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Walleye epidermal hyperplasia virus - Wikipedia

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<div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="cdx-message cdx-message--block cdx-message--warning"><span class="cdx-message__icon"></span><div class="cdx-message__content">The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.</div></div><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><p class="mw-empty-elt"> </p> <table class="infobox biota biota-infobox"> <tbody><tr> <th colspan="2" class="section-header" style="background:rgb(250,250,190);">Walleye epidermal hyperplasia virus </th></tr> <tr> <th colspan="2" class="section-header" style="min-width:15em;text-align:center;background:rgb(250,250,190);"><a href="/wiki/Taxonomy_(biology)" title="Taxonomy (biology)">Scientific classification</a><span class="plainlinks" style="font-size:smaller; float:right; padding-right:0.4em; margin-left:-3em;"><span typeof="mw:File"><a href="/wiki/Template:Taxonomy/Epsilonretrovirus" title="Edit this classification"><img alt="Edit this classification" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/15px-OOjs_UI_icon_edit-ltr.svg.png" decoding="async" width="15" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/23px-OOjs_UI_icon_edit-ltr.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8a/OOjs_UI_icon_edit-ltr.svg/30px-OOjs_UI_icon_edit-ltr.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span> </th></tr> <tr> <td>(unranked): </td> <td><a href="/wiki/Virus" title="Virus">Virus</a> </td></tr> <tr> <td><i>Realm</i>: </td> <td><a href="/wiki/Riboviria" title="Riboviria"><i>Riboviria</i></a> </td></tr> <tr> <td>Kingdom: </td> <td><a href="/wiki/Revtraviricetes" title="Revtraviricetes"><i>Pararnavirae</i></a> </td></tr> <tr> <td>Phylum: </td> <td><a href="/wiki/Revtraviricetes" title="Revtraviricetes"><i>Artverviricota</i></a> </td></tr> <tr> <td>Class: </td> <td><a href="/wiki/Revtraviricetes" title="Revtraviricetes"><i>Revtraviricetes</i></a> </td></tr> <tr> <td>Order: </td> <td><a href="/wiki/Ortervirales" title="Ortervirales"><i>Ortervirales</i></a> </td></tr> <tr> <td>Family: </td> <td><a href="/wiki/Retrovirus" title="Retrovirus"><i>Retroviridae</i></a> </td></tr> <tr> <td>Subfamily: </td> <td><a href="/wiki/Orthoretrovirinae" title="Orthoretrovirinae"><i>Orthoretrovirinae</i></a> </td></tr> <tr> <td>Genus: </td> <td><a href="/wiki/Epsilonretrovirus" title="Epsilonretrovirus"><i>Epsilonretrovirus</i></a> </td></tr> <tr> <th colspan="2" class="section-header" style="background:rgb(250,250,190);">Groups included </th></tr> <tr> <td colspan="2" class="section-content"> <ul><li><i><a href="/wiki/Walleye_epidermal_hyperplasia_virus_1" class="mw-redirect" title="Walleye epidermal hyperplasia virus 1">Walleye epidermal hyperplasia virus 1</a></i></li> <li><i><a href="/wiki/Walleye_epidermal_hyperplasia_virus_2" class="mw-redirect" title="Walleye epidermal hyperplasia virus 2">Walleye epidermal hyperplasia virus 2</a></i></li></ul> </td></tr> <tr> <th colspan="2" class="section-header" style="background:rgb(250,250,190);"><a href="/wiki/Cladistics" title="Cladistics">Cladistically</a> included but traditionally excluded taxa </th></tr> <tr> <td colspan="2" class="section-content"> <p><i><a href="/wiki/Walleye_dermal_sarcoma_virus" title="Walleye dermal sarcoma virus">Walleye dermal sarcoma virus</a></i> </p> </td></tr></tbody></table><style data-mw-deduplicate="TemplateStyles:r1227369696">.mw-parser-output table.biota-infobox{text-align:left;width:200px;font-size:100%}body.skin--responsive .mw-parser-output table.biota-infobox td:not(.image-section){padding:2px 10px}.mw-parser-output table.biota-infobox th.section-header{text-align:center}.mw-parser-output table.biota-infobox td.section-content{text-align:left;padding:0 0.25em}.mw-parser-output table.biota-infobox td.list-section{text-align:left;padding:0 0.25em}.mw-parser-output table.biota-infobox td.taxon-section{text-align:left;padding:0 0.25em}.mw-parser-output table.biota-infobox td.image-section{text-align:center;font-size:88%}.mw-parser-output table.biota-infobox table.taxonomy{margin:0 auto;text-align:left;background:transparent;padding:2px}.mw-parser-output table.biota-infobox table.taxonomy tr{vertical-align:top}.mw-parser-output table.biota-infobox table.taxonomy td{padding:1px}</style> <p>The <b>walleye epidermal hyperplasia viruses</b> are two species of <a href="/wiki/Retrovirus" title="Retrovirus">retroviruses</a> classified under <i><a href="/wiki/Epsilonretrovirus" title="Epsilonretrovirus">Epsilonretrovirus</a></i>, a genus in the family of <i><a href="/wiki/Retroviridae" class="mw-redirect" title="Retroviridae">Retroviridae</a></i>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> There are three genome sequenced and identified <a href="/wiki/Exogenous" class="mw-redirect" title="Exogenous">exogenous</a> retroviruses of this genus which include two known types (<b>WEHV-1</b> and <b>WEHV-2</b>) associated with walleye epidermal hyperplasia disease. Both viral types are confirmed to be the causative agents of the <a href="/wiki/Neoplastic" class="mw-redirect" title="Neoplastic">neoplastic</a> condition in the freshwater fish species, the North American <a href="/wiki/Walleye" title="Walleye">walleye</a> <i>(Sander vitreus)</i>. The specific association of retroviral infection with proliferative lesions in fish is based on the presence of retrovirus-like particles (observed via electron microscopy) and <a href="/wiki/Reverse_transcriptase" title="Reverse transcriptase">reverse transcriptase</a> activity (using reverse transcriptase <a href="/wiki/Polymerase_chain_reaction" title="Polymerase chain reaction">polymerase chain reaction</a> techniques) from neoplastic tissue. Although both virus types have been observed in lesions of diseased fish, each cell of the infected tissue is host to a specific virus. Transmission studies have also shown that WEHV-2 has been the more proliferative agent of the condition as compared to WEHV-1.<sup id="cite_ref-WDSV_2-0" class="reference"><a href="#cite_note-WDSV-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pmid10516048_3-0" class="reference"><a href="#cite_note-pmid10516048-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Phylogeny">Phylogeny</h2></div> <p>Phylogenetic analysis of the three confirmed <a href="/wiki/Epsilonretrovirus" title="Epsilonretrovirus">Epsilonretroviruses</a> shows they are related. After cloning techniques, sequence analysis determined that WEHV-1 and WEHV-2 are similar in size and share 95% <a href="/wiki/Amino_acid" title="Amino acid">amino acid</a> identity in the <i>pol</i> region of <a href="/wiki/Reverse_transcriptase" title="Reverse transcriptase">reverse transcriptase</a>. This finding suggests that they are different strains of the same virus or likely distinct species. The two types of WEHV also share over 80% of their amino acid sequence with the third member of the epsilonretrovirus genus. Included in this analysis was the observation of a homologous genomic organization in all three Epsilonretroviruses.<sup id="cite_ref-WEHV_4-0" class="reference"><a href="#cite_note-WEHV-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Condition">Condition</h2></div> <p>Walleye epidermal hyperplasia lesions are characteristically broad, flat, translucent plaques that range in size (2–50&#160;mm in diameter). Lesions are most often observed in sexually mature fish although transmission studies have shown that fingerling fish can be infected using cell-free virus components extracted from lesions. Multiple growths are also known to coalesce into larger lesions. Seasonal observations of the fish by scientists and sportsmen show a high incidence of the condition during the late fall, winter, and early spring months. Mortality in the host fish is hypothesized to be less related to the virus and more to secondary infections that invade necrotic tissue. These viruses have evolved a means to maintain a fine balance between its own proliferation and leaving behind a fit and reproductive host.<sup id="cite_ref-WDSV_2-1" class="reference"><a href="#cite_note-WDSV-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Transmission_and_epidemiology">Transmission and epidemiology</h2></div> <p>As with other skin lesion retroviruses, the in-lake transmission of the WEHV particles appears to be the result of contact with water harboring released infectious viral particles or close contact with other fish. The infection proliferates in temperatures between 0–5&#160;°C (32–41&#160;°F), and this may be why it occurs primarily in the fall and spring. With this seasonal prevalence, it is suggested that an inverse relationship exists between water temperature and skin lesion size/abundance. This is especially evident in the fact that few walleye show signs of the condition during the summer months. The nature of the seasonality of this condition is linked to a couple possible hypotheses: (1) low water temperatures and immune suppression, and (2) the physiological stress associated with spring spawning. It is important to note that this disease is not classified as <a href="/wiki/Zoonotic" class="mw-redirect" title="Zoonotic">zoonotic</a> and is not known to infect humans.<sup id="cite_ref-Oneida_5-0" class="reference"><a href="#cite_note-Oneida-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Molecular_biology_and_oncogenesis_studies">Molecular biology and oncogenesis studies</h2></div> <p>Molecular studies of retroviruses have been partly responsible for elucidating the mechanisms responsible for <a href="/wiki/Oncogenesis" class="mw-redirect" title="Oncogenesis">oncogenesis</a>. The Epsilonretroviruses provide a unique model for understanding the development and regression of tumors due to its seasonal prevalence and genetic evolutionary baggage. Proteins encoded by these viruses function in cell cycle regulation, alteration of cell-signaling pathways to promote proliferation and suppression of host cell apoptosis, and induction of apoptosis. The genetic and transcriptional similarities of the three classified <i>Epsilonrertovirus</i> suggest that these viruses share homologous mechanisms to replicate and proliferate.<sup id="cite_ref-WDSV_2-2" class="reference"><a href="#cite_note-WDSV-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pmid10516048_3-1" class="reference"><a href="#cite_note-pmid10516048-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://viralzone.expasy.org/all_by_species/92.html">Epsilonretrovirus</a>, Viral Zone</span> </li> <li id="cite_note-WDSV-2"><span class="mw-cite-backlink">^ <a 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virus">Duck hepatitis B virus</a></li> <li><a href="/wiki/Heron_hepatitis_B_virus" class="mw-redirect" title="Heron hepatitis B virus">Heron hepatitis B virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Herpetohepadnavirus&amp;action=edit&amp;redlink=1" class="new" title="Herpetohepadnavirus (page does not exist)">Herpetohepadnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Metahepadnavirus&amp;action=edit&amp;redlink=1" class="new" title="Metahepadnavirus (page does not exist)">Metahepadnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Orthohepadnavirus" title="Orthohepadnavirus">Orthohepadnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ground_squirrel_hepatitis_virus" title="Ground squirrel hepatitis virus">Ground squirrel hepatitis virus</a></li> <li><a href="/wiki/Hepatitis_B_virus" title="Hepatitis B virus">Hepatitis B virus</a></li> <li><a href="/wiki/Woodchuck_hepatitis_virus" title="Woodchuck hepatitis virus">Woodchuck hepatitis virus</a></li> <li><a href="/wiki/Woolly_monkey_hepatitis_B_virus" title="Woolly monkey hepatitis B virus">Woolly monkey hepatitis B virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Parahepadnavirus&amp;action=edit&amp;redlink=1" class="new" title="Parahepadnavirus (page does not exist)">Parahepadnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Ortervirales" title="Ortervirales">Ortervirales</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">(<a href="/wiki/SsRNA-RT_virus" class="mw-redirect" title="SsRNA-RT virus">ssRNA-RT viruses</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Belpaoviridae" class="mw-redirect" title="Belpaoviridae">Belpaoviridae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Semotivirus" scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Semotivirus" title="Semotivirus">Semotivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Caenorhabditis_elegans_Cer13_virus" title="Caenorhabditis elegans Cer13 virus">Caenorhabditis elegans Cer13 virus</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Metaviridae" title="Metaviridae">Metaviridae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Errantivirus&amp;action=edit&amp;redlink=1" class="new" title="Errantivirus (page does not exist)">Errantivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Metavirus" title="Metavirus">Metavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Caenorhabditis_elegans_Cer1_virus" title="Caenorhabditis elegans Cer1 virus">Caenorhabditis elegans Cer1 virus</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Pseudoviridae" title="Pseudoviridae">Pseudoviridae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Hemivirus&amp;action=edit&amp;redlink=1" class="new" title="Hemivirus (page does not exist)">Hemivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Pseudovirus_(genus)" class="mw-redirect" title="Pseudovirus (genus)">Pseudovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Sirevirus&amp;action=edit&amp;redlink=1" class="new" title="Sirevirus (page does not exist)">Sirevirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Retrovirus" title="Retrovirus">Retroviridae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Orthoretrovirinae" title="Orthoretrovirinae">Orthoretrovirinae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Alpharetrovirus" title="Alpharetrovirus">Alpharetrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Avian_sarcoma_leukosis_virus" title="Avian sarcoma leukosis virus">Avian sarcoma leukosis virus</a></li> <li><a href="/wiki/Rous_sarcoma_virus" title="Rous sarcoma virus">Rous sarcoma virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Betaretrovirus" title="Betaretrovirus">Betaretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Mouse_mammary_tumor_virus" title="Mouse mammary tumor virus">Mouse mammary tumor virus</a></li> <li><a href="/wiki/Jaagsiekte_sheep_retrovirus" title="Jaagsiekte sheep retrovirus">Jaagsiekte sheep retrovirus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Deltaretrovirus" title="Deltaretrovirus">Deltaretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Human_T-lymphotropic_virus" class="mw-redirect" title="Human T-lymphotropic virus">Human T-lymphotropic virus</a> (<a href="/wiki/Human_T-lymphotropic_virus_1" title="Human T-lymphotropic virus 1">HTLV-1</a></li> <li><a href="/wiki/Human_T-lymphotropic_virus_2" title="Human T-lymphotropic virus 2">HTLV-2</a>, 3, 4)</li> <li><a href="/wiki/Simian-T-lymphotropic_virus" class="mw-redirect" title="Simian-T-lymphotropic virus">Simian-T-lymphotropic virus</a> (types 1-4)</li> <li><a href="/wiki/Bovine_leukemia_virus" title="Bovine leukemia virus">Bovine leukemia virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Epsilonretrovirus" title="Epsilonretrovirus">Epsilonretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a class="mw-selflink selflink">Walleye epidermal hyperplasia virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Gammaretrovirus" title="Gammaretrovirus">Gammaretrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Murine_leukemia_virus" title="Murine leukemia virus">Murine leukemia virus</a></li> <li><a href="/wiki/Abelson_murine_leukemia_virus" title="Abelson murine leukemia virus">Abelson murine leukemia virus</a></li> <li><a href="/wiki/Friend_virus" title="Friend virus">Friend virus</a></li> <li><a href="/wiki/Feline_leukemia_virus" title="Feline leukemia virus">Feline leukemia virus</a></li> <li><a href="/wiki/Koala_retrovirus" title="Koala retrovirus">Koala retrovirus</a> (KoRV)</li> <li><a href="/wiki/Xenotropic_murine_leukemia_virus-related_virus" class="mw-redirect" title="Xenotropic murine leukemia virus-related virus">Xenotropic murine leukemia virus-related virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Lentivirus" title="Lentivirus">Lentivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/HIV" title="HIV">HIV</a> (human immunodeficiency viruses)</li> <li><a href="/wiki/Simian_immunodeficiency_virus" title="Simian immunodeficiency virus">Simian immunodeficiency viruses</a> (SIV)</li> <li><a href="/wiki/Feline_immunodeficiency_virus" title="Feline immunodeficiency virus">Feline immunodeficiency virus</a> (FIV)</li> <li><a href="/wiki/Puma_lentivirus" title="Puma lentivirus">Puma lentivirus</a> (PLV)</li> <li><a href="/wiki/Equine_infectious_anemia" title="Equine infectious anemia">Equine infectious anemia virus</a> (EIAV)</li> <li><a href="/wiki/Bovine_immunodeficiency_virus" title="Bovine immunodeficiency virus">Bovine immunodeficiency virus</a> (BIV)</li> <li><a href="/wiki/Caprine_arthritis_encephalitis_virus" title="Caprine arthritis encephalitis virus">Caprine arthritis encephalitis virus</a></li> <li><a href="/wiki/Visna-maedi_virus" title="Visna-maedi virus">Visna-maedi virus</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Spumaretrovirinae" title="Spumaretrovirinae">Spumaretrovirinae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Bovispumavirus&amp;action=edit&amp;redlink=1" class="new" title="Bovispumavirus (page does not exist)">Bovispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Equispumavirus&amp;action=edit&amp;redlink=1" class="new" title="Equispumavirus (page does not exist)">Equispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Felispumavirus&amp;action=edit&amp;redlink=1" class="new" title="Felispumavirus (page does not exist)">Felispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Feline_foamy_virus" title="Feline foamy virus">Feline foamy virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Prosimiispumavirus&amp;action=edit&amp;redlink=1" class="new" title="Prosimiispumavirus (page does not exist)">Prosimiispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Simiispumavirus&amp;action=edit&amp;redlink=1" class="new" title="Simiispumavirus (page does not exist)">Simiispumavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Simian_foamy_virus" class="mw-redirect" title="Simian foamy virus">Simian foamy virus</a></li> <li><a href="/wiki/Human_foamy_virus" title="Human foamy virus">Human foamy virus</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">(<a href="/wiki/DsDNA-RT_virus" class="mw-redirect" title="DsDNA-RT virus">dsDNA-RT viruses</a>)</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Caulimoviridae" scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Caulimoviridae" title="Caulimoviridae">Caulimoviridae</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Badnavirus" title="Badnavirus">Badnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Banana_streak_MY_virus" title="Banana streak MY virus">Banana streak MY virus</a></li> <li><a href="/wiki/Cacao_swollen_shoot_virus" title="Cacao swollen shoot virus">Cacao swollen shoot virus</a></li> <li><a href="/wiki/Kalanchoe_top-spotting_virus" title="Kalanchoe top-spotting virus">Kalanchoe top-spotting virus</a></li> <li><a href="/wiki/Rubus_yellow_net_virus" title="Rubus yellow net virus">Rubus yellow net virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Caulimovirus" title="Caulimovirus">Caulimovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Carnation_etched_ring_virus" title="Carnation etched ring virus">Carnation etched ring virus</a></li> <li><a href="/wiki/Cauliflower_mosaic_virus" title="Cauliflower mosaic virus">Cauliflower mosaic virus</a></li> <li><a href="/wiki/Strawberry_vein_banding_virus" title="Strawberry vein banding virus">Strawberry vein banding virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Cavemovirus" title="Cavemovirus">Cavemovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Cassava_vein_mosaic_virus" title="Cassava vein mosaic virus">Cassava vein mosaic virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Dioscovirus&amp;action=edit&amp;redlink=1" class="new" title="Dioscovirus (page does not exist)">Dioscovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Petuvirus" title="Petuvirus">Petuvirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Rosadnavirus&amp;action=edit&amp;redlink=1" class="new" title="Rosadnavirus (page does not exist)">Rosadnavirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Ruflodivirus&amp;action=edit&amp;redlink=1" class="new" title="Ruflodivirus (page does not exist)">Ruflodivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Solendovirus" title="Solendovirus">Solendovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Soymovirus" title="Soymovirus">Soymovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Soybean_chlorotic_mottle_virus" title="Soybean chlorotic mottle virus">Soybean chlorotic mottle virus</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/wiki/Tungrovirus" title="Tungrovirus">Tungrovirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i><a href="/w/index.php?title=Vaccinivirus&amp;action=edit&amp;redlink=1" class="new" title="Vaccinivirus (page does not exist)">Vaccinivirus</a></i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li class="mw-empty-elt"></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Endogenous_retrovirus" title="Endogenous retrovirus">Endogenous</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ERV-Fc" title="ERV-Fc">ERV-Fc</a></li> <li><a href="/wiki/Syncytin-1" title="Syncytin-1">ERVWE1</a></li> <li><a href="/wiki/HCP5" title="HCP5">HCP5</a></li> <li><a href="/wiki/Human_teratocarcinoma-derived_virus" class="mw-redirect" title="Human teratocarcinoma-derived virus">Human teratocarcinoma-derived virus</a></li> <li><a href="/wiki/Human_Endogenous_Retrovirus-W" class="mw-redirect" title="Human Endogenous Retrovirus-W">Human Endogenous Retrovirus-W</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Taxon_identifiers" style="padding:3px"><table class="nowraplinks hlist navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div id="Taxon_identifiers" style="font-size:114%;margin:0 4em"><a href="/wiki/Help:Taxon_identifiers" title="Help:Taxon identifiers">Taxon identifiers</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align: left;"><i>Walleye epidermal hyperplasia virus 1</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><span style="white-space:nowrap;"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a>: <span class="uid"><span class="external"><a href="https://www.wikidata.org/wiki/Q18976265" class="extiw" title="wikidata:Q18976265">Q18976265</a></span></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Wikispecies" title="Wikispecies">Wikispecies</a>: <span class="uid"><span class="external"><a href="https://species.wikimedia.org/wiki/Walleye_epidermal_hyperplasia_virus_1" class="extiw" title="wikispecies:Walleye epidermal hyperplasia virus 1">Walleye epidermal hyperplasia virus 1</a></span></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Catalogue_of_Life" title="Catalogue of Life">CoL</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.catalogueoflife.org/data/taxon/7G6DL">7G6DL</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Encyclopedia_of_Life" title="Encyclopedia of Life">EoL</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://eol.org/pages/540030">540030</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Interim_Register_of_Marine_and_Nonmarine_Genera" title="Interim Register of Marine and Nonmarine Genera">IRMNG</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.irmng.org/aphia.php?p=taxdetails&amp;id=11461188">11461188</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/National_Center_for_Biotechnology_Information" title="National Center for Biotechnology Information">NCBI</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=64462">64462</a></span></span></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;text-align: left;"><i>Walleye epidermal hyperplasia virus 2</i></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><span style="white-space:nowrap;"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a>: <span class="uid"><span class="external"><a href="https://www.wikidata.org/wiki/Q18976268" class="extiw" title="wikidata:Q18976268">Q18976268</a></span></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Wikispecies" title="Wikispecies">Wikispecies</a>: <span class="uid"><span class="external"><a href="https://species.wikimedia.org/wiki/Walleye_epidermal_hyperplasia_virus_2" class="extiw" title="wikispecies:Walleye epidermal hyperplasia virus 2">Walleye epidermal hyperplasia virus 2</a></span></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Catalogue_of_Life" title="Catalogue of Life">CoL</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.catalogueoflife.org/data/taxon/7G6DM">7G6DM</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Encyclopedia_of_Life" title="Encyclopedia of Life">EoL</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://eol.org/pages/540028">540028</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Interim_Register_of_Marine_and_Nonmarine_Genera" title="Interim Register of Marine and Nonmarine Genera">IRMNG</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.irmng.org/aphia.php?p=taxdetails&amp;id=11461189">11461189</a></span></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/National_Center_for_Biotechnology_Information" title="National Center for Biotechnology Information">NCBI</a>: <span class="uid"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&amp;id=64461">64461</a></span></span></li></ul> </div></td></tr></tbody></table></div> <!-- NewPP limit report Parsed by mw‐web.codfw.main‐f69cdc8f6‐cnfgh Cached time: 20241123181148 Cache expiry: 2592000 Reduced expiry: false Complications: [vary‐revision‐sha1, show‐toc] CPU time usage: 0.475 seconds Real time usage: 0.587 seconds Preprocessor visited node count: 2489/1000000 Post‐expand include size: 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