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cyclodextrin carriers HP-α-CD, HP-β-CD and HP-γ-CD (2–hydroxypropyl-α, β, γ-cyclodextrin) in a suitable environment for the cultivation of cancerous cell lines, and to determine the optimal radioactive conditions for maximizing photodynamic effects in cancerous cells.","author":[{"@context":"https://schema.org","@type":"Person","name":"Jiří Mosinger"}],"contributor":[],"dateCreated":"2022-07-14","dateModified":"2022-07-14","datePublished":"2004-01-01","headline":"Spectral Characteristics of the Supramolecular Complexes of Polypyrrolic Sensitizers and Cyclodextrin Carriers: Usage in Photodynamic Therapy of Tumors","inLanguage":"en","keywords":["Chemistry","Photochemistry","Polymers","Porphyrins","Medicine","Photodynamic Therapy","Spectrophotometry","Photochemotherapy","Neoplasms","Cyclodextrins","Drug Carriers","Medical and Health Sciences"],"locationCreated":null,"publication":"Acta Medica (Hradec Kralove, Czech 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(2–hydroxypropyl-α, β, γ-cyclodextrin) in a suitable environment for the cultivation of cancerous cell lines, and to determine the optimal radioactive conditions for maximizing photodynamic effects in cancerous cells.","publisher":"Charles University in Prague, Karolinum Press","publication_date":"2004,,","publication_name":"Acta Medica (Hradec Kralove, Czech Republic)"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Spectral Characteristics of the Supramolecular Complexes of Polypyrrolic Sensitizers and Cyclodextrin Carriers: Usage in Photodynamic Therapy of Tumors","broadcastable":false,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [35746871]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "full_page_mobile_sutd_modal"; 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src="//a.academia-assets.com/images/s65_no_pic.png" />Jiří Mosinger</a></div><p class="ds-work-card--detail ds2-5-body-sm">2004, Acta Medica (Hradec Kralove, Czech Republic)</p><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">The objective of our work was to describe the photophysical properties (absorption and fluorescence) of the sensitizers TPPS4, ZnTPPS4 a PdTPPS4 and above all the complexes of these sensitizers with cyclodextrin carriers HP-α-CD, HP-β-CD and HP-γ-CD (2–hydroxypropyl-α, β, γ-cyclodextrin) in a suitable environment for the cultivation of cancerous cell lines, and to determine the optimal radioactive conditions for maximizing photodynamic effects in cancerous cells.</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" 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data-landing_url="https://www.academia.edu/83138806/Spectral_Characteristics_of_the_Supramolecular_Complexes_of_Polypyrrolic_Sensitizers_and_Cyclodextrin_Carriers_Usage_in_Photodynamic_Therapy_of_Tumors" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="92191202" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/92191202/Photophysical_properties_and_photodynamic_activity_in_vivo_of_some_tetrapyrroles">Photophysical properties and photodynamic activity in vivo of some tetrapyrroles</a><div class="ds-related-work--metadata"><a 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href="https://www.academia.edu/15455428/Absorption_Spectra_of_the_Potential_Photodynamic_Therapy_Photosensitizers_Texaphyrins_Complexes_A_Theoretical_Analysis_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="86945357" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/86945357/A_Comparative_Study_of_Photobiological_and_Photophysical_Characteristic_of_Meso_Tetraphenylporphyrin_and_Meso_Tetraphenylchlorin_as_Photosensitizers_for_Photodynamic_Therapy">A Comparative Study of Photobiological and Photophysical Characteristic of Meso-Tetraphenylporphyrin and Meso-Tetraphenylchlorin as Photosensitizers for Photodynamic Therapy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="77425375" href="https://independent.academia.edu/ADjaliasrin">Asmiyenti Djaliasrin</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Science and Technology Indonesia</p><p class="ds-related-work--abstract ds2-5-body-sm">Photosensitizer modifications are needed to improve the performance of Photodynamic Therapy (PDT) for the treatment of cancer. This work appraised the photophysical and photobiological characteristics of tetrapyrrolic macrocycles. Meso-tetraphenylporphyrin (m-TPP) and meso-tetraphenylchlorin (m-TPC) represent non-reduced and reduced pyrrole rings tetrapyrrolic macrocycles, respectively. The absorption spectra of m-TPP and m-TPC were performed. The relative quantum yield of singlet oxygen (ΦΔ) was measured at two different pH (6.3 and 7.4) relative to chlorine e6. Dark toxicity was monitored using the MTT assay on breast cancer T47D and NIH 3T3 cell lines. In addition, the stability of the compounds under indirect sunlight was also observed. The absorption maxima of the Q1 band of both compounds are at a longer wavelength. The Q1 peak of a reduced pyrrole ring is more intense than the non-reduced pyrrole ring with the lowest energy transition undergoing a redshift. The singlet oxygen...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"A Comparative Study of Photobiological and Photophysical Characteristic of Meso-Tetraphenylporphyrin and Meso-Tetraphenylchlorin as Photosensitizers for Photodynamic Therapy","attachmentId":91288334,"attachmentType":"pdf","work_url":"https://www.academia.edu/86945357/A_Comparative_Study_of_Photobiological_and_Photophysical_Characteristic_of_Meso_Tetraphenylporphyrin_and_Meso_Tetraphenylchlorin_as_Photosensitizers_for_Photodynamic_Therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" 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class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/16509566/In_vitro_toxicity_testing_of_supramolecular_sensitizers_for_photodynamic_therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="16509551" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/16509551/Supramolecular_sensitizer_complexation_of_meso_tetrakis_4_sulfonatophenyl_porphyrin_with_2_hydroxypropyl_cyclodextrins">Supramolecular sensitizer: complexation of meso-tetrakis(4-sulfonatophenyl)porphyrin with 2-hydroxypropyl-cyclodextrins</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35746871" href="https://cuni.academia.edu/Ji%C5%99%C3%ADMosinger">Jiří Mosinger</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Photochemistry and Photobiology A: Chemistry, 2000</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Supramolecular sensitizer: complexation of meso-tetrakis(4-sulfonatophenyl)porphyrin with 2-hydroxypropyl-cyclodextrins","attachmentId":42454953,"attachmentType":"pdf","work_url":"https://www.academia.edu/16509551/Supramolecular_sensitizer_complexation_of_meso_tetrakis_4_sulfonatophenyl_porphyrin_with_2_hydroxypropyl_cyclodextrins","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/16509551/Supramolecular_sensitizer_complexation_of_meso_tetrakis_4_sulfonatophenyl_porphyrin_with_2_hydroxypropyl_cyclodextrins"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="83138812" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/83138812/The_Cellular_Uptake_of_Sensitizers_Bound_to_Cyclodextrin_Carriers">The Cellular Uptake of Sensitizers Bound to Cyclodextrin Carriers</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="35746871" href="https://cuni.academia.edu/Ji%C5%99%C3%ADMosinger">Jiří Mosinger</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Acta Medica (Hradec Kralove, Czech Republic), 2004</p><p class="ds-related-work--abstract ds2-5-body-sm">Photodynamic therapy of cancer uses the interaction of sensitizers and light to destroy cancer cells. In this study we tested the cellular uptake of meso-tetrakis(4-sulfonatophenyl)porphine (TPPS4) and its complex PdTPPS4 in the presence or absence of 2–hydroxypropyl-cyclodextrins (hpCDs) on G361 human melanoma cells. Self-fluorescence in G361 cells were measured by Perkin-Elmer LS50B luminometer equipped with well plate reader accessory. Morphological changes in cells have been evaluated using inversion fluorescent microscope Olympus IX 70 and image analysis. The uptake of the sensitizer PdTPPS4 at the given time interval from 1 to 48 hours is markedly higher than the uptake of TPPS4. The highest uptake was found for sensitizer PdTPPS4 in combination with hpβCD. TPPS4 and PdTPPS4 especially in the supramolecular complex with nontoxic cyclodextrin carriers represent efficient sensitizers for photodynamic therapy in vitro on G361 cells.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"The Cellular Uptake of Sensitizers Bound to Cyclodextrin Carriers","attachmentId":88590729,"attachmentType":"pdf","work_url":"https://www.academia.edu/83138812/The_Cellular_Uptake_of_Sensitizers_Bound_to_Cyclodextrin_Carriers","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/83138812/The_Cellular_Uptake_of_Sensitizers_Bound_to_Cyclodextrin_Carriers"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="84586982" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/84586982/Unraveling_the_Photodynamic_Activity_of_Cationic_Benzoporphyrin_Based_Photosensitizers_against_Bladder_Cancer_Cells">Unraveling the Photodynamic Activity of Cationic Benzoporphyrin-Based Photosensitizers against Bladder Cancer Cells</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="42270123" href="https://independent.academia.edu/MGra%C3%A7aPmsNeves">M. Graça P.m.s. Neves</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Molecules</p><p class="ds-related-work--abstract ds2-5-body-sm">In this study, we report the preparation of new mono-charged benzoporphyrin complexes by reaction of the appropriate neutral benzoporphyrin with (2,2′-bipyridine)dichloroplatinum(II) and of the analogs’ derivatives synthesized through alkylation of the neutral scaffold with iodomethane. All derivatives were incorporated into polyvinylpyrrolidone (PVP) micelles. The ability of the resultant formulations to generate reactive oxygen species was evaluated, mainly the singlet oxygen formation. Then, the capability of the PVP formulations to act as photosensitizers against bladder cancer cells was assessed. Some of the studied formulations were the most active photosensitizers causing a decrease in HT-1376 cells’ viability. This creates an avenue to further studies related to bladder cancer cells.</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Unraveling the Photodynamic Activity of Cationic Benzoporphyrin-Based Photosensitizers against Bladder Cancer Cells","attachmentId":89557267,"attachmentType":"pdf","work_url":"https://www.academia.edu/84586982/Unraveling_the_Photodynamic_Activity_of_Cationic_Benzoporphyrin_Based_Photosensitizers_against_Bladder_Cancer_Cells","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/84586982/Unraveling_the_Photodynamic_Activity_of_Cationic_Benzoporphyrin_Based_Photosensitizers_against_Bladder_Cancer_Cells"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="23114825" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23114825/Potential_photosensitizers_for_photodynamic_therapy">Potential photosensitizers for photodynamic therapy</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="44888939" href="https://independent.academia.edu/FMontforts">F. Montforts</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Photochemistry and Photobiology B: Biology, 1994</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Potential photosensitizers for photodynamic therapy","attachmentId":43610845,"attachmentType":"pdf","work_url":"https://www.academia.edu/23114825/Potential_photosensitizers_for_photodynamic_therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/23114825/Potential_photosensitizers_for_photodynamic_therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="21576619" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/21576619/Possible_in_vivo_mechanisms_involved_in_photodynamic_therapy_using_tetrapyrrolic_macrocycles">Possible in vivo mechanisms involved in photodynamic therapy using tetrapyrrolic macrocycles</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="42705153" href="https://independent.academia.edu/SimonaClichici">Simona Clichici</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.]</p><p class="ds-related-work--abstract ds2-5-body-sm">Photodynamic therapy (PDT) mediated by oxidative stress causes direct tumor cell damage as well as microvascular injury. To improve this treatment new photosensitizers are being synthesized and tested. We evaluated the effects of PDT with 5,10,15,20-tetrakis(4-methoxyphenyl)-porphyrin (TMPP) and its zinc complex (ZnTMPP) on tumor levels of malondialdehyde (MDA), reduced glutathione (GSH) and cytokines, and on the activity of caspase-3 and metalloproteases (MMP-2 and -9) and attempted to correlate them with the histological alterations of tumors in 3-month-old male Wistar rats, 180 ± 20 g, bearing Walker 256 carcinosarcoma. Rats were randomly divided into five groups: group 1, ZnTMPP+irradiation (IR) 10 mg/kg body weight; group 2, TMPP+IR 10 mg/kg body weight; group 3, 5-aminolevulinic acid (5-ALA+IR) 250 mg/kg body weight; group 4, control, no treatment; group 5, only IR. The tumors were irradiated for 15 min with red light (100 J/cm², 10 kHz, 685 nm) 24 h after drug administration....</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Possible in vivo mechanisms involved in photodynamic therapy using tetrapyrrolic macrocycles","attachmentId":42116873,"attachmentType":"pdf","work_url":"https://www.academia.edu/21576619/Possible_in_vivo_mechanisms_involved_in_photodynamic_therapy_using_tetrapyrrolic_macrocycles","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/21576619/Possible_in_vivo_mechanisms_involved_in_photodynamic_therapy_using_tetrapyrrolic_macrocycles"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="62567589" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/62567589/Use_of_Cyclodextrins_in_Anticancer_Photodynamic_Therapy_Treatment">Use of Cyclodextrins in Anticancer Photodynamic Therapy Treatment</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="12965144" href="https://independent.academia.edu/ZahraaYoussef">Zahraa Youssef</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Molecules</p><p class="ds-related-work--abstract ds2-5-body-sm">Photodynamic therapy (PDT) is mainly used to destroy cancerous cells; it combines the action of three components: a photoactivatable molecule or photosensitizer (PS), the light of an appropriate wavelength, and naturally occurring molecular oxygen. After light excitation of the PS, the excited PS then reacts with molecular oxygen to produce reactive oxygen species (ROS), leading to cellular damage. One of the drawbacks of PSs is their lack of solubility in water and body tissue fluids, thereby causing low bioavailability, drug-delivery efficiency, therapeutic efficacy, and ROS production. To improve the water-solubility and/or drug delivery of PSs, using cyclodextrins (CDs) is an interesting strategy. This review describes the in vitro or/and in vivo use of natural and derived CDs to improve antitumoral PDT efficiency in aqueous media. To achieve these goals, three types of binding modes of PSs with CDs are developed: non-covalent CD–PS inclusion complexes, covalent CD–PS conjugates...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Use of Cyclodextrins in Anticancer Photodynamic Therapy Treatment","attachmentId":75285141,"attachmentType":"pdf","work_url":"https://www.academia.edu/62567589/Use_of_Cyclodextrins_in_Anticancer_Photodynamic_Therapy_Treatment","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/62567589/Use_of_Cyclodextrins_in_Anticancer_Photodynamic_Therapy_Treatment"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{"location":"continue-reading-button--sticky-ctas","attachmentId":88590720,"attachmentType":"pdf","workUrl":null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{"location":"download-pdf-button--sticky-ctas","attachmentId":88590720,"attachmentType":"pdf","workUrl":null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_88590720" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="73781627" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/73781627/Photosensitizer_PS_cyanine_dye_CD_conjugates_Impact_of_the_linkers_joining_the_PS_and_CD_moieties_and_their_orientation_in_tumor_uptake_and_photodynamic_therapy_PDT_">Photosensitizer (PS)-cyanine dye (CD) conjugates: Impact of the linkers joining the PS and CD moieties and their orientation in tumor-uptake and photodynamic therapy (PDT)</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58277376" href="https://independent.academia.edu/MasayukiShibata">Masayuki Shibata</a></div><p class="ds-related-work--metadata ds2-5-body-xs">European journal of medicinal chemistry, 2016</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Photosensitizer (PS)-cyanine dye (CD) conjugates: Impact of the linkers joining the PS and CD moieties and their orientation in tumor-uptake and photodynamic therapy (PDT)","attachmentId":82169050,"attachmentType":"pdf","work_url":"https://www.academia.edu/73781627/Photosensitizer_PS_cyanine_dye_CD_conjugates_Impact_of_the_linkers_joining_the_PS_and_CD_moieties_and_their_orientation_in_tumor_uptake_and_photodynamic_therapy_PDT_","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/73781627/Photosensitizer_PS_cyanine_dye_CD_conjugates_Impact_of_the_linkers_joining_the_PS_and_CD_moieties_and_their_orientation_in_tumor_uptake_and_photodynamic_therapy_PDT_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="1" data-entity-id="23046500" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/23046500/Photophysical_characterization_of_imidazolium_substituted_Pd_II_In_III_and_Zn_II_porphyrins_as_photosensitizers_for_photodynamic_therapy">Photophysical characterization of imidazolium-substituted Pd(II), In(III), and Zn(II) porphyrins as photosensitizers for photodynamic therapy</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="44782898" href="https://hms-harvard.academia.edu/MikeHamblin">Mike Hamblin</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Photochemistry and Photobiology A: Chemistry, 2008</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Photophysical characterization of imidazolium-substituted Pd(II), In(III), and Zn(II) porphyrins as photosensitizers for photodynamic therapy","attachmentId":43552577,"attachmentType":"pdf","work_url":"https://www.academia.edu/23046500/Photophysical_characterization_of_imidazolium_substituted_Pd_II_In_III_and_Zn_II_porphyrins_as_photosensitizers_for_photodynamic_therapy","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/23046500/Photophysical_characterization_of_imidazolium_substituted_Pd_II_In_III_and_Zn_II_porphyrins_as_photosensitizers_for_photodynamic_therapy"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="2" data-entity-id="101048121" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/101048121/Inclusion_complex_vs_conjugation_of_hydrophobic_photosensitizers_with_%CE%B2_cyclodextrin_Improved_disaggregation_and_photodynamic_therapy_efficacy_against_glioblastoma_cells">Inclusion complex vs. conjugation of hydrophobic photosensitizers with β-cyclodextrin: Improved disaggregation and photodynamic therapy efficacy against glioblastoma cells</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="267842887" href="https://independent.academia.edu/SAcherar">Samir Acherar</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Materials Science and Engineering: C, 2019</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" 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href="https://www.academia.edu/101048121/Inclusion_complex_vs_conjugation_of_hydrophobic_photosensitizers_with_%CE%B2_cyclodextrin_Improved_disaggregation_and_photodynamic_therapy_efficacy_against_glioblastoma_cells"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="3" data-entity-id="10739956" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/10739956/Tetrakis_4_pyridyl_porphyrin_Supramolecular_Complexes_with_Cyclodextrins_in_Aqueous_Solution">Tetrakis(4-pyridyl)porphyrin Supramolecular Complexes with Cyclodextrins in Aqueous Solution</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="26176848" href="https://independent.academia.edu/PinalysaCosma">Pinalysa Cosma</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Photochemistry and Photobiology, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Tetrakis(4-pyridyl)porphyrin Supramolecular Complexes with Cyclodextrins in Aqueous Solution","attachmentId":47164114,"attachmentType":"pdf","work_url":"https://www.academia.edu/10739956/Tetrakis_4_pyridyl_porphyrin_Supramolecular_Complexes_with_Cyclodextrins_in_Aqueous_Solution","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/10739956/Tetrakis_4_pyridyl_porphyrin_Supramolecular_Complexes_with_Cyclodextrins_in_Aqueous_Solution"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="4" data-entity-id="31298869" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/31298869/Structures_and_Electronic_Absorption_Spectra_of_a_Recently_Synthesised_Class_of_Photodynamic_Therapy_Agents">Structures and Electronic Absorption Spectra of a Recently Synthesised Class of Photodynamic Therapy Agents</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="32892559" href="https://unical-it.academia.edu/NinoRusso">Nino Russo</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Chemistry - A European Journal, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{"location":"wsj-grid-card-download-pdf-modal","work_title":"Structures and Electronic Absorption Spectra of a Recently Synthesised Class of Photodynamic Therapy Agents","attachmentId":51694925,"attachmentType":"pdf","work_url":"https://www.academia.edu/31298869/Structures_and_Electronic_Absorption_Spectra_of_a_Recently_Synthesised_Class_of_Photodynamic_Therapy_Agents","alternativeTracking":true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/31298869/Structures_and_Electronic_Absorption_Spectra_of_a_Recently_Synthesised_Class_of_Photodynamic_Therapy_Agents"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="5" data-entity-id="66605093" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/66605093/A_Molecular_Dynamics_Study_of_a_Photodynamic_Sensitizer_for_Cancer_Cells_Inclusion_Complexes_of_%CE%B3_Cyclodextrins_with_C70">A Molecular Dynamics Study of a Photodynamic Sensitizer for Cancer Cells: Inclusion Complexes of γ-Cyclodextrins with C70</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31444162" 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