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Search results for: bone substitutes
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text-center" style="font-size:1.6rem;">Search results for: bone substitutes</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">867</span> A Review on Bone Grafting, Artificial Bone Substitutes and Bone Tissue Engineering</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kasun%20Gayashan%20Samarawickrama">Kasun Gayashan Samarawickrama</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone diseases, defects, and fractions are commonly seen in modern life. Since bone is regenerating dynamic living tissue, it will undergo healing process naturally, it cannot recover from major bone injuries, diseases and defects. In order to overcome them, bone grafting technique was introduced. Gold standard was the best method for bone grafting for the past decades. Due to limitations of gold standard, alternative methods have been implemented. Apart from them artificial bone substitutes and bone tissue engineering have become the emerging methods with technology for bone grafting. Many bone diseases and defects will be healed permanently with these promising techniques in future. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20grafting" title="bone grafting">bone grafting</a>, <a href="https://publications.waset.org/abstracts/search?q=gold%20standard" title=" gold standard"> gold standard</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20substitutes" title=" bone substitutes"> bone substitutes</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20tissue%20engineering" title=" bone tissue engineering"> bone tissue engineering</a> </p> <a href="https://publications.waset.org/abstracts/79771/a-review-on-bone-grafting-artificial-bone-substitutes-and-bone-tissue-engineering" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79771.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">299</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">866</span> Viscoelastic Characterization of Bovine Trabecular Bone Samples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Ramirez%20D.%20Edgar">I. Ramirez D. Edgar</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Angeles%20H.%20Jos%C3%A9"> J. Angeles H. José</a>, <a href="https://publications.waset.org/abstracts/search?q=Ruiz%20C.%20Osvaldo"> Ruiz C. Osvaldo</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Jacobo%20A.%20Victor"> H. Jacobo A. Victor</a>, <a href="https://publications.waset.org/abstracts/search?q=Ortiz%20P.%20Armando"> Ortiz P. Armando</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Knowledge of bone mechanical properties is important for bone substitutes design and fabrication, and more efficient prostheses development. The aim of this study is to characterize the viscoelastic behavior of bone specimens, through stress relaxation and fatigue tests performed to trabecular bone samples from bovine femoral heads. Relaxation tests consisted on preloading the samples at five different magnitudes and evaluate them for 1020 seconds, adjusting the results to a KWW mathematical model. Fatigue tests consisted of 700 load cycles and analyze their status at the end of the tests. As a conclusion we have that between relaxation stress and each preload there is linear relation and for samples with initial Young´s modulus greater than 1.5 GPa showed no effects due fatigue test loading cycles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20viscoelasticity" title="bone viscoelasticity">bone viscoelasticity</a>, <a href="https://publications.waset.org/abstracts/search?q=fatigue%20test" title=" fatigue test"> fatigue test</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20relaxation%20test" title=" stress relaxation test"> stress relaxation test</a>, <a href="https://publications.waset.org/abstracts/search?q=trabecular%20bone%20properties" title=" trabecular bone properties"> trabecular bone properties</a> </p> <a href="https://publications.waset.org/abstracts/21146/viscoelastic-characterization-of-bovine-trabecular-bone-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21146.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">489</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">865</span> A Radiographic Survey of Eggshell Powder Effect on Tibial Bone Defect Repair Tested in Dog</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Yadegari">M. Yadegari</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Nourbakhsh"> M. Nourbakhsh</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Arbabzadeh"> N. Arbabzadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The skeletal system injuries are of major importance. In addition, it is recommended to use materials for hard tissue repair in open or closed fractures. It is important to use complex minerals with a beneficial effect on hard tissue repair, stimulating cell growth in the bone. Materials that could help avoid bone fracture inflammatory reaction and speed up bone fracture repair are of utmost importance in the treatment of bone fractures. Similar to minerals, the inner eggshell membrane consists of carbohydrates, lipids, proteins with the high pH, high calcium absorptive capacity and with faster bone fracture repair ability. In the present radiographic survey, eggshell-derived bone graft substitutes were used for bone defect repair in 8 dog tibia, measuring bone density on the day of implant placement and 30 and 60 days after placement. In fact, the result of this study shows the difference in bone growth and misshapen bones between treatment and control sites. Cell growth was adequate in treatment sites and misshapen bones were less frequent here than in control sites. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20repair" title="bone repair">bone repair</a>, <a href="https://publications.waset.org/abstracts/search?q=eggshell%20powder" title=" eggshell powder"> eggshell powder</a>, <a href="https://publications.waset.org/abstracts/search?q=implant" title=" implant"> implant</a>, <a href="https://publications.waset.org/abstracts/search?q=radiography" title=" radiography"> radiography</a> </p> <a href="https://publications.waset.org/abstracts/34008/a-radiographic-survey-of-eggshell-powder-effect-on-tibial-bone-defect-repair-tested-in-dog" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34008.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">322</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">864</span> Suitability Verification of Cellulose Nanowhisker as a Scaffold for Bone Tissue Engineering</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Moon%20Hee%20Jung">Moon Hee Jung</a>, <a href="https://publications.waset.org/abstracts/search?q=Dae%20Seung%20Kim"> Dae Seung Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Sang-Myung%20Jung"> Sang-Myung Jung</a>, <a href="https://publications.waset.org/abstracts/search?q=Gwang%20Heum%20Yoon"> Gwang Heum Yoon</a>, <a href="https://publications.waset.org/abstracts/search?q=Hoo%20Cheol%20Lee"> Hoo Cheol Lee</a>, <a href="https://publications.waset.org/abstracts/search?q=Hwa%20Sung%20Shin"> Hwa Sung Shin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Scaffolds are an important part to support growth and differentiation of osteoblast for regeneration of injured bone in bone tissue engineering. We utilized tunicate cellulose nanowhisker (CNW) as scaffold and developed complex system that can enhance differentiation of osteoblast by applying mechanical stimulation. CNW, a crystal form of cellulose, has high stiffness with a large surface area and is useful as a biomedical material due to its biodegradability and biocompatibility. In this study, CNW was obtained from tunicate extraction and was confirmed for its adhesion, differentiation, growth of osteoblast without cytotoxicity. In addition, osteoblast was successfully differentiated under mechanical stimulation, followed by calcium dependent signaling. In conclusion, we verified suitability of CNW as scaffold and possibility of bone substitutes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=osteoblast" title="osteoblast">osteoblast</a>, <a href="https://publications.waset.org/abstracts/search?q=cellulose%20nanowhisker" title=" cellulose nanowhisker"> cellulose nanowhisker</a>, <a href="https://publications.waset.org/abstracts/search?q=CNW" title=" CNW"> CNW</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20stimulation" title=" mechanical stimulation"> mechanical stimulation</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20tissue%20engineering" title=" bone tissue engineering"> bone tissue engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20substitute" title=" bone substitute"> bone substitute</a> </p> <a href="https://publications.waset.org/abstracts/50870/suitability-verification-of-cellulose-nanowhisker-as-a-scaffold-for-bone-tissue-engineering" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/50870.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">366</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">863</span> Management of Gap Non-Union Following Tumour Resection of the Distal Femur</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rajendra%20Kumar%20Kanojia">Rajendra Kumar Kanojia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Correction of the gap created by the resection of large juxtra-articular tumours of the femur would be difficult to manage, several bone substitutes, bone grafts, and artificial bone granules were tried but the results were not as good as with the distraction osteogensis, by the help of either Ilizarov ring fixator or the mono-rail fixators. We are presenting a small study of five cases of malignant tumours of the distal femur, removed, custom made mega prosthesis was applied and that failed twice in a span of five years. We had no better option left then to apply mono-rail fixator, and start the process of distraction osteogeneis, we got the union, gap was filled with new bone and patient has been made walking in few months. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=distal%20femur%20tumour" title="distal femur tumour">distal femur tumour</a>, <a href="https://publications.waset.org/abstracts/search?q=resection" title=" resection"> resection</a>, <a href="https://publications.waset.org/abstracts/search?q=defect%20non-union" title=" defect non-union"> defect non-union</a>, <a href="https://publications.waset.org/abstracts/search?q=mono-rail%20fixator" title=" mono-rail fixator"> mono-rail fixator</a> </p> <a href="https://publications.waset.org/abstracts/36436/management-of-gap-non-union-following-tumour-resection-of-the-distal-femur" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/36436.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">375</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">862</span> The Effect of the Combination of Mouthwash and Saliva Substitutes on Tooth Erosion: An in Vitro Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Young-Eun%20Jang">Young-Eun Jang</a>, <a href="https://publications.waset.org/abstracts/search?q=Mi-Hye%20Ma"> Mi-Hye Ma</a>, <a href="https://publications.waset.org/abstracts/search?q=Yemi%20Kim"> Yemi Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> As the elderly population increases, the number of patients complaining of dry mouth is also increasing. Elderly people often use mouthwash to prevent periodontal disease. Mouthwash and saliva substitutes with low pH were reported to be able to cause enamel erosion. To the best of our knowledge, there have been no studies showing the effect of mouthwash on patients using saliva substitutes. Therefore, the purpose of this study was to evaluate the effect of the use of mouthwash in combination with saliva substitutes on tooth erosion using a quantitative light-induced fluorescence-digital (QLF-D) system. A total of 96 bovine specimens were embedded in putty blocks and randomly allocated to the following groups with n = 12 each: Group 1, application of mouthwash; Group 2, application of saliva substitutes; Group 3, application of saliva substitutes in combination with mouthwash; and control group, application of saline. The bovine samples were eroded using a demineralization solution and then saliva substitutes and mouthwash were applied according to the groups for 2 weeks. For saliva substitutes, three different products were used; Oasis (Oasis Consumer Health, Cleveland, OH, USA), Xeromia solution (Osstem Pharma Co., Seoul, Korea), and Drymund gel (Dong-A Pharma Co., Seoul, Korea). The pH values of the saliva substitutes were determined using a pH meter. Loss of enamel and root dentin was measured using the QLF-D system immediately after demineralization on the 3rd, 7th, and 14th days. The data were analyzed using repeated measures ANOVA followed by Tukey’s post hoc tests (p < 0.05). Mineral loss in enamel and root dentin was detected when mouthwash and saliva substitutes were used alone, respectively (p < 0.05). Also, when mouthwash was used with saliva substitutes, the mineral loss was observed in enamel and root dentin (p < 0.05). The use of Xeromia and Drymund gel increased mineral loss of enamel significantly compared to the use of Oasis (p < 0.05). However, when Drymund gel and Xeromia were used in combination with mouthwash, mineral loss of enamel was significantly reduced compared to when they were used alone (p < 0.05). The pH values of Drymund gel, Xeromia, Oasis, and mouthwash were 5.5, 5.52, 6.2, and 6.37, respectively. Based on these results, it can be concluded that the use of mouthwash with a higher pH value than that of saliva substitutes could help patients suffering from xerostomia avoid the risk of dental erosion. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=saliva%20substitute" title="saliva substitute">saliva substitute</a>, <a href="https://publications.waset.org/abstracts/search?q=mouthwash" title=" mouthwash"> mouthwash</a>, <a href="https://publications.waset.org/abstracts/search?q=tooth%20erosion" title=" tooth erosion"> tooth erosion</a>, <a href="https://publications.waset.org/abstracts/search?q=dry%20mouth" title=" dry mouth"> dry mouth</a> </p> <a href="https://publications.waset.org/abstracts/156425/the-effect-of-the-combination-of-mouthwash-and-saliva-substitutes-on-tooth-erosion-an-in-vitro-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156425.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">90</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">861</span> Induced Bone Tissue Temperature in Drilling Procedures: A Comparative Laboratory Study with and without Lubrication</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=L.%20Roseiro">L. Roseiro</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Veiga"> C. Veiga</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Maranha"> V. Maranha</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Neto"> A. Neto</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Laraqi"> N. Laraqi</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ba%C3%AFri"> A. Baïri</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Alilat"> N. Alilat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In orthopedic surgery there are various situations in which the surgeon needs to implement methods of cutting and drilling the bone. With this type of procedure the generated friction leads to a localized increase in temperature, which may lead to the bone necrosis. Recognizing the importance of studying this phenomenon, an experimental evaluation of the temperatures developed during the procedure of drilling bone has been done. Additionally the influence of the use of the procedure with / without additional lubrication during drilling of bone has also been done. The obtained results are presented and discussed and suggests an advantage in using additional lubrication as a way to minimize the appearance of bone tissue necrosis during bone drilling procedures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20necrosis" title="bone necrosis">bone necrosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20drilling" title=" bone drilling"> bone drilling</a>, <a href="https://publications.waset.org/abstracts/search?q=thermography" title=" thermography"> thermography</a>, <a href="https://publications.waset.org/abstracts/search?q=surgery" title=" surgery"> surgery</a> </p> <a href="https://publications.waset.org/abstracts/16605/induced-bone-tissue-temperature-in-drilling-procedures-a-comparative-laboratory-study-with-and-without-lubrication" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16605.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">597</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">860</span> Effect of Aerobic Exercise on Estrogen Hormone and Bone Mineral Density in Osteoporotic Women</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noha%20Mohamed%20Abdelhafez%20Dahy">Noha Mohamed Abdelhafez Dahy</a>, <a href="https://publications.waset.org/abstracts/search?q=Azza%20Abd%20El-Aziz"> Azza Abd El-Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=Eman%20Ahmed"> Eman Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Marwa%20El-Sayed"> Marwa El-Sayed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Osteoporosis is a metabolic bone disease characterized by low bone mass, deterioration of bone tissue, and disruption of bone microarchitecture, which leads to compromised bone strength and an increased risk of fracture, commonly it occurs in women 10-15 years after menopause, the mean age of menopause is 51 years. Menopause is natural physiological changes primary because of decline of ovaries function with age which leads to decrease of estrogen hormone production which is the main hormone for bone continuous remodeling for bone density maintenance. Exercise increase stimulation of bone growth to keep bone mass by the effect of the mechanical stimulation, antigravity loading and stress exerted on musculoskeletal muscles. Purpose: This study aimed to determine the effect of aerobic exercise on estrogen hormone and bone mineral density (BMD) in osteoporotic women and the correlation between the estrogen and BMD. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Osteoporosis" title="Osteoporosis">Osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=Postmenopause" title=" Postmenopause"> Postmenopause</a>, <a href="https://publications.waset.org/abstracts/search?q=Aerobic%20exercise" title=" Aerobic exercise"> Aerobic exercise</a>, <a href="https://publications.waset.org/abstracts/search?q=DEXA" title=" DEXA"> DEXA</a>, <a href="https://publications.waset.org/abstracts/search?q=Serum%20Estrogen" title=" Serum Estrogen"> Serum Estrogen</a> </p> <a href="https://publications.waset.org/abstracts/166825/effect-of-aerobic-exercise-on-estrogen-hormone-and-bone-mineral-density-in-osteoporotic-women" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166825.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">88</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">859</span> Human Bone Marrow Stem Cell Behavior on 3D Printed Scaffolds as Trabecular Bone Grafts</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zeynep%20Busra%20Velioglu">Zeynep Busra Velioglu</a>, <a href="https://publications.waset.org/abstracts/search?q=Deniz%20Pulat"> Deniz Pulat</a>, <a href="https://publications.waset.org/abstracts/search?q=Beril%20Demirbakan"> Beril Demirbakan</a>, <a href="https://publications.waset.org/abstracts/search?q=Burak%20Ozcan"> Burak Ozcan</a>, <a href="https://publications.waset.org/abstracts/search?q=Ece%20Bayrak"> Ece Bayrak</a>, <a href="https://publications.waset.org/abstracts/search?q=Cevat%20Erisken"> Cevat Erisken</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone tissue has the ability to perform a wide array of functions including providing posture, load-bearing capacity, protection for the internal organs, initiating hematopoiesis, and maintaining the homeostasis of key electrolytes via calcium/phosphate ion storage. The most common cause for bone defects is extensive trauma and subsequent infection. Bone tissue has the self-healing capability without a scar tissue formation for the majority of the injuries. However, some may result with delayed union or fracture non-union. Such cases include reconstruction of large bone defects or cases of compromised regenerative process as a result of avascular necrosis and osteoporosis. Several surgical methods exist to treat bone defects, including Ilizarov method, Masquelete technique, growth factor stimulation, and bone replacement. Unfortunately, these are technically demanding and come with noteworthy disadvantages such as lengthy treatment duration, adverse effects on the patient’s psychology, repeated surgical procedures, and often long hospitalization times. These limitations associated with surgical techniques make bone substitutes an attractive alternative. Here, it was hypothesized that a 3D printed scaffold will mimic trabecular bone in terms of biomechanical properties and that such scaffolds will support cell attachment and survival. To test this hypothesis, this study aimed at fabricating poly(lactic acid), PLA, structures using 3D printing technology for trabecular bone defects, characterizing the scaffolds and comparing with bovine trabecular bone. Capacity of scaffolds on human bone marrow stem cell (hBMSC) attachment and survival was also evaluated. Cubes with a volume of 1 cm³ having pore sizes of 0.50, 1.00 and 1.25 mm were printed. The scaffolds/grafts were characterized in terms of porosity, contact angle, compressive mechanical properties as well cell response. Porosities of the 3D printed scaffolds were calculated based on apparent densities. For contact angles, 50 µl distilled water was dropped over the surface of scaffolds, and contact angles were measured using ‘Image J’ software. Mechanical characterization under compression was performed on scaffolds and native trabecular bone (bovine, 15 months) specimens using a universal testing machine at a rate of 0.5mm/min. hBMSCs were seeded onto the 3D printed scaffolds. After 3 days of incubation with fully supplemented Dulbecco’s modified Eagle’s medium, the cells were fixed using 2% formaldehyde and glutaraldehyde mixture. The specimens were then imaged under scanning electron microscopy. Cell proliferation was determined by using EZQuant dsDNA Quantitation kit. Fluorescence was measured using microplate reader Spectramax M2 at the excitation and emission wavelengths of 485nm and 535nm, respectively. Findings suggested that porosity of scaffolds with pore dimensions of 0.5mm, 1.0mm and 1.25mm were not affected by pore size, while contact angle and compressive modulus decreased with increasing pore size. Biomechanical characterization of trabecular bone yielded higher modulus values as compared to scaffolds with all pore sizes studied. Cells attached and survived in all surfaces, demonstrating higher proliferation on scaffolds with 1.25mm pores as compared with those of 1mm. Collectively, given lower mechanical properties of scaffolds as compared to native bone, and biocompatibility of the scaffolds, the 3D printed PLA scaffolds of this study appear as candidate substitutes for bone repair and regeneration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=3D%20printing" title="3D printing">3D printing</a>, <a href="https://publications.waset.org/abstracts/search?q=biomechanics" title=" biomechanics"> biomechanics</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20repair" title=" bone repair"> bone repair</a>, <a href="https://publications.waset.org/abstracts/search?q=stem%20cell" title=" stem cell"> stem cell</a> </p> <a href="https://publications.waset.org/abstracts/84495/human-bone-marrow-stem-cell-behavior-on-3d-printed-scaffolds-as-trabecular-bone-grafts" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84495.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">172</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">858</span> Design Improvement of Dental Implant-Based on Bone Remodelling</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Solehuddin%20Shuib">Solehuddin Shuib</a>, <a href="https://publications.waset.org/abstracts/search?q=Koay%20Boon%20Aik"> Koay Boon Aik</a>, <a href="https://publications.waset.org/abstracts/search?q=Zainul%20Ahmad%20Rajion"> Zainul Ahmad Rajion</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There are many types of mechanical failure on the dental implant. In this project, the failure that needs to take into consideration is the bone resorption on the dental implant. Human bone has its ability to remodel after the implantation. As the dental implant is installed into the bone, the bone will detect and change the bone structure to achieve new biomechanical environment. This phenomenon is known as bone remodeling. The objective of the project is to improve the performance of dental implant by using different types of design. These designs are used to analyze and predict the failure of the dental implant by using finite element analysis (FEA) namely ANSYS. The bone is assumed to be fully attached to the implant or cement. Hence, results are then compared with other researchers. The results were presented in the form of Von Mises stress, normal stress, shear stress analysis, and displacement. The selected design will be analyzed further based on a theoretical calculation of bone remodeling on the dental implant. The results have shown that the design constructed passed the failure analysis. Therefore, the selected design is proven to have a stable performance at the recovery stage. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dental%20implant" title="dental implant">dental implant</a>, <a href="https://publications.waset.org/abstracts/search?q=FEA" title=" FEA"> FEA</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20remodeling" title=" bone remodeling"> bone remodeling</a>, <a href="https://publications.waset.org/abstracts/search?q=design" title=" design"> design</a> </p> <a href="https://publications.waset.org/abstracts/19662/design-improvement-of-dental-implant-based-on-bone-remodelling" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19662.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">501</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">857</span> Assessment of the Radiation Absorbed Dose Produced by Lu-177, Ra-223, AC-225 for Metastatic Prostate Cancer in a Bone Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Tajadod">Maryam Tajadod</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The treatment of cancer is one of the main challenges of nuclear medicine; while cancer begins in an organ, such as the breast or prostate, it spreads to the bone, resulting in metastatic bone. In the treatment of cancer with radiotherapy, the determination of the involved tissues’ dose is one of the important steps in the treatment protocol. Comparing absorbed doses for Lu-177 and Ra-223 and Ac-225 in the bone marrow and soft tissue of bone phantom with evaluating energetic emitted particles of these radionuclides is the important aim of this research. By the use of MCNPX computer code, a model for bone phantom was designed and the values of absorbed dose for Ra-223 and Ac-225, which are Alpha emitters & Lu-177, which is a beta emitter, were calculated. As a result of research, in comparing gamma radiation for three radionuclides, Lu-177 released the highest dose in the bone marrow and Ra-223 achieved the lowest level. On the other hand, the result showed that although the figures of absorbed dose for Ra and Ac in the bone marrow are near to each other, Ra spread more energy in cortical bone. Moreover, The alpha component of the Ra-223 and Ac-225 have very little effect on bone marrow and soft tissue than a beta component of the lu-177 and it leaves the highest absorbed dose in the bone where the source is located. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20metastases" title="bone metastases">bone metastases</a>, <a href="https://publications.waset.org/abstracts/search?q=lutetium-177" title=" lutetium-177"> lutetium-177</a>, <a href="https://publications.waset.org/abstracts/search?q=radium-223" title=" radium-223"> radium-223</a>, <a href="https://publications.waset.org/abstracts/search?q=actinium-225" title=" actinium-225"> actinium-225</a>, <a href="https://publications.waset.org/abstracts/search?q=absorbed%20dose" title=" absorbed dose"> absorbed dose</a> </p> <a href="https://publications.waset.org/abstracts/149268/assessment-of-the-radiation-absorbed-dose-produced-by-lu-177-ra-223-ac-225-for-metastatic-prostate-cancer-in-a-bone-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149268.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">112</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">856</span> Evaluation of Biological and Confinement Properties of a Bone Substitute to in Situ Preparation Based on Demineralized Bone Matrix for Bone Tissue Regeneration </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aura%20Maria%20Lopera%20Echavarria">Aura Maria Lopera Echavarria</a>, <a href="https://publications.waset.org/abstracts/search?q=Angela%20Maria%20Lema%20Perez"> Angela Maria Lema Perez</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniela%20Medrano%20David"> Daniela Medrano David</a>, <a href="https://publications.waset.org/abstracts/search?q=Pedronel%20Araque%20Marin"> Pedronel Araque Marin</a>, <a href="https://publications.waset.org/abstracts/search?q=Marta%20Elena%20Londo%C3%B1o%20Lopez"> Marta Elena Londoño Lopez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone regeneration is the process by which the formation of new bone is stimulated. Bone fractures can originate at any time due to trauma, infections, tumors, congenital malformations or skeletal diseases. Currently there are different strategies to treat bone defects that in some cases, regeneration does not occur on its own. That is why they are treated with bone substitutes, which provide a necessary environment for the cells to synthesize new bone. The Demineralized Bone Matrix (DBM) is widely used as a bone implant due to its good properties, such as osteoinduction and bioactivity. However, the use of DBM is limited, because its presentation is powder, which is difficult to implant with precision and is susceptible to migrating to other sites through blood flow. That is why the DBM is commonly incorporated into a variety of vehicles or carriers. The objective of this project is to evaluate the bioactive and confinement properties of a bone substitute based on demineralized bone matrix (DBM). Also, structural and morphological properties were evaluated. Bone substitute was obtained from EIA Biomaterials Laboratory of EIA University and the DBM was facilitated by Tissue Bank Foundation. Morphological and structural properties were evaluated by scanning electron microscopy (SEM), X-ray diffraction (DRX) and Fourier transform infrared spectroscopy with total attenuated reflection (FTIR-ATR). Water absorption capacity and degradation were also evaluated during three months. The cytotoxicity was evaluated by the MTT test. The bioactivity of the bone substitute was evaluated through immersion of the samples in simulated body fluid during four weeks. Confinement tests were performed on tibial fragments of a human donor with bone defects of determined size, to ensure that the substitute remains in the defect despite the continuous flow of fluid. According of the knowledge of the authors, the methodology for evaluating samples in a confined environment has not been evaluated before in real human bones. The morphology of the samples showed irregular surface and presented some porosity. DRX confirmed a semi-crystalline structure. The FTIR-ATR determined the organic and inorganic phase of the sample. The degradation and absorption measurements stablished a loss of 3% and 150% in one month respectively. The MTT showed that the system is not cytotoxic. Apatite clusters formed from the first week were visualized by SEM and confirmed by EDS. These calcium phosphates are necessary to stimulate bone regeneration and thanks to the porosity of the developed material, osteinduction and osteoconduction are possible. The results of the in vitro evaluation of the confinement of the material showed that the migration of the bone filling to other sites is negligible, although the samples were subjected to the passage of simulated body fluid. The bone substitute, putty type, showed stability, is bioactive, non-cytotoxic and has handling properties for specialists at the time of implantation. The obtained system allows to maintain the osteoinductive properties of DBM and it can fill completely fractures in any way; however, it does not provide a structural support, that is, it should only be used to treat fractures without requiring a mechanical load. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20regeneration" title="bone regeneration">bone regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=cytotoxicity" title=" cytotoxicity"> cytotoxicity</a>, <a href="https://publications.waset.org/abstracts/search?q=demineralized%20bone%20matrix" title=" demineralized bone matrix"> demineralized bone matrix</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogel" title=" hydrogel"> hydrogel</a> </p> <a href="https://publications.waset.org/abstracts/122964/evaluation-of-biological-and-confinement-properties-of-a-bone-substitute-to-in-situ-preparation-based-on-demineralized-bone-matrix-for-bone-tissue-regeneration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/122964.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">121</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">855</span> Identification of the Orthotropic Parameters of Cortical Bone under Nanoindentation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=D.%20Remache">D. Remache</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Semaan"> M. Semaan</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Baron"> C. Baron</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Pithioux"> M. Pithioux</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Chabrand"> P. Chabrand</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20M.%20Rossi"> J. M. Rossi</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20L.%20Milan"> J. L. Milan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A good understanding of the mechanical properties of the bone implies a better understanding of its various diseases, such as osteoporosis. Berkovich nanoindentation tests were performed on the human cortical bone to extract its orthotropic parameters. The nanoindentation experiments were then simulated by the finite element method. Different configurations of interactions between the tip indenter and the bone were simulated. The orthotropic parameters of the material were identified by the inverse method for each configuration. The friction effect on the bone mechanical properties was then discussed. It was found that the inverse method using the finite element method is a very efficient method to predict the mechanical behavior of the bone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mechanical%20behavior%20of%20bone" title="mechanical behavior of bone">mechanical behavior of bone</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoindentation" title=" nanoindentation"> nanoindentation</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=inverse%20optimization%20approaches" title=" inverse optimization approaches"> inverse optimization approaches</a> </p> <a href="https://publications.waset.org/abstracts/67986/identification-of-the-orthotropic-parameters-of-cortical-bone-under-nanoindentation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67986.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">388</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">854</span> Preliminary Dosimetric Evaluation of Two New 153Sm Bone Pain Palliative Agents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Yousefnia">H. Yousefnia</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Zolghadri"> S. Zolghadri</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Amraee"> N. Amraee</a>, <a href="https://publications.waset.org/abstracts/search?q=Z.%20Naseri"> Z. Naseri</a>, <a href="https://publications.waset.org/abstracts/search?q=Ar.%20Jalilian"> Ar. Jalilian </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of this study was to calculate the absorbed dose to each human organ for two new Sm-153 bone-seeking agents in order to evaluate their effectiveness in bone pain palliation therapy. In this work, the absorbed dose of 153Sm-TTHMP and 153Sm-PDTMP to each human organ was evaluated based on biodistribution studies in rats by radiation dose assessment resource (RADAR) method. The highest absorbed dose for 153Sm-TTHMP and 153Sm-PDTMP is observed in trabecular bone with 1.844 and 3.167 mGy/MBq, respectively. Bone/red marrow dose ratio, as the target/critical organ dose ratio, for 153Sm-PDTMP is greater than 153Sm-TTHMP and is compatible with 153Sm-EDTMP. The results showed that these bone-seeking agents, specially 153Sm-PDTMP, have considerable characteristics compared to the most clinically used bone pain palliative radiopharmaceutical, and therefore, can be good candidates for bone pain palliation in patients with bone metastasis; however, further biological studies in other mammals are still needed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=internal%20dosimetry" title="internal dosimetry">internal dosimetry</a>, <a href="https://publications.waset.org/abstracts/search?q=PDTMP" title=" PDTMP"> PDTMP</a>, <a href="https://publications.waset.org/abstracts/search?q=153Sm" title=" 153Sm"> 153Sm</a>, <a href="https://publications.waset.org/abstracts/search?q=TTHMP" title=" TTHMP"> TTHMP</a> </p> <a href="https://publications.waset.org/abstracts/18061/preliminary-dosimetric-evaluation-of-two-new-153sm-bone-pain-palliative-agents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18061.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">548</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">853</span> Characterization of Fish Bone Catalyst for Biodiesel Production</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sarina%20Sulaiman">Sarina Sulaiman</a>, <a href="https://publications.waset.org/abstracts/search?q=N.Khairudin"> N.Khairudin </a>, <a href="https://publications.waset.org/abstracts/search?q=P.Jamal"> P.Jamal</a>, <a href="https://publications.waset.org/abstracts/search?q=M.Z.%20Alam"> M.Z. Alam</a>, <a href="https://publications.waset.org/abstracts/search?q=Zaki%20Zainudin"> Zaki Zainudin</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Azmi"> S. Azmi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, fish bone waste was used as a new catalyst for biodiesel production. Instead of discarding the fish bone waste, it will be utilized as a source for catalyst that can provide significant benefit to the environment. Also, it can be substitute as a calcium oxide source instead of using eggshell, crab shell and snail shell. The XRD and SEM analysis proved that calcined fish bone contains calcium oxide, calcium phosphate and hydroxyapatite. The catalyst was characterized using Scanning Electron Microscope (SEM) and X-ray Diffraction (XRD). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calcinations" title="calcinations">calcinations</a>, <a href="https://publications.waset.org/abstracts/search?q=fish%20bone" title=" fish bone"> fish bone</a>, <a href="https://publications.waset.org/abstracts/search?q=transesterification" title=" transesterification"> transesterification</a>, <a href="https://publications.waset.org/abstracts/search?q=waste%20catalyst" title=" waste catalyst"> waste catalyst</a> </p> <a href="https://publications.waset.org/abstracts/7717/characterization-of-fish-bone-catalyst-for-biodiesel-production" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7717.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">304</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">852</span> Ultrasonic Densitometry of Bone Tissue of Jaws and Phalanges of Fingers in Patients after Orthodontic Treatment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Margarita%20Belousova">Margarita Belousova</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The ultrasonic densitometry (RU patent № 2541038) was used to assess the density of the bone tissue in the jaws of patients after orthodontic treatment. In addition, by ultrasonic densitometry assessed the state of the bone tissue in the region III phalanges of middle fingers in above mentioned patients. A comparative study was carried out in healthy volunteers of same age. It was established a significant decrease of the ultrasound wave speed and bone mineral density after active period of orthodontic treatment. Statistically, significant differences in bone mineral density of the fingers by ultrasonic densitometry in both groups of patients were not detected. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=intraoral%20ultrasonic%20densitometry" title="intraoral ultrasonic densitometry">intraoral ultrasonic densitometry</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20tissue%20density%20of%20jaws" title=" bone tissue density of jaws"> bone tissue density of jaws</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20tissue%20density%20of%20phalanges%20of%20fingers" title=" bone tissue density of phalanges of fingers"> bone tissue density of phalanges of fingers</a>, <a href="https://publications.waset.org/abstracts/search?q=orthodontic%20treatment" title=" orthodontic treatment"> orthodontic treatment</a> </p> <a href="https://publications.waset.org/abstracts/54572/ultrasonic-densitometry-of-bone-tissue-of-jaws-and-phalanges-of-fingers-in-patients-after-orthodontic-treatment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54572.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">276</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">851</span> Epidemiology of Bone Hydatidosis in Eastern Libya from 1995 to 2013</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sadek%20A.%20Makhlouf">Sadek A. Makhlouf</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassan%20M.%20Nouh"> Hassan M. Nouh </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bone hydatidosis is an infection in worldwide distribution. Although there is no evidence in literature on Bone Hydatid disease in Libya, we tried to present the first epidemiological study of this disease in Eastern Libya through retrospective study from 1995 to 2013. Our data were collected from 3 hospitals in Eastern Libya particularly the sheep-raising areas with total number of musculoskeletal infection cases of two thousand one hundred ninety-four (2,194). There were five (5) five cases of bone infection, four (4) of it have been diagnosed after more than three (3) months. Our study is comparable to other international study but this type of bone infection need further studies for effective control strategies for all dogs to avoid serious complications that might happened from the delay in diagnosing this type of disease. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20infection" title="bone infection">bone infection</a>, <a href="https://publications.waset.org/abstracts/search?q=hydatidosis" title=" hydatidosis"> hydatidosis</a>, <a href="https://publications.waset.org/abstracts/search?q=Eastern%20Libya" title=" Eastern Libya"> Eastern Libya</a>, <a href="https://publications.waset.org/abstracts/search?q=sheep-raising%20areas" title=" sheep-raising areas"> sheep-raising areas</a> </p> <a href="https://publications.waset.org/abstracts/1638/epidemiology-of-bone-hydatidosis-in-eastern-libya-from-1995-to-2013" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1638.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">413</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">850</span> A Comparison of Implant Stability between Implant Placed without Bone Graft versus with Bone Graft Using Guided Bone Regeneration (GBR) Technique: A Resonance Frequency Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=R.%20Janyaphadungpong">R. Janyaphadungpong</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Pimkhaokham"> A. Pimkhaokham</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This prospective clinical study determined the insertion torque (IT) value and monitored the changes in implant stability quotient (ISQ) values during the 12 weeks healing period from implant placement without bone graft (control group) and with bone graft using the guided bone regeneration (GBR) technique (study group). The relationship between the IT and ISQ values of the implants was also assessed. The control and study groups each consisted of 6 patients with 8 implants per group. The ASTRA TECH Implant System™ EV 4.2 mm in diameter was placed in the posterior mandibular region. In the control group, implants were placed in bone without bone graft, whereas in the study group implants were placed simultaneously with the GBR technique at favorable bone defect. IT (Ncm) of each implant was recorded when fully inserted. ISQ values were obtained from the Osstell® ISQ at the time of implant placement, and at 2, 4, 8, and 12 weeks. No difference in IT was found between groups (P = 0.320). The ISQ values in the control group were significantly higher than in the study group at the time of implant placement and at 4 weeks. There was no significant association between IT and ISQ values either at baseline or after the 12 weeks. At 12 weeks of healing, the control and study groups displayed different trends. Mean ISQ values for the control group decreased over the first 2 weeks and then started to increase. ISQ value increases were statistically significant at 8 weeks and later, whereas mean ISQ values in the study group decreased over the first 4 weeks and then started to increase, with statistical significance after 12 weeks. At 12 weeks, all implants achieved osseointegration with mean ISQ values over the threshold value (ISQ>70). These results indicated that implants, in which guided bone regeneration technique was performed during implant placement for treating favorable bone defects, were as predictable as implants placed without bone graft. However, loading in implants placed with the GBR technique for correcting favorable bone defects should be performed after 12 weeks of healing to ensure implant stability and osseointegration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dental%20implant" title="dental implant">dental implant</a>, <a href="https://publications.waset.org/abstracts/search?q=favorable%20bone%20defect" title=" favorable bone defect"> favorable bone defect</a>, <a href="https://publications.waset.org/abstracts/search?q=guided%20bone%20regeneration%20technique" title=" guided bone regeneration technique"> guided bone regeneration technique</a>, <a href="https://publications.waset.org/abstracts/search?q=implant%20stability" title=" implant stability"> implant stability</a> </p> <a href="https://publications.waset.org/abstracts/62198/a-comparison-of-implant-stability-between-implant-placed-without-bone-graft-versus-with-bone-graft-using-guided-bone-regeneration-gbr-technique-a-resonance-frequency-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62198.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">296</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">849</span> Mechanical Cortical Bone Characterization with the Finite Element Method Based Inverse Method</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Djamel%20Remache">Djamel Remache</a>, <a href="https://publications.waset.org/abstracts/search?q=Marie%20Semaan"> Marie Semaan</a>, <a href="https://publications.waset.org/abstracts/search?q=C%C3%A9cile%20Baron"> Cécile Baron</a>, <a href="https://publications.waset.org/abstracts/search?q=Martine%20Pithioux"> Martine Pithioux</a>, <a href="https://publications.waset.org/abstracts/search?q=Patrick%20Chabrand"> Patrick Chabrand</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean-Marie%20Rossi"> Jean-Marie Rossi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jean-Louis%20Milan"> Jean-Louis Milan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cortical bone is a complex multi-scale structure. Even though several works have contributed significantly to understanding its mechanical behavior, this behavior remains poorly understood. Nanoindentation testing is one of the primary testing techniques for the mechanical characterization of bone at small scales. The purpose of this study was to provide new nanoindentation data of cortical bovine bone in different directions and at different bone microstructures (osteonal, interstitial and laminar bone), and then to identify anisotropic properties of samples with FEM (finite element method) based inverse method. Experimentally and numerical results were compared. Experimental and numerical results were compared. The results compared were in good agreement. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mechanical%20behavior%20of%20bone" title="mechanical behavior of bone">mechanical behavior of bone</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoindentation" title=" nanoindentation"> nanoindentation</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=inverse%20optimization%20approach" title=" inverse optimization approach"> inverse optimization approach</a> </p> <a href="https://publications.waset.org/abstracts/65925/mechanical-cortical-bone-characterization-with-the-finite-element-method-based-inverse-method" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65925.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">336</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">848</span> Relation between Initial Stability of the Dental Implant and Bone-Implant Contact Level</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jui-Ting%20Hsu">Jui-Ting Hsu</a>, <a href="https://publications.waset.org/abstracts/search?q=Heng-Li%20Huang"> Heng-Li Huang</a>, <a href="https://publications.waset.org/abstracts/search?q=Ming-Tzu%20Tsai"> Ming-Tzu Tsai</a>, <a href="https://publications.waset.org/abstracts/search?q=Kuo-Chih%20Su"> Kuo-Chih Su</a>, <a href="https://publications.waset.org/abstracts/search?q=Lih-Jyh%20Fuh"> Lih-Jyh Fuh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The objectives of this study were to measure the initial stability of the dental implant (ISQ and PTV) in the artificial foam bone block with three different quality levels. In addition, the 3D bone to implant contact percentage (BIC%) was measured based on the micro-computed tomography images. Furthermore, the relation between the initial stability of dental implant (ISQ and PTV) and BIC% were calculated. The experimental results indicated that enhanced the material property of the artificial foam bone increased the initial stability of the dental implant. The Pearson’s correlation coefficient between the BIC% and the two approaches (ISQ and PTV) were 0.652 and 0.745. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dental%20implant" title="dental implant">dental implant</a>, <a href="https://publications.waset.org/abstracts/search?q=implant%20stability%20quotient" title=" implant stability quotient"> implant stability quotient</a>, <a href="https://publications.waset.org/abstracts/search?q=peak%20insertion%20torque" title=" peak insertion torque"> peak insertion torque</a>, <a href="https://publications.waset.org/abstracts/search?q=bone-implant%20contact" title=" bone-implant contact"> bone-implant contact</a>, <a href="https://publications.waset.org/abstracts/search?q=micro-computed%20tomography" title=" micro-computed tomography"> micro-computed tomography</a> </p> <a href="https://publications.waset.org/abstracts/24176/relation-between-initial-stability-of-the-dental-implant-and-bone-implant-contact-level" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24176.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">579</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">847</span> Alteration of Bone Strength in Osteoporosis of Mouse Femora: Computational Study Based on Micro CT Images</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Changsoo%20Chon">Changsoo Chon</a>, <a href="https://publications.waset.org/abstracts/search?q=Sangkuy%20Han"> Sangkuy Han</a>, <a href="https://publications.waset.org/abstracts/search?q=Donghyun%20Seo"> Donghyun Seo</a>, <a href="https://publications.waset.org/abstracts/search?q=Jihyung%20Park"> Jihyung Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Bokku%20Kang"> Bokku Kang</a>, <a href="https://publications.waset.org/abstracts/search?q=Hansung%20Kim"> Hansung Kim</a>, <a href="https://publications.waset.org/abstracts/search?q=Keyoungjin%20Chun"> Keyoungjin Chun</a>, <a href="https://publications.waset.org/abstracts/search?q=Cheolwoong%20Ko"> Cheolwoong Ko</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The purpose of the study is to develop a finite element model based on 3D bone structural images of Micro-CT and to analyze the stress distribution for the osteoporosis mouse femora. In this study, results of finite element analysis show that the early osteoporosis of mouse model decreased a bone density in trabecular region; however, the bone density in cortical region increased. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=micro-CT" title="micro-CT">micro-CT</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20analysis" title=" finite element analysis"> finite element analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis"> osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20strength" title=" bone strength"> bone strength</a> </p> <a href="https://publications.waset.org/abstracts/48362/alteration-of-bone-strength-in-osteoporosis-of-mouse-femora-computational-study-based-on-micro-ct-images" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48362.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">363</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">846</span> Preparation and Characterization of Activated Carbon from Animal Bone</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Getenet%20Aseged%20Zeleke">Getenet Aseged Zeleke</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this project was to study the synthesis of activated carbon from low-cost animal beef and the characterization of the product obtained. The bone was carbonized in an inert atmosphere at three different temperatures (500°C, 700oC and 900°C) in an electric furnace, followed by activation with hydrochloric acid. The activated animal bone charcoals obtained were characterized by using scanning electron microscopy (SEM)to observe the effect of activation compared to the unactivated bone charcoal. The following parameters were also determined: ash content, moisture content, volatile content, fixed carbon, pH, pore volume and bulk (apparent) density. The characterization result showed that the activated bone charcoal has good properties and is compared favorably with other reference activated carbons. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bones" title="bones">bones</a>, <a href="https://publications.waset.org/abstracts/search?q=carbonization" title=" carbonization"> carbonization</a>, <a href="https://publications.waset.org/abstracts/search?q=activation" title=" activation"> activation</a>, <a href="https://publications.waset.org/abstracts/search?q=characterization" title=" characterization"> characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=activated%20carbon" title=" activated carbon"> activated carbon</a> </p> <a href="https://publications.waset.org/abstracts/166891/preparation-and-characterization-of-activated-carbon-from-animal-bone" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166891.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">85</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">845</span> Reconstructing Calvarial Bone Lesions Using PHBV Scaffolds and Cord Blood Mesenchymal Stem Cells in Rat</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hamed%20Hosseinkazemi">Hamed Hosseinkazemi</a>, <a href="https://publications.waset.org/abstracts/search?q=Esmaeil%20Biazar"> Esmaeil Biazar </a> </p> <p class="card-text"><strong>Abstract:</strong></p> For tissue engineering of bone, anatomical and operational reconstructions of damaged tissue seem to be vital. This is done via reconstruction of bone and appropriate biological joint with bone tissues of damaged areas. In this study the condition of biodegradable bed Nanofibrous PHBV and USSC cells were used to accelerate bone repair of damaged area. Hollow nanofabrication scaffold of damageable life was designed as PHBV by electrospinning and via determining the best factors such as the kind and amount of solvent, specific volume and rate. The separation of osseous tissue infiltration and evaluating its nature by flow cytometrocical analysis was done. Animal test including USSC as well as PHBV condition in the damaged bone was done in the rat. After 8 weeks the implanted area was analyzed using CT scan and was sent to histopathology ward. Finally, the rate and quality of reconstruction were determined after H and E coloring. Histomorphic analysis indicated a statistically significant difference between the experimental group of PHBV, USSC+PHBV and control group. Besides, the histopathologic analysis showed that bone reconstruction rate was high in the area containing USSC and PHBV, compared with area having PHBV and control group and consequently the reconstruction quality of bones and the relationship between the new bone tissues and surrounding bone tissues were high too. Using PHBR scaffold and USSC together could be useful in the amending of wide range of bone lesion. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20lesion" title="bone lesion">bone lesion</a>, <a href="https://publications.waset.org/abstracts/search?q=nanofibrous%20PHBV" title=" nanofibrous PHBV"> nanofibrous PHBV</a>, <a href="https://publications.waset.org/abstracts/search?q=stem%20cells" title=" stem cells"> stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=umbilical%20cord%20blood" title=" umbilical cord blood"> umbilical cord blood</a> </p> <a href="https://publications.waset.org/abstracts/21192/reconstructing-calvarial-bone-lesions-using-phbv-scaffolds-and-cord-blood-mesenchymal-stem-cells-in-rat" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21192.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">318</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">844</span> Stress-Strain Relation for Human Trabecular Bone Based on Nanoindentation Measurements</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marek%20Pawlikowski">Marek Pawlikowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Krzysztof%20Jankowski"> Krzysztof Jankowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Konstanty%20Skalski"> Konstanty Skalski</a>, <a href="https://publications.waset.org/abstracts/search?q=Anna%20Makuch"> Anna Makuch</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nanoindentation or depth-sensing indentation (DSI) technique has proven to be very useful to measure mechanical properties of various tissues at a micro-scale. Bone tissue, both trabecular and cortical one, is one of the most commonly tested tissues by means of DSI. Most often such tests on bone samples are carried out to compare the mechanical properties of lamellar and interlamellar bone, osteonal bone as well as compact and cancellous bone. In the paper, a relation between stress and strain for human trabecular bone is presented. The relation is based on the results of nanoindentation tests. The formulation of a constitutive model for human trabecular bone is based on nanoindentation tests. In the study, the approach proposed by Olivier-Pharr is adapted. The tests were carried out on samples of trabecular tissue extracted from human femoral heads. The heads were harvested during surgeries of artificial hip joint implantation. Before samples preparation, the heads were kept in 95% alcohol in temperature 4 Celsius degrees. The cubic samples cut out of the heads were stored in the same conditions. The dimensions of the specimens were 25 mm x 25 mm x 20 mm. The number of 20 samples have been tested. The age range of donors was between 56 and 83 years old. The tests were conducted with the indenter spherical tip of the diameter 0.200 mm. The maximum load was P = 500 mN and the loading rate 500 mN/min. The data obtained from the DSI tests allows one only to determine bone behoviour in terms of nanoindentation force vs. nanoindentation depth. However, it is more interesting and useful to know the characteristics of trabecular bone in the stress-strain domain. This allows one to simulate trabecular bone behaviour in a more realistic way. The stress-strain curves obtained in the study show relation between the age and the mechanical behaviour of trabecular bone. It was also observed that the bone matrix of trabecular tissue indicates an ability of energy absorption. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=constitutive%20model" title="constitutive model">constitutive model</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20behaviour" title=" mechanical behaviour"> mechanical behaviour</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoindentation" title=" nanoindentation"> nanoindentation</a>, <a href="https://publications.waset.org/abstracts/search?q=trabecular%20bone" title=" trabecular bone"> trabecular bone</a> </p> <a href="https://publications.waset.org/abstracts/74950/stress-strain-relation-for-human-trabecular-bone-based-on-nanoindentation-measurements" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74950.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">221</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">843</span> Benign Osteoblastoma of the Mandible Resection and Replacement of the Defects with Decellularized Cattle Bone Scaffold with Mesenchymal Bone Marrow Stem Cells</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20Mardaleishvili">K. Mardaleishvili</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Loladze"> G. Loladze</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Shatirishivili"> G. Shatirishivili</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Chakhunashvili"> D. Chakhunashvili</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Vishnevskaya"> A. Vishnevskaya</a>, <a href="https://publications.waset.org/abstracts/search?q=Z.%20Kakabadze"> Z. Kakabadze</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Benign osteoblastoma is a benign tumor of the bone, usually affecting the vertebrae and long tubular bones. It is a rarely seen tumor of the facial bones. The authors present a case of a 28-year-old male patient with a tumor in mandibular body. The lesion was radically resected and histological analysis of the specimen demonstrated features typical of a benign osteoblastoma. The defect of the jaw was reconstructed with titanium implants and decellularized and lyophilized cattle bone matrix with mesenchymal bone marrow stem cells transplantation. This presentation describes the procedures for rehabilitating a patient with decellularized bone scaffold in the region of the face, recovering the facial contours and esthetics of the patient. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=facial%20bones" title="facial bones">facial bones</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoblastoma" title=" osteoblastoma"> osteoblastoma</a>, <a href="https://publications.waset.org/abstracts/search?q=stem%20cells" title=" stem cells"> stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=transplantation" title=" transplantation"> transplantation</a> </p> <a href="https://publications.waset.org/abstracts/21112/benign-osteoblastoma-of-the-mandible-resection-and-replacement-of-the-defects-with-decellularized-cattle-bone-scaffold-with-mesenchymal-bone-marrow-stem-cells" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21112.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">421</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">842</span> Influence of Modified and Unmodified Cow Bone on the Mechanical Properties of Reinforced Polyester Composites for Biomedical Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20O.%20Oladele">I. O. Oladele</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20A.%20Omotoyinbo"> J. A. Omotoyinbo</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20M.%20Okoro"> A. M. Okoro</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20G.%20Okikiola"> A. G. Okikiola</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20L.%20Olajide"> J. L. Olajide</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This work was carried out to investigate comparatively the effects of modified and unmodified cow bone particles on the mechanical properties of polyester matrix composites in order to investigate the suitability of the materials as biomaterial. Cow bones were procured from an abattoir, sun dried for 4 weeks and crushed. The crushed bones were divided into two, where one part was turned to ash while the other part was pulverized with laboratory ball mill before the two grades were sieved using 75 µm sieve size. Bone ash and bone particle reinforced tensile and flexural composite samples were developed from pre-determined proportions of 2, 4, 6, and 8 %. The samples after curing were stripped from the moulds and were allowed to further cure for 3 weeks before tensile and flexural tests were performed on them. The tensile test result showed that, 8 wt % bone particle reinforced polyester composites has higher tensile properties except for modulus of elasticity where 8 wt % bone ash particle reinforced composites has higher value while for flexural test, bone ash particle reinforced composites demonstrate the best flexural properties. The results show that these materials are structurally compatible. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biomedical" title="biomedical">biomedical</a>, <a href="https://publications.waset.org/abstracts/search?q=composites" title=" composites"> composites</a>, <a href="https://publications.waset.org/abstracts/search?q=cow%20bone" title=" cow bone"> cow bone</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20properties" title=" mechanical properties"> mechanical properties</a>, <a href="https://publications.waset.org/abstracts/search?q=polyester" title=" polyester"> polyester</a>, <a href="https://publications.waset.org/abstracts/search?q=reinforcement" title=" reinforcement"> reinforcement</a> </p> <a href="https://publications.waset.org/abstracts/47045/influence-of-modified-and-unmodified-cow-bone-on-the-mechanical-properties-of-reinforced-polyester-composites-for-biomedical-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47045.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">279</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">841</span> Inverse Mode Shape Problem of Hand-Arm Vibration (Humerus Bone) for Bio-Dynamic Response Using Varying Boundary Conditions</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ajay%20R">Ajay R</a>, <a href="https://publications.waset.org/abstracts/search?q=Rammohan%20B"> Rammohan B</a>, <a href="https://publications.waset.org/abstracts/search?q=Sridhar%20K%20S%20S"> Sridhar K S S</a>, <a href="https://publications.waset.org/abstracts/search?q=Gurusharan%20%20N"> Gurusharan N</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The objective of the work is to develop a numerical method to solve the inverse mode shape problem by determining the cross-sectional area of a structure for the desired mode shape via the vibration response study of the humerus bone, which is in the form of a cantilever beam with anisotropic material properties. The humerus bone is the long bone in the arm that connects the shoulder to the elbow. The mode shape is assumed to be a higher-order polynomial satisfying a prescribed set of boundary conditions to converge the numerical algorithm. The natural frequency and the mode shapes are calculated for different boundary conditions to find the cross-sectional area of humerus bone from Eigenmode shape with the aid of the inverse mode shape algorithm. The cross-sectional area of humerus bone validates the mode shapes of specific boundary conditions. The numerical method to solve the inverse mode shape problem is validated in the biomedical application by finding the cross-sectional area of a humerus bone in the human arm. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Cross-sectional%20area" title="Cross-sectional area">Cross-sectional area</a>, <a href="https://publications.waset.org/abstracts/search?q=Humerus%20bone" title=" Humerus bone"> Humerus bone</a>, <a href="https://publications.waset.org/abstracts/search?q=Inverse%20mode%20shape%20problem" title=" Inverse mode shape problem"> Inverse mode shape problem</a>, <a href="https://publications.waset.org/abstracts/search?q=Mode%20shape" title=" Mode shape"> Mode shape</a> </p> <a href="https://publications.waset.org/abstracts/125654/inverse-mode-shape-problem-of-hand-arm-vibration-humerus-bone-for-bio-dynamic-response-using-varying-boundary-conditions" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/125654.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">127</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">840</span> Development of an Artificial Ear for Bone-Conducted Objective Occlusion Measurement</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yu%20Luan">Yu Luan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The bone-conducted objective occlusion effect (OE) is characterized by a discomforting sensation of fullness experienced in an occluded ear. This phenomenon arises from various external stimuli, such as human speech, chewing, and walking, which generate vibrations transmitted through the body to the ear canal walls. The bone-conducted OE occurs due to the pressure build-up inside the occluded ear caused by sound radiating into the ear canal cavity from its walls. In the hearing aid industry, artificial ears are utilized as a tool for developing hearing aids. However, the currently available commercial artificial ears primarily focus on pure acoustics measurements, neglecting the bone-conducted vibration aspect. This research endeavors to develop an artificial ear specifically designed for bone-conducted occlusion measurements. Finite element analysis (FEA) modeling has been employed to gain insights into the behavior of the artificial ear. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20ear" title="artificial ear">artificial ear</a>, <a href="https://publications.waset.org/abstracts/search?q=bone%20conducted%20vibration" title=" bone conducted vibration"> bone conducted vibration</a>, <a href="https://publications.waset.org/abstracts/search?q=occlusion%20measurement" title=" occlusion measurement"> occlusion measurement</a>, <a href="https://publications.waset.org/abstracts/search?q=finite%20element%20modeling" title=" finite element modeling"> finite element modeling</a> </p> <a href="https://publications.waset.org/abstracts/168626/development-of-an-artificial-ear-for-bone-conducted-objective-occlusion-measurement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/168626.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">87</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">839</span> Preservation of Phenytoin and Sodium Valproate Induced Bone Loss by Raloxifene through Modulating Serum Estradiol and TGF-β3 Content in Bone of Female Mice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Divya%20Vohora">Divya Vohora</a>, <a href="https://publications.waset.org/abstracts/search?q=Md.%20Jamir%20Anwar"> Md. Jamir Anwar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Antiepileptic drugs (AEDs)-induced adverse consequences on bone are now well recognized. Despite this, there is limited data on the effect of anti-osteoporotic therapies on AEDs-induced bone loss. Both phenytoin (PHT) and sodium valproate (SVP) inhibit human aromatase enzyme and stimulate microsomal catabolism of oestrogens. Estrogen deficiency states are known to reduce the deposition of transforming growth factor-β (TGF-β3), a bone matrix protein, having anti-osteoclastic property. Thus, an attempt was made to investigate the effect of raloxifene, a selective oestrogen receptor modulator, in comparison with CVD supplementation, on PHT and SVP-induced alterations in bone in mice. Further, the effect of raloxifene on seizures and on the antiepileptic efficacy of AEDs was also investigated. Swiss strains of female mice were treated with PHT (35 mg/kg, p.o.) and SVP (300 mg/kg, p.o.) for 120 days to induce bone loss as evidenced by reduced bone mineral density (BMD) and altered bone turnover markers in lumbar bones (alkaline phosphatase, tartarate resistant acid phosphatase, hydroxyproline) and urine (calcium). The bone loss was accompanied by reduced serum estradiol levels and bone TGF-β3 content. Preventive and curative treatment with raloxifene ameliorated bony alterations and was more effective than CVD. Deprived estrogen levels (that in turn reduced lumbar TGF-β3 content) following PHT and SVP, thus, might represent one of the various mechanisms of AEDs-induced bone loss. Raloxifene preserved the bony changes without interfering with their antiepileptic efficacy, and hence raloxifene could be a potential therapeutic option in the management of PHT and SVP-induced bone disease if clinically approved. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antiepileptic%20drugs" title="antiepileptic drugs">antiepileptic drugs</a>, <a href="https://publications.waset.org/abstracts/search?q=osteoporosis" title=" osteoporosis"> osteoporosis</a>, <a href="https://publications.waset.org/abstracts/search?q=raloxifene" title=" raloxifene"> raloxifene</a>, <a href="https://publications.waset.org/abstracts/search?q=TGF-%CE%B23" title=" TGF-β3"> TGF-β3</a> </p> <a href="https://publications.waset.org/abstracts/16217/preservation-of-phenytoin-and-sodium-valproate-induced-bone-loss-by-raloxifene-through-modulating-serum-estradiol-and-tgf-v3-content-in-bone-of-female-mice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16217.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">345</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">838</span> Differentiated Thyroid Cancer Presenting with Solitary Bony Metastases to the Frontal Bone of the Skull</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Christy%20M.%20Moen">Christy M. Moen</a>, <a href="https://publications.waset.org/abstracts/search?q=Richard%20B.%20Townsley"> Richard B. Townsley</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Metastasis to the frontal bone in thyroid cancer is extremely rare. A literature review found only six cases of thyroid cancer that metastasised to the frontal bone, with two of those involving further bone sites. Case Report: The patient was originally referred to the Oral and Maxillofacial Surgery team with an isolated mass on her forehead. Biopsies were performed, which showed this was likely a metastatic deposit from thyroid cancer. CT-PET scan showed this was an isolated lesion. The patient had a total thyroidectomy, and the forehead lesion was managed with radiotherapy. On interval scanning, the patient’s bony lesion had increased in size and had new lung nodules, which likely represented further metastasis. Conclusion: Isolated bony metastases to the frontal bone are rare. An important clinical principle to remember is that a bony metastasis from an unknown primary is more likely than primary bone cancer. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cancer" title="cancer">cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=thyroid" title=" thyroid"> thyroid</a>, <a href="https://publications.waset.org/abstracts/search?q=head%20and%20neck" title=" head and neck"> head and neck</a>, <a href="https://publications.waset.org/abstracts/search?q=surgery" title=" surgery"> surgery</a> </p> <a href="https://publications.waset.org/abstracts/138043/differentiated-thyroid-cancer-presenting-with-solitary-bony-metastases-to-the-frontal-bone-of-the-skull" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138043.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads 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