-global-risk-management-and-rems" data-drupal-link-system-path="node/2051">Global Risk Management and REMS</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/learning-solutions" class="nav-link--solutions-commercial-delivery-learning-solutions" data-drupal-link-system-path="node/1894">Learning Solutions</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/patient-support-services" class="nav-link--solutions-commercial-delivery-patient-support-services" data-drupal-link-system-path="node/2127">Patient Support Services</a> </li> <li class="drpdwn-item menu-item--expanded dropdown"> <span class="drp-icon"></span> <a href="/solutions/commercial-delivery/syneos-health-communications" class="drpdwn-toggle nav-link--solutions-commercial-delivery-syneos-health-communications" data-drupal-link-system-path="node/1058">Syneos Health Communications</a> <ul class="dropdown-menu lvl-3"> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/syneos-health-communications/healthcare-advertising" class="nav-link--solutions-commercial-delivery-syneos-health-communications-healthcare-advertising" data-drupal-link-system-path="node/1060">Healthcare Advertising</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/syneos-health-communications/medical-communications" class="nav-link--solutions-commercial-delivery-syneos-health-communications-medical-communications" data-drupal-link-system-path="node/1061">Medical Communications</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/syneos-health-communications/patient-advocacy" class="nav-link--solutions-commercial-delivery-syneos-health-communications-patient-advocacy" data-drupal-link-system-path="node/1183">Patient Advocacy</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/syneos-health-communications/healthcare-naming-brand-identity" class="nav-link--solutions-commercial-delivery-syneos-health-communications-healthcare-naming-brand-identity" data-drupal-link-system-path="node/1063">Healthcare Naming & Brand Identity</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/syneos-health-communications/payer-marketing" class="nav-link--solutions-commercial-delivery-syneos-health-communications-payer-marketing" data-drupal-link-system-path="node/1069">Payer Marketing</a> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/syneos-health-communications/healthcare-public-relations" class="nav-link--solutions-commercial-delivery-syneos-health-communications-healthcare-public-relations" data-drupal-link-system-path="node/1070">Healthcare Public Relations</a> </li> <li class="drpdwn-item"> <a href="/how-we-partner/human-behavioral-insights" class="nav-link--how-we-partner-human-behavioral-insights" data-drupal-link-system-path="node/1073">Human Behavioral Insights</a> </li> </ul> </li> <li class="drpdwn-item"> <a href="/solutions/commercial-delivery/value-and-access" class="nav-link--solutions-commercial-delivery-value-and-access" data-drupal-link-system-path="node/1086">Value and Access</a> </li> </ul> </li> <li class="drpdwn-item"> <a href="/solutions/consulting" class="nav-link--solutions-consulting" data-drupal-link-system-path="node/1092">Consulting</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> </ul> </li> <li class="nav-item menu-item--expanded active dropdown"> <a href="/therapeutic-depth" title="Therapeutic Depth Overview" class="nav-link active drpdwn-toggle nav-link--therapeutic-depth" data-drupal-link-system-path="node/1186">Therapeutic Depth</a> <a href="/therapeutic-depth" title="Therapeutic Depth Overview" class="overview nav-link" data-drupal-link-system-path="node/1186">Therapeutic Depth Overview</a> <ul class="dropdown-menu lvl-1"> <li class="drpdwn-item"> <a href="/therapeutic-depth/biosimilars" class="nav-link--therapeutic-depth-biosimilars" data-drupal-link-system-path="node/80">Biosimilars</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item active"> <a href="/therapeutic-depth/cardiovascular" class="active nav-link--therapeutic-depth-cardiovascular is-active" data-drupal-link-system-path="node/1031">Cardiovascular</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/cell-and-gene-therapy" class="nav-link--therapeutic-depth-cell-and-gene-therapy" data-drupal-link-system-path="node/1931">Cell and Gene Therapy</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/neuroscience" class="nav-link--therapeutic-depth-neuroscience" data-drupal-link-system-path="node/1180">Neuroscience</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/dermatology" class="nav-link--therapeutic-depth-dermatology" data-drupal-link-system-path="node/1536">Dermatology</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/endocrine-and-metabolic-clinical-trials" class="nav-link--therapeutic-depth-endocrine-and-metabolic-clinical-trials" data-drupal-link-system-path="node/1041">Endocrine and Metabolic Clinical Trials</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/gastroenterology" class="nav-link--therapeutic-depth-gastroenterology" data-drupal-link-system-path="node/1080">Gastroenterology</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/immunology-inflammation" class="nav-link--therapeutic-depth-immunology-inflammation" data-drupal-link-system-path="node/1081">Immunology & Inflammation</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/infectious-diseases-vaccines" class="nav-link--therapeutic-depth-infectious-diseases-vaccines" data-drupal-link-system-path="node/1088">Infectious Diseases & Vaccines</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/oncology-and-hematology" class="nav-link--therapeutic-depth-oncology-and-hematology" data-drupal-link-system-path="node/1065">Oncology and Hematology</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/ophthalmology" class="nav-link--therapeutic-depth-ophthalmology" data-drupal-link-system-path="node/1889">Ophthalmology</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/medical-device-and-diagnostics" class="nav-link--therapeutic-depth-medical-device-and-diagnostics" data-drupal-link-system-path="node/1042">Medical Device and Diagnostics</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/pediatrics-consortium" class="nav-link--therapeutic-depth-pediatrics-consortium" data-drupal-link-system-path="node/1036">Pediatrics Consortium</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/rare-disease-consortium" class="nav-link--therapeutic-depth-rare-disease-consortium" data-drupal-link-system-path="node/1037">Rare Disease Consortium</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/respiratory" class="nav-link--therapeutic-depth-respiratory" data-drupal-link-system-path="node/1033">Respiratory</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/therapeutic-depth/womens-health" class="nav-link--therapeutic-depth-womens-health" data-drupal-link-system-path="node/1087">Women's Health</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> </ul> </li> <li class="nav-item menu-item--expanded dropdown"> <a href="/technology-data" title="Technology & Data" class="nav-link drpdwn-toggle nav-link--technology-data" data-drupal-link-system-path="node/1880">Technology & Data</a> <a href="/technology-data" title="Technology & Data" class="overview nav-link" data-drupal-link-system-path="node/1880">Technology & Data</a> <ul class="dropdown-menu lvl-1"> <li class="drpdwn-item"> <a href="https://studykik.com/" target="_blank" class="nav-link-https--studykikcom-">Patient Recruitment for Clinical Trials (StudyKik)</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/technology-data/healthcare-business-intelligence-platform-kinetic" class="nav-link--technology-data-healthcare-business-intelligence-platform-kinetic" data-drupal-link-system-path="node/2058">Healthcare Business Intelligence Platform (Kinetic™)</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="https://www.rxdatascience.com/" target="_blank" class="nav-link-https--wwwrxdatasciencecom-">Biopharma Analytics Platform (RxDataScience)</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/how-we-partner/answersuite" class="nav-link--how-we-partner-answersuite" data-drupal-link-system-path="node/1178">Biopharmaceutical Syndicated Data (AnswerSuite)</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/delivery-excellence-veeva-cdms-implementation" class="nav-link--delivery-excellence-veeva-cdms-implementation" data-drupal-link-system-path="node/1126">Veeva CDMS</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> <li class="drpdwn-item"> <a href="/technology-data/clinical-trial-oversight-data-visualization-life-sciences" class="nav-link--technology-data-clinical-trial-oversight-data-visualization-life-sciences" data-drupal-link-system-path="node/1860">Clinical Study Oversight (Synopsis)</a> <ul class="dropdown-menu show lvl-2 phmenu-solutions d-none"></ul> </li> </ul> </li> <li class="nav-item"> <a href="/insights-hub" class="nav-link nav-link--insights-hub" data-drupal-link-system-path="node/45">Insights Hub</a> </li> </ul> </div> <div id="menu-search-box" class="col"> <i class="bi bi-search"></i> </div> </div> </nav> <div class="form-inline navbar-form justify-content-end"> <section class="row region region-header-form"> <div data-drupal-messages-fallback class="hidden"></div> </section> </div> </div> </div> </nav> <div class="dropdowners"></div> </header> <div class="featured-top"> <aside class="featured-top__inner section container-fluid clearfix" role="complementary"> </aside> </div> <div class="offcanvas offcanvas-start" tabindex="-1" id="offcanvasExample" aria-labelledby="offcanvasExampleLabel"> <div class="offcanvas-header"> <h5 class="offcanvas-title" id="offcanvasExampleLabel">Offcanvas</h5> <button type="button" class="btn-close text-reset" data-bs-dismiss="offcanvas" aria-label="Close"></button> </div> <div class="offcanvas-body"> <div> Some text as placeholder. In real life you can have the elements you have chosen. Like, text, images, lists, etc. </div> <div class="dropdown mt-3"> <button class="btn btn-secondary dropdown-toggle" type="button" id="dropdownMenuButton" data-bs-toggle="dropdown"> Dropdown button </button> <ul class="dropdown-menu" aria-labelledby="dropdownMenuButton"> <li> <a class="dropdown-item" href="#">Action</a> </li> <li> <a class="dropdown-item" href="#">Another action</a> </li> <li> <a class="dropdown-item" href="#">Something else here</a> </li> </ul> </div> </div> </div> <div id="search-layer" class="border-bottom border-light"> <div class="container d-flex align-items-center justify-content-center"> <div class="close-btn"> <i class="bi bi-x fs-4"></i> </div> <div class="row flex-column"> <h5>What are you looking for?</h5> <form id="menu-search-form" class="p-0 m-0 d-flex align-items-center" method="GET" action="/search"> <input type="text" placeholder="Search..." name="query" id="menu-search-query" class="form-control" value="" required/> <button type="submit" id="menu-search-button" class="btn btn-primary ms-1">Search</button> </form> </div> </div> </div> <div id="main-wrapper" class="layout-main-wrapper clearfix position-relative"> <div id="main" class="container-fluid g-0"> <div class=" clearfix"> <main class="main-content col" id="content" role="main"> <section class="section"> <a id="main-content" tabindex="-1"></a> <div id="block-bootstrap-syneos-sass-content" class="block block-system block-system-main-block"> <div class="content"> <div data-history-node-id="1031" class="node node--type-page node--view-mode-full ds-1col clearfix" typeof="schema:WebPage"> <div class="container"> <nav role="navigation" aria-label="breadcrumb" style=""> <ol class="breadcrumb"> <li class="breadcrumb-item"> <a href="/therapeutic-depth">Therapeutic Depth</a> </li> </ol> </nav> </div> <div > <h1 class="wp-block-sh-page-title has-text-align-center" data-type="sh/page-title"><span class="has-inline-color has-orange-color">Cardiovascular Solutions</span></h1> <p class="has-text-align-center container">Despite tremendous progress in improving cardiovascular outcomes, cardiovascular disease remains the leading cause of death in the US and around the world. Cardiovascular disease and quality of care remain urgent public health issues demanding solutions coupled with agility, speed and data-driven insights to improve outcomes.</p> <h3 class="has-text-align-center has-orange-color has-text-color padding-top"><span class="has-inline-color has-orange-color">Improving outcomes with agility, speed and data-driven insights</span></h3> <p class="has-text-align-center container">As a global leader in cardiovascular drug development (cardiovascular CRO), we work with innovative companies at the forefront of cardiovascular therapies. This includes small to midsize biotech companies who turn to our specialized Cardiovascular team for specialized cardiology therapeutic expertise, our therapeutic depth and our flexible, creative approach to meeting your most complex challenges.</p> <p class="has-text-align-center container padding-bottom">We’ve worked across the entire spectrum of cardiovascular indications including hypertension, atrial fibrillation, heart failure, ischemic heart disease, thrombosis, dyslipidemia, diabetes, obesity and many more. We are also experienced in the clinical development of new therapies such as stem cells, HFpEF, HFrEF,<br>SGLT-2 inhibitors, and we have run many large, global cardiovascular outcome trials (CVOT).</p> <div class="wp-block-sh-call-to-action container margin-top margin-bottom rounded" data-type="sh/call-to-action"><section><div class="row g-0 align-items-center" style="background:linear-gradient(90deg, #EB2A00 0%, #F14307 14%, #FF691E 54%, #FF8E1D 86%, #FE9E1A 100%)"> <div class="wp-block-column col-12 col-md"> <h3 class="has-white-color has-text-color">Ready to see what our cardiology team can do for you?</h3> </div> <div class="wp-block-column col-12 col-md-4"> <div class="wp-block-button alignright is-style-secondary btn-arrow form-anchor"><a class="wp-block-button__link">Contact Us</a></div> </div> </div></section></div> <div style="height:53px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-sh-card-image-panel btn-off container shadow" data-type="sh/card-image-panel"><div><section><div class="row g-0"> <div class="wp-block-column col-12 col-xl"> <figure class="wp-block-image size-card_image_panel_660x660_"><img src="/s3/files/styles/card_image_panel_660x660_/public/2023-05/mufid-majnun-3hTQWOv0yjQ-unsplash.jpg?itok=Gpbjt3kE" alt="" class="wp-image-416" data-entity-type="file" data-entity-uuid="d47a1a78-1e7c-4859-a3ff-d1e08475a343" data-image-style="original" /></figure></div> <div class="wp-block-column col-12 col-xl align-items-center d-flex"> <div class="wp-block-group col-card"> <h2>Minimizing patient burden, maximizing patient benefit in cardiovascular clinical research</h2> <p>The contributions patients can make to the cardiovascular clinical research enterprise are invaluable. We listen and learn from them to map their journey to inform study goals and reduce the burden of trial participation, using home health, telemedicine and digital technology platforms to facilitate decentralized solutions. </p> <div class="wp-block-button is-style-primary template-bt"><a class="wp-block-button__link" href="#">Discover Syneos One</a></div> </div> </div> </div></section></div></div> <div style="height:58px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-sh-two-column-highlight btn-off container margin-top rounded shadow" data-type="sh/two-column-highlight"><section><style>[bid="c6b570c3-008c-4592-bdef-fbf8bad2273f"] .wp-block-column:first-child {background-image: url(/sites/default/files/inline-images/BG_Abstract_Light-Orange%402x.jpg)</style><div class="tch-root row g-0 flex-row-reverse " bid="c6b570c3-008c-4592-bdef-fbf8bad2273f"> <div class="wp-block-column col-12 col-xl-6"> <div class="wp-block-group col-bg align-items-center d-flex"> <div class="wp-block-group"> <h3><span class="has-inline-color has-light-gray-3-color">Targeted and proven cardiovascular site network for high performance</span></h3> <p></p> <div class="wp-block-button template-bt btn-arrow"><a class="wp-block-button__link">cta button</a></div> </div> </div> </div> <div class="wp-block-column col-12 col-xl-6"> <p class="padding">With our dedicated focus on cardiovascular disease, we’ve built a global, trusted, network of more than 2,200 sites specializing in cardiovascular studies. These are the high-performing sites you want to work with in order to meet recruitment targets, enroll the right patients, optimize study start-up and ensure operational excellence with your cardiovascular trial.</p> <div class="wp-block-buttons padding"> <div class="wp-block-button is-style-primary"><a class="wp-block-button__link has-luminous-vivid-orange-to-vivid-red-gradient-background has-background" href="https://go.syneoshealth.com/l/63102/2024-11-26/4t6y6l/63102/1732652556ZFY8QEyv/Cardiovascular_Capabilities.pdf">View our capabilities</a></div> </div> <p></p> </div> </div></section></div> <div style="height:56px" aria-hidden="true" class="wp-block-spacer"></div> <div style="height:30px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-columns container"> <div class="wp-block-column"> <div class="wp-block-sh-two-column-highlight btn-on container padding-horizontal rounded shadow" data-type="sh/two-column-highlight"><section><style>[bid="a50e7cef-e7b4-4afc-b60f-484336af7ea0"] .wp-block-column:first-child {background-color: #FFFFFF</style><div class="tch-root row g-0" bid="a50e7cef-e7b4-4afc-b60f-484336af7ea0"> <div class="wp-block-group"> <div class="wp-block-column col-12"> <div class="wp-block-group col-bg align-items-center d-flex"> <div class="wp-block-group"> <h3 class="hascoloredborderleft" style="border-left:9px solid #EB3300;padding:10px 0 10px 20px"><meta charset="utf-8" /><span class="has-inline-color has-orange-color">Taking studies to where the patients are</span></h3> <p><meta charset="utf-8" /><span class="has-inline-color has-dark-gray-color">Digital health technologies have the potential to increase efficiency and data capture, while creating exciting new ways to accelerate patient access, improve retention and increase diversity. We combine deep insights, agile technologies, innovative trial design experience and operational excellence to bring clinical trials closer to the patient. </span></p> <div class="wp-block-button template-bt is-style-primary btn-arrow"><a class="wp-block-button__link" href="/how-we-partner/human-behavioral-insights">Learn more</a></div> </div> </div> </div> </div> </div></section></div> </div> </div> <div style="height:100px" aria-hidden="true" class="wp-block-spacer"></div> <h2 class="has-text-align-center has-orange-color has-text-color container">Contact Us</h2> <div class="wp-block-columns container"> <div class="wp-block-column"> <p><iframe src="https://go.syneoshealth.com/l/63102/2024-10-25/4t52x6" style="border: 0" width="100%" height="800" frameborder="0"></iframe></p> </div> </div> </div> </div> </div> </div> </section> </main> </div> </div> </div> <div class="container-fluid" id="get-in-touch"> <div class="container"> <div class="row flex-column flex-md-row align-items-center"> <div class="col logo text-center text-md-start mb-5 mb-md-0"> <a href="/"><img alt="Syneos Health logo" title="Syneos Health logo" src="https://ecdn.syneoshealth.com/s3fs-public/2023-05/syneos_logo_white.png?VersionId=vYInAS1QgzWmNpVV8ozGkm1jZOMXtOH0" typeof="foaf:Image" /> </a> </div> <div class="col social d-flex flex-row justify-content-center justify-content-md-start mb-5 mb-md-0"> <div class="me-3"> <a href="https://www.linkedin.com/company/11408925/" target="_blank" rel="noreferrer"><img alt="LinkedIn icon" title="LinkedIn icon" src="https://ecdn.syneoshealth.com/s3fs-public/2023-05/linkedin.png?VersionId=10ddZu8mqduauIXgBtX71xfWHkYM0J2f" typeof="foaf:Image" /> </a> </div> <div class="me-3"> <a href="https://twitter.com/syneoshealth" target="_blank" rel="noreferrer"><img alt="Twitter icon" title="Twitter icon" src="https://ecdn.syneoshealth.com/s3fs-public/2023-05/twitter.png?VersionId=mhx3LKvPRdMZVB.25_QRXgdjYRceazlX" typeof="foaf:Image" /> </a> </div> <div> <a href="https://www.facebook.com/SyneosHealth/" target="_blank" rel="noreferrer"><img alt="Facebook icon" title="Facebook icon" src="https://ecdn.syneoshealth.com/s3fs-public/2023-05/facebook.png?VersionId=IL1Q6eO.l_EmS_wDUxlqllQC1qMkoQgM" typeof="foaf:Image" /> </a> </div> </div> <div class="col col-md-auto flex-column flex-md-row text-end d-flex flex-row align-items-center"> <div class="me-md-3 mb-3 mb-md-0"> <span class="copy">Interested in Syneos Health?</span> </div> <div> <a href="/contact-us" class="btn btn-secondary">Get In Touch</a> </div> </div> </div> </div> </div> <footer class="site-footer"> <div class="container"> <div class="site-footer__top clearfix row"> <section class="col-md-4 region region-footer-first"> <div id="block-footertext-2" class="block block-block-content block-block-content15c76c29-fe56-4295-b46d-48697f581986"> <div class="content"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>Syneos Health<sup>® </sup>is a leading fully integrated biopharmaceutical solutions organization built to accelerate customer success. We translate unique clinical, medical affairs and commercial insights into outcomes to address modern market realities. Together we share insights, use the latest technologies and apply advanced business practices to speed our customers’ delivery of important therapies to patients. We support a diverse, equitable and inclusive culture.</p> </div> </div> </div> </section> <section class="col-md-4 region region-footer-second"> <nav role="navigation" aria-labelledby="block-corporatelinks-menu" id="block-corporatelinks" class="block block-menu navigation menu--corporate-links"> <h2 id="block-corporatelinks-menu">Corporate Links</h2> <ul class="clearfix nav"> <li class="nav-item"> <a href="/who-we-are" class="nav-link nav-link--who-we-are" data-drupal-link-system-path="node/1170">Who We Are</a> </li> <li class="nav-item"> <a href="/our-agencies" class="nav-link nav-link--our-agencies" data-drupal-link-system-path="node/1486">Our Agencies</a> </li> <li class="nav-item"> <a href="/careers" class="nav-link nav-link--careers" data-drupal-link-system-path="node/1174">Careers</a> </li> <li class="nav-item"> <a href="https://go.syneoshealth.com/l/63102/2024-06-06/4svyf3/63102/1717693417Hw85tKr0/Supplier_Code_2024.pdf" target="_blank" class="nav-link nav-link-https--gosyneoshealthcom-l-63102-2024-06-06-4svyf3-63102-1717693417hw85tkr0-supplier-code-2024pdf">Supplier code of conduct</a> </li> <li class="nav-item"> <a href="https://synopsisconnect.syneoshealth.com/" target="_blank" class="nav-link nav-link-https--synopsisconnectsyneoshealthcom-">Synopsis Connect</a> </li> <li class="nav-item"> <a href="/supplier-diversity" class="nav-link nav-link--supplier-diversity" data-drupal-link-system-path="node/1192">Supplier diversity and inclusion</a> </li> <li class="nav-item"> <a href="/news-releases" class="nav-link nav-link--news-releases" data-drupal-link-system-path="node/92">News</a> </li> <li class="nav-item"> <a href="https://go.syneoshealth.com/l/63102/2023-05-19/4r7r1c/63102/1684504635rIQDnHGa/Supplier_Terms_and_Conditions_January_2018.pdf" target="_blank" class="nav-link nav-link-https--gosyneoshealthcom-l-63102-2023-05-19-4r7r1c-63102-1684504635riqdnhga-supplier-terms-and-conditions-january-2018pdf">Supplier terms and conditions</a> </li> <li class="nav-item"> <a href="/events" class="nav-link nav-link--events" data-drupal-link-system-path="node/1235">Events</a> </li> <li class="nav-item"> <a href="/office-locations" class="nav-link nav-link--office-locations" data-drupal-link-system-path="node/1206">Office Locations</a> </li> </ul> </nav> </section> <section class="col-md-2 region region-footer-third"> <nav role="navigation" aria-labelledby="block-oursolutions-menu" id="block-oursolutions" class="block block-menu navigation menu--our-solutions"> <h2 id="block-oursolutions-menu">Our Solutions</h2> <ul class="clearfix nav"> <li class="nav-item"> <a href="/how-we-partner" class="nav-link nav-link--how-we-partner" data-drupal-link-system-path="node/1090">How We Partner</a> </li> <li class="nav-item"> <a href="/insights-hub" class="nav-link nav-link--insights-hub" data-drupal-link-system-path="node/45">Insights Hub</a> </li> <li class="nav-item"> <a href="/therapeutic-depth" class="nav-link nav-link--therapeutic-depth" data-drupal-link-system-path="node/1186">Therapeutic Depth</a> </li> </ul> </nav> </section> <section class="col-md-2 region region-footer-fourth"> <nav role="navigation" aria-labelledby="block-ourresources-menu" id="block-ourresources" class="block block-menu navigation menu--our-resources"> <h2 id="block-ourresources-menu">Our Resources</h2> <ul class="clearfix nav"> <li class="nav-item"> <a href="https://secure.ethicspoint.com/domain/media/en/gui/42406/index.html" class="nav-link nav-link-https--secureethicspointcom-domain-media-en-gui-42406-indexhtml">Business Ethics Helpline</a> </li> <li class="nav-item"> <a href="https://www.syneoshealth.com/legal" class="nav-link nav-link-https--wwwsyneoshealthcom-legal">Legal Notices</a> </li> <li class="nav-item"> <a href="https://www.participants.syneoshealth.com/en/" class="nav-link nav-link-https--wwwparticipantssyneoshealthcom-en-">Study Participants</a> </li> <li class="nav-item"> <a href="https://www.syneoshealth.com/sitemap.xml" class="nav-link nav-link-https--wwwsyneoshealthcom-sitemapxml">Sitemap</a> </li> </ul> </nav> </section> </div> </div> <div class="container-fluid g-0"> <div class="site-footer__bottom"> <section class="region region-footer-fifth"> <div id="block-footernavigation" class="block block-system block-system-menu-blockfooter-navigation d-flex align-items-center justify-content-center"> <span>© 2024 Syneos Health. All Rights Reserved</span> <div class="content"> <ul class="clearfix nav"> <li class="nav-item"> <a href="/syneos-health-website-terms-use" class="nav-link nav-link--syneos-health-website-terms-use" data-drupal-link-system-path="node/1198">Terms of Use</a> </li> <li class="nav-item"> <a href="/syneos-health-tm-privacy-statement-and-terms-use" class="nav-link nav-link--syneos-health-tm-privacy-statement-and-terms-use" data-drupal-link-system-path="node/1204">Privacy Notice</a> </li> <li class="nav-item"> <a href="/ccpa-privacy-notice-california-residents#tracking-opt-out" class="nav-link nav-link--ccpa-privacy-notice-california-residentstracking-opt-out" data-drupal-link-system-path="node/1196">Online Tracking Opt-Out</a> </li> </ul> </div> </div> </section> </div> </div> </footer> </div> </div> </div> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","scriptPath":null,"pathPrefix":"","currentPath":"node\/1031","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"field_group":{"html_element":{"mode":"default","context":"view","settings":{"classes":"container","show_empty_fields":false,"id":"","element":"div","show_label":false,"label_element":"h3","label_element_classes":"","attributes":"","effect":"none","speed":"fast"}}},"user":{"uid":0,"permissionsHash":"ae74d1b4fc27262fce4ec1869fcb1f86612163c8d0ecdd38faa5210e2b94160b"}}</script> <script src="/core/assets/vendor/jquery/jquery.min.js?v=3.6.3"></script> <script src="/core/misc/polyfills/element.matches.js?v=9.5.10"></script> <script src="/core/misc/polyfills/object.assign.js?v=9.5.10"></script> <script src="/core/misc/polyfills/array.find.js?v=9.5.10"></script> <script src="/core/assets/vendor/es6-promise/es6-promise.auto.min.js?v=4.2.8"></script> <script src="/core/assets/vendor/once/once.min.js?v=1.0.1"></script> <script src="/core/assets/vendor/jquery-once/jquery.once.min.js?v=2.2.3"></script> <script src="/core/misc/drupalSettingsLoader.js?v=9.5.10"></script> <script src="/core/misc/drupal.js?v=9.5.10"></script> <script src="/core/misc/drupal.init.js?v=9.5.10"></script> <script src="https://static.addtoany.com/menu/page.js" async></script> <script src="/modules/contrib/addtoany/js/addtoany.js?v=9.5.10"></script> <script src="/core/misc/jquery.once.bc.js?v=9.5.10"></script> <script src="/core/assets/vendor/popperjs/popper.min.js?v=2.11.6"></script> <script src="/themes/contrib/bootstrap_barrio/js/affix.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/bootstrap.min.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/barrio.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/custom.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/navigation.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/mobile-nav.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/mobile-secondary-nav.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/bootstrap5-dropdown-ml-hack.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/components/mobile-nav.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/components/secondary-nav.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/components/exposed-filters.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/components/search.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/components/navigation.js?v=9.5.10"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/pardot.js?v=9.5.10"></script> <script src="https://sdk.ceros.com/embedded-player-sdk-v5.min.js" type="text/javascript" async></script> <script src="https://labs.ceros.com/sdk-plugins/deep-linking/deep-linking-plugin-v2.min.js" id="ceros-deep-linking-plugin" type="text/javascript" async data-is-embedded="yes"></script> <script src="https://cdn.cookielaw.org/scripttemplates/otSDKStub.js" type="text/javascript" charset="UTF-8" data-domain-script="585b12ad-1feb-44cf-a873-87f9415ed759"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/vendor/pardot-web-tracking-prod.js?snlljb" type="text/plain" class="optanon-category-C0004"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/vendor/onetrust.js?v=1.0.0" type="text/javascript"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/vendor/demandbase.js?v=1.0.0" type="text/plain" class="optanon-category-C0004"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/vendor/accessibe.js?v=1.0.0" type="text/plain" class="optanon-category-C0004"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/vendor/gclid.min.js?v=1.0.0" type="text/plain" class="optanon-category-C0004"></script> <script src="/themes/custom/bootstrap_syneos_sass/js/event-cta.js?snlljb"></script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.nr-data.net","licenseKey":"NRJS-aaae99226ce3b76ac6a","applicationID":"1573558859","transactionName":"NlMAZkZWC0tYURVaWw8ZI1FAXgpWFkIAVFE+VQNRXFI=","queueTime":0,"applicationTime":33,"atts":"GhQDEA5MGEU=","errorBeacon":"bam.nr-data.net","agent":""}</script></body> </html>