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stenosis</title> <meta name="description" content="Search results for: vaginal stenosis"> <meta name="keywords" content="vaginal stenosis"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="vaginal stenosis"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 188</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: vaginal stenosis</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">188</span> A Retrospective Study of Vaginal Stenosis Following Treatment of Cervical Cancers and the Effectiveness of Rehabilitation Interventions</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manjusha%20R.%20Vagal">Manjusha R. Vagal</a>, <a href="https://publications.waset.org/abstracts/search?q=Shyam%20K.%20Shrivastava"> Shyam K. Shrivastava</a>, <a href="https://publications.waset.org/abstracts/search?q=Umesh%20Mahantshetty"> Umesh Mahantshetty</a>, <a href="https://publications.waset.org/abstracts/search?q=Sudeep%20Gupta"> Sudeep Gupta</a>, <a href="https://publications.waset.org/abstracts/search?q=Supriya%20Chopra"> Supriya Chopra</a>, <a href="https://publications.waset.org/abstracts/search?q=Reena%20Engineer"> Reena Engineer</a>, <a href="https://publications.waset.org/abstracts/search?q=Amita%20Maheshwari"> Amita Maheshwari</a>, <a href="https://publications.waset.org/abstracts/search?q=Atul%20Buduk"> Atul Buduk</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Vaginal stenosis is a common side effect associated with pelvic radiotherapy in cervical cancer patients which contributes negatively to woman’s health and prevents adequate vaginal/cervical examination. Vaginal dilation with a dilator is routine practice and is internationally advocated as a prophylactic measure to preserve vaginal patency. This retrospective study was carried out with the aim to know the usefulness of vaginal dilation following pelvic radiation therapy in cervical cancer patients in India. Data from medical records of 183 cervical cancer patients, which met the study criteria, were collected related to the stage of the disease, treatment received, commencement period of dilation post radiation therapy, sexual status and side effects associated to dilation practice. Data related to vaginal dimensions as per the length of insertion of a small, medium and large dilator were collected on regular follow-ups until 36 months and/or more. Vaginal dimensions as measured with the length of medium dilator insertion were used for analysis of dilation therapy results using paired t-test. Patients who underwent vaginal dilation with dilator maintained vaginal patency, also the mean vaginal length significantly increased, from 8.02 cm ± 2.69 to 9.96 ± 2.89 cm with a p value <0.001. There was no significant difference found on vaginal patency with different intervals of initiation of dilation therapy. At the third year and more following dilation therapy, significant increase in vaginal length observed with a p value of 0.0001 in both sexually active and inactive patients. Compilation of vaginal dosage during brachytherapy was inadequate, and hence, the secondary objective of the study to determine the effect of radiotherapy on the outcome of rehabilitation intervention was not studied in detail. This retrospective study has found that dilation therapy with vaginal dilators post pelvic radiotherapy is effective in preventing vaginal stenosis and improving vaginal patency and cannot be substituted with vaginal intercourse. Sexual quality of life assessment in the Indian population needs much attention. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dilator" title="dilator">dilator</a>, <a href="https://publications.waset.org/abstracts/search?q=sexually%20active" title=" sexually active"> sexually active</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20dilation" title=" vaginal dilation"> vaginal dilation</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20stenosis" title=" vaginal stenosis"> vaginal stenosis</a> </p> <a href="https://publications.waset.org/abstracts/58707/a-retrospective-study-of-vaginal-stenosis-following-treatment-of-cervical-cancers-and-the-effectiveness-of-rehabilitation-interventions" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58707.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">201</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">187</span> Anal Repair and Diamond Flap in Moderate Anal Stenosis Patient After an Open Hemorrhoidectomy Surgery: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Andriana%20Purnama">Andriana Purnama</a>, <a href="https://publications.waset.org/abstracts/search?q=Reno%20Rudiman"> Reno Rudiman</a>, <a href="https://publications.waset.org/abstracts/search?q=Kezia%20Christy"> Kezia Christy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Anal stenosis which develops due to anoderm scarring usually caused by secondary to surgical trauma, has become common, causing significant decrease patient’s quality of life. Even though mild anal stenosis was treated with non-surgical treatment, but surgical reconstruction in unavoidable for moderate to severe anal stenosis that cause distressing, severe anal pain and inability to defecate. In our study, we intend to share our result with the use of diamond flap in treatment of anal stenosis. This case report illustrates a 57-year-old male patient who presented with difficulty and discomfort in defecation caused by anal stenosis after 2 years of open hemorrhoidectomy surgery. At physical examination, there was requirement of forceful dilatation when the index finger was inserted or precisely 6mm as measured by hegar dilator (moderate anal stenosis). Blood test result was within normal limits. The patient underwent anal repair and diamond flap where the scar tissue at 6 and 9 o’clock directions was excised and diamond graft was incised carefully while paying attention to the vascular supply. Finally, the graft was fixated without any tension to the anal canal, resulting in diameter of 2 cm after operation. After 2 days post operation, the patient was in stable condition, without any complication, and discharged. There was no abnormality concerning the stool. Ten days after the operation, diamond flap was in normal condition and without any complication. He was scheduled for futher follow up at the Digestive Surgery Department. Anal stenosis due to overzealous hemorrhoidectomy is a complication that is preventable when performed in experienced hands. Diamond flap was one of the options for the anal stenosis treatment with less complication. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anal%20stenosis" title="anal stenosis">anal stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=diamond%20flap" title=" diamond flap"> diamond flap</a>, <a href="https://publications.waset.org/abstracts/search?q=post%20hemorrhoidectomy" title=" post hemorrhoidectomy"> post hemorrhoidectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=anal%20repair" title=" anal repair"> anal repair</a> </p> <a href="https://publications.waset.org/abstracts/159843/anal-repair-and-diamond-flap-in-moderate-anal-stenosis-patient-after-an-open-hemorrhoidectomy-surgery-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/159843.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">92</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">186</span> Daye™ Tampon as a Tool for Vaginal Sample Collection Towards the Detection of Genital Infections</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Valentina%20Milanova">Valentina Milanova</a>, <a href="https://publications.waset.org/abstracts/search?q=Kalina%20Mihaylova"> Kalina Mihaylova</a>, <a href="https://publications.waset.org/abstracts/search?q=Iva%20Lazarova"> Iva Lazarova</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The mechanisms by which female genital infections are detected are varied and include clinician-collected high vaginal swabs, clinician-collected endocervical swabs, patient-collected vaginal swabs, and first-pass urine samples. Vaginal health screening has chronically low rates of uptake. This highlights the unmet need for a screening tool with comparable diagnostic accuracy which is familiar, convenient and easy to use for people. The Daye™ medical grade tampon offers an alternative to traditional sampling methods with the potential of increasing screening uptake among people previously too embarrassed or busy to attend gynecological appointments. In this white paper, the results of stability studies and a comparative clinical trial are discussed to assess the suitability of the device for the collection of vaginal samples for various clinical assessments. The tampon has demonstrated good sample stability and comparable sample quality compared to a self-collected vaginal swab and a clinician-collected cervical swab. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vaginal%20microbiome" title="vaginal microbiome">vaginal microbiome</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20infections" title=" vaginal infections"> vaginal infections</a>, <a href="https://publications.waset.org/abstracts/search?q=gynaecological%20infections" title=" gynaecological infections"> gynaecological infections</a>, <a href="https://publications.waset.org/abstracts/search?q=female%20health" title=" female health"> female health</a>, <a href="https://publications.waset.org/abstracts/search?q=menstrual%20tampons" title=" menstrual tampons"> menstrual tampons</a>, <a href="https://publications.waset.org/abstracts/search?q=in%20vitro%20diagnostics" title=" in vitro diagnostics"> in vitro diagnostics</a> </p> <a href="https://publications.waset.org/abstracts/161985/daye-tampon-as-a-tool-for-vaginal-sample-collection-towards-the-detection-of-genital-infections" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161985.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">103</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">185</span> Correction of Urinary Incontinence in Severe Spinal Canal Stenosis, Treated Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ilirian%20La%C3%A7i">Ilirian Laçi</a>, <a href="https://publications.waset.org/abstracts/search?q=Alketa%20Spahiu"> Alketa Spahiu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ageing causes an increase in the number of patients with spinal canal stenosis. Most of the patients have back pain, leg pain, numbness of the legs, as well as urinary incontinence as a very common symptoms. Urinary incontinence impairs the quality of life. Correction of the symptom of urinary incontinence is possible in the early and adequate treatment of spinal stenosis. Methods: This study observed patients with urinary incontinence and spinal canal stenosis. These patients underwent mechanical decompression of the spinal stenosis through surgery. At the same time, these patients were observed clinically with clinical consultations. Cystoscopy and urodynamic tests were conducted at intervals of 2 and 6 months. As a result of treatment, 60% of patients did recover. The patients in this group who benefit from treatment were the patients who were early diagnosed and treated. Conclusions: An important factor in the prognosis of this pathology is the early diagnosis and treatment. The proper treatment of this pathology makes it curable in most cases. An important role in this pathology is played by the neurosurgeon. Surgery accompanied by laminotomy and mechanical decompression is the best way of treatment. Other factors that played a role in this pathology are also a large number of childbirths for women, obesity, etc. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urinary%20incontinence" title="urinary incontinence">urinary incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20of%20life" title=" quality of life"> quality of life</a>, <a href="https://publications.waset.org/abstracts/search?q=spinal%20canal%20stenosis" title=" spinal canal stenosis"> spinal canal stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=early%20diagnosis" title=" early diagnosis"> early diagnosis</a>, <a href="https://publications.waset.org/abstracts/search?q=treatment" title=" treatment"> treatment</a> </p> <a href="https://publications.waset.org/abstracts/152503/correction-of-urinary-incontinence-in-severe-spinal-canal-stenosis-treated-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152503.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">99</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">184</span> Simulation to Detect Virtual Fractional Flow Reserve in Coronary Artery Idealized Models</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nabila%20Jaman">Nabila Jaman</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20E.%20Hoque"> K. E. Hoque</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Sawall"> S. Sawall</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Ferdows"> M. Ferdows </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Coronary artery disease (CAD) is one of the most lethal diseases of the cardiovascular diseases. Coronary arteries stenosis and bifurcation angles closely interact for myocardial infarction. We want to use computer-aided design model coupled with computational hemodynamics (CHD) simulation for detecting several types of coronary artery stenosis with different locations in an idealized model for identifying virtual fractional flow reserve (vFFR). The vFFR provides us the information about the severity of stenosis in the computational models. Another goal is that we want to imitate patient-specific computed tomography coronary artery angiography model for constructing our idealized models with different left anterior descending (LAD) and left circumflex (LCx) bifurcation angles. Further, we want to analyze whether the bifurcation angles has an impact on the creation of narrowness in coronary arteries or not. The numerical simulation provides the CHD parameters such as wall shear stress (WSS), velocity magnitude and pressure gradient (PGD) that allow us the information of stenosis condition in the computational domain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CAD" title="CAD">CAD</a>, <a href="https://publications.waset.org/abstracts/search?q=CHD" title=" CHD"> CHD</a>, <a href="https://publications.waset.org/abstracts/search?q=vFFR" title=" vFFR"> vFFR</a>, <a href="https://publications.waset.org/abstracts/search?q=bifurcation%20angles" title=" bifurcation angles"> bifurcation angles</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20stenosis" title=" coronary stenosis"> coronary stenosis</a> </p> <a href="https://publications.waset.org/abstracts/85911/simulation-to-detect-virtual-fractional-flow-reserve-in-coronary-artery-idealized-models" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85911.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">157</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">183</span> The Interventional, Prospective, Real-World Post-Marketing Clinical Follow-Up Trial of a Polycarbophil Vaginal Moisturising Gel in Women Affected by Vaginal Dryness in Late Menopausal Transition and Postmenopause: A Triple Investigation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Cagnacci">A. Cagnacci</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20F.%20Barattini"> D. F. Barattini</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Casolati"> E. Casolati</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Mangrella"> M. Mangrella</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Piccolo"> E. Piccolo</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Rosu"> S. Rosu</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20C.%20P%C4%83tra%C8%99cu"> L. C. Pătrașcu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This Triple study aimed to evaluate the efficacy of polycarbophil vaginal gel (PCV) in treating symptoms of vaginal atrophy (VA) in peri- and post-menopausal women. Women in peri- (n=29) and postmenopause (n=54) diagnosed with VA were progressively enrolled and treated once a day for 30 days. Thereafter, those wishing to continue (n=73) received the PCV treatment for an additional 180 days. The vaginal health index (VHI) and vaginal dryness, irritation, and pain at intercourse, along with treatment safety, were evaluated at baseline, 30 days of treatment, and after additional 180 days. At baseline, the VHI (p<0.056) and VAS of vaginal dryness (p=0.0001,) irritation (p=0.002), and pain at intercourse (p=0.0001) were worse in postmenopausal women than in perimenopausal women. VHI and VA symptoms improved in all women, and after 30 days of PCV administration, they were similar between peri-and postmenopausal women. After an additional 180 days of treatment, VHI further increased (p=0.0001), VAS of all symptoms (P=0.0001) and the Global Symptom Score (P=0.0001) further decreased. The treatment was safe. Treatment with PCV improves VA symptoms in both peri- and post-menopausal women. Prolongation of treatment up to 6 months increases the efficacy of treatment with no side effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=late%20menopausal%20transition" title="late menopausal transition">late menopausal transition</a>, <a href="https://publications.waset.org/abstracts/search?q=postmenopause" title=" postmenopause"> postmenopause</a>, <a href="https://publications.waset.org/abstracts/search?q=polycarbophil" title=" polycarbophil"> polycarbophil</a>, <a href="https://publications.waset.org/abstracts/search?q=sexuality" title=" sexuality"> sexuality</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20dryness" title=" vaginal dryness"> vaginal dryness</a> </p> <a href="https://publications.waset.org/abstracts/173565/the-interventional-prospective-real-world-post-marketing-clinical-follow-up-trial-of-a-polycarbophil-vaginal-moisturising-gel-in-women-affected-by-vaginal-dryness-in-late-menopausal-transition-and-postmenopause-a-triple-investigation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173565.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">55</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">182</span> Preparation and Optimization of Curcumin-HPβCD Complex Bioadhesive Vaginal Films for Vaginal Candidiasis by Factorial Design</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Umme%20Hani">Umme Hani</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20G.%20Shivakumar"> H. G. Shivakumar</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20D.%20Younus%20Pasha"> M. D. Younus Pasha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of this work was to design and optimize a novel vaginal drug delivery system for more effective treatment against vaginal candidiasis. To achieve a better therapeutic efficacy and patient compliance in the treatment for vaginal candidiasis, herbal antifungal agent Curcumin which is 2.5 fold more potent than fluconazole at inhibiting the adhesion of candida albicans has been formulated in a bio-adhesive vaginal film. Curcumin was formulated in bio-adhesive film formulations that could be retained in the vagina for prolonged intervals. The polymeric films were prepared by solvent evaporation and optimized for various physicodynamic and aesthetic properties. Curcumin HPβCD (Hydroxypropyl β Cyclodextrin) was first developed to increase the solubility of curcumin. The formation of the Curcumin HPβCD complex was characterized by scanning electron microscopy (SEM), differential scanning calorimetry (DSC), and FT-IR and evaluated for its solubility. Curcumin HPβCD complex was formulated in a bio-adhesive film using hydroxypropyl methyl cellulose (HPMC) and Carbopol 934P and characterized. DSC and FT-IR data of Curcumin HPβCD indicate there was complex formation between the drug and HPβCD. The little moisture content (8.02±0.34% w/w) was present in the film, which helps them to remain stable and kept them from being completely dry and brittle. The mechanical properties, tensile strength, and percentage elongation at break reveal that the formulations were found to be soft and tough. The films showed good peelability, relatively good swelling index, and moderate tensile strength and retained vaginal mucosa up to 8 h. The developed Curcumin vaginal film could be a promising safe herbal medication and can ensure longer residence at the vagina and provide an efficient therapy for vaginal candidiasis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=curcumin" title="curcumin">curcumin</a>, <a href="https://publications.waset.org/abstracts/search?q=curcumin-HP%CE%B2CD%20complex" title=" curcumin-HPβCD complex"> curcumin-HPβCD complex</a>, <a href="https://publications.waset.org/abstracts/search?q=bio-adhesive%20vaginal%20film" title=" bio-adhesive vaginal film"> bio-adhesive vaginal film</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20candidiasis" title=" vaginal candidiasis"> vaginal candidiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=23%20factorial%20design" title=" 23 factorial design"> 23 factorial design</a> </p> <a href="https://publications.waset.org/abstracts/11543/preparation-and-optimization-of-curcumin-hpvcd-complex-bioadhesive-vaginal-films-for-vaginal-candidiasis-by-factorial-design" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11543.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">382</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">181</span> Expression of uPA, tPA, and PAI-1 in Calcified Aortic Valves</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abdullah%20M.%20Alzahrani">Abdullah M. Alzahrani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Our physiopathological assumption is that u-PA, t-PA, and PAI-1 are released by calcified aortic valves and play a role in the calcification of these valves. Sixty-five calcified aortic valves were collected from patients suffering from aortic stenosis. Each valve was incubated for 24 hours in culture medium. The supernatants were used to measure u-PA, t-PA, and PAI-1 concentrations; the valve calcification was evaluated using biphotonic absorptiometry. Aortic stenosis valves expressed normal plasminogen activators concentrations and overexpressed PAI-1 (u-PA, t-PA, and PAI-1 mean concentrations were, resp., 1.69 ng/mL ± 0.80, 2.76 ng/mL ± 1.33, and 53.27 ng/mL ± 36.39). There was no correlation between u-PA and PAI-1 (r = 0.3) but t-PA and PAI-1 were strongly correlated with each other (r = 0.6). Over expression of PAI-1 was proportional to the calcium content of theAS valves. Our results demonstrate a consistent increase of PAI-1 proportional to the calcification. The over expression of PAI-1 may be useful as a predictive indicator in patients with aortic stenosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aortic%20valve" title="aortic valve">aortic valve</a>, <a href="https://publications.waset.org/abstracts/search?q=PAI-1" title=" PAI-1"> PAI-1</a>, <a href="https://publications.waset.org/abstracts/search?q=tPA%20gene" title=" tPA gene"> tPA gene</a>, <a href="https://publications.waset.org/abstracts/search?q=uPA%20gene" title=" uPA gene"> uPA gene</a> </p> <a href="https://publications.waset.org/abstracts/24878/expression-of-upa-tpa-and-pai-1-in-calcified-aortic-valves" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24878.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">474</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">180</span> A Comparative CFD Study on the Hemodynamics of Flow through an Idealized Symmetric and Asymmetric Stenosed Arteries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=B.%20Prashantha">B. Prashantha</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Anish"> S. Anish</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the present study is to computationally evaluate the hemodynamic factors which affect the formation of atherosclerosis and plaque rupture in the human artery. An increase of atherosclerosis disease in the artery causes geometry changes, which results in hemodynamic changes such as flow separation, reattachment, and adhesion of new cells (chemotactic) in the artery. Hence, geometry plays an important role in the determining the nature of hemodynamic patterns. Influence of stenosis in the non-bifurcating artery, under pulsatile flow condition, has been studied on an idealized geometry. Analysis of flow through symmetric and asymmetric stenosis in the artery revealed the significance of oscillating shear index (OSI), flow separation, low WSS zones and secondary flow patterns on plaque formation. The observed characteristic of flow in the post-stenotic region highlight the importance of plaque eccentricity on the formation of secondary stenosis on the arterial wall. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=atherosclerotic%20plaque" title="atherosclerotic plaque">atherosclerotic plaque</a>, <a href="https://publications.waset.org/abstracts/search?q=oscillatory%20shear%20index" title=" oscillatory shear index"> oscillatory shear index</a>, <a href="https://publications.waset.org/abstracts/search?q=stenosis%20nature" title=" stenosis nature"> stenosis nature</a>, <a href="https://publications.waset.org/abstracts/search?q=wall%20shear%20stress" title=" wall shear stress"> wall shear stress</a> </p> <a href="https://publications.waset.org/abstracts/48939/a-comparative-cfd-study-on-the-hemodynamics-of-flow-through-an-idealized-symmetric-and-asymmetric-stenosed-arteries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48939.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">350</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">179</span> Risk Factors for Maternal and Neonatal Morbidities Associated with Operative Vaginal Deliveries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maria%20Reichenber%20Arcilla">Maria Reichenber Arcilla</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To determine the risk factors for maternal and neonatal complications associated with operative vaginal deliveries. Methods: A retrospective chart review of 435 patients who underwent operative vaginal deliveries was done. Patient profiles – age, parity, AOG, duration of labor – and outcomes – birthweight, maternal and neonatal complications - were tabulated and multivariable analysis and logistic regression were performed using SPSS® Statistics Base. Results and Conclusion: There was no significant difference in the incidence of maternal and neonatal complications between those that underwent vacuum and forceps extraction. Among the variables analysed, parity and duration of labor reached statistical significance. The odds of maternal complications were 3 times higher among nulliparous patients. Neonatal complications were seen in those whose labor lasted more than 9 hours. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=operative%20vaginal%20deliveries" title="operative vaginal deliveries">operative vaginal deliveries</a>, <a href="https://publications.waset.org/abstracts/search?q=maternal" title=" maternal"> maternal</a>, <a href="https://publications.waset.org/abstracts/search?q=neonatal" title=" neonatal"> neonatal</a>, <a href="https://publications.waset.org/abstracts/search?q=morbidity" title=" morbidity"> morbidity</a> </p> <a href="https://publications.waset.org/abstracts/11843/risk-factors-for-maternal-and-neonatal-morbidities-associated-with-operative-vaginal-deliveries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11843.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">406</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">178</span> The Evaluation of Caustic and Corrosive Poisoning in Children</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sabiha%20Sahin">Sabiha Sahin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: We have planned this study because of the increasing number of corrosive substance poisoning who admitted to the Pediatric Emergency Department. Method: 636 corrosive substance poisoning cases applied to the Osmangazi University PED between 1 January 2015 - 31 December 2017 were retrospectively analyzed. Results: 438 (69%) cases were male.The poisoning rate of groups 0-4 was significantly higher and occurred by accident. A total of 616 cases (96.9%) were poisoned by the oral route, and 20 cases were poisoned by inhalation.462 Patients were admitted to the hospital within an hour (72.8%). Of the 134 patients who had only erosion and redness around the mouth, 24 patients had salivation and dysphagia symptoms besides these. Of the 28 cases of 158 patients with symptoms, eusaphegeal stenosis was detected. on third day examination. Although there was no statistically significant correlation between esophageal stenosis and erosion and redness around the mouth, there was a statistically significant correlation between dysphagia and salivation between esophageal stenosis Conclusion: The increased salivation and the dysphagia are important signs of risk of devoloping esophageal stenosis at first examination corrosive poisoning in children. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=caustic" title="caustic">caustic</a>, <a href="https://publications.waset.org/abstracts/search?q=corrosive" title=" corrosive"> corrosive</a>, <a href="https://publications.waset.org/abstracts/search?q=poisoning" title=" poisoning"> poisoning</a>, <a href="https://publications.waset.org/abstracts/search?q=children" title=" children"> children</a> </p> <a href="https://publications.waset.org/abstracts/88933/the-evaluation-of-caustic-and-corrosive-poisoning-in-children" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/88933.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">160</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">177</span> Efficacy of Hemi-Facetectomy in Treatment of Lumbar Foraminal Stenosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Manoj%20Deepak">Manoj Deepak</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Mathivanan"> N. Mathivanan</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Venkatachalam"> K. Venkatachalam</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nerve root stenosis is one of the main cause for back pain. There are many methods both conservative and surgical to treat this disease. It is pertinent to decompress the spine to a proper extent so as to avoid the recurrence of symptoms. But too much of an aggressive approach also has its disadvantages. We present one of the methods to effectively decompress the nerve with better results. Our study was carried out in 52 patients with foramina stenosis between 2008 to 2011.We carried out the surgical procedure of shaving off the medial part of the facet joint so as to decompress the root. We selected those patients who had symptoms of claudication for more than 2 years. They had no signs of instability and they underwent conservative treatment for a period of 2 months before the procedure. Oswersty scoring was used to record the functional level of the patient before and after the procedure. All patients were followed up for a period of minimum 2.5 years. After evaluation for a minimum of 2.5 years, 34 patients had no evidence of recurrence of symptoms with improvement in the functional level.7 patients complained of minimal pain but their functional quality had improved postop. Six patients had symptoms of lumbar canal disease which reduced with conservative treatment. 5 patients required spinal fusion surgeries in the later period. Conclusion: Thus, we can effectively conclude that our procedure is safe and effective in reducing the symptoms in those patients with neurogenic claudication. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=facetectoemy" title="facetectoemy">facetectoemy</a>, <a href="https://publications.waset.org/abstracts/search?q=stenosis" title=" stenosis"> stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=decompression" title=" decompression"> decompression</a>, <a href="https://publications.waset.org/abstracts/search?q=Lumbar%20Foraminal%20Stenosis" title=" Lumbar Foraminal Stenosis"> Lumbar Foraminal Stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=hemi-facetectomy" title=" hemi-facetectomy"> hemi-facetectomy</a> </p> <a href="https://publications.waset.org/abstracts/15953/efficacy-of-hemi-facetectomy-in-treatment-of-lumbar-foraminal-stenosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15953.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">350</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">176</span> Rate, Indication and Outcome of Operative Vaginal Delivery at Mayo University Hospital 2022</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammed%20Mustafa">Mohammed Mustafa</a>, <a href="https://publications.waset.org/abstracts/search?q=Fatima%20Abusin"> Fatima Abusin</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariam%20Abufatema"> Mariam Abufatema</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: This audit aims to evaluate the practices and outcomes of operative vaginal deliveries (OPVD) at Mayo University Hospital, focusing on identifying trends, complications, and adherence to clinical guidelines. Methods: A retrospective review was conducted on all cases of operative vaginal deliveries at Mayo University Hospital over one year. Data was collected from patient records, including demographics, OPVD indications, types of instruments used (forceps or vacuum), maternal and neonatal outcomes, and any associated complications. Statistical analyses were performed to assess the rates of successful and unsuccessful OPVDs and identify factors influencing outcomes. Results: The study included 159 [out of 174 total OPVD in 1 year] cases of operative vaginal deliveries. The indications predominantly consisted of the prolonged second stage of labor, fetal distress and suspicious CTG. The success rate of OVD was [97.5%]; maternal perineal tears [10 cases], hemorrhage[43 cases] and neonatal outcomes needed for SCBU admission[12 cases] were also assessed. Conclusion: This audit provides insights into the current practices and outcomes of operative vaginal deliveries at Mayo University Hospital. The findings underline the importance of adherence to clinical guidelines and highlight areas for potential improvement in practice <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=OPVD%20operative%20vaginal%20delivery" title="OPVD operative vaginal delivery">OPVD operative vaginal delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=GTG%20green%20top%20guidelines" title=" GTG green top guidelines"> GTG green top guidelines</a>, <a href="https://publications.waset.org/abstracts/search?q=PPH%20postpartum%20hemorrhage" title=" PPH postpartum hemorrhage"> PPH postpartum hemorrhage</a>, <a href="https://publications.waset.org/abstracts/search?q=SCBU%20special%20care%20baby%20unit" title=" SCBU special care baby unit"> SCBU special care baby unit</a> </p> <a href="https://publications.waset.org/abstracts/194009/rate-indication-and-outcome-of-operative-vaginal-delivery-at-mayo-university-hospital-2022" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194009.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">9</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">175</span> Establishment of a Nomogram Prediction Model for Postpartum Hemorrhage during Vaginal Delivery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yinglisong">Yinglisong</a>, <a href="https://publications.waset.org/abstracts/search?q=Jingge%20Chen"> Jingge Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Jingxuan%20Chen"> Jingxuan Chen</a>, <a href="https://publications.waset.org/abstracts/search?q=Yan%20Wang"> Yan Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Hui%20Huang"> Hui Huang</a>, <a href="https://publications.waset.org/abstracts/search?q=Jing%20Zhnag"> Jing Zhnag</a>, <a href="https://publications.waset.org/abstracts/search?q=Qianqian%20Zhang"> Qianqian Zhang</a>, <a href="https://publications.waset.org/abstracts/search?q=Zhenzhen%20Zhang"> Zhenzhen Zhang</a>, <a href="https://publications.waset.org/abstracts/search?q=Ji%20Zhang"> Ji Zhang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: The study aims to establish a nomogram prediction model for postpartum hemorrhage (PPH) in vaginal delivery. Patients and Methods: Clinical data were retrospectively collected from vaginal delivery patients admitted to a hospital in Zhengzhou, China, from June 1, 2022 - October 31, 2022. Univariate and multivariate logistic regression were used to filter out independent risk factors. A nomogram model was established for PPH in vaginal delivery based on the risk factors coefficient. Bootstrapping was used for internal validation. To assess discrimination and calibration, receiver operator characteristics (ROC) and calibration curves were generated in the derivation and validation groups. Results: A total of 1340 cases of vaginal delivery were enrolled, with 81 (6.04%) having PPH. Logistic regression indicated that history of uterine surgery, induction of labor, duration of first labor, neonatal weight, WBC value (during the first stage of labor), and cervical lacerations were all independent risk factors of hemorrhage (P <0.05). The area-under-curve (AUC) of ROC curves of the derivation group and the validation group were 0.817 and 0.821, respectively, indicating good discrimination. Two calibration curves showed that nomogram prediction and practical results were highly consistent (P = 0.105, P = 0.113). Conclusion: The developed individualized risk prediction nomogram model can assist midwives in recognizing and diagnosing high-risk groups of PPH and initiating early warning to reduce PPH incidence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vaginal%20delivery" title="vaginal delivery">vaginal delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=postpartum%20hemorrhage" title=" postpartum hemorrhage"> postpartum hemorrhage</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20factor" title=" risk factor"> risk factor</a>, <a href="https://publications.waset.org/abstracts/search?q=nomogram" title=" nomogram"> nomogram</a> </p> <a href="https://publications.waset.org/abstracts/174773/establishment-of-a-nomogram-prediction-model-for-postpartum-hemorrhage-during-vaginal-delivery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174773.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">77</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">174</span> Transvaginal Repair of Anterior Vaginal Wall Prolapse with Polyvinylidene Fluoride (PVDF) Mesh: An Alternative for Previously Restricted Materials</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad-Javad%20Eslami">Mohammad-Javad Eslami</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahtab%20Zargham"> Mahtab Zargham</a>, <a href="https://publications.waset.org/abstracts/search?q=Farshad%20Gholipour"> Farshad Gholipour</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammadreza%20Hajian"> Mohammadreza Hajian</a>, <a href="https://publications.waset.org/abstracts/search?q=Katayoun%20Bakhtiari"> Katayoun Bakhtiari</a>, <a href="https://publications.waset.org/abstracts/search?q=Sakineh%20Hajebrahimi"> Sakineh Hajebrahimi</a>, <a href="https://publications.waset.org/abstracts/search?q=Melina%20Eghbal"> Melina Eghbal</a>, <a href="https://publications.waset.org/abstracts/search?q=Ziba%20Farajzadegan"> Ziba Farajzadegan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: To study the mid-term safety and functional outcomes of transvaginal anterior vaginal wall prolapse repair using polyvinylidene fluoride (PVDF) mesh (DynaMesh®-PR4) by the double trans-obturator technique (TOT). Methods: Between 2015 and 2020, we prospectively included women with symptomatic high-stage anterior vaginal wall prolapse with or without uterine prolapse or stress urinary incontinence (SUI) in the study. The patients underwent transvaginal repair of the prolapse using PVDF mesh in two medical centers. We followed all patients for at least 12 months. We recorded the characteristics of vaginal and sexual symptoms, urinary incontinence, and prolapse stage pre- and postoperatively using International Consultation on Incontinence Questionnaire-Vaginal Symptoms (ICIQ-VS), International Consultation on Incontinence Questionnaire-Urinary Incontinence-Short Form (ICIQ-UI-SF), and Pelvic Organ Prolapse Quantification (POP-Q) system, respectively. Results: One hundred eight women were included in the final analysis with a mean follow-up time of 34.5 ± 18.6 months. The anatomical success was achieved in 103 (95.4%) patients. There was a significant improvement in patients’ vaginal symptoms, urinary incontinence, and quality of life scores postoperatively (p < 0.0001). Only six patients (5.5%) had mesh extrusion, five of whom were managed successfully. The total rates of complications and de novo urinary symptoms were 21.3% and 7.4%, respectively. Significant pain was reported in 17 cases (15.7%). Conclusion: Our findings show that using PVDF mesh in the double TOT technique for anterior vaginal wall prolapse repair is a safe procedure with high anatomic and functional success rates and acceptable complication rates in mid-term follow-up. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress%20urinary%20incontinence%20%28SU" title="stress urinary incontinence (SU">stress urinary incontinence (SU</a>, <a href="https://publications.waset.org/abstracts/search?q=incontinence%20questionnaire-vaginal%20symptoms%20%28ICIQ-VS%29" title=" incontinence questionnaire-vaginal symptoms (ICIQ-VS)"> incontinence questionnaire-vaginal symptoms (ICIQ-VS)</a>, <a href="https://publications.waset.org/abstracts/search?q=polyvinylidene%20fluoride%20%28PVDF%29%20mes" title=" polyvinylidene fluoride (PVDF) mes"> polyvinylidene fluoride (PVDF) mes</a>, <a href="https://publications.waset.org/abstracts/search?q=double%20trans-obturator%20technique%20%28TOT%29" title=" double trans-obturator technique (TOT)"> double trans-obturator technique (TOT)</a> </p> <a href="https://publications.waset.org/abstracts/187036/transvaginal-repair-of-anterior-vaginal-wall-prolapse-with-polyvinylidene-fluoride-pvdf-mesh-an-alternative-for-previously-restricted-materials" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187036.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">46</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">173</span> Geometrical Fluid Model for Blood Rheology and Pulsatile Flow in Stenosed Arteries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Karan%20Kamboj">Karan Kamboj</a>, <a href="https://publications.waset.org/abstracts/search?q=Vikramjeet%20Singh"> Vikramjeet Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=Vinod%20Kumar"> Vinod Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Considering blood to be a non-Newtonian Carreau liquid, this indirect numerical model investigates the pulsatile blood flow in a constricted restricted conduit that has numerous gentle stenosis inside the view of an increasing body speed. Asymptotic answers are obtained for the flow rate, pressure inclination, speed profile, sheer divider pressure, and longitudinal impedance to stream after the use of the twofold irritation approach to the problem of the succeeding non-straight limit esteem. It has been observed that the speed of the blood increases when there is an increase in the point of tightening of the conduit, the body speed increase, and the power regulation file. However, this rheological manner of behaving changes to one of longitudinal impedance to stream and divider sheer pressure when each of the previously mentioned boundaries increases. It has also been seen that the sheer divider pressure in the bloodstream greatly increases when there is an increase in the maximum depth of the stenosis but that it significantly decreases when there is an increase in the pulsatile Reynolds number. This is an interesting phenomenon. The assessments of the amount of growth in the longitudinal resistance to flow increase overall with the increment of the maximum depth of the stenosis and the Weissenberg number. Additionally, it is noted that the average speed of blood increases noticeably with the growth of the point of tightening of the corridor, and body speed increases border. This is something that can be observed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=geometry%20of%20artery" title="geometry of artery">geometry of artery</a>, <a href="https://publications.waset.org/abstracts/search?q=pulsatile%20blood%20flow" title=" pulsatile blood flow"> pulsatile blood flow</a>, <a href="https://publications.waset.org/abstracts/search?q=numerous%20stenosis" title=" numerous stenosis"> numerous stenosis</a> </p> <a href="https://publications.waset.org/abstracts/154359/geometrical-fluid-model-for-blood-rheology-and-pulsatile-flow-in-stenosed-arteries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/154359.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">99</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">172</span> Associations of Vitamin D Receptor Polymorphisms with Coronary Artery Diseases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elham%20Sharif">Elham Sharif</a>, <a href="https://publications.waset.org/abstracts/search?q=Nasser%20Rizk"> Nasser Rizk</a>, <a href="https://publications.waset.org/abstracts/search?q=Sirin%20Abu%20Aqel"> Sirin Abu Aqel</a>, <a href="https://publications.waset.org/abstracts/search?q=Ofelia%20Masoud"> Ofelia Masoud</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Previous studies have investigated the association of rs1544410, rs7975232 and rs731236 polymorphisms in vitamin D receptor gene and its impact on diseases such as cancer, diabetes and hypertension in different ethnic backgrounds. Aim: The aim of this study is to investigate the association between VDR polymorphisms using three SNP’s (rs1544410, rs7975232 and rs731236) and the severity of the significant lesion in coronary arteries among angiographically diagnosed CAD. Methods: A prospective-retrospective study was conducted on 192 CAD patients enrolled from the cardiology department-Heart Hospital HMC, grouped in 96 subjects with significant stenosis and 96 with non-significant stenosis with a mean age between 30 and 75 years old. Genotyping was performed for the following SNPs rs1544410, rs7975232 and rs731236 using TaqMan assay by the Real Time PCR, ABI 7500 in Health Sciences Labs at Qatar University Biomedical Research Center. Results: The results showed that both groups have matched age and gender distribution but patients with the significant stenosis have significantly higher; BMI (p=0.047); smoking status (p=0.039); FBS (p= 0.031); CK-MB (p=0.025) and Troponin (p=0.002) than the patients with non–significant lesion. Among the traditional risk factors, smoking increases the odds of the severe stenotic lesion in CAD patients by 1.984, with 95% CI between 1.024 – 7.063, with p= 0.042.HWE showed deviations of the rs1544410 and rs731236 among the study subjects. The most frequent genotype in distribution of rs7975232 is the AA among the significant stenosis patients, while the heterozygous AC was the frequent genotype in distribution among the non-significant stenosis group. The carriers of CC genotype in rs7975232 increased the risk of having significant coronary arteries stenotic lesion by 1.83 with 95% CI (1.020 – 3.280), p=0.043. No association was found between the rs7975232 with vitamin D and VDBP. Conclusion: There is a significant association between rs7975232 and the severity of CAD lesion. The carrier of CC genotype in rs7975232 increased the risk of having significant coronary arteries atherosclerotic lesion especially in patients with smoking history independent of vitamin D. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D" title="vitamin D">vitamin D</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D%20receptor" title=" vitamin D receptor"> vitamin D receptor</a>, <a href="https://publications.waset.org/abstracts/search?q=polymorphism" title=" polymorphism"> polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=coronary%20harat%20disease" title=" coronary harat disease"> coronary harat disease</a> </p> <a href="https://publications.waset.org/abstracts/48048/associations-of-vitamin-d-receptor-polymorphisms-with-coronary-artery-diseases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48048.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">313</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">171</span> It Is Time to Perform Total Laparoscopic Hysterectomy (TLH) without the Use of Uterine Manipulator: Kamran's TLH</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20Gendia">Ahmed Gendia</a>, <a href="https://publications.waset.org/abstracts/search?q=Waseem%20Kamran"> Waseem Kamran </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: Total Laparoscopic hysterectomy (TLH) remains a common approach among laparoscopic surgeons. However, this approach depends on the use of uterine manipulator to facilitate the surgery. Although many studies reported the effectiveness of TLH with uterine manipulator, only few reported TLH without the use of any uterine or vaginal manipulation. the aim of this report is to demonstrate our Technique (kamran's TLH) in performing TLH without the use of any uterine or vaginal manipulation in benign conditions and report our intra- and post-operative outcomes. Methodology : surgical technique will be demonstrated through a short video highlighting the easy and safe to learn surgical steps. Additionally, the data of 86 patients who underwent KTLH for benign condition were retrospectively analyzed. the data included intra- and postoperative finding and complications. Results : A total of 86 hysterectomies were performed utilizing the Kamran's TLH ( KTHL). Mean age was 52.2 (±11) years old and BMI was 28.2(±7). Mean operative time was 64.7(±27.9) minutes and estimated bloods loss was 46.2(±54.6) ml. No intraoperative complications were recorded and there was no conversion to open surgery. Only one patient required readmission and surgery for vaginal vault dehiscence. Conclusion & Significance: Uterine manipulator is a key component in performing laparoscopic hysterectomy. However, our approach demonstrated that TLH can be safely performed without the use of any uterine or vaginal manipulation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=laparoscopic%20hystrectomy" title="laparoscopic hystrectomy">laparoscopic hystrectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=TLH" title=" TLH"> TLH</a>, <a href="https://publications.waset.org/abstracts/search?q=uterine%20manipulator" title=" uterine manipulator"> uterine manipulator</a>, <a href="https://publications.waset.org/abstracts/search?q=surgery" title=" surgery "> surgery </a> </p> <a href="https://publications.waset.org/abstracts/128639/it-is-time-to-perform-total-laparoscopic-hysterectomy-tlh-without-the-use-of-uterine-manipulator-kamrans-tlh" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/128639.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">156</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">170</span> Evaluation of Non-Pharmacological Method-Transcervical Foley Catheter and Misoprostol to Intravaginal Misoprostol for Preinduction Cervical Ripening</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Krishna%20Dahiya">Krishna Dahiya</a>, <a href="https://publications.waset.org/abstracts/search?q=Esha%20Charaya"> Esha Charaya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Induction of labour is a common obstetrical intervention. Around 1 in every 4 patient undergo induction of labour for different indications Purpose: To study the efficacy of the combination of Foley bulb and vaginal misoprostol in comparison to vaginal misoprostol alone for cervical ripening and induction of labour. Methods: A prospective randomised study was conducted on 150 patients with term singleton pregnancy admitted for induction of labour. Seventy-five patients were induced with both Foley bulb, and vaginal misoprostol and another 75 were given vaginal misoprostol alone for induction of labour. Both groups were then compared with respect to change in Bishop score, induction to the active phase of labour interval, induction delivery interval, duration of labour, maternal complications and neonatal outcomes. Data was analysed using statistical software SPSS version 11.5. Tests with P,.05 were considered significant. Results: The two groups were comparable with respect to maternal age, parity, gestational age, indication for induction, and initial Bishop scores. Both groups had a significant change in Bishop score (2.99 ± 1.72 and 2.17 ± 1.48 respectively with statistically significant difference (p=0.001 S, 95% C.I. -0.1978 to 0.8378). Mean induction to delivery interval was significantly lower in the combination group (11.76 ± 5.89 hours) than misoprostol group (14.54 ± 7.32 hours). Difference was of 2.78 hours (p=0.018,S, 95% CI -5.1042 to -0.4558). Induction to delivery interval was significantly lower in nulliparous women of combination group (13.64 ± 5.75 hours) than misoprostol group (18.4±7.09 hours), and the difference was of 4.76 hours (p=0.002, S, 95% CI 1.0465 to 14.7335). There was no difference between the groups in the mode of delivery, infant weight, Apgar score and intrapartum complications. Conclusion: From the present study it was concluded that addition of Foley catheter to vaginal misoprostol have the synergistic effect and results in early cervical ripening and delivery. These results suggest that the combination may be used to achieve timely and safe delivery in the presence of an unfavorable cervix. A combination of the Foley bulb and vaginal misoprostol resulted in a shorter induction-to-delivery time when compared with vaginal misoprostol alone without increasing labor complications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bishop%20score" title="Bishop score">Bishop score</a>, <a href="https://publications.waset.org/abstracts/search?q=Foley%20catheter" title=" Foley catheter"> Foley catheter</a>, <a href="https://publications.waset.org/abstracts/search?q=induction%20of%20labor" title=" induction of labor"> induction of labor</a>, <a href="https://publications.waset.org/abstracts/search?q=misoprostol" title=" misoprostol"> misoprostol</a> </p> <a href="https://publications.waset.org/abstracts/68596/evaluation-of-non-pharmacological-method-transcervical-foley-catheter-and-misoprostol-to-intravaginal-misoprostol-for-preinduction-cervical-ripening" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68596.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">306</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">169</span> Pregnancy and Birth Experience, Opinions regarding the Delivery Method of the Patients' Vaginal Deliveries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Umran%20Erciyes">Umran Erciyes</a>, <a href="https://publications.waset.org/abstracts/search?q=Filiz%20Okumus"> Filiz Okumus</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of this study was the determination of factors which impact the pregnancy, birth experience and the opinions regarding the delivery type of the puerperants, after vaginal birth. This descriptive study includes 349 patients who gave births with normal birth in one of the hospital in İstanbul in May- November 2014. After birth, we interview with these women face to face. The descriptive information form and Perception of Birth Scale were used as data collection tool. SPSS (Statistical Package for the Social Sciences) was used for statistical analysis. The average age of patients was 27.13, and the average score was 76.93±20.22. The patients are primary school graduate, and they do not have a job. They expressed an income outcome equality. More than half of women did not get educated before birth. Among educated patients, few women got educated overcoming the pain during labor process. As the time spent in the hospital for the birth increases, the birth perception of mothers is affected negatively. %86.8 of participants gave assisted delivery. Spontaneous vaginal birth has positive effects on birth perception. Establishing a vascular access, induction of labor performing enema, restriction of orally intake and movement, fundal pressure, episiotomy, nor to perform skin to skin contact with the baby after birth has adverse effects on the birth perceptions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antenatal%20care" title="antenatal care">antenatal care</a>, <a href="https://publications.waset.org/abstracts/search?q=birth%20experience" title=" birth experience"> birth experience</a>, <a href="https://publications.waset.org/abstracts/search?q=perception%20of%20birth" title=" perception of birth"> perception of birth</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20birth" title=" vaginal birth"> vaginal birth</a> </p> <a href="https://publications.waset.org/abstracts/59559/pregnancy-and-birth-experience-opinions-regarding-the-delivery-method-of-the-patients-vaginal-deliveries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59559.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">437</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">168</span> Isolation and Antifungal Susceptibility Pattern of Candida albicans from Endocervical and High Vaginal Swabs of Pregnant Women Attending State Specialist Hospital Gombe, Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Isa%20Shu%E2%80%99aibu">Isa Shu’aibu</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20A.%20Mu%E2%80%99inat"> A. A. Mu’inat</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20U.%20Maigari"> F. U. Maigari</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Mani"> M. A. Mani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Candida albicans is the common cause of both oral and vaginal candidiasis in humans. This candidiasis leads to a wide range of physical, psychological and even physiological problems in humans particularly pregnant women. Samples of endocervical and high vaginal swab were collected from 200 women attending Gombe Specialist Hospital and inoculated on Saboraud Dextrose Agar (SDA) incorporated with chloramphenicol to get rid of the unwanted bacterial contaminants. Gram staining technique and germ tube test were employed for the identification, as Candida albicans is positive for both. Gram positive samples were 70% (n=140) and were further subjected to germ tube test. The remaining 30% (n=60) were found to be Gram negative. 90% (n=126) of the Gram positive ones isolated were also found to be positive for germ tube test; confirming the presence of Candida albicans. Antifungal susceptibility testing revealed that members of Imidazole (Ketoconazole, Miconazole) and those of Triazoles (Fluconazole and Itraconazole) were found to be more effective at concentrations of 20, 50 and 100 µg/disc compared to Griseofulvin (Fulcin) with only 26.00 mm zone of inhibition at 100 µg/disc concentration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Candida%20albicans" title="Candida albicans">Candida albicans</a>, <a href="https://publications.waset.org/abstracts/search?q=candidiasis" title=" candidiasis"> candidiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=endocervical" title=" endocervical"> endocervical</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20swab" title=" vaginal swab"> vaginal swab</a>, <a href="https://publications.waset.org/abstracts/search?q=antifungal%20susceptibility" title=" antifungal susceptibility"> antifungal susceptibility</a>, <a href="https://publications.waset.org/abstracts/search?q=imidazole" title=" imidazole"> imidazole</a>, <a href="https://publications.waset.org/abstracts/search?q=triazoles" title=" triazoles "> triazoles </a> </p> <a href="https://publications.waset.org/abstracts/13954/isolation-and-antifungal-susceptibility-pattern-of-candida-albicans-from-endocervical-and-high-vaginal-swabs-of-pregnant-women-attending-state-specialist-hospital-gombe-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13954.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">332</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">167</span> Predictors of Clinical Failure After Endoscopic Lumbar Spine Surgery During the Initial Learning Curve</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Daniel%20Scherman">Daniel Scherman</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniel%20Madani"> Daniel Madani</a>, <a href="https://publications.waset.org/abstracts/search?q=Shanu%20Gambhir"> Shanu Gambhir</a>, <a href="https://publications.waset.org/abstracts/search?q=Marcus%20Ling%20Zhixing"> Marcus Ling Zhixing</a>, <a href="https://publications.waset.org/abstracts/search?q=Yingda%20Li"> Yingda Li</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: This study aims to identify clinical factors that may predict failed endoscopic lumbar spine surgery to guide surgeons with patient selection during the initial learning curve. Methods: This is an Australasian prospective analysis of the first 105 patients to undergo lumbar endoscopic spine decompression by 3 surgeons. Modified MacNab outcomes, Oswestry Disability Index (ODI) and Visual Analogue Score (VAS) scores were utilized to evaluate clinical outcomes at 6 months postoperatively. Descriptive statistics and Anova t-tests were performed to measure statistically significant (p<0.05) associations between variables using GraphPad Prism v10. Results: Patients undergoing endoscopic lumbar surgery via an interlaminar or transforaminal approach have overall good/excellent modified MacNab outcomes and a significant reduction in post-operative VAS and ODI scores. Regardless of the anatomical location of disc herniations, good/excellent modified MacNab outcomes and significant reductions in VAS and ODI were reported post-operatively; however, not in patients with calcified disc herniations. Patients with central and foraminal stenosis overall reported poor/fair modified MacNab outcomes. However, there were significant reductions in VAS and ODI scores post-operatively. Patients with subarticular stenosis or an associated spondylolisthesis reported good/excellent modified MacNab outcomes and significant reductions in VAS and ODI scores post-operatively. Patients with disc herniation and concurrent degenerative stenosis had generally poor/fair modified MacNab outcomes. Conclusion: The outcomes of endoscopic spine surgery are encouraging, with a low complication and reoperation rate. However, patients with calcified disc herniations, central canal stenosis or a disc herniation with concurrent degenerative stenosis present challenges during the initial learning curve and may benefit from traditional open or other minimally invasive techniques. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=complications" title="complications">complications</a>, <a href="https://publications.waset.org/abstracts/search?q=lumbar%20disc%20herniation" title=" lumbar disc herniation"> lumbar disc herniation</a>, <a href="https://publications.waset.org/abstracts/search?q=lumbar%20endoscopic%20spine%20surgery" title=" lumbar endoscopic spine surgery"> lumbar endoscopic spine surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=predictors%20of%20failed%20endoscopic%20spine%20surgery" title=" predictors of failed endoscopic spine surgery"> predictors of failed endoscopic spine surgery</a> </p> <a href="https://publications.waset.org/abstracts/181406/predictors-of-clinical-failure-after-endoscopic-lumbar-spine-surgery-during-the-initial-learning-curve" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/181406.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">154</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">166</span> Characteristics of Patients Undergoing Subclavian Artery Revascularization in Latvia: A Retrospective Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Majid%20Shahbazi">Majid Shahbazi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Subclavian artery stenosis (SAS) is a common vascular disease that can cause a range of symptoms, from arm fatigue and weakness to ischemic stroke. Revascularization procedures, such as percutaneous transluminal angioplasty and stenting, are widely used to treat SAS and improve blood flow to the affected arm. However, the optimal management of patients with SAS is still unclear, and further research is needed to evaluate the safety and efficacy of different treatment options. This study aims to investigate the characteristics of patients with SAS who underwent revascularization procedures in Latvia (Specifically RAKUS). The research part of this paper aims to describe and analyze the demographics, comorbidities, diagnostic methods, types of revascularization procedures, and antiaggregant therapy used. The goal of this study is to provide insights into the current clinical practice in Latvia and help future treatment decision-makers. To achieve this aim, a retrospective study of 76 patients with SAS who underwent revascularization procedures was performed. After statistical analysis of the data, the study provided insights into the characteristics and management of patients with SAS in Latvia, highlighting the most observed comorbidities in these patients, the preferred diagnostic methods, and the most performed procedures. These findings can inform clinical decision-making and may have implications for the management of patients with subclavian artery stenosis in Latvia. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=subclavian%20artery%20stenosis" title="subclavian artery stenosis">subclavian artery stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=revascularization" title=" revascularization"> revascularization</a>, <a href="https://publications.waset.org/abstracts/search?q=characteristics%20of%20patients" title=" characteristics of patients"> characteristics of patients</a>, <a href="https://publications.waset.org/abstracts/search?q=comorbidities" title=" comorbidities"> comorbidities</a>, <a href="https://publications.waset.org/abstracts/search?q=retrospective%20analysis" title=" retrospective analysis"> retrospective analysis</a> </p> <a href="https://publications.waset.org/abstracts/166432/characteristics-of-patients-undergoing-subclavian-artery-revascularization-in-latvia-a-retrospective-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166432.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">95</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">165</span> Lactic Acid, Citric Acid, and Potassium Bitartrate Non-Hormonal Prescription Vaginal PH Modulator Gel for the Prevention of Pregnancy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shanna%20Su">Shanna Su</a>, <a href="https://publications.waset.org/abstracts/search?q=Kathleen%20Vincent"> Kathleen Vincent</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: A non-hormonal prescription vaginal pH modulator (VPM) gel (Phexxi®), with active ingredients lactic acid, citric acid, and potassium bitartrate, has recently been approved for the prevention of pregnancy in the United States. The objective of this review is to compile the evidence available from published preclinical and clinical trials to support its use. Areas covered: PubMed was searched for published literature on VPM gel. Two Phase III trials were found on the clinicaltrials.gov database. The results demonstrated that VPM gel is safe, with minimal side effects, and effective (cumulative 6-7 cycle pregnancy rate of 4.1-13.65%, (Pearl Index 27.5) as a contraceptive. Microbicidal effects suggest the potential for the prevention of sexually transmitted infections (STIs); currently, a Phase III clinical trial is being conducted to evaluate the prevention of chlamydia and gonorrhea. Expert opinion: Non-hormonal reversible contraceptive options have been limited to the highly effective copper-releasing intrauterine device that requires insertion by a trained clinician and less effective coitally-associated barrier and spermicide options which are typically available over-the-counter. Spermicides, which improve the efficacy of barrier devices, may increase the risk of Human Immunodeficiency Virus (HIV)/STIs. VPM gel provides a new safe, effective non-hormonal contraceptive option with the potential for prevention of STIs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=citric%20acid" title="citric acid">citric acid</a>, <a href="https://publications.waset.org/abstracts/search?q=lactic%20acid" title=" lactic acid"> lactic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=non-hormonal%20contraception" title=" non-hormonal contraception"> non-hormonal contraception</a>, <a href="https://publications.waset.org/abstracts/search?q=potassium%20bitartrate" title=" potassium bitartrate"> potassium bitartrate</a>, <a href="https://publications.waset.org/abstracts/search?q=topical%20vaginal%20contraceptive" title=" topical vaginal contraceptive"> topical vaginal contraceptive</a>, <a href="https://publications.waset.org/abstracts/search?q=vaginal%20pH%20modulator%20gel" title=" vaginal pH modulator gel"> vaginal pH modulator gel</a> </p> <a href="https://publications.waset.org/abstracts/152486/lactic-acid-citric-acid-and-potassium-bitartrate-non-hormonal-prescription-vaginal-ph-modulator-gel-for-the-prevention-of-pregnancy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152486.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">100</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">164</span> A Case Study on the Effectiveness of the Physical Therapy Home Exercise Program for Pelvic Floor Muscle Training in a Middle-Aged Female Post- Surgical Repair of Stage III Pelvic Organ Prolapse</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Iwona%20Kasior">Iwona Kasior</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: Pelvic organ prolapse is the descent of pelvic organs into the vaginal opening. Currently, few trials have been conducted to determine the influence of pelvic floor muscle training in decreasing stage or symptoms associated with pelvic organ prolapse. The purpose of this case study is to determine whether pelvic floor muscle training can decrease the stage of pelvic organ prolapse and related symptoms. Case Presentation: This is the case of a 55-year-old female; recently diagnosed with midline cystocele, stage three. She has undergone corrective surgery that failed. She has now resorted to managing the condition with a home exercise regimen of voluntary pelvic floor muscle contractions, topical vaginal crème prescribed by her gynecologist, and slight lifestyle modifications. Methods: The patient was treated by a physical therapist for evaluation, vaginal exam, and educated in the ‘knack’ maneuver, lifestyle modifications, and proper technique of performing pelvic floor muscle contractions. The subject continued with a home exercise program with a specific regimen of pelvic floor muscle contractions and topical vaginal crème. Outcome: As determined by her physical therapist and the subject, her pelvic floor muscle strength had increased following the pelvic floor muscle training regimen and the use of the ‘knack’ maneuver. The subject reported a small decrease in the size of bulging prolapse and related symptoms of dryness, odor, vaginal discomfort, and the sensation of descent. Conclusion: Pelvic floor muscle training helped to lessen the degree of the prolapse, but not significantly enough to decrease the diagnosed stage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kegel%20exercises" title="Kegel exercises">Kegel exercises</a>, <a href="https://publications.waset.org/abstracts/search?q=pelvic%20floor" title=" pelvic floor"> pelvic floor</a>, <a href="https://publications.waset.org/abstracts/search?q=pelvic%20organ%20prolapse" title=" pelvic organ prolapse"> pelvic organ prolapse</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20therapy" title=" physical therapy"> physical therapy</a> </p> <a href="https://publications.waset.org/abstracts/138123/a-case-study-on-the-effectiveness-of-the-physical-therapy-home-exercise-program-for-pelvic-floor-muscle-training-in-a-middle-aged-female-post-surgical-repair-of-stage-iii-pelvic-organ-prolapse" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138123.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">194</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">163</span> Prevalence and Comparison for Detection Methods of Candida Species in Vaginal Specimens from Pregnant and Non-Pregnant Saudi Women</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yazeed%20Al-Sheikh">Yazeed Al-Sheikh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pregnancy represents a risk factor in the occurrence of vulvovaginal candidiasis. To investigate the prevalence rate of vaginal carriage of Candida species in Saudi pregnant and non-pregnant women, high vaginal swab (HVS) specimens (707) were examined by direct microscopy (10% KOH and Giemsa staining) and parallel cultured on Sabouraud Dextrose Agar (SDA) as well as on “CHROM agar Candida” medium. As expected, Candida-positive cultures were frequently observed in pregnant-test group (24%) than in non-pregnant group (17%). The frequency of culture positive was correlated to pregnancy (P=0.047), parity (P=0.001), use of contraceptive (P=0.146), or antibiotics (P=0.128), and diabetic-patients (P < 0.0001). Out of 707 HVS examined specimens, 157 specimens were yeast-positive culture (22%) on Sabouraud Dextrose Agar or “CHROM agar Candida”. In comparison, the sensitivities of the direct 10% KOH and the Giemsa stain microscopic examination methods were 84% (132/157) and 95% (149/157) respectively but both with 100% specificity. As for the identity of recovered 157 yeast isolates, based on API 20C biotype carbohydrate assimilation, germ tube and chlamydospore formation, C. albicansand C. glabrata constitute 80.3 and 12.7% respectively. Rates of C. tropicalis, C. kefyr, C. famata or C. utilis were 2.6, 1.3, and 0.6% respectively. Sachromyces cerevisiae and Rhodotorula mucilaginosa yeasts were also encountered at a frequency of 1.3 and 0.6% respectively. Finally, among all recovered 157 yeast-isolates, strains resistant to ketoconazole were not detected, whereas 5% of the C. albicans and as high as 55% of the non-albicans yeast isolates (majority C. glabrata) showed resistance to fluconazole. Our findings may prove helpful for continuous determination of the existing vaginal candidiasis causative species during pregnancy, its lab-diagnosis and/or control and possible measures to minimize the incidence of the disease-associated pre-term delivery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vaginal%20candidiasis" title="vaginal candidiasis">vaginal candidiasis</a>, <a href="https://publications.waset.org/abstracts/search?q=Candida%20spp." title=" Candida spp."> Candida spp.</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20factors" title=" risk factors"> risk factors</a>, <a href="https://publications.waset.org/abstracts/search?q=API%2020C-yeast%20biotypes" title=" API 20C-yeast biotypes"> API 20C-yeast biotypes</a>, <a href="https://publications.waset.org/abstracts/search?q=giemsa%20stain" title=" giemsa stain"> giemsa stain</a>, <a href="https://publications.waset.org/abstracts/search?q=antifungal%20agents" title=" antifungal agents"> antifungal agents</a> </p> <a href="https://publications.waset.org/abstracts/3375/prevalence-and-comparison-for-detection-methods-of-candida-species-in-vaginal-specimens-from-pregnant-and-non-pregnant-saudi-women" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3375.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">241</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">162</span> Use of Misoprostol in Pregnancy Termination in the Third Trimester: Oral versus Vaginal Route</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Saimir%20Cenameri">Saimir Cenameri</a>, <a href="https://publications.waset.org/abstracts/search?q=Arjana%20Tereziu"> Arjana Tereziu</a>, <a href="https://publications.waset.org/abstracts/search?q=Kastriot%20Dallaku"> Kastriot Dallaku</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Intra-uterine death is a common problem in obstetrical practice, and can lead to complications if left to resolve spontaneously. The cervix is unprepared, making inducing of labor difficult. Misoprostol is a synthetic prostaglandin E1 analogue, inexpensive, and is presented valid thanks to its ability to bring about changes in the cervix that lead to the induction of uterine contractions. Misoprostol is quickly absorbed when taken orally, resulting in high initial peak serum concentrations compared with the vaginal route. The vaginal misoprostol peak serum concentration is not as high and demonstrates a more gradual serum concentration decline. This is associated with many benefits for the patient; fast induction of labor; smaller doses; and fewer side effects (dose-depended). Mostly it has been used the regime of 50 μg/4 hour, with a high percentage of success and limited side effects. Objective: Evaluation of the efficiency of the use of oral and vaginal misoprostol in inducing labor, and comparing it with its use not by a previously defined protocol. Methods: Participants in this study included patients at U.H.O.G. 'Koco Gliozheni', Tirana from April 2004-July 2006, presenting with an indication for inducing labor in the third trimester for pregnancy termination. A total of 37 patients were randomly admitted for birth inducing activity, according to protocol (26), oral or vaginal protocol (10 vs. 16), and a control group (11), not subject to the protocol, was created. Oral or vaginal misoprostol was administered at a dose of 50 μg/4 h, while the fourth group participants were treated individually by the members of the medical staff. The main result of interest was the time between induction of labor to birth. Kruskal-Wallis test was used to compare the average age, parity, women weight, gestational age, Bishop's score, the size of the uterus and weight of the fetus between the four groups in the study. The Fisher exact test was used to compare day-stay and causes in the four groups. Mann-Whitney test was used to compare the time of the expulsion and the number of doses between oral and vaginal group. For all statistical tests used, the value of P ≤ 0.05 was considered statistically significant. Results: The four groups were comparable with regard to woman age and weight, parity, abortion indication, Bishop's score, fetal weight and the gestational age. There was significant difference in the percentage of deliveries within 24 hours. The average time from induction to birth per route (vaginal, oral, according to protocol and not according to the protocol) was respectively; 10.43h; 21.10h; 15.77h, 21.57h. There was no difference in maternal complications in groups. Conclusions: Use of vaginal misoprostol for inducing labor in the third trimester for termination of pregnancy appears to be more effective than the oral route, and even more to uses not according to the protocols approved before, where complications are greater and unjustified. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=inducing%20labor" title="inducing labor">inducing labor</a>, <a href="https://publications.waset.org/abstracts/search?q=misoprostol" title=" misoprostol"> misoprostol</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy%20termination" title=" pregnancy termination"> pregnancy termination</a>, <a href="https://publications.waset.org/abstracts/search?q=third%20trimester" title=" third trimester"> third trimester</a> </p> <a href="https://publications.waset.org/abstracts/76358/use-of-misoprostol-in-pregnancy-termination-in-the-third-trimester-oral-versus-vaginal-route" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/76358.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">185</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">161</span> Upregulation of CD40/CD40L System in Rheumatic Mitral Stenosis With or Without Atrial Fibrillation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Azzam%20H.">Azzam H.</a>, <a href="https://publications.waset.org/abstracts/search?q=Abousamra%20N.%20K."> Abousamra N. K.</a>, <a href="https://publications.waset.org/abstracts/search?q=Wafa%20A.%20A."> Wafa A. A.</a>, <a href="https://publications.waset.org/abstracts/search?q=Hafez%20M.%20M."> Hafez M. M.</a>, <a href="https://publications.waset.org/abstracts/search?q=El-Gilany%20A.%20H."> El-Gilany A. H.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Platelet activation occurs in peripheral blood of patients with rheumatic mitral stenosis (MS) and atrial fibrillation (AF) and could be related to abnormal thrombogenesis. The CD40/CD40 ligand (CD40L) which reflects platelet activation, mediate a central role in thrombotic diseases. However, the role of CD40/CD40L system in rheumatic MS with or without AF remains unclear. Expressions of CD40 on monocytes and CD40L on platelets were determined by whole blood flow cytometry and serum levels of soluble CD40L were measured by enzyme-linked immunosorbent assay in group 1 (19 patients with MS) and group 2 (20 patients with MS and AF) compared to group 3 (10 controls). Patients with groups 1 and 2 had a significant increase in expression of CD40 on monocytes (P1 and P2 = 0.000) and serum levels of sCD40L (P1 = 0.014 and P2 = 0.033, respectively), but nonsignificant increase in expression of CD40L on platelets (P1 = 0.109 and P2 = 0.060, respectively) as compared to controls. There were no significant difference in all the parameters in group 1 compared to group 2. Correlation analysis demonstrated that there was a significant direct relationship between the severity of MS and serum levels of sCD40L (r = -0.469, p = 0.043). In conclusion, rheumatic MS patients with or without AF had upregulation of the CD40/CD40L system as well as elevated sCD40L levels. The levels of sCD40L had a significantly direct relationship with the severity of MS and it was the stenotic mitral valve, not AF, that had a significant impact on platelet activation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CD40" title="CD40">CD40</a>, <a href="https://publications.waset.org/abstracts/search?q=CD40L" title=" CD40L"> CD40L</a>, <a href="https://publications.waset.org/abstracts/search?q=mitral%20stenosis" title=" mitral stenosis"> mitral stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=atrial%20fibrillation" title=" atrial fibrillation"> atrial fibrillation</a> </p> <a href="https://publications.waset.org/abstracts/158032/upregulation-of-cd40cd40l-system-in-rheumatic-mitral-stenosis-with-or-without-atrial-fibrillation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158032.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">95</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">160</span> Modified Preputial Urethrostomy as a Salvage Procedure in Four Dogs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Thomas%20Giansetto">Thomas Giansetto</a>, <a href="https://publications.waset.org/abstracts/search?q=Olivier%20Broux"> Olivier Broux</a>, <a href="https://publications.waset.org/abstracts/search?q=G%C3%A9raldine%20Bolen"> Géraldine Bolen</a>, <a href="https://publications.waset.org/abstracts/search?q=St%C3%A9phanie%20Claeys"> Stéphanie Claeys</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To describe a modified preputial urethrostomy in four dogs. Study design: Short case series. Animals: Four male dogs were treated by the modified preputial urethrostomy, three because of urethral stenosis, and one because of severe complications following perineal urethrostomy. Methods: Four dogs were presented for dysuria and urinary obstruction. secondary to urethral stenosis or tear. Obstruction was treated with a modified preputial urethrostomy. Results: Four dogs had resolution of dysuria with a modified preputial urethrostomy without penile amputation. None of the dogs presented signs of dysuria, urinary tract infection, or dermatitis postoperatively. Two dogs showed signs of urinary incontinence 15 days and one month postoperatively. Conclusion: The modified preputial urethrostomy resulted in a favorable prognosis and may be an alternative to prepubic urethrostomy in male dogs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=urethrostomy" title="urethrostomy">urethrostomy</a>, <a href="https://publications.waset.org/abstracts/search?q=preputial" title=" preputial"> preputial</a>, <a href="https://publications.waset.org/abstracts/search?q=technique" title=" technique"> technique</a>, <a href="https://publications.waset.org/abstracts/search?q=urogenital" title=" urogenital"> urogenital</a> </p> <a href="https://publications.waset.org/abstracts/149472/modified-preputial-urethrostomy-as-a-salvage-procedure-in-four-dogs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149472.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">168</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">159</span> Blood Flow in Stenosed Arteries: Analytical and Numerical Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shashi%20Sharma">Shashi Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Uaday%20Singh"> Uaday Singh</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20K.%20Katiyar"> V. K. Katiyar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Blood flow through a stenosed tube, which is of great interest to mechanical engineers as well as medical researchers. If stenosis exists in an artery, normal blood flow is disturbed. The deposition of fatty substances, cholesterol, cellular waste products in the inner lining of an artery results to plaque formation .The present study deals with a mathematical model for blood flow in constricted arteries. Blood is considered as a Newtonian, incompressible, unsteady and laminar fluid flowing in a cylindrical rigid tube along the axial direction. A time varying pressure gradient is applied in the axial direction. An analytical solution is obtained using the numerical inversion method for Laplace Transform for calculating the velocity profile of fluid as well as particles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=blood%20flow" title="blood flow">blood flow</a>, <a href="https://publications.waset.org/abstracts/search?q=stenosis" title=" stenosis"> stenosis</a>, <a href="https://publications.waset.org/abstracts/search?q=Newtonian%20fluid" title=" Newtonian fluid"> Newtonian fluid</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20biology%20and%20genetics" title=" medical biology and genetics"> medical biology and genetics</a> </p> <a href="https://publications.waset.org/abstracts/25427/blood-flow-in-stenosed-arteries-analytical-and-numerical-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25427.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> 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