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[o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>دخول</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> صفحات للمحررين الذين سجَّلوا خروجهم <a href="/wiki/%D9%85%D8%B3%D8%A7%D8%B9%D8%AF%D8%A9:%D9%85%D9%82%D8%AF%D9%85%D8%A9" aria-label="تعلَّم المزيد بخصوص التحرير"><span>تعلَّم المزيد</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D9%85%D8%B3%D8%A7%D9%87%D9%85%D8%A7%D8%AA%D9%8A" title="قائمة بتعديلات قام بها عنوان الآي بي [y]" accesskey="y"><span>مساهمات</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D9%86%D9%82%D8%A7%D8%B4%D9%8A" title="نقاش حول التعديلات من عنوان الأيبي هذا [n]" accesskey="n"><span>نقاش</span></a></li> </ul> </div> </div> </div> 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data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">المحتويات</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">انقل للشريط الجانبي</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">أخف</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">المقدمة</div> </a> </li> <li id="toc-الوظيفة" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#الوظيفة"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>الوظيفة</span> </div> </a> <ul id="toc-الوظيفة-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-الأهمية_السريرية" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#الأهمية_السريرية"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>الأهمية السريرية</span> </div> </a> <ul id="toc-الأهمية_السريرية-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-المراجع" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#المراجع"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>المراجع</span> </div> </a> <ul id="toc-المراجع-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-قراءة_متعمقة" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#قراءة_متعمقة"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>قراءة متعمقة</span> </div> </a> <ul id="toc-قراءة_متعمقة-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="المحتويات" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="تبديل عرض جدول المحتويات" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">تبديل عرض جدول المحتويات</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">ABCB4</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="اذهب إلى المقالة في لغةٍ أخرى. مُتاحة في 4 لغات" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-4" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">4 لغات</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-arz mw-list-item"><a href="https://arz.wikipedia.org/wiki/ABCB4" title="ABCB4 – Egyptian Arabic" lang="arz" hreflang="arz" data-title="ABCB4" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target"><span>مصرى</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/ABCB4" title="ABCB4 – الإنجليزية" lang="en" hreflang="en" data-title="ABCB4" data-language-autonym="English" data-language-local-name="الإنجليزية" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/ABCB4" title="ABCB4 – البولندية" lang="pl" hreflang="pl" data-title="ABCB4" data-language-autonym="Polski" data-language-local-name="البولندية" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/ABCB4" title="ABCB4 – الأوكرانية" lang="uk" hreflang="uk" data-title="ABCB4" data-language-autonym="Українська" data-language-local-name="الأوكرانية" class="interlanguage-link-target"><span>Українська</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q15315974#sitelinks-wikipedia" title="تعديل وصلات اللغات" class="wbc-editpage">عدل الوصلات</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="نطاقات"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/ABCB4" title="اعرض صفحة المحتوى [c]" accesskey="c"><span>مقالة</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/%D9%86%D9%82%D8%A7%D8%B4:ABCB4" rel="discussion" title="نقاش صفحة المحتوى [t]" accesskey="t"><span>نقاش</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="غيّر لهجة اللغة" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">العربية</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="معاينة"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/ABCB4"><span>اقرأ</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=ABCB4&action=edit" title="عدل الكود المصدري لهذه الصفحة [e]" accesskey="e"><span>عدّل</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=ABCB4&action=history" title="النسخ السابقة لهذه الصفحة [h]" accesskey="h"><span>تاريخ</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="أدوات الصفحة"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="أدوات" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">أدوات</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">أدوات</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">انقل للشريط الجانبي</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">أخف</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="المزيد من الخيارات" > <div class="vector-menu-heading"> إجراءات </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/ABCB4"><span>اقرأ</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=ABCB4&action=edit" title="عدل الكود المصدري لهذه الصفحة [e]" accesskey="e"><span>عدّل</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=ABCB4&action=history"><span>تاريخ</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> عام </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D9%85%D8%A7%D8%B0%D8%A7_%D9%8A%D8%B5%D9%84_%D9%87%D9%86%D8%A7/ABCB4" title="قائمة بكل صفحات الويكي التي تصل هنا [j]" accesskey="j"><span>ماذا يصل هنا</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D8%A3%D8%AD%D8%AF%D8%AB_%D8%A7%D9%84%D8%AA%D8%BA%D9%8A%D9%8A%D8%B1%D8%A7%D8%AA_%D8%A7%D9%84%D9%85%D9%88%D8%B5%D9%88%D9%84%D8%A9/ABCB4" rel="nofollow" title="أحدث التغييرات في الصفحات الموصولة من هذه الصفحة [k]" accesskey="k"><span>تغييرات ذات علاقة</span></a></li><li id="t-upload" class="mw-list-item"><a href="/wiki/ويكيبيديا:رفع" title="ارفع ملفات [u]" accesskey="u"><span>رفع ملف</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/%D8%AE%D8%A7%D8%B5:%D8%B5%D9%81%D8%AD%D8%A7%D8%AA_%D8%AE%D8%A7%D8%B5%D8%A9" title="قائمة بكل الصفحات الخاصة [q]" accesskey="q"><span>الصفحات الخاصة</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=ABCB4&oldid=60739278" title="وصلة دائمة لهذه النسخة من الصفحة"><span>وصلة دائمة</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=ABCB4&action=info" title="المزيد من المعلومات عن هذه الصفحة"><span>معلومات الصفحة</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:%D8%A7%D8%B3%D8%AA%D8%B4%D9%87%D8%A7%D8%AF&page=ABCB4&id=60739278&wpFormIdentifier=titleform" title="معلومات عن كيفية الاستشهاد بالصفحة"><span>استشهد بهذه الصفحة</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:%D8%AA%D9%82%D8%B5%D9%8A%D8%B1_%D8%A7%D9%84%D9%85%D8%B3%D8%A7%D8%B1&url=https%3A%2F%2Far.wikipedia.org%2Fwiki%2FABCB4"><span>احصل على مسار مختصر</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:QrKodu&url=https%3A%2F%2Far.wikipedia.org%2Fwiki%2FABCB4"><span>تنزيل رمز الاستجابة السريعة</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> طباعة/تصدير </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:%D9%83%D8%AA%D8%A7%D8%A8&bookcmd=book_creator&referer=ABCB4"><span>إنشاء كتاب</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=%D8%AE%D8%A7%D8%B5:DownloadAsPdf&page=ABCB4&action=show-download-screen"><span>تحميل PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=ABCB4&printable=yes" title="نسخة للطباعة لهذه الصفحة [p]" accesskey="p"><span>نسخة للطباعة</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> في مشاريع أخرى </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q15315974" title="وصلة إلى المادة المرتبطة في مستودع البيانات المركزي [g]" accesskey="g"><span>عنصر ويكي بيانات</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="أدوات الصفحة"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="المظهر"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">المظهر</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">انقل للشريط الجانبي</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">أخف</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">من ويكيبيديا، الموسوعة الحرة</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-rtl mw-parser-output" lang="ar" dir="rtl"><table class="infobox" style="width:26.4em"> <tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">ABCB4 </th></tr><tr><td colspan="4" style="text-align:center"></td> </tr><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2">معرفات </th></tr><tr><th scope="row" style="background-color:#fbf8cc"><span class="plainlinks"><a class="external text" href="https://ar.wikipedia.org/wiki/منظمة_جينوم_الإنسان">أسماء بديلة</a></span> </th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=45">ABCB4</a>, </span> ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3, ATP binding cassette subfamily B member 4</td> </tr><tr><th scope="row" style="background-color:#fbf8cc">معرفات خارجية</th> <td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/%D8%A7%D9%84%D9%88%D8%B1%D8%A7%D8%AB%D8%A9_%D8%A7%D9%84%D9%85%D9%86%D8%AF%D9%84%D9%8A%D8%A9_%D8%A7%D9%84%D8%A8%D8%B4%D8%B1%D9%8A%D8%A9_%D8%B9%D8%A8%D8%B1_%D8%A7%D9%84%D8%A5%D9%86%D8%AA%D8%B1%D9%86%D8%AA" title="الوراثة المندلية البشرية عبر الإنترنت">الوراثة المندلية البشرية عبر الإنترنت</a> <a rel="nofollow" class="external text" href="https://omim.org/entry/171060">171060</a> <a href="/wiki/Mouse_Genome_Informatics" class="mw-redirect" title="Mouse Genome Informatics">MGI:</a> <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:MGI:97569">MGI:97569</a> <a href="/wiki/HomoloGene" class="mw-redirect" title="HomoloGene">HomoloGene:</a> <a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=136368">136368</a> <a href="/wiki/GeneCards" class="mw-redirect" title="GeneCards">GeneCards:</a> <a rel="nofollow" class="external text" href="http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=5244">5244</a> </span> </td></tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/%D8%B1%D9%82%D9%85_%D8%A7%D9%84%D8%AA%D8%B5%D9%86%D9%8A%D9%81_%D8%A7%D9%84%D8%A5%D9%86%D8%B2%D9%8A%D9%85%D9%8A" title="رقم التصنيف الإنزيمي">رقم التصنيف الإنزيمي</a></th> <td colspan="3" style="background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.genome.jp/dbget-bin/www_bget?enzyme+7.6.2.2">7.6.2.2</a></span> </td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"> <table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:right"> <tbody><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2"><a href="/wiki/%D8%B9%D9%84%D9%85_%D8%A7%D9%84%D9%88%D8%AC%D9%88%D8%AF_%D8%A7%D9%84%D8%AC%D9%8A%D9%86%D9%8A" title="علم الوجود الجيني">علم الوجود الجيني</a></th> </tr><tr><th style="background-color:#fbf8cc">وظائف جزيئية</th><td style="background-color:#eee"> <p><span class="plainlinks"><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042626">ATPase-coupled transmembrane transporter activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0000166">nucleotide binding</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008559">ABC-type xenobiotic transporter activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008525">phosphatidylcholine transporter activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0090554">phosphatidylcholine floppase activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016887">ATPase activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515،">‏GO:0001948، ‏GO:0016582 ربط بروتيني</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016787">نشاط هيدرولاز</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005524">ATP binding</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005548">phospholipid transporter activity</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0099038">ceramide floppase activity</a><br /></span> </p> </td></tr><tr><th style="background-color:#fbf8cc">مكونات خلوية</th><td style="background-color:#eee"> <p><span class="plainlinks"><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005737">سيتوبلازم</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016021">مكون تكاملي للغشاء</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016020">غشاء</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005886">غشاء خلوي</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005887">integral component of plasma membrane</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046581">intercellular canaliculus</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016324">apical plasma membrane</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045121">طوافات دهنية</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070062">حويصلة خارج خلوية</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031410،">‏GO:0016023 حويصلة سيتوبلازمية</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030136">clathrin-coated vesicle</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005654">بلازم نووي</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005829">عصارة خلوية</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005925">التصاقات بؤرية</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0015629">actin cytoskeleton</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031526">brush border membrane</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045177">apical part of cell</a><br /></span> </p> </td></tr><tr><th style="background-color:#fbf8cc">عمليات حيوية</th><td style="background-color:#eee"> <p><span class="plainlinks"><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006869">lipid transport</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1903413">cellular response to bile acid</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0032376">positive regulation of cholesterol transport</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0061092">positive regulation of phospholipid translocation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006855">xenobiotic transmembrane transport</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006629">أيض الليبيدات</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:2001140">positive regulation of phospholipid transport</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1901557">response to fenofibrate</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042908">xenobiotic transport</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0055085">نقل عبر الغشاء</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0055088">lipid homeostasis</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0032782">bile acid secretion</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0045332">phospholipid translocation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001666">response to hypoxia</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001890">تكون المشيمة</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007420">brain development</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007595">رضاعة</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007623">نظم يوماوي</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0009914">hormone transport</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010033">response to organic substance</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010046">response to mycotoxin</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0014070،">‏GO:1904578 response to organic cyclic compound</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0014072">response to isoquinoline alkaloid</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031667">response to nutrient levels</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0032355">response to estradiol</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0033189">response to vitamin A</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0033231">carbohydrate export</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0033280">response to vitamin D</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0035633">maintenance of blood-brain barrier</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0036146">cellular response to mycotoxin</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043215">daunorubicin transport</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043278">response to morphine</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046618">xenobiotic export</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046686">response to cadmium ion</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050892">امتصاص معوي</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0060548">negative regulation of cell death</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0060856">establishment of blood-brain barrier</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071217">cellular response to external biotic stimulus</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071236،">‏GO:1904577 cellular response to antibiotic</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071312">cellular response to alkaloid</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071392">cellular response to estradiol stimulus</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071407،">‏GO:1904579 cellular response to organic cyclic compound</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071475">cellular hyperosmotic salinity response</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071548">response to dexamethasone</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0071549">cellular response to dexamethasone stimulus</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0097068">response to thyroxine</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0097327">response to antineoplastic agent</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0099040">ceramide translocation</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1902065">response to L-glutamate</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1903416">response to glycoside</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1905231">cellular response to borneol</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1905232">cellular response to L-glutamate</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1905233">response to codeine</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1905235">response to quercetin</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1905237">response to cyclosporin A</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1990962">xenobiotic transport across blood-brain barrier</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1990963">establishment of blood-retinal barrier</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:2001025">positive regulation of response to drug</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0019216">regulation of lipid metabolic process</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:1904478">regulation of intestinal absorption</a><br /><strong>•</strong> <a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006810،">‏GO:0015915 نقل</a><br /></span> </p> </td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">المصادر:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2">نمط التعبير عن الحمض النووي الريبوزي</th> </tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/%D9%85%D9%84%D9%81:PBB_GE_ABCB4_207819_s_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/PBB_GE_ABCB4_207819_s_at_fs.png/220px-PBB_GE_ABCB4_207819_s_at_fs.png" decoding="async" width="220" height="159" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/83/PBB_GE_ABCB4_207819_s_at_fs.png/330px-PBB_GE_ABCB4_207819_s_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/83/PBB_GE_ABCB4_207819_s_at_fs.png/440px-PBB_GE_ABCB4_207819_s_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td> </tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/5244/">المزيد من بيانات التعبير المرجعية</a></span> </td></tr><tr><th colspan="4" style="text-align:center;background-color:#ffcfd2">تماثلات متسلسلة</th> </tr><tr><th scope="row" style="background-color:#fbf8cc">أنواع</th> <td><b>الإنسان</b></td> <td><b>الفأر</b></td> </tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/%D8%A3%D9%86%D8%AA%D8%B1%D9%8A%D9%87" title="أنتريه">أنتريه</a></th> <td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=5244&rn=1">5244</a></span> </td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=18670&rn=1">18670</a></span> </td></tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th> <td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000005471;db=core">ENSG00000005471</a></span> </td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000042476;db=core">ENSMUSG00000042476</a></span> </td></tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/%D9%8A%D9%88%D9%86%D9%8A%D8%A8%D8%B1%D9%88%D8%AA" title="يونيبروت">يونيبروت</a></th> <td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1"><span class="plainlinks"></span></th> </tr><tr><td colspan="1"> <p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P21439">P21439</a><br /><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/E7EQI1">E7EQI1</a> </p></td></tr></tbody></table> </td><td><table style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1"><span class="plainlinks"></span></th> </tr><tr><td colspan="1"> <p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.uniprot.org/uniprot/P21440">P21440</a> </p></td></tr></tbody></table> </td></tr><tr><th scope="row" style="background-color:#fbf8cc">RefSeq (<a href="/wiki/%D9%85%D8%B1%D8%B3%D8%A7%D9%84_%D8%A7%D9%84%D8%AD%D9%85%D8%B6_%D8%A7%D9%84%D9%86%D9%88%D9%88%D9%8A_%D8%A7%D9%84%D8%B1%D9%8A%D8%A8%D9%88%D8%B2%D9%8A" class="mw-redirect" title="مرسال الحمض النووي الريبوزي">رنا مرسال.</a>)</th> <td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th> </tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_000443،">‏NM_018849، ‏NM_018850، ‏XM_011516308، ‏XM_011516309، ‏XM_011516310، ‏XM_011516311، ‏XM_011516312، ‏XM_011516313، ‏XM_011516315، ‏XM_017012323، ‏XR_001744809، ‏XR_001744810 NM_000443، ‏NM_018849، ‏NM_018850، ‏XM_011516308، ‏XM_011516309، ‏XM_011516310، ‏XM_011516311، ‏XM_011516312، ‏XM_011516313، ‏XM_011516315، ‏XM_017012323، ‏XR_001744809، ‏XR_001744810</a></span> </p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th> </tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_008830،">‏XM_006503551، ‏XM_006503552، ‏XM_006503554، ‏XM_036164874 NM_008830، ‏XM_006503551، ‏XM_006503552، ‏XM_006503554، ‏XM_036164874</a></span> </p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#fbf8cc"><a href="/wiki/RefSeq" class="mw-redirect" title="RefSeq">RefSeq</a> (بروتين)</th> <td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th> </tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_000434،">‏NP_061337، ‏NP_061338، ‏XP_011514610، ‏XP_011514611، ‏XP_011514612، ‏XP_011514613، ‏XP_011514614، ‏XP_011514615، ‏XP_011514617، ‏XP_016867812 NP_000434، ‏NP_061337، ‏NP_061338، ‏XP_011514610، ‏XP_011514611، ‏XP_011514612، ‏XP_011514613، ‏XP_011514614، ‏XP_011514615، ‏XP_011514617، ‏XP_016867812</a></span> </p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr> <th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"> <p><span class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_032856،">‏XP_006503614، ‏XP_006503615، ‏XP_006503617، ‏XP_036020767 NP_032856، ‏XP_006503614، ‏XP_006503615، ‏XP_006503617، ‏XP_036020767</a></span> </p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#fbf8cc">الموقع (<a href="/wiki/%D9%82%D8%A7%D8%B9%D8%AF%D8%A9_%D8%A8%D9%8A%D8%A7%D9%86%D8%A7%D8%AA_%D8%AC%D8%A7%D9%85%D8%B9%D8%A9_%D9%83%D8%A7%D9%84%D9%8A%D9%81%D9%88%D8%B1%D9%86%D9%8A%D8%A7_(%D8%B3%D8%A7%D9%86%D8%AA%D8%A7_%D9%83%D8%B1%D9%88%D8%B2)" class="mw-redirect" title="قاعدة بيانات جامعة كاليفورنيا (سانتا كروز)">UCSC</a></th> <td><span class="plainlinks">n/a</span> </td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="http://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=mm0&position=chr5:8943717-9009231">Chr 5: 8.94 – 9.01 Mb</a></span> </td></tr><tr><th scope="row" style="background-color:#fbf8cc">بحث <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF" title="ببمد">ببمد</a></th> <td><span class="plainlinks"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=5244">[1]</a></span> </td><td><span class="plainlinks"><a rel="nofollow" class="external autonumber" href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=18670">[2]</a></span> </td></tr><tr><td colspan="4" style="text-align:center;font-size:x-small;background-color:#eee"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A_%D8%A8%D9%8A%D8%A7%D9%86%D8%A7%D8%AA" title="ويكي بيانات">ويكي بيانات</a></td></tr><tr><td colspan="4" style="text-align:center;font-size:x-small;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center;font-size:x-small"><a href="https://www.wikidata.org/wiki/Q15315974" class="extiw" title="d:Q15315974">اعرض/عدّل إنسان</a></td><td colspan="2" style="background-color:#eee;text-align:center;font-size:x-small"><a href="https://www.wikidata.org/wiki/Q15315978" class="extiw" title="d:Q15315978">اعرض/عدّل فأر</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>ABCB4</b>‏ (<b>ATP binding cassette subfamily B member 4</b>) هوَ <a href="/wiki/%D8%A8%D8%B1%D9%88%D8%AA%D9%8A%D9%86" title="بروتين">بروتين</a> <a href="/wiki/%D9%85%D9%86%D8%B7%D9%82%D8%A9_%D9%85%D8%B4%D9%81%D8%B1%D8%A9" title="منطقة مشفرة">يُشَفر</a> بواسطة <a href="/wiki/%D8%AC%D9%8A%D9%86" title="جين">جين</a> ABCB4 في <a href="/wiki/%D8%A5%D9%86%D8%B3%D8%A7%D9%86" title="إنسان">الإنسان</a>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="الوظيفة"><span id=".D8.A7.D9.84.D9.88.D8.B8.D9.8A.D9.81.D8.A9"></span>الوظيفة</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=ABCB4&action=edit&section=1" title="عدل القسم: الوظيفة"><span>عدل</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r68107301">.mw-parser-output .ambox{margin:0;border:1px solid #a2a9b1;border-right:2px solid #36c;background-color:var(--background-color-neutral-subtle,#f8f9fa);box-sizing:border-box}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output .ambox+link+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+style+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+link+.ambox{margin-top:-1px}html body.mediawiki .mw-parser-output .ambox.mbox-small-right{margin:4px 1em 4px 0;overflow:hidden;width:238px;border-collapse:collapse;font-size:88%;line-height:1.25em}.mw-parser-output .ambox-speedy{border:1px solid #b32424;border-right:2px solid #b32424;background-color:var(--background-color-neutral-subtle,#fee7e6)}.mw-parser-output .ambox-delete{border:1px solid #b32424;border-right:2px solid #b32424}.mw-parser-output .ambox-content{border:1px solid #f28500;border-right:2px solid #f28500}.mw-parser-output .ambox-style{border:1px solid #fc3;border-right:2px solid #fc3}.mw-parser-output .ambox-move{border:1px solid #9932cc;border-right:2px solid #9932cc}.mw-parser-output .ambox-current{border:1px solid #A5D6A7;border-right:2px solid #A5D6A7}.mw-parser-output .ambox-featured{border:1px solid #C0C0C0}.mw-parser-output .ambox-protection{border-right:1px solid #a2a9b1;border-right:2px solid #a2a9b1}.mw-parser-output .ambox .mbox-text{border:none;padding:0.25em 0.5em;width:100%;font-size:95%}.mw-parser-output .ambox .mbox-text .date-container{font-size:smaller}.mw-parser-output .ambox .mbox-image{border:none;padding:2px 0.9em 2px 0;text-align:center}.mw-parser-output .ambox .mbox-imageleft{border:none;padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .ambox .mbox-empty-cell{border:none;padding:0;width:1px}.mw-parser-output .ambox .mbox-image-div{width:42px}html.client-js body.skin-minerva .mw-parser-output .mbox-text-span{margin-right:23px!important}@media(min-width:720px){.mw-parser-output .ambox{margin:0}}.mw-parser-output .ambox th.mbox-text,.mw-parser-output .ambox td.mbox-text{padding:0.25em 0.5em;font-size:95%}.mw-parser-output .ambox th.mbox-text .date-container,.mw-parser-output .ambox td.mbox-text .date-container{font-size:small}.mw-parser-output .ambox td.mbox-image{padding:2px 0.2em 2px 0}.mw-parser-output .ambox td.mbox-imageleft{padding:2px 0.2em 2px 0}.mw-parser-output .ambox-notice{border:1px solid #36c;border-right:2px solid #36c}.mw-parser-output .compact-ambox table .mbox-image,.mw-parser-output .compact-ambox table .mbox-imageleft,.mw-parser-output .compact-ambox table .mbox-empty-cell{display:none}.mw-parser-output .compact-ambox table.ambox{border:none;border-collapse:collapse;background-color:transparent;margin:0 1.6em 0 0!important;padding:0!important;width:auto;display:block}body.mediawiki .mw-parser-output .compact-ambox table.mbox-small-right{font-size:100%;width:auto;margin:0}.mw-parser-output .compact-ambox table .mbox-text{padding:0!important;margin:0!important}.mw-parser-output .compact-ambox table .mbox-text-span{display:list-item;line-height:1.5em;list-style-type:square}.mw-parser-output .compact-ambox .hide-when-compact{display:none}.mw-parser-output .compact-ambox .hide-when-compact{display:none}</style><table class="box-قسم_فارغ plainlinks metadata ambox mbox-small-right ambox-content" role="presentation" style="width:auto;"><tbody><tr><td class="mbox-image"><span typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:Crystal_xedit.svg" class="mw-file-description"><img alt="[أيقونة]" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/20px-Crystal_xedit.svg.png" decoding="async" width="20" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/30px-Crystal_xedit.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/40px-Crystal_xedit.svg.png 2x" data-file-width="800" data-file-height="600" /></a></span></td><td class="mbox-text" style="width:auto;"><div class="mbox-text-span"><b>هذا القسم فارغ أو غير مكتمل.</b> ساهم <a class="external text" href="https://ar.wikipedia.org/w/index.php?title=ABCB4&action=edit&section=">في توسيعه</a>. <span class="date-container"><i>(<span class="date">يوليو 2018</span>)</i></span></div></td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="الأهمية_السريرية"><span id=".D8.A7.D9.84.D8.A3.D9.87.D9.85.D9.8A.D8.A9_.D8.A7.D9.84.D8.B3.D8.B1.D9.8A.D8.B1.D9.8A.D8.A9"></span>الأهمية السريرية</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=ABCB4&action=edit&section=2" title="عدل القسم: الأهمية السريرية"><span>عدل</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r68107301"><table class="box-قسم_فارغ plainlinks metadata ambox mbox-small-right ambox-content" role="presentation" style="width:auto;"><tbody><tr><td class="mbox-image"><span typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:Crystal_xedit.svg" class="mw-file-description"><img alt="[أيقونة]" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/20px-Crystal_xedit.svg.png" decoding="async" width="20" height="15" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/30px-Crystal_xedit.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/40px-Crystal_xedit.svg.png 2x" data-file-width="800" data-file-height="600" /></a></span></td><td class="mbox-text" style="width:auto;"><div class="mbox-text-span"><b>هذا القسم فارغ أو غير مكتمل.</b> ساهم <a class="external text" href="https://ar.wikipedia.org/w/index.php?title=ABCB4&action=edit&section=">في توسيعه</a>. <span class="date-container"><i>(<span class="date">يوليو 2018</span>)</i></span></div></td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="المراجع"><span id=".D8.A7.D9.84.D9.85.D8.B1.D8.A7.D8.AC.D8.B9"></span>المراجع</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=ABCB4&action=edit&section=3" title="عدل القسم: المراجع"><span>عدل</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r64185426">.mw-parser-output .reflist{font-size:90%;margin-bottom:0.5em;list-style-type:decimal;overflow-y:auto;max-height:300px}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}@media print{.mw-parser-output .reflist{overflow-y:visible!important;max-height:none!important}}</style><div class="reflist mw-content-ltr" dir="ltr"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r67739214">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")left 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")left 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")left 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")left 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20100112141221/http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5244">"Entrez Gene: ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4"</a>. مؤرشف من <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5244">الأصل</a> في 2010-01-12.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+ABCB4+ATP-binding+cassette%2C+sub-family+B+%28MDR%2FTAP%29%2C+member+4&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D5244&rfr_id=info%3Asid%2Far.wikipedia.org%3AABCB4" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r67739214"><cite id="CITEREFVan_der_BliekBaasTen_Houte_de_LangeKooiman1988" class="citation journal cs1">Van der Bliek AM، Baas F، Ten Houte de Lange T، Kooiman PM، Van der Velde-Koerts T، Borst P (مارس 1988). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC553787">"The human mdr3 gene encodes a novel P-glycoprotein homologue and gives rise to alternatively spliced mRNAs in liver"</a>. <i>The EMBO Journal</i>. ج. 6 ع. 11: 3325–31. <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF_%D8%B3%D9%86%D8%AA%D8%B1%D8%A7%D9%84" title="ببمد سنترال">PMC</a>:<span class="id-lock-free" title="يمكن الوصول إليها بحرية"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC553787">553787</a></span>. <a href="/wiki/%D8%A8%D8%A8%D9%85%D8%AF" title="ببمد">PMID</a>:<a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2892668">2892668</a>.</cite><span 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class="citation journal cs1">Rosmorduc O، Hermelin B، Poupon R (أبريل 2001). 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href="/w/index.php?title=%D8%AC%D9%8A%D9%86%D8%A7%D8%AA_%D8%A7%D9%84%D9%83%D8%B1%D9%88%D9%85%D9%88%D8%B3%D9%88%D9%85_7&action=edit&redlink=1" class="new" title="جينات الكروموسوم 7 (الصفحة غير موجودة)">جينات الكروموسوم 7</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ARF5" title="ARF5">ARF5</a></li> <li><a href="/wiki/RAPGEF5" title="RAPGEF5">RAPGEF5</a></li> <li><a href="/wiki/AP1S1" title="AP1S1">AP1S1</a></li> <li><a href="/wiki/ASZ1" title="ASZ1">ASZ1</a></li> <li><a href="/wiki/RASA4B" title="RASA4B">RASA4B</a></li> <li><a href="/wiki/GJC3" title="GJC3">GJC3</a></li> <li><a href="/wiki/GNB2" title="GNB2">GNB2</a></li> <li><a href="/wiki/SFRP4" title="SFRP4">SFRP4</a></li> <li><a href="/wiki/HOXA6" title="HOXA6">HOXA6</a></li> <li><a href="/wiki/KMT2E" title="KMT2E">KMT2E</a></li> <li><a href="/wiki/LSM5" title="LSM5">LSM5</a></li> <li><a href="/wiki/TRA2A" title="TRA2A">TRA2A</a></li> <li><a href="/wiki/CLCN1" title="CLCN1">CLCN1</a></li> <li><a href="/wiki/IRF5" title="IRF5">IRF5</a></li> <li><a href="/wiki/HRBL" title="HRBL">HRBL</a></li> <li><a href="/wiki/CPED1" title="CPED1">CPED1</a></li> <li><a href="/wiki/PRSS2" title="PRSS2">PRSS2</a></li> <li><a href="/wiki/GNG11" title="GNG11">GNG11</a></li> <li><a href="/wiki/CYTH3" title="CYTH3">CYTH3</a></li> <li><a href="/wiki/NUB1" title="NUB1">NUB1</a></li> <li><a href="/wiki/PCLO" title="PCLO">PCLO</a></li> <li><a href="/wiki/SEC61G" title="SEC61G">SEC61G</a></li> <li><a href="/wiki/SEMA3C" title="SEMA3C">SEMA3C</a></li> <li><a href="/wiki/SMARCD3" title="SMARCD3">SMARCD3</a></li> <li><a href="/wiki/NPTX2" title="NPTX2">NPTX2</a></li> <li><a href="/wiki/HOXA11" title="HOXA11">HOXA11</a></li> <li><a href="/wiki/ORC5" title="ORC5">ORC5</a></li> <li><a href="/wiki/PEX1" title="PEX1">PEX1</a></li> <li><a href="/wiki/NUDCD3" title="NUDCD3">NUDCD3</a></li> <li><a href="/wiki/MRPS33" title="MRPS33">MRPS33</a></li> <li><a href="/wiki/RINT1" title="RINT1">RINT1</a></li> <li><a href="/wiki/SEPT7" title="SEPT7">SEPT7</a></li> <li><a href="/wiki/CPSF4" title="CPSF4">CPSF4</a></li> <li><a href="/wiki/ZP3" title="ZP3">ZP3</a></li> <li><a href="/wiki/MPP6" title="MPP6">MPP6</a></li> <li><a href="/wiki/DFNA5" title="DFNA5">DFNA5</a></li> <li><a href="/wiki/CCT6A" title="CCT6A">CCT6A</a></li> <li><a href="/wiki/IGFBP1" title="IGFBP1">IGFBP1</a></li> <li><a href="/wiki/CLDN12" title="CLDN12">CLDN12</a></li> <li><a href="/wiki/FAM62B" title="FAM62B">FAM62B</a></li> <li><a href="/wiki/TMED4" title="TMED4">TMED4</a></li> <li><a href="/wiki/MEOX2" title="MEOX2">MEOX2</a></li> <li><a href="/wiki/PPP1R17" title="PPP1R17">PPP1R17</a></li> <li><a href="/wiki/MTPN" title="MTPN">MTPN</a></li> <li><a href="/wiki/COG5" title="COG5">COG5</a></li> <li><a href="/wiki/NOM1" title="NOM1">NOM1</a></li> <li><a href="/wiki/PILRA" title="PILRA">PILRA</a></li> <li><a href="/wiki/CADPS2" title="CADPS2">CADPS2</a></li> <li><a href="/wiki/Drebrin-like" title="Drebrin-like">Drebrin-like</a></li> <li><a href="/wiki/EIF3B" title="EIF3B">EIF3B</a></li> <li><a href="/wiki/BRAT1" title="BRAT1">BRAT1</a></li> <li><a href="/wiki/ZNF655" title="ZNF655">ZNF655</a></li> <li><a href="/wiki/FSCN3" title="FSCN3">FSCN3</a></li> <li><a href="/wiki/TSPAN13" title="TSPAN13">TSPAN13</a></li> <li><a href="/wiki/YKT6" title="YKT6">YKT6</a></li> <li><a href="/wiki/ARHGEF35" title="ARHGEF35">ARHGEF35</a></li> <li><a href="/wiki/ERV3" title="ERV3">ERV3</a></li> <li><a href="/wiki/TFEC" title="TFEC">TFEC</a></li> <li><a href="/wiki/ZSCAN21" title="ZSCAN21">ZSCAN21</a></li> <li><a href="/wiki/TMEM130" title="TMEM130">TMEM130</a></li> <li><a class="mw-selflink selflink">ABCB4</a></li> <li><a href="/wiki/LRRC17" title="LRRC17">LRRC17</a></li> <li><a href="/wiki/AOAH" title="AOAH">AOAH</a></li> <li><a href="/wiki/GLCCI1" title="GLCCI1">GLCCI1</a></li> <li><a href="/wiki/TMEM196" title="TMEM196">TMEM196</a></li> <li><a href="/wiki/ARPC1A" title="ARPC1A">ARPC1A</a></li> <li><a href="/wiki/RSPH10B" title="RSPH10B">RSPH10B</a></li> <li><a href="/wiki/IGF2BP3" title="IGF2BP3">IGF2BP3</a></li> <li><a href="/wiki/ZKSCAN1" title="ZKSCAN1">ZKSCAN1</a></li> <li><a href="/wiki/PKD1L1" title="PKD1L1">PKD1L1</a></li> <li><a href="/wiki/GET4" title="GET4">GET4</a></li> <li><a href="/wiki/ZNF3" title="ZNF3">ZNF3</a></li> <li><a href="/wiki/NOD1" title="NOD1">NOD1</a></li> <li><a href="/wiki/SSBP1" title="SSBP1">SSBP1</a></li> <li><a href="/wiki/STK17A" title="STK17A">STK17A</a></li> <li><a href="/wiki/SLC12A9" title="SLC12A9">SLC12A9</a></li> <li><a href="/wiki/DDX56" title="DDX56">DDX56</a></li> <li><a href="/wiki/AP4M1" title="AP4M1">AP4M1</a></li> <li><a href="/wiki/ZC3HAV1" title="ZC3HAV1">ZC3HAV1</a></li> <li><a href="/wiki/ING3" title="ING3">ING3</a></li> <li><a href="/wiki/NCAPG2" title="NCAPG2">NCAPG2</a></li> <li><a href="/wiki/ZKSCAN5" title="ZKSCAN5">ZKSCAN5</a></li> <li><a href="/wiki/ZNF277P" title="ZNF277P">ZNF277P</a></li> <li><a href="/wiki/LUC7L2" title="LUC7L2">LUC7L2</a></li> <li><a href="/wiki/CLDN3" title="CLDN3">CLDN3</a></li> <li><a href="/wiki/FSCN1" title="FSCN1">FSCN1</a></li> <li><a href="/wiki/Caldesmon" title="Caldesmon">Caldesmon</a></li> <li><a href="/wiki/FBXO24" title="FBXO24">FBXO24</a></li> <li><a href="/wiki/LMBR1" title="LMBR1">LMBR1</a></li> <li><a href="/wiki/Transportin-3" title="Transportin-3">Transportin-3</a></li> <li><a href="/wiki/PLEKHA8" title="PLEKHA8">PLEKHA8</a></li> <li><a href="/wiki/ARL4A" title="ARL4A">ARL4A</a></li> <li><a href="/wiki/MPLKIP" title="MPLKIP">MPLKIP</a></li> <li><a href="/wiki/KDM7A" title="KDM7A">KDM7A</a></li> <li><a href="/wiki/SCRN1" title="SCRN1">SCRN1</a></li> <li><a href="/wiki/EMID2" title="EMID2">EMID2</a></li> <li><a href="/wiki/SPDYE1" title="SPDYE1">SPDYE1</a></li> <li><a href="/wiki/GNA12" title="GNA12">GNA12</a></li> <li><a href="/wiki/PDAP1" title="PDAP1">PDAP1</a></li> <li><a href="/wiki/CNOT4" title="CNOT4">CNOT4</a></li> <li><a href="/wiki/AZGP1" title="AZGP1">AZGP1</a></li> <li><a href="/wiki/PAX4" title="PAX4">PAX4</a></li> <li><a href="/wiki/RBM28" title="RBM28">RBM28</a></li> <li><a href="/wiki/JAZF1" title="JAZF1">JAZF1</a></li> <li><a href="/wiki/BET1" title="BET1">BET1</a></li> <li><a href="/wiki/NUPL2" title="NUPL2">NUPL2</a></li> <li><a href="/wiki/CTTNBP2" title="CTTNBP2">CTTNBP2</a></li> <li><a href="/wiki/GTF2IRD1" title="GTF2IRD1">GTF2IRD1</a></li> <li><a href="/wiki/RBM33" title="RBM33">RBM33</a></li> <li><a href="/wiki/LAMTOR4" title="LAMTOR4">LAMTOR4</a></li> <li><a href="/wiki/STYXL1" title="STYXL1">STYXL1</a></li> <li><a href="/wiki/FEZF1" title="FEZF1">FEZF1</a></li> <li><a href="/wiki/GCC1" title="GCC1">GCC1</a></li> <li><a href="/wiki/TMEM106B" title="TMEM106B">TMEM106B</a></li> <li><a href="/wiki/MRPL32" title="MRPL32">MRPL32</a></li> <li><a href="/wiki/INTS1" title="INTS1">INTS1</a></li> <li><a href="/wiki/PAXIP1" title="PAXIP1">PAXIP1</a></li> <li><a href="/wiki/ZMIZ2" title="ZMIZ2">ZMIZ2</a></li> <li><a href="/wiki/MNX1" title="MNX1">MNX1</a></li> <li><a href="/wiki/POM121" title="POM121">POM121</a></li> <li><a href="/wiki/RP9" title="RP9">RP9</a></li> <li><a href="/wiki/FOXK1" title="FOXK1">FOXK1</a></li> <li><a href="/wiki/IQCE" title="IQCE">IQCE</a></li> <li><a href="/wiki/CYP2W1" title="CYP2W1">CYP2W1</a></li> <li><a href="/wiki/HOXA13" title="HOXA13">HOXA13</a></li> <li><a href="/wiki/SYPL1" title="SYPL1">SYPL1</a></li> <li><a href="/wiki/SSC4D" title="SSC4D">SSC4D</a></li> <li><a href="/wiki/TRIP6" title="TRIP6">TRIP6</a></li> <li><a href="/wiki/PVRIG" title="PVRIG">PVRIG</a></li> <li><a href="/wiki/WNT16" title="WNT16">WNT16</a></li> <li><a href="/wiki/FKBP9" title="FKBP9">FKBP9</a></li> <li><a href="/wiki/Beta-actin" title="Beta-actin">Beta-actin</a></li> <li><a href="/wiki/SAMD9" title="SAMD9">SAMD9</a></li> <li><a href="/wiki/ARHGEF5" title="ARHGEF5">ARHGEF5</a></li> <li><a href="/wiki/KDELR2" title="KDELR2">KDELR2</a></li> <li><a href="/wiki/CHCHD2" title="CHCHD2">CHCHD2</a></li> <li><a href="/wiki/PEG10" title="PEG10">PEG10</a></li> <li><a href="/wiki/SDK1" title="SDK1">SDK1</a></li> <li><a href="/wiki/SOSTDC1" title="SOSTDC1">SOSTDC1</a></li> <li><a href="/wiki/HOXA2" title="HOXA2">HOXA2</a></li> <li><a href="/wiki/BAIAP2L1" title="BAIAP2L1">BAIAP2L1</a></li> <li><a href="/wiki/LRRC4" title="LRRC4">LRRC4</a></li> <li><a href="/wiki/LAT2" title="LAT2">LAT2</a></li> <li><a href="/wiki/CCM2" title="CCM2">CCM2</a></li> <li><a href="/wiki/DPP6" title="DPP6">DPP6</a></li> <li><a href="/wiki/RADIL" title="RADIL">RADIL</a></li> <li><a href="/wiki/TAF6" title="TAF6">TAF6</a></li> <li><a href="/wiki/MOGAT3" title="MOGAT3">MOGAT3</a></li> <li><a href="/wiki/CCL24" title="CCL24">CCL24</a></li> <li><a href="/wiki/SCIN" title="SCIN">SCIN</a></li> <li><a href="/wiki/ETV1" title="ETV1">ETV1</a></li> <li><a href="/wiki/GNAT3" title="GNAT3">GNAT3</a></li> <li><a href="/wiki/CREB5" title="CREB5">CREB5</a></li> <li><a href="/wiki/HEPACAM2" title="HEPACAM2">HEPACAM2</a></li> <li><a href="/wiki/PDGFA" title="PDGFA">PDGFA</a></li> <li><a href="/wiki/BCAP29" title="BCAP29">BCAP29</a></li> <li><a href="/wiki/KLF14" title="KLF14">KLF14</a></li> <li><a href="/wiki/LANCL2" title="LANCL2">LANCL2</a></li> <li><a href="/wiki/FAM3C" title="FAM3C">FAM3C</a></li> <li><a href="/wiki/TMEM176B" title="TMEM176B">TMEM176B</a></li> <li><a href="/wiki/DLX6" title="DLX6">DLX6</a></li> <li><a href="/wiki/HOXA4" title="HOXA4">HOXA4</a></li> <li><a href="/wiki/CYP3A43" title="CYP3A43">CYP3A43</a></li> <li><a href="/wiki/CLDN4" title="CLDN4">CLDN4</a></li> <li><a href="/wiki/RNF32" title="RNF32">RNF32</a></li> <li><a href="/wiki/DLX5" title="DLX5">DLX5</a></li> <li><a href="/wiki/LSM8" title="LSM8">LSM8</a></li> <li><a href="/wiki/MRPS17" title="MRPS17">MRPS17</a></li> <li><a href="/wiki/ATP6V1F" title="ATP6V1F">ATP6V1F</a></li> <li><a href="/wiki/CALN1" title="CALN1">CALN1</a></li> <li><a href="/wiki/%D8%AC%D8%B2%D9%8A%D8%A6%D8%A7%D8%AA_%D8%A7%D9%84%D8%AA%D8%B5%D8%A7%D9%82_%D8%A7%D9%84%D8%AE%D9%84%D8%A7%D9%8A%D8%A7_%D8%A7%D9%84%D8%B9%D8%B5%D8%A8%D9%88%D9%86%D9%8A%D8%A9" title="جزيئات التصاق الخلايا العصبونية">جزيئات التصاق الخلايا العصبونية</a></li> <li><a href="/wiki/NOBOX" title="NOBOX">NOBOX</a></li> <li><a href="/wiki/MRPS24" title="MRPS24">MRPS24</a></li> <li><a href="/wiki/FAM20C" title="FAM20C">FAM20C</a></li> <li><a href="/wiki/COPS6" title="COPS6">COPS6</a></li> <li><a href="/wiki/DMTF1" title="DMTF1">DMTF1</a></li> <li><a href="/wiki/PILRB" title="PILRB">PILRB</a></li> <li><a href="/wiki/AUTS2" title="AUTS2">AUTS2</a></li> <li><a href="/wiki/HOXA5" title="HOXA5">HOXA5</a></li> <li><a href="/wiki/ST7" title="ST7">ST7</a></li> <li><a href="/wiki/MTERF" title="MTERF">MTERF</a></li> <li><a href="/wiki/STEAP4" title="STEAP4">STEAP4</a></li> <li><a href="/wiki/WIPI2" title="WIPI2">WIPI2</a></li> <li><a href="/wiki/C7orf31" title="C7orf31">C7orf31</a></li> <li><a href="/wiki/CNTNAP2" title="CNTNAP2">CNTNAP2</a></li> <li><a href="/wiki/GNGT1" title="GNGT1">GNGT1</a></li> <li><a href="/wiki/HECW1" title="HECW1">HECW1</a></li> <li><a href="/wiki/SEPT14" title="SEPT14">SEPT14</a></li> <li><a href="/wiki/POT1" title="POT1">POT1</a></li> <li><a href="/wiki/OSBPL3" title="OSBPL3">OSBPL3</a></li> <li><a href="/wiki/PURB" title="PURB">PURB</a></li> <li><a href="/wiki/DYNC1I1" title="DYNC1I1">DYNC1I1</a></li> <li><a href="/wiki/HOXA3" title="HOXA3">HOXA3</a></li> <li><a href="/wiki/HBP1" title="HBP1">HBP1</a></li> <li><a href="/wiki/MTRNR2L6" title="MTRNR2L6">MTRNR2L6</a></li> <li><a href="/wiki/PPP1R9A" title="PPP1R9A">PPP1R9A</a></li> <li><a href="/wiki/PHTF2" title="PHTF2">PHTF2</a></li> <li><a href="/wiki/Calumenin" title="Calumenin">Calumenin</a></li> <li><a href="/wiki/H2AFV" title="H2AFV">H2AFV</a></li> <li><a href="/wiki/DNAJB9" title="DNAJB9">DNAJB9</a></li> <li><a href="/wiki/ATG9B" title="ATG9B">ATG9B</a></li> <li><a href="/wiki/Muskelin" title="Muskelin">Muskelin</a></li> <li><a href="/wiki/TMEM243" title="TMEM243">TMEM243</a></li> <li><a href="/wiki/EXOC4" title="EXOC4">EXOC4</a></li> <li><a href="/wiki/ACTL6B" title="ACTL6B">ACTL6B</a></li> <li><a href="/wiki/NME8" title="NME8">NME8</a></li> <li><a href="/wiki/HOXA7" title="HOXA7">HOXA7</a></li> <li><a href="/wiki/SGCE" title="SGCE">SGCE</a></li> <li><a href="/wiki/AGR3" title="AGR3">AGR3</a></li> <li><a href="/wiki/EPHB6" title="EPHB6">EPHB6</a></li> <li><a href="/wiki/LRCH4" title="LRCH4">LRCH4</a></li> <li><a href="/wiki/ELMO1" title="ELMO1">ELMO1</a></li> <li><a href="/wiki/PTPRN2" title="PTPRN2">PTPRN2</a></li> <li><a href="/wiki/CLIP2" title="CLIP2">CLIP2</a></li> <li><a href="/wiki/NXPH1" title="NXPH1">NXPH1</a></li> <li><a href="/wiki/TAX1BP1" title="TAX1BP1">TAX1BP1</a></li></ul> </div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r68268331">.mw-parser-output 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#liste-portail{padding:3px;text-align:center;margin-right:0;clear:both}.mw-parser-output #liste-portail li,.mw-parser-output #bandeau-portail li{display:inline}.mw-parser-output .bandeau-portail-element{white-space:nowrap;margin:auto 1.5em}.mw-parser-output .bandeau-portail-icone{margin-left:0.5em}.mw-parser-output .bandeau-portail-texte>a:nth-child(1){font-weight:700}.mw-parser-output .ns-14 #bandeau-portail{width:242px;float:left;font-size:96%;text-align:right;margin:0;clear:left}.mw-parser-output .ns-14 #bandeau-portail li{margin-right:-17px}@media screen{html.skin-theme-clientpref-night .mw-parser-output .portalbox{background:transparent}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .pane{background:transparent}}</style><ul role="navigation" aria-label="Portals" class="noprint bandeau-portail" id="bandeau-portail"> <li class="bandeau-portail-element"><span class="bandeau-portail-icone"><span class="noviewer" typeof="mw:File"><a 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srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/1a/Biological_cell.svg/48px-Biological_cell.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/1a/Biological_cell.svg/64px-Biological_cell.svg.png 2x" data-file-width="1466" data-file-height="891" /></a></span></span><span class="bandeau-portail-texte"><a href="/wiki/%D8%A8%D9%88%D8%A7%D8%A8%D8%A9:%D8%B9%D9%84%D9%85_%D8%A7%D9%84%D8%A3%D8%AD%D9%8A%D8%A7%D8%A1_%D8%A7%D9%84%D8%AE%D9%84%D9%88%D9%8A_%D9%88%D8%A7%D9%84%D8%AC%D8%B2%D9%8A%D8%A6%D9%8A" title="بوابة:علم الأحياء الخلوي والجزيئي">بوابة علم الأحياء الخلوي والجزيئي</a></span></li></ul> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r64177691"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r68124052"></div><div role="navigation" class="navbox" aria-label="Navbox" style="padding:1px"><table class="nowraplinks hlist navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="row" class="navbox-group" style="width:12%">التصنيفات الطبية</th><td class="navbox-list-with-group navbox-list navbox-odd" style="padding:0;text-align:right;"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/%D8%A7%D9%84%D9%88%D8%B1%D8%A7%D8%AB%D8%A9_%D8%A7%D9%84%D9%85%D9%86%D8%AF%D9%84%D9%8A%D8%A9_%D8%A7%D9%84%D8%A8%D8%B4%D8%B1%D9%8A%D8%A9_%D8%B9%D8%A8%D8%B1_%D8%A7%D9%84%D8%A5%D9%86%D8%AA%D8%B1%D9%86%D8%AA" title="الوراثة المندلية البشرية عبر الإنترنت">دليل الوراثة المندلية عند البشر (OMIM)</a></b>: <a rel="nofollow" class="external text" href="https://omim.org/entry/171060">171060</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:12%">المعرفات الخارجية</th><td class="navbox-list-with-group navbox-list navbox-even" style="padding:0;text-align:right;"><div style="padding:0 0.25em"> <ul><li><b><a href="/wiki/%D9%85%D8%B4%D8%B1%D9%88%D8%B9_%D9%82%D8%A7%D8%B9%D8%AF%D8%A9_%D8%A8%D9%8A%D8%A7%D9%86%D8%A7%D8%AA_%D8%AC%D9%8A%D9%86%D9%88%D9%85_%D8%A5%D9%86%D8%B3%D9%86%D8%A8%D9%84" title="مشروع قاعدة بيانات جينوم إنسنبل">Ensembl Transcript ID</a></b>: <a rel="nofollow" class="external text" href="http://identifiers.org/ensembl/ENST00000649586">ENST00000649586</a></li> <li><b><a href="/wiki/%D9%86%D8%B8%D8%A7%D9%85_%D8%A7%D9%84%D9%84%D8%BA%D8%A9_%D8%A7%D9%84%D8%B7%D8%A8%D9%8A%D8%A9_%D8%A7%D9%84%D9%85%D9%88%D8%AD%D8%AF%D8%A9" title="نظام اللغة الطبية الموحدة">نظام اللغة الطبية الموحدة (UMLS CUI)</a></b>: <a rel="nofollow" class="external text" href="https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C1412071">C1412071</a></li></ul> </div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r64185208">.mw-parser-output .asbox{position:relative;overflow:hidden;background-color:#f9f9f9;border:solid 1px #C0C0C0}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-size:95%}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/%D9%85%D9%84%D9%81:DNA_stub.png" class="mw-file-description"><img alt="أيقونة بذرة" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/26px-DNA_stub.png" decoding="async" width="26" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/40px-DNA_stub.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/53px-DNA_stub.png 2x" data-file-width="816" data-file-height="621" /></a></span></td><td><p class="asbox-body">هذه <a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%A8%D8%B0%D8%B1%D8%A9" title="ويكيبيديا:بذرة">بذرة</a> مقالة عن <a href="/wiki/%D8%AC%D9%8A%D9%86" title="جين">جين</a> على <a href="/wiki/%D8%B5%D8%A8%D8%BA%D9%8A_7" title="صبغي 7">كروموسوم 7</a> بحاجة للتوسيع. فضلًا <a class="external text" href="https://ar.wikipedia.org/w/index.php?title=ABCB4&action=edit">شارك</a> في تحريرها.</p></td></tr></tbody></table></div></div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">مجلوبة من «<a dir="ltr" href="https://ar.wikipedia.org/w/index.php?title=ABCB4&oldid=60739278">https://ar.wikipedia.org/w/index.php?title=ABCB4&oldid=60739278</a>»</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/%D9%88%D9%8A%D9%83%D9%8A%D8%A8%D9%8A%D8%AF%D9%8A%D8%A7:%D8%AA%D8%B5%D9%81%D8%AD" title="ويكيبيديا:تصفح">تصنيف</a>: <ul><li><a href="/wiki/%D8%AA%D8%B5%D9%86%D9%8A%D9%81:%D8%AC%D9%8A%D9%86%D8%A7%D8%AA_%D8%B9%D9%84%D9%89_%D9%83%D8%B1%D9%88%D9%85%D9%88%D8%B3%D9%88%D9%85_7" title="تصنيف:جينات على كروموسوم 7">جينات على كروموسوم 7</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">تصنيفات مخفية: <ul><li><a href="/wiki/%D8%AA%D8%B5%D9%86%D9%8A%D9%81:Pages_using_the_JsonConfig_extension" title="تصنيف:Pages using the JsonConfig extension">Pages using the JsonConfig extension</a></li><li><a href="/wiki/%D8%AA%D8%B5%D9%86%D9%8A%D9%81:%D9%85%D9%82%D8%A7%D9%84%D8%A7%D8%AA_%D8%AA%D8%B3%D8%AA%D8%B9%D9%85%D9%84_%D9%82%D9%88%D8%A7%D9%84%D8%A8_%D9%85%D8%B9%D9%84%D9%88%D9%85%D8%A7%D8%AA" title="تصنيف:مقالات تستعمل قوالب معلومات">مقالات تستعمل قوالب معلومات</a></li><li><a href="/wiki/%D8%AA%D8%B5%D9%86%D9%8A%D9%81:%D9%85%D9%82%D8%A7%D9%84%D8%A7%D8%AA_%D8%A8%D9%87%D8%A7_%D8%A3%D9%82%D8%B3%D8%A7%D9%85_%D9%81%D8%A7%D8%B1%D8%BA%D8%A9_%D9%85%D9%86%D8%B0_%D9%8A%D9%88%D9%84%D9%8A%D9%88_2018" title="تصنيف:مقالات بها أقسام فارغة منذ يوليو 2018">مقالات بها أقسام فارغة منذ يوليو 2018</a></li><li><a href="/wiki/%D8%AA%D8%B5%D9%86%D9%8A%D9%81:%D8%AC%D9%85%D9%8A%D8%B9_%D8%A7%D9%84%D9%85%D9%82%D8%A7%D9%84%D8%A7%D8%AA_%D8%A7%D9%84%D8%AA%D9%8A_%D8%A8%D9%87%D8%A7_%D8%A3%D9%82%D8%B3%D8%A7%D9%85_%D9%81%D8%A7%D8%B1%D8%BA%D8%A9" title="تصنيف:جميع المقالات التي بها أقسام فارغة">جميع المقالات التي بها أقسام فارغة</a></li><li><a href="/wiki/%D8%AA%D8%B5%D9%86%D9%8A%D9%81:%D8%AC%D9%85%D9%8A%D8%B9_%D8%A7%D9%84%D9%85%D9%82%D8%A7%D9%84%D8%A7%D8%AA_%D8%A7%D9%84%D8%AA%D9%8A_%D8%A8%D8%AD%D8%A7%D8%AC%D8%A9_%D9%84%D8%B5%D9%8A%D8%A7%D9%86%D8%A9" title="تصنيف:جميع المقالات التي بحاجة لصيانة">جميع المقالات التي بحاجة لصيانة</a></li><li><a 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