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fracture</title> <meta name="description" content="Search results for: bone fracture"> <meta name="keywords" content="bone fracture"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="bone fracture"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 1336</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: bone fracture</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1336</span> A Radiographic Survey of Eggshell Powder Effect on Tibial Bone Defect Repair Tested in Dog</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Yadegari">M. Yadegari</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Nourbakhsh"> M. Nourbakhsh</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Arbabzadeh"> N. Arbabzadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The skeletal system injuries are of major importance. In addition, it is recommended to use materials for hard tissue repair in open or closed fractures. It is important to use complex minerals with a beneficial effect on hard tissue repair, stimulating cell growth in the bone. Materials that could help avoid bone fracture inflammatory reaction and speed up bone fracture repair are of utmost importance in the treatment of bone fractures. Similar to minerals, the inner eggshell membrane consists of carbohydrates, lipids, proteins with the high pH, high calcium absorptive capacity and with faster bone fracture repair ability. In the present radiographic survey, eggshell-derived bone graft substitutes were used for bone defect repair in 8 dog tibia, measuring bone density on the day of implant placement and 30 and 60 days after placement. In fact, the result of this study shows the difference in bone growth and misshapen bones between treatment and control sites. Cell growth was adequate in treatment sites and misshapen bones were less frequent here than in control sites. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20repair" title="bone repair">bone repair</a>, <a href="https://publications.waset.org/abstracts/search?q=eggshell%20powder" title=" eggshell powder"> eggshell powder</a>, <a href="https://publications.waset.org/abstracts/search?q=implant" title=" implant"> implant</a>, <a href="https://publications.waset.org/abstracts/search?q=radiography" title=" radiography"> radiography</a> </p> <a href="https://publications.waset.org/abstracts/34008/a-radiographic-survey-of-eggshell-powder-effect-on-tibial-bone-defect-repair-tested-in-dog" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34008.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">322</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1335</span> Bone Fracture Detection with X-Ray Images Using Mobilenet V3 Architecture</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ashlesha%20Khanapure">Ashlesha Khanapure</a>, <a href="https://publications.waset.org/abstracts/search?q=Harsh%20Kashyap"> Harsh Kashyap</a>, <a href="https://publications.waset.org/abstracts/search?q=Abhinav%20Anand"> Abhinav Anand</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanjana%20Habib"> Sanjana Habib</a>, <a href="https://publications.waset.org/abstracts/search?q=Anupama%20Bidargaddi"> Anupama Bidargaddi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Technologies that are developing quickly are being developed daily in a variety of disciplines, particularly the medical field. For the purpose of detecting bone fractures in X-ray pictures of different body segments, our work compares the ResNet-50 and MobileNetV3 architectures. It evaluates accuracy and computing efficiency with X-rays of the elbow, hand, and shoulder from the MURA dataset. Through training and validation, the models are evaluated on normal and fractured images. While ResNet-50 showcases superior accuracy in fracture identification, MobileNetV3 showcases superior speed and resource optimization. Despite ResNet-50’s accuracy, MobileNetV3’s swifter inference makes it a viable choice for real-time clinical applications, emphasizing the importance of balancing computational efficiency and accuracy in medical imaging. We created a graphical user interface (GUI) for MobileNet V3 model bone fracture detection. This research underscores MobileNetV3’s potential to streamline bone fracture diagnoses, potentially revolutionizing orthopedic medical procedures and enhancing patient care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CNN" title="CNN">CNN</a>, <a href="https://publications.waset.org/abstracts/search?q=MobileNet%20V3" title=" MobileNet V3"> MobileNet V3</a>, <a href="https://publications.waset.org/abstracts/search?q=ResNet-50" title=" ResNet-50"> ResNet-50</a>, <a href="https://publications.waset.org/abstracts/search?q=healthcare" title=" healthcare"> healthcare</a>, <a href="https://publications.waset.org/abstracts/search?q=MURA" title=" MURA"> MURA</a>, <a href="https://publications.waset.org/abstracts/search?q=X-ray" title=" X-ray"> X-ray</a>, <a href="https://publications.waset.org/abstracts/search?q=fracture%20detection" title=" fracture detection"> fracture detection</a> </p> <a href="https://publications.waset.org/abstracts/182019/bone-fracture-detection-with-x-ray-images-using-mobilenet-v3-architecture" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/182019.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">65</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1334</span> Experimental Research on the Elastic Modulus of Bones at the Lamellar Level under Fatigue Loading</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Xianjia%20Meng">Xianjia Meng</a>, <a href="https://publications.waset.org/abstracts/search?q=Chuanyong%20Qu"> Chuanyong Qu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Compact bone produces fatigue damage under the inevitable physiological load. The accumulation of fatigue damage can change the bone’s micro-structure at different scales and cause the catastrophic failure eventually. However, most tests were limited to the macroscopic modulus of bone and there is a need to assess the microscopic modulus during fatigue progress. In this paper, nano-identation was used to investigate the bone specimen subjected to four point bending. The microscopic modulus of the same area were measured at different degrees of damage including fracture. So microscopic damage can be divided into three stages: first, the modulus decreased rapidly and then They fell slowly, before fracture the decline became fast again. After fracture, the average modulus decreased by 20%. The results of inner and outer planes explained the influence of compressive and tensile loads on modulus. Both the compressive and tensile moduli decreased with the accumulation of damage. They reached the minimum at ending and increased after fracture. The modulus evolution under different strains were revealed by the side. They all fell slowly and then fast with the accumulation of damage. The fractured results indicated that the elastic modulus decreased obviously at the high strain while decreased less at the low strain. During the fatigue progress, there was a significant difference in modulus at low degree of damage. However, the dispersed modulus tended to be similar at high degree of damage, but they became different again after the failure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fatigue%20damage" title="fatigue damage">fatigue damage</a>, <a href="https://publications.waset.org/abstracts/search?q=fracture" title=" fracture"> fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=microscopic%20modulus" title=" microscopic modulus"> microscopic modulus</a>, <a href="https://publications.waset.org/abstracts/search?q=bone" title=" bone"> bone</a>, <a href="https://publications.waset.org/abstracts/search?q=nano-identation" title=" nano-identation"> nano-identation</a> </p> <a href="https://publications.waset.org/abstracts/107066/experimental-research-on-the-elastic-modulus-of-bones-at-the-lamellar-level-under-fatigue-loading" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/107066.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">165</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1333</span> Micro-CT Assessment of Fracture Healing with Targeted Delivery of Tocotrienol in Osteoporosis Model </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Nazrun%20Shuid">Ahmad Nazrun Shuid</a>, <a href="https://publications.waset.org/abstracts/search?q=Isa%20Naina%20Mohamed"> Isa Naina Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Nurul%20Izzah%20Ibrahim"> Nurul Izzah Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Norazlina%20Mohamed"> Norazlina Mohamed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Studies have shown that oral tocotrienol, a potent vitamin E, promoted fracture healing of osteoporotic bone. In this study, tocotrienol was combined with a polymer carrier (PLGA), and injected to the fracture site. The slow and constant release of tocotrienol particles would promote fracture healing of post-menopausal osteoporosis rat model. Fracture healing was assessed using micro-CT. Twenty-four Sprague-Dawley rats were ovariectomised or sham-operated and the left tibiae were fractured and fixed with plate and screws. The fractures were created at the upper third of the left tibiae. The rats were divided into 3 groups: sham-operated (SO), ovariectomised-control (OVxC) and PLGA-incorporated tocotrienol treatment (OVx + TT) groups. After 4 weeks, the OVx + TT group showed significantly better callus fracture healing than the OVxC group. In conclusion, tocotrienol-incorporated PLGA was able to promote fracture healing of osteoporotic bone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title="osteoporosis">osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=micro-CT" title=" micro-CT"> micro-CT</a>, <a href="https://publications.waset.org/abstracts/search?q=tocotrienol" title=" tocotrienol"> tocotrienol</a>, <a href="https://publications.waset.org/abstracts/search?q=PLGA" title=" PLGA"> PLGA</a>, <a href="https://publications.waset.org/abstracts/search?q=fracture" title=" fracture"> fracture</a> </p> <a href="https://publications.waset.org/abstracts/19173/micro-ct-assessment-of-fracture-healing-with-targeted-delivery-of-tocotrienol-in-osteoporosis-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19173.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">668</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1332</span> The Decrease of Collagen or Mineral Affect the Fracture in the Turkey Long Bones</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=P.%20Vosynek">P. Vosynek</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20N%C3%A1vrat"> T. Návrat</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Pe%C4%8D"> M. Peč</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Po%C5%99%C3%ADzka"> J. Pořízka</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Divi%C5%A1"> P. Diviš</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Changes of mechanical properties and response behavior of bones is an important external sign of medical problems like osteoporosis, bone remodeling after fracture or surgery, osteointegration, or bone tissue loss of astronauts in space. Measuring of mechanical behavior of bones in physiological and osteoporotic states, quantified by different degrees of protein (collagen) and mineral loss, is thus an important topic in biomechanical research. This contribution deals with the relation between mechanical properties of the turkey long bone–tibia in physiological, demineralized, and deproteinized state. Three methods for comparison were used: densitometry, three point bending and harmonic response analysis. The results help to find correlations between the methods and estimate their possible application in medical practice. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20properties" title="bone properties">bone properties</a>, <a href="https://publications.waset.org/abstracts/search?q=long%20bone" title=" long bone"> long bone</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis"> osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=response%20behavior" title=" response behavior"> response behavior</a> </p> <a href="https://publications.waset.org/abstracts/17564/the-decrease-of-collagen-or-mineral-affect-the-fracture-in-the-turkey-long-bones" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17564.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">482</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1331</span> Trabecular Bone Radiograph Characterization Using Fractal, Multifractal Analysis and SVM Classifier</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Slim">I. Slim</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Akkari"> H. Akkari</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ben%20Abdallah"> A. Ben Abdallah</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20Bhouri"> I. Bhouri</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Hedi%20Bedoui"> M. Hedi Bedoui</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoporosis is a common disease characterized by low bone mass and deterioration of micro-architectural bone tissue, which provokes an increased risk of fracture. This work treats the texture characterization of trabecular bone radiographs. The aim was to analyze according to clinical research a group of 174 subjects: 87 osteoporotic patients (OP) with various bone fracture types and 87 control cases (CC). To characterize osteoporosis, Fractal and MultiFractal (MF) methods were applied to images for features (attributes) extraction. In order to improve the results, a new method of MF spectrum based on the q-stucture function calculation was proposed and a combination of Fractal and MF attributes was used. The Support Vector Machines (SVM) was applied as a classifier to distinguish between OP patients and CC subjects. The features fusion (fractal and MF) allowed a good discrimination between the two groups with an accuracy rate of 96.22%. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fractal" title="fractal">fractal</a>, <a href="https://publications.waset.org/abstracts/search?q=micro-architecture%20analysis" title=" micro-architecture analysis"> micro-architecture analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=multifractal" title=" multifractal"> multifractal</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis"> osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=SVM" title=" SVM"> SVM</a> </p> <a href="https://publications.waset.org/abstracts/85718/trabecular-bone-radiograph-characterization-using-fractal-multifractal-analysis-and-svm-classifier" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85718.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">393</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1330</span> Improval of Fracture Healing of Osteoporotic Bone by Lovastatin-Incorporated Poly-(DL-Lactide)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nurul%20Izzah%20Ibrahim">Nurul Izzah Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Isa%20Naina%20Mohamed"> Isa Naina Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Norazlina%20Mohamed"> Norazlina Mohamed</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Nazrun%20Shuid"> Ahmad Nazrun Shuid</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoporosis disease delays fracture healing. Statins have shown potential for osteoporosis and to promote fracture healing. The effects of statin can be further potentiated by combining it with a carrier known as poly-(DL-lactide), which would provide persistent release of statin to the fracture site. This study was designed to investigate the effects of direct injection of poly-(DL-lactide)-incorporated lovastatin on fracture healing of postmenopausal osteoporosis rat model. Twenty-four Sprague-Dawley female rats were divided into 3 groups: sham-operated (SO), ovariectomized-control rats (OVxC) and poly-(DL-lactide)-incorporated lovastatin (OVx+Lov) groups. The OVx+Lov group was given a single injection of 750 µg/kg lovastatin particles incorporated with poly-(DL-lactide). After 4 weeks, the fractured tibiae were dissected out for biomechanical assessments of the callus. The OVx+Lov group showed significantly better callus strength than the OVxC group (p<0.05). In conclusion, a single injection of lovastatin-incorporated poly-(DL-lactide) was able to promote better fracture healing of osteoporotic bone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=statins" title="statins">statins</a>, <a href="https://publications.waset.org/abstracts/search?q=fracture%20healing" title=" fracture healing"> fracture healing</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis"> osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=poly-%28DL-lactide%29" title=" poly-(DL-lactide)"> poly-(DL-lactide)</a> </p> <a href="https://publications.waset.org/abstracts/9413/improval-of-fracture-healing-of-osteoporotic-bone-by-lovastatin-incorporated-poly-dl-lactide" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9413.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">506</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1329</span> Effect of Aerobic Exercise on Estrogen Hormone and Bone Mineral Density in Osteoporotic Women</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noha%20Mohamed%20Abdelhafez%20Dahy">Noha Mohamed Abdelhafez Dahy</a>, <a href="https://publications.waset.org/abstracts/search?q=Azza%20Abd%20El-Aziz"> Azza Abd El-Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=Eman%20Ahmed"> Eman Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Marwa%20El-Sayed"> Marwa El-Sayed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoporosis is a metabolic bone disease characterized by low bone mass, deterioration of bone tissue, and disruption of bone microarchitecture, which leads to compromised bone strength and an increased risk of fracture, commonly it occurs in women 10-15 years after menopause, the mean age of menopause is 51 years. Menopause is natural physiological changes primary because of decline of ovaries function with age which leads to decrease of estrogen hormone production which is the main hormone for bone continuous remodeling for bone density maintenance. Exercise increase stimulation of bone growth to keep bone mass by the effect of the mechanical stimulation, antigravity loading and stress exerted on musculoskeletal muscles. Purpose: This study aimed to determine the effect of aerobic exercise on estrogen hormone and bone mineral density (BMD) in osteoporotic women and the correlation between the estrogen and BMD. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Osteoporosis" title="Osteoporosis">Osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=Postmenopause" title=" Postmenopause"> Postmenopause</a>, <a href="https://publications.waset.org/abstracts/search?q=Aerobic%20exercise" title=" Aerobic exercise"> Aerobic exercise</a>, <a href="https://publications.waset.org/abstracts/search?q=DEXA" title=" DEXA"> DEXA</a>, <a href="https://publications.waset.org/abstracts/search?q=Serum%20Estrogen" title=" Serum Estrogen"> Serum Estrogen</a> </p> <a href="https://publications.waset.org/abstracts/166825/effect-of-aerobic-exercise-on-estrogen-hormone-and-bone-mineral-density-in-osteoporotic-women" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166825.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">88</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1328</span> Development of an Image-Based Biomechanical Model for Assessment of Hip Fracture Risk</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Masoud%20Nasiri%20Sarvi">Masoud Nasiri Sarvi</a>, <a href="https://publications.waset.org/abstracts/search?q=Yunhua%20Luo"> Yunhua Luo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Low-trauma hip fracture, usually caused by fall from standing height, has become a main source of morbidity and mortality for the elderly. Factors affecting hip fracture include sex, race, age, body weight, height, body mass distribution, etc., and thus, hip fracture risk in fall differs widely from subject to subject. It is therefore necessary to develop a subject-specific biomechanical model to predict hip fracture risk. The objective of this study is to develop a two-level, image-based, subject-specific biomechanical model consisting of a whole-body dynamics model and a proximal-femur finite element (FE) model for more accurately assessing the risk of hip fracture in lateral falls. Required information for constructing the model is extracted from a whole-body and a hip DXA (Dual Energy X-ray Absorptiometry) image of the subject. The proposed model considers all parameters subject-specifically, which will provide a fast, accurate, and non-expensive method for predicting hip fracture risk. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20mineral%20density" title="bone mineral density">bone mineral density</a>, <a href="https://publications.waset.org/abstracts/search?q=hip%20fracture%20risk" title=" hip fracture risk"> hip fracture risk</a>, <a href="https://publications.waset.org/abstracts/search?q=impact%20force" title=" impact force"> impact force</a>, <a href="https://publications.waset.org/abstracts/search?q=sideways%20falls" title=" sideways falls "> sideways falls </a> </p> <a href="https://publications.waset.org/abstracts/34060/development-of-an-image-based-biomechanical-model-for-assessment-of-hip-fracture-risk" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34060.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">536</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1327</span> Orthopedic Trauma in Newborn Babies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Joanna%20Maj">Joanna Maj</a>, <a href="https://publications.waset.org/abstracts/search?q=Awais%20Hussain"> Awais Hussain</a>, <a href="https://publications.waset.org/abstracts/search?q=Lyndsey%20Vu"> Lyndsey Vu</a>, <a href="https://publications.waset.org/abstracts/search?q=Catherine%20Roxas"> Catherine Roxas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Bone injuries in babies are common conditions that arise during delivery. Fractures of the clavicle, humerus, femur, and skull are the most common neonatal bone injuries sustained from labor and delivery. During operative deliveries, zealous tractions, ineffective delivery techniques, improper uterine incision, and inadequate relaxation of the uterus can lead to bone fractures in the newborn. Neonatal anatomy is unique. Just as children are not mini-adults, newborns are not mini children. A newborn’s anatomy and physiology are significantly different from a pediatric patient's. In this paper, we describe common orthopedic trauma in newborn babies. We provide a comprehensive overview of the different types of bone injuries in newborns. We hypothesize that the rate of bone fractures sustained at birth is higher in cases of operative deliveries. Methods: Relevant literature was selected by using the PubMed database. Search terms included orthopedic conditions in newborns, neonatal anatomy, and bone fractures in neonates during operative deliveries. Inclusion criteria included age, gender, race, type of bone injury and progression of bone injury. Exclusion criteria were limited in the medical history of cases reviewed and comorbidities. Results: This review finds that a clavicle fracture is the most common type of neonatal orthopedic injury sustained at birth in both operative and non-operative deliveries. We confirm the hypothesis that infants born via operative deliveries have a significantly higher rate of bone fractures than non-cesarean section deliveries. Conclusion: Newborn babies born via operative deliveries have a higher rate of bone fractures of the clavicle, humerus, and femur. A clavicle bone fracture in newborns is most common during emergency operative deliveries in new mothers. We conclude that infants born via an operative delivery sustained more bone injuries than infants born via non-cesarean section deliveries. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=clavicle%20fracture" title="clavicle fracture">clavicle fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=humerus%20fracture" title=" humerus fracture"> humerus fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=neonates" title=" neonates"> neonates</a>, <a href="https://publications.waset.org/abstracts/search?q=newborn%20orthopedics" title=" newborn orthopedics"> newborn orthopedics</a>, <a href="https://publications.waset.org/abstracts/search?q=orthopedic%20surgery" title=" orthopedic surgery"> orthopedic surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=pediatrics" title=" pediatrics"> pediatrics</a>, <a href="https://publications.waset.org/abstracts/search?q=orthopedic%20trauma" title=" orthopedic trauma"> orthopedic trauma</a>, <a href="https://publications.waset.org/abstracts/search?q=orthopedic%20trauma%20during%20delivery" title=" orthopedic trauma during delivery"> orthopedic trauma during delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=cesarean%20section" title=" cesarean section"> cesarean section</a>, <a href="https://publications.waset.org/abstracts/search?q=obstetrics" title=" obstetrics"> obstetrics</a>, <a href="https://publications.waset.org/abstracts/search?q=neonatal%20anatomy" title=" neonatal anatomy"> neonatal anatomy</a>, <a href="https://publications.waset.org/abstracts/search?q=neonatal%20fractures" title=" neonatal fractures"> neonatal fractures</a>, <a href="https://publications.waset.org/abstracts/search?q=operative%20deliveries" title=" operative deliveries"> operative deliveries</a>, <a href="https://publications.waset.org/abstracts/search?q=labor%20and%20delivery" title=" labor and delivery"> labor and delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20injuries%20in%20neonates" title=" bone injuries in neonates"> bone injuries in neonates</a> </p> <a href="https://publications.waset.org/abstracts/158766/orthopedic-trauma-in-newborn-babies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158766.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">101</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1326</span> Synthesis of Antibacterial Bone Cement from Re-Cycle Biowaste Containing Methylmethacrylate (MMA) Matrix</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sungging%20Pintowantoro">Sungging Pintowantoro</a>, <a href="https://publications.waset.org/abstracts/search?q=Yuli%20Setiyorini"> Yuli Setiyorini</a>, <a href="https://publications.waset.org/abstracts/search?q=Rochman%20Rochim"> Rochman Rochim</a>, <a href="https://publications.waset.org/abstracts/search?q=Agung%20Purniawan"> Agung Purniawan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The bacterial infections are frequent and undesired occurrences after bone fracture treatment. One approach to reduce the incidence of bone fracture infection is the additional of microbial agents into bone cement. In this study, the synthesis of bone cement from re-cycles biowaste was successfully conducted completed with anti-bacterial function. The re-cycle of biowaste using microwave assisted was done in our previous studies in order to produce some of powder (calcium carbonate, carbonated-hydroxyapatite and chitosan). The ratio of these powder combined with methylmethacrylate (MMA) as the matrix in bone cement were investigated using XRD, FTIR, SEM-EDX, hardness test and anti-bacterial test, respectively. From the XRD, FTIR and EDX were resulted the formation of carbonated-hydroxyapatite, calcium carbonate and chitosan. The morphology was revealed porous structure both C2H3K1L and C2H1K3L, respectively. The antibacterial activity was tested against Staphylococcus aureus (S. aureus) for 24 hours. The inhibition of S. aureus was clearly shown, the hollow zone was resulted in various distance 14.2mm, 7.5mm, and 7.7mm, respectively. The hardness test was depicted in various results, however, C2H1K3L can be achived 36.84HV which is closed to dry cancelous bone 35HV. In general, this study results was promising materials to use as bone cement materials. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomaterials" title="biomaterials">biomaterials</a>, <a href="https://publications.waset.org/abstracts/search?q=biowaste%20recycling" title=" biowaste recycling"> biowaste recycling</a>, <a href="https://publications.waset.org/abstracts/search?q=materials%20processing" title=" materials processing"> materials processing</a>, <a href="https://publications.waset.org/abstracts/search?q=microwave%20processing" title=" microwave processing"> microwave processing</a> </p> <a href="https://publications.waset.org/abstracts/51151/synthesis-of-antibacterial-bone-cement-from-re-cycle-biowaste-containing-methylmethacrylate-mma-matrix" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/51151.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">352</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1325</span> Management of Tibial Bone Defects Following Grade Three Injury in Adults</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rajendra%20Kumar%20Kanojia">Rajendra Kumar Kanojia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background; Massive bone gaps are common following road side accidents and injury to the tibia, specially open grade three fractures. It has been seen that the diaphyseal fractures in the tibia are prone to non-union, there are certain reasons known very well, like less soft tissues around the lower third tibia, less vascularity, less options of fixation of the fractures after trauma and prolonged surgical time, operation theatre time and special surgical means. Aim of study; To know the suitability of the ilizarov ring fixators in staged treatment of the fracture of the both bones leg, including tibia, we wish to see the role of ilizarov in management of open grade three fractures which have been operated and debrided, for getting the length use of ilizaorv ring in a tertiary canter is the aim of the study. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=open%20fracture" title="open fracture">open fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=staged%20management" title=" staged management"> staged management</a>, <a href="https://publications.waset.org/abstracts/search?q=ilizarov" title=" ilizarov"> ilizarov</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20grafting" title=" bone grafting"> bone grafting</a>, <a href="https://publications.waset.org/abstracts/search?q=lengthening" title=" lengthening"> lengthening</a> </p> <a href="https://publications.waset.org/abstracts/36467/management-of-tibial-bone-defects-following-grade-three-injury-in-adults" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/36467.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">307</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1324</span> Relation between Biochemical Parameters and Bone Density in Postmenopausal Women with Osteoporosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shokouh%20Momeni">Shokouh Momeni</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Reza%20Salamat"> Mohammad Reza Salamat</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%20Asghar%20Rastegari"> Ali Asghar Rastegari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Osteoporosis is the most prevalent metabolic bone disease in postmenopausal women associated with reduced bone mass and increased bone fracture. Measuring bone density in the lumbar spine and hip is a reliable measure of bone mass and can therefore specify the risk of fracture. Dual-energy X-ray absorptiometry(DXA) is an accurate non-invasive system measuring the bone density, with low margin of error and no complications. The present study aimed to investigate the relationship between biochemical parameters with bone density in postmenopausal women. Materials and methods: This cross-sectional study was conducted on 87 postmenopausal women referred to osteoporosis centers in Isfahan. Bone density was measured in the spine and hip area using DXA system. Serum levels of calcium, phosphorus, alkaline phosphatase and magnesium were measured by autoanalyzer and serum levels of vitamin D were measured by high-performance liquid chromatography(HPLC). Results: The mean parameters of calcium, phosphorus, alkaline phosphatase, vitamin D and magnesium did not show a significant difference between the two groups(P-value>0.05). In the control group, the relationship between alkaline phosphatase and BMC and BA in the spine was significant with a correlation coefficient of -0.402 and 0.258, respectively(P-value<0.05) and BMD and T-score in the femoral neck area showed a direct and significant relationship with phosphorus(Correlation=0.368; P-value=0.038). There was a significant relationship between the Z-score with calcium(Correlation=0.358; P-value=0.044). Conclusion: There was no significant relationship between the values of calcium, phosphorus, alkaline phosphatase, vitamin D and magnesium parameters and bone density (spine and hip) in postmenopaus <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title="osteoporosis">osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=menopause" title=" menopause"> menopause</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20mineral%20density" title=" bone mineral density"> bone mineral density</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20d" title=" vitamin d"> vitamin d</a>, <a href="https://publications.waset.org/abstracts/search?q=calcium" title=" calcium"> calcium</a>, <a href="https://publications.waset.org/abstracts/search?q=magnesium" title=" magnesium"> magnesium</a>, <a href="https://publications.waset.org/abstracts/search?q=alkaline%20phosphatase" title=" alkaline phosphatase"> alkaline phosphatase</a>, <a href="https://publications.waset.org/abstracts/search?q=phosphorus" title=" phosphorus"> phosphorus</a> </p> <a href="https://publications.waset.org/abstracts/158352/relation-between-biochemical-parameters-and-bone-density-in-postmenopausal-women-with-osteoporosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158352.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">176</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1323</span> A Review on Bone Grafting, Artificial Bone Substitutes and Bone Tissue Engineering</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kasun%20Gayashan%20Samarawickrama">Kasun Gayashan Samarawickrama</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone diseases, defects, and fractions are commonly seen in modern life. Since bone is regenerating dynamic living tissue, it will undergo healing process naturally, it cannot recover from major bone injuries, diseases and defects. In order to overcome them, bone grafting technique was introduced. Gold standard was the best method for bone grafting for the past decades. Due to limitations of gold standard, alternative methods have been implemented. Apart from them artificial bone substitutes and bone tissue engineering have become the emerging methods with technology for bone grafting. Many bone diseases and defects will be healed permanently with these promising techniques in future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20grafting" title="bone grafting">bone grafting</a>, <a href="https://publications.waset.org/abstracts/search?q=gold%20standard" title=" gold standard"> gold standard</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20substitutes" title=" bone substitutes"> bone substitutes</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20tissue%20engineering" title=" bone tissue engineering"> bone tissue engineering</a> </p> <a href="https://publications.waset.org/abstracts/79771/a-review-on-bone-grafting-artificial-bone-substitutes-and-bone-tissue-engineering" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79771.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">299</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1322</span> Effect of Operative Stabilization on Rib Fracture Healing in Porcine Experimental Model: A Pilot Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maria%20Stepankova">Maria Stepankova</a>, <a href="https://publications.waset.org/abstracts/search?q=Lucie%20Vistejnova"> Lucie Vistejnova</a>, <a href="https://publications.waset.org/abstracts/search?q=Pavel%20Klein"> Pavel Klein</a>, <a href="https://publications.waset.org/abstracts/search?q=Tereza%20Blassova"> Tereza Blassova</a>, <a href="https://publications.waset.org/abstracts/search?q=Marketa%20Slajerova"> Marketa Slajerova</a>, <a href="https://publications.waset.org/abstracts/search?q=Radek%20Sedlacek"> Radek Sedlacek</a>, <a href="https://publications.waset.org/abstracts/search?q=Martin%20Bartos"> Martin Bartos</a>, <a href="https://publications.waset.org/abstracts/search?q=Jaroslav%20Chlupac"> Jaroslav Chlupac</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Clinical outcome benefits of the segment rib fracture surgical therapy are well known and follow from better stabilization of the chest wall. Despite this, some authors still incline to conservative therapy and point out to possible rib fracture healing failure in connection with the bone vascular supply disturbance caused by metal plate implantation. This suggestion met neither experimental nor clinical verification and remains the object of discussion. In our pilot study we investigated the titanium plate fixation effect on the rib fracture healing in porcine model and its histological, biomechanical and radiological aspects. Materials and Method: Two porcine models (experimental group) underwent the operative chest wall stabilization with a titanium plate implantation after osteotomy. Two other porcine models (control group) were treated conservatively after osteotomy. Three weeks after surgery, all animals were sacrificed, treated ribs were explanted and the histological analysis, µCT imaging and biomechanical testing of the calluses tissue were performed. Results: In µCT imaging, experimental group showed a higher cortical bone volume compared to the control group. Histological analysis using the non-decalcified bone tissue blocks demonstrated more maturated callus with higher newly-formed osseous tissue ratio in experimental group in comparison to controls. In contrast, no significant differences in bone blood vessels supply in both groups were observed. This finding suggests that the bone blood supply in experimental group was not impaired. Biomechanical analysis using 3-point bending test demonstrated significantly higher bending stiffness and the maximum force in experimental group. Conclusion: Based on our observation, it could be concluded, that the titanium plate fixation of the rib fractures leads to faster bone callus maturation whereas does not cause the vascular supply impairment after 3 weeks and thus has a beneficial effect on the rib fracture healing. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20vascular%20supply" title="bone vascular supply">bone vascular supply</a>, <a href="https://publications.waset.org/abstracts/search?q=chest%20wall%20stabilization" title=" chest wall stabilization"> chest wall stabilization</a>, <a href="https://publications.waset.org/abstracts/search?q=fracture%20healing" title=" fracture healing"> fracture healing</a>, <a href="https://publications.waset.org/abstracts/search?q=histological%20analysis" title=" histological analysis"> histological analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=titanium%20plate%20implantation" title=" titanium plate implantation"> titanium plate implantation</a> </p> <a href="https://publications.waset.org/abstracts/121410/effect-of-operative-stabilization-on-rib-fracture-healing-in-porcine-experimental-model-a-pilot-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/121410.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">141</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1321</span> Macroscopic Anatomy of the Nutrient Foramina of Human Scaphoid Bone</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=B.%20V.%20Murlimanju">B. V. Murlimanju</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Scaphoid bone is commonly fractured among all the bones of the wrist. The fracture can damage the arteries and would cause avascular necrosis of the scaphoid. In this present study, the goal was to study the topography and number of nutrient foramina in the scaphoid bones of South Indian population. Methods: We studied 46 human scaphoid bones, among them 20 were left sided and 26 belonged to the right side. The scaphoid bones were available at the department of anatomy of our institution. The scaphoid bones were macroscopically observed for the topography and number of nutrient foramina. The data was collected, tabulated and analyzed. Results: The nutrient foramina were observed in all the scaphoid bones (100%). The locations of the foramina were over the non-articular surfaces in all these scaphoids. They were distributed over the palmar and dorsal surfaces. The foramina were found proximal as well as distal to the mid waist of the scaphoid bone. Their number ranged between 9 and 54 in each scaphoid bone. The number ranged between 2-24 over the palmar surface and 7-36 over the dorsal surface. They ranged between 2-24 proximal to the waist and 3-39 distal to the waist. Conclusion: The knowledge of arterial supply, topography of nutrient foramen and their number is essential to understand the concepts of avascular necrosis of scaphoid bone. It will be enlightening to understand the non-union of the fracture of waist of the scaphoid. The morphological data is required to the operating hand surgeon. We do believe that the present study has provided additional information about the topography and number of nutrient foramina of the human scaphoid bones. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=avascular%20necrosis" title="avascular necrosis">avascular necrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=nutrient%20foramen" title=" nutrient foramen"> nutrient foramen</a>, <a href="https://publications.waset.org/abstracts/search?q=scaphoid" title=" scaphoid"> scaphoid</a>, <a href="https://publications.waset.org/abstracts/search?q=vascular" title=" vascular"> vascular</a> </p> <a href="https://publications.waset.org/abstracts/42463/macroscopic-anatomy-of-the-nutrient-foramina-of-human-scaphoid-bone" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42463.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">269</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1320</span> Superiority of Bone Marrow Derived-Osteoblastic Cells (ALLOB®) over Bone Marrow Derived-Mesenchymal Stem Cells</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sandra%20Pietri">Sandra Pietri</a>, <a href="https://publications.waset.org/abstracts/search?q=Helene%20Dubout"> Helene Dubout</a>, <a href="https://publications.waset.org/abstracts/search?q=Sabrina%20Ena"> Sabrina Ena</a>, <a href="https://publications.waset.org/abstracts/search?q=Candice%20Hoste"> Candice Hoste</a>, <a href="https://publications.waset.org/abstracts/search?q=Enrico%20Bastianelli"> Enrico Bastianelli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone Therapeutics is a bone cell therapy company addressing high unmet medical needs in the field of bone fracture repair, more specifically in non-union and delayed-union fractures where the bone repair process is impaired. The company has developed a unique allogeneic osteoblastic cell product (ALLOB®) derived from bone marrow which is currently tested in humans in the indication of delayed-union fractures. The purpose of our study was to directly compare ALLOB® vs. non-differentiated mesenchymal stem cells (MSC) for their in vitro osteogenic characteristics and their in vivo osteogenic potential in order to determine which cellular type would be the most adapted for bone fracture repair. Methods: Healthy volunteers’ bone marrow aspirates (n=6) were expended (i) into BM-MSCs using a complete MSC culture medium or (ii) into ALLOB® cells according to its manufacturing process. Cells were characterized in vitro by morphology, immunophenotype, gene expression and differentiation potential. Additionally, their osteogenic potential was assessed in vivo in the subperiosteal calvaria bone formation model in nude mice. Results: The in vitro side-by-side comparison studies showed that although ALLOB® and BM-MSC shared some common general characteristics such as the 3 minimal MSC criteria, ALLOB® expressed significantly higher levels of chondro/osteoblastic genes such as BMP2 (fold change (FC) > 100), ALPL (FC > 12), CBFA1 (FC > 3) and differentiated significantly earlier than BM-MSC toward the osteogenic lineage. Moreover the bone formation model in nude mice demonstrated that used at the same cellular concentration, ALLOB® was able to induce significantly more (160% vs.107% for control animals) bone formation than BM-MSC (118% vs. 107 % for control animals) two weeks after administration. Conclusion: Our side-by-side comparison studies demonstrated that in vitro and in vivo, ALLOB® displays superior osteogenic capacity to BM-MScs and is therefore a better candidate for the treatment of bone fractures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=gene%20expression" title="gene expression">gene expression</a>, <a href="https://publications.waset.org/abstracts/search?q=histomorphometry" title=" histomorphometry"> histomorphometry</a>, <a href="https://publications.waset.org/abstracts/search?q=mesenchymal%20stem%20cells" title=" mesenchymal stem cells"> mesenchymal stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=osteogenic%20differentiation%20potential" title=" osteogenic differentiation potential"> osteogenic differentiation potential</a>, <a href="https://publications.waset.org/abstracts/search?q=preclinical" title=" preclinical"> preclinical</a> </p> <a href="https://publications.waset.org/abstracts/44433/superiority-of-bone-marrow-derived-osteoblastic-cells-allob-over-bone-marrow-derived-mesenchymal-stem-cells" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44433.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">330</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1319</span> Influence of Ligature Tightening on Bone Fracture Risk in Interspinous Process Surgery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dae%20Kyung%20Choi">Dae Kyung Choi</a>, <a href="https://publications.waset.org/abstracts/search?q=Won%20Man%20Park"> Won Man Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Kyungsoo%20Kim"> Kyungsoo Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Yoon%20Hyuk%20Kim"> Yoon Hyuk Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The interspinous process devices have been recently used due to its advantages such as minimal invasiveness and less subsidence of the implant to the osteoporotic bone. In this paper, we have analyzed the influences of ligature tightening of several interspinous process devices using finite element analysis. Four types of interspinous process implants were inserted to the L3-4 spinal motion segment based on their surgical protocols. Inferior plane of L4 vertebra was fixed and 7.5 Nm of extension moment were applied on superior plane of L3 vertebra with 400N of compressive load along follower load direction and pretension of the ligature. The stability of the spinal unit was high enough than that of intact model. The higher value of pretension in the ligature led the decrease of dynamic stabilization effect in cases of the WallisTM, DiamTM, Viking, and Spear®. The results of present study could be used to evaluate surgical option and validate the biomechanical characteristics of the spinal implants. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=interspinous%20process%20device" title="interspinous process device">interspinous process device</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20fracture%20risk" title=" bone fracture risk"> bone fracture risk</a>, <a href="https://publications.waset.org/abstracts/search?q=lumbar%20spine" title=" lumbar spine"> lumbar spine</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis "> finite element analysis </a> </p> <a href="https://publications.waset.org/abstracts/17346/influence-of-ligature-tightening-on-bone-fracture-risk-in-interspinous-process-surgery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17346.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">400</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1318</span> The Nutrient Foramen of the Scaphoid Bone – A Morphological Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=B.%20V.%20Murlimanju">B. V. Murlimanju</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20J.%20Jiji"> P. J. Jiji</a>, <a href="https://publications.waset.org/abstracts/search?q=Latha%20V.%20Prabhu"> Latha V. Prabhu</a>, <a href="https://publications.waset.org/abstracts/search?q=Mangala%20M.%20Pai"> Mangala M. Pai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The scaphoid is the most commonly fractured bone of the wrist. The fracture may disrupt the vessels and end up as the avascular necrosis of the bone. The objective of the present study was to investigate the morphology and number of the nutrient foramina in the cadaveric dried scaphoid bones of the Indian population. Methods: The present study included 46 scaphoid bones (26 right sided and 20 left sided) which were obtained from the gross anatomy laboratory of our institution. The bones were macroscopically observed for the nutrient foramina and the data was collected with respect to their number. The tabulation of the data and analysis were done. Results: All of our specimens (100%) exhibited the nutrient foramina over the non-articular surfaces. The foramina were observed only over the palmar and dorsal surfaces of the scaphoid bones. The foramina were observed both proximal and distal to the mid waist of the scaphoid bone. The foramen ranged between 9 and 54 in each scaphoid bone. The foramina over the palmar surface ranged between, 2-24 in number. The foramina over the dorsal surface ranged between, 7-36 in number. The foramina proximal to the waist ranged between 2 and 24 in number and distal to the waist ranged between 3 and 39. Conclusion: We believe that the present study has provided additional data about the nutrient foramina of the scaphoid bones. The data is enlightening to the orthopedic surgeon and would help in the hand surgeries. The morphological knowledge of the vasculature, their foramina of entry and their number is required to understand the concepts in the avascular necrosis of the proximal scaphoid and non-union of the fracture at the waist of the scaphoid. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=avascular%20necrosis" title="avascular necrosis">avascular necrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=nutrient" title=" nutrient"> nutrient</a>, <a href="https://publications.waset.org/abstracts/search?q=scaphoid" title=" scaphoid"> scaphoid</a>, <a href="https://publications.waset.org/abstracts/search?q=vascular" title=" vascular"> vascular</a> </p> <a href="https://publications.waset.org/abstracts/27733/the-nutrient-foramen-of-the-scaphoid-bone-a-morphological-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27733.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">343</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1317</span> Bone Mineral Density and Quality, Body Composition of Women in the Postmenopausal Period</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vladyslav%20Povoroznyuk">Vladyslav Povoroznyuk</a>, <a href="https://publications.waset.org/abstracts/search?q=Oksana%20Ivanyk"> Oksana Ivanyk</a>, <a href="https://publications.waset.org/abstracts/search?q=Nataliia%20Dzerovych"> Nataliia Dzerovych</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the diagnostics of osteoporosis, the gold standard is considered to be bone mineral density; however, X-ray densitometry is not an accurate indicator of osteoporotic fracture risk under all circumstances. In this regard, the search for new methods that could determine the indicators not only of the mineral density, but of the bone tissue quality, is a logical step for diagnostic optimization. One of these methods is the evaluation of trabecular bone quality. The aim of this study was to examine the quality and mineral density of spine bone tissue, femoral neck, and body composition of women depending on the duration of the postmenopausal period, to determine the correlation of body fat with indicators of bone mineral density and quality. The study examined 179 women in premenopausal and postmenopausal periods. The patients were divided into the following groups: Women in the premenopausal period and women in the postmenopausal period at various stages (early, middle, late postmenopause). A general examination and study of the above parameters were conducted with General Electric X-ray densitometer. The results show that bone quality and mineral density probably deteriorate with advancing of postmenopausal period. Total fat and lean mass ratio is not likely to change with age. In the middle and late postmenopausal periods, the bone tissue mineral density of the spine and femoral neck increases along with total fat mass. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title="osteoporosis">osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20tissue%20mineral%20density" title=" bone tissue mineral density"> bone tissue mineral density</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20quality" title=" bone quality"> bone quality</a>, <a href="https://publications.waset.org/abstracts/search?q=fat%20mass" title=" fat mass"> fat mass</a>, <a href="https://publications.waset.org/abstracts/search?q=lean%20mass" title=" lean mass"> lean mass</a>, <a href="https://publications.waset.org/abstracts/search?q=postmenopausal%20osteoporosis" title=" postmenopausal osteoporosis"> postmenopausal osteoporosis</a> </p> <a href="https://publications.waset.org/abstracts/66298/bone-mineral-density-and-quality-body-composition-of-women-in-the-postmenopausal-period" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66298.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">343</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1316</span> An Unusual Fracture Pattern: Fracture of the Distal Radius (Colles') along with Fracture of the Ipsilateral Scaphoid & Capitate Bones</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Srikanta%20Tagore%20Sarkar">Srikanta Tagore Sarkar</a>, <a href="https://publications.waset.org/abstracts/search?q=Prasanta%20Kumar%20Mandal"> Prasanta Kumar Mandal</a>, <a href="https://publications.waset.org/abstracts/search?q=Dibakar%20Roy"> Dibakar Roy </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The association of a capitate fracture with a scaphoid fracture has been termed as the naviculocapitate syndrome. The existence of some nondisplaced fractures of scaphoid and capitate with or without the fracture of lunate or radius suggests that there is a spectrum of these injuries, and this confuses the terminology. With our case; we report an unusual variety of this naviculocapitate syndrome with distal radial Colles fracture in addition to the nondisplaced fractures of the scaphoid, capitate and the dorsal lip of radial fracture. When we looked at the literature there is no another Colles fracture reported together with undisplaced scapho-capitate syndrome. The coronal and sagittal images that obtained from the MDCT (Multidetector computed tomography) is useful and effective imaging modality to diagnose complex wrist fractures with more details that are not detected in X-rays. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=scaphoid" title="scaphoid">scaphoid</a>, <a href="https://publications.waset.org/abstracts/search?q=capitate" title=" capitate"> capitate</a>, <a href="https://publications.waset.org/abstracts/search?q=Colles%E2%80%99%20fracture" title=" Colles’ fracture"> Colles’ fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=syndrome" title=" syndrome"> syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=MDCT" title=" MDCT"> MDCT</a>, <a href="https://publications.waset.org/abstracts/search?q=unusual" title=" unusual"> unusual</a> </p> <a href="https://publications.waset.org/abstracts/13989/an-unusual-fracture-pattern-fracture-of-the-distal-radius-colles-along-with-fracture-of-the-ipsilateral-scaphoid-capitate-bones" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13989.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">393</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1315</span> Induced Bone Tissue Temperature in Drilling Procedures: A Comparative Laboratory Study with and without Lubrication</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=L.%20Roseiro">L. Roseiro</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Veiga"> C. Veiga</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Maranha"> V. Maranha</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Neto"> A. Neto</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Laraqi"> N. Laraqi</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ba%C3%AFri"> A. Baïri</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Alilat"> N. Alilat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In orthopedic surgery there are various situations in which the surgeon needs to implement methods of cutting and drilling the bone. With this type of procedure the generated friction leads to a localized increase in temperature, which may lead to the bone necrosis. Recognizing the importance of studying this phenomenon, an experimental evaluation of the temperatures developed during the procedure of drilling bone has been done. Additionally the influence of the use of the procedure with / without additional lubrication during drilling of bone has also been done. The obtained results are presented and discussed and suggests an advantage in using additional lubrication as a way to minimize the appearance of bone tissue necrosis during bone drilling procedures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20necrosis" title="bone necrosis">bone necrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20drilling" title=" bone drilling"> bone drilling</a>, <a href="https://publications.waset.org/abstracts/search?q=thermography" title=" thermography"> thermography</a>, <a href="https://publications.waset.org/abstracts/search?q=surgery" title=" surgery"> surgery</a> </p> <a href="https://publications.waset.org/abstracts/16605/induced-bone-tissue-temperature-in-drilling-procedures-a-comparative-laboratory-study-with-and-without-lubrication" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16605.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">598</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1314</span> FracXpert: Ensemble Machine Learning Approach for Localization and Classification of Bone Fractures in Cricket Athletes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Madushani%20Rodrigo">Madushani Rodrigo</a>, <a href="https://publications.waset.org/abstracts/search?q=Banuka%20Athuraliya"> Banuka Athuraliya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In today's world of medical diagnosis and prediction, machine learning stands out as a strong tool, transforming old ways of caring for health. This study analyzes the use of machine learning in the specialized domain of sports medicine, with a focus on the timely and accurate detection of bone fractures in cricket athletes. Failure to identify bone fractures in real time can result in malunion or non-union conditions. To ensure proper treatment and enhance the bone healing process, accurately identifying fracture locations and types is necessary. When interpreting X-ray images, it relies on the expertise and experience of medical professionals in the identification process. Sometimes, radiographic images are of low quality, leading to potential issues. Therefore, it is necessary to have a proper approach to accurately localize and classify fractures in real time. The research has revealed that the optimal approach needs to address the stated problem and employ appropriate radiographic image processing techniques and object detection algorithms. These algorithms should effectively localize and accurately classify all types of fractures with high precision and in a timely manner. In order to overcome the challenges of misidentifying fractures, a distinct model for fracture localization and classification has been implemented. The research also incorporates radiographic image enhancement and preprocessing techniques to overcome the limitations posed by low-quality images. A classification ensemble model has been implemented using ResNet18 and VGG16. In parallel, a fracture segmentation model has been implemented using the enhanced U-Net architecture. Combining the results of these two implemented models, the FracXpert system can accurately localize exact fracture locations along with fracture types from the available 12 different types of fracture patterns, which include avulsion, comminuted, compressed, dislocation, greenstick, hairline, impacted, intraarticular, longitudinal, oblique, pathological, and spiral. This system will generate a confidence score level indicating the degree of confidence in the predicted result. Using ResNet18 and VGG16 architectures, the implemented fracture segmentation model, based on the U-Net architecture, achieved a high accuracy level of 99.94%, demonstrating its precision in identifying fracture locations. Simultaneously, the classification ensemble model achieved an accuracy of 81.0%, showcasing its ability to categorize various fracture patterns, which is instrumental in the fracture treatment process. In conclusion, FracXpert has become a promising ML application in sports medicine, demonstrating its potential to revolutionize fracture detection processes. By leveraging the power of ML algorithms, this study contributes to the advancement of diagnostic capabilities in cricket athlete healthcare, ensuring timely and accurate identification of bone fractures for the best treatment outcomes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=multiclass%20classification" title="multiclass classification">multiclass classification</a>, <a href="https://publications.waset.org/abstracts/search?q=object%20detection" title=" object detection"> object detection</a>, <a href="https://publications.waset.org/abstracts/search?q=ResNet18" title=" ResNet18"> ResNet18</a>, <a href="https://publications.waset.org/abstracts/search?q=U-Net" title=" U-Net"> U-Net</a>, <a href="https://publications.waset.org/abstracts/search?q=VGG16" title=" VGG16"> VGG16</a> </p> <a href="https://publications.waset.org/abstracts/184317/fracxpert-ensemble-machine-learning-approach-for-localization-and-classification-of-bone-fractures-in-cricket-athletes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184317.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">120</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1313</span> Micro-CT Assessment of Fracture Healing in Androgen-Deficient Osteoporosis Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20N.%20Shuid">Ahmad N. Shuid</a>, <a href="https://publications.waset.org/abstracts/search?q=Azri%20Jalil"> Azri Jalil</a>, <a href="https://publications.waset.org/abstracts/search?q=Sabarul%20A.%20Mokhtar"> Sabarul A. Mokhtar</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohd%20F.%20Khamis"> Mohd F. Khamis</a>, <a href="https://publications.waset.org/abstracts/search?q=Norliza%20Muhammad"> Norliza Muhammad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Micro-CT provides a 3-D image of fracture callus, which can be used to calculate quantitative parameters. In this study, micro-CT was used to assess the fracture healing of orchidectomised rats, an androgen-deficient osteoporosis model. The effect of testosterone (hormone replacement) on fracture healing was also assessed with micro-CT. The rats were grouped into orchidectomised-control (ORX), sham-operated (SHAM), and orchidectomised; and injected with testosterone intramuscularly once weekly (TEN). Treatment duration was six weeks. The fracture was induced and fixed with plates and screws in the right tibia of all the rats. An in vitro micro-CT was used to scan the fracture callus area which consisted of 100 axial slices above and below fracture line. The analysis has shown that micro-CT was able to detect a significant difference in the fracture healing rate of ORX and TEN groups. In conclusion, micro-CT can be used to assess fracture healing in androgen-deficient osteoporosis. This imaging tool can be used to test agents that influence fracture healing in the androgen-deficient model. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=androgen" title="androgen">androgen</a>, <a href="https://publications.waset.org/abstracts/search?q=fracture" title=" fracture"> fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=orchidectomy" title=" orchidectomy"> orchidectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis "> osteoporosis </a> </p> <a href="https://publications.waset.org/abstracts/33626/micro-ct-assessment-of-fracture-healing-in-androgen-deficient-osteoporosis-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33626.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">545</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1312</span> Suitability Evaluation of CNW as Scaffold for Osteoblast</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hoo%20Cheol%20Lee">Hoo Cheol Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Dae%20Seung%20Kim"> Dae Seung Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Sang%20Myung%20Jung"> Sang Myung Jung</a>, <a href="https://publications.waset.org/abstracts/search?q=Gwang%20Heum%20Yoon"> Gwang Heum Yoon</a>, <a href="https://publications.waset.org/abstracts/search?q=Hwa%20Sung%20Shin"> Hwa Sung Shin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Loss of bone tissue can occur due to a bone tissue disease and aging or fracture. Renewable formation of bone is mainly made by its differentiation and metabolism. For this reason, osteoblasts have been studied for regeneration of bone tissue. So, tissue engineering has attracted attention as a recovery means. In tissue engineering, a particularly important factor is a scaffold that supports cell growth. For osteoblast scaffold, we used the cellulose nanowhisker (CNW) extracted from marine organism. CNW is one of an abundant material obtained from a number of plants and animals. CNW is polymer consisting of monomer cellulose and this composition offers biodegradability and biocompatibility to CNW. Mechanical strength of CNW is superior to the existing natural polymers. In addition, substances of marine origin have a low risk of secondary infection by bacteria and pathogen in contrast with those of land-derived. For evaluating its suitability as an osteoblast scaffold, we fabricate CNW film for osteoblast culture and performed the MTT assay and ALP assay to confirm its cytotoxicity and effect on differentiation. Taking together these results, we assessed CNW is a potential candidate of a material for bone tissue regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20regeneration" title="bone regeneration">bone regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=cellulose%20nanowhisker" title=" cellulose nanowhisker"> cellulose nanowhisker</a>, <a href="https://publications.waset.org/abstracts/search?q=marine%20derived%20material" title=" marine derived material"> marine derived material</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoblast" title=" osteoblast"> osteoblast</a> </p> <a href="https://publications.waset.org/abstracts/7802/suitability-evaluation-of-cnw-as-scaffold-for-osteoblast" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7802.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">347</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1311</span> Epidemiology and Risk Factors of Injury and Stress Fractures in Male and Female Runners</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Balazs%20Patczai">Balazs Patczai</a>, <a href="https://publications.waset.org/abstracts/search?q=Katalin%20Gocze"> Katalin Gocze</a>, <a href="https://publications.waset.org/abstracts/search?q=Gabriella%20Kiss"> Gabriella Kiss</a>, <a href="https://publications.waset.org/abstracts/search?q=Dorottya%20%20Szabo"> Dorottya Szabo</a>, <a href="https://publications.waset.org/abstracts/search?q=Tibor%20Mintal"> Tibor Mintal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Running has become increasingly popular on a global scale in the past decades. Amateur athletes are taking their sport to a new level in an attempt to surpass their performance goals. The aim of our study was to assess the musculoskeletal condition of amateur runners and the prevalence of injuries with a special focus on stress fracture risk. Methods: The cross sectional analysis included ankle mobility, hamstring and lower back flexibility, the use of Renne’s test for iliotibial band syndrome, functional tests for trunk and rotary stability, and measurements of bone density. Data was collected at 2 major half-marathon events in Hungary. Results: Participants (n=134) mean age was 41.76±8.57 years (males: 40.67±8.83, females: 42.08±8.56). Measures of hamstring and lower back flexibility fell into the category of good for both genders (males: 7.13±6.83cm, females: 10.17±6.67cm). No side asymmetry nor gender differences were characteristic in the case of ankle mobility. Trunk stability was significantly better for males than in females (p=0.004). Markers of bone health were in the low normal range for females and were significantly better for males (T-score: p=0.003, T-ratio: p=0.014, Z-score: p=0.034, Z-ratio: p=0.011). 5.2% of females had a previous stress fracture and 24.1% experienced irregular menstrual cycles during the past year. As for the knowledge on the possible association of energy deficiency, menstrual disturbances and their effect on bone health, Only 8.6% of females have heard of the female athlete triad either during their studies or from a health professional. Discussion: The overall musculoskeletal state was satisfactory for both genders both physically and functionally. More attention and effort should be placed on primary and secondary prevention of amateur runners. Very few active women are well informed about the effects of low energy availability and menstrual dysfunction and the negative impact these have on bone health. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20health" title="bone health">bone health</a>, <a href="https://publications.waset.org/abstracts/search?q=flexibility" title=" flexibility"> flexibility</a>, <a href="https://publications.waset.org/abstracts/search?q=running" title=" running"> running</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20fracture" title=" stress fracture"> stress fracture</a> </p> <a href="https://publications.waset.org/abstracts/121546/epidemiology-and-risk-factors-of-injury-and-stress-fractures-in-male-and-female-runners" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/121546.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">125</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1310</span> Evaluation of Compressive Mechanical Properties of the Radial Bone Defect Treated with Selected Bone Graft Substitute Materials in Rabbit</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Omid%20Gholipoor%20Bashiri">Omid Gholipoor Bashiri</a>, <a href="https://publications.waset.org/abstracts/search?q=Ghafur%20Mosavi"> Ghafur Mosavi</a>, <a href="https://publications.waset.org/abstracts/search?q=Aliasghar%20Behnamghader"> Aliasghar Behnamghader</a>, <a href="https://publications.waset.org/abstracts/search?q=Seyed%20Mahmood%20Rabiee"> Seyed Mahmood Rabiee</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To determine the effect of selected bone graft on the compression properties of radial bone in rabbit. Design-Experimental in vivo study. Animals: A total of 45 adult male New Zealand white rabbits. Procedures: The rabbits were anesthetized and a one-cm-full thickness piece of radial bone was removed using oscillating saw in the all rabbit. The rabbits were divided into 5 groups on the basis of the material used to fill the bone defect: group 1: the paste of bone cement calcium phosphate; group II: the paste of calcium phosphate mixture with type I collagen; group III: tricalcium phosphate mixed with hydroxyapatite (TCP & HP) with 5% porosity; group IV: the same scaffold as group III with 10% porosity; and group V: the same scaffold as group III and IV with 20% porosity, with 9 rabbits in each group. Subsequently subdivided into 3 subgroups of 3 rabbits each. Results: There was a significant increase in compression properties of radial bone in the group II and V in 2nd and 3rd months as compared with groups I, III and IV. The mean endurable crack-strength in group II and V were slightly higher than that of normal radius (P<0.05). Conclusion and clinical relevance: Application of calcium phosphate paste with type I collagen and scaffold of tricalcium phosphate with hydroxyapatite having 20% porosity indicated to have positive effect in integral formation of qualitative callus at the site of fracture and early re-organization of callus to regain mechanical strength too. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calcium%20phosphate" title="calcium phosphate">calcium phosphate</a>, <a href="https://publications.waset.org/abstracts/search?q=tricalcium%20phosphate" title=" tricalcium phosphate"> tricalcium phosphate</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=radial%20bone" title=" radial bone"> radial bone</a>, <a href="https://publications.waset.org/abstracts/search?q=compressive%20properties" title=" compressive properties"> compressive properties</a>, <a href="https://publications.waset.org/abstracts/search?q=porosity" title=" porosity"> porosity</a>, <a href="https://publications.waset.org/abstracts/search?q=type%20i%20collagen" title=" type i collagen"> type i collagen</a>, <a href="https://publications.waset.org/abstracts/search?q=rabbit" title=" rabbit"> rabbit</a> </p> <a href="https://publications.waset.org/abstracts/9365/evaluation-of-compressive-mechanical-properties-of-the-radial-bone-defect-treated-with-selected-bone-graft-substitute-materials-in-rabbit" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9365.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">452</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1309</span> Change of Bone Density with Treatments of Intravenous Zoledronic Acid in Patients with Osteoporotic Distal Radial Fractures</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hong%20Je%20Kang">Hong Je Kang</a>, <a href="https://publications.waset.org/abstracts/search?q=Young%20Chae%20Choi"> Young Chae Choi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jin%20Sung%20Park"> Jin Sung Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Isac%20Kim"> Isac Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: Osteoporotic fractures are an important among postmenopausal women. When osteoporotic distal radial fractures occur, osteoporosis must be treated to prevent the hip and spine fractures. Intravenous injection of Zoledronic acid is expected to improve preventing osteoporotic fractures. Many articles reported the effect of intravenous Zoledronic acid to BMD of the hip and spine fracture or non-fracture patients with low BMD. However, that with distal radial fractures has rarely been reported. Therefore, the authors decided to study the effect of Zoledronic acid in BMD score, bone union, and bone turnover markers in the patients who underwent volar plating due to osteoporotic distal radial fractures. Materials: From April 2018 to May 2022, postmenopausal women aged 55 years or older who had osteoporotic distal radial fractures and who underwent surgical treatment using volar plate fixation were included. Zoledronic acid (5mg) was injected intravenously between 3 and 5 days after surgery. BMD scores after 1 year of operation were compared with the initial scores. Bone turnover markers were measured before surgery, after 3 months, and after 1 year. Radiological follow-up was performed every 2 weeks until the bone union and at 1 year postoperatively. Clinical outcome indicators were measured one year after surgery, and the occurrence of side effects was observed. Result: Total of 23 patients were included, with a lumbar BMD T score of -2.89±0.2 before surgery to -2.27±0.3 one year after surgery (p=0.012) and a femoral neck BMD T score of -2.45±0.3 before surgery to -2.36±0.3 (p=0.041) after one year, and all were statistically significant. Measured as bone resorption markers, serum CTX-1 was 337.43±10.4 pg/mL before surgery, 160.86±8.7 pg/mL (p=0.022) after three months, and 250.12±12.7 pg/mL (p=0.031) after one year. Urinary NTX-1 was 39.24±2.2 ng/mL before surgery, 24.46±1.2 ng/mL (p=0.014) after three months and 30.35±1.6 ng/mL (p=0.042) after one year. Measured as bone formation markers, serum osteocalcin was 13.04±1.1 ng/mL before surgery, 8.84±0.7 ng/mL (p=0.037) after 3 months and 11.1±0.4 ng/mL (p=0.026) after one year. Serum bone-specific ALP was 11.24±0.9 IU/L before surgery, 8.25±0.9 IU/L (p=0.036) after three months, and 10.2±0.9 IU/L (p=0.027) after one year. All were statistically significant. All cases showed bone union within an average of 6.91±0.3 weeks without any signs of failure. Complications were found in 5 out of 23 cases (21.7%), such as headache, nausea, muscle pain, and fever. Conclusion: When Zoledronic acid was used, BMD was improved in both the spine and femoral neck. This may reduce the likelihood and subsequent morbidity of additional osteoporotic fractures. This study is meaningful in that there was no difference in the duration of bone union and radiological characteristics in patients with distal radial fractures administrated with intravenous BP early after the fractures, and improvement in BMD and bone turnover indicators was measured. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=zeoldreonic%20acid" title="zeoldreonic acid">zeoldreonic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=BMD" title=" BMD"> BMD</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis"> osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=distal%20radius" title=" distal radius"> distal radius</a> </p> <a href="https://publications.waset.org/abstracts/152035/change-of-bone-density-with-treatments-of-intravenous-zoledronic-acid-in-patients-with-osteoporotic-distal-radial-fractures" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152035.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">115</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1308</span> The Effect of Surface Modified Nano-Hydroxyapatite Incorporation into Polymethylmethacrylate Cement on Biocompatibility and Mechanical Properties</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yu-Shan%20Wu">Yu-Shan Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=Po-Liang%20Lai"> Po-Liang Lai</a>, <a href="https://publications.waset.org/abstracts/search?q=I-Ming%20Chu"> I-Ming Chu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Poly(methylmethacrylate)(PMMA) is the most frequently used bone void filler for vertebral augmentation in osteoporotic fracture. PMMA bone cement not only exhibits strong mechanical properties but also can fabricate according to the shape of bone defect. However, the adhesion between the PMMA-based cement and the adjacent bone is usually weak and as PMMA bone cement is inherently bioinert. The combination of bioceramics and polymers as composites may increase cell adhesion and improve biocompatibility. The nano-hydroxyapatite(HAP) not only plays a significant role in maintaining the properties of the natural bone but also offers a favorable environment for osteoconduction, protein adhesion, and osteoblast proliferation. However, defects and cracks can form at the polymer/ceramics interface, resulting in uneven distribution of stress and subsequent inferior mechanical strength. Surface-modified HAP nano-crystals were prepared by chemically grafting poly(ε-caprolactone)(PCL) on surface-modified nano-HAP surface to increase the affinity of polymer/ceramic phases .Thus, incorporation of surface-modified nano-hydroxyapatite (EC-HAP) may not only improve the interfacial adhesion between cement and bone and between nanoparticles and cement, but also increase biocompatibility. In this research, PMMA mixing with 0, 5, 10, 15, 20, 25 and 30 wt% EC-HAP were examined. MC3T3-E1 cells were used for the biological evaluation of the response to the cements in vitro. Morphology was observed using scanning electron microscopy (SEM). Mechanical properties of HAP/PMMA and EC-HAP/PMMA cement were investigated by compression test. Surface wettability of the cements was measured by contact angles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20cement" title="bone cement">bone cement</a>, <a href="https://publications.waset.org/abstracts/search?q=biocompatibility" title=" biocompatibility"> biocompatibility</a>, <a href="https://publications.waset.org/abstracts/search?q=nano-hydroxyapatite" title=" nano-hydroxyapatite"> nano-hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=polycaprolactone" title=" polycaprolactone"> polycaprolactone</a>, <a href="https://publications.waset.org/abstracts/search?q=PMMA" title=" PMMA"> PMMA</a>, <a href="https://publications.waset.org/abstracts/search?q=surface%20grafting" title=" surface grafting"> surface grafting</a> </p> <a href="https://publications.waset.org/abstracts/45200/the-effect-of-surface-modified-nano-hydroxyapatite-incorporation-into-polymethylmethacrylate-cement-on-biocompatibility-and-mechanical-properties" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45200.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">395</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1307</span> Fabrication of Cheap Novel 3d Porous Scaffolds Activated by Nano-Particles and Active Molecules for Bone Regeneration and Drug Delivery Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mostafa%20Mabrouk">Mostafa Mabrouk</a>, <a href="https://publications.waset.org/abstracts/search?q=Basma%20E.%20Abdel-Ghany"> Basma E. Abdel-Ghany</a>, <a href="https://publications.waset.org/abstracts/search?q=Mona%20Moaness"> Mona Moaness</a>, <a href="https://publications.waset.org/abstracts/search?q=Bothaina%20M.%20Abdel-Hady"> Bothaina M. Abdel-Hady</a>, <a href="https://publications.waset.org/abstracts/search?q=Hanan%20H.%20Beherei"> Hanan H. Beherei</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Tissue engineering became a promising field for bone repair and regenerative medicine in which cultured cells, scaffolds and osteogenic inductive signals are used to regenerate tissues. The annual cost of treating bone defects in Egypt has been estimated to be many billions, while enormous costs are spent on imported bone grafts for bone injuries, tumors, and other pathologies associated with defective fracture healing. The current study is aimed at developing a more strategic approach in order to speed-up recovery after bone damage. This will reduce the risk of fatal surgical complications and improve the quality of life of people affected with such fractures. 3D scaffolds loaded with cheap nano-particles that possess an osteogenic effect were prepared by nano-electrospinning. The Microstructure and morphology characterizations of the 3D scaffolds were monitored using scanning electron microscopy (SEM). The physicochemical characterization was investigated using X-ray diffractometry (XRD) and infrared spectroscopy (IR). The Physicomechanical properties of the 3D scaffold were determined by a universal testing machine. The in vitro bioactivity of the 3D scaffold was assessed in simulated body fluid (SBF). The bone-bonding ability of novel 3D scaffolds was also evaluated. The obtained nanofibrous scaffolds demonstrated promising microstructure, physicochemical and physicomechanical features appropriate for enhanced bone regeneration. Therefore, the utilized nanomaterials loaded with the drug are greatly recommended as cheap alternatives to growth factors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20regeneration" title="bone regeneration">bone regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=cheap%20scaffolds" title=" cheap scaffolds"> cheap scaffolds</a>, <a href="https://publications.waset.org/abstracts/search?q=nanomaterials" title=" nanomaterials"> nanomaterials</a>, <a href="https://publications.waset.org/abstracts/search?q=active%20molecules" title=" active molecules"> active molecules</a> </p> <a href="https://publications.waset.org/abstracts/146968/fabrication-of-cheap-novel-3d-porous-scaffolds-activated-by-nano-particles-and-active-molecules-for-bone-regeneration-and-drug-delivery-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/146968.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">188</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20fracture&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20fracture&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20fracture&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=bone%20fracture&page=5">5</a></li> <li class="page-item"><a class="page-link" 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