National Center on Sleep Disorders Research

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data-drupal-messages-fallback class="hidden"></div> <div class="responsive-container responsive-container-constrained breadcrumbs-container"><div class="breadcrumbs"><ul> <li class='breadcrumb-home'><a href='/'>Home</a></li><li class='breacrumb-break'>/</li><li class='breadcrumb-grandparent'><a href='/node/80068'>About the NHLBI</a></li><li class='breacrumb-break'>/</li><li class='breadcrumb-grandparent'><a href='/node/86122'>Divisions, Offices and Centers</a></li><li class='breacrumb-break'>/</li><li class='breadcrumb-parent'><a href='/node/80030'><span class='back-to'> < Back To </span>Division of Lung Diseases</a></li><li class='breacrumb-break'>/</li><li class='breadcrumb-current'>National Center on Sleep Disorders Research</li></ul></div></div> <article class="node node--type-division node--view-mode-full" data-title="National Center on Sleep Disorders Research" data-type="division" data-format="" data-audience="" data-campaign="" > <div class="standard"> <div class="field field--name-field-top-texture-banner field--type-list-string field--label-hidden field__item"> <div class="pageBanner"> <div class="banner-new-red-orange"></div> </div> </div> <div class="secondary-grey-background"> <div class="responsive-container responsive-container-constrained"> <div class="content-container-constrained"> <div class="rtFlexContainer"> <div class="rtTitleClassification"> <h1> <span>National Center on Sleep Disorders Research</span> </h1> <div class="field field--name-field-expanding-content field--type-entity-reference-revisions field--label-hidden field__item"><div class="readMoreContainer paragraph paragraph--type--intro-text paragraph--view-mode--default"> <div class="bodytext"> <div class="field field--name-field-introduction field--type-text-long field--label-hidden field__item"><p>The National Center on Sleep Disorders Research (NCSDR) supports research, technology innovation, training, health education, and other activities that advance scientific knowledge of sleep disorders and circadian biology, and that promote sleep health. The NCSDR also coordinates sleep and circadian biology research throughout the National Institutes of Health (NIH) and other Federal agencies. Located within the National Heart, Lung, and Blood Institute, the NCSDR was established by Congress as part of the <a href="https://www.congress.gov/103/bills/s1/BILLS-103s1enr.pdf" rel="noreferrer">NIH Revitalization Act of 1993 (42 USC Sec. 285b-7)</a>. </p> <p>Under that act, the <span style="font-size:11.0pt"><span style="line-height:107%"><span style="font-family:"Calibri",sans-serif"><a href="https://www.nhlbi.nih.gov/about/advisory-and-peer-review-committees/sleep-disorders-research" style="color:#0563c1; text-decoration:underline" rel="noreferrer"><span style="font-size:13.0pt"><span style="line-height:107%"><span style="font-family:"Open Sans",sans-serif">Sleep Disorders Research Advisory Board</span></span></span></a> </span></span></span>(SDRAB) makes recommendations and assists with the development of a comprehensive NIH plan that identifies sleep and circadian research priorities. <a href="/node/92164">Read the 2021 NIH Sleep Research Plan</a>.</p> <p>NIH funds sleep and circadian research through investigator-initiated and Institute-initiated programs. </p> <ul> <li>Learn more about <a href="https://www.nhlbi.nih.gov/grants-and-training/funding-opportunities-and-contacts/sleep-science-disorders" rel="noreferrer">funding opportunities</a> for research on sleep and the circadian biology of sleep disorders.</li> <li>Read about how the NHLBI's <a href="https://www.nhlbi.nih.gov/science/sleep-science-and-sleep-disorders" rel="noreferrer">Sleep Science and Sleep Disorders</a> research is making a difference.</li> <li>Sign up for updates from the NCSDR and the NHLBI through the <a href="https://list.nih.gov/cgi-bin/wa.exe?A0=SLEEPRFA-L" rel="noreferrer">NIH Listserv</a>. </li> </ul> </div> </div> </div> </div> </div> <div class="onThisPage"> <div class="pagenavtitle"> On this page </div> <ul> <li><a href="#related_sfas">Related Scientific Focus Areas</a></li> <li><a href="#relatedreading">Related News and Events</a></li> <li><a href="#contact_us">Contact Us</a></li> </ul> </div> </div> </div> </div> </div> <div class="responsive-container responsive-container-constrained"> <div class="content-container-constrained content-container-margin"> <div class="general-accordion"> <h2 class="accordion-header" id="mission-25941"> <div class="field field--name-field-panel-title field--type-string field--label-hidden field__item">Mission</div> <span class="ui-helper-hidden-accessible"> - National Center on Sleep Disorders Research </span> </h2> <div class="ui-accordion ui-widget ui-helper-reset paragraph paragraph--type--standard-accordion-panelparagraph--view-mode--primary-accordion" > <div class="bodytext"> <div class="field field--name-field-accordion-body field--type-text-long field--label-hidden field__item"><p>The National Center on Sleep Disorders Research (NCSDR) promotes sleep and circadian scientific advances, from laboratory research to clinical practice, to improve scientific knowledge, transform health care, and advance public health and safety and the well-being of the nation.</p><p><img data-entity-uuid="42cb50a8-aa1a-4c5e-b686-9964807dd05c" data-entity-type="file" alt="Infographic on the National Center of Sleep Disorders Mission. See content below image for details." width="1026" height="1026" data-image-style data-src="/sites/default/files/inline-images/31445_NHLBI_NCSDR_MissionGraphic_v09.png" src="/modules/custom/nhlbi_blazy/images/clear.png" class="b-lazy"></p><h3>The NCSDR works toward achieving its mission in the following ways:</h3><ul><li>Advancing scientific knowledge in essential research areas including chronobiology, neurophysiology, gene expression, epigenetics, and proteostatis. </li><li>Transforming health care using chronomedicine, clinical interventions, and patient-centered strategies, including measuring epidemiological risks and risk stratification.</li><li>Advancing well-being by considering the impact of social determinants of health, health disparities, and individual and community-based interventions on health outcomes.</li><li>Improving public health and safety by promoting sleep health awareness and related risk prevention at worksites, schools, housing and in transportation through technologies such as solid-state lighting.</li></ul><p>One enduring strategy the NCSDR uses to achieve this mission is by fostering a strong and diverse workforce.</p></div> </div> <div class="readMoreContainer"> </div> </div> <h2 class="accordion-header" id="what-we-do-922"> <div class="field field--name-field-panel-title field--type-string field--label-hidden field__item">What We Do</div> <span class="ui-helper-hidden-accessible"> - National Center on Sleep Disorders Research </span> </h2> <div class="ui-accordion ui-widget ui-helper-reset paragraph paragraph--type--standard-accordion-panelparagraph--view-mode--primary-accordion" > <div class="bodytext"> <div class="field field--name-field-accordion-body field--type-text-long field--label-hidden field__item"><p><strong>Chronobiology and Ventilatory Control</strong></p><p>The chronobiology and ventilatory control portfolio supports basic and clinical research that explores how circadian science applies to the development, diagnosis, and treatment of heart, lung, blood disorders. The portfolio also includes research  that describes neural and peripheral mechanisms of breathing control, chemoreception, and the integration of breathing with other functions (e.g., coughing and swallowing). Research in this portfolio is performed using a range of approaches, from studying genes (genomics) to conducting clinical trials. The research addresses current public health concerns, such as the role of sleep, circadian regulation, and ventilatory control in maternal morbidity and mortality, opioid use disorder, and obesity.</p><p>Contact: Aaron D. Laposky, Ph.D., <a href="mailto:laposkya@nhlbi.nih.gov" rel="noreferrer"><span>laposkya@nhlbi.nih.gov</span></a></p><hr><p><strong>Neurobiology of Sleep</strong></p><p>The sleep and neurobiology portfolio supports studies on the neurobiological mechanisms of sleep and its disorders, as well as analyses of the diverse influences on these processes. Investigations include explorations of the roles of identified physiological and pathological mechanisms in sleep and the use of genetic and genomic approaches to uncover novel factors affecting sleep. The research also explores the connections between sleep disorders, health disparities, and social determinants of health. This portfolio includes  computational models, animal models, and clinical investigations of the mechanisms of sleep disorders and their consequences. It also includes a variety of training grant mechanisms , particularly institutional training grants (T32) focused on sleep and circadian rhythms.  </p><p>Contact: Lawrence Baizer, Ph.D., <a href="mailto:baizerl@mail.nih.gov" rel="noreferrer"><span>baizerl@mail.nih.gov</span></a></p><hr><p><strong>Prevention and Sleep Health</strong></p><p>The prevention and sleep health portfolio supports research focused on the relationship between healthy sleep and physical health and well-being, and chronic disease prevention. Studies include investigations into modifying sleep-wake patterns and sleep behaviors to improve health across the life span, and social determinants that contribute to sleep health disparities and impact special populations. This portfolio also includes training and career development grant mechanisms, and Small Business Innovation Research and Small Business Technology Transfer (SBIR/STTR) grant mechanisms for innovative research to develop novel devices and interventions that improve healthy sleep and adherence to treatment.</p><p>Contact: Shilpy Dixit, Ph.D., <a href="mailto:shilpy.dixit@nih.gov" rel="noreferrer"><span>shilpy.dixit@nih.gov</span></a></p><hr><p><strong>Sleep Disorders Medicine</strong></p><p>The sleep disorders medicine portfolio supports research on the genetic predisposition, risk factors, pathogenesis, epidemiology, diagnosis, and treatment of sleep and circadian rhythm sleep-wake disorders. This includes research examining the role of sleep in inflammation, cardiometabolic disorders, vascular contributions to cognitive impairment and dementia, and people living with Down syndrome as part of the NIH INCLUDE program. Additionally, this program supports studies using big data analytics, artificial intelligence, and clinical trials to explore sleep and circadian disorders.</p><p>Contact: Alfonso Alfini, Ph.D., <a href="mailto:alfonso.alfini@nih.gov" rel="noreferrer"><span>alfonso.alfini@nih.gov</span></a></p></div> </div> <div class="readMoreContainer"> </div> </div> <h2 class="accordion-header" id="nih-and-inter-agency-coordination-924"> <div class="field field--name-field-panel-title field--type-string field--label-hidden field__item">NIH and Inter-Agency Coordination </div> <span class="ui-helper-hidden-accessible"> - National Center on Sleep Disorders Research </span> </h2> <div class="ui-accordion ui-widget ui-helper-reset paragraph paragraph--type--standard-accordion-panelparagraph--view-mode--primary-accordion" > <div class="bodytext"> <div class="field field--name-field-accordion-body field--type-text-long field--label-hidden field__item"><p>Sleep disorders, circadian biology, and sleep health relate to a multitude of biological systems, health conditions, and medical disciplines. That is why a coordinated and collaborative approach must be used to successfully advance sleep and circadian science, foster technology transfer, expand training, transform health care, and increase dissemination of health information to advance well-being and improve public health and safety.</p><p>The NCSDR serves as the point-of-contact for researchers, professional societies, non-governmental stakeholders (public, private, and nonprofit groups), and other Federal agencies interested in NIH sleep research activities.</p><p>The NCSDR director serves as the Executive Secretary of the <a href="https://www.nhlbi.nih.gov/about/advisory-and-peer-review-committees/sleep-disorders-research" rel="noreferrer">SDRAB</a>, an Advisory Board composed of Members and Ex Officio Members and led by a member-elected chairperson.  </p><p>The NCSDR leads the <a href="https://www.nhlbi.nih.gov/about/divisions/division-lung-diseases/national-center-sleep-disorders-research/trans-NIH-sleep-research-coordinating-committee" rel="noreferrer">NIH-wide Sleep Research Coordinating Committee</a>, a forum to discuss and consider potential opportunities for programmatic coordination of biological and circadian rhythms research and other sleep-related research, training, and health information dissemination. </p><p>The NCSDR fosters the coordination of sleep and circadian research among other Federal agencies, including:</p><ul><li><a href="http://www.census.gov/" rel="noreferrer">Bureau of the Census</a></li><li><a href="http://www.cdc.gov/" rel="noreferrer">Centers for Disease Control and Prevention</a></li><li><a href="http://www.nasa.gov/" rel="noreferrer">National Aeronautics and Space Administration (NASA)</a></li><li><a href="http://www.dot.gov/" rel="noreferrer">National Highway Traffic Safety Administration/U.S. Department of Transportation</a></li><li><a href="http://www.dol.gov/" rel="noreferrer">U.S. Department of Labor</a></li><li><a href="http://www.defenselink.mil/" rel="noreferrer">U.S. Department of Defense</a></li><li><a href="https://www.energy.gov/" rel="noreferrer">U.S. Department of Energy</a></li><li><a href="https://www.hud.gov/" rel="noreferrer">U.S. Department of Housing and Urban Development</a></li><li><a href="http://www.va.gov/" rel="noreferrer">U.S. Department of Veterans Affairs</a></li></ul><p>The NCSDR director and staff meet regularly with sleep and circadian researchers, professional societies, and other stakeholders to gather feedback and offer updates.</p></div> </div> <div class="readMoreContainer"> </div> </div> <h2 class="accordion-header" id="healthcare-provider-resources-925"> <div class="field field--name-field-panel-title field--type-string field--label-hidden field__item">Healthcare Provider Resources </div> <span class="ui-helper-hidden-accessible"> - National Center on Sleep Disorders Research </span> </h2> <div class="ui-accordion ui-widget ui-helper-reset paragraph paragraph--type--standard-accordion-panelparagraph--view-mode--primary-accordion" > <div class="bodytext"> <div class="field field--name-field-accordion-body field--type-text-long field--label-hidden field__item"><p><span>NCSDR works to turn research findings into health information that benefits the public. It does this, in part, by educating healthcare professionals about the results of sleep disorders research and offering resources they can share with their patients and families.</span></p><p><span>The </span><a href="https://catalog.nhlbi.nih.gov/" rel="noreferrer"><span>NHLBI Online Catalog</span></a><span> lists all NHLBI publications and resources for healthcare professionals, including summaries of the latest sleep science and clinical care best practices. It also lists educational materials that help answer patients’ questions about sleep and sleep disorders.</span></p></div> </div> <div class="readMoreContainer"> </div> </div> <h2 class="accordion-header" id="patient-and-public-education-resources-25838"> <div class="field field--name-field-panel-title field--type-string field--label-hidden field__item">Patient and Public Education Resources</div> <span class="ui-helper-hidden-accessible"> - National Center on Sleep Disorders Research </span> </h2> <div class="ui-accordion ui-widget ui-helper-reset paragraph paragraph--type--standard-accordion-panelparagraph--view-mode--primary-accordion" > <div class="bodytext"> <div class="field field--name-field-accordion-body field--type-text-long field--label-hidden field__item"><p>The NHLBI website features health information on sleep-related health topics for patients, caregivers, and the public. To find links to topics such as insomnia, sleep deprivation and deficiency, sleep apnea, narcolepsy, and sleep studies, go to the <a href="https://www.nhlbi.nih.gov/health-topics/education-and-awareness/sleep-health" rel="noreferrer">Sleep Health</a> webpage and click on the Health Topics icon. You can also find there a link to <a href="https://www.nhlbi.nih.gov/health-topics/all-publications-and-resources/your-guide-healthy-sleep" rel="noreferrer">Your Guide to Healthy Sleep</a>, as well as information about participating in a clinical trial.</p></div> </div> <div class="readMoreContainer"> </div> </div> </div> </div> </div> <div class="responsive-container responsive-container-constrained"> <div class="content-container-constrained content-container-margin"> <div class="full-leadership-container pale-blue-darker-white-background bottom-margin"> <h2>Division Leadership</h2> <div class="leadership-container"> <div class="leadership-director-container"> <div class="field field--name-field-director field--type-entity-reference field--label-hidden field__item"> <article class="node node--type-nhlbi-person node--view-mode-list-item"> <div class=" leadership-bioCard "> <div class="flexItemText"> <h2> <div class="field field--name-field-name field--type-string field--label-hidden field__item">Marishka K. Brown, Ph.D.</div> </h2> <h3 class="no-text-transform"> <div class="field field--name-field-employment-title field--type-string field--label-hidden field__item">Director, National Center on Sleep Disorders Research</div> </h3> <div class="field field--name-field-email field--type-email field--label-hidden field__item"><a href="mailto:marishka.brown@nih.gov" rel="noreferrer">marishka.brown@nih.gov</a></div> </div> </div> </article></div> </div> </div> </div> </div> </div> <div class="secondary-grey-background related-scientific-focus-areas-container top-normal-padding"> <div class="responsive-container responsive-container-constrained"> <div class="content-container-margin"> <h2 id="related_sfas">Related Scientific Focus Areas</h2> <div class="field field--name-field-related-sfas field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/science/sleep-science-and-sleep-disorders" hreflang="en">Sleep Science and Sleep Disorders</a></div> <div class="field__item"><a href="/science/lung-diseases" hreflang="en">Lung Diseases</a></div> </div> </div> </div> </div> <a id="relatedreading"></a> <div class="darkRedBackground"> <div class="responsive-container"> <div class="content-container"> <div class="views-element-container"><div class="view view-nhlbi-news-science view-id-nhlbi_news_science view-display-id-block_9 js-view-dom-id-72303aba13ab58059e04ad26d985522a138bd8c7144a24b6cf5cd5b2c02d8480"> <div class="view-content"> <div class="views-row"> <h2><div class="whitesubhead font-size-l"> RELATED NEWS </div></h2> <article class="featured-science-instance-teaser-container node node--type-press-release node--view-mode-featured-science-instance-teaser"> <div class="flexItemImageThird"> <div class="image-and-photocredit-container"> <div class="field field--name-field-hero-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/modules/custom/nhlbi_blazy/images/clear.png" width="768" height="432" alt="older woman laying in bed awake at night" data-src="/sites/default/files/styles/16x9_crop/public/2023-11/short_sleep_postmenopausal_woman-web.jpg?h=931d7884&itok=OTIP5jEg" class="b-lazy image-style-_6x9-crop" /> </div> </div> </div> <div class="flexTextWithImage flexItemText"> <div class="font-size-l bannerdate"> <time datetime="2023-11-13T16:00:00Z" class="datetime"><span>November 13, 2023</span></time> <div class="paddedBar"> | </div> <div class="field field--name-field-article-type field--type-entity-reference field--label-hidden field__item">News Release</div> </div> <div class="herobannertitle" > <a href="/news/2023/chronic-sleep-deficiency-increases-insulin-resistance-women-especially-postmenopausal" rel="bookmark"> <span>Chronic sleep deficiency increases insulin resistance in women, especially postmenopausal women</span> </a> </div> <div class="bodytext"> <div class="field field--name-field-additional-introduction field--type-text-long field--label-hidden field__item"> <h3><em>Findings highlight insufficient sleep as a modifiable risk factor for type 2 diabetes</em></h3><hr><p>Chronic insufficient sleep can increase insulin resistance in otherwise healthy women, with more marked effects in postmenopausal women, according to a study funded by the National Institutes of Health. The findings, published in Diabetes Care, highlight the...</p> </div> </div> </div> </article> </div> </div> </div> </div> </div> </div> </div> <div class="lightBlueBackground"> <div class="responsive-container"> <div class="content-container"> <div class="views-element-container"><div class="view view-nhlbi-news-science view-id-nhlbi_news_science view-display-id-block_10 js-view-dom-id-5d7e3064f6dfb49f685b6a3c94d1c17b007073faae996f90cdcf97c47aad5e26"> <div class="view-content"> <div class="views-row"> <h2><div class="blackstandardsubhead font-size-l"> RELATED EVENT </div></h2> <article class="featured-science-instance-teaser-container node node--type-events node--view-mode-featured-science-instance-teaser"> <div class="flexItemImageThird"> <div class="image-and-photocredit-container"> <div class="field field--name-field-hero-image field--type-image field--label-hidden field__item"> <img loading="lazy" src="/modules/custom/nhlbi_blazy/images/clear.png" width="750" height="422" alt="a group of young researchers look at two digital tablets" data-src="/sites/default/files/styles/16x9_crop/public/2024-12/AdobeStock_873759120_r.jpg?h=912e55a1&itok=O9PNFGCM" class="b-lazy image-style-_6x9-crop" /> </div> </div> </div> <div class="flexTextWithImage flexItemText"> <div class="herobannertitle" > <a href="/events/2024/concept-clinic-how-advance-innovative-lung-and-sleep-therapies-patients-high-unmet" rel="bookmark"> <span>Concept to the Clinic: How to Advance Innovative Lung and Sleep Therapies to Patients with High Unmet Needs</span> </a> </div> <div class="eventdatesLocationType"> <div class="eventDates"> <div class="fa-regular fa-calendar"></div> <div class="startEndDate"> December 17 - 18 , 2024 </div> </div> <span class="eventLocation"> <span class="fa-regular fa-location-dot"></span> <div class="field field--name-field-location field--type-string-long field--label-hidden field__item">Virtual<br /> December 17 9:30 a.m. - 5:15 p.m. ET<br /> December 18 9:30 a.m. - 5:00 p.m. ET</div> </span> </div> The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) is hosting a two-day virtual workshop ti... <div class="full-padded-top"> <a class="viewmorebutton" href="/events/80030"> View more events on Division of Lung Diseases </a> </div> </div> </article> </div> </div> </div> </div> </div> </div> </div> <div class="secondary-grey-background bottom-padding"> <div class="responsive-container responsive-container-constrained"> <div class="content-container-margin"> <h2 id="contact_us">Contact <span>National Center on Sleep Disorders Research</span> </h2> <div class="field field--name-field-contact-methods field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item contact-method-container-postal-mail"> <article class="paragraph paragraph--type--contact-method paragraph--view-mode--default" > <div class=""> <div class="contact-method-card"> <div class="contact-method-label 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