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data-country-code="BD" >Bangladesh</option><option value="Barbados" data-country-code="BB" >Barbados</option><option value="Belarus" data-country-code="BY" >Belarus</option><option value="Belgium" data-country-code="BE" >Belgium</option><option value="Belize" data-country-code="BZ" >Belize</option><option value="Benin" data-country-code="BJ" >Benin</option><option value="Bermuda" data-country-code="BM" >Bermuda</option><option value="Bhutan" data-country-code="BT" >Bhutan</option><option value="Bolivia" data-country-code="BO" >Bolivia</option><option value="Bosnia and Herzegovina" data-country-code="BA" >Bosnia and Herzegovina</option><option value="Botswana" data-country-code="BW" >Botswana</option><option value="Bouvet Island" data-country-code="BV" >Bouvet Island</option><option value="Brazil" data-country-code="BR" >Brazil</option><option value="British Indian Ocean Territory" data-country-code="IO" >British Indian Ocean Territory</option><option value="Brunei" data-country-code="BN" >Brunei</option><option value="Bulgaria" data-country-code="BG" >Bulgaria</option><option value="Burkina Faso" data-country-code="BF" >Burkina Faso</option><option value="Burundi" data-country-code="BI" >Burundi</option><option value="Cambodia" data-country-code="KH" >Cambodia</option><option value="Cameroon" data-country-code="CM" >Cameroon</option><option value="Canada" data-country-code="CA" >Canada</option><option value="Cabo Verde" data-country-code="CV" >Cabo Verde</option><option value="Cayman Islands" data-country-code="KY" >Cayman Islands</option><option value="Central African Republic" data-country-code="CF" >Central African Republic</option><option value="Chad" data-country-code="TD" >Chad</option><option value="Chile" data-country-code="CL" >Chile</option><option value="China, People's Republic of" data-country-code="CN" >China, People's Republic of</option><option value="Christmas Island" data-country-code="CX" >Christmas Island</option><option value="Cocos Islands" data-country-code="CC" >Cocos Islands</option><option value="Colombia" data-country-code="CO" >Colombia</option><option value="Comoros" data-country-code="KM" >Comoros</option><option value="Congo, Democratic Republic of the" data-country-code="CD" >Congo, Democratic Republic of the</option><option value="Congo, Republic of the" data-country-code="CG" >Congo, Republic of the</option><option value="Cook Islands" data-country-code="CK" >Cook Islands</option><option value="Costa Rica" data-country-code="CR" >Costa Rica</option><option value="Côte d'Ivoire" data-country-code="CI" >Côte d'Ivoire</option><option value="Croatia" data-country-code="HR" >Croatia</option><option value="Cuba" data-country-code="CU" >Cuba</option><option value="Curaçao" data-country-code="CW" >Curaçao</option><option value="Cyprus" data-country-code="CY" >Cyprus</option><option value="Czech Republic" data-country-code="CZ" >Czech Republic</option><option value="Denmark" data-country-code="DK" >Denmark</option><option value="Djibouti" data-country-code="DJ" >Djibouti</option><option value="Dominica" data-country-code="DM" >Dominica</option><option value="Dominican Republic" data-country-code="DO" >Dominican Republic</option><option value="East Timor" data-country-code="TL" >East Timor</option><option value="Ecuador" data-country-code="EC" >Ecuador</option><option value="Egypt" data-country-code="EG" >Egypt</option><option value="El Salvador" data-country-code="SV" >El Salvador</option><option value="Equatorial Guinea" data-country-code="GQ" >Equatorial Guinea</option><option value="Eritrea" data-country-code="ER" >Eritrea</option><option value="Estonia" data-country-code="EE" >Estonia</option><option value="Ethiopia" data-country-code="ET" >Ethiopia</option><option value="Falkland Islands" data-country-code="FK" >Falkland Islands</option><option value="Faroe Islands" data-country-code="FO" >Faroe Islands</option><option value="Fiji" data-country-code="FJ" >Fiji</option><option value="Finland" data-country-code="FI" >Finland</option><option value="France" data-country-code="FR" >France</option><option value="France, Metropolitan" data-country-code="FX" >France, Metropolitan</option><option value="French Guiana" data-country-code="GF" >French Guiana</option><option value="French Polynesia" data-country-code="PF" >French Polynesia</option><option value="French South Territories" data-country-code="TF" >French South Territories</option><option value="Gabon" data-country-code="GA" >Gabon</option><option value="Gambia" data-country-code="GM" >Gambia</option><option value="Georgia" data-country-code="GE" >Georgia</option><option value="Germany" data-country-code="DE" >Germany</option><option value="Guernsey" data-country-code="GG" >Guernsey</option><option value="Ghana" data-country-code="GH" >Ghana</option><option value="Gibraltar" data-country-code="GI" >Gibraltar</option><option value="Greece" data-country-code="GR" >Greece</option><option value="Greenland" data-country-code="GL" >Greenland</option><option value="Grenada" data-country-code="GD" >Grenada</option><option value="Guadeloupe" data-country-code="GP" >Guadeloupe</option><option value="Guam" data-country-code="GU" >Guam</option><option value="Guatemala" data-country-code="GT" >Guatemala</option><option value="Guinea" data-country-code="GN" >Guinea</option><option value="Guinea-Bissau" data-country-code="GW" >Guinea-Bissau</option><option value="Guyana" data-country-code="GY" >Guyana</option><option value="Haiti" data-country-code="HT" >Haiti</option><option value="Heard Island And Mcdonald Island" data-country-code="HM" >Heard Island And Mcdonald Island</option><option value="Honduras" data-country-code="HN" >Honduras</option><option value="Hong Kong" data-country-code="HK" >Hong Kong</option><option value="Hungary" data-country-code="HU" >Hungary</option><option value="Iceland" data-country-code="IS" >Iceland</option><option value="India" data-country-code="IN" >India</option><option value="Indonesia" data-country-code="ID" >Indonesia</option><option value="Iran" data-country-code="IR" >Iran</option><option value="Iraq" data-country-code="IQ" >Iraq</option><option value="Ireland" data-country-code="IE" >Ireland</option><option value="Israel" data-country-code="IL" >Israel</option><option value="Italy" data-country-code="IT" >Italy</option><option value="Jamaica" data-country-code="JM" >Jamaica</option><option value="Japan" data-country-code="JP" >Japan</option><option value="Jersey" data-country-code="JE" >Jersey</option><option value="Johnston Island" data-country-code="JT" >Johnston Island</option><option value="Jordan" data-country-code="JO" >Jordan</option><option value="Kazakhstan" data-country-code="KZ" >Kazakhstan</option><option value="Kenya" data-country-code="KE" >Kenya</option><option value="Kiribati" data-country-code="KI" >Kiribati</option><option value="Korea, Democratic People's Republic of" data-country-code="KP" >Korea, Democratic People's Republic of</option><option value="Korea, Republic of" data-country-code="KR" >Korea, Republic of</option><option value="Kosovo" data-country-code="XK" >Kosovo</option><option value="Kuwait" data-country-code="KW" >Kuwait</option><option value="Kyrgyzstan" data-country-code="KG" >Kyrgyzstan</option><option value="Lao People's Democratic Republic" data-country-code="LA" >Lao People's Democratic Republic</option><option value="Latvia" data-country-code="LV" >Latvia</option><option value="Lebanon" data-country-code="LB" >Lebanon</option><option value="Lesotho" data-country-code="LS" >Lesotho</option><option value="Liberia" data-country-code="LR" >Liberia</option><option value="Libya" data-country-code="LY" >Libya</option><option value="Liechtenstein" data-country-code="LI" >Liechtenstein</option><option value="Lithuania" data-country-code="LT" >Lithuania</option><option value="Luxembourg" data-country-code="LU" >Luxembourg</option><option value="Macau" data-country-code="MO" >Macau</option><option value="North Macedonia" data-country-code="MK" >North Macedonia</option><option value="Madagascar" data-country-code="MG" >Madagascar</option><option value="Malawi" data-country-code="MW" >Malawi</option><option value="Malaysia" data-country-code="MY" >Malaysia</option><option value="Maldives" data-country-code="MV" >Maldives</option><option value="Mali" data-country-code="ML" >Mali</option><option value="Malta" data-country-code="MT" >Malta</option><option value="Marshall Islands" data-country-code="MH" >Marshall Islands</option><option value="Martinique" data-country-code="MQ" >Martinique</option><option value="Mauritania" data-country-code="MR" >Mauritania</option><option value="Mauritius" data-country-code="MU" >Mauritius</option><option value="Mayotte" data-country-code="YT" >Mayotte</option><option value="Mexico" data-country-code="MX" >Mexico</option><option value="Micronesia" data-country-code="FM" >Micronesia</option><option value="Moldova" data-country-code="MD" >Moldova</option><option value="Monaco" data-country-code="MC" >Monaco</option><option value="Mongolia" data-country-code="MN" >Mongolia</option><option value="Montserrat" data-country-code="MS" >Montserrat</option><option value="Montenegro" data-country-code="ME" >Montenegro</option><option value="Morocco" data-country-code="MA" >Morocco</option><option value="Mozambique" data-country-code="MZ" >Mozambique</option><option value="Myanmar" data-country-code="MM" >Myanmar</option><option value="Namibia" data-country-code="NA" >Namibia</option><option value="Nauru" data-country-code="NR" >Nauru</option><option value="Nepal" data-country-code="NP" >Nepal</option><option value="Netherlands" data-country-code="NL" >Netherlands</option><option value="Netherlands Antilles" data-country-code="AN" >Netherlands Antilles</option><option value="New Caledonia" data-country-code="NC" >New Caledonia</option><option value="New Zealand" data-country-code="NZ" >New Zealand</option><option value="Nicaragua" data-country-code="NI" >Nicaragua</option><option value="Niger" data-country-code="NE" >Niger</option><option value="Nigeria" data-country-code="NG" >Nigeria</option><option value="Niue" data-country-code="NU" >Niue</option><option value="Norfolk Island" data-country-code="NF" >Norfolk Island</option><option value="Northern Mariana Islands" data-country-code="MP" >Northern Mariana Islands</option><option value="Norway" data-country-code="NO" >Norway</option><option value="Oman" data-country-code="OM" >Oman</option><option value="Pakistan" data-country-code="PK" >Pakistan</option><option value="Palau" data-country-code="PW" >Palau</option><option value="Palestine, State of" data-country-code="PS" >Palestine, State of</option><option value="Panama" data-country-code="PA" >Panama</option><option value="Papua New Guinea" data-country-code="PG" >Papua New Guinea</option><option value="Paraguay" data-country-code="PY" >Paraguay</option><option value="Peru" data-country-code="PE" >Peru</option><option value="Philippines" data-country-code="PH" >Philippines</option><option value="Pitcairn Islands" data-country-code="PN" >Pitcairn Islands</option><option value="Poland" data-country-code="PL" >Poland</option><option value="Portugal" data-country-code="PT" >Portugal</option><option value="Puerto Rico" data-country-code="PR" >Puerto Rico</option><option value="Qatar" data-country-code="QA" >Qatar</option><option value="Reunion Island" data-country-code="RE" >Reunion Island</option><option value="Romania" data-country-code="RO" >Romania</option><option value="Russia" data-country-code="RU" >Russia</option><option value="Rwanda" data-country-code="RW" >Rwanda</option><option value="Saint Kitts and Nevis" data-country-code="KN" >Saint Kitts and Nevis</option><option value="Saint Lucia" data-country-code="LC" >Saint Lucia</option><option value="Saint Vincent and the Grenadines" data-country-code="VC" >Saint Vincent and the Grenadines</option><option value="Samoa" data-country-code="WS" >Samoa</option><option value="Saint Helena" data-country-code="SH" >Saint Helena</option><option value="Saint Pierre & Miquelon" data-country-code="PM" >Saint Pierre & Miquelon</option><option value="San Marino" data-country-code="SM" >San Marino</option><option value="Sao Tome and Principe" data-country-code="ST" >Sao Tome and Principe</option><option value="Saudi Arabia" data-country-code="SA" >Saudi Arabia</option><option value="Senegal" data-country-code="SN" >Senegal</option><option value="Serbia" data-country-code="RS" >Serbia</option><option value="Seychelles" data-country-code="SC" >Seychelles</option><option value="Sierra Leone" data-country-code="SL" >Sierra Leone</option><option value="Singapore" data-country-code="SG" >Singapore</option><option value="Sint Maarten" data-country-code="MF" >Sint Maarten</option><option value="Slovakia" data-country-code="SK" >Slovakia</option><option value="Slovenia" data-country-code="SI" >Slovenia</option><option value="Solomon Islands" data-country-code="SB" >Solomon Islands</option><option value="Somalia" data-country-code="SO" >Somalia</option><option value="South Africa" data-country-code="ZA" >South Africa</option><option value="South Georgia and South Sandwich" data-country-code="GS" >South Georgia and South Sandwich</option><option value="Spain" data-country-code="ES" >Spain</option><option value="Sri Lanka" data-country-code="LK" >Sri Lanka</option><option value="Stateless Persons" data-country-code="XX" >Stateless Persons</option><option value="Sudan" data-country-code="SD" >Sudan</option><option value="Sudan, South" data-country-code="SS" >Sudan, South</option><option value="Suriname" data-country-code="SR" >Suriname</option><option value="Svalbard and Jan Mayen" data-country-code="SJ" >Svalbard and Jan Mayen</option><option value="Swaziland" data-country-code="SZ" >Swaziland</option><option value="Sweden" data-country-code="SE" >Sweden</option><option value="Switzerland" data-country-code="CH" >Switzerland</option><option value="Syria" data-country-code="SY" >Syria</option><option value="Taiwan, Republic of China" data-country-code="TW" >Taiwan, Republic of China</option><option value="Tajikistan" data-country-code="TJ" >Tajikistan</option><option value="Tanzania" data-country-code="TZ" >Tanzania</option><option value="Thailand" data-country-code="TH" >Thailand</option><option value="Togo" data-country-code="TG" >Togo</option><option value="Tokelau" data-country-code="TK" >Tokelau</option><option value="Tonga" data-country-code="TO" >Tonga</option><option value="Trinidad and Tobago" data-country-code="TT" >Trinidad and Tobago</option><option value="Tunisia" data-country-code="TN" >Tunisia</option><option value="Turkey" data-country-code="TR" >Turkey</option><option value="Turkmenistan" data-country-code="TM" >Turkmenistan</option><option value="Turks And Caicos Islands" data-country-code="TC" >Turks And Caicos Islands</option><option value="Tuvalu" data-country-code="TV" >Tuvalu</option><option value="Uganda" data-country-code="UG" >Uganda</option><option value="Ukraine" data-country-code="UA" >Ukraine</option><option value="United Arab Emirates" data-country-code="AE" >United Arab Emirates</option><option value="United Kingdom" data-country-code="GB" >United Kingdom</option><option value="US Minor Outlying Islands" data-country-code="UM" >US Minor Outlying Islands</option><option value="United States of America (USA)" data-country-code="US" >United States of America (USA)</option><option value="Uruguay" data-country-code="UY" >Uruguay</option><option value="Uzbekistan" data-country-code="UZ" >Uzbekistan</option><option value="Vanuatu" data-country-code="VU" >Vanuatu</option><option value="Vatican City" data-country-code="VA" >Vatican City</option><option value="Venezuela" data-country-code="VE" >Venezuela</option><option value="Vietnam" data-country-code="VN" >Vietnam</option><option value="Virgin Islands, British" data-country-code="VG" >Virgin Islands, British</option><option value="Virgin Islands, U.S." data-country-code="VI" >Virgin Islands, U.S.</option><option value="Wallis And Futuna Islands" data-country-code="WF" >Wallis And Futuna Islands</option><option value="Western Sahara" data-country-code="EH" >Western Sahara</option><option value="Yemen Arab Rep." data-country-code="YE" >Yemen Arab Rep.</option><option value="Yemen Democratic" data-country-code="YD" >Yemen Democratic</option><option value="Zambia" data-country-code="ZM" >Zambia</option><option value="Zimbabwe" data-country-code="ZW" >Zimbabwe</option></select></div></div></div></div></div><div class="forminator-row"><div id="email-1" class="forminator-col forminator-col-6 "><div class="forminator-field"><label for="forminator-field-email-1_674b3ecbdaf3b" class="forminator-label">Email Address <span class="forminator-required">*</span></label><input type="email" name="email-1" value="" 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heavy drinkers” and that “baclofen may be particularly useful in patients with liver disease,” deserves comment.1 First, Andrade failed to recall that the first pivotal trial of baclofen, ALPADIR (NCT01738282; 320 patients, as with Bacloville), was negative (see Braillon et al2). Second, Dr Andrade should have warned readers that Bacloville’s results are most questionable, lacking robustness. Although he cited us,3 he overlooked the evidence we provided indicating that the Bacloville article4 was published without acknowledging major changes to the initial protocol, affecting the primary outcome. Coincidentally (although as skeptics, we do not believe in coincidence), the initial statistical team was changed when data were sold to the French pharmaceutical company applying for the marketing authorization in France. As Ronald H. Coase warned, “If you torture the data long enough, it will confess.” </div> </div> </div> </div>   <div class="modal fade" id="related_articles_modal" tabindex="-1" role="dialog" aria-labelledby="exampleModalCenterTitle" aria-hidden="true"> <div class="modal-dialog modal-dialog-centered" role="document"> <div class="modal-content"> <div class="modal-header"> <h5 class="modal-title" id="exampleModalLongTitle">Related Articles</h5> <button type="button" class="close" data-dismiss="modal" aria-label="Close"> <span aria-hidden="true">×</span> </button> </div> <div class="modal-body"> <div id="trendmd-suggestions"></div> </div> <div class="modal-footer"> <button type="button" class="btn btn-secondary" data-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="modal fade" id="toc_articles_modal" tabindex="-1" role="dialog" aria-labelledby="exampleModalCenterTitle" aria-hidden="true"> <div class="modal-dialog modal-dialog-centered" role="document"> <div class="modal-content"> <div class="modal-header"> <h5 class="modal-title" id="exampleModalLongTitle">Table Of Contents</h5> <button type="button" class="close" data-dismiss="modal" aria-label="Close"> <span aria-hidden="true">×</span> </button> </div> <div class="modal-body"> <div id="sections"></div> </div> <div class="modal-footer"> <button type="button" class="btn btn-secondary" data-dismiss="modal">Close</button> </div> </div> </div> </div> <div class="wordpress_loader" id="JCP_loader" style="display:none;"></div> <script type="text/javascript"> (function () { var c = document.body.className; 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