UZ Leuven largest centre in Belgium for life-saving PEA treatment

<!DOCTYPE html> <html lang="en" dir="ltr"> <head> <meta charset="utf-8" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <link rel="icon" href="/themes/custom/drupack/favicon.ico" type="image/vnd.microsoft.icon" /> <link rel="alternate" hreflang="en" href="https://www.uzleuven.be/en/news/uz-leuven-largest-centre-belgium-life-saving-pea-treatment" /> <link rel="alternate" hreflang="nl" href="https://www.uzleuven.be/nl/nieuws/uz-leuven-grootste-centrum-belgie-voor-levensreddende-pea-behandeling" /> <link rel="dns-prefetch" href="https://www.googletagmanager.com"> <link rel="dns-prefetch" href="https://wmimages.uzleuven.be"> <link rel="dns-prefetch" href="https://assets.uzleuven.be"> <title>UZ Leuven largest centre in Belgium for life-saving PEA treatment | UZ Leuven</title> <meta name="twitter:card" content="summary" /> <meta property="og:title" content="UZ Leuven largest centre in Belgium for life-saving PEA treatment" /> <meta name="description" content="UZ Leuven saccounts for the largest number of pulmonary endarteriectomies in Belgium, with remarkably good survival rates. The cardio-surgeons and pulmonologists involved nurture an ambitious vision for the future: centralise the procedure even more and aim for at least 33 operations a year. " /> <meta property="og:description" content="UZ Leuven saccounts for the largest number of pulmonary endarteriectomies in Belgium, with remarkably good survival rates. The cardio-surgeons and pulmonologists involved nurture an ambitious vision for the future: centralise the procedure even more and aim for at least 33 operations a year. 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The cardio-surgeons and pulmonologists involved nurture an ambitious vision for the future: centralise the procedure even more and aim for at least 33 operations a year. </div> <div class="toc hero__toc"> <div class="toc__title">Op deze pagina</div> <ul class="toc__list has-columns"> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#life-saving-procedure">Life-saving procedure</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#technical-feat">Technical feat</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#increasing-number-of-procedures">Increasing number of procedures</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#lung-embolism">Lung embolism聽</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#centralising-care">Centralising care</a> </span> </li> <li class="toc__item"> <svg class="toc__icon is-down" width="20" height="20" aria-hidden="true"> <use xlink:href="#arrow-right" /> </svg> <span class="toc__text"> <a class="toc__link" href="#related">Related</a> </span> </li> </ul> </div> </div> <div class="hero__media"> <figure class="media"> <div class="media__content"> <img class="media__img hero__media__img" src="https://wmimages.uzleuven.be/styles/57eef194148f5468c7316818506af58a703ab731/2024-07/hart_longen_finaal.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6Imluc2lkZSIsIndpZHRoIjoxMzIwLCJoZWlnaHQiOjgwMCwid2l0aG91dEVubGFyZ2VtZW50Ijp0cnVlfX1d&sign=11ee3c4ac2975623beda0f21d7a1b8cf9cbe6e23451b954a20f0b446d1dd387d" alt="" /> </div> </figure> </div> </header> <div class="l-content"> <article class="l-content__cbs "> <div class="cbs "> <div id="f823d296-d03f-493b-956c-d45ad3d9fc8d" class="block--text text"> <h2 id="life-saving-procedure">Life-saving procedure</h2><p>Pulmonal endarterectomy, or PEA for short, is a complex but life-saving procedure for cardiac patients with chronic thromboembolic pulmonal hyertension (CTEPH). </p><p>CTEPH results from pulmonary emboli (blood clots in the bloodstream to the lungs) that are not broken down by the body but scarred. The scarred tissue starts to completely or partially clog the pulmonary vessels, forcing the heart to pump much harder to send blood through the blood vessels of the lungs. As a result, blood pressure in the lungs gets abnormally high. If untreated, CTEPH will continue to get worse: if pressure in the pulmonary vessels continues to increase, it can lead to reduced heart pump function and eventually even to heart failure. A successful procedure lowers or normalises pressure in the lungs, which leads to improved fitness and a higher life expectancy of the patient.  </p> </div> <div id="c062bba9-58c6-41b7-888f-0f2f36e5e287" class="block--text text"> <h2 id="technical-feat">Technical feat</h2><p>During the six-hour procedure, the chest is opened via sternotomy, splitting the sternum in half lengthwise. Next, the heart-lung machine temporarily takes over the function of the heart and lungs. The pulmonary artery is surgically opened after which the inner wall, including the scarred blood clots, is carefully removed. To be able to do this, the patient is cooled down to 18° C with the help of the heart-lung machine. This allows not only the heart, but also the heart-lung machine itself, to be stopped for a while and the pulmonary arteries to be completely free of blood. Afterwards, the patient is rewarmed, the patient's heart starts beating again and the heart-lung machine is stopped. </p> </div> <figure class="media is-large js-lightbox" id=""> <div class="media__wrapper"> <div class="media__controls"> <button class="fullscreen-btn js-lightbox-btn"> <svg class="flickity-button-icon is-expand" viewBox="0 0 32 32" aria-label="View full-screen" title="View full-screen"><path d="M15,20,7,28h5v4H0V20H4v5l8-8Zm5-5,8-8v5h4V0H20V4h5l-8,8Z"></path></svg> <svg class="flickity-button-icon is-inline" viewBox="0 0 32 32" aria-label="Exit full-screen" title="Exit full-screen"><path d="M32,3l-7,7h5v4H18V2h4V7l7-7ZM3,32l7-7v5h4V18H2v4H7L0,29Z"></path></svg> </button> </div> <div class="media__content"> <img class="media__img" src="https://wmimages.uzleuven.be/styles/d2d7f772fa09ca4f0d22d6aff2bf5763163bfa97/2024-07/pulmonale_endarteriectomie.png?style=W3sicmVzaXplIjp7ImZpdCI6Imluc2lkZSIsIndpZHRoIjoxNDIwLCJoZWlnaHQiOjEwODAsIndpdGhvdXRFbmxhcmdlbWVudCI6dHJ1ZX19XQ==&sign=5498ed2254db8b79928ef1269f2db389e791cff5160fde2a5e4b652676eda850" alt="" /> <figcaption class="media__caption"> <span class="media__caption__text"><p>漏 Guth S, et al. Ann Cardiothorac Surg 2022:1 1:180-188.</p></span> </figcaption> </div> </div> </figure> <div id="387f1e62-e5c1-4c46-aa0c-29be8bf612fa" class="block--text text"> <h2 id="increasing-number-of-procedures">Increasing number of procedures</h2><p>On 14 June 2024 the surgical team performed its three hundredth PEA surgery at UZ Leuven since its inception in 1999. In those 25 years the annual number of PEA procedures has been increasing steadily: from nine in the first ten years to twelve in the following decade. The last five years there were some 17 procedures a year. 2023 was a record year with 25 procedures.  </p><p>The programme was initially set up by prof. dr. Marion Delcroix and the first procedures were performed by prof. dr. Willem Daenen. In 2006, cardiac surgeon prof. dr. Bart took over the programme and since 2018, prof. dr. Tom Verbelen performed the last 110 procedures. </p> </div> <blockquote class="quote" id="by-talking-to-the-referring-doctors-i-hope-to-increase-knowledge-and-raise-awareness-about-cteph-and-to-increase-the-number-of-pea-procedures"> <div class="quote__content "> <svg class="quote__quotemark" width="50" height="36" xmlns="http://www.w3.org/2000/svg"><path d="M10.976 13.09c6.034 0 10.926 5.13 10.926 11.455C21.902 30.872 17.01 36 10.976 36 4.94 36 .049 30.872.049 24.545L0 22.91C0 10.257 9.784 0 21.854 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.413 16.413 0 0 0-1.553 1.893c.558-.092 1.13-.14 1.713-.14zm28.097 0C45.108 13.09 50 18.22 50 24.546 50 30.872 45.108 36 39.073 36c-6.034 0-10.927-5.128-10.927-11.455l-.048-1.636C28.098 10.257 37.882 0 49.95 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.404 16.404 0 0 0-1.552 1.893c.558-.092 1.13-.14 1.712-.14z" fill="#007ACC" fill-rule="nonzero"/></svg> <div class="quote__text"> By talking to the referring doctors, I hope to increase knowledge and raise awareness about CTEPH and to increase the number of PEA procedures. </div> <img class="quote__img quote__img--no-crop" src="https://wmimages.uzleuven.be/styles/034258334255ab987a62b481374b11de7e3f51d4/2024-07/tom_verbelen.jfif?style=W3sicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjI0MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOnRydWV9fV0=&sign=5174c35f9fb28f5299110a971deeb8904950858fc3df0df0c13ca229162d2fa2" /> <div class="quote__source">Prof. dr. Tom Verbelen</div> </div> </blockquote> <div id="05ee65b6-a519-42a7-9c12-28c736adf29a" class="block--text text"> <p><strong>Prof. dr. Tom Verbelen</strong>, cardiac surgeon and cardiac surgery deputy head of clinic: “Together with better centralisation of care, it remains UZ Leuven's ambition to achieve the target of 33 procedures per year in the future. According to current guidelines, an expertise centre needs to perform at least 50 PEA treatment a year and have a mortality rate of less than 5 percent. But recently we have determined a 'volume outcome' based on scientific literature. This showed that an expertise centre should at least perform 33 PEA treatment a year, rather than 50. By talking with referring doctors, I'm hoping to increase knowledge and raise awareness about CTEPH and to increase the number of PEA procedures. And even though we are currently still performing less than 33 procedures a year, I am proud that our mortality rate in planned procedures is lower than 4% putting us on a par with the largest centres worldwide. </p> </div> <div id="01a16e2e-8d22-4a6b-a6bb-d792339daaa7" class="block--text text"> <h2 id="lung-embolism">Lung embolism </h2><p>In pulmonary embolism, a blood vessel in the lungs becomes blocked by one or more blood clots. These can originate from the blood vessels in the limbs or the abdomen after a thrombosis and then be carried along with the blood flow that reaches the lungs via the heart. Usually a pulmonary embolism can be easily treated with anticoagulants, but one or more blood clots may also fail to dissolve properly. This, in turn, can lead to CTEPH. </p><p>Every year, 1 in 1,000 Belgians suffer a pulmonary embolism. Approximately 3 percent of the patients develops CTEPH. So every year, there are about 199 new patients with CTEPH in Belgium. </p> </div> <div id="f7666295-940f-4093-ac56-176598eafd57" class="block--text text"> <p><strong>Prof. dr. Verbelen</strong>: “A pulmonal endarterectomy is one of the procedures I prefer to perform. On the one hand because of the surgical technical challenge and because of the of the often immediately noticeable result in the patient. On the other hand, because it is a nice example of a multidisciplinary care programme: pulmonologists, cardiologists, radiologists, interventional radiologists, cardiac surgeons, anaesthesiologists, intensivists but also nurses, perfusionists, nursing specialists and physiotherapists are all involved. I sincerely hope that the efforts from the team can result in a further increase in the number of procedures in the future.”</p> </div> <div class="cta bg-light-blue"> <div class="cta__content cta--align-image-right"> <div class="cta__wrapper"> <h2 class="cta__title heading-3" id="centralising-care"> Centralising care </h2> <div class="cta__description text is-reset"> <p>Centralising care mean concentrating medical care and treatments for certain conditions or patient groups in a specific location or at a specialised medical centre. The objective of centralisation is improving quality of care by pooling expertise and means in one location.</p> </div> </div> </div> </div> <h2 class="heading-2" id="related">Related</h2> <div class="message is-accent is-link" href="/en/news/podcast-wouter-oosterlinck-robotics-cardiac-surgery"> <div class="message__content"> <div class="message__meta meta">More about "Cardiac surgery"</div> <h3 class="message__title heading-3">Podcast: Wouter Oosterlinck on Robotics in Cardiac Surgery</h3> <div class="messsage__date meta">20 November 2024</div> <div class="message__text">Prof. Dr. Wouter Oosterlinck discusses the advancements in robotics for cardiac surgery, his experiences in developing an innovative minimally invasive program at UZ Leuven, and its impact on this rapidly evolving field.</div> <a class="link-btn" href="/en/news/podcast-wouter-oosterlinck-robotics-cardiac-surgery" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div class="message is-accent is-link" href="/en/news/professor-paul-herijgers-become-new-ceo-uz-leuven"> <div class="message__content"> <div class="message__meta meta">More about "Cardiac surgery"</div> <h3 class="message__title heading-3">Professor Paul Herijgers to become new CEO of UZ Leuven</h3> <div class="messsage__date meta">30 April 2024</div> <div class="message__text">On 1 August 2024 prof. dr. Paul Herijgers will become the new CEO of UZ Leuven. He will take over the baton from prof. dr. Wim Robberecht, who will end his tenure and retire on 31 July 2024. </div> <a class="link-btn" href="/en/news/professor-paul-herijgers-become-new-ceo-uz-leuven" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div class="message is-accent is-link" href="/en/news/uz-leuven-team-supports-cardiac-surgery-nicaragua-week"> <div class="message__content"> <div class="message__meta meta">More about "Cardiac surgery"</div> <h3 class="message__title heading-3">UZ Leuven team supports cardiac surgery in Nicaragua for a week</h3> <div class="messsage__date meta">17 April 2023</div> <div class="message__text">At the end of January 2023 ten UZ Leuven employees went on a mission to Nicaragua, under the supervision of World Heart Caregivers. Together with the local nurses, they rolled up their sleeves for a week at the operating theatre in the capital Managua. </div> <a class="link-btn" href="/en/news/uz-leuven-team-supports-cardiac-surgery-nicaragua-week" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div id="feedback" data-i18n="{"formSource":"node:1caad80f-0fd0-4d9d-8b90-1c23347e4635","done":"Thanks for your feedback.","title":"Remarks about this page?","button_yes":"Let us know","email_label":"Email","feedback_label":"Feedback","submit_label":"Submit feedback","error_messages":{"required":"This field is required.","email":"Invalid email.","min_char":"At least 20 characters are required."},"description":"For personal medical enquiries, you have to make an appointment with a physician."}"></div> <div class="meta"> Last edit: 3 October 2024 </div> </div> </article> </div> </main> <footer> <div class="footer"> <div class="footer__row"> <div class="footer__inside"> <div class="footer__columns"> <div class="footer__column"> <h4 class="footer__heading heading-3">Contact</h4> <p><a href="tel:+3216332211" target="_blank" rel="noreferrer noopener">+32 16 33 22 11</a></p> <p>Herestraat 49, 3000 Leuven, Belgium</p> <p><a href="/en/node/13495">All contact information</a></p> <div class="social-list"> <span class="social-list__title">Also find us on:</span> <ul class="list horizontal-list is-small"> <li> <a class="footer__social icon--facebook" href="https://www.facebook.com/uzleuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#facebook"></use></svg> <span class="visually-hidden">Facebook</span> </a> </li> <li> <a class="footer__social icon--twitter" href="https://twitter.com/uzleuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#twitter"></use></svg> <span class="visually-hidden">Twitter</span> </a> </li> <li> <a class="footer__social icon--linkedin" href="https://www.linkedin.com/company/uz-leuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#linkedin"></use></svg> <span class="visually-hidden">LinkedIn</span> </a> </li> </ul> </div> </div> <div class="footer__column"> <h4 class="footer__heading heading-3"> <a class="heading-link" href="/en/consultation-and-admission"><span class="heading-link__text">Consultation and admission</span></a> </h4> <ul class="list"> <li> <a href="/en/consultation-and-admission/consultation-and-function-tests">Consultation</a> </li> <li> <a href="/en/consultation-and-admission/admission">Admission</a> </li> <li> <a href="/en/visits">Visiting hours</a> </li> <li> <a href="/en/greeting-card">Send a greeting card</a> </li> </ul> </div> <div class="footer__column"> <h4 class="footer__heading heading-3"> <a class="heading-link" href="/en/about-us"><span class="heading-link__text">About UZ Leuven</span></a> </h4> <ul class="list"> <li> <a href="/en/news-and-calendar">News and publications</a> </li> <li> <a href="/en/press-and-media">For press and media</a> </li> </ul> </div> </div> </div> </div> <div class="footer__row"> <div class="footer__inside"> <div class="footer__logos footer__columns"></div> </div> </div> </div> <div class="closure"> <div class="closure__inside"> <div class="closure__content"> <ul class="list horizontal-list is-nav closure__links" id="closure"> <li class="closure__item"><a class="closure__link" href="/en/cookie-policy">Cookie policy</a></li> <li class="closure__item"><a class="closure__link" href="/en/privacy-and-your-patient-record">Privacy</a></li> </ul> </div> <div class="closure__wieni"> <a class="wieni" href="https://www.wieni.be" target="_blank" title="site by wieni" rel="noopener noreferrer"> <svg class="wieni__logo" width="61" height="22"><use xlink:href="#wieni"></use></svg> </a> </div> </div> </div> </footer> </div> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"en\/","currentPath":"node\/21545","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"wmcustom_urls":{"search":"\/en\/search"},"analytics":{"nodeType":"Nieuws","isMedischeDienst":0},"outdatedBrowser":{"title":"Your browser is out-of-date","message":"\u003Cp\u003EIt seems you\u0027re using an outdated version of browser-name. 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