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Relevium secures €4.6m from DTIF for knee osteoarthritis treatment

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class="sharetime"> <span class="icon_time">27 Nov 2024</span> </p> <button class="pelcro-save-button upper" data-key="articles" data-title="Relevium secures €4.6m from DTIF for knee osteoarthritis treatment" data-link="https://www.siliconrepublic.com/start-ups/relevium-medical-funding-knee-osteroarthritis-treatment-research" > <i class="fa fa-spinner fa-spin"></i> <i class="fa fa-bookmark-o"></i> <i class="fa fa-bookmark"></i> <span class="label-holder">Save article</span> </button> </div> <div class="large-8 collapse pullupmobile columns"> <div> <div class="large-11 columns article-body-container"> <div class="featured"> <img width="800" height="600" src="https://www.siliconrepublic.com/wp-content/uploads/2024/11/Relevium-Medical-group-photo.jpeg" class="alignleft wp-post-image" alt="Four people - three women and one man - pose for a photograph in front of a grey-brick building with a red door." itemprop="image" fetchpriority="high" srcset="https://www.siliconrepublic.com/wp-content/uploads/2024/11/Relevium-Medical-group-photo.jpeg 800w, https://www.siliconrepublic.com/wp-content/uploads/2024/11/Relevium-Medical-group-photo-300x225.jpeg 300w, https://www.siliconrepublic.com/wp-content/uploads/2024/11/Relevium-Medical-group-photo-207x155.jpeg 207w, https://www.siliconrepublic.com/wp-content/uploads/2024/11/Relevium-Medical-group-photo-444x333.jpeg 444w" sizes="(max-width: 800px) 100vw, 800px" /> </div> <div class="row collapse"> <div class="large-offset-2 large-10 columns postcontent"> <p class="photocaption">Left to right: Dr Finola Cliffe, COO, HookeBio, Dr Alison Liddy, CEO and co-founder, Relevium Medical, Dr Leo Quinlan, University of Galway and Dr Sahar Avazzadeh, operations lead, Relevium Medical. Image: Martina Regan.</p> <div class="postsinglecontent"> <!--googleon: all--> <div itemprop="articleBody"> <p>Knee osteoarthritis is the fastest-growing cause of disability, due to the obesity epidemic and an ageing population.</p> <p>University of Galway spin-out Relevium Medical has been awarded &euro;4.6m to further develop its knee osteoarthritis treatment.</p> <p>Relevium Medical secured the funding for the RestOAre project, which aims to develop therapies for debilitating chronic pain and disease progression of knee osteoarthritis.</p> <p>The funding was awarded through the Disruptive Technologies Innovation Fund (DTIF), and is the <a href="https://www.siliconrepublic.com/innovation/disruptive-technologies-innovation-fund-seeking-projects" target="_blank" rel="noopener noreferrer">first successful project under the latest DTIF funding call</a>.</p> <p>Knee osteoarthritis is incurable, complex and progressively worsens over time. It is the fastest-growing cause of disability due to an ageing population and the obesity epidemic. Galway said that knee osteoarthritis is often described as the world&#8217;s largest hidden disability, with 250m sufferers globally, a figure that has doubled in the past 50 years.</p> <p>Founded in 2019, Relevium Medical spun out from Galway&#8217;s <a href="https://www.siliconrepublic.com/start-ups/bioinnovate-ireland-galway-digibio-innovator-dundalk-health-innovation-programme" target="_blank" rel="noopener noreferrer">BioInnovate Ireland</a> programme and currently employs nine people. Its co-founder and CEO <a href="https://www.siliconrepublic.com/innovation/chronic-pain-treatment-wins-e1m-sfi-future-innovator-prize" target="_blank" rel="noopener noreferrer">Dr Alison Liddy</a> was recently one of the runners up for the <a href="https://www.siliconrepublic.com/start-ups/peri-menopause-hpsu-2024-heidi-davis" target="_blank" rel="noopener noreferrer">Enterprise Ireland High-Potential Start-Up Founder of the Year Award</a>, which went to Heidi Davis, the co-founder and CEO of Peri.</p> <p>Liddy said the company was &#8220;thrilled&#8221; to develop the project in partnership with University of Galway and HookeBio &ldquo;to advance this innovative solution for knee osteoarthritis&rdquo;.</p> <p>&#8220;This collaboration represents a significant step forward in addressing a condition that impacts millions worldwide and underscores Relevium Medical&rsquo;s commitment to building a robust R&amp;D pipeline.&#8221;</p> <p>Also working on the project are&nbsp;a research team led by Dr Leo Quinlan from Galway&rsquo;s College of Medicine, Nursing and Health Sciences and Prof Olivier Thomas from Galway&rsquo;s College of Science and Engineering. The research team has developed innovative pain model platforms and a drug screen programme, and analysed biomolecules derived from marine organisms that uniquely target the key receptors the team have identified in knee osteoarthritis.</p> <p>Prof Martin O&#8217;Halloran, director of BioInnovate Ireland and co-founder of Relevium Medical, said that BioInnovate is delighted with the success of Relevium. &#8220;We are particularly proud of the fact that Relevium is a female-led company, and we hope Relevium&rsquo;s achievement will encourage other ambitious women to join the BioInnovate programme.&#8221;</p> <p>In 2022, Relevium Medical was <a href="https://www.siliconrepublic.com/start-ups/eic-transition-funding-relevium-medical-helixworks" target="_blank" rel="noopener noreferrer">awarded &euro;2m</a> from the European Innovation Council (EIC) to develop a triple-action injectable treatment for osteoarthritis.</p> <p><strong><em>Don&rsquo;t miss out on the knowledge you need to succeed. 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