CINXE.COM

<!DOCTYPE html> <html lang="en" dir="ltr" prefix="content: http://purl.org/rss/1.0/modules/content/ dc: http://purl.org/dc/terms/ foaf: http://xmlns.com/foaf/0.1/ rdfs: http://www.w3.org/2000/01/rdf-schema# sioc: http://rdfs.org/sioc/ns# sioct: http://rdfs.org/sioc/types# skos: http://www.w3.org/2004/02/skos/core# xsd: http://www.w3.org/2001/XMLSchema#"> <head><script type="text/javascript">(window.NREUM||(NREUM={})).init={privacy:{cookies_enabled:true},ajax:{deny_list:[]},session_replay:{sampling_rate:10.0,mask_text_selector:"*",block_selector:"",mask_input_options:{},mask_all_inputs:true,enabled:true,error_sampling_rate:100.0},session_trace:{sampling_rate:10.0,mode:"PROBABILISTIC",enabled:true,error_sampling_rate:100.0}};(window.NREUM||(NREUM={})).loader_config={xpid:"UA8FUVBADwsIV1VaAgMP",licenseKey:"76fb58fb05",applicationID:"788348528"};;/*! For license information please see nr-loader-full-1.274.0.min.js.LICENSE.txt */ (()=>{var e,t,r={8122:(e,t,r)=>{"use strict";r.d(t,{a:()=>i});var n=r(944);function i(e,t){try{if(!e||"object"!=typeof e)return(0,n.R)(3);if(!t||"object"!=typeof t)return(0,n.R)(4);const r=Object.create(Object.getPrototypeOf(t),Object.getOwnPropertyDescriptors(t)),o=0===Object.keys(r).length?e:r;for(let a in o)if(void 0!==e[a])try{if(null===e[a]){r[a]=null;continue}Array.isArray(e[a])&&Array.isArray(t[a])?r[a]=Array.from(new Set([...e[a],...t[a]])):"object"==typeof e[a]&&"object"==typeof t[a]?r[a]=i(e[a],t[a]):r[a]=e[a]}catch(e){(0,n.R)(1,e)}return r}catch(e){(0,n.R)(2,e)}}},2555:(e,t,r)=>{"use strict";r.d(t,{Vp:()=>c,fn:()=>s,x1:()=>d});var n=r(384),i=r(8122);const o={beacon:n.NT.beacon,errorBeacon:n.NT.errorBeacon,licenseKey:void 0,applicationID:void 0,sa:void 0,queueTime:void 0,applicationTime:void 0,ttGuid:void 0,user:void 0,account:void 0,product:void 0,extra:void 0,jsAttributes:{},userAttributes:void 0,atts:void 0,transactionName:void 0,tNamePlain:void 0},a={};function s(e){try{const t=c(e);return!!t.licenseKey&&!!t.errorBeacon&&!!t.applicationID}catch(e){return!1}}function c(e){if(!e)throw new Error("All info objects require an agent identifier!");if(!a[e])throw new Error("Info for ".concat(e," was never set"));return a[e]}function d(e,t){if(!e)throw new Error("All info objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.info=a[e])}},9417:(e,t,r)=>{"use strict";r.d(t,{D0:()=>h,gD:()=>p,xN:()=>g});var n=r(993);const i=e=>{if(!e||"string"!=typeof e)return!1;try{document.createDocumentFragment().querySelector(e)}catch{return!1}return!0};var o=r(2614),a=r(944),s=r(384),c=r(8122);const d="[data-nr-mask]",u=()=>{const e={mask_selector:"*",block_selector:"[data-nr-block]",mask_input_options:{color:!1,date:!1,"datetime-local":!1,email:!1,month:!1,number:!1,range:!1,search:!1,tel:!1,text:!1,time:!1,url:!1,week:!1,textarea:!1,select:!1,password:!0}};return{ajax:{deny_list:void 0,block_internal:!0,enabled:!0,harvestTimeSeconds:10,autoStart:!0},distributed_tracing:{enabled:void 0,exclude_newrelic_header:void 0,cors_use_newrelic_header:void 0,cors_use_tracecontext_headers:void 0,allowed_origins:void 0},feature_flags:[],generic_events:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},harvest:{tooManyRequestsDelay:60},jserrors:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},logging:{enabled:!0,harvestTimeSeconds:10,autoStart:!0,level:n.p_.INFO},metrics:{enabled:!0,autoStart:!0},obfuscate:void 0,page_action:{enabled:!0},page_view_event:{enabled:!0,autoStart:!0},page_view_timing:{enabled:!0,harvestTimeSeconds:30,autoStart:!0},performance:{capture_marks:!1,capture_measures:!1},privacy:{cookies_enabled:!0},proxy:{assets:void 0,beacon:void 0},session:{expiresMs:o.wk,inactiveMs:o.BB},session_replay:{autoStart:!0,enabled:!1,harvestTimeSeconds:60,preload:!1,sampling_rate:10,error_sampling_rate:100,collect_fonts:!1,inline_images:!1,fix_stylesheets:!0,mask_all_inputs:!0,get mask_text_selector(){return e.mask_selector},set mask_text_selector(t){i(t)?e.mask_selector="".concat(t,",").concat(d):""===t||null===t?e.mask_selector=d:(0,a.R)(5,t)},get block_class(){return"nr-block"},get ignore_class(){return"nr-ignore"},get mask_text_class(){return"nr-mask"},get block_selector(){return e.block_selector},set block_selector(t){i(t)?e.block_selector+=",".concat(t):""!==t&&(0,a.R)(6,t)},get mask_input_options(){return e.mask_input_options},set mask_input_options(t){t&&"object"==typeof t?e.mask_input_options={...t,password:!0}:(0,a.R)(7,t)}},session_trace:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},soft_navigations:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},spa:{enabled:!0,harvestTimeSeconds:10,autoStart:!0},ssl:void 0,user_actions:{enabled:!0}}},l={},f="All configuration objects require an agent identifier!";function h(e){if(!e)throw new Error(f);if(!l[e])throw new Error("Configuration for ".concat(e," was never set"));return l[e]}function g(e,t){if(!e)throw new Error(f);l[e]=(0,c.a)(t,u());const r=(0,s.nY)(e);r&&(r.init=l[e])}function p(e,t){if(!e)throw new Error(f);var r=h(e);if(r){for(var n=t.split("."),i=0;i<n.length-1;i++)if("object"!=typeof(r=r[n[i]]))return;r=r[n[n.length-1]]}return r}},5603:(e,t,r)=>{"use strict";r.d(t,{a:()=>c,o:()=>s});var n=r(384),i=r(8122);const o={accountID:void 0,trustKey:void 0,agentID:void 0,licenseKey:void 0,applicationID:void 0,xpid:void 0},a={};function s(e){if(!e)throw new Error("All loader-config objects require an agent identifier!");if(!a[e])throw new Error("LoaderConfig for ".concat(e," was never set"));return a[e]}function c(e,t){if(!e)throw new Error("All loader-config objects require an agent identifier!");a[e]=(0,i.a)(t,o);const r=(0,n.nY)(e);r&&(r.loader_config=a[e])}},3371:(e,t,r)=>{"use strict";r.d(t,{V:()=>f,f:()=>l});var n=r(8122),i=r(384),o=r(6154),a=r(9324);let s=0;const c={buildEnv:a.F3,distMethod:a.Xs,version:a.xv,originTime:o.WN},d={customTransaction:void 0,disabled:!1,isolatedBacklog:!1,loaderType:void 0,maxBytes:3e4,onerror:void 0,ptid:void 0,releaseIds:{},appMetadata:{},session:void 0,denyList:void 0,timeKeeper:void 0,obfuscator:void 0},u={};function l(e){if(!e)throw new Error("All runtime objects require an agent identifier!");if(!u[e])throw new Error("Runtime for ".concat(e," was never set"));return u[e]}function f(e,t){if(!e)throw new Error("All runtime objects require an agent identifier!");u[e]={...(0,n.a)(t,d),...c},Object.hasOwnProperty.call(u[e],"harvestCount")||Object.defineProperty(u[e],"harvestCount",{get:()=>++s});const r=(0,i.nY)(e);r&&(r.runtime=u[e])}},9324:(e,t,r)=>{"use strict";r.d(t,{F3:()=>i,Xs:()=>o,Yq:()=>a,xv:()=>n});const n="1.274.0",i="PROD",o="CDN",a="^2.0.0-alpha.17"},6154:(e,t,r)=>{"use strict";r.d(t,{OF:()=>d,RI:()=>i,WN:()=>f,bv:()=>o,gm:()=>a,lR:()=>l,m:()=>c,mw:()=>s,sb:()=>u});var n=r(1863);const i="undefined"!=typeof window&&!!window.document,o="undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self.navigator instanceof WorkerNavigator||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis.navigator instanceof WorkerNavigator),a=i?window:"undefined"!=typeof WorkerGlobalScope&&("undefined"!=typeof self&&self instanceof WorkerGlobalScope&&self||"undefined"!=typeof globalThis&&globalThis instanceof WorkerGlobalScope&&globalThis),s=Boolean("hidden"===a?.document?.visibilityState),c=""+a?.location,d=/iPad|iPhone|iPod/.test(a.navigator?.userAgent),u=d&&"undefined"==typeof SharedWorker,l=(()=>{const e=a.navigator?.userAgent?.match(/Firefox[/\s](\d+\.\d+)/);return Array.isArray(e)&&e.length>=2?+e[1]:0})(),f=Date.now()-(0,n.t)()},7295:(e,t,r)=>{"use strict";r.d(t,{Xv:()=>a,gX:()=>i,iW:()=>o});var n=[];function i(e){if(!e||o(e))return!1;if(0===n.length)return!0;for(var t=0;t<n.length;t++){var r=n[t];if("*"===r.hostname)return!1;if(s(r.hostname,e.hostname)&&c(r.pathname,e.pathname))return!1}return!0}function o(e){return void 0===e.hostname}function a(e){if(n=[],e&&e.length)for(var t=0;t<e.length;t++){let r=e[t];if(!r)continue;0===r.indexOf("http://")?r=r.substring(7):0===r.indexOf("https://")&&(r=r.substring(8));const i=r.indexOf("/");let o,a;i>0?(o=r.substring(0,i),a=r.substring(i)):(o=r,a="");let[s]=o.split(":");n.push({hostname:s,pathname:a})}}function s(e,t){return!(e.length>t.length)&&t.indexOf(e)===t.length-e.length}function c(e,t){return 0===e.indexOf("/")&&(e=e.substring(1)),0===t.indexOf("/")&&(t=t.substring(1)),""===e||e===t}},1687:(e,t,r)=>{"use strict";r.d(t,{Ak:()=>c,Ze:()=>l,x3:()=>d});var n=r(7836),i=r(3606),o=r(860),a=r(2646);const s={};function c(e,t){const r={staged:!1,priority:o.P3[t]||0};u(e),s[e].get(t)||s[e].set(t,r)}function d(e,t){e&&s[e]&&(s[e].get(t)&&s[e].delete(t),h(e,t,!1),s[e].size&&f(e))}function u(e){if(!e)throw new Error("agentIdentifier required");s[e]||(s[e]=new Map)}function l(e="",t="feature",r=!1){if(u(e),!e||!s[e].get(t)||r)return h(e,t);s[e].get(t).staged=!0,f(e)}function f(e){const t=Array.from(s[e]);t.every((([e,t])=>t.staged))&&(t.sort(((e,t)=>e[1].priority-t[1].priority)),t.forEach((([t])=>{s[e].delete(t),h(e,t)})))}function h(e,t,r=!0){const o=e?n.ee.get(e):n.ee,s=i.i.handlers;if(!o.aborted&&o.backlog&&s){if(r){const e=o.backlog[t],r=s[t];if(r){for(let t=0;e&&t<e.length;++t)g(e[t],r);Object.entries(r).forEach((([e,t])=>{Object.values(t||{}).forEach((t=>{t[0]?.on&&t[0]?.context()instanceof a.y&&t[0].on(e,t[1])}))}))}}o.isolatedBacklog||delete s[t],o.backlog[t]=null,o.emit("drain-"+t,[])}}function g(e,t){var r=e[1];Object.values(t[r]||{}).forEach((t=>{var r=e[0];if(t[0]===r){var n=t[1],i=e[3],o=e[2];n.apply(i,o)}}))}},7836:(e,t,r)=>{"use strict";r.d(t,{P:()=>c,ee:()=>d});var n=r(384),i=r(8990),o=r(3371),a=r(2646),s=r(5607);const c="nr@context:".concat(s.W),d=function e(t,r){var n={},s={},u={},l=!1;try{l=16===r.length&&(0,o.f)(r).isolatedBacklog}catch(e){}var f={on:g,addEventListener:g,removeEventListener:function(e,t){var r=n[e];if(!r)return;for(var i=0;i<r.length;i++)r[i]===t&&r.splice(i,1)},emit:function(e,r,n,i,o){!1!==o&&(o=!0);if(d.aborted&&!i)return;t&&o&&t.emit(e,r,n);for(var a=h(n),c=p(e),u=c.length,l=0;l<u;l++)c[l].apply(a,r);var g=v()[s[e]];g&&g.push([f,e,r,a]);return a},get:m,listeners:p,context:h,buffer:function(e,t){const r=v();if(t=t||"feature",f.aborted)return;Object.entries(e||{}).forEach((([e,n])=>{s[n]=t,t in r||(r[t]=[])}))},abort:function(){f._aborted=!0,Object.keys(f.backlog).forEach((e=>{delete f.backlog[e]}))},isBuffering:function(e){return!!v()[s[e]]},debugId:r,backlog:l?{}:t&&"object"==typeof t.backlog?t.backlog:{},isolatedBacklog:l};return Object.defineProperty(f,"aborted",{get:()=>{let e=f._aborted||!1;return e||(t&&(e=t.aborted),e)}}),f;function h(e){return e&&e instanceof a.y?e:e?(0,i.I)(e,c,(()=>new a.y(c))):new a.y(c)}function g(e,t){n[e]=p(e).concat(t)}function p(e){return n[e]||[]}function m(t){return u[t]=u[t]||e(f,t)}function v(){return f.backlog}}(void 0,"globalEE"),u=(0,n.Zm)();u.ee||(u.ee=d)},2646:(e,t,r)=>{"use strict";r.d(t,{y:()=>n});class n{constructor(e){this.contextId=e}}},9908:(e,t,r)=>{"use strict";r.d(t,{d:()=>n,p:()=>i});var n=r(7836).ee.get("handle");function i(e,t,r,i,o){o?(o.buffer([e],i),o.emit(e,t,r)):(n.buffer([e],i),n.emit(e,t,r))}},3606:(e,t,r)=>{"use strict";r.d(t,{i:()=>o});var n=r(9908);o.on=a;var i=o.handlers={};function o(e,t,r,o){a(o||n.d,i,e,t,r)}function a(e,t,r,i,o){o||(o="feature"),e||(e=n.d);var a=t[o]=t[o]||{};(a[r]=a[r]||[]).push([e,i])}},3878:(e,t,r)=>{"use strict";function n(e,t){return{capture:e,passive:!1,signal:t}}function i(e,t,r=!1,i){window.addEventListener(e,t,n(r,i))}function o(e,t,r=!1,i){document.addEventListener(e,t,n(r,i))}r.d(t,{DD:()=>o,jT:()=>n,sp:()=>i})},5607:(e,t,r)=>{"use strict";r.d(t,{W:()=>n});const n=(0,r(9566).bz)()},9566:(e,t,r)=>{"use strict";r.d(t,{LA:()=>s,ZF:()=>c,bz:()=>a,el:()=>d});var n=r(6154);const i="xxxxxxxx-xxxx-4xxx-yxxx-xxxxxxxxxxxx";function o(e,t){return e?15&e[t]:16*Math.random()|0}function a(){const e=n.gm?.crypto||n.gm?.msCrypto;let t,r=0;return e&&e.getRandomValues&&(t=e.getRandomValues(new Uint8Array(30))),i.split("").map((e=>"x"===e?o(t,r++).toString(16):"y"===e?(3&o()|8).toString(16):e)).join("")}function s(e){const t=n.gm?.crypto||n.gm?.msCrypto;let r,i=0;t&&t.getRandomValues&&(r=t.getRandomValues(new Uint8Array(e)));const a=[];for(var s=0;s<e;s++)a.push(o(r,i++).toString(16));return a.join("")}function c(){return s(16)}function d(){return s(32)}},2614:(e,t,r)=>{"use strict";r.d(t,{BB:()=>a,H3:()=>n,g:()=>d,iL:()=>c,tS:()=>s,uh:()=>i,wk:()=>o});const n="NRBA",i="SESSION",o=144e5,a=18e5,s={STARTED:"session-started",PAUSE:"session-pause",RESET:"session-reset",RESUME:"session-resume",UPDATE:"session-update"},c={SAME_TAB:"same-tab",CROSS_TAB:"cross-tab"},d={OFF:0,FULL:1,ERROR:2}},1863:(e,t,r)=>{"use strict";function n(){return Math.floor(performance.now())}r.d(t,{t:()=>n})},7485:(e,t,r)=>{"use strict";r.d(t,{D:()=>i});var n=r(6154);function i(e){if(0===(e||"").indexOf("data:"))return{protocol:"data"};try{const t=new URL(e,location.href),r={port:t.port,hostname:t.hostname,pathname:t.pathname,search:t.search,protocol:t.protocol.slice(0,t.protocol.indexOf(":")),sameOrigin:t.protocol===n.gm?.location?.protocol&&t.host===n.gm?.location?.host};return r.port&&""!==r.port||("http:"===t.protocol&&(r.port="80"),"https:"===t.protocol&&(r.port="443")),r.pathname&&""!==r.pathname?r.pathname.startsWith("/")||(r.pathname="/".concat(r.pathname)):r.pathname="/",r}catch(e){return{}}}},944:(e,t,r)=>{"use strict";function n(e,t){"function"==typeof console.debug&&console.debug("New Relic Warning: https://github.com/newrelic/newrelic-browser-agent/blob/main/docs/warning-codes.md#".concat(e),t)}r.d(t,{R:()=>n})},5284:(e,t,r)=>{"use strict";r.d(t,{t:()=>c,B:()=>s});var n=r(7836),i=r(6154);const o="newrelic";const a=new Set,s={};function c(e,t){const r=n.ee.get(t);s[t]??={},e&&"object"==typeof e&&(a.has(t)||(r.emit("rumresp",[e]),s[t]=e,a.add(t),function(e={}){try{i.gm.dispatchEvent(new CustomEvent(o,{detail:e}))}catch(e){}}({loaded:!0})))}},8990:(e,t,r)=>{"use strict";r.d(t,{I:()=>i});var n=Object.prototype.hasOwnProperty;function i(e,t,r){if(n.call(e,t))return e[t];var i=r();if(Object.defineProperty&&Object.keys)try{return Object.defineProperty(e,t,{value:i,writable:!0,enumerable:!1}),i}catch(e){}return e[t]=i,i}},6389:(e,t,r)=>{"use strict";function n(e,t=500,r={}){const n=r?.leading||!1;let i;return(...r)=>{n&&void 0===i&&(e.apply(this,r),i=setTimeout((()=>{i=clearTimeout(i)}),t)),n||(clearTimeout(i),i=setTimeout((()=>{e.apply(this,r)}),t))}}function i(e){let t=!1;return(...r)=>{t||(t=!0,e.apply(this,r))}}r.d(t,{J:()=>i,s:()=>n})},3304:(e,t,r)=>{"use strict";r.d(t,{A:()=>o});var n=r(7836);const i=()=>{const e=new WeakSet;return(t,r)=>{if("object"==typeof r&&null!==r){if(e.has(r))return;e.add(r)}return r}};function o(e){try{return JSON.stringify(e,i())??""}catch(e){try{n.ee.emit("internal-error",[e])}catch(e){}return""}}},5289:(e,t,r)=>{"use strict";r.d(t,{GG:()=>o,sB:()=>a});var n=r(3878);function i(){return"undefined"==typeof document||"complete"===document.readyState}function o(e,t){if(i())return e();(0,n.sp)("load",e,t)}function a(e){if(i())return e();(0,n.DD)("DOMContentLoaded",e)}},384:(e,t,r)=>{"use strict";r.d(t,{NT:()=>o,US:()=>u,Zm:()=>a,bQ:()=>c,dV:()=>s,nY:()=>d,pV:()=>l});var n=r(6154),i=r(1863);const o={beacon:"bam.nr-data.net",errorBeacon:"bam.nr-data.net"};function a(){return n.gm.NREUM||(n.gm.NREUM={}),void 0===n.gm.newrelic&&(n.gm.newrelic=n.gm.NREUM),n.gm.NREUM}function s(){let e=a();return e.o||(e.o={ST:n.gm.setTimeout,SI:n.gm.setImmediate,CT:n.gm.clearTimeout,XHR:n.gm.XMLHttpRequest,REQ:n.gm.Request,EV:n.gm.Event,PR:n.gm.Promise,MO:n.gm.MutationObserver,FETCH:n.gm.fetch,WS:n.gm.WebSocket}),e}function c(e,t){let r=a();r.initializedAgents??={},t.initializedAt={ms:(0,i.t)(),date:new Date},r.initializedAgents[e]=t}function d(e){let t=a();return t.initializedAgents?.[e]}function u(e,t){a()[e]=t}function l(){return function(){let e=a();const t=e.info||{};e.info={beacon:o.beacon,errorBeacon:o.errorBeacon,...t}}(),function(){let e=a();const t=e.init||{};e.init={...t}}(),s(),function(){let e=a();const t=e.loader_config||{};e.loader_config={...t}}(),a()}},2843:(e,t,r)=>{"use strict";r.d(t,{u:()=>i});var n=r(3878);function i(e,t=!1,r,i){(0,n.DD)("visibilitychange",(function(){if(t)return void("hidden"===document.visibilityState&&e());e(document.visibilityState)}),r,i)}},8139:(e,t,r)=>{"use strict";r.d(t,{u:()=>f});var n=r(7836),i=r(3434),o=r(8990),a=r(6154);const s={},c=a.gm.XMLHttpRequest,d="addEventListener",u="removeEventListener",l="nr@wrapped:".concat(n.P);function f(e){var t=function(e){return(e||n.ee).get("events")}(e);if(s[t.debugId]++)return t;s[t.debugId]=1;var r=(0,i.YM)(t,!0);function f(e){r.inPlace(e,[d,u],"-",g)}function g(e,t){return e[1]}return"getPrototypeOf"in Object&&(a.RI&&h(document,f),h(a.gm,f),h(c.prototype,f)),t.on(d+"-start",(function(e,t){var n=e[1];if(null!==n&&("function"==typeof n||"object"==typeof n)){var i=(0,o.I)(n,l,(function(){var e={object:function(){if("function"!=typeof n.handleEvent)return;return n.handleEvent.apply(n,arguments)},function:n}[typeof n];return e?r(e,"fn-",null,e.name||"anonymous"):n}));this.wrapped=e[1]=i}})),t.on(u+"-start",(function(e){e[1]=this.wrapped||e[1]})),t}function h(e,t,...r){let n=e;for(;"object"==typeof n&&!Object.prototype.hasOwnProperty.call(n,d);)n=Object.getPrototypeOf(n);n&&t(n,...r)}},3434:(e,t,r)=>{"use strict";r.d(t,{YM:()=>c});var n=r(7836),i=r(5607);const o="nr@original:".concat(i.W);var a=Object.prototype.hasOwnProperty,s=!1;function c(e,t){return e||(e=n.ee),r.inPlace=function(e,t,n,i,o){n||(n="");const a="-"===n.charAt(0);for(let s=0;s<t.length;s++){const c=t[s],d=e[c];u(d)||(e[c]=r(d,a?c+n:n,i,c,o))}},r.flag=o,r;function r(t,r,n,s,c){return u(t)?t:(r||(r=""),nrWrapper[o]=t,function(e,t,r){if(Object.defineProperty&&Object.keys)try{return Object.keys(e).forEach((function(r){Object.defineProperty(t,r,{get:function(){return e[r]},set:function(t){return e[r]=t,t}})})),t}catch(e){d([e],r)}for(var n in e)a.call(e,n)&&(t[n]=e[n])}(t,nrWrapper,e),nrWrapper);function nrWrapper(){var o,a,u,l;try{a=this,o=[...arguments],u="function"==typeof n?n(o,a):n||{}}catch(t){d([t,"",[o,a,s],u],e)}i(r+"start",[o,a,s],u,c);try{return l=t.apply(a,o)}catch(e){throw i(r+"err",[o,a,e],u,c),e}finally{i(r+"end",[o,a,l],u,c)}}}function i(r,n,i,o){if(!s||t){var a=s;s=!0;try{e.emit(r,n,i,t,o)}catch(t){d([t,r,n,i],e)}s=a}}}function d(e,t){t||(t=n.ee);try{t.emit("internal-error",e)}catch(e){}}function u(e){return!(e&&"function"==typeof e&&e.apply&&!e[o])}},9300:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.ajax},3333:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,Zp:()=>i,mq:()=>s,nf:()=>a,qN:()=>o});const n=r(860).K7.genericEvents,i=["auxclick","click","copy","keydown","paste","scrollend"],o=["focus","blur"],a=4,s=1e3},6774:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.jserrors},993:(e,t,r)=>{"use strict";r.d(t,{ET:()=>o,TZ:()=>a,p_:()=>i});var n=r(860);const i={ERROR:"ERROR",WARN:"WARN",INFO:"INFO",DEBUG:"DEBUG",TRACE:"TRACE"},o="log",a=n.K7.logging},3785:(e,t,r)=>{"use strict";r.d(t,{R:()=>c,b:()=>d});var n=r(9908),i=r(1863),o=r(860),a=r(3969),s=r(993);function c(e,t,r={},c=s.p_.INFO){(0,n.p)(a.xV,["API/logging/".concat(c.toLowerCase(),"/called")],void 0,o.K7.metrics,e),(0,n.p)(s.ET,[(0,i.t)(),t,r,c],void 0,o.K7.logging,e)}function d(e){return"string"==typeof e&&Object.values(s.p_).some((t=>t===e.toUpperCase().trim()))}},3969:(e,t,r)=>{"use strict";r.d(t,{TZ:()=>n,XG:()=>s,rs:()=>i,xV:()=>a,z_:()=>o});const n=r(860).K7.metrics,i="sm",o="cm",a="storeSupportabilityMetrics",s="storeEventMetrics"},6630:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewEvent},782:(e,t,r)=>{"use strict";r.d(t,{T:()=>n});const n=r(860).K7.pageViewTiming},6344:(e,t,r)=>{"use strict";r.d(t,{BB:()=>u,G4:()=>o,Qb:()=>l,TZ:()=>i,Ug:()=>a,_s:()=>s,bc:()=>d,yP:()=>c});var n=r(2614);const i=r(860).K7.sessionReplay,o={RECORD:"recordReplay",PAUSE:"pauseReplay",REPLAY_RUNNING:"replayRunning",ERROR_DURING_REPLAY:"errorDuringReplay"},a=.12,s={DomContentLoaded:0,Load:1,FullSnapshot:2,IncrementalSnapshot:3,Meta:4,Custom:5},c={[n.g.ERROR]:15e3,[n.g.FULL]:3e5,[n.g.OFF]:0},d={RESET:{message:"Session was reset",sm:"Reset"},IMPORT:{message:"Recorder failed to import",sm:"Import"},TOO_MANY:{message:"429: Too Many Requests",sm:"Too-Many"},TOO_BIG:{message:"Payload was too large",sm:"Too-Big"},CROSS_TAB:{message:"Session Entity was set to OFF on another tab",sm:"Cross-Tab"},ENTITLEMENTS:{message:"Session Replay is not allowed and will not be started",sm:"Entitlement"}},u=5e3,l={API:"api"}},5270:(e,t,r)=>{"use strict";r.d(t,{Aw:()=>c,CT:()=>d,SR:()=>s});var n=r(384),i=r(9417),o=r(7767),a=r(6154);function s(e){return!!(0,n.dV)().o.MO&&(0,o.V)(e)&&!0===(0,i.gD)(e,"session_trace.enabled")}function c(e){return!0===(0,i.gD)(e,"session_replay.preload")&&s(e)}function d(e,t){const r=t.correctAbsoluteTimestamp(e);return{originalTimestamp:e,correctedTimestamp:r,timestampDiff:e-r,originTime:a.WN,correctedOriginTime:t.correctedOriginTime,originTimeDiff:Math.floor(a.WN-t.correctedOriginTime)}}},3738:(e,t,r)=>{"use strict";r.d(t,{He:()=>i,Kp:()=>s,Lc:()=>d,Rz:()=>u,TZ:()=>n,bD:()=>o,d3:()=>a,jx:()=>l,uP:()=>c});const n=r(860).K7.sessionTrace,i="bstResource",o="resource",a="-start",s="-end",c="fn"+a,d="fn"+s,u="pushState",l=1e3},4234:(e,t,r)=>{"use strict";r.d(t,{W:()=>o});var n=r(7836),i=r(1687);class o{constructor(e,t){this.agentIdentifier=e,this.ee=n.ee.get(e),this.featureName=t,this.blocked=!1}deregisterDrain(){(0,i.x3)(this.agentIdentifier,this.featureName)}}},7767:(e,t,r)=>{"use strict";r.d(t,{V:()=>o});var n=r(9417),i=r(6154);const o=e=>i.RI&&!0===(0,n.gD)(e,"privacy.cookies_enabled")},425:(e,t,r)=>{"use strict";r.d(t,{j:()=>P});var n=r(860),i=r(2555),o=r(3371),a=r(9908),s=r(7836),c=r(1687),d=r(5289),u=r(6154),l=r(944),f=r(3969),h=r(384),g=r(6344);const p=["setErrorHandler","finished","addToTrace","addRelease","addPageAction","setCurrentRouteName","setPageViewName","setCustomAttribute","interaction","noticeError","setUserId","setApplicationVersion","start",g.G4.RECORD,g.G4.PAUSE,"log","wrapLogger"],m=["setErrorHandler","finished","addToTrace","addRelease"];var v=r(1863),b=r(2614),y=r(993),R=r(3785),x=r(2646),w=r(3434);function T(e,t,r,n){if("object"!=typeof t||!t||"string"!=typeof r||!r||"function"!=typeof t[r])return(0,l.R)(29);const i=function(e){return(e||s.ee).get("logger")}(e),o=(0,w.YM)(i),a=new x.y(s.P);return a.level=n.level,a.customAttributes=n.customAttributes,o.inPlace(t,[r],"wrap-logger-",a),i}function A(){const e=(0,h.pV)();p.forEach((t=>{e[t]=(...r)=>function(t,...r){let n=[];return Object.values(e.initializedAgents).forEach((e=>{e&&e.api?e.exposed&&e.api[t]&&n.push(e.api[t](...r)):(0,l.R)(38,t)})),n.length>1?n:n[0]}(t,...r)}))}const E={};var S=r(9417),_=r(5603),O=r(5284);const N=e=>{const t=e.startsWith("http");e+="/",r.p=t?e:"https://"+e};let I=!1;function P(e,t={},p,x){let{init:w,info:P,loader_config:j,runtime:C={},exposed:k=!0}=t;C.loaderType=p;const H=(0,h.pV)();P||(w=H.init,P=H.info,j=H.loader_config),(0,S.xN)(e.agentIdentifier,w||{}),(0,_.a)(e.agentIdentifier,j||{}),P.jsAttributes??={},u.bv&&(P.jsAttributes.isWorker=!0),(0,i.x1)(e.agentIdentifier,P);const D=(0,S.D0)(e.agentIdentifier),L=[P.beacon,P.errorBeacon];I||(D.proxy.assets&&(N(D.proxy.assets),L.push(D.proxy.assets)),D.proxy.beacon&&L.push(D.proxy.beacon),A(),(0,h.US)("activatedFeatures",O.B),e.runSoftNavOverSpa&&=!0===D.soft_navigations.enabled&&D.feature_flags.includes("soft_nav")),C.denyList=[...D.ajax.deny_list||[],...D.ajax.block_internal?L:[]],C.ptid=e.agentIdentifier,(0,o.V)(e.agentIdentifier,C),e.ee=s.ee.get(e.agentIdentifier),void 0===e.api&&(e.api=function(e,t,h=!1){t||(0,c.Ak)(e,"api");const p={};var x=s.ee.get(e),w=x.get("tracer");E[e]=b.g.OFF,x.on(g.G4.REPLAY_RUNNING,(t=>{E[e]=t}));var A="api-",S=A+"ixn-";function _(t,r,n,o){const a=(0,i.Vp)(e);return null===r?delete a.jsAttributes[t]:(0,i.x1)(e,{...a,jsAttributes:{...a.jsAttributes,[t]:r}}),I(A,n,!0,o||null===r?"session":void 0)(t,r)}function O(){}p.log=function(e,{customAttributes:t={},level:r=y.p_.INFO}={}){(0,a.p)(f.xV,["API/log/called"],void 0,n.K7.metrics,x),(0,R.R)(x,e,t,r)},p.wrapLogger=(e,t,{customAttributes:r={},level:i=y.p_.INFO}={})=>{(0,a.p)(f.xV,["API/wrapLogger/called"],void 0,n.K7.metrics,x),T(x,e,t,{customAttributes:r,level:i})},m.forEach((e=>{p[e]=I(A,e,!0,"api")})),p.addPageAction=I(A,"addPageAction",!0,n.K7.genericEvents),p.setPageViewName=function(t,r){if("string"==typeof t)return"/"!==t.charAt(0)&&(t="/"+t),(0,o.f)(e).customTransaction=(r||"http://custom.transaction")+t,I(A,"setPageViewName",!0)()},p.setCustomAttribute=function(e,t,r=!1){if("string"==typeof e){if(["string","number","boolean"].includes(typeof t)||null===t)return _(e,t,"setCustomAttribute",r);(0,l.R)(40,typeof t)}else(0,l.R)(39,typeof e)},p.setUserId=function(e){if("string"==typeof e||null===e)return _("enduser.id",e,"setUserId",!0);(0,l.R)(41,typeof e)},p.setApplicationVersion=function(e){if("string"==typeof e||null===e)return _("application.version",e,"setApplicationVersion",!1);(0,l.R)(42,typeof e)},p.start=()=>{try{(0,a.p)(f.xV,["API/start/called"],void 0,n.K7.metrics,x),x.emit("manual-start-all")}catch(e){(0,l.R)(23,e)}},p[g.G4.RECORD]=function(){(0,a.p)(f.xV,["API/recordReplay/called"],void 0,n.K7.metrics,x),(0,a.p)(g.G4.RECORD,[],void 0,n.K7.sessionReplay,x)},p[g.G4.PAUSE]=function(){(0,a.p)(f.xV,["API/pauseReplay/called"],void 0,n.K7.metrics,x),(0,a.p)(g.G4.PAUSE,[],void 0,n.K7.sessionReplay,x)},p.interaction=function(e){return(new O).get("object"==typeof e?e:{})};const N=O.prototype={createTracer:function(e,t){var r={},i=this,o="function"==typeof t;return(0,a.p)(f.xV,["API/createTracer/called"],void 0,n.K7.metrics,x),h||(0,a.p)(S+"tracer",[(0,v.t)(),e,r],i,n.K7.spa,x),function(){if(w.emit((o?"":"no-")+"fn-start",[(0,v.t)(),i,o],r),o)try{return t.apply(this,arguments)}catch(e){const t="string"==typeof e?new Error(e):e;throw w.emit("fn-err",[arguments,this,t],r),t}finally{w.emit("fn-end",[(0,v.t)()],r)}}}};function I(e,t,r,i){return function(){return(0,a.p)(f.xV,["API/"+t+"/called"],void 0,n.K7.metrics,x),i&&(0,a.p)(e+t,[(0,v.t)(),...arguments],r?null:this,i,x),r?void 0:this}}function P(){r.e(891).then(r.bind(r,8778)).then((({setAPI:t})=>{t(e),(0,c.Ze)(e,"api")})).catch((e=>{(0,l.R)(27,e),x.abort()}))}return["actionText","setName","setAttribute","save","ignore","onEnd","getContext","end","get"].forEach((e=>{N[e]=I(S,e,void 0,h?n.K7.softNav:n.K7.spa)})),p.setCurrentRouteName=h?I(S,"routeName",void 0,n.K7.softNav):I(A,"routeName",!0,n.K7.spa),p.noticeError=function(t,r){"string"==typeof t&&(t=new Error(t)),(0,a.p)(f.xV,["API/noticeError/called"],void 0,n.K7.metrics,x),(0,a.p)("err",[t,(0,v.t)(),!1,r,!!E[e]],void 0,n.K7.jserrors,x)},u.RI?(0,d.GG)((()=>P()),!0):P(),p}(e.agentIdentifier,x,e.runSoftNavOverSpa)),void 0===e.exposed&&(e.exposed=k),I=!0}},8374:(e,t,r)=>{r.nc=(()=>{try{return document?.currentScript?.nonce}catch(e){}return""})()},860:(e,t,r)=>{"use strict";r.d(t,{$J:()=>o,K7:()=>n,P3:()=>i});const n={ajax:"ajax",genericEvents:"generic_events",jserrors:"jserrors",logging:"logging",metrics:"metrics",pageAction:"page_action",pageViewEvent:"page_view_event",pageViewTiming:"page_view_timing",sessionReplay:"session_replay",sessionTrace:"session_trace",softNav:"soft_navigations",spa:"spa"},i={[n.pageViewEvent]:1,[n.pageViewTiming]:2,[n.metrics]:3,[n.jserrors]:4,[n.spa]:5,[n.ajax]:6,[n.sessionTrace]:7,[n.softNav]:8,[n.sessionReplay]:9,[n.logging]:10,[n.genericEvents]:11},o={[n.pageViewTiming]:"events",[n.ajax]:"events",[n.spa]:"events",[n.softNav]:"events",[n.metrics]:"jserrors",[n.jserrors]:"jserrors",[n.sessionTrace]:"browser/blobs",[n.sessionReplay]:"browser/blobs",[n.logging]:"browser/logs",[n.genericEvents]:"ins"}}},n={};function i(e){var t=n[e];if(void 0!==t)return t.exports;var o=n[e]={exports:{}};return r[e](o,o.exports,i),o.exports}i.m=r,i.d=(e,t)=>{for(var r in t)i.o(t,r)&&!i.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})},i.f={},i.e=e=>Promise.all(Object.keys(i.f).reduce(((t,r)=>(i.f[r](e,t),t)),[])),i.u=e=>({95:"nr-full-compressor",222:"nr-full-recorder",891:"nr-full"}[e]+"-1.274.0.min.js"),i.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),e={},t="NRBA-1.274.0.PROD:",i.l=(r,n,o,a)=>{if(e[r])e[r].push(n);else{var s,c;if(void 0!==o)for(var d=document.getElementsByTagName("script"),u=0;u<d.length;u++){var l=d[u];if(l.getAttribute("src")==r||l.getAttribute("data-webpack")==t+o){s=l;break}}if(!s){c=!0;var f={891:"sha512-Sx2xJQrHp2m/Ngn/ZcfBCUwNr2Xy/C5urYtWpfm3bWpil4spXOQGTtNwIfF5HvPGioGASn9QTyE4Z+zC7r7wcg==",222:"sha512-hMte3OWgwwYeisSiD7WCIx/6tT16zLaPjag9uF4tIZp7ybOvrJKbeyzhe4fz1tDbkdcdOMm8dvgPPLBatSAGeA==",95:"sha512-MPaT9dkHv16XzwEUVZPyqpN1do/Er1XFAZoIAPYWylmv+iGIThqN+GwQq27pUyAX7sNXVJQVZezH96p53Ks3Pg=="};(s=document.createElement("script")).charset="utf-8",s.timeout=120,i.nc&&s.setAttribute("nonce",i.nc),s.setAttribute("data-webpack",t+o),s.src=r,0!==s.src.indexOf(window.location.origin+"/")&&(s.crossOrigin="anonymous"),f[a]&&(s.integrity=f[a])}e[r]=[n];var h=(t,n)=>{s.onerror=s.onload=null,clearTimeout(g);var i=e[r];if(delete e[r],s.parentNode&&s.parentNode.removeChild(s),i&&i.forEach((e=>e(n))),t)return t(n)},g=setTimeout(h.bind(null,void 0,{type:"timeout",target:s}),12e4);s.onerror=h.bind(null,s.onerror),s.onload=h.bind(null,s.onload),c&&document.head.appendChild(s)}},i.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})},i.p="https://js-agent.newrelic.com/",(()=>{var e={959:0,85:0};i.f.j=(t,r)=>{var n=i.o(e,t)?e[t]:void 0;if(0!==n)if(n)r.push(n[2]);else{var o=new Promise(((r,i)=>n=e[t]=[r,i]));r.push(n[2]=o);var a=i.p+i.u(t),s=new Error;i.l(a,(r=>{if(i.o(e,t)&&(0!==(n=e[t])&&(e[t]=void 0),n)){var o=r&&("load"===r.type?"missing":r.type),a=r&&r.target&&r.target.src;s.message="Loading chunk "+t+" failed.\n("+o+": "+a+")",s.name="ChunkLoadError",s.type=o,s.request=a,n[1](s)}}),"chunk-"+t,t)}};var t=(t,r)=>{var n,o,[a,s,c]=r,d=0;if(a.some((t=>0!==e[t]))){for(n in s)i.o(s,n)&&(i.m[n]=s[n]);if(c)c(i)}for(t&&t(r);d<a.length;d++)o=a[d],i.o(e,o)&&e[o]&&e[o][0](),e[o]=0},r=self["webpackChunk:NRBA-1.274.0.PROD"]=self["webpackChunk:NRBA-1.274.0.PROD"]||[];r.forEach(t.bind(null,0)),r.push=t.bind(null,r.push.bind(r))})(),(()=>{"use strict";i(8374);var e=i(944),t=i(6344),r=i(9566);class n{agentIdentifier;constructor(e=(0,r.LA)(16)){this.agentIdentifier=e}#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}addPageAction(e,t){return this.#e("addPageAction",e,t)}setPageViewName(e,t){return this.#e("setPageViewName",e,t)}setCustomAttribute(e,t,r){return this.#e("setCustomAttribute",e,t,r)}noticeError(e,t){return this.#e("noticeError",e,t)}setUserId(e){return this.#e("setUserId",e)}setApplicationVersion(e){return this.#e("setApplicationVersion",e)}setErrorHandler(e){return this.#e("setErrorHandler",e)}addRelease(e,t){return this.#e("addRelease",e,t)}log(e,t){return this.#e("log",e,t)}}class o extends n{#e(t,...r){if("function"==typeof this.api?.[t])return this.api[t](...r);(0,e.R)(35,t)}start(){return this.#e("start")}finished(e){return this.#e("finished",e)}recordReplay(){return this.#e(t.G4.RECORD)}pauseReplay(){return this.#e(t.G4.PAUSE)}addToTrace(e){return this.#e("addToTrace",e)}setCurrentRouteName(e){return this.#e("setCurrentRouteName",e)}interaction(){return this.#e("interaction")}wrapLogger(e,t,r){return this.#e("wrapLogger",e,t,r)}}var a=i(860),s=i(9417);const c=Object.values(a.K7);function d(e){const t={};return c.forEach((r=>{t[r]=function(e,t){return!0===(0,s.gD)(t,"".concat(e,".enabled"))}(r,e)})),t}var u=i(425);var l=i(1687),f=i(4234),h=i(5289),g=i(6154),p=i(5270),m=i(7767),v=i(6389);class b extends f.W{constructor(e,t,r=!0){super(e.agentIdentifier,t),this.auto=r,this.abortHandler=void 0,this.featAggregate=void 0,this.onAggregateImported=void 0,!1===e.init[this.featureName].autoStart&&(this.auto=!1),this.auto?(0,l.Ak)(e.agentIdentifier,t):this.ee.on("manual-start-all",(0,v.J)((()=>{(0,l.Ak)(e.agentIdentifier,this.featureName),this.auto=!0,this.importAggregator(e)})))}importAggregator(t,r={}){if(this.featAggregate||!this.auto)return;let n;this.onAggregateImported=new Promise((e=>{n=e}));const o=async()=>{let o;try{if((0,m.V)(this.agentIdentifier)){const{setupAgentSession:e}=await i.e(891).then(i.bind(i,6526));o=e(t)}}catch(t){(0,e.R)(20,t),this.ee.emit("internal-error",[t]),this.featureName===a.K7.sessionReplay&&this.abortHandler?.()}try{if(t.sharedAggregator)await t.sharedAggregator;else{t.sharedAggregator=i.e(891).then(i.bind(i,9337));const{EventAggregator:e}=await t.sharedAggregator;t.sharedAggregator=new e}if(!this.#t(this.featureName,o))return(0,l.Ze)(this.agentIdentifier,this.featureName),void n(!1);const{lazyFeatureLoader:e}=await i.e(891).then(i.bind(i,6103)),{Aggregate:a}=await e(this.featureName,"aggregate");this.featAggregate=new a(t,r),n(!0)}catch(t){(0,e.R)(34,t),this.abortHandler?.(),(0,l.Ze)(this.agentIdentifier,this.featureName,!0),n(!1),this.ee&&this.ee.abort()}};g.RI?(0,h.GG)((()=>o()),!0):o()}#t(e,t){switch(e){case a.K7.sessionReplay:return(0,p.SR)(this.agentIdentifier)&&!!t;case a.K7.sessionTrace:return!!t;default:return!0}}}var y=i(6630);class R extends b{static featureName=y.T;constructor(e,t=!0){super(e,y.T,t),this.importAggregator(e)}}var x=i(384);var w=i(9908),T=i(2843),A=i(3878),E=i(782),S=i(1863);class _ extends b{static featureName=E.T;constructor(e,t=!0){super(e,E.T,t),g.RI&&((0,T.u)((()=>(0,w.p)("docHidden",[(0,S.t)()],void 0,E.T,this.ee)),!0),(0,A.sp)("pagehide",(()=>(0,w.p)("winPagehide",[(0,S.t)()],void 0,E.T,this.ee))),this.importAggregator(e))}}var O=i(3969);class N extends b{static featureName=O.TZ;constructor(e,t=!0){super(e,O.TZ,t),this.importAggregator(e)}}var I=i(6774),P=i(3304);class j{constructor(e,t,r,n,i){this.name="UncaughtError",this.message="string"==typeof e?e:(0,P.A)(e),this.sourceURL=t,this.line=r,this.column=n,this.__newrelic=i}}function C(e){return D(e)?e:new j(void 0!==e?.message?e.message:e,e?.filename||e?.sourceURL,e?.lineno||e?.line,e?.colno||e?.col,e?.__newrelic)}function k(e){const t="Unhandled Promise Rejection";if(!e?.reason)return;if(D(e.reason))try{return e.reason.message=t+": "+e.reason.message,C(e.reason)}catch(t){return C(e.reason)}const r=C(e.reason);return r.message=t+": "+r?.message,r}function H(e){if(e.error instanceof SyntaxError&&!/:\d+$/.test(e.error.stack?.trim())){const t=new j(e.message,e.filename,e.lineno,e.colno,e.error.__newrelic);return t.name=SyntaxError.name,t}return D(e.error)?e.error:C(e)}function D(e){return e instanceof Error&&!!e.stack}class L extends b{static featureName=I.T;#r=!1;constructor(e,r=!0){super(e,I.T,r);try{this.removeOnAbort=new AbortController}catch(e){}this.ee.on("internal-error",(e=>{this.abortHandler&&(0,w.p)("ierr",[C(e),(0,S.t)(),!0,{},this.#r],void 0,this.featureName,this.ee)})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.#r=e})),g.gm.addEventListener("unhandledrejection",(e=>{this.abortHandler&&(0,w.p)("err",[k(e),(0,S.t)(),!1,{unhandledPromiseRejection:1},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),g.gm.addEventListener("error",(e=>{this.abortHandler&&(0,w.p)("err",[H(e),(0,S.t)(),!1,{},this.#r],void 0,this.featureName,this.ee)}),(0,A.jT)(!1,this.removeOnAbort?.signal)),this.abortHandler=this.#n,this.importAggregator(e)}#n(){this.removeOnAbort?.abort(),this.abortHandler=void 0}}var K=i(8990);let M=1;const U="nr@id";function V(e){const t=typeof e;return!e||"object"!==t&&"function"!==t?-1:e===g.gm?0:(0,K.I)(e,U,(function(){return M++}))}function G(e){if("string"==typeof e&&e.length)return e.length;if("object"==typeof e){if("undefined"!=typeof ArrayBuffer&&e instanceof ArrayBuffer&&e.byteLength)return e.byteLength;if("undefined"!=typeof Blob&&e instanceof Blob&&e.size)return e.size;if(!("undefined"!=typeof FormData&&e instanceof FormData))try{return(0,P.A)(e).length}catch(e){return}}}var F=i(8139),B=i(7836),W=i(3434);const z={},q=["open","send"];function Z(t){var r=t||B.ee;const n=function(e){return(e||B.ee).get("xhr")}(r);if(z[n.debugId]++)return n;z[n.debugId]=1,(0,F.u)(r);var i=(0,W.YM)(n),o=g.gm.XMLHttpRequest,a=g.gm.MutationObserver,s=g.gm.Promise,c=g.gm.setInterval,d="readystatechange",u=["onload","onerror","onabort","onloadstart","onloadend","onprogress","ontimeout"],l=[],f=g.gm.XMLHttpRequest=function(t){const r=new o(t),a=n.context(r);try{n.emit("new-xhr",[r],a),r.addEventListener(d,(s=a,function(){var e=this;e.readyState>3&&!s.resolved&&(s.resolved=!0,n.emit("xhr-resolved",[],e)),i.inPlace(e,u,"fn-",y)}),(0,A.jT)(!1))}catch(t){(0,e.R)(15,t);try{n.emit("internal-error",[t])}catch(e){}}var s;return r};function h(e,t){i.inPlace(t,["onreadystatechange"],"fn-",y)}if(function(e,t){for(var r in e)t[r]=e[r]}(o,f),f.prototype=o.prototype,i.inPlace(f.prototype,q,"-xhr-",y),n.on("send-xhr-start",(function(e,t){h(e,t),function(e){l.push(e),a&&(p?p.then(b):c?c(b):(m=-m,v.data=m))}(t)})),n.on("open-xhr-start",h),a){var p=s&&s.resolve();if(!c&&!s){var m=1,v=document.createTextNode(m);new a(b).observe(v,{characterData:!0})}}else r.on("fn-end",(function(e){e[0]&&e[0].type===d||b()}));function b(){for(var e=0;e<l.length;e++)h(0,l[e]);l.length&&(l=[])}function y(e,t){return t}return n}var Y="fetch-",X=Y+"body-",Q=["arrayBuffer","blob","json","text","formData"],J=g.gm.Request,ee=g.gm.Response,te="prototype";const re={};function ne(e){const t=function(e){return(e||B.ee).get("fetch")}(e);if(!(J&&ee&&g.gm.fetch))return t;if(re[t.debugId]++)return t;function r(e,r,n){var i=e[r];"function"==typeof i&&(e[r]=function(){var e,r=[...arguments],o={};t.emit(n+"before-start",[r],o),o[B.P]&&o[B.P].dt&&(e=o[B.P].dt);var a=i.apply(this,r);return t.emit(n+"start",[r,e],a),a.then((function(e){return t.emit(n+"end",[null,e],a),e}),(function(e){throw t.emit(n+"end",[e],a),e}))})}return re[t.debugId]=1,Q.forEach((e=>{r(J[te],e,X),r(ee[te],e,X)})),r(g.gm,"fetch",Y),t.on(Y+"end",(function(e,r){var n=this;if(r){var i=r.headers.get("content-length");null!==i&&(n.rxSize=i),t.emit(Y+"done",[null,r],n)}else t.emit(Y+"done",[e],n)})),t}var ie=i(7485),oe=i(5603);class ae{constructor(e){this.agentIdentifier=e}generateTracePayload(e){if(!this.shouldGenerateTrace(e))return null;var t=(0,oe.o)(this.agentIdentifier);if(!t)return null;var n=(t.accountID||"").toString()||null,i=(t.agentID||"").toString()||null,o=(t.trustKey||"").toString()||null;if(!n||!i)return null;var a=(0,r.ZF)(),s=(0,r.el)(),c=Date.now(),d={spanId:a,traceId:s,timestamp:c};return(e.sameOrigin||this.isAllowedOrigin(e)&&this.useTraceContextHeadersForCors())&&(d.traceContextParentHeader=this.generateTraceContextParentHeader(a,s),d.traceContextStateHeader=this.generateTraceContextStateHeader(a,c,n,i,o)),(e.sameOrigin&&!this.excludeNewrelicHeader()||!e.sameOrigin&&this.isAllowedOrigin(e)&&this.useNewrelicHeaderForCors())&&(d.newrelicHeader=this.generateTraceHeader(a,s,c,n,i,o)),d}generateTraceContextParentHeader(e,t){return"00-"+t+"-"+e+"-01"}generateTraceContextStateHeader(e,t,r,n,i){return i+"@nr=0-1-"+r+"-"+n+"-"+e+"----"+t}generateTraceHeader(e,t,r,n,i,o){if(!("function"==typeof g.gm?.btoa))return null;var a={v:[0,1],d:{ty:"Browser",ac:n,ap:i,id:e,tr:t,ti:r}};return o&&n!==o&&(a.d.tk=o),btoa((0,P.A)(a))}shouldGenerateTrace(e){return this.isDtEnabled()&&this.isAllowedOrigin(e)}isAllowedOrigin(e){var t=!1,r={};if((0,s.gD)(this.agentIdentifier,"distributed_tracing")&&(r=(0,s.D0)(this.agentIdentifier).distributed_tracing),e.sameOrigin)t=!0;else if(r.allowed_origins instanceof Array)for(var n=0;n<r.allowed_origins.length;n++){var i=(0,ie.D)(r.allowed_origins[n]);if(e.hostname===i.hostname&&e.protocol===i.protocol&&e.port===i.port){t=!0;break}}return t}isDtEnabled(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.enabled}excludeNewrelicHeader(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.exclude_newrelic_header}useNewrelicHeaderForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!1!==e.cors_use_newrelic_header}useTraceContextHeadersForCors(){var e=(0,s.gD)(this.agentIdentifier,"distributed_tracing");return!!e&&!!e.cors_use_tracecontext_headers}}var se=i(9300),ce=i(7295),de=["load","error","abort","timeout"],ue=de.length,le=(0,x.dV)().o.REQ,fe=(0,x.dV)().o.XHR;class he extends b{static featureName=se.T;constructor(e,t=!0){super(e,se.T,t),this.dt=new ae(e.agentIdentifier),this.handler=(e,t,r,n)=>(0,w.p)(e,t,r,n,this.ee);try{const e={xmlhttprequest:"xhr",fetch:"fetch",beacon:"beacon"};g.gm?.performance?.getEntriesByType("resource").forEach((t=>{if(t.initiatorType in e&&0!==t.responseStatus){const r={status:t.responseStatus},n={rxSize:t.transferSize,duration:Math.floor(t.duration),cbTime:0};ge(r,t.name),this.handler("xhr",[r,n,t.startTime,t.responseEnd,e[t.initiatorType]],void 0,a.K7.ajax)}}))}catch(e){}ne(this.ee),Z(this.ee),function(e,t,r,n){function i(e){var t=this;t.totalCbs=0,t.called=0,t.cbTime=0,t.end=x,t.ended=!1,t.xhrGuids={},t.lastSize=null,t.loadCaptureCalled=!1,t.params=this.params||{},t.metrics=this.metrics||{},e.addEventListener("load",(function(r){T(t,e)}),(0,A.jT)(!1)),g.lR||e.addEventListener("progress",(function(e){t.lastSize=e.loaded}),(0,A.jT)(!1))}function o(e){this.params={method:e[0]},ge(this,e[1]),this.metrics={}}function s(t,r){e.loader_config.xpid&&this.sameOrigin&&r.setRequestHeader("X-NewRelic-ID",e.loader_config.xpid);var i=n.generateTracePayload(this.parsedOrigin);if(i){var o=!1;i.newrelicHeader&&(r.setRequestHeader("newrelic",i.newrelicHeader),o=!0),i.traceContextParentHeader&&(r.setRequestHeader("traceparent",i.traceContextParentHeader),i.traceContextStateHeader&&r.setRequestHeader("tracestate",i.traceContextStateHeader),o=!0),o&&(this.dt=i)}}function c(e,r){var n=this.metrics,i=e[0],o=this;if(n&&i){var a=G(i);a&&(n.txSize=a)}this.startTime=(0,S.t)(),this.body=i,this.listener=function(e){try{"abort"!==e.type||o.loadCaptureCalled||(o.params.aborted=!0),("load"!==e.type||o.called===o.totalCbs&&(o.onloadCalled||"function"!=typeof r.onload)&&"function"==typeof o.end)&&o.end(r)}catch(e){try{t.emit("internal-error",[e])}catch(e){}}};for(var s=0;s<ue;s++)r.addEventListener(de[s],this.listener,(0,A.jT)(!1))}function d(e,t,r){this.cbTime+=e,t?this.onloadCalled=!0:this.called+=1,this.called!==this.totalCbs||!this.onloadCalled&&"function"==typeof r.onload||"function"!=typeof this.end||this.end(r)}function u(e,t){var r=""+V(e)+!!t;this.xhrGuids&&!this.xhrGuids[r]&&(this.xhrGuids[r]=!0,this.totalCbs+=1)}function l(e,t){var r=""+V(e)+!!t;this.xhrGuids&&this.xhrGuids[r]&&(delete this.xhrGuids[r],this.totalCbs-=1)}function f(){this.endTime=(0,S.t)()}function h(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-added",[e[1],e[2]],r)}function p(e,r){r instanceof fe&&"load"===e[0]&&t.emit("xhr-load-removed",[e[1],e[2]],r)}function m(e,t,r){t instanceof fe&&("onload"===r&&(this.onload=!0),("load"===(e[0]&&e[0].type)||this.onload)&&(this.xhrCbStart=(0,S.t)()))}function v(e,r){this.xhrCbStart&&t.emit("xhr-cb-time",[(0,S.t)()-this.xhrCbStart,this.onload,r],r)}function b(e){var t,r=e[1]||{};if("string"==typeof e[0]?0===(t=e[0]).length&&g.RI&&(t=""+g.gm.location.href):e[0]&&e[0].url?t=e[0].url:g.gm?.URL&&e[0]&&e[0]instanceof URL?t=e[0].href:"function"==typeof e[0].toString&&(t=e[0].toString()),"string"==typeof t&&0!==t.length){t&&(this.parsedOrigin=(0,ie.D)(t),this.sameOrigin=this.parsedOrigin.sameOrigin);var i=n.generateTracePayload(this.parsedOrigin);if(i&&(i.newrelicHeader||i.traceContextParentHeader))if(e[0]&&e[0].headers)s(e[0].headers,i)&&(this.dt=i);else{var o={};for(var a in r)o[a]=r[a];o.headers=new Headers(r.headers||{}),s(o.headers,i)&&(this.dt=i),e.length>1?e[1]=o:e.push(o)}}function s(e,t){var r=!1;return t.newrelicHeader&&(e.set("newrelic",t.newrelicHeader),r=!0),t.traceContextParentHeader&&(e.set("traceparent",t.traceContextParentHeader),t.traceContextStateHeader&&e.set("tracestate",t.traceContextStateHeader),r=!0),r}}function y(e,t){this.params={},this.metrics={},this.startTime=(0,S.t)(),this.dt=t,e.length>=1&&(this.target=e[0]),e.length>=2&&(this.opts=e[1]);var r,n=this.opts||{},i=this.target;"string"==typeof i?r=i:"object"==typeof i&&i instanceof le?r=i.url:g.gm?.URL&&"object"==typeof i&&i instanceof URL&&(r=i.href),ge(this,r);var o=(""+(i&&i instanceof le&&i.method||n.method||"GET")).toUpperCase();this.params.method=o,this.body=n.body,this.txSize=G(n.body)||0}function R(e,t){if(this.endTime=(0,S.t)(),this.params||(this.params={}),(0,ce.iW)(this.params))return;let n;this.params.status=t?t.status:0,"string"==typeof this.rxSize&&this.rxSize.length>0&&(n=+this.rxSize);const i={txSize:this.txSize,rxSize:n,duration:(0,S.t)()-this.startTime};r("xhr",[this.params,i,this.startTime,this.endTime,"fetch"],this,a.K7.ajax)}function x(e){const t=this.params,n=this.metrics;if(!this.ended){this.ended=!0;for(let t=0;t<ue;t++)e.removeEventListener(de[t],this.listener,!1);t.aborted||(0,ce.iW)(t)||(n.duration=(0,S.t)()-this.startTime,this.loadCazptureCalled||4!==e.readyState?null==t.status&&(t.status=0):T(this,e),n.cbTime=this.cbTime,r("xhr",[t,n,this.startTime,this.endTime,"xhr"],this,a.K7.ajax))}}function T(e,r){e.params.status=r.status;var n=function(e,t){var r=e.responseType;return"json"===r&&null!==t?t:"arraybuffer"===r||"blob"===r||"json"===r?G(e.response):"text"===r||""===r||void 0===r?G(e.responseText):void 0}(r,e.lastSize);if(n&&(e.metrics.rxSize=n),e.sameOrigin){var i=r.getResponseHeader("X-NewRelic-App-Data");i&&((0,w.p)(O.rs,["Ajax/CrossApplicationTracing/Header/Seen"],void 0,a.K7.metrics,t),e.params.cat=i.split(", ").pop())}e.loadCaptureCalled=!0}t.on("new-xhr",i),t.on("open-xhr-start",o),t.on("open-xhr-end",s),t.on("send-xhr-start",c),t.on("xhr-cb-time",d),t.on("xhr-load-added",u),t.on("xhr-load-removed",l),t.on("xhr-resolved",f),t.on("addEventListener-end",h),t.on("removeEventListener-end",p),t.on("fn-end",v),t.on("fetch-before-start",b),t.on("fetch-start",y),t.on("fn-start",m),t.on("fetch-done",R)}(e,this.ee,this.handler,this.dt),this.importAggregator(e)}}function ge(e,t){var r=(0,ie.D)(t),n=e.params||e;n.hostname=r.hostname,n.port=r.port,n.protocol=r.protocol,n.host=r.hostname+":"+r.port,n.pathname=r.pathname,e.parsedOrigin=r,e.sameOrigin=r.sameOrigin}const pe={},me=["pushState","replaceState"];function ve(e){const t=function(e){return(e||B.ee).get("history")}(e);return!g.RI||pe[t.debugId]++||(pe[t.debugId]=1,(0,W.YM)(t).inPlace(window.history,me,"-")),t}var be=i(3738);const{He:ye,bD:Re,d3:xe,Kp:we,TZ:Te,Lc:Ae,uP:Ee,Rz:Se}=be;class _e extends b{static featureName=Te;constructor(e,t=!0){super(e,Te,t);if(!(0,m.V)(this.agentIdentifier))return void this.deregisterDrain();const r=this.ee;let n;ve(r),this.eventsEE=(0,F.u)(r),this.eventsEE.on(Ee,(function(e,t){this.bstStart=(0,S.t)()})),this.eventsEE.on(Ae,(function(e,t){(0,w.p)("bst",[e[0],t,this.bstStart,(0,S.t)()],void 0,a.K7.sessionTrace,r)})),r.on(Se+xe,(function(e){this.time=(0,S.t)(),this.startPath=location.pathname+location.hash})),r.on(Se+we,(function(e){(0,w.p)("bstHist",[location.pathname+location.hash,this.startPath,this.time],void 0,a.K7.sessionTrace,r)}));try{n=new PerformanceObserver((e=>{const t=e.getEntries();(0,w.p)(ye,[t],void 0,a.K7.sessionTrace,r)})),n.observe({type:Re,buffered:!0})}catch(e){}this.importAggregator(e,{resourceObserver:n})}}var Oe=i(2614);class Ne extends b{static featureName=t.TZ;#i;#o;constructor(e,r=!0){let n;super(e,t.TZ,r),this.replayRunning=!1,this.#o=e;try{n=JSON.parse(localStorage.getItem("".concat(Oe.H3,"_").concat(Oe.uh)))}catch(e){}(0,p.SR)(e.agentIdentifier)&&this.ee.on(t.G4.RECORD,(()=>this.#a())),this.#s(n)?(this.#i=n?.sessionReplayMode,this.#c()):this.importAggregator(e),this.ee.on("err",(e=>{this.replayRunning&&(this.errorNoticed=!0,(0,w.p)(t.G4.ERROR_DURING_REPLAY,[e],void 0,this.featureName,this.ee))})),this.ee.on(t.G4.REPLAY_RUNNING,(e=>{this.replayRunning=e}))}#s(e){return e&&(e.sessionReplayMode===Oe.g.FULL||e.sessionReplayMode===Oe.g.ERROR)||(0,p.Aw)(this.agentIdentifier)}#d=!1;async#c(e){if(!this.#d){this.#d=!0;try{const{Recorder:t}=await Promise.all([i.e(891),i.e(222)]).then(i.bind(i,8589));this.recorder??=new t({mode:this.#i,agentIdentifier:this.agentIdentifier,trigger:e,ee:this.ee}),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording}catch(e){}this.importAggregator(this.#o,{recorder:this.recorder,errorNoticed:this.errorNoticed})}}#a(){this.featAggregate?this.featAggregate.mode!==Oe.g.FULL&&this.featAggregate.initializeRecording(Oe.g.FULL,!0):(this.#i=Oe.g.FULL,this.#c(t.Qb.API),this.recorder&&this.recorder.parent.mode!==Oe.g.FULL&&(this.recorder.parent.mode=Oe.g.FULL,this.recorder.stopRecording(),this.recorder.startRecording(),this.abortHandler=this.recorder.stopRecording))}}var Ie=i(3333);class Pe extends b{static featureName=Ie.TZ;constructor(e,t=!0){super(e,Ie.TZ,t);const r=[e.init.page_action.enabled,e.init.performance.capture_marks,e.init.performance.capture_measures,e.init.user_actions.enabled];g.RI&&e.init.user_actions.enabled&&(Ie.Zp.forEach((e=>(0,A.sp)(e,(e=>(0,w.p)("ua",[e],void 0,this.featureName,this.ee)),!0))),Ie.qN.forEach((e=>(0,A.sp)(e,(e=>(0,w.p)("ua",[e],void 0,this.featureName,this.ee)))))),r.some((e=>e))?this.importAggregator(e):this.deregisterDrain()}}var je=i(993),Ce=i(3785);class ke extends b{static featureName=je.TZ;constructor(e,t=!0){super(e,je.TZ,t);const r=this.ee;this.ee.on("wrap-logger-end",(function([e]){const{level:t,customAttributes:n}=this;(0,Ce.R)(r,e,n,t)})),this.importAggregator(e)}}new class extends o{constructor(t,r){super(r),g.gm?(this.features={},(0,x.bQ)(this.agentIdentifier,this),this.desiredFeatures=new Set(t.features||[]),this.desiredFeatures.add(R),this.runSoftNavOverSpa=[...this.desiredFeatures].some((e=>e.featureName===a.K7.softNav)),(0,u.j)(this,t,t.loaderType||"agent"),this.run()):(0,e.R)(21)}get config(){return{info:this.info,init:this.init,loader_config:this.loader_config,runtime:this.runtime}}run(){try{const t=d(this.agentIdentifier),r=[...this.desiredFeatures];r.sort(((e,t)=>a.P3[e.featureName]-a.P3[t.featureName])),r.forEach((r=>{if(!t[r.featureName]&&r.featureName!==a.K7.pageViewEvent)return;if(this.runSoftNavOverSpa&&r.featureName===a.K7.spa)return;if(!this.runSoftNavOverSpa&&r.featureName===a.K7.softNav)return;const n=function(e){switch(e){case a.K7.ajax:return[a.K7.jserrors];case a.K7.sessionTrace:return[a.K7.ajax,a.K7.pageViewEvent];case a.K7.sessionReplay:return[a.K7.sessionTrace];case a.K7.pageViewTiming:return[a.K7.pageViewEvent];default:return[]}}(r.featureName).filter((e=>!(e in this.features)));n.length>0&&(0,e.R)(36,{targetFeature:r.featureName,missingDependencies:n}),this.features[r.featureName]=new r(this)}))}catch(t){(0,e.R)(22,t);for(const e in this.features)this.features[e].abortHandler?.();const r=(0,x.Zm)();delete r.initializedAgents[this.agentIdentifier]?.api,delete r.initializedAgents[this.agentIdentifier]?.features,delete this.sharedAggregator;return r.ee.get(this.agentIdentifier).abort(),!1}}}({features:[R,_,_e,Ne,he,N,L,Pe,ke],loaderType:"pro"})})()})();</script> <link rel="profile" href="http://www.w3.org/1999/xhtml/vocab" /> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <meta name="keywords" content="" /> <link rel="canonical" href="https://www.tocris.com/literature/literature-request/234525" /> <title>Request Literature | Tocris Bioscience</title> <meta name="description" content="Tocris Bioscience produces a range of literature including product guides, scientific reviews &amp; posters. We invite you to request your copy today." /> <meta name="robots" content="noindex" /> <meta http-equiv="content-language" content="en-us" /> <link href="https://www.tocris.com/literature/literature-request/234525" rel="alternate" hreflang="x-default" /> <link href="https://www.tocris.com/literature/literature-request/234525" rel="alternate" hreflang="en" /> <link href="https://www.tocris.com/cn/literature/literature-request/234525" rel="alternate" hreflang="zh-cn" /> <meta name="baidu-site-verification" content="bMqlqGgPRi" /> <script id="json-ld" type="application/ld+json">[{"@context":"http://schema.org","@type":"WebPage","breadcrumb":{"@context":"http://schema.org","@type":"BreadcrumbList","itemListElement":[{"@context":"http://schema.org","@type":"ListItem","position":1,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.tocris.com/","name":"Home"}},{"@context":"http://schema.org","@type":"ListItem","position":2,"item":{"@context":"http://schema.org","@type":"Thing","@id":"https://www.tocris.com/literature","name":"Literature"}}]},"potentialaction":{"query":""}}]</script> <meta name="generator" content="Drupal 7 (https://www.drupal.org)" /> <link rel="shortlink" href="https://www.tocris.com/literature/literature-request/234525" /> <meta property="og:site_name" content="Tocris Bioscience" /> <meta property="og:type" content="article" /> <meta property="og:url" content="https://www.tocris.com/literature/literature-request/234525" /> <meta property="og:title" content="Request Literature" /> <meta property="og:image" content="https://resources.tocris.com/images/Social/2019TocrisLogoV.png" /> <link type="text/css" rel="stylesheet" href="https://www.tocris.com/sites/tocris.com/files/css/css_gbdeDwx2KR-3alrXD8Yvh_KvMl7rp9fb8nDnlYMc6JE.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.tocris.com/sites/tocris.com/files/css/css_ZFPWfTE8WRD_QuXXZ4pXmOP_txiYrSgb2U-wb-M98WU.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.tocris.com/sites/tocris.com/files/css/css_E9wOyVBBPLIeq4Al4boCEX0keoOVPHA0RDiCFZgx0Co.css" media="screen" /> <link type="text/css" rel="stylesheet" href="https://www.tocris.com/sites/tocris.com/files/css/css_eTEze5CVY-FBlnpOcPnT07LL13ldh28hUqX2hi45QiA.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.tocris.com/sites/tocris.com/files/css/css_2cIL7DRD_8IFE8AjsWE4qk8TKbLKR-J8obZIgW5UNdM.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://resources.tocris.com/bootstrap/bootstrap.min.css" media="all" /> <link type="text/css" rel="stylesheet" href="https://www.tocris.com/sites/tocris.com/files/css/css_oPXAh5zWUMbTd4lSRWCKMwfGfcGDoiwO8Swk6V4T2Qk.css" media="all" />   <script src="https://www.tocris.com/sites/tocris.com/files/js/js_r1OC5xdRG2cR3ewVbCVMpsuSArUnbrxRo0KqbAuY3rM.js"></script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js_sAnmYfqPupk2sidWg7joDvbNo107Utmqwl2alpBSG2s.js"></script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js_EuQyiwmuajX0UwOaqfOyM-NkFfY6hWEShU6EMG33reM.js"></script> <script src="https://resources.tocris.com/bootstrap/bootstrap.min.js"></script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js_Mxv9UFtbr0o94bNhP1D7EsLV0jAny0TnE-BPcXcny98.js"></script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js_4OVqPzKQLFW0Y6Lp7eLuBpTer9591EEwwP6Cz8vxFY4.js"></script> <script>var dataLayer = dataLayer || []; dataLayer.push({"email": ""});</script> <script>var dataLayer = dataLayer || [] dataLayer.push({"event":"userRole","userRole":"anonymous user"});</script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js_qSLK6sec_HD6cn6dBmvEEuS61rTnxTCFXPJd_HS0nvI.js"></script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js__JuFmti1OZYyBBidIUJvoDOZg81ze1_8XkKpzZ5SPsY.js"></script> <script>jQuery.extend(Drupal.settings, {"basePath":"\/","pathPrefix":"","setHasJsCookie":0,"ajaxPageState":{"theme":"Tocris_2017","theme_token":"tViZ744nv6ndwEV8IV2yh43ryrdTrmvLRKQR_m8XscA","jquery_version":"2.2","js":{"0":1,"sites\/all\/modules\/contrib\/clientside_validation\/clientside_validation_html5\/clientside_validation_html5.js":1,"sites\/all\/themes\/bootstrap\/js\/bootstrap.js":1,"public:\/\/google_tag\/language\/google_tag.en.script.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/jquery\/2.2\/jquery.min.js":1,"misc\/jquery-extend-3.4.0.js":1,"misc\/jquery-html-prefilter-3.5.0-backport.js":1,"misc\/jquery.once.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.core.min.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.widget.min.js":1,"misc\/drupal.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_cookie.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jQuery_cycle2.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/ekko-lightbox.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/et-ekko-lightbox.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_hoverintent.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jquery_lazyload.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.position.min.js":1,"misc\/ui\/jquery.ui.position-1.13.0-backport.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.menu.min.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.autocomplete.min.js":1,"sites\/all\/modules\/enterprise-tech\/et_searchbar\/js\/searchbar_autocomplete.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/external\/jquery.cookie.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/jquery.form\/4\/jquery.form.min.js":1,"sites\/all\/modules\/enterprise-tech\/et_quickorder_responsive\/js\/et_quickorder_responsive.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.effect.min.js":1,"sites\/tocris.com\/modules\/jquery_update\/replace\/ui\/ui\/minified\/jquery.ui.effect-highlight.min.js":1,"misc\/form-single-submit.js":1,"misc\/ajax.js":1,"sites\/tocris.com\/modules\/jquery_update\/js\/jquery_update.js":1,"https:\/\/resources.tocris.com\/bootstrap\/bootstrap.min.js":1,"sites\/all\/modules\/contrib\/fields\/entityreference\/js\/entityreference.js":1,"sites\/all\/modules\/enterprise-tech\/et_internationalization\/js\/et_internationalization.js":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/js\/jQuery_et.js":1,"sites\/all\/modules\/enterprise-tech\/et_top_scroll\/js\/top_scroll.js":1,"sites\/all\/modules\/contrib\/globallink\/js\/globallink_active_submissions.js":1,"sites\/all\/modules\/contrib\/globallink\/js\/globallink_send_translations.js":1,"sites\/all\/modules\/contrib\/globallink\/js\/globallink_field_configuration.js":1,"sites\/all\/modules\/contrib\/globallink\/globallink_entity\/js\/globallink_entity_active_submissions.js":1,"sites\/all\/modules\/contrib\/globallink\/globallink_entity\/js\/globallink_entity_send.js":1,"sites\/all\/modules\/contrib\/globallink\/globallink_menu\/js\/globallink_menu_active_submissions.js":1,"sites\/all\/modules\/contrib\/globallink\/globallink_taxonomy\/js\/globallink_taxonomy_active_submissions.js":1,"sites\/all\/modules\/contrib\/marketo_ma\/js\/marketo_ma.js":1,"sites\/all\/modules\/enterprise-tech\/et_cookie_policy\/js\/et_cookie_policy.js":1,"sites\/all\/modules\/enterprise-tech\/et_search\/json_viewer\/js\/jsonviewer.js":1,"sites\/tocris.com\/modules\/et_tocris_literature\/js\/et_tocris_literature.js":1,"sites\/tocris.com\/modules\/et_tocris_webforms\/js\/literature_request.js":1,"sites\/all\/modules\/enterprise-tech\/et_searchbar\/js\/et_searchbar.js":1,"sites\/all\/themes\/bootstrap\/js\/misc\/_progress.js":1,"sites\/all\/modules\/et_commerce\/et_atc_blocks\/js\/et_atc_blocks.js":1,"sites\/all\/modules\/et_commerce\/et_atc_blocks\/js\/et_atc_cart_summary.js":1,"sites\/all\/modules\/enterprise-tech\/et_combined_seo\/js\/et_combined_seo.js":1,"1":1,"2":1,"sites\/tocris.com\/themes\/Tocris_2017\/js\/tocris.js":1,"sites\/tocris.com\/themes\/Tocris_2017\/js\/et_mobile_theme.js":1,"sites\/tocris.com\/themes\/Tocris_2017\/js\/tocris_menu.js":1,"sites\/tocris.com\/themes\/Tocris_2017\/js\/distributors.js":1,"sites\/all\/themes\/bootstrap\/js\/misc\/ajax.js":1},"css":{"modules\/system\/system.base.css":1,"sites\/all\/modules\/enterprise-tech\/et_javafunctions\/css\/ekko-lightbox.css":1,"misc\/ui\/jquery.ui.core.css":1,"misc\/ui\/jquery.ui.theme.css":1,"misc\/ui\/jquery.ui.menu.css":1,"misc\/ui\/jquery.ui.autocomplete.css":1,"sites\/all\/modules\/enterprise-tech\/et_quickorder_responsive\/css\/et_quickorder_responsive.css":1,"sites\/all\/modules\/enterprise-tech\/et_internationalization\/css\/et_internationalization.css":1,"sites\/all\/modules\/enterprise-tech\/et_product_page_promo\/css\/et_product_page_promo.css":1,"sites\/all\/modules\/enterprise-tech\/et_top_scroll\/css\/top_scroll.css":1,"modules\/field\/theme\/field.css":1,"sites\/all\/modules\/contrib\/globallink\/css\/globallink_active_submissions.css":1,"modules\/node\/node.css":1,"sites\/all\/modules\/contrib\/views\/css\/views.css":1,"sites\/all\/modules\/contrib\/userInterface\/ckeditor\/css\/ckeditor.css":1,"sites\/all\/modules\/contrib\/ctools\/css\/ctools.css":1,"sites\/tocris.com\/modules\/et_tocris_webforms\/css\/et_tocris_webforms.css":1,"https:\/\/resources.rndsystems.com\/bootstrap\/drupal-bootstrap.min.css":1,"https:\/\/resources.tocris.com\/bootstrap\/bootstrap.min.css":1,"sites\/tocris.com\/themes\/Tocris_2017\/css\/style.css":1}},"country_name":"United States","et_internationalization":{"social":"Default","distphone":""},"et_searchbar":{"min_chars":3},"urlIsAjaxTrusted":{"\/literature\/literature-request\/234525":true},"et_quickorder_responsive":{"enabled":true,"show_cart":"1","display_price":"0","isDistributor":false},"bootstrap":{"anchorsFix":"0","anchorsSmoothScrolling":"0","formHasError":1,"popoverEnabled":0,"popoverOptions":{"animation":1,"html":0,"placement":"right","selector":"","trigger":"click","triggerAutoclose":1,"title":"","content":"","delay":0,"container":"body"},"tooltipEnabled":0,"tooltipOptions":{"animation":1,"html":0,"placement":"auto left","selector":"","trigger":"hover focus","delay":0,"container":"body"}}});</script> <link rel="apple-touch-icon" sizes="180x180" href="/sites/tocris.com/themes/Tocris_2017/images/favicons/apple-touch-icon.png"> <link rel="icon" type="image/png" href="/sites/tocris.com/themes/Tocris_2017/images/favicons/favicon-32x32.png" sizes="32x32"> <link rel="icon" type="image/png" href="/sites/tocris.com/themes/Tocris_2017/images/favicons/favicon-16x16.png" sizes="16x16"> <link rel="manifest" href="/sites/tocris.com/themes/Tocris_2017/images/favicons/manifest.json"> <link rel="mask-icon" href="/sites/tocris.com/themes/Tocris_2017/images/favicons/safari-pinned-tab.svg" color="#5bbad5"> <link rel="shortcut icon" href="/sites/tocris.com/themes/Tocris_2017/images/favicons/favicon.ico"> <meta name="apple-mobile-web-app-title" content="Tocris Bioscience"> <meta name="application-name" content="Tocris Bioscience"> <meta name="msapplication-config" content="/sites/tocris.com/themes/Tocris_2017/images/favicons/browserconfig.xml"> <meta name="theme-color" content="#ffffff"> </head> <body class="html not-front not-logged-in no-sidebars page-literature page-literature-literature-request page-literature-literature-request- page-literature-literature-request-234525 i18n-en" base-theme="Tocris_2017">  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-52P87LJ" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>  <div id="skip-link"> <a href="#main-content" class="element-invisible element-focusable">Skip to main content</a> </div> <div class="region region-page-top"> <noscript aria-hidden="true"><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-52P87LJ" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> </div> <header id="header" role="banner">   <div id="bb_container"> <div id="brands_bar"> <div class="region region-brands-bar"> <section id="block-bt-brands-bar-bt-brands-bar" class="block block-bt-brands-bar clearfix"> <li class="bb_biotechne"><a href="https://www.bio-techne.com" rel="noopener noreferrer" target="_blank" aria-label="Bio-Techne"></a></li><li class="bb_rndsystems"><a href="https://www.rndsystems.com" rel="noopener noreferrer" target="_blank" aria-label="R&D Systems"></a></li><li class="bb_novusbio"><a href="https://www.novusbio.com" rel="noopener noreferrer" target="_blank" aria-label="Novus Biologicals"></a></li><li class="bb_tocris active"><a href="https://www.tocris.com" rel="noopener noreferrer" target="_self" aria-label="Tocris Bioscience"></a></li><li class="bb_proteinsimple"><a href="https://www.bio-techne.com/brands/proteinsimple" rel="noopener noreferrer" target="_blank" aria-label="ProteinSimple"></a></li><li class="bb_biospacific"><a href="https://www.biospacific.com" rel="noopener noreferrer" target="_blank" aria-label="BiosPacific"></a></li><li class="bb_cliniqa"><a href="https://www.cliniqa.com" rel="noopener noreferrer" target="_blank" aria-label="Cliniqa"></a></li><li class="bb_acd"><a href="https://acdbio.com/ " rel="noopener noreferrer" target="_blank" aria-label="ACD"></a></li><li class="bb_rndheme"><a href="https://www.rndheme.com" rel="noopener noreferrer" target="_blank" aria-label="R&D Heme"></a></li> </section> </div> </div> </div> <div id="hd_container"> <div id="logo_block"> <section id="block-logo-block-logo" class="block block-logo-block clearfix"> <a href="/" title="Tocris.com" class="active"></a> </section> </div> <div id="search_bar"> <div class="region region-search-bar"> <section id="block-et-searchbar-et-searchbar-bar" class="block block-et-searchbar clearfix"> <form name="et_searchbar" method="GET" action="/search" class="search_form"><div class="et_searchbar"> <input autocomplete="off" name="keywords" type="text" class="et_searchbar_wide et_searchbar_default" value="" placeholder="Search Cat. No., Product or Target" data-default="" /><input type="submit" value="" class="fp_mag_glass_wideSearch"></div></form> </section> </div> </div> <div id="cart_menu_mobile" class="atc_cart_summary_icon"></div> <div id="account_menu_mobile"></div> <div id="account_menu"> <div class="region region-account-menu"> <section id="block-et-internationalization-country-dropdown" class="block block-et-internationalization clearfix"> <div id="internationalization_country_select"> <div class="internationalization_drop"></div> </div> </section> <section id="block-et-internationalization-sign-in" class="block block-et-internationalization clearfix"> <div id="sign_in"><a href="/user/login" rel="nofollow"><noscript>Account</noscript></a></div> </section> <section id="block-et-atc-blocks-et-atc-cart-summary" class="block block-et-atc-blocks clearfix"> <ul class="menu nav"> <li class="first last leaf active"><a href="/cart" class="active atc_cart_summary_icon"><span class="atc_blocks_items_in_cart">0</span> Items</a></li> </ul> </section> <section id="block-et-cookie-policy-cookie-policy" class="block block-et-cookie-policy clearfix"> <div></div> </section> </div> </div> </div> <div id="mm_container"> <div id="main_menu_mobile"></div> <nav id="main_menu"> <div class="region region-main-menu"> <section id="block-system-main-menu" class="block block-system block-menu clearfix"> <ul class="menu nav"><li class="first expanded dropdown"><a href="/products" id="main-menu-577" data-target="#">Products <span class="caret"></span></a><div class="menu_toggle"></div><ul class="dropdown-menu"><li class="first expanded dropdown"><a href="/pharmacology" id="main-menu-3526" data-target="#">Pharmacology <span class="caret"></span></a><div class="menu_toggle"></div><ul class="third-level-menu"><li class="first leaf"><a href="/pharmacology/7-tm-receptors" id="main-menu-3966">GPCRs / 7-TM Receptors</a></li> <li class="leaf"><a href="/pharmacology/enzyme-linked-receptors" id="main-menu-4221">Enzyme-Linked Receptors</a></li> <li class="leaf"><a href="/pharmacology/enzymes" id="main-menu-4231">Enzymes</a></li> <li class="leaf"><a href="/pharmacology/ion-channels" id="main-menu-4211">Ion Channels</a></li> <li class="leaf"><a href="/pharmacology/nuclear-receptors" id="main-menu-4216">Nuclear Receptors</a></li> <li class="leaf"><a href="/pharmacology/transporters" id="main-menu-4226">Transporters</a></li> <li class="leaf"><a href="/pharmacology/other-pharmacology" id="main-menu-4236">Other Pharmacology</a></li> <li class="last leaf"><a href="/pharmacology/all-targets/0-9" id="main-menu-6456">All Targets</a></li> </ul></li> <li class="expanded dropdown"><a href="/cell-biology" id="main-menu-3971" data-target="#">Cell Biology <span class="caret"></span></a><div class="menu_toggle"></div><ul class="third-level-menu"><li class="first leaf"><a href="/cell-biology/angiogenesis" id="main-menu-4241">Angiogenesis</a></li> <li class="leaf"><a href="/cell-biology/cell-cycle" id="main-menu-4246">Cell Cycle</a></li> <li class="leaf"><a href="/cell-biology/cell-metabolism" id="main-menu-4251">Cell Metabolism</a></li> <li class="leaf"><a href="/cell-biology/cytoskeleton-and-motor-proteins" id="main-menu-4256">Cytoskeleton & Motor Proteins</a></li> <li class="leaf"><a href="/cell-biology/extracellular-matrix-and-adhesion-molecules" id="main-menu-4261">ECM & Adhesion Molecules</a></li> <li class="leaf"><a href="/cell-biology/epigenetics" id="main-menu-4266">Epigenetics</a></li> <li class="leaf"><a href="/cell-biology/regulated-cell-death" id="main-menu-3981">Regulated Cell Death</a></li> <li class="leaf"><a href="/cell-biology/signal-transduction" id="main-menu-4271">Signal Transduction</a></li> <li class="last leaf"><a href="/cell-biology/stem-cells" id="main-menu-4276">Stem Cells</a></li> </ul></li> <li class="expanded dropdown"><a href="/product-type" id="main-menu-3986" data-target="#">Product Type <span class="caret"></span></a><div class="menu_toggle"></div><ul class="third-level-menu"><li class="first leaf"><a href="/product-type/all-products" id="main-menu-3991">All Products</a></li> <li class="leaf"><a href="/product-type/small-molecules" id="main-menu-4281">Small Molecules</a></li> <li class="leaf"><a href="/product-type/peptides" id="main-menu-4286">Peptides</a></li> <li class="leaf"><a href="/product-type/chemogenetics" id="main-menu-4311">Chemogenetics </a></li> <li class="leaf"><a href="/product-type/controlled-substances" id="main-menu-4291">Controlled Substances</a></li> <li class="leaf"><a href="/product-type/tocriscreen-compound-libraries" id="main-menu-4366">Compound Libraries</a></li> <li class="leaf"><a href="/product-type/fluorescence-imaging" id="main-menu-4321">Fluorescence Imaging</a></li> <li class="leaf"><a href="/product-type/gmp-ancillary-material-grade-small-molecules" id="main-menu-14146">GMP & Ancillary Material Grade Small Molecules</a></li> <li class="leaf"><a href="/product-type/optopharmacology" id="main-menu-12761">Optopharmacology</a></li> <li class="leaf"><a href="/product-type/targeted-protein-degradation" class="menu-item-updated" id="main-menu-13196">PROTACs & Targeted Protein Degradation</a></li> <li class="leaf"><a href="/product-type/reagents" id="main-menu-4331">Reagents</a></li> <li class="leaf"><a href="/product-type/stapled-peptides" id="main-menu-15251">Stapled Peptides</a></li> <li class="last leaf"><a href="/product-type/toxins" id="main-menu-4296">Toxins</a></li> </ul></li> <li class="expanded dropdown"><a href="/research-area" id="main-menu-7406" data-target="#">Research Area <span class="caret"></span></a><div class="menu_toggle"></div><ul class="third-level-menu"><li class="first leaf"><a href="/research-area/cancer-research" class="menu-item-updated" id="main-menu-7411">Cancer</a></li> <li class="leaf"><a href="/research-area/cardiovascular-system-research" id="main-menu-7416">Cardiovascular System</a></li> <li class="leaf"><a href="/research-area/cell-and-gene-therapy" id="main-menu-15266">Cell and Gene Therapy</a></li> <li class="leaf"><a href="/research-area/covid-19-research" id="main-menu-15306">COVID-19 Research</a></li> <li class="leaf"><a href="/research-area/endocrinology-research" id="main-menu-7421">Endocrinology</a></li> <li class="leaf"><a href="/research-area/immunology-research" id="main-menu-7426">Immunology</a></li> <li class="leaf"><a href="/research-area/infectious-disease" id="main-menu-15296">Infectious Disease</a></li> <li class="leaf"><a href="/research-area/neuroscience-research" id="main-menu-7431">Neuroscience</a></li> <li class="leaf"><a href="/research-area/pain-and-inflammation-research" id="main-menu-7436">Pain & Inflammation</a></li> <li class="last leaf"><a href="/research-area/respiratory-system-research" id="main-menu-7441">Respiratory System</a></li> </ul></li> <li class="last leaf"><a href="/product-type/new-products" id="main-menu-3996">New Products</a></li> </ul></li> <li class="expanded dropdown"><a href="/support" id="main-menu-578" data-target="#">Support <span class="caret"></span></a><div class="menu_toggle"></div><ul class="dropdown-menu short"><li class="first leaf"><a href="/support/customer-support" id="main-menu-13886">Customer Support</a></li> <li class="leaf"><a href="/support/technical-support" id="main-menu-13881">Technical Support</a></li> <li class="leaf"><a href="/support/contact-us" id="main-menu-7466">Contact Us</a></li> <li class="leaf"><a href="/distributors" id="main-menu-7471">Distributors</a></li> <li class="leaf"><a href="/support/leave-feedback" rel="nofollow" id="main-menu-8151">Leave Feedback</a></li> <li class="leaf"><a href="/scholarship" id="main-menu-13181">Scholarship Program</a></li> <li class="leaf"><a href="/reviews" rel="nofollow" id="main-menu-9596">Submit a Review</a></li> <li class="leaf"><a href="/support/promotions" id="main-menu-13351">Promotions</a></li> <li class="leaf"><a href="/support/bulk-quantities-form" rel="nofollow" id="main-menu-9466">Bulk Quantity Discounts</a></li> <li class="leaf"><a href="/support/gmp-compound-inquiry" rel="nofollow" id="main-menu-13201">GMP Compound Register Interest</a></li> <li class="last leaf"><a href="/support/screening-inquiry" id="main-menu-15291">Screening Inquiry</a></li> </ul></li> <li class="expanded dropdown"><a href="/resources" id="main-menu-579" data-target="#">Resources <span class="caret"></span></a><div class="menu_toggle"></div><ul class="dropdown-menu short"><li class="first leaf"><a href="/signaling-pathways" title="Signaling Pathways" id="main-menu-7341">Signaling Pathways</a></li> <li class="leaf"><a href="/resources/peptide-nomenclature-guide" id="main-menu-13811">Peptide Nomenclature Guide</a></li> <li class="leaf"><a href="/resources/pharmacological-glossary" id="main-menu-13816">Pharmacological Glossary</a></li> <li class="leaf"><a href="/resources/useful-abbreviations" id="main-menu-13821">Useful Abbreviations</a></li> <li class="leaf"><a href="/resources/dilution-calculator" id="main-menu-13826">Dilution Calculator</a></li> <li class="leaf"><a href="/resources/molarity-calculator" id="main-menu-13831">Molarity Calculator</a></li> <li class="leaf"><a href="/resources/reconstitution-calculator" id="main-menu-13836">Reconstitution Calculator</a></li> <li class="leaf"><a href="/resources/protocols" id="main-menu-13186">Protocols</a></li> <li class="leaf"><a href="/resources/tocris-blog" id="main-menu-12776">Tocris Blog</a></li> <li class="leaf"><a href="/resources/webinars-and-videos" id="main-menu-13136">Webinars & Videos</a></li> <li class="last leaf"><a href="/resources/spectral-viewer" id="main-menu-14186">Spectra Viewer</a></li> </ul></li> <li class="expanded dropdown"><a href="/services" id="main-menu-13171" data-target="#">Services <span class="caret"></span></a><div class="menu_toggle"></div><ul class="dropdown-menu short"><li class="first leaf"><a href="/services/custom-synthesis" id="main-menu-13781">Custom Synthesis</a></li> <li class="leaf"><a href="/services/chemical-analysis" id="main-menu-13786">Chemical Analysis</a></li> <li class="leaf"><a href="/services/chemical-sourcing" id="main-menu-13791">Chemical Sourcing</a></li> <li class="leaf"><a href="/services/facilities" id="main-menu-13796">Facilities</a></li> <li class="leaf"><a href="/services/expertise" id="main-menu-13801">Expertise</a></li> <li class="leaf"><a href="/services/why-choose-tocris" id="main-menu-13806">Why Choose Tocris?</a></li> <li class="leaf"><a href="/services/request-quote" id="main-menu-15156">Request Quote</a></li> <li class="leaf"><a href="/about-tocris/tocriscreen-pro-custom-compound-library-service" id="main-menu-16551">Custom Compound Library Service</a></li> <li class="leaf"><a href="/services/custom-degrader-services" id="main-menu-15101">Custom Degrader Services</a></li> <li class="last leaf"><a href="/protac-panel-builder" id="main-menu-15406">PROTAC庐 Panel Builder</a></li> </ul></li> <li class="expanded dropdown"><a href="/literature" id="main-menu-7451" data-target="#">Literature <span class="caret"></span></a><div class="menu_toggle"></div><ul class="dropdown-menu short"><li class="first leaf"><a href="/literature/life-science-posters" id="main-menu-6431">Life Science Posters</a></li> <li class="leaf"><a href="/literature/scientific-posters" id="main-menu-15146">Scientific Meeting Posters</a></li> <li class="leaf"><a href="/literature/product-guides" id="main-menu-6441">Product Guides & Listings</a></li> <li class="leaf"><a href="/literature/research-bulletins" id="main-menu-6446">Research Bulletins</a></li> <li class="leaf"><a href="/literature/scientific-reviews" id="main-menu-6436">Scientific Reviews</a></li> <li class="leaf"><a href="/literature/signup" rel="nofollow" id="main-menu-9306">Sign Up for E-Alerts</a></li> <li class="last leaf"><a href="/literature/literature-request" rel="nofollow" id="main-menu-9311">Request Literature</a></li> </ul></li> <li class="expanded dropdown"><a href="/about-tocris" id="main-menu-14011" data-target="#">About Tocris <span class="caret"></span></a><div class="menu_toggle"></div><ul class="dropdown-menu short"><li class="first leaf"><a href="/about-tocris/your-supplier-of-choice" id="main-menu-14131">Your Supplier of Choice</a></li> <li class="leaf"><a href="/about-tocris/tocris-history" id="main-menu-13856">Tocris History</a></li> <li class="leaf"><a href="/about-tocris/tocris-in-the-news" id="main-menu-13851">Tocris in the News</a></li> <li class="leaf"><a href="/about-tocris/tocris-events" id="main-menu-13871">Events & Conferences</a></li> <li class="leaf"><a href="/about-tocris/licensing" id="main-menu-13866">Licensing</a></li> <li class="leaf"><a href="/about-tocris/our-ethos" id="main-menu-13861">Our Ethos</a></li> <li class="leaf"><a href="/about-tocris/environment" id="main-menu-13876">Environment</a></li> <li class="last leaf"><a href="/about-tocris/careers-at-tocris" id="main-menu-13846">Careers</a></li> </ul></li> <li class="last leaf"><a href="/support/contact-us" id="main-menu-7501">Contact Us</a></li> </ul> </section> </div> </nav> </div> </header> <div class="breadcrumbs_wrapper"> <div class="breadcrumbs_container"> <div class="breadcrumb"><a href="/">Home</a> <span class="breadcrumb_separator">/</span> <a href="/literature">Literature</a> <span class="breadcrumb_separator">/</span> Request Literature</div> </div> </div> <div class="main-container container"> <div class="row"> <section> <a id="main-content"></a> <div class="col-xs-12 col-sm-12 col-md-12"> <h1>Request Literature</h1> <form action="/literature/literature-request/234525" method="post" id="literature-request-form" accept-charset="UTF-8"><div><div id="edit-subheading" class="form-item form-type-item form-group"><h2>The literature you requested has been pre-selected.</h2><span class="glyphicon glyphicon-plus-sign"></span><p>The literature you requested has been pre-selected. <b>If you would like to add more literature items to your request, please select them in the sections below.</b> When you are happy with your selections, please select the continue button at the bottom of the page*.</p> <p class="small">*Please note that Tocris will only send literature to established scientific business / institute addresses.</p> <div id="selected_lit" class="lit" ><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234525" data-is_selected="1"><img src="https://resources.tocris.com/images/literature/reviews/regular/234525.jpg?v=2" class="img_prod_guides" alt="5-HT Receptors" title="View further information about 5-HT Receptors"><p class="lit_title">5-HT Receptors</p><div class="234525 request_lit_not"><div class="request"><span class="request_text">Selected</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234525" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div></div><div style="clear:both"></div> </div><button type="submit" id="edit-next-top" name="op" value="Continue" class="btn btn-default form-submit">Continue</button> <div id="edit-literature-display" class="form-item form-type-item form-group"><div class="lit"></span><div class="lit_group clearfix" id="103" ><hr/><h3 class="subhead">Product Guides & Listings</h3><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="783287" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/783287.jpg" class="img_prod_guides" alt="Alzheimer's Disease" title="View further information about Alzheimer's Disease"><p class="lit_title">Alzheimer's Disease</p><div class="783287 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p783287" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="837762" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/837762.jpg" class="img_prod_guides" alt="Angiogenesis in Cancer" title="View further information about Angiogenesis in Cancer"><p class="lit_title">Angiogenesis in Cancer</p><div class="837762 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p837762" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="815385" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/815385.jpg?v=2" class="img_prod_guides" alt="Cancer Metabolism" title="View further information about Cancer Metabolism"><p class="lit_title">Cancer Metabolism</p><div class="815385 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p815385" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="727930" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/727930.jpg?v=3" class="img_prod_guides" alt="Cell Cycle and DNA Damage" title="View further information about Cell Cycle and DNA Damage"><p class="lit_title">Cell Cycle and DNA Damage</p><div class="727930 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p727930" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="814154" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/814154.jpg?v=2" class="img_prod_guides" alt="Epigenetics in Cancer" title="View further information about Epigenetics in Cancer"><p class="lit_title">Epigenetics in Cancer</p><div class="814154 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p814154" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="707399" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/707399.jpg?v=3" class="img_prod_guides" alt="Fluorescent Dyes and Probes" title="View further information about Fluorescent Dyes and Probes"><p class="lit_title">Fluorescent Dyes and Probes</p><div class="707399 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p707399" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="746077" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/746077.jpg?v=2" class="img_prod_guides" alt="Huntington's Disease" title="View further information about Huntington's Disease"><p class="lit_title">Huntington's Disease</p><div class="746077 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p746077" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="775591" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/775591.jpg" class="img_prod_guides" alt="MitoBrilliant" title="View further information about MitoBrilliant"><p class="lit_title">MitoBrilliant</p><div class="775591 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p775591" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="828660" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/828660.jpg?v=1" class="img_prod_guides" alt="Neural Stem Cell Workflow Solutions" title="View further information about Neural Stem Cell Workflow Solutions"><p class="lit_title">Neural Stem Cell Workflow Solutions</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p828660" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="759724" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/759724.jpg" class="img_prod_guides" alt="Parkinson's Disease" title="View further information about Parkinson's Disease"><p class="lit_title">Parkinson's Disease</p><div class="759724 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p759724" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="683696" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/683696.jpg?v=4" class="img_prod_guides" alt="Stem Cell" title="View further information about Stem Cell"><p class="lit_title">Stem Cell</p><div class="683696 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p683696" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="845381" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/845381.jpg" class="img_prod_guides" alt="The Organoid Handbook" title="View further information about The Organoid Handbook"><p class="lit_title">The Organoid Handbook</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p845381" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="697383" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/697383.jpg?v=2" class="img_prod_guides" alt="Tocriscreen Compound Libraries" title="View further information about Tocriscreen Compound Libraries"><p class="lit_title">Tocriscreen Compound Libraries</p><div class="697383 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p697383" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="634432" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/product-guides/regular/634432.jpg?v=8" class="img_prod_guides" alt="TPD and Induced Proximity" title="View further information about TPD and Induced Proximity"><p class="lit_title">TPD and Induced Proximity</p><div class="634432 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p634432" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div></div></span><div class="lit_group clearfix" id="126" ><hr/><h3 class="subhead">Scientific Reviews</h3><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234525" data-is_selected="1"><img src="https://resources.tocris.com/images/literature/reviews/regular/234525.jpg?v=2" class="img_prod_guides" alt="5-HT Receptors" title="View further information about 5-HT Receptors"><p class="lit_title">5-HT Receptors</p><div class="234525 request_lit_not"><div class="request"><span class="request_text">Selected</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234525" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="359078" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/359078.jpg?v=2" class="img_prod_guides" alt="Autophagy" title="View further information about Autophagy"><p class="lit_title">Autophagy</p><div class="359078 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p359078" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234511" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/234511.jpg?v=2" class="img_prod_guides" alt="Cannabinoid Receptor Ligands" title="View further information about Cannabinoid Receptor Ligands"><p class="lit_title">Cannabinoid Receptor Ligands</p><div class="234511 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234511" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234512" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/234512.jpg?v=1" class="img_prod_guides" alt="Dopamine Receptors" title="View further information about Dopamine Receptors"><p class="lit_title">Dopamine Receptors</p><div class="234512 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234512" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="417572" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/417572.jpg?v=2" class="img_prod_guides" alt="Epigenetics" title="View further information about Epigenetics"><p class="lit_title">Epigenetics</p><div class="417572 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p417572" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234514" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/234514.jpg?v=2" class="img_prod_guides" alt="GABA Receptors" title="View further information about GABA Receptors"><p class="lit_title">GABA Receptors</p><div class="234514 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234514" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234515" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/234515.jpg?v=2" class="img_prod_guides" alt="Histamine Receptors" title="View further information about Histamine Receptors"><p class="lit_title">Histamine Receptors</p><div class="234515 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234515" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="522385" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/522385.jpg?v=1" class="img_prod_guides" alt="MAPK Signaling" title="View further information about MAPK Signaling"><p class="lit_title">MAPK Signaling</p><div class="522385 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p522385" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234517" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/234517.jpg?v=2" class="img_prod_guides" alt="Metabotropic Glutamate Receptors" title="View further information about Metabotropic Glutamate Receptors"><p class="lit_title">Metabotropic Glutamate Receptors</p><div class="234517 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234517" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234518" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/234518.jpg?v=2" class="img_prod_guides" alt="Nicotinic ACh Receptors" title="View further information about Nicotinic ACh Receptors"><p class="lit_title">Nicotinic ACh Receptors</p><div class="234518 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234518" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="268401" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/268401.jpg?v=3" class="img_prod_guides" alt="P2X and P2Y Receptors" title="View further information about P2X and P2Y Receptors"><p class="lit_title">P2X and P2Y Receptors</p><div class="268401 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p268401" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="234521" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/234521.jpg?v=1" class="img_prod_guides" alt="Peptides Involved in Appetite Modulation" title="View further information about Peptides Involved in Appetite Modulation"><p class="lit_title">Peptides Involved in Appetite Modulation</p><div class="234521 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p234521" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="537174" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/537174.jpg?v=4" class="img_prod_guides" alt="RAS Oncoproteins" title="View further information about RAS Oncoproteins"><p class="lit_title">RAS Oncoproteins</p><div class="537174 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p537174" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="298321" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/298321.jpg?v=2" class="img_prod_guides" alt="Retinoid Receptors" title="View further information about Retinoid Receptors"><p class="lit_title">Retinoid Receptors</p><div class="298321 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p298321" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="298320" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/reviews/regular/298320.jpg?v=2" class="img_prod_guides" alt="Stem Cells" title="View further information about Stem Cells"><p class="lit_title">Stem Cells</p><div class="298320 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><div class="ind_pdf request_pdf" data-itemid="p298320" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div></div></span><div class="lit_group clearfix" id="128" ><hr/><h3 class="subhead">Research Bulletins</h3><div class="ind_lit_wrapper ind_lit_wrapper_med" ><div class="ind_lit ind_lit_tall" data-itemid="594240" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/research-bulletins/regular/594240.jpg?v=1" class="img_prod_guides" alt="Chemogenetics" title="View further information about Chemogenetics"><p class="lit_title">Chemogenetics</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p594240" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div></div></span><div class="lit_group clearfix" id="125" ><hr/><h3 class="subhead">Life Science Posters</h3><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="494370" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/494370.jpg" class="img_prod_guides" alt="Addiction" title="View further information about Addiction"><p class="lit_title">Addiction</p><div class="494370 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/addiction-poster-2016.pdf" download="https://resources.tocris.com/pdfs/literature/posters/addiction-poster-2016.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/addiction-poster-2016.pdf" data-pdfitem="494370" data-title="Addiction" target="_blank"><div class="pdf_wording" id="pdf_494370"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="636206" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/636206.jpg" class="img_prod_guides" alt="Allosteric GPCR Pharmacology" title="View further information about Allosteric GPCR Pharmacology"><p class="lit_title">Allosteric GPCR Pharmacology</p><div class="636206 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/allosteric-gpcr-pharmacology-poster-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/allosteric-gpcr-pharmacology-poster-2019.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/allosteric-gpcr-pharmacology-poster-2019.pdf" data-pdfitem="636206" data-title="Allosteric GPCR Pharmacology" target="_blank"><div class="pdf_wording" id="pdf_636206"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="244891" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/244891.jpg?v=1" class="img_prod_guides" alt="Alzheimer's Disease" title="View further information about Alzheimer's Disease"><p class="lit_title">Alzheimer's Disease</p><div class="244891 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/alzheimers-poster-2023.pdf" download="https://resources.tocris.com/pdfs/literature/posters/alzheimers-poster-2023.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/alzheimers-poster-2023.pdf" data-pdfitem="244891" data-title="Alzheimer's Disease" target="_blank"><div class="pdf_wording" id="pdf_244891"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="525564" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/525564.jpg?v=2" class="img_prod_guides" alt="Angiogenesis in Cancer" title="View further information about Angiogenesis in Cancer"><p class="lit_title">Angiogenesis in Cancer</p><div class="525564 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/angiogenesis-cancer-2023-poster.pdf" download="https://resources.tocris.com/pdfs/literature/posters/angiogenesis-cancer-2023-poster.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/angiogenesis-cancer-2023-poster.pdf" data-pdfitem="525564" data-title="Angiogenesis in Cancer" target="_blank"><div class="pdf_wording" id="pdf_525564"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="368180" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/368180.jpg" class="img_prod_guides" alt="Autophagy" title="View further information about Autophagy"><p class="lit_title">Autophagy</p><div class="368180 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/autophagy-poster-2014.pdf" download="https://resources.tocris.com/pdfs/literature/posters/autophagy-poster-2014.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/autophagy-poster-2014.pdf" data-pdfitem="368180" data-title="Autophagy" target="_blank"><div class="pdf_wording" id="pdf_368180"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="482944" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/482944.jpg?v=1" class="img_prod_guides" alt="Cancer Metabolism" title="View further information about Cancer Metabolism"><p class="lit_title">Cancer Metabolism</p><div class="482944 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/cancer-metabolism-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/cancer-metabolism-poster-2022.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/cancer-metabolism-poster-2022.pdf" data-pdfitem="482944" data-title="Cancer Metabolism" target="_blank"><div class="pdf_wording" id="pdf_482944"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="508457" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/508457.jpg?v=2" class="img_prod_guides" alt="Cell Cycle & DNA Damage Repair" title="View further information about Cell Cycle & DNA Damage Repair"><p class="lit_title">Cell Cycle & DNA Damage Repair</p><div class="508457 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/cell-cycle-dna-poster-2023.pdf" download="https://resources.tocris.com/pdfs/literature/posters/cell-cycle-dna-poster-2023.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/cell-cycle-dna-poster-2023.pdf" data-pdfitem="508457" data-title="Cell Cycle & DNA Damage Repair" target="_blank"><div class="pdf_wording" id="pdf_508457"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="234528" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/234528.jpg" class="img_prod_guides" alt="Depression" title="View further information about Depression"><p class="lit_title">Depression</p><div class="234528 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/depression-poster-2015.pdf" download="https://resources.tocris.com/pdfs/literature/posters/depression-poster-2015.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/depression-poster-2015.pdf" data-pdfitem="234528" data-title="Depression" target="_blank"><div class="pdf_wording" id="pdf_234528"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="482945" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/482945.jpg?v=2" class="img_prod_guides" alt="Epigenetics in Cancer" title="View further information about Epigenetics in Cancer"><p class="lit_title">Epigenetics in Cancer</p><div class="482945 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/epigenetics-cancer-poster-2023.pdf" download="https://resources.tocris.com/pdfs/literature/posters/epigenetics-cancer-poster-2023.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/epigenetics-cancer-poster-2023.pdf" data-pdfitem="482945" data-title="Epigenetics in Cancer" target="_blank"><div class="pdf_wording" id="pdf_482945"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="629782" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/629782.jpg" class="img_prod_guides" alt="GPCR Efficacy and Biased Agonism" title="View further information about GPCR Efficacy and Biased Agonism"><p class="lit_title">GPCR Efficacy and Biased Agonism</p><div class="629782 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/gpcr-efficacy-biased-agonism-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/gpcr-efficacy-biased-agonism-poster-v1-2019.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/gpcr-efficacy-biased-agonism-poster-v1-2019.pdf" data-pdfitem="629782" data-title="GPCR Efficacy and Biased Agonism" target="_blank"><div class="pdf_wording" id="pdf_629782"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="494492" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/494492.jpg" class="img_prod_guides" alt="Gut Hormones" title="View further information about Gut Hormones"><p class="lit_title">Gut Hormones</p><div class="494492 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/gut-hormone-poster-2017.pdf" download="https://resources.tocris.com/pdfs/literature/posters/gut-hormone-poster-2017.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/gut-hormone-poster-2017.pdf" data-pdfitem="494492" data-title="Gut Hormones" target="_blank"><div class="pdf_wording" id="pdf_494492"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="499073" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/499073.jpg?v=1" class="img_prod_guides" alt="Huntington's Disease" title="View further information about Huntington's Disease"><p class="lit_title">Huntington's Disease</p><div class="499073 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/huntingtons-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/huntingtons-poster-2022.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/huntingtons-poster-2022.pdf" data-pdfitem="499073" data-title="Huntington's Disease" target="_blank"><div class="pdf_wording" id="pdf_499073"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="494493" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/494493.jpg" class="img_prod_guides" alt="Multiple Sclerosis" title="View further information about Multiple Sclerosis"><p class="lit_title">Multiple Sclerosis</p><div class="494493 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/multiple-sclerosis-2016.pdf" download="https://resources.tocris.com/pdfs/literature/posters/multiple-sclerosis-2016.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/multiple-sclerosis-2016.pdf" data-pdfitem="494493" data-title="Multiple Sclerosis" target="_blank"><div class="pdf_wording" id="pdf_494493"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="234507" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/234507.jpg?v=2" class="img_prod_guides" alt="Parkinson's Disease" title="View further information about Parkinson's Disease"><p class="lit_title">Parkinson's Disease</p><div class="234507 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/parkinsons-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/parkinsons-poster-2022.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/parkinsons-poster-2022.pdf" data-pdfitem="234507" data-title="Parkinson's Disease" target="_blank"><div class="pdf_wording" id="pdf_234507"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="234501" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/234501.jpg" class="img_prod_guides" alt="Programmed Cell Death" title="View further information about Programmed Cell Death"><p class="lit_title">Programmed Cell Death</p><div class="234501 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/programmed-cell-death-poster-2014.pdf" download="https://resources.tocris.com/pdfs/literature/posters/programmed-cell-death-poster-2014.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/programmed-cell-death-poster-2014.pdf" data-pdfitem="234501" data-title="Programmed Cell Death" target="_blank"><div class="pdf_wording" id="pdf_234501"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="522525" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/522525.jpg" class="img_prod_guides" alt="Rheumatoid Arthritis" title="View further information about Rheumatoid Arthritis"><p class="lit_title">Rheumatoid Arthritis</p><div class="522525 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/rheumatoide-arthritis-poster-2016.pdf" download="https://resources.tocris.com/pdfs/literature/posters/rheumatoide-arthritis-poster-2016.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/rheumatoide-arthritis-poster-2016.pdf" data-pdfitem="522525" data-title="Rheumatoid Arthritis" target="_blank"><div class="pdf_wording" id="pdf_522525"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="630620" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/630620.jpg" class="img_prod_guides" alt="Stem Cell Workflow" title="View further information about Stem Cell Workflow"><p class="lit_title">Stem Cell Workflow</p><div class="630620 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/stem-cell-workflow-poster-v1-2019.pdf" data-pdfitem="630620" data-title="Stem Cell Workflow" target="_blank"><div class="pdf_wording" id="pdf_630620"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div><div class="ind_lit_wrapper ind_lit_wrapper_short" ><div class="ind_lit ind_lit_short" data-itemid="571184" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/571184.jpg?v=2" class="img_prod_guides" alt="Stem Cells" title="View further information about Stem Cells"><p class="lit_title">Stem Cells</p><div class="571184 request_lit"><div class="request"><span class="request_text">Request Copy</span></div></div></div><a href="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" download="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" class="download_pdf" data-download="0" data-url="https://resources.tocris.com/pdfs/literature/posters/stem-cell-differentiation-poster-2022.pdf" data-pdfitem="571184" data-title="Stem Cells" target="_blank"><div class="pdf_wording" id="pdf_571184"><span>Download PDF</span><div class="lit_pdf"></div></div></a></div></div></span><div class="lit_group clearfix" id="130" ><hr/><h3 class="subhead">Scientific Posters</h3><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="659701" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/659701.jpg" class="img_prod_guides" alt="Developing Degraders" title="View further information about Developing Degraders"><p class="lit_title">Developing Degraders</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p659701" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="660812" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/660812.jpg" class="img_prod_guides" alt="Enabling Research By Provision of Chemical Tools" title="View further information about Enabling Research By Provision of Chemical Tools"><p class="lit_title">Enabling Research By Provision of Chemical Tools</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p660812" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="766834" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/766834.jpg" class="img_prod_guides" alt="Novel Live-cell and Fixable Mitochondrial Probes" title="View further information about Novel Live-cell and Fixable Mitochondrial Probes"><p class="lit_title">Novel Live-cell and Fixable Mitochondrial Probes</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p766834" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="634527" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/634527.jpg" class="img_prod_guides" alt="Targeted Protein Degradation" title="View further information about Targeted Protein Degradation"><p class="lit_title">Targeted Protein Degradation</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p634527" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div><div class="ind_lit_wrapper ind_lit_wrapper_tall" ><div class="ind_lit ind_lit_tall" data-itemid="766777" data-is_selected="0"><img src="https://resources.tocris.com/images/literature/posters/regular/766777.jpg" class="img_prod_guides" alt="Validating Targets for TPD Using dTAG" title="View further information about Validating Targets for TPD Using dTAG"><p class="lit_title">Validating Targets for TPD Using dTAG</p><div></div></div><div class="ind_pdf request_pdf" data-itemid="p766777" data-is_selected="0"> <div class="request"><span class="request_pdf_icon"></span><span class="request_text">Request PDF</span></div></div></div></div></div></div><input type="hidden" name="lit_ids" value="234525" /> <button type="submit" id="edit-next-bottom" name="op" value="Continue" class="btn btn-default form-submit">Continue</button> <input type="hidden" name="form_build_id" value="form-41ibSbdNkmXUzBwTeZqyZsadWjqPfhuYxxC8zSxP6DU" /> <input type="hidden" name="form_id" value="literature_request_form" /> </div></form> </div> </section> </div> </div> <footer id="footer_wrapper" class="container-fluid"> <div id="footer_wrapper_container" class="row"> <div id="footer" class="container"> <div id="footer_container" class="row"> <nav class="footer_column footer_column_1 col-xs-12 col-sm-3"> <div class="region region-footer-column-1"> <section id="block-menu-menu-corporate-menu" class="block block-menu clearfix"> <h6 class="block-title">Corporate</h6> <ul class="menu nav"><li class="first leaf"><a href="/about-tocris" id="menu-corporate-menu-14021">About Us</a></li> <li class="leaf"><a href="/about-tocris/careers-at-tocris" id="menu-corporate-menu-14026">Careers</a></li> <li class="leaf"><a href="/about-tocris/tocris-events" id="menu-corporate-menu-14031">Events</a></li> <li class="leaf"><a href="/support/terms-and-conditions-of-sale" id="menu-corporate-menu-591">Terms & Conditions</a></li> <li class="last leaf"><a href="/about-tocris/tocris-in-the-news" id="menu-corporate-menu-594">Tocris in the News</a></li> </ul> </section> </div> </nav> <nav class="footer_column footer_column_2 col-xs-12 col-sm-3"> <div class="region region-footer-column-2"> <section id="block-menu-menu-support-menu" class="block block-menu clearfix"> <h6 class="block-title">Support</h6> <ul class="menu nav"><li class="first leaf"><a href="/support/contact-us" id="menu-support-menu-603">Contact Us</a></li> <li class="leaf"><a href="/support/customer-support" id="menu-support-menu-14036">Customer Support</a></li> <li class="leaf"><a href="/distributors" id="menu-support-menu-601">Distributors</a></li> <li class="leaf"><a href="/about-tocris/licensing" id="menu-support-menu-14041">Licensing</a></li> <li class="leaf"><a href="/resources" id="menu-support-menu-14046">Scientific Resources</a></li> <li class="last leaf"><a href="/support/technical-support" id="menu-support-menu-14051">Technical Support</a></li> </ul> </section> </div> </nav> <nav class="footer_column footer_column_3 col-xs-12 col-sm-3"> <div class="region region-footer-column-3"> <section id="block-menu-menu-brands-menu" class="block block-menu clearfix"> <h6 class="block-title">Bio-Techne Brands</h6> <ul class="menu nav"><li class="first leaf"><a href="https://www.rndsystems.com/" title="" target="_blank" id="menu-brands-menu-605">R&D Systems</a></li> <li class="leaf"><a href="https://www.novusbio.com" title="" target="_blank" id="menu-brands-menu-606">Novus Biologicals</a></li> <li class="leaf"><a href="/" title="" id="menu-brands-menu-607">Tocris Bioscience</a></li> <li class="leaf"><a href="https://www.bio-techne.com/brands/proteinsimple" target="_blank" id="menu-brands-menu-608">ProteinSimple</a></li> <li class="last leaf"><a href="https://acdbio.com" title="" target="_blank" id="menu-brands-menu-9731">ACD</a></li> </ul> </section> </div> </nav> <div class="footer_column footer_column_4 col-xs-12 col-sm-3"> <div class="region region-footer-column-4"> <section id="block-block-2" class="block block-block clearfix"> <h6 class="block-title">Stay Connected</h6> <p>Get the latest news, product updates, and promotions:</p> <p><a class="btn btn-primary" href="/literature/signup" rel="nofollow">Sign Up for E-Alerts</a></p> <p>Follow Tocris:</p> <p><a class="social_link" href="https://www.linkedin.com/company/tocris-bioscience/" target="_blank" rel="nofollow"><span class="icon-linkedin-square">聽</span></a> <a class="social_link" href="https://www.facebook.com/TocrisBioscience/" target="_blank"><span class="icon-facebook-square">聽</span></a> <a class="social_link" href="https://twitter.com/Tocris" target="_blank"><span class="icon-twitter-square">聽</span></a></p> </section> </div> </div> </div> </div> </div> </footer> <div id="copyright_wrapper" class="container-fluid"> <div id="copyright_wrapper_container" class="row"> <div id="copyright" class="container"> <div id="copyright_container" class="row"> <div id="copyright_content" class="col-xs-12"> <p> <div class="region region-copyright"> <section id="block-block-4" class="block block-block clearfix"> © Copyright 2024 Tocris Bioscience. All Rights Reserved. <a href="/support/privacy-and-cookie-policy">Privacy and Cookie Policy</a> | <a href="/sitemap">Site Map</a> </section> </div> </p> </div> </div> </div> </div> </div> <script>var _hmt = _hmt || []; (function() { var hm = document.createElement("script"); hm.async = true; hm.defer = true; hm.src = "//hm.baidu.com/hm.js?7d34c554a46d6206cd64f92f2c696096"; var s = document.getElementsByTagName("script")[0]; s.parentNode.insertBefore(hm, s); })();</script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js_uYOBUFiqvvb4wfxMm9lv6K2nGZsGsre4m_Tbhtd7S0I.js"></script> <script src="https://www.tocris.com/sites/tocris.com/files/js/js_MRdvkC2u4oGsp5wVxBG1pGV5NrCPW3mssHxIn6G9tGE.js"></script> <script type="text/javascript">window.NREUM||(NREUM={});NREUM.info={"beacon":"bam.nr-data.net","licenseKey":"76fb58fb05","applicationID":"788348528,30870807","transactionName":"YFdbZBFZXxdWAhAMVlkdeFMXUV4KGA0NEVxFU01FEV1uFlIQEQBKQ21JUQRd","queueTime":18,"applicationTime":283,"atts":"TBBYEllDTBk=","errorBeacon":"bam.nr-data.net","agent":""}</script></body> </html>