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Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents - PubMed
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class="collections-new" name="collections" value="new" data-ga-category="save_share" data-ga-action="collections" data-ga-label="collections_radio_new"> <label for="collections-action-panel-new">Create a new collection</label> </li> <li> <input type="radio" id="collections-action-panel-existing" class="collections-existing" name="collections" value="existing" checked="true" data-ga-category="save_share" data-ga-action="collections" data-ga-label="collections_radio_existing"> <label for="collections-action-panel-existing">Add to an existing collection</label> </li> </ul> </div> <div class="controls-wrapper"> <div class="action-panel-control-wrap new-collections-controls"> <label for="collections-action-panel-add-to-new" class="action-panel-label required-field-asterisk"> Name your collection: </label> <input type="text" name="add-to-new-collection" id="collections-action-panel-add-to-new" class="collections-action-add-to-new" pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/" maxlength="100" data-ga-category="save_share" data-ga-action="create_collection" data-ga-label="non_favorties_collection"> <div class="collections-new-name-too-long usa-input-error-message selection-validation-message"> Name must be less than 100 characters </div> </div> <div class="action-panel-control-wrap existing-collections-controls"> <label for="collections-action-panel-add-to-existing" class="action-panel-label"> Choose a collection: </label> <select id="collections-action-panel-add-to-existing" class="action-panel-selector collections-action-add-to-existing" data-ga-category="save_share" data-ga-action="select_collection" data-ga-label="($('#collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"> </select> <div class="collections-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your collection due to an error<br> <a href="#">Please try again</a> </div> </div> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore data-ga-category="save_share" data-ga-action="collections" data-ga-label="add"> Add </button> <button class="action-panel-cancel" aria-label="Close 'Add to Collections' panel" ref="linksrc=close_collections_panel" aria-controls="collections-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="collections" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="bibliography-action-panel" class="bibliography-action-panel action-panel in-progress-dots-panel" aria-hidden="true" data-bibliography-open-panel-enabled="false" data-bibliography-open-panel-url-hash="#open-bibliography-panel"> <div class="inner-wrap"> <h3 class="action-panel-heading"> Add to My Bibliography </h3> <form id="bibliography-action-panel-form" class="bibliography-action-panel-form action-panel-content action-form action-panel-smaller-selectors" data-add-to-bibliography-max-amount="100" data-add-to-bibliography-batch-size="10" data-bibliography-delegates-url="/list-bibliography-delegates/" data-add-to-bibliography-url="/add-to-bibliography/" data-get-article-ids-by-search-url="/get-article-ids-by-search/" data-mybib-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/mybibliography/"> <input type="hidden" name="csrfmiddlewaretoken" value="ieKyWUJMkVToMKjkbHqenLaHOf2hh0OB1Pp0rAp8MNXSyQX3xLZ3gAcR5cC6VMa0"> <div class="action-panel-control-wrap bibliographies-controls"> <div class="choice-group"> <ul class="bibliographies-action-add radio-group-items"> <li> <input name="bibliography" id="my-bibliography" class="my-bibliography" type="radio" checked/> <label for="my-bibliography">My Bibliography</label> </li> </ul> </div> </div> <div class="bibliographies-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your delegates due to an error<br> <a href="#">Please try again</a> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore> Add </button> <button class="action-panel-cancel" aria-label="Close 'Add to bibliography' panel" ref="linksrc=close_bibliography_panel" aria-controls="bibliography-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="mybib" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="saved-search-action-panel" class="saved-search-action-panel action-panel " aria-hidden="true" data-saved-search-open-panel-enabled="false" data-saved-search-open-panel-url-hash="#open-saved-search-panel"> <div class="inner-wrap"> <h2 class="action-panel-heading"> Your saved search </h2> <form id="saved-search-action-panel-form" class="saved-search-action-panel-form action-panel-content action-form" data-create-saved-search-url="/create-saved-search/" data-try-search-terms-url="/try-search-term/" data-saved-search-root-url="https://www.ncbi.nlm.nih.gov/myncbi/searches/"> <input type="hidden" name="csrfmiddlewaretoken" value="ieKyWUJMkVToMKjkbHqenLaHOf2hh0OB1Pp0rAp8MNXSyQX3xLZ3gAcR5cC6VMa0"> <div class="action-panel-control-wrap"> <label for="saved-search-name" class="action-panel-label saved-search-name-label required-field-asterisk"> Name of saved search: </label> <input maxlength="200" type="text" name="saved-search-name" id="saved-search-name" class="saved-search-name" value="" required pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"> </div> <div class="action-panel-control-wrap"> <label for="saved-search-term" class="action-panel-label required-field-asterisk"> Search terms: </label> <textarea name="saved-search-term" id="saved-search-term" class="saved-search-term" required></textarea> </div> <div class="test-search-term-wrap"> <a href="#" class="try-search-term">Test search terms</a> </div> <div class="choice-group action-panel-extra-margin-top"> <span class="action-panel-label" id="fieldset-label"> Would you like email updates of new search results? </span> <fieldset id="saved-search-alert" aria-describedby="fieldset-label"> <legend class="usa-sr-only">Saved Search Alert Radio Buttons</legend> <ul class="radio-group-items"> <li> <input type="radio" id="saved-search-alert-yes" class="saved-search-alert-yes" name="saved-search-alert" value="yes" checked> <label for="saved-search-alert-yes" class="action-panel-label">Yes</label> </li> <li> <input aria-label="No radio input" type="radio" id="saved-search-alert-no" class="saved-search-alert-no" name="saved-search-alert" value="no"> <label for="saved-search-alert-no" class="action-panel-label">No</label> </li> </ul> </fieldset> </div> <div class="alert-schedule-wrap"> <div class="action-panel-control-wrap"> <label class="action-panel-label"> Email: </label> <span aria-label="Email address" id="saved-search-email" class="action-panel-label"><span class="action-panel-label-bold"></span> (<a class="myncbi-account-settings" href="https://www.ncbi.nlm.nih.gov/account/settings/">change</a>)</span> </div> <div class="action-panel-control-wrap action-panel-extra-margin-top"> <label for="saved-search-frequency" class="action-panel-label"> Frequency: </label> <select id="saved-search-frequency" class="no-border-panel-selector saved-search-frequency"> <option value="monthly">Monthly</option> <option value="weekly">Weekly</option> <option value="daily">Daily</option> </select> </div> <div class="action-panel-control-wrap saved-search-monthly-additional"> <label for="saved-search-monthly-on-day" class="action-panel-label"> Which day? </label> <select id="saved-search-monthly-on-day" class="no-border-panel-selector"> <option value="Sunday">The first Sunday</option> <option value="Monday">The first Monday</option> <option value="Tuesday">The first Tuesday</option> <option value="Wednesday">The first Wednesday</option> <option value="Thursday">The first Thursday</option> <option value="Friday">The first Friday</option> <option value="Saturday">The first Saturday</option> <option value="day">The first day</option> <option value="weekday">The first weekday</option> </select> </div> <div class="action-panel-control-wrap saved-search-weekly-additional"> <label for="saved-search-weekly-on-day" class="action-panel-label"> Which day? </label> <select id="saved-search-weekly-on-day" class="no-border-panel-selector saved-search-weekly-on-day"> <option value="Sunday">Sunday</option> <option value="Monday">Monday</option> <option value="Tuesday">Tuesday</option> <option value="Wednesday">Wednesday</option> <option value="Thursday">Thursday</option> <option value="Friday">Friday</option> <option value="Saturday">Saturday</option> </select> </div> <div class="action-panel-control-wrap"> <label for="saved-search-report" class="action-panel-label"> Report format: </label> <select id="saved-search-report" class="no-border-panel-selector saved-search-report"> <option value="DocSum">Summary</option> <option value="DocSumText">Summary (text)</option> <option value="Abstract">Abstract</option> <option value="AbstractText">Abstract (text)</option> <option value="MEDLINE">PubMed</option> </select> </div> <div class="action-panel-control-wrap"> <label for="saved-search-amount" class="action-panel-label"> Send at most: </label> <select id="saved-search-amount" class="no-border-panel-selector saved-search-amount"> <option value="1">1 item</option> <option value="5" selected>5 items</option> <option value="10">10 items</option> <option value="20">20 items</option> <option value="50">50 items</option> <option value="100">100 items</option> <option value="200">200 items</option> </select> </div> <div> <input type="checkbox" id="saved-search-send-if-no-result" class="saved-search-send-if-no-result" name="saved-search-send-if-no-result"> <label for="saved-search-send-if-no-result" class="action-panel-label smaller-checkbox"> Send even when there aren't any new results </label> </div> <div class="action-panel-control-wrap option-text-in-email-wrap"> <label for="saved-search-email-text" class="action-panel-label"> Optional text in email: </label> <textarea name="saved-search-email-text" id="saved-search-email-text" class="saved-search-email-text"></textarea> </div> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Saving..." data-ga-category="save_share" data-ga-action="alert" data-ga-label="save"> Save </button> <button class="action-panel-cancel" aria-label="Close 'Your saved search' panel" ref="linksrc=close_saved_search_panel" aria-controls="saved-search-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="alert" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="citation-manager-action-panel" class="citation-manager-action-panel action-panel" aria-hidden="true"> <div class="inner-wrap"> <h2 class="action-panel-heading"> Create a file for external citation management software </h2> <form id="citation-manager-action-panel-form" class="action-panel-content action-form" action="/results-export-ids/" data-by-search-action="/results-export-search-data/" data-by-ids-action="/results-export-ids/" method="post" data-by-search-method="post" data-by-ids-method="post"> <input type="hidden" name="csrfmiddlewaretoken" value="ieKyWUJMkVToMKjkbHqenLaHOf2hh0OB1Pp0rAp8MNXSyQX3xLZ3gAcR5cC6VMa0"> <input name="results-format" type="hidden" value="pubmed"/> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Sending..." data-ga-category="save_share" data-ga-action="citation_manager" data-ga-label="save"> Create file </button> <button class="action-panel-cancel" aria-label="Close 'Send citations to citation manager' panel" ref="linksrc=close_citation_manager_panel" aria-controls="citation-manager-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="citation_manager" data-ga-label="cancel"> Cancel </button> </div> </form> </div> </div> <div id="rss-action-panel" class="rss-action-panel action-panel " aria-hidden="true"> <div class="inner-wrap"> <h2 class="action-panel-heading"> Your RSS Feed </h2> <form id="rss-action-panel-form" class="rss-action-panel-form action-panel-content action-form" data-create-rss-feed-url="/create-rss-feed-url/" data-search-form-term-value=""> <input type="hidden" name="csrfmiddlewaretoken" value="ieKyWUJMkVToMKjkbHqenLaHOf2hh0OB1Pp0rAp8MNXSyQX3xLZ3gAcR5cC6VMa0"> <div class="action-panel-control-wrap"> <label for="rss-name" class="action-panel-label required-field-asterisk"> Name of RSS Feed: </label> <input maxlength="200" placeholder="Name" type="text" name="rss-name" id="rss-name" class="rss-name" value='' required pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/"> </div> <div class="rss-limit-wrap"> <div class="action-panel-control-wrap action-panel-extra-margin-top"> <label for="rss-limit" class="action-panel-label"> Number of items displayed: </label> <select id="rss-limit" class="no-border-panel-selector rss-limit"> <option value="5">5</option> <option value="10">10</option> <option value="15" selected="selected">15</option> <option value="20">20</option> <option value="50">50</option> <option value="100">100</option> </select> </div> </div> <div class="action-panel-actions"> <button class="action-panel-submit" type="submit" data-loading-label="Creating..." data-ga-category="save_share" data-ga-action="alert" data-ga-label="save"> Create RSS </button> <button class="action-panel-cancel" aria-label="Close 'Your RSS' panel" ref="linksrc=close_rss_panel" aria-controls="rss-action-panel" aria-expanded="false" data-ga-category="save_share" data-ga-action="alert" data-ga-label="cancel"> Cancel </button> </div> <div class="action-panel-control-wrap rss-link-copy-wrap"> <label for="rss-link" class="usa-sr-only">RSS Link</label> <input placeholder="Your RSS Feed Link" type="text" name="rss-link" id="rss-link" class="rss-link" title="RSS Link"> <button type="button" disabled class="rss-link-copy-button disabled" data-ga-category="save_share" data-ga-action="rss" data-ga-label="copy"> Copy </button> </div> </form> </div> </div> </div> </div> <div class="article-page" id="article-page" data-article-pmid="15870416"> <aside class="page-sidebar"> <div class="inner-wrap"> <div class="full-text-links"> <div class="full-view"> <h3 class="title"> Full text links </h3> <div class="full-text-links-list"> <a class="link-item dialog-focus" href="https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.293.17.2126" target="_blank" rel="noopener" ref="linksrc=fulltextorjournal_fulltext&is_pmc=False&PrId=7898&itool=Abstract-def&log$=linkouticon&uid=15870416&db=pubmed&nlmid=7501160" title="See full text options at Silverchair Information Systems" data-ga-category="full_text" data-ga-action="Silverchair Information Systems" data-ga-label="15870416" ><img src="https://cdn.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--jama.jamanetwork.com-images-PUBMED_JAMA_full.gif" alt="Silverchair Information Systems full text link"><span class="text"> Silverchair Information Systems </span></a> </div> </div> <div class="short-view"> <a href="#" class="full-text-links-button full-text-links-dialog-trigger"> Full text links </a> </div> </div> <div class="actions-buttons sidebar"><h3 class="title">Actions</h3><div class="inner-wrap"><button class="citation-button citation-dialog-trigger" aria-label="Open dialog with citation text in different styles" data-ga-category="save_share" data-ga-action="cite" data-ga-label="open" data-all-citations-url="/15870416/citations/" data-citation-style="nlm" data-pubmed-format-link="/15870416/export/"><span class="button-label">Cite</span></button><link type="text/css" href="ncbi-overlay-block/src/overlay-block.css"><div class="collections-button-container" data-article-id="15870416" data-article-db="pubmed"><button class="collections-button collections-dialog-trigger" aria-label="Save article in MyNCBI collections." data-ga-category="collections_button" data-ga-action="click" data-ga-label="collections_button" data-collections-open-dialog-enabled="false" data-collections-open-dialog-url="https://account.ncbi.nlm.nih.gov/?back_url=https%3A%2F%2Fpubmed.ncbi.nlm.nih.gov%2F15870416%2F%23open-collections-dialog" data-in-collections="false"><span class="button-label">Collections</span></button><div class="overlay" role="dialog"><div id="collections-action-dialog" class="dialog collections-dialog" aria-hidden="true"><div class="title">Add to Collections</div><div class="collections-action-panel action-panel"><form id="collections-action-dialog-form" class="collections-action-panel-form action-panel-content action-form action-panel-smaller-selectors" data-existing-collections-url="/list-existing-collections/" data-add-to-existing-collection-url="/add-to-existing-collection/" data-create-and-add-to-new-collection-url="/create-and-add-to-new-collection/" data-myncbi-max-collection-name-length="100" data-collections-root-url="https://www.ncbi.nlm.nih.gov/myncbi/collections/"><input type="hidden" name="csrfmiddlewaretoken" value="ieKyWUJMkVToMKjkbHqenLaHOf2hh0OB1Pp0rAp8MNXSyQX3xLZ3gAcR5cC6VMa0"><div class="choice-group" role="radiogroup"><ul class="radio-group-items"><li><input type="radio" id="collections-action-dialog-new" class="collections-new" name="collections" value="new" data-ga-category="collections_button" data-ga-action="click" data-ga-label="collections_radio_new"><label for="collections-action-dialog-new">Create a new collection</label></li><li><input type="radio" id="collections-action-dialog-existing" class="collections-existing" name="collections" value="existing" checked="true" data-ga-category="collections_button" data-ga-action="click" data-ga-label="collections_radio_existing"><label for="collections-action-dialog-existing">Add to an existing collection</label></li></ul></div><div class="controls-wrapper"><div class="action-panel-control-wrap new-collections-controls"><label for="collections-action-dialog-add-to-new" class="action-panel-label required-field-asterisk"> Name your collection: </label><input type="text" name="add-to-new-collection" id="collections-action-dialog-add-to-new" class="collections-action-add-to-new" pattern="[^"&=<>\/]*" title="The following characters are not allowed in the Name field: "&=<>/" maxlength="100" data-ga-category="collections_button" data-ga-action="create_collection" data-ga-label="non_favorties_collection"><div class="collections-new-name-too-long usa-input-error-message selection-validation-message"> Name must be less than 100 characters </div></div><div class="action-panel-control-wrap existing-collections-controls"><label for="collections-action-dialog-add-to-existing" class="action-panel-label"> Choose a collection: </label><select id="collections-action-dialog-add-to-existing" class="action-panel-selector collections-action-add-to-existing" data-ga-category="collections_button" data-ga-action="select_collection" data-ga-label="($('.collections-action-add-to-existing').val() === 'Favorites') ? 'Favorites' : 'non_favorites_collection'"></select><div class="collections-retry-load-on-error usa-input-error-message selection-validation-message"> Unable to load your collection due to an error<br><a href="#">Please try again</a></div></div></div><div class="action-panel-actions"><button class="action-panel-submit" type="submit" data-loading-label="Adding..." data-pinger-ignore data-ga-category="collections_button" data-ga-action="click" data-ga-label="add"> Add </button><button class="action-panel-cancel" aria-label="Close 'Add to Collections' panel" ref="linksrc=close_collections_panel" aria-controls="collections-action-panel" aria-expanded="false" data-ga-category="collections_button" data-ga-action="click" data-ga-label="cancel"> Cancel </button></div></form></div></div></div></div><button class="more-actions-button more-actions-dialog-trigger" title="Open dialog with more actions to take" ref="linksrc=more_actions_btn"></button><div class="display-options" 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</select> </nav> </div> </aside> <main class="article-details" id="article-details"> <!-- "Filters applied" shows only when page is redirected from search --> <!-- because search found one result --> <header class="heading" id="heading"> <div class="full-view" id="full-view-heading"> <div class="article-citation"> <div class="publication-type" >Multicenter Study</div> <div class="article-source"> <div class="journal-actions dropdown-block"><button id="full-view-journal-trigger" class="journal-actions-trigger trigger" ref="linksrc=journal_actions_btn" title="JAMA" tabindex="0" aria-controls="full-view-journal" aria-expanded="false" aria-label="Toggle dropdown menu for journal JAMA" data-pinger-ignore> JAMA </button><div id="full-view-journal" class="journal-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for journal JAMA"><div class="title">Actions</div><div class="content"><ul class="journal-actions-links"><li><a class="search-in-pubmed-link 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class="citation-doi"> doi: 10.1001/jama.293.17.2126. </span> </div> <h1 class="heading-title"> Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents </h1> <div class="inline-authors"> <div class="authors"> <div class="authors-list"> <span class="authors-list-item "><a class="full-name" href="/?term=Iakovou+I&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Ioannis Iakovou">Ioannis Iakovou</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" title="Centro Cuore Columbus and San Raffaele Hospital, Milan, Italy." href="#full-view-affiliation-1" ref="linksrc=author_aff"> 1 </a></sup><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Schmidt+T&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Thomas Schmidt">Thomas Schmidt</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Bonizzoni+E&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Erminio Bonizzoni">Erminio Bonizzoni</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Ge+L&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Lei Ge">Lei Ge</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Sangiorgi+GM&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Giuseppe M Sangiorgi">Giuseppe M Sangiorgi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Stankovic+G&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Goran Stankovic">Goran Stankovic</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Airoldi+F&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Flavio Airoldi">Flavio Airoldi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Chieffo+A&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Alaide Chieffo">Alaide Chieffo</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Montorfano+M&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Matteo Montorfano">Matteo Montorfano</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Carlino+M&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Mauro Carlino">Mauro Carlino</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Michev+I&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Iassen Michev">Iassen Michev</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Corvaja+N&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Nicola Corvaja">Nicola Corvaja</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Briguori+C&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Carlo Briguori">Carlo Briguori</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Gerckens+U&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Ulrich Gerckens">Ulrich Gerckens</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Grube+E&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Eberhard Grube">Eberhard Grube</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Colombo+A&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Antonio Colombo">Antonio Colombo</a></span> </div> </div> </div> <div class="short-article-details"> Affiliations <button class="more-details" id="toggle-authors" 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ref="linksrc=article_id_link&article_id=10.1001/jama.293.17.2126&id_type=DOI" href="https://doi.org/10.1001/jama.293.17.2126" data-ga-category="full_text" data-ga-action="DOI" > 10.1001/jama.293.17.2126 </a> </span> </li> </ul> <div class="in-clipboard-label " hidden> Item in Clipboard </div> </div> <div class="short-view" id="short-view-heading"> <div class="publication-type" >Multicenter Study</div> <h1 class="heading-title"> Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents </h1> <div class="short-citation"> <span class="authors-list"> <span class="authors-list-item "><span class="full-name">Ioannis Iakovou</span><span class="citation-separator"> et al.</span></span> </span> <span class="citation-journal"> JAMA<span class="citation-separator">.</span> </span> <span class="date"> <time class="citation-year" datetime="2005">2005</time><span class="citation-separator">.</span> </span> </div> <div class="more-article-details-section 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class="authors"> <h3 class="title"> Authors </h3> <div class="authors-list"> <span class="authors-list-item "><a class="full-name" href="/?term=Iakovou+I&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Ioannis Iakovou">Ioannis Iakovou</a><sup class="affiliation-links"><span class="author-sup-separator"> </span><a class="affiliation-link" title="Centro Cuore Columbus and San Raffaele Hospital, Milan, Italy." href="#short-view-affiliation-1" ref="linksrc=author_aff"> 1 </a></sup><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Schmidt+T&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Thomas Schmidt">Thomas Schmidt</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Bonizzoni+E&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Erminio Bonizzoni">Erminio Bonizzoni</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Ge+L&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Lei Ge">Lei Ge</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Sangiorgi+GM&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Giuseppe M Sangiorgi">Giuseppe M Sangiorgi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Stankovic+G&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Goran Stankovic">Goran Stankovic</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Airoldi+F&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Flavio Airoldi">Flavio Airoldi</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Chieffo+A&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Alaide Chieffo">Alaide Chieffo</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Montorfano+M&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Matteo Montorfano">Matteo Montorfano</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Carlino+M&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Mauro Carlino">Mauro Carlino</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Michev+I&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Iassen Michev">Iassen Michev</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Corvaja+N&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Nicola Corvaja">Nicola Corvaja</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Briguori+C&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Carlo Briguori">Carlo Briguori</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Gerckens+U&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Ulrich Gerckens">Ulrich Gerckens</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Grube+E&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Eberhard Grube">Eberhard Grube</a><span class="comma">, </span></span><span class="authors-list-item "><a class="full-name" href="/?term=Colombo+A&cauthor_id=15870416" ref="linksrc=author_name_link" data-ga-category="search" data-ga-action="author_link" data-ga-label="Antonio Colombo">Antonio Colombo</a></span> </div> </div> <div class="affiliations"> <h3 class="title"> Affiliation </h3> <ul class="item-list"> <li data-affiliation-id="short-view-affiliation-1" id="short-view-affiliation-1" ><sup class="key">1</sup> Centro Cuore Columbus and San Raffaele Hospital, Milan, Italy.</li> </ul> </div> </div> <ul class="identifiers" id="short-view-identifiers"> <li> <span class="identifier pubmed"> <span class="id-label"> PMID: </span> <strong class="current-id" title="PubMed ID">15870416</strong> </span> </li> <li> <span class="identifier doi"> <span class="id-label"> DOI: </span> <a class="id-link" target="_blank" rel="noopener" ref="linksrc=article_id_link&article_id=10.1001/jama.293.17.2126&id_type=DOI" href="https://doi.org/10.1001/jama.293.17.2126" data-ga-category="full_text" data-ga-action="DOI" > 10.1001/jama.293.17.2126 </a> </span> </li> </ul> <div class="in-clipboard-label " hidden> Item in Clipboard </div> </div> </div> </header> <div class="actions-buttons inline"><div class="inner-wrap"><button class="full-text-links-button full-text-links-dialog-trigger" title="Open dialog with full text links" ref="linksrc=full_text_links"> Full text links </button><button class="citation-button citation-dialog-trigger" aria-label="Open dialog with citation text in different styles" data-ga-category="save_share" data-ga-action="cite" data-ga-label="open" data-all-citations-url="/15870416/citations/" data-citation-style="nlm" data-pubmed-format-link="/15870416/export/"><span class="button-label">Cite</span></button><button class="more-actions-button more-actions-dialog-trigger" title="Open dialog with more actions to take" ref="linksrc=more_actions_btn"></button><div class="display-options" data-format-key="format" data-default-format-value="abstract" data-current-format-value="abstract" role="region"><button class="trigger usa-button" title="Change format" data-ga-category="display_options" data-ga-action="display_options_dialog"><span class="button-label">Display options</span></button><div class="dropdown" hidden><div class="title"> Display options </div><div class="content"><div class="format-container"><span class="option-label"> Format </span><select name="format" data-initial-value="abstract" aria-label="Display format" id="inline-actions-display-format"><option value="abstract">Abstract</option><option value="pubmed">PubMed</option><option value="pmid">PMID</option></select></div></div></div></div></div></div> <div class="abstract" id="abstract"> <h2 class="title"> Abstract </h2> <div class="abstract-content selected" id="eng-abstract"> <p> <strong class="sub-title"> Context: </strong> Traditionally, stent thrombosis has been regarded as a complication of percutaneous coronary interventions during the first 30 postprocedural days. However, delayed endothelialization associated with the implantation of drug-eluting stents may extend the risk of thrombosis beyond 30 days. Data are limited regarding the risks and the impact of this phenomenon outside clinical trials. </p> <p> <strong class="sub-title"> Objective: </strong> To evaluate the incidence, predictors, and clinical outcome of stent thrombosis after implantation of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice. </p> <p> <strong class="sub-title"> Design, setting, and patients: </strong> Prospective observational cohort study conducted at 1 academic hospital and 2 community hospitals in Germany and Italy. A total of 2229 consecutive patients underwent successful implantation of sirolimus-eluting (1062 patients, 1996 lesions, 2272 stents) or paclitaxel-eluting (1167 patients, 1801 lesions, 2223 stents) stents between April 2002 and January 2004. </p> <p> <strong class="sub-title"> Interventions: </strong> Implantation of a drug-eluting stent (sirolimus or paclitaxel). All patients were pretreated with ticlopidine or clopidogrel and aspirin. Aspirin was continued indefinitely and clopidogrel or ticlopidine for at least 3 months after sirolimus-eluting and for at least 6 months after paclitaxel-eluting stent implantation. </p> <p> <strong class="sub-title"> Main outcome measures: </strong> Subacute thrombosis (from procedure end through 30 days), late thrombosis (>30 days), and cumulative stent thrombosis. </p> <p> <strong class="sub-title"> Results: </strong> At 9-month follow-up, 29 patients (1.3%) had stent thrombosis (9 [0.8%] with sirolimus and 20 [1.7%] with paclitaxel; P = .09). Fourteen patients had subacute thrombosis (0.6%) and 15 patients had late thrombosis (0.7%). Among these 29 patients, 13 died (case fatality rate, 45%). Independent predictors of stent thrombosis were premature antiplatelet therapy discontinuation (hazard ratio [HR], 89.78; 95% CI, 29.90-269.60; P<.001), renal failure (HR, 6.49; 95% CI, 2.60-16.15; P<.001), bifurcation lesions (HR, 6.42; 95% CI, 2.93-14.07; P<.001), diabetes (HR, 3.71; 95% CI, 1.74-7.89; P = .001), and a lower ejection fraction (HR, 1.09; 95% CI, 1.05-1.36; P<.001 for each 10% decrease). </p> <p> <strong class="sub-title"> Conclusions: </strong> The cumulative incidence of stent thrombosis 9 months after successful drug-eluting stent implantation in consecutive "real-world" patients was substantially higher than the rate reported in clinical trials. Premature antiplatelet therapy discontinuation, renal failure, bifurcation lesions, diabetes, and low ejection fraction were identified as predictors of thrombotic events. </p> </div> </div> <p class="disclaimer" id="disclaimer"> <a href="/disclaimer/" target="_blank" data-ga-category="literature_resources" data-ga-action="disclaimer_link" data-ga-label="under_abstract">PubMed Disclaimer</a> </p> <div class="linked-articles" id="linked-commentary"> <h2 class="title"> Comment in </h2> <ul class="item-list usa-unstyled-list"> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/15870421/" ref="article_id=15870421&linksrc=comments_link" data-ga-category="comment_correction" data-ga-action="abstract_page_link" data-ga-label="linked-commentary"> Drug-eluting stents in acute myocardial infarction: is science catching up with practice? </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Cohen MG, Ohman EM.</span> <span class="docsum-authors short-authors">Cohen MG, et al.</span> <span class="docsum-journal-citation full-journal-citation">JAMA. 2005 May 4;293(17):2154-6. doi: 10.1001/jama.293.17.2154.</span> <span class="docsum-journal-citation short-journal-citation">JAMA. 2005.</span> <span class="citation-part">PMID: <span class="docsum-pmid">15870421</span></span> <span class="no-abstract spaced-citation-item citation-part">No abstract available.</span> </div> </div> </li> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/16391212/" ref="article_id=16391212&linksrc=comments_link" data-ga-category="comment_correction" data-ga-action="abstract_page_link" data-ga-label="linked-commentary"> Thrombosis after implantation of drug-eluting stents. </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Marret E, Collet JP, Albaladejo P, Montalescot G.</span> <span class="docsum-authors short-authors">Marret E, et al.</span> <span class="docsum-journal-citation full-journal-citation">JAMA. 2006 Jan 4;295(1):36; author reply 36. doi: 10.1001/jama.295.1.36-a.</span> <span class="docsum-journal-citation short-journal-citation">JAMA. 2006.</span> <span class="citation-part">PMID: <span class="docsum-pmid">16391212</span></span> <span class="no-abstract spaced-citation-item citation-part">No abstract available.</span> </div> </div> </li> </ul> </div> <div class="similar-articles" id="similar"> <h2 class="title"> Similar articles </h2> <ul class="articles-list" id="similar-articles-list"> <li class="full-docsum"> <div class="docsum-content" style="display:inline;"> <a class="docsum-title" href="/17572245/" ref="article_id=17572245&linksrc=similar_articles_link&ordinalpos=1" data-ga-category="similar_article" data-ga-action="17572245" data-ga-label=""> Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. </a> <div class="docsum-citation full-citation"> <span class="docsum-authors full-authors">Buonamici P, Marcucci R, Migliorini A, Gensini GF, Santini A, Paniccia R, Moschi G, Gori AM, Abbate R, Antoniucci D.</span> <span class="docsum-authors short-authors">Buonamici P, et al.</span> <span class="docsum-journal-citation full-journal-citation">J Am Coll Cardiol. 2007 Jun 19;49(24):2312-7. doi: 10.1016/j.jacc.2007.01.094. 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class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Incidence"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Incidence"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Male" tabindex="0" aria-controls="keyword-actions-mesh-terms-5" aria-expanded="false" data-pinger-ignore> Male </button><div id="keyword-actions-mesh-terms-5" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Male"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Male%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Male%22%5BMeSH%5D&sort=date&sort_order=desc" 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data-search-term=""Middle Aged"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Middle Aged"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Myocardial Infarction / therapy" tabindex="0" aria-controls="keyword-actions-mesh-terms-7" aria-expanded="false" data-pinger-ignore> Myocardial Infarction / therapy </button><div id="keyword-actions-mesh-terms-7" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Myocardial Infarction / therapy"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Myocardial+Infarction%2Ftherapy%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Myocardial+Infarction%2Ftherapy%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Myocardial Infarction/therapy"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Myocardial Infarction / therapy"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Myocardial+Infarction" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Myocardial Infarction / therapy"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Myocardial Infarction/therapy"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Myocardial Infarction/therapy"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major" aria-label="Toggle dropdown menu for keyword Paclitaxel / administration & dosage*" tabindex="0" aria-controls="keyword-actions-mesh-terms-major-8" aria-expanded="false" data-pinger-ignore> Paclitaxel / administration & dosage* </button><div id="keyword-actions-mesh-terms-major-8" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Paclitaxel / administration & dosage*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Paclitaxel%2Fadministration+and+dosage%22%5BMAJR%5D&sort=date&sort_order=desc" data-href="/?term=%22Paclitaxel%2Fadministration+and+dosage%22%5BMAJR%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Paclitaxel/administration and dosage"[MAJR]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Paclitaxel / administration & dosage*"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Paclitaxel" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Paclitaxel / administration & dosage*"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Paclitaxel/administration and dosage"[MAJR]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Paclitaxel/administration and dosage"[MAJR]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Prospective Studies" tabindex="0" aria-controls="keyword-actions-mesh-terms-9" aria-expanded="false" data-pinger-ignore> Prospective Studies </button><div id="keyword-actions-mesh-terms-9" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Prospective Studies"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Prospective+Studies%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Prospective+Studies%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Prospective Studies"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Prospective Studies"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Prospective+Studies" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Prospective Studies"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Prospective Studies"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Prospective Studies"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Risk" tabindex="0" aria-controls="keyword-actions-mesh-terms-10" aria-expanded="false" data-pinger-ignore> Risk </button><div id="keyword-actions-mesh-terms-10" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Risk"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Risk%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Risk%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Risk"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Risk"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Risk" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Risk"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Risk"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Risk"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major" aria-label="Toggle dropdown menu for keyword Sirolimus / administration & dosage*" tabindex="0" aria-controls="keyword-actions-mesh-terms-major-11" aria-expanded="false" data-pinger-ignore> Sirolimus / administration & dosage* </button><div id="keyword-actions-mesh-terms-major-11" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Sirolimus / administration & dosage*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Sirolimus%2Fadministration+and+dosage%22%5BMAJR%5D&sort=date&sort_order=desc" data-href="/?term=%22Sirolimus%2Fadministration+and+dosage%22%5BMAJR%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Sirolimus/administration and dosage"[MAJR]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Sirolimus / administration & dosage*"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Sirolimus" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Sirolimus / administration & dosage*"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Sirolimus/administration and dosage"[MAJR]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Sirolimus/administration and dosage"[MAJR]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major" aria-label="Toggle dropdown menu for keyword Stents*" tabindex="0" aria-controls="keyword-actions-mesh-terms-major-12" aria-expanded="false" data-pinger-ignore> Stents* </button><div id="keyword-actions-mesh-terms-major-12" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Stents*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Stents%22%5BMAJR%5D&sort=date&sort_order=desc" data-href="/?term=%22Stents%22%5BMAJR%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Stents"[MAJR]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Stents*"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Stents" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Stents*"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Stents"[MAJR]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Stents"[MAJR]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link major" aria-label="Toggle dropdown menu for keyword Thrombosis / epidemiology*" tabindex="0" aria-controls="keyword-actions-mesh-terms-major-13" aria-expanded="false" data-pinger-ignore> Thrombosis / epidemiology* </button><div id="keyword-actions-mesh-terms-major-13" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Thrombosis / epidemiology*"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Thrombosis%2Fepidemiology%22%5BMAJR%5D&sort=date&sort_order=desc" data-href="/?term=%22Thrombosis%2Fepidemiology%22%5BMAJR%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Thrombosis/epidemiology"[MAJR]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Thrombosis / epidemiology*"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Thrombosis" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Thrombosis / epidemiology*"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Thrombosis/epidemiology"[MAJR]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Thrombosis/epidemiology"[MAJR]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Thrombosis / etiology" tabindex="0" aria-controls="keyword-actions-mesh-terms-14" aria-expanded="false" data-pinger-ignore> Thrombosis / etiology </button><div id="keyword-actions-mesh-terms-14" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Thrombosis / etiology"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Thrombosis%2Fetiology%22%5BMeSH%5D&sort=date&sort_order=desc" data-href="/?term=%22Thrombosis%2Fetiology%22%5BMeSH%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&mesh="Thrombosis/etiology"[MeSH]" data-ga-category="search" data-ga-action="mesh_term" data-ga-label="Thrombosis / etiology"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=Thrombosis" data-ga-category="search_mesh" data-ga-action="mesh_term_link" data-ga-label="Thrombosis / etiology"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Thrombosis/etiology"[MeSH]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Thrombosis/etiology"[MeSH]" href="#"> Add to Search </a></li></ul></div></div></div></li></ul> </div> <div id="substances" class="substances keywords-section"> <h2 class="title"> Substances </h2> <ul class="keywords-list"><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Paclitaxel" tabindex="0" aria-controls="keyword-actions-substances-0" aria-expanded="false" data-pinger-ignore> Paclitaxel </button><div id="keyword-actions-substances-0" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Paclitaxel"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Paclitaxel%22%5Bnm%5D&sort=date&sort_order=desc" data-href="/?term=%22Paclitaxel%22%5Bnm%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&keyword="Paclitaxel"[nm]" data-ga-category="search" data-ga-action="substance" data-ga-label="Paclitaxel"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Paclitaxel%22" data-ga-category="search_mesh" data-ga-action="substance_link" data-ga-label="Paclitaxel"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Paclitaxel"[nm]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Paclitaxel"[nm]" href="#"> Add to Search </a></li></ul></div></div></div></li><li><div class="keyword-actions dropdown-block"><button class="keyword-actions-trigger trigger keyword-link" aria-label="Toggle dropdown menu for keyword Sirolimus" tabindex="0" aria-controls="keyword-actions-substances-1" aria-expanded="false" data-pinger-ignore> Sirolimus </button><div id="keyword-actions-substances-1" class="keyword-actions-dropdown dropdown dropdown-container" hidden aria-label="Dropdown menu for keyword Sirolimus"><div class="title">Actions</div><div class="content"><ul class="keyword-actions-links"><li><a class="search-in-pubmed-link dropdown-block-link" href="/?term=%22Sirolimus%22%5Bnm%5D&sort=date&sort_order=desc" data-href="/?term=%22Sirolimus%22%5Bnm%5D&sort=date&sort_order=desc" ref="linksrc=search_in_pubmed_keyword_link&keyword="Sirolimus"[nm]" data-ga-category="search" data-ga-action="substance" data-ga-label="Sirolimus"> Search in PubMed </a></li><li><a class="search-in-mesh-link dropdown-block-link" ref="linksrc=search_in_mesh_link" href="https://www.ncbi.nlm.nih.gov/mesh?term=%22Sirolimus%22" data-ga-category="search_mesh" data-ga-action="substance_link" data-ga-label="Sirolimus"> Search in MeSH </a></li><li><a class="add-to-search-link dropdown-block-link" ref="linksrc=add_to_search_link" role="button" data-search-term=""Sirolimus"[nm]" data-ga-category="search" data-ga-action="add_to_search" data-ga-label=""Sirolimus"[nm]" href="#"> Add to Search </a></li></ul></div></div></div></li></ul> </div> <div id="related-links" class="related-links"> <h2 class="title"> Related information </h2> <ul class="related-links-list"><li><a title="PubMed links associated with Books" href="https://www.ncbi.nlm.nih.gov/books?linkname=pubmed_books_refs&from_uid=15870416" ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=15870416&ordinalpos=1&linkpos=1"> Cited in Books </a></li><li><a title="Related PubChem Compound" href="https://www.ncbi.nlm.nih.gov/pccompound?linkname=pubmed_pccompound&from_uid=15870416" ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=15870416&ordinalpos=1&linkpos=2"> PubChem Compound </a></li><li><a title="Related PubChem Compound via MeSH" href="https://www.ncbi.nlm.nih.gov/pccompound?linkname=pubmed_pccompound_mesh&from_uid=15870416" ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=15870416&ordinalpos=1&linkpos=3"> PubChem Compound (MeSH Keyword) </a></li><li><a title="Related PubChem Substance" href="https://www.ncbi.nlm.nih.gov/pcsubstance?linkname=pubmed_pcsubstance&from_uid=15870416" ref="log$=recordlinks&logdbfrom=pubmed&ncbi_uid=15870416&ordinalpos=1&linkpos=4"> PubChem Substance </a></li></ul> </div> <div id="linkout" class="linkout"> <h2 class="title"> LinkOut - more resources </h2> <ul class="linkout-list"><li><h3 class="linkout-category">Full Text Sources</h3><ul class="linkout-category-links"><li><a href="http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=15870416.ui" target="_blank" rel="noopener" ref="linksrc=linkout_link&PrId=3682&uid=15870416&db=pubmed&itool=Abstract&log$=linkoutlink&nlmid=7501160" data-ga-category="link_out" data-ga-action="Full Text Sources" data-ga-label="Ovid Technologies, Inc." > Ovid Technologies, Inc. </a></li><li><a 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