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bc=document.querySelector(".breadcrumb_container");if(isOverflown(bc)){bc.parentNode.classList.add("mobile-bc-overflow");bc.parentNode.classList.remove("mobile-no-bc-overflow");}else{bc.parentNode.classList.add("mobile-no-bc-overflow");bc.parentNode.classList.remove("mobile-bc-overflow");}bc.parentNode.classList.add("showMobileBreadcrumbs");}});</script> <div id="main_layer_max"><div id="frame_layer"><div class="tag top"><span class="tag-before"></span><span class="tag-type" data-tag-id="whitePapers">Livre Blanc</span><span class="tag-after"></span></div><h1 id="title" class="standardAdjustable_title"> La spectrophotométrie uv visible au service de la recherche sur les vaccins à ARNm </h1><div class="tag bottom"><span class="tag-before"></span><span class="tag-type">Livre Blanc</span><span class="tag-after"></span></div><h2>Livre blanc sur la R&D et le contrôle de la qualité des vaccins à ARNm</h2><div id="content"><link rel="stylesheet" href="/etc/designs/mt/widgets/misc/standardadjustable.min-v46.css" type="text/css"><script src="/etc/designs/mt/widgets/misc/standardadjustable.min-v46.js"></script> <div class="mcolandingpagecontent-wrap"><div class="mcolandingpagecontent"><div class="header-section width_60_40"><div class="right-par"><div class="lpImage smallimage"><link rel="stylesheet" href="/etc/designs/mt/widgets/misc/smallimage.min-v46.css" type="text/css"><div id="sm_img_bHBJbWFnZV9XaGl0ZVBhcGVyX21STkFfMjMweDMyNQ"><div class="imageDiv"><div class="imageDiv"><table class="imageDiv" style=""><tbody class="imageDiv"><tr class="imageDiv"><td class="imageDiv"><picture><source srcset="/dam/Analytical/uv-vis/uvvis-library/WhitePaper_mRNA_230x325.jpg/_jcr_content/renditions/cq5dam.web.121.121.webp" media="(min-width: 0px) and (max-width: 320px)" type="image/webp"><source srcset="/dam/Analytical/uv-vis/uvvis-library/WhitePaper_mRNA_230x325.jpg/_jcr_content/renditions/cq5dam.web.128.128.jpeg" media="(min-width: 0px) and (max-width: 320px)" type="image/jpeg"><source srcset="/dam/Analytical/uv-vis/uvvis-library/WhitePaper_mRNA_230x325.jpg/_jcr_content/renditions/original.webp" media="(min-width: 321px) and (max-width: 480px)" type="image/webp"><source srcset="/dam/Analytical/uv-vis/uvvis-library/WhitePaper_mRNA_230x325.jpg/_jcr_content/renditions/original.webp" media="(min-width: 481px) and (max-width: 640px)" type="image/webp"><source srcset="/dam/Analytical/uv-vis/uvvis-library/WhitePaper_mRNA_230x325.jpg/_jcr_content/renditions/original.webp" media="(min-width: 641px) and (max-width: 800px)" type="image/webp"><source srcset="/dam/Analytical/uv-vis/uvvis-library/WhitePaper_mRNA_230x325.jpg/_jcr_content/renditions/original.webp" media="(min-width: 801px)" type="image/webp"><img loading="lazy" loading="lazy" src="/dam/Analytical/uv-vis/uvvis-library/WhitePaper_mRNA_230x325.jpg/_jcr_content/renditions/cq5dam.web.1280.1280.jpeg" alt="Ce livre blanc explique comment la spectrophotométrie uv visible peut faciliter le processus de R&amp;D et de fabrication d'un vaccin à base d'ARNm." title="Ce livre blanc explique comment la spectrophotométrie uv visible peut faciliter le processus de R&amp;D et de fabrication d'un vaccin à base d'ARNm." class="smImg_imageBorder"></picture></td></tr><tr class="imageDiv"><td class="imageDiv"><div class="description "> Ce livre blanc explique comment la spectrophotométrie uv visible peut faciliter le processus de R&amp;D et de fabrication d'un vaccin à base d'ARNm. </div></td></tr></tbody></table></div></div></div><script type="text/javascript">$(window).load(function(){$("#sm_img_bHBJbWFnZV9XaGl0ZVBhcGVyX21STkFfMjMweDMyNQ").imagesLoaded().always(function(instance){if(instance.images.length>0){var targetImage=$(instance.images[0].img);if(targetImage.width()>$(window).width()){targetImage.css("width","100%");}}});});</script> </div><div class="lpRightPar parsys"></div></div><div class="left-par"><div class="lpIntrotext text parbase"><p>Lors de la pandémie de coronavirus COVID-19, les vaccins ARNm (ARN messager) ont permis une vaccination efficace. La recherche et le développement de ces vaccins dépendent principalement de leur qualité pour assurer une bonne tolérance, une bonne efficacité et une disponibilité rapide, qui peuvent être évaluées à l'aide de techniques analytiques avancées.</p><p>Ce document décrit la spectrophotométrie uv visible comme une technique simple, rentable et donc largement utilisée qui permet une analyse qualitative et quantitative efficace et précise des acides nucléiques. Le livre blanc traite en outre des vaccins/ candidats vaccins ARNm prometteurs et du potentiel de l'analyse UV Vis pour aider à la caractérisation précise et rapide des matières premières et des produits finis tout au long des processus de R&D et de fabrication.</p></div><div class="lpLeftPar parsys"><div class="feedbackb section"><div class="fbB_formView fb_standard_view_lpLeftPar_lpFeedbackb"><div id="fbB_introBtnText_table_lpLeftPar_lpFeedbackb"><form method="get" action="/ch/fr/home/library/white-papers/lab-analytical-instruments/mRNA-vaccine-research.fb.lpLeftPar.lpFeedbackb.html" style="display:inline-block;"><button class="fb-button-p5a btn-action btn-primary btn-large" data-aa-catId="30" aria-label="Téléchargez le livre blanc"><span> Téléchargez le livre blanc </span></button></form></div></div></div></div></div></div><div class="content-section clear"><div class="lpMainText text parbase"><p><b>Table des matières</b></p><ol><li>Introduction<br/></li><li>Contrôle de la qualité des vaccins<br/></li><li>Vaccins à base d'acide nucléique et nanoparticules lipidiques (LNP)<br/></li><li>Fabrication de vaccins ARNm-PNL pour COVID-19<br/></li><li>Utilisation du spectrophotomètre uv vis dans le contrôle de la qualité des vaccins à ARNm<br/></li><li>Domaines de caractérisation possibles pour la spectrophotométrie UV visible</li><li>Notes d'application et littérature à l'appui<br/></li><li>Glossaire<br/></li><li>Références</li></ol></div><div class="mainpar parsys"><div class="embeddedvideo section"><link rel="stylesheet" href="/etc/designs/mt/widgets/misc/embeddedvideo.min-v46.css" type="text/css"><script defer src="/etc/designs/mt/widgets/misc/embeddedvideo.min-v46.js"></script> <div class="embeddedVideo" data-advanced-option="false" data-has-preview-image="false" data-video-id="NxrYLRcnPXQ" data-component-id="-69621329"><h3 class="mediaLabel hide "></h3><div id="mediaContainerWrapper_-69621329" style="max-width: 560px; width: 100%"><div class="mediaContainer 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class="tab_navigation_mb title">Produits</div><div class="center"><div class="content accordion_blue_grey layout_ mb_gridLayout"><div class="mbItemGrid"><div class="mbItemWrapper rowLevel_2"><div class="mbItem"><div class="image"><a href="/ch/fr/home/products/Laboratory_Analytics_Browse/uv-vis-spectrometers/micro-uv-vis-spectrometers.html"><img loading="lazy" src="/dam/Analytical/uv-vis/uvvis-preview/spectrophotometry_250.png/_jcr_content/renditions/cq5dam.web.1280.1280.png" align="right" alt="Spectrophotométrie à microvolume avec les instruments METTLER TOLEDO" title="Spectrophotométrie à microvolume avec les instruments METTLER TOLEDO"/></a><div class="itemInfo"><div class="mbItemTitle"><a href="/ch/fr/home/products/Laboratory_Analytics_Browse/uv-vis-spectrometers/micro-uv-vis-spectrometers.html"> Spectrophotomètres à microvolume UV Visible </a></div><div class="description hyphenate"><a class="noStyle" href="/ch/fr/home/products/Laboratory_Analytics_Browse/uv-vis-spectrometers/micro-uv-vis-spectrometers.html"> Deux instruments en un pour les mesures de microvolumes et les mesures en cuves conventionnelles de 1 cm pour la recherche en sciences de la vie. </a></div><div class="feedback_wrapper"></div></div></div></div></div><div class="mbVerticalSeparator rowLevel_2"></div><div class="mbItemWrapper rowLevel_2"><div class="mbItem"><div class="image"><a href="/ch/fr/home/products/Laboratory_Analytics_Browse/uv-vis-spectrometers/cuvette-uv-vis-spectrometers.html"><img loading="lazy" src="/dam/Analytical/uv-vis/uv-thumbnails/UVVIS_Excellence_thumbnail_250x250.png/_jcr_content/renditions/cq5dam.web.1280.1280.png" align="right" alt="Spectrophotomètres à cuve UV Visible METTLER TOLEDO" title="Spectrophotomètres à cuve UV Visible METTLER TOLEDO"/></a><div class="itemInfo"><div class="mbItemTitle"><a href="/ch/fr/home/products/Laboratory_Analytics_Browse/uv-vis-spectrometers/cuvette-uv-vis-spectrometers.html"> Spectrophotomètres à cuve UV Visible </a></div><div class="description hyphenate"><a class="noStyle" href="/ch/fr/home/products/Laboratory_Analytics_Browse/uv-vis-spectrometers/cuvette-uv-vis-spectrometers.html"> Les produits de la gamme UV Vis Excellence couvrent l'ensemble de vos besoins, du contrôle qualité jusqu'au suivi de la conformité aux réglementations... </a></div><div class="feedback_wrapper"></div></div></div></div></div><div class="mbItemWrapper rowLevel_2"><div class="mbItem"><div class="image"><a href="/shop/ch/fr/product/30254728/spectrophotometre-uv5-bio.html"><img loading="lazy" src="https://www.mt.com/images/Thumbnail/MainImage/30254728.jpg" align="right" alt="Spectrophotomètre UV5 Bio" title="Spectrophotomètre UV5 Bio"/></a><div class="itemInfo"><div class="mbItemTitle"><a href="/shop/ch/fr/product/30254728/spectrophotometre-uv5-bio.html"> Spectrophotomètre UV5 Bio </a></div><div class="description hyphenate"><a class="noStyle" href="/shop/ch/fr/product/30254728/spectrophotometre-uv5-bio.html"> Le spectrophotomètre UV/Vis compact de paillasse UV5Bio est la solution idéale pour les laboratoires analysant des échantillons biologiques ou effectu... </a></div><div class="feedback_wrapper"></div></div></div></div></div><div class="mbVerticalSeparator rowLevel_2"></div><div class="mbItemWrapper rowLevel_2"><div class="mbItem"><div class="itemInfo"><div class="mbItemTitle"><a href="/ch/fr/home/perm-lp/product-organizations/ana/thermostating-uvvis-peltier-temperature-control.html"> Un thermostat adapté… </a></div><div class="description hyphenate"></div><div class="feedback_wrapper"><form method="get" action="/ch/fr/home/perm-lp/product-organizations/ana/thermostating-uvvis-peltier-temperature-control.fb.standardpar.standalonemoodimage_683471724.feedbackb.html"><button class="fb-button-p5a btn-action btn-primary" aria-label="Demande d'information"><span>Demande d'information</span></button></form></div></div></div></div></div></div></div></div><div class="mbSeparator"></div></div><div class="matchingblockpush section"><div id="mb_mcolandingpagecontentmainparmatchingblockpush_162788500" class="matching_block_wrapper matching_box mb_gridLayout" data-swiftype-index="false"><input type="hidden" name="mbTabItemsCount" value="1"/><div class="tab_navigation_mb title">Sur le même sujet</div><div class="center"><div class="content accordion_blue_grey layout_ mb_gridLayout"><div class="mbItemGrid"><div class="mbItemWrapper rowLevel_2"><div class="mbItem"><div class="image"><a href="/ch/fr/home/library/guides/laboratory-division/life-science/uvvis-toolbox-for-life-sciences.html"><img loading="lazy" src="/dam/direct-upload/thumbnails/library/guides/laboratory-division/life-science/uvvis-toolbox-for-life-sciences/UV-Vis-Toolbox-for-Life-Sciences.jpg/_jcr_content/renditions/cq5dam.web.1280.1280.jpeg" align="right" alt="Boîte à outils Sciences de la vie pour la spectroscopie UV VIS" title="Boîte à outils Sciences de la vie pour la spectroscopie UV VIS"/></a><div class="itemInfo"><div class="mbItemTitle"><a href="/ch/fr/home/library/guides/laboratory-division/life-science/uvvis-toolbox-for-life-sciences.html"> Boîte à outils Sciences de la vie pour la spectroscopie UV VIS </a></div><div class="description hyphenate"><a class="noStyle" href="/ch/fr/home/library/guides/laboratory-division/life-science/uvvis-toolbox-for-life-sciences.html"> Notre boîte à outils de spectrophotométrie UV VIS pour les sciences de la vie vous aide à analyser les acides nucléiques, les protéines et les culture... </a></div><div class="feedback_wrapper"><form method="get" action="/ch/fr/home/library/guides/laboratory-division/life-science/uvvis-toolbox-for-life-sciences.fb.mainpar.feedbackb.html"><button class="fb-button-p5a btn-action btn-primary" aria-label="Télécharger la boîte à outils UV VIS pour les sciences de la vie"><span>Télécharger la boîte à outils UV VIS pour les sciences de la vie</span></button></form></div></div></div></div></div><div class="mbVerticalSeparator rowLevel_2"></div><div class="mbItemWrapper rowLevel_2"><div class="mbItem"><div class="itemInfo"><div class="mbItemTitle"><a href="/ch/fr/home/supportive_content/ana_chem_applications/uvvis/M9501.html"> Nucleic Acid - UV Vis Spectroscopy </a></div><div class="description hyphenate"><a class="noStyle" href="/ch/fr/home/supportive_content/ana_chem_applications/uvvis/M9501.html"> Nucleic acid concentration determination is a common application in the life science industry. Click for more information on sample preparation, the e... </a></div><div class="feedback_wrapper"><form method="get" action="/ch/fr/home/supportive_content/ana_chem_applications/uvvis/M9501.fb.standardpar.feedbackb.html"><button class="fb-button-p5a btn-action btn-primary" aria-label="Proceed to Download Page"><span>Proceed to Download Page</span></button></form></div></div></div></div><div class="mbItemWrapper rowLevel_3"><div class="mbItem"><div class="mbItemTitle"><a href="/ch/fr/home/library/on-demand-webinars/lab-analytical-instruments/life-science-applications-in-uvvis-spectroscopy.html"> Applications de spectroscopie UV/Vis dans les sciences de la vie </a></div><div class="image"><a href="/ch/fr/home/library/on-demand-webinars/lab-analytical-instruments/life-science-applications-in-uvvis-spectroscopy.html"><img loading="lazy" src="/dam/direct-upload/thumbnails/library/on-demand-webinars/lab-analytical-instruments/life-science-applications-in-uvvis-spectroscopy/thumb-life-science-applications-in-uvvis.jpg/_jcr_content/renditions/cq5dam.web.1280.1280.jpeg" align="right" alt="Sciences de la vie" title="Sciences de la vie"/></a><div class="itemInfo"><div class="description hyphenate"><a class="noStyle" href="/ch/fr/home/library/on-demand-webinars/lab-analytical-instruments/life-science-applications-in-uvvis-spectroscopy.html"> Les solutions d'acide nucléique (ADN/ARN) et de protéines sont souvent analysées par spectroscopie UV/Vis. Ce Web-séminaire fournit des informations c... </a></div><div class="feedback_wrapper"><form method="get" action="/ch/fr/home/library/on-demand-webinars/lab-analytical-instruments/life-science-applications-in-uvvis-spectroscopy.fb.lpLeftPar.feedbackb.html"><button class="fb-button-p5a btn-action btn-primary" aria-label="Inscrivez-vous à un web-séminaire en ligne"><span>Inscrivez-vous à un web-séminaire en ligne</span></button></form></div></div></div></div></div><div class="mbVerticalSeparator rowLevel_3"></div><div class="mbItemWrapper rowLevel_3"><div class="mbItem"><div class="mbItemTitle"><a href="/ch/fr/home/library/white-papers/lab-analytical-instruments/spectrophotometric-covid19-vaccine-analysis.html"> Applications UV VIS pour rechercher le vaccin contre la COVID-19 </a></div><div class="image"><a href="/ch/fr/home/library/white-papers/lab-analytical-instruments/spectrophotometric-covid19-vaccine-analysis.html"><img loading="lazy" 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blanc"><span>Télécharger le livre blanc</span></button></form></div></div></div></div></div><div class="mbVerticalSeparator rowLevel_3"></div><div class="mbItemWrapper rowLevel_3"><div class="mbItem"><div class="mbItemTitle"><a href="/ch/fr/home/library/tips-and-tricks/lab-analytical-instruments/nucleic-acid-analysis.html"> Analyse des acides nucléiques </a></div><div class="image"><a href="/ch/fr/home/library/tips-and-tricks/lab-analytical-instruments/nucleic-acid-analysis.html"><img loading="lazy" src="/dam/Analytical/uv-vis/uvvis-library/nucleic-acid-analysis-poster.jpg/_jcr_content/renditions/cq5dam.web.1280.1280.jpeg" align="right" alt="Nucleic Acid Analysis" title="Nucleic Acid Analysis"/></a><div class="itemInfo"><div class="description hyphenate"><a class="noStyle" href="/ch/fr/home/library/tips-and-tricks/lab-analytical-instruments/nucleic-acid-analysis.html"> Le nouveau poster "Analyse des acides nucléiques par spectroscopie d'absorbance" résume toutes les informations clés 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