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data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above">calcium channel, voltage-dependent, P/Q type, alpha 1A subunit</th></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifiers</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Symbol</th><td class="infobox-data" style="background-color: #eee">CACNA1A</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Alt. symbols</th><td class="infobox-data" style="background-color: #eee">CACNL1A4, SCA6, MHP1, MHP</td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/International_Union_of_Basic_and_Clinical_Pharmacology" title="International Union of Basic and Clinical Pharmacology">IUPHAR</a></th><td class="infobox-data" style="background-color: #eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=532">532</a></span></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/National_Center_for_Biotechnology_Information#Gene" title="National Center for Biotechnology Information">NCBI gene</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&list_uids=773&rn=1">773</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/HUGO_Gene_Nomenclature_Committee" title="HUGO Gene Nomenclature Committee">HGNC</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1388">1388</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://omim.org/entry/601011">601011</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/RefSeq" title="RefSeq">RefSeq</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/protein/NM_000068">NM_000068</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Swiss-Prot" class="mw-redirect" title="Swiss-Prot">UniProt</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/O00555">O00555</a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Other data</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Locus</a></th><td class="infobox-data" style="background-color: #eee"><a href="/wiki/Chromosome_19_(human)" class="mw-redirect" title="Chromosome 19 (human)">Chr. 19</a> <i><a rel="nofollow" class="external text" href="https://omim.org/search/?index=geneMap&search=19p13">p13</a></i></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><table class="infobox mw-collapsible mw-collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Search for</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Structures</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://swissmodel.expasy.org/repository/uniprot/O00555">Swiss-model</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;">Domains</th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/interpro/protein/O00555">InterPro</a></td></tr></tbody></table></td></tr></tbody></table> <p>The <b>Q-type calcium channel</b> is a type of <a href="/wiki/Voltage-dependent_calcium_channel" class="mw-redirect" title="Voltage-dependent calcium channel">voltage-dependent calcium channel</a>. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties. </p><p>They are poorly understood, but like <a href="/wiki/R-type_calcium_channel" title="R-type calcium channel">R-type calcium channels</a>, they appear to be present in <a href="/wiki/Cerebellum" title="Cerebellum">cerebellar</a> granule cells. They have a high threshold of activation and relatively slow kinetics. </p> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Q-type_calcium_channel&action=edit&section=1" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=Q-Type+Calcium+Channel">Q-Type+Calcium+Channel</a> at the U.S. National Library of Medicine <a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">Medical Subject Headings</a> (MeSH)</li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist 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.navbar-boxtext{word-spacing:0}.mw-parser-output .navbar ul{display:inline-block;white-space:nowrap;line-height:inherit}.mw-parser-output .navbar-brackets::before{margin-right:-0.125em;content:"[ "}.mw-parser-output .navbar-brackets::after{margin-left:-0.125em;content:" ]"}.mw-parser-output .navbar li{word-spacing:-0.125em}.mw-parser-output .navbar a>span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}html.skin-theme-clientpref-night .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}@media(prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .navbar li a abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Ion_channels" title="Template:Ion channels"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Ion_channels" title="Template talk:Ion channels"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Ion_channels" title="Special:EditPage/Template:Ion channels"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Membrane_transport_protein:_ion_channels_(TC_1A)" style="font-size:114%;margin:0 4em"><a href="/wiki/Membrane_transport_protein" title="Membrane transport protein">Membrane transport protein</a>: <a href="/wiki/Ion_channel" title="Ion channel">ion channels</a> (<a href="/wiki/Transporter_Classification_Database#1._Channels/Pores" title="Transporter Classification Database">TC 1A</a>)</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible uncollapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background-color: AntiqueWhite;"><div id="Ca2+:_Calcium_channel" style="font-size:114%;margin:0 4em"><i>Ca<sup>2+</sup>:</i> <a href="/wiki/Calcium_channel" title="Calcium channel">Calcium channel</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;background:transparent;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;">Ligand-gated</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Inositol_trisphosphate_receptor" title="Inositol trisphosphate receptor">Inositol trisphosphate receptor</a> <ul><li><a href="/wiki/ITPR1" title="ITPR1">1</a></li> <li><a href="/wiki/ITPR2" title="ITPR2">2</a></li> <li><a href="/wiki/ITPR3" title="ITPR3">3</a></li></ul></li> <li><a href="/wiki/Ryanodine_receptor" title="Ryanodine receptor">Ryanodine receptor</a> <ul><li><a href="/wiki/RYR1" class="mw-redirect" title="RYR1">1</a></li> <li><a href="/wiki/Ryanodine_receptor_2" title="Ryanodine receptor 2">2</a></li> <li><a href="/wiki/RYR3" class="mw-redirect" title="RYR3">3</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><a href="/wiki/Voltage-gated_calcium_channel" title="Voltage-gated calcium channel">Voltage-gated</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/L-type_calcium_channel" title="L-type calcium channel">L-type</a>/<i>Ca<sub>v</sub>α</i> <ul><li><a href="/wiki/Cav1.1" title="Cav1.1">1.1</a></li> <li><a href="/wiki/Cav1.2" title="Cav1.2">1.2</a></li> <li><a href="/wiki/Cav1.3" title="Cav1.3">1.3</a></li> <li><a href="/wiki/Cav1.4" title="Cav1.4">1.4</a></li></ul></li> <li><a href="/wiki/N-type_calcium_channel" title="N-type calcium channel">N-type</a>/<i>Ca<sub>v</sub>α2.2</i></li> <li><a href="/wiki/P-type_calcium_channel" title="P-type calcium channel">P-type</a>/<i>Ca<sub>v</sub>α</i> <ul><li><a href="/wiki/Cav2.1" title="Cav2.1">2.1</a></li></ul></li> <li><a class="mw-selflink selflink">Q-type</a>/<i>Ca<sub>v</sub>α2.1</i></li> <li><a href="/wiki/R-type_calcium_channel" title="R-type calcium channel">R-type</a>/<i>Ca<sub>v</sub>α2.3</i></li> <li><a href="/wiki/T-type_calcium_channel" title="T-type calcium channel">T-type</a>/<i>Ca<sub>v</sub>α</i> <ul><li><a href="/wiki/CACNA1G" title="CACNA1G">3.1</a></li> <li><a href="/wiki/CACNA1H" class="mw-redirect" title="CACNA1H">3.2</a></li> <li><a href="/wiki/CACNA1I" title="CACNA1I">3.3</a></li></ul></li></ul> <ul><li><i>α<sub>2</sub>δ-subunits</i> <ul><li><a href="/wiki/CACNA2D1" title="CACNA2D1">1</a></li> <li><a href="/wiki/CACNA2D2" title="CACNA2D2">2</a></li></ul></li> <li><i>β-subunits</i> <ul><li><a href="/wiki/CACNB1" title="CACNB1">β1</a></li> <li><a href="/wiki/CACNB2" title="CACNB2">β2</a></li> <li><a href="/wiki/CACNB3" title="CACNB3">β3</a></li> <li><a href="/wiki/CACNB4" title="CACNB4">β4</a></li></ul></li> <li><i>γ-subunits</i> <ul><li><a href="/wiki/CACNG1" title="CACNG1">γ1</a></li> <li><a href="/wiki/CACNG2" title="CACNG2">γ2</a></li> <li><a href="/wiki/CACNG3" title="CACNG3">γ3</a></li> <li><a href="/wiki/CACNG4" title="CACNG4">γ4</a></li></ul></li></ul> <ul><li><a href="/wiki/Cation_channels_of_sperm" title="Cation channels of sperm">Cation channels of sperm</a> <ul><li><a href="/wiki/CatSper1" title="CatSper1">1</a></li> <li><a href="/wiki/CatSper2" title="CatSper2">2</a></li> <li><a href="/wiki/CatSper3" title="CatSper3">3</a></li> <li><a href="/wiki/CatSper4" title="CatSper4">4</a></li></ul></li> <li><a href="/wiki/Two-pore_channel" title="Two-pore channel">Two-pore channel</a> <ul><li><a href="/wiki/TPCN1" title="TPCN1">1</a></li> <li><a href="/wiki/TPCN2" title="TPCN2">2</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background-color: AntiqueWhite;"><div id="Na+:_Sodium_channel" style="font-size:114%;margin:0 4em"><i>Na<sup>+</sup>:</i> <a href="/wiki/Sodium_channel" title="Sodium channel">Sodium channel</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;background:transparent;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;">Constitutively active</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Epithelial_sodium_channel" title="Epithelial sodium channel">Epithelial sodium channel</a> <ul><li><a href="/wiki/SCNN1A" title="SCNN1A">α</a></li> <li><a href="/wiki/SCNN1B" title="SCNN1B">β</a></li> <li><a href="/wiki/SCNN1G" title="SCNN1G">γ</a></li> <li><a href="/wiki/SCNN1D" title="SCNN1D">δ</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><a href="/wiki/Hydron_(chemistry)" title="Hydron (chemistry)">Proton</a>-gated</th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Acid-sensing_ion_channel" title="Acid-sensing ion channel">Amiloride-sensitive cation channel</a> <ul><li><a href="/wiki/ACCN1" class="mw-redirect" title="ACCN1">1</a></li> <li><a href="/wiki/ACCN2" class="mw-redirect" title="ACCN2">2</a></li> <li><a href="/wiki/ACCN3" class="mw-redirect" title="ACCN3">3</a></li> <li><a href="/wiki/ACCN4" class="mw-redirect" title="ACCN4">4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><a href="/wiki/Voltage-gated_sodium_channel" title="Voltage-gated sodium channel">Voltage-gated</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><i>Na<sub>v</sub>α</i> <ul><li><a href="/wiki/Nav1.1" class="mw-redirect" title="Nav1.1">1.1</a></li> <li><a href="/wiki/Nav1.2" class="mw-redirect" title="Nav1.2">1.2</a></li> <li><a href="/wiki/SCN3A" title="SCN3A">1.3</a></li> <li><a href="/wiki/Nav1.4" title="Nav1.4">1.4</a></li> <li><a href="/wiki/Nav1.5" class="mw-redirect" title="Nav1.5">1.5</a></li> <li><a href="/wiki/SCN8A" title="SCN8A">1.6</a></li> <li><a href="/wiki/Nav1.7" class="mw-redirect" title="Nav1.7">1.7</a></li> <li><a href="/wiki/SCN10A" class="mw-redirect" title="SCN10A">1.8</a></li> <li><a href="/wiki/Nav1.9" title="Nav1.9">1.9</a></li> <li><a href="/wiki/SCN7A" title="SCN7A">7A</a></li></ul></li> <li><i>Na<sub>v</sub>β</i> <ul><li><a href="/wiki/SCN1B" title="SCN1B">1</a></li> <li><a href="/wiki/SCN2B" title="SCN2B">2</a></li> <li><a href="/wiki/SCN3B" title="SCN3B">3</a></li> <li><a href="/wiki/SCN4B" title="SCN4B">4</a></li></ul></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background-color: AntiqueWhite;"><div id="K+:_Potassium_channel" style="font-size:114%;margin:0 4em"><i>K<sup>+</sup>:</i> <a href="/wiki/Potassium_channel" title="Potassium channel">Potassium channel</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;background:transparent;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><a href="/wiki/Calcium-activated_potassium_channel" title="Calcium-activated potassium channel">Calcium-activated</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/BK_channel" title="BK channel">BK channel</a> <ul><li><a href="/wiki/Calcium-activated_potassium_channel_subunit_alpha-1" title="Calcium-activated potassium channel subunit alpha-1">α1</a></li> <li><a href="/wiki/KCNMB1" title="KCNMB1">β1</a></li> <li><a href="/wiki/KCNMB2" title="KCNMB2">β2</a></li> <li><a href="/wiki/KCNMB3" title="KCNMB3">β3</a></li> <li><a href="/wiki/KCNMB4" title="KCNMB4">β4</a></li></ul></li> <li><a href="/wiki/SK_channel" title="SK channel">SK channel</a> <ul><li><a href="/wiki/KCNN1" title="KCNN1">SK1</a></li> <li><a href="/wiki/KCNN2" title="KCNN2">SK2</a></li> <li><a href="/wiki/SK3" title="SK3">SK3</a></li></ul></li> <li>IK channel <ul><li><a href="/wiki/KCNN4" title="KCNN4">IK1</a></li></ul></li> <li><i>K<sub>Ca</sub></i> <ul><li><a href="/wiki/Calcium-activated_potassium_channel_subunit_alpha-1" title="Calcium-activated potassium channel subunit alpha-1">1.1</a></li> <li><a href="/wiki/KCNN1" title="KCNN1">2.1</a></li> <li><a href="/wiki/KCNN2" title="KCNN2">2.2</a></li> <li><a href="/wiki/SK3" title="SK3">2.3</a></li> <li><a href="/wiki/KCNN4" title="KCNN4">3.1</a></li> <li><a href="/wiki/KCNT1" title="KCNT1">4.1</a></li> <li><a href="/wiki/KCNT2" title="KCNT2">4.2</a></li> <li><a href="/wiki/KCNU1" title="KCNU1">5.1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><a href="/wiki/Inward-rectifier_potassium_ion_channel" class="mw-redirect" title="Inward-rectifier potassium ion channel">Inward-rectifier</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ATP-sensitive_potassium_channel" title="ATP-sensitive potassium channel">K<sub>ATP</sub></a></li> <li><i>K<sub>ir</sub></i> <ul><li><a href="/wiki/ROMK" title="ROMK">1.1</a></li> <li><a href="/wiki/Kir2.1" title="Kir2.1">2.1</a></li> <li><a href="/wiki/KCNJ12" title="KCNJ12">2.2</a></li> <li><a href="/wiki/KCNJ4" title="KCNJ4">2.3</a></li> <li><a href="/wiki/KCNJ14" title="KCNJ14">2.4</a></li> <li><a href="/wiki/Kir2.6" title="Kir2.6">2.6</a></li></ul></li> <li><a href="/wiki/G_protein-coupled_inwardly_rectifying_potassium_channel" title="G protein-coupled inwardly rectifying potassium channel">GIRK</a>/<i>K<sub>ir</sub></i> <ul><li><a href="/wiki/KCNJ3" title="KCNJ3">3.1</a></li> <li><a href="/wiki/KCNJ6" title="KCNJ6">3.2</a></li> <li><a href="/wiki/KCNJ9" title="KCNJ9">3.3</a></li> <li><a href="/wiki/KCNJ5" title="KCNJ5">3.4</a></li></ul></li> <li><i>K<sub>ir</sub></i> <ul><li><a href="/wiki/KCNJ10" title="KCNJ10">4.1</a></li> <li><a href="/wiki/KCNJ15" title="KCNJ15">4.2</a></li> <li><a href="/wiki/KCNJ16" title="KCNJ16">5.1</a></li> <li><a href="/wiki/KCNJ8" title="KCNJ8">6.1</a></li> <li><a href="/wiki/Kir6.2" title="Kir6.2">6.2</a></li> <li><a href="/wiki/KCNJ13" title="KCNJ13">7.1</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><a href="/wiki/Tandem_pore_domain_potassium_channel" class="mw-redirect" title="Tandem pore domain potassium channel">Tandem pore domain</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><i>K2P</i> <ul><li><a href="/wiki/KCNK1" title="KCNK1">1</a></li> <li><a href="/wiki/KCNK2" title="KCNK2">2</a></li> <li><a href="/wiki/KCNK3" title="KCNK3">3</a></li> <li><a href="/wiki/KCNK4" title="KCNK4">4</a></li> <li><a href="/wiki/KCNK5" title="KCNK5">5</a></li> <li><a href="/wiki/KCNK6" title="KCNK6">6</a></li> <li><a href="/wiki/KCNK7" title="KCNK7">7</a></li> <li><a href="/wiki/KCNK9" title="KCNK9">9</a></li> <li><a href="/wiki/KCNK10" title="KCNK10">10</a></li> <li><a href="/wiki/KCNK12" title="KCNK12">12</a></li> <li><a href="/wiki/KCNK13" title="KCNK13">13</a></li> <li><a href="/wiki/KCNK15" title="KCNK15">15</a></li> <li><a href="/wiki/KCNK16" title="KCNK16">16</a></li> <li><a href="/wiki/KCNK17" title="KCNK17">17</a></li> <li><a href="/wiki/KCNK18" title="KCNK18">18</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><a href="/wiki/Voltage-gated_potassium_channel" title="Voltage-gated potassium channel">Voltage-gated</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><i>K<sub>v</sub>α1-6</i> <ul><li><a href="/wiki/Kv1.1" title="Kv1.1">1.1</a></li> <li><a href="/wiki/KCNA2" title="KCNA2">1.2</a></li> <li><a href="/wiki/KCNA3" title="KCNA3">1.3</a></li> <li><a href="/wiki/KCNA4" title="KCNA4">1.4</a></li> <li><a href="/wiki/KCNA5" title="KCNA5">1.5</a></li> <li><a href="/wiki/KCNA6" title="KCNA6">1.6</a></li> <li><a href="/wiki/KCNA7" title="KCNA7">1.7</a></li> <li><a href="/wiki/KCNA10" title="KCNA10">1.8</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNB1" title="KCNB1">2.1</a></li> <li><a href="/wiki/KCNB2" title="KCNB2">2.2</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNC1" title="KCNC1">3.1</a></li> <li><a href="/wiki/KCNC2" title="KCNC2">3.2</a></li> <li><a href="/wiki/KCNC3" title="KCNC3">3.3</a></li> <li><a href="/wiki/KCNC4" title="KCNC4">3.4</a></li></ul></li> <li> <ul><li><a href="/wiki/KCND1" title="KCND1">4.1</a></li> <li><a href="/wiki/KCND2" title="KCND2">4.2</a></li> <li><a href="/wiki/KCND3" title="KCND3">4.3</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNF1" title="KCNF1">5.1</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNG1" title="KCNG1">6.1</a></li> <li><a href="/wiki/KCNG2" title="KCNG2">6.2</a></li> <li><a href="/wiki/KCNG3" title="KCNG3">6.3</a></li> <li><a href="/wiki/KCNG4" title="KCNG4">6.4</a></li></ul></li></ul> <ul><li><i>K<sub>v</sub>α7-12</i> <ul><li><a href="/wiki/KvLQT1" title="KvLQT1">7.1</a></li> <li><a href="/wiki/KvLQT2" title="KvLQT2">7.2</a></li> <li><a href="/wiki/KvLQT3" title="KvLQT3">7.3</a></li> <li><a href="/wiki/KCNQ4" title="KCNQ4">7.4</a></li> <li><a href="/wiki/KCNQ5" title="KCNQ5">7.5</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNV1" title="KCNV1">8.1</a></li> <li><a href="/wiki/KCNV2" title="KCNV2">8.2</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNS1" title="KCNS1">9.1</a></li> <li><a href="/wiki/KCNS2" title="KCNS2">9.2</a></li> <li><a href="/wiki/KCNS3" title="KCNS3">9.3</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNH1" title="KCNH1">10.1</a></li> <li><a href="/wiki/KCNH5" title="KCNH5">10.2</a></li></ul></li> <li> <ul><li><a href="/wiki/HERG" title="HERG">11.1/hERG</a></li> <li><a href="/wiki/KCNH6" title="KCNH6">11.2</a></li> <li><a href="/wiki/KCNH7" title="KCNH7">11.3</a></li></ul></li> <li> <ul><li><a href="/wiki/KCNH8" title="KCNH8">12.1</a></li> <li><a href="/wiki/KCNH3" title="KCNH3">12.2</a></li> <li><a href="/wiki/KCNH4" title="KCNH4">12.3</a></li></ul></li></ul> <ul><li><i>K<sub>v</sub>β</i> <ul><li><a href="/wiki/KCNAB1" title="KCNAB1">1</a></li> <li><a href="/wiki/KCNAB2" title="KCNAB2">2</a></li> <li><a href="/wiki/KCNAB3" title="KCNAB3">3</a></li></ul></li> <li><i>KCNIP</i> <ul><li><a href="/wiki/KCNIP1" title="KCNIP1">1</a></li> <li><a href="/wiki/KCNIP2" title="KCNIP2">2</a></li> <li><a href="/wiki/Calsenilin" title="Calsenilin">3</a></li> <li><a href="/wiki/KCNIP4" title="KCNIP4">4</a></li></ul></li> <li><a href="/wiki/KCNE1" title="KCNE1">minK/ISK</a></li> <li><a href="/wiki/KCNE1L" class="mw-redirect" title="KCNE1L">minK/ISK-like</a></li> <li><i>MiRP</i> <ul><li><a href="/wiki/KCNE2" title="KCNE2">1</a></li> <li><a href="/wiki/KCNE3" title="KCNE3">2</a></li> <li><a href="/wiki/KCNE4" title="KCNE4">3</a></li></ul></li> <li><a href="/wiki/Shaker_(gene)" title="Shaker (gene)">Shaker (gene)</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background-color: AntiqueWhite;"><div id="Miscellaneous" style="font-size:114%;margin:0 4em"><i>Miscellaneous</i></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;background:transparent;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><i><a href="/wiki/Chloride" title="Chloride">Cl<sup>−</sup></a>:</i> <a href="/wiki/Chloride_channel" title="Chloride channel">Chloride channel</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Calcium-activated_chloride_channel" class="mw-redirect" title="Calcium-activated chloride channel">Calcium-activated chloride channels</a> <ul><li><i>Anoctamin</i> <ul><li><a href="/wiki/ANO1" title="ANO1">ANO1</a></li></ul></li> <li><i>Bestrophin</i> <ul><li><a href="/wiki/Bestrophin_1" title="Bestrophin 1">1</a></li> <li><a href="/wiki/BEST2" class="mw-redirect" title="BEST2">2</a></li></ul></li> <li><i>Chloride Channel Accessory</i> <ul><li><a href="/wiki/CLCA1" title="CLCA1">1</a></li> <li><a href="/wiki/CLCA2" title="CLCA2">2</a></li> <li><a href="/wiki/CLCA3" title="CLCA3">3</a></li> <li><a href="/wiki/CLCA4" title="CLCA4">4</a></li></ul></li></ul></li> <li><a href="/wiki/Cystic_fibrosis_transmembrane_conductance_regulator" title="Cystic fibrosis transmembrane conductance regulator">CFTR</a></li> <li><i>CLCN</i> <ul><li><a href="/wiki/CLCN1" title="CLCN1">1</a></li> <li><a href="/wiki/CLCN2" title="CLCN2">2</a></li> <li><a href="/wiki/CLCN3" title="CLCN3">3</a></li> <li><a href="/wiki/CLCN4" title="CLCN4">4</a></li> <li><a href="/wiki/CLCN5" title="CLCN5">5</a></li> <li><a href="/wiki/CLCN6" title="CLCN6">6</a></li> <li><a href="/wiki/CLCN7" title="CLCN7">7</a></li> <li><a href="/wiki/CLCNKA" title="CLCNKA">KA</a></li> <li><a href="/wiki/CLCNKB" title="CLCNKB">KB</a></li></ul></li> <li><i>CLIC</i> <ul><li><a href="/wiki/CLIC1" title="CLIC1">1</a></li> <li><a href="/wiki/CLIC2" title="CLIC2">2</a></li> <li><a href="/wiki/CLIC3" title="CLIC3">3</a></li> <li><a href="/wiki/CLIC4" title="CLIC4">4</a></li> <li><a href="/wiki/CLIC5" title="CLIC5">5</a></li> <li><a href="/wiki/CLIC6" title="CLIC6">6</a></li> <li><a href="/wiki/CLCC1" title="CLCC1">L1</a></li></ul></li> <li><i>CLNS</i> <ul><li><a href="/wiki/CLNS1A" title="CLNS1A">1A</a></li> <li><a href="/wiki/CLNS1B" title="CLNS1B">1B</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><i><a href="/wiki/Hydron_(chemistry)" title="Hydron (chemistry)">H<sup>+</sup></a>:</i> <a href="/wiki/Voltage-gated_proton_channel" title="Voltage-gated proton channel">Proton channel</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/HVCN1" title="HVCN1">HVCN1</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><i><a href="/wiki/Ion#Anions_and_cations" title="Ion">M<sup>+</sup></a>:</i> <a href="/wiki/Cyclic_nucleotide-gated_ion_channel" class="mw-redirect" title="Cyclic nucleotide-gated ion channel">CNG cation channel</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><i>α</i> <ul><li><a href="/wiki/Cyclic_nucleotide-gated_channel_alpha_1" title="Cyclic nucleotide-gated channel alpha 1">1</a></li> <li><a href="/wiki/Cyclic_nucleotide-gated_channel_alpha_2" title="Cyclic nucleotide-gated channel alpha 2">2</a></li> <li><a href="/wiki/Cyclic_nucleotide-gated_channel_alpha_3" title="Cyclic nucleotide-gated channel alpha 3">3</a></li> <li><a href="/wiki/Cyclic_nucleotide-gated_channel_alpha_4" title="Cyclic nucleotide-gated channel alpha 4">4</a></li></ul></li> <li><i>β</i> <ul><li><a href="/wiki/CNGB1" title="CNGB1">1</a></li> <li><a href="/wiki/Cyclic_nucleotide-gated_channel_alpha_4" title="Cyclic nucleotide-gated channel alpha 4">2</a></li> <li><a href="/wiki/Cyclic_nucleotide_gated_channel_beta_3" title="Cyclic nucleotide gated channel beta 3">3</a></li></ul></li> <li><i><a href="/wiki/HCN_channel" title="HCN channel">HCN</a></i> <ul><li><a href="/wiki/Funny_current" class="mw-redirect" title="Funny current">FC</a></li> <li><a href="/wiki/HCN1" title="HCN1">1</a></li> <li><a href="/wiki/HCN2" title="HCN2">2</a></li> <li><a href="/wiki/HCN3" title="HCN3">3</a></li> <li><a href="/wiki/HCN4" title="HCN4">4</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><i><a href="/wiki/Ion#Anions_and_cations" title="Ion">M<sup>+</sup></a>:</i> <a href="/wiki/Transient_receptor_potential_channel" title="Transient receptor potential channel">TRP cation channel</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/TRPA_(channel)" class="mw-redirect" title="TRPA (channel)">TRPA</a> (<a href="/wiki/Transient_receptor_potential_cation_channel,_member_A1" class="mw-redirect" title="Transient receptor potential cation channel, member A1">1</a>)</li> <li><a href="/wiki/TRPC" title="TRPC">TRPC</a> <ul><li><a href="/wiki/TRPC1" title="TRPC1">1</a></li> <li><a href="/wiki/TRPC2" title="TRPC2">2</a></li> <li><a href="/wiki/TRPC3" title="TRPC3">3</a></li> <li><a href="/wiki/TRPC4" title="TRPC4">4</a></li> <li><a href="/wiki/TRPC4AP" title="TRPC4AP">4AP</a></li> <li><a href="/wiki/TRPC5" title="TRPC5">5</a></li> <li><a href="/wiki/TRPC6" title="TRPC6">6</a></li> <li><a href="/wiki/TRPC7" title="TRPC7">7</a></li></ul></li> <li><a href="/wiki/TRPM" title="TRPM">TRPM</a> <ul><li><a href="/wiki/TRPM1" title="TRPM1">1</a></li> <li><a href="/wiki/TRPM2" title="TRPM2">2</a></li> <li><a href="/wiki/TRPM3" title="TRPM3">3</a></li> <li><a href="/wiki/TRPM4" title="TRPM4">4</a></li> <li><a href="/wiki/TRPM5" title="TRPM5">5</a></li> <li><a href="/wiki/TRPM6" title="TRPM6">6</a></li> <li><a href="/wiki/TRPM7" title="TRPM7">7</a></li> <li><a href="/wiki/TRPM8" title="TRPM8">8</a></li></ul></li> <li><a href="/wiki/TRPML" title="TRPML">TRPML</a> <ul><li><a href="/wiki/Mucolipin-1" class="mw-redirect" title="Mucolipin-1">1</a></li> <li><a href="/wiki/MCOLN2" title="MCOLN2">2</a></li> <li><a href="/wiki/MCOLN3" title="MCOLN3">3</a></li></ul></li> <li><a href="/wiki/TRPN" title="TRPN">TRPN</a></li> <li><a href="/wiki/TRPP" title="TRPP">TRPP</a> <ul><li><a href="/wiki/PKD1" class="mw-redirect" title="PKD1">1</a></li> <li><a href="/wiki/Polycystic_kidney_disease_2" class="mw-redirect" title="Polycystic kidney disease 2">2</a></li></ul></li> <li><a href="/wiki/TRPV" title="TRPV">TRPV</a> <ul><li><a href="/wiki/TRPV1" title="TRPV1">1</a></li> <li><a href="/wiki/TRPV2" title="TRPV2">2</a></li> <li><a href="/wiki/TRPV3" title="TRPV3">3</a></li> <li><a href="/wiki/TRPV4" title="TRPV4">4</a></li> <li><a href="/wiki/TRPV5" title="TRPV5">5</a></li> <li><a href="/wiki/TRPV6" title="TRPV6">6</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><i><a href="/wiki/Water" title="Water">H<sub>2</sub>O</a> (+ <a href="/wiki/Solutes" class="mw-redirect" title="Solutes">solutes</a>):</i> <a href="/wiki/Porin_(protein)" title="Porin (protein)">Porin</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aquaporin" title="Aquaporin">Aquaporin</a> <ul><li><a href="/wiki/MIP_(gene)" class="mw-redirect" title="MIP (gene)">0</a></li> <li><a href="/wiki/Aquaporin_1" class="mw-redirect" title="Aquaporin 1">1</a></li> <li><a href="/wiki/Aquaporin_2" class="mw-redirect" title="Aquaporin 2">2</a></li> <li><a href="/wiki/Aquaporin_3" class="mw-redirect" title="Aquaporin 3">3</a></li> <li><a href="/wiki/Aquaporin_4" class="mw-redirect" title="Aquaporin 4">4</a></li> <li><a href="/wiki/AQP5" class="mw-redirect" title="AQP5">5</a></li> <li><a href="/wiki/AQP6" class="mw-redirect" title="AQP6">6</a></li> <li><a href="/wiki/AQP7" class="mw-redirect" title="AQP7">7</a></li> <li><a href="/wiki/AQP8" class="mw-redirect" title="AQP8">8</a></li> <li><a href="/wiki/AQP9" class="mw-redirect" title="AQP9">9</a></li></ul></li> <li><a href="/wiki/Voltage-dependent_anion_channel" title="Voltage-dependent anion channel">Voltage-dependent anion channel</a> <ul><li><a href="/wiki/VDAC1" title="VDAC1">1</a></li> <li><a href="/wiki/VDAC2" title="VDAC2">2</a></li> <li><a href="/wiki/VDAC3" title="VDAC3">3</a></li></ul></li> <li><a href="/wiki/General_bacterial_porin_family" title="General bacterial porin family">General bacterial porin family</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:15em;text-align:left;"><i><a href="/wiki/Cytoplasm" title="Cytoplasm">Cytoplasm</a>:</i> <a href="/wiki/Gap_junction" title="Gap junction">Gap junction</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Connexin" title="Connexin">Connexin</a> <ul><li>A <ul><li><a href="/wiki/GJA1" title="GJA1">GJA1</a></li> <li><a href="/wiki/GJA3" title="GJA3">GJA3</a></li> <li><a href="/wiki/GJA4" title="GJA4">GJA4</a></li> <li><a href="/wiki/GJA5" title="GJA5">GJA5</a></li> <li><a href="/wiki/GJA8" title="GJA8">GJA8</a></li> <li><a href="/wiki/GJD2" title="GJD2">GJA9</a></li> <li><a href="/wiki/GJA10" title="GJA10">GJA10</a></li></ul></li> <li>B <ul><li><a href="/wiki/GJB1" title="GJB1">GJB1</a></li> <li><a href="/wiki/GJB2" title="GJB2">GJB2</a></li> <li><a href="/wiki/GJB3" title="GJB3">GJB3</a></li> <li><a href="/wiki/GJB4" title="GJB4">GJB4</a></li> <li><a href="/wiki/GJB5" title="GJB5">GJB5</a></li> <li><a href="/wiki/GJB6" title="GJB6">GJB6</a></li> <li><a href="/wiki/GJB7" title="GJB7">GJB7</a></li></ul></li> <li>C <ul><li><a href="/wiki/GJC1" title="GJC1">GJC1</a></li> <li><a href="/wiki/GJC2" title="GJC2">GJC2</a></li> <li><a href="/wiki/GJC3" title="GJC3">GJC3</a></li></ul></li> <li>D <ul><li><a href="/wiki/GJD2" title="GJD2">GJD2</a></li> <li><a href="/wiki/GJD3" title="GJD3">GJD3</a></li> <li><a href="/wiki/GJD4" title="GJD4">GJD4</a></li></ul></li></ul></li> <li><a href="/wiki/Innexin" title="Innexin">Innexin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background-color: AntiqueWhite;"><div id="By_gating_mechanism" style="font-size:114%;margin:0 4em"><i>By gating mechanism</i></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0;background:transparent;"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Ion_channel_class" scope="row" class="navbox-group" style="width:15em;text-align:left;"><i>Ion channel class</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;background-color: AntiqueWhite;"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Ligand-gated_ion_channel" title="Ligand-gated ion channel">Ligand-gated</a></li> <li><a href="/wiki/Light-gated_ion_channel" title="Light-gated ion channel">Light-gated</a></li> <li><a href="/wiki/Voltage-gated_ion_channel" title="Voltage-gated ion channel">Voltage-gated</a></li> <li><a href="/wiki/Stretch-activated_ion_channel" class="mw-redirect" title="Stretch-activated ion channel">Stretch-activated</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background-color: AntiqueWhite; padding: 0px;"><div><i>see also <a href="/wiki/Template:Channelopathy" title="Template:Channelopathy">disorders</a></i></div></td></tr></tbody></table></div> <p><br /> </p> <style data-mw-deduplicate="TemplateStyles:r1012311289">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span 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