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KEGG COMPOUND: C00533
<!doctype html> <html><head> <title>KEGG COMPOUND: C00533</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1739834473"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1739834473"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1739834473" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; 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if(document.getElementById('kcfb'+i)){ document.getElementById('kcfb'+i).onclick = function(e){toggleData(this,e);}; } } } function Link_XtrctSeq2(form) { var dna_from; var dna_to; var dna_len; var plus_up = Number(form.XtrctSeq_UP.value) ; var plus_down = Number(form.XtrctSeq_DOWN.value); var vector = Number(form.VECTOR.value); var org = form.ORG.value; var chr = form.CHR.value; var kid = form.KEGGID.value; var url; if (plus_up == 0 && plus_down == 0) { url = "/entry/-f+-n+n+" + kid; } else { if (vector == 1) { dna_from = Number(form.FROM.value) - plus_up; dna_to = Number(form.TO.value) + plus_down; } else { dna_from = Number(form.FROM.value) - plus_down; dna_to = Number(form.TO.value) + plus_up; } url = "/dbget-bin/cut_sequence_genes.pl?FROM=" + dna_from + "&TO=" + dna_to +"&VECTOR=" + vector + "&ORG=" + org; if (chr) url += "&CHR=" + chr; } //window.open( url, "_self" ); location.href = url; } function go_taxonomy(form,params){ for(var key in params){ if(form[key]){ 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id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr2 w1"> <table width="650" class="w2"> <tr><th class="th20 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td20 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">C00533 Compound <br> </span></code></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td21 defd"><div class="cel"><div class="cel">Nitric oxide;<br> NO;<br> Nitrogen monoxide<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Formula</span></th> <td class="td20 defd"><div class="cel">NO<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Exact mass</span></th> <td class="td21 defd"><div class="cel">29.9980<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Mol weight</span></th> <td class="td20 defd"><div class="cel">30.01<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Structure</span></th> <td class="td21 defd"><a href="/Fig/compound/C00533.gif"><img name="img0" src="/Fig/compound/C00533.gif" style="max-width:600px" border=0></a><br> <button class="btn" onclick="location.href='/entry/-f+m+C00533';return false;">Mol file</button><button class="btn" onclick="location.href='/entry/-f+k+C00533';return false;">KCF file</button><button class="btn" onclick="location.href='/tools-bin/strsearch_view?ENTRY=C00533&PROGRAM=simcomp&DATABASE=compound';return false;">DB search</button></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Remark</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">Same as: </span></td><td><a href="/entry/D00074">D00074</a></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reaction</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/R00111">R00111</a> <a href="/entry/R00280">R00280</a> <a href="/entry/R00294">R00294</a> <a href="/entry/R00557">R00557</a> <a href="/entry/R00783">R00783</a> <a href="/entry/R00784">R00784</a> <a href="/entry/R00785">R00785</a> <a href="/entry/R02492">R02492</a> <br> <a href="/entry/R05724">R05724</a> <a href="/entry/R05725">R05725</a> <a href="/entry/R09445">R09445</a> <a href="/entry/R09446">R09446</a> <a href="/entry/R09751">R09751</a> <a href="/entry/R09799">R09799</a> <a href="/entry/R09808">R09808</a> <a href="/entry/R09809">R09809</a> <br> <a href="/entry/R09996">R09996</a> <a href="/entry/R10106">R10106</a> <a href="/entry/R10108">R10108</a> <a href="/entry/R10165">R10165</a> <a href="/entry/R11711">R11711</a> <a href="/entry/R11713">R11713</a> <a href="/entry/R13417">R13417</a> <a href="/entry/R13422">R13422</a><br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Pathway</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map00330+C00533">map00330</a> </span></td><td>Arginine and proline metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map00910+C00533">map00910</a> </span></td><td>Nitrogen metabolism</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01100+C00533">map01100</a> </span></td><td>Metabolic pathways</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01120+C00533">map01120</a> </span></td><td>Microbial metabolism in diverse environments</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map01310+C00533">map01310</a> </span></td><td>Nitrogen cycle</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map02020+C00533">map02020</a> </span></td><td>Two-component system</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04022+C00533">map04022</a> </span></td><td>cGMP-PKG signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04066+C00533">map04066</a> </span></td><td>HIF-1 signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04071+C00533">map04071</a> </span></td><td>Sphingolipid signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04151+C00533">map04151</a> </span></td><td>PI3K-Akt signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04270+C00533">map04270</a> </span></td><td>Vascular smooth muscle contraction</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04370+C00533">map04370</a> </span></td><td>VEGF signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04371+C00533">map04371</a> </span></td><td>Apelin signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04540+C00533">map04540</a> </span></td><td>Gap junction</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04611+C00533">map04611</a> </span></td><td>Platelet activation</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04621+C00533">map04621</a> </span></td><td>NOD-like receptor signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04626+C00533">map04626</a> </span></td><td>Plant-pathogen interaction</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04713+C00533">map04713</a> </span></td><td>Circadian entrainment</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04730+C00533">map04730</a> </span></td><td>Long-term depression</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04915+C00533">map04915</a> </span></td><td>Estrogen signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04921+C00533">map04921</a> </span></td><td>Oxytocin signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04924+C00533">map04924</a> </span></td><td>Renin secretion</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04926+C00533">map04926</a> </span></td><td>Relaxin signaling pathway</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04931+C00533">map04931</a> </span></td><td>Insulin resistance</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04940+C00533">map04940</a> </span></td><td>Type I diabetes mellitus</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map04970+C00533">map04970</a> </span></td><td>Salivary secretion</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05010+C00533">map05010</a> </span></td><td>Alzheimer disease</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05014+C00533">map05014</a> </span></td><td>Amyotrophic lateral sclerosis</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05022+C00533">map05022</a> </span></td><td>Pathways of neurodegeneration - multiple diseases</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05140+C00533">map05140</a> </span></td><td>Leishmaniasis</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05142+C00533">map05142</a> </span></td><td>Chagas disease</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05143+C00533">map05143</a> </span></td><td>African trypanosomiasis</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05144+C00533">map05144</a> </span></td><td>Malaria</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05146+C00533">map05146</a> </span></td><td>Amoebiasis</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05171+C00533">map05171</a> </span></td><td>Coronavirus disease - COVID-19</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05200+C00533">map05200</a> </span></td><td>Pathways in cancer</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05225+C00533">map05225</a> </span></td><td>Hepatocellular carcinoma</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05330+C00533">map05330</a> </span></td><td>Allograft rejection</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05332+C00533">map05332</a> </span></td><td>Graft-versus-host disease</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05415+C00533">map05415</a> </span></td><td>Diabetic cardiomyopathy</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map05418+C00533">map05418</a> </span></td><td>Fluid shear stress and atherosclerosis</td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Module</span></th> <td class="td21 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/module/M00529+C00533">M00529</a> </span></td><td>Denitrification, nitrate => nitrogen</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/module/M00973+C00533">M00973</a> </span></td><td>Anammox, nitrite + ammonia => nitrogen</td></tr></table></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Network</span></th> <td class="td20 defd"><div class="cel"><a href="/network/nt06226+C00533">nt06226</a> KEAP1-NRF2 signaling (cancer)<br><a href="/network/nt06263+C00533">nt06263</a> Hepatocellular carcinoma<br><a href="/network/nt06463+C00533">nt06463</a> Parkinson disease<br><a href="/network/nt06521+C00533">nt06521</a> NLR signaling</div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Enzyme</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/1.7.1.14">1.7.1.14</a> <a href="/entry/1.7.2.1">1.7.2.1</a> <a href="/entry/1.7.2.5">1.7.2.5</a> <a href="/entry/1.7.2.7">1.7.2.7</a> <br> <a href="/entry/1.7.2.9">1.7.2.9</a> <a href="/entry/1.7.5.2">1.7.5.2</a> <a href="/entry/1.7.6.1">1.7.6.1</a> <a href="/entry/1.14.12.17">1.14.12.17</a> <br> <a href="/entry/1.14.13.39">1.14.13.39</a> <a href="/entry/1.14.14.47">1.14.14.47</a> <a href="/entry/1.14.15.41">1.14.15.41</a> <a href="/entry/1.14.15.42">1.14.15.42</a><br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Brite</span></th> <td class="td20 defd"><div class="cel"><span class="nowrap">Anatomical Therapeutic Chemical (ATC) classification [BR:<a href="/brite/br08303+D00074">br08303</a>]<br> R RESPIRATORY SYSTEM<br> R07 OTHER RESPIRATORY SYSTEM PRODUCTS<br> R07A OTHER RESPIRATORY SYSTEM PRODUCTS<br> R07AX Other respiratory system products<br> R07AX01 Nitric oxide<br> D00074 Nitric oxide (JAN/USAN) <JP/US><br> Therapeutic category of drugs in Japan [BR:<a href="/brite/br08301+D00074">br08301</a>]<br> 2 Agents affecting individual organs<br> 21 Cardiovascular agents<br> 219 Miscellaneous<br> 2190 Miscellaneous<br> D00074 Nitric oxide (JAN/USAN)<br> New drug approvals in the USA [<a href="/kegg/drug/br08319.html?id=D00074">br08319.html</a>]<br> New molecular entities and new therapeutic biological products<br> D00074<br> New drug approvals in Europe [<a href="/kegg/drug/br08329.html?id=D00074">br08329.html</a>]<br> European public assessment reports (EPAR) authorised medicine<br> D00074<br> New drug approvals in Japan [<a href="/kegg/drug/br08318.html?id=D00074">br08318.html</a>]<br> Drugs with new active ingredients<br> D00074<br> New drug approvals in the USA, Europe and Japan [<a href="/kegg/drug/br08328.html?id=D00074">br08328.html</a>]<br> Approval dates by FDA, EMA and PMDA<br> D00074<br> </span></div><button class="btn" onclick="location.href='/kegg-bin/search_brite?option=-a&search_string=C00533';return false;">BRITE hierarchy</button></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td21 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">CAS: </span></td><td>10102-43-9</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">PubChem: </span></td><td><a href="https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=3815">3815</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ChEBI: </span></td><td><a href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16480">16480</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">NIKKAJI: </span></td><td><a href="https://jglobal.jst.go.jp/en/redirect?Nikkaji_No=J161.349I">J161.349I</a></td></tr></table></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">KCF data</span></th> <td class="td20 defd"><button class="btn" id="kcfb1">Show</button><div class="kcfd" id="kcfd1"><br>ATOM 2<br> 1 O3a O 21.4046 -16.1648<br> 2 N2a N 22.8046 -16.1648 #^<br> BOND 1<br> 1 1 2 2<br> </div></td></tr> </table></td></tr></table> <br><span style="font-size:12px"><a href="/entry/cpd_ja:C00533">» Japanese version</a></span><br><br></td><td class="vtop"><div class="aw" style="margin-top:46px;"><div class="fm at th20"> All links </div> <div class="fm"><pre class="fm" style="margin-left:1em"> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+2+cpd:C00533">Pathway (43)</a></span> <a href="/dbget-bin/get_linkdb?-t+pathway+cpd:C00533">KEGG PATHWAY (41)</a> <a href="/dbget-bin/get_linkdb?-t+module+cpd:C00533">KEGG MODULE (2)</a> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+3+cpd:C00533">Network (6)</a></span> <a href="/dbget-bin/get_linkdb?-t+network+cpd:C00533">KEGG NETWORK (6)</a> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+5+cpd:C00533">Drug (1)</a></span> <a href="/dbget-bin/get_linkdb?-t+drug+cpd:C00533">KEGG DRUG (1)</a> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+6+cpd:C00533">Chemical substance (5)</a></span> <a href="/dbget-bin/get_linkdb?-t+pubchem+cpd:C00533">PubChem (1)</a> <a href="/dbget-bin/get_linkdb?-t+chebi+cpd:C00533">ChEBI (1)</a> <a href="/dbget-bin/get_linkdb?-t+hmdb+cpd:C00533">HMDB (1)</a> <a href="/dbget-bin/get_linkdb?-t+hsdb+cpd:C00533">HSDB (1)</a> <a href="/dbget-bin/get_linkdb?-t+nikkaji+cpd:C00533">NIKKAJI (1)</a> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+7+cpd:C00533">Chemical reaction (36)</a></span> <a href="/dbget-bin/get_linkdb?-t+enzyme+cpd:C00533">KEGG ENZYME (12)</a> <a href="/dbget-bin/get_linkdb?-t+reaction+cpd:C00533">KEGG REACTION (24)</a> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+9+cpd:C00533">Gene (10727)</a></span> <a href="/dbget-bin/get_linkdb?-t+genes+cpd:C00533">KEGG GENES (10727)</a> <a href="/dbget-bin/get_linkdb?-t+alldb+cpd:C00533">All databases (10818)</a> <br><a href="/dbget-bin/get_linkdb?-N+cpd:C00533">Download RDF</a> </pre> 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