Th茅lu | TIMC

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</div> </aside> <section class="col-sm-9"> <div class="highlighted"> <div class="region region-highlighted"> <div data-drupal-messages-fallback class="hidden"></div> </div> </div> <a id="main-content"></a> <div class="region region-content"> <article data-history-node-id="1589" role="article" about="/portrait/thelu-jacques" class="portrait is-promoted full clearfix"> <div class="content"> <div class="field field--name-field-portrait field--type-image field--label-hidden field--item"> <img src="/medias/2018-03/portrait-jacques-thelu-cnrs_1.png" width="189" height="265" alt="Jacques Th茅lu" typeof="foaf:Image" class="img-responsive" /> </div> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p class="text-align-justify"><br /> <strong>Jacques Th茅lu</strong> a rejoint l鈥櫭﹒uipe SyNaBi dirig茅e par Don Martin il y a tout juste un an. Ce choix a constitu茅 un nouveau grand 茅cart pour lui, un challenge qui lui pla卯t bien. En effet, la th茅matique Biopile est bien loin de ses pr茅c茅dents engagements en tant que chercheur CNRS. Au d茅marrage, sa formation de biochimiste le m猫ne sur le terrain de la bact茅riologie et de l鈥檈nzymologie dans l鈥櫭﹒uipe de Jean Pelmont. Il est passionn茅 par l鈥檌d茅e de valoriser le potentiel d茅polluant des bact茅ries gr芒ce 脿 leur 茅quipement enzymatique particulier. Un premier changement de direction au d茅but des ann茅es 80 le dirige vers la parasitologie dans le service hospitalier de Pierre Ambroise-Thomas, avec en particulier comme objectif la lutte contre le paludisme. Cette t芒che s鈥檃v猫re bien difficile puisque aujourd鈥檋ui encore aucun vaccin n鈥檈st totalement efficace. La p茅riode s'est r茅v茅l茅e cependant riche d鈥檈nseignements avec l鈥檃v猫nement du g茅nie g茅n茅tique qui deviendra biologie mol茅culaire.</p> <p class="text-align-justify">Avec ces techniques, il s鈥檈ngage ensuite avec l鈥櫭﹒uipe de Danielle Dhouailly 脿 l鈥橧AB pour explorer les voies de signalisation cellulaires impliqu茅es dans le d茅veloppement embryonnaire. Pour cela, il met au point 芦 Flogentec 禄脿 <a href="https://www.biopolis.fr/">Biopolis</a>, un automate permettant d鈥檈ffectuer les analyses d鈥檋ybridation in situ en seulement 22 heures. Flogentec a r茅cemment 茅volu茅 en une entreprise qui a gard茅 ce nom. 芦 TIMC-IMAG est bien l鈥檈ndroit r锚v茅 pour allier biologie et technologie, presque tout est nouveau pour moi 禄 dit-il ravi.</p> <p class="text-align-justify">Jacques travaille 脿 pr茅sent dans l'茅quipe SyNaBi, sur les biopiles implantables, pour lesquelles il d茅veloppe des 茅mulsions stables d鈥檈au dans l鈥檋uile capables de supporter une compression. Son objectif est d鈥檕btenir une tr猫s grande surface d茅velopp茅e de bicouches lipidiques dans lesquelles sont inclues des prot茅ines transmembranaires recombinantes. Ces prot茅ines sont capables d鈥檌nduire une polarisation membranaire mimant l鈥檌nflux nerveux. Un assemblage judicieux de ces 芦 cellules 禄 biomim茅tiques polaris茅es pourra 锚tre 脿 l鈥檕rigine d鈥檜n potentiel exploitable gr芒ce 脿 des 茅lectrodes collectrices.</p> <p class="text-align-justify">聽</p> <p class="text-align-justify">聽</p> </div> </div> </article> </div> </section> </div> </div> <footer role="contentinfo"> <div class="flex-top-first-footer "> <div class="row "> <div class="up container"> <div class="left-side-tit"><h5>Tutelles</h5></div> <div class="right-side-part"><h5>Partenaires</h5></div> </div> </div> <div class="corp container"> <div class=" row"> <div class="flex-set"><a target="_blank" href="http://www.cnrs.fr/"><img src="/themes/timc/images/2.png" alt=""></a></div> <div class="flex-set"><a target="_blank" href="http://www.univ-grenoble-alpes.fr/"><img src="/themes/timc/images/5.png" alt=""></a></div> <div class="flex-set"><a target="_blank" href="http://www.vetagro-sup.fr/"><img src="/themes/timc/images/6.png" alt=""></a></div> <div class="flex-set"><a 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