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imprinted polymer</title> <meta name="description" content="Search results for: molecularly imprinted polymer"> <meta name="keywords" content="molecularly imprinted polymer"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="molecularly imprinted polymer"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 1544</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: molecularly imprinted polymer</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1544</span> Synthesis and Characterization of Molecularly Imprinted Polymer as a New Adsorbent for the Removal of Pyridine from Organic Medium</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Opeyemi%20Elujulo">Opeyemi Elujulo</a>, <a href="https://publications.waset.org/abstracts/search?q=Aderonke%20Okoya"> Aderonke Okoya</a>, <a href="https://publications.waset.org/abstracts/search?q=Kehinde%20Awokoya"> Kehinde Awokoya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Molecularly imprinted polymers (MIP) for the adsorption of pyridine (PYD) was obtained from PYD (the template), styrene (the functional monomer), divinyl benzene (the crosslinker), benzoyl peroxide (the initiator), and water (the porogen). When the template was removed by solvent extraction, imprinted binding sites were left in the polymer material that are capable of selectively rebinding the target molecule. The material was characterized by Fourier transform infrared spectroscopy and differential scanning calorimetry. Batch adsorption experiments were performed to study the adsorption of the material in terms of adsorption kinetics, isotherms, and thermodynamic parameters. The results showed that the imprinted polymer exhibited higher affinity for PYD compared to non-imprinted polymer (NIP). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer" title="molecularly imprinted polymer">molecularly imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=bulk%20polymerization" title=" bulk polymerization"> bulk polymerization</a>, <a href="https://publications.waset.org/abstracts/search?q=environmental%20pollutant" title=" environmental pollutant"> environmental pollutant</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption" title=" adsorption"> adsorption</a> </p> <a href="https://publications.waset.org/abstracts/129920/synthesis-and-characterization-of-molecularly-imprinted-polymer-as-a-new-adsorbent-for-the-removal-of-pyridine-from-organic-medium" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/129920.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">142</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1543</span> Development of an Aptamer-Molecularly Imprinted Polymer Based Electrochemical Sensor to Detect Pathogenic Bacteria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Meltem%20Agar">Meltem Agar</a>, <a href="https://publications.waset.org/abstracts/search?q=Maisem%20Laabei"> Maisem Laabei</a>, <a href="https://publications.waset.org/abstracts/search?q=Hannah%20Leese"> Hannah Leese</a>, <a href="https://publications.waset.org/abstracts/search?q=Pedro%20Estrela"> Pedro Estrela</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pathogenic bacteria and the diseases they cause have become a global problem. Their early detection is vital and can only be possible by detecting the bacteria causing the disease accurately and rapidly. Great progress has been made in this field with the use of biosensors. Molecularly imprinted polymers have gain broad interest because of their excellent properties over natural receptors, such as being stable in a variety of conditions, inexpensive, biocompatible and having long shelf life. These properties make molecularly imprinted polymers an attractive candidate to be used in biosensors. In this study it is aimed to produce an aptamer-molecularly imprinted polymer based electrochemical sensor by utilizing the properties of molecularly imprinted polymers coupled with the enhanced specificity offered by DNA aptamers. These ‘apta-MIP’ sensors were used for the detection of Staphylococcus aureus and Escherichia coli. The experimental parameters for the fabrication of sensor were optimized, and detection of the bacteria was evaluated via Electrochemical Impedance Spectroscopy. Sensitivity and selectivity experiments were conducted. Furthermore, molecularly imprinted polymer only and aptamer only electrochemical sensors were produced separately, and their performance were compared with the electrochemical sensor produced in this study. Aptamer-molecularly imprinted polymer based electrochemical sensor showed good sensitivity and selectivity in terms of detection of Staphylococcus aureus and Escherichia coli. The performance of the sensor was assessed in buffer solution and tap water. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aptamer" title="aptamer">aptamer</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical%20sensor" title=" electrochemical sensor"> electrochemical sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=staphylococcus%20aureus" title=" staphylococcus aureus"> staphylococcus aureus</a>, <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer" title=" molecularly imprinted polymer"> molecularly imprinted polymer</a> </p> <a href="https://publications.waset.org/abstracts/171368/development-of-an-aptamer-molecularly-imprinted-polymer-based-electrochemical-sensor-to-detect-pathogenic-bacteria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171368.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">118</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1542</span> Multi-Template Molecularly Imprinted Polymer: Synthesis, Characterization and Removal of Selected Acidic Pharmaceuticals from Wastewater</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lawrence%20Mzukisi%20Madikizela">Lawrence Mzukisi Madikizela</a>, <a href="https://publications.waset.org/abstracts/search?q=Luke%20Chimuka"> Luke Chimuka</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Removal of organics from wastewater offers a better water quality, therefore, the purpose of this work was to investigate the use of molecularly imprinted polymer (MIP) for the elimination of selected organics from water. A multi-template MIP for the adsorption of naproxen, ibuprofen and diclofenac was synthesized using a bulk polymerization method. A MIP was synthesized at 70°C by employing 2-vinylpyridine, ethylene glycol dimethacrylate, toluene and 1,1’-azobis-(cyclohexanecarbonitrile) as functional monomer, cross-linker, porogen and initiator, respectively. Thermogravimetric characterization indicated that the polymer backbone collapses at 250°C and scanning electron microscopy revealed the porous and roughness nature of the MIP after elution of templates. The performance of the MIP in aqueous solutions was evaluated by optimizing several adsorption parameters. The optimized adsorption conditions were 50 mg of MIP, extraction time of 10 min, a sample pH of 4.6 and the initial concentration of 30 mg/L. The imprinting factors obtained for naproxen, ibuprofen and diclofenac were 1.25, 1.42, and 2.01, respectively. The order of selectivity for the MIP was; diclofenac > ibuprofen > naproxen. MIP showed great swelling in water with an initial swelling rate of 2.62 g/(g min). The synthesized MIP proved to be able to adsorb naproxen, ibuprofen and diclofenac from contaminated deionized water, wastewater influent and effluent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adsorption" title="adsorption">adsorption</a>, <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer" title=" molecularly imprinted polymer"> molecularly imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=multi%20template" title=" multi template"> multi template</a>, <a href="https://publications.waset.org/abstracts/search?q=pharmaceuticals" title=" pharmaceuticals"> pharmaceuticals</a> </p> <a href="https://publications.waset.org/abstracts/43263/multi-template-molecularly-imprinted-polymer-synthesis-characterization-and-removal-of-selected-acidic-pharmaceuticals-from-wastewater" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43263.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">303</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1541</span> Fabrication of a New Electrochemical Sensor Based on New Nanostructured Molecularly Imprinted Polypyrrole for Selective and Sensitive Determination of Morphine</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samaneh%20Nabavi">Samaneh Nabavi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hadi%20Shirzad"> Hadi Shirzad</a>, <a href="https://publications.waset.org/abstracts/search?q=Arash%20Ghoorchian"> Arash Ghoorchian</a>, <a href="https://publications.waset.org/abstracts/search?q=Maryam%20Shanesaz"> Maryam Shanesaz</a>, <a href="https://publications.waset.org/abstracts/search?q=Reza%20Naderi"> Reza Naderi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Morphine (MO), the most effective painkiller, is considered the reference by which analgesics are assessed. It is very necessary for the biomedical applications to detect and maintain the MO concentrations in the blood and urine with in safe ranges. To date, there are many expensive techniques for detecting MO. Recently, many electrochemical sensors for direct determination of MO were constructed. The molecularly imprinted polymer (MIP) is a polymeric material, which has a built-in functionality for the recognition of a particular chemical substance with its complementary cavity.This paper reports a sensor for MO using a combination of a molecularly imprinted polymer (MIP) and differential-pulse voltammetry (DPV). Electropolymerization of MO doped polypyrrole yielded poor quality, but a well-doped, nanostructure and increased impregnation has been obtained in the pH=12. Above a pH of 11, MO is in the anionic forms. The effect of various experimental parameters including pH, scan rate and accumulation time on the voltammetric response of MO was investigated. At the optimum conditions, the concentration of MO was determined using DPV in a linear range of 7.07 × 10−6 to 2.1 × 10−4 mol L−1 with a correlation coefficient of 0.999, and a detection limit of 13.3 × 10-8 mol L−1, respectively. The effect of common interferences on the current response of MO namely ascorbic acid (AA) and uric acid (UA) is studied. The modified electrode can be used for the determination of MO spiked into urine samples, and excellent recovery results were obtained. The nanostructured polypyrrole films were characterized by field emission scanning electron microscopy (FESEM) and furrier transforms infrared (FTIR). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=morphine%20detection" title="morphine detection">morphine detection</a>, <a href="https://publications.waset.org/abstracts/search?q=sensor" title=" sensor"> sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=polypyrrole" title=" polypyrrole"> polypyrrole</a>, <a href="https://publications.waset.org/abstracts/search?q=nanostructure" title=" nanostructure"> nanostructure</a>, <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer" title=" molecularly imprinted polymer"> molecularly imprinted polymer</a> </p> <a href="https://publications.waset.org/abstracts/28071/fabrication-of-a-new-electrochemical-sensor-based-on-new-nanostructured-molecularly-imprinted-polypyrrole-for-selective-and-sensitive-determination-of-morphine" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/28071.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">423</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1540</span> Consequence of Multi-Templating of Closely Related Structural Analogues on a Chitosan-Methacryllic Acid Molecularly Imprinted Polymer Matrix-Thermal and Chromatographic Traits</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=O.Ofoegbu">O.Ofoegbu</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Roongnapa"> S. Roongnapa</a>, <a href="https://publications.waset.org/abstracts/search?q=A.N.%20Eboatu"> A.N. Eboatu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Most polluted environments, most challengingly, aerosol types, contain a cocktail of different toxicants. Multi-templating of matrices have been the recent target by researchers in a bid to solving complex mixed-toxicant challenges using single or common remediation systems. This investigation looks at the effect of such multi-templated system vis-a-vis the synthesis by non-covalent interaction, of a molecularly imprinted polymer architecture using nicotine and its structural analogue Phenylalanine amide individually and, in the blend, (50:50), as template materials in a Chitosan-Methacrylic acid functional monomer matrix. The temperature for polymerization is 60OC and time for polymerization, 12hrs (water bath heating), 4mins for (microwave heating). The characteristic thermal properties of the molecularly imprinted materials are investigated using Simultaneous Thermal Analysis (STA) profiling, while the absorption and separation efficiencies based on the relative retention times and peak areas of templates were studied amongst other properties. Transmission Electron Microscopy (TEM) results obtained, show the creation of heterogeneous nanocavities, regardless, the introduction of Caffeine a close structural analogue presented near-zero perfusion. This confirms the selectivity and specificity of the templated polymers despite its dual-templated nature. The STA results presented the materials as having decomposition temperatures above 250OC and a relative loss in mass of less than19% over a period within 50mins of heating. Consequent to this outcome, multi-templated systems can be fabricated to sequester specifically and selectively targeted toxicants in a mixed toxicant populated system effectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chitosan" title="chitosan">chitosan</a>, <a href="https://publications.waset.org/abstracts/search?q=dual-templated" title=" dual-templated"> dual-templated</a>, <a href="https://publications.waset.org/abstracts/search?q=methacrylic%20acid" title=" methacrylic acid"> methacrylic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=mixed-toxicants" title=" mixed-toxicants"> mixed-toxicants</a>, <a href="https://publications.waset.org/abstracts/search?q=molecularly-imprinted-polymer" title=" molecularly-imprinted-polymer"> molecularly-imprinted-polymer</a> </p> <a href="https://publications.waset.org/abstracts/94989/consequence-of-multi-templating-of-closely-related-structural-analogues-on-a-chitosan-methacryllic-acid-molecularly-imprinted-polymer-matrix-thermal-and-chromatographic-traits" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/94989.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">117</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1539</span> Adsorption and Selective Determination Ametryne in Food Sample Using of Magnetically Separable Molecular Imprinted Polymers </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sajjad%20Hussain">Sajjad Hussain</a>, <a href="https://publications.waset.org/abstracts/search?q=Sabir%20Khan"> Sabir Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Maria%20Del%20Pilar%20Taboada%20Sotomayor"> Maria Del Pilar Taboada Sotomayor</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This work demonstrates the synthesis of magnetic molecularly imprinted polymers (MMIPs) for determination of a selected pesticide (ametryne) using high performance liquid chromatography (HPLC). Computational simulation can assist the choice of the most suitable monomer for the synthesis of polymers. The (MMIPs) were polymerized at the surface of Fe3O4@SiO2 magnetic nanoparticles (MNPs) using 2-vinylpyradine as functional monomer, ethylene-glycol-dimethacrylate (EGDMA) is a cross-linking agent and 2,2-Azobisisobutyronitrile (AIBN) used as radical initiator. Magnetic non-molecularly imprinted polymer (MNIPs) was also prepared under the same conditions without analyte. The MMIPs were characterized by scanning electron microscopy (SEM), Brunauer, Emmett and Teller (BET) and Fourier transform infrared spectroscopy (FTIR). Pseudo first order and pseudo second order model were applied to study kinetics of adsorption and it was found that adsorption process followed the pseudo first order kinetic model. Adsorption equilibrium data was fitted to Freundlich and Langmuir isotherms and the sorption equilibrium process was well described by Langmuir isotherm mode. The selectivity coefficients (α) of MMIPs for ametryne with respect to atrazine, ciprofloxacin and folic acid were 4.28, 12.32, and 14.53 respectively. The spiked recoveries ranged between 91.33 and 106.80% were obtained. The results showed high affinity and selectivity of MMIPs for pesticide ametryne in the food samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer" title="molecularly imprinted polymer">molecularly imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=pesticides" title=" pesticides"> pesticides</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticles" title=" magnetic nanoparticles"> magnetic nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption" title=" adsorption"> adsorption</a> </p> <a href="https://publications.waset.org/abstracts/21370/adsorption-and-selective-determination-ametryne-in-food-sample-using-of-magnetically-separable-molecular-imprinted-polymers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21370.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">486</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1538</span> Perspective for the Creation of Molecular Imprinted Polymers from Coal Waste</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alma%20Khasenovna%20Zhakina">Alma Khasenovna Zhakina</a>, <a href="https://publications.waset.org/abstracts/search?q=Arnt%20Oxana%20Vasilievna"> Arnt Oxana Vasilievna</a>, <a href="https://publications.waset.org/abstracts/search?q=Vasilets%20Evgeny%20Petrovich"> Vasilets Evgeny Petrovich</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this project is to develop methods for obtaining new molecularly imprinted polymers from coal waste to study their structure, structural and morphological features and properties. Recently, the development of molecularly imprinted polymers has become one of the hot topics for researchers. Modern research indicates the broad prospects of rapidly developing molecular imprinting technologies for creating a new generation of sorption materials. The attractiveness of this area of research lies in the fact that the use of imprinted polymers is not limited to scientific research; they are already being introduced in the chemical, pharmaceutical and biotechnological industries, primarily at the stages of purification of the final product. For the use of molecularly imprinted polymers in the development of sorption material, their ability to selectively remove pollutants, including trace concentrations, is of fundamental importance, and the exceptional stability of polymeric materials under harsh conditions makes it possible to simplify the process of water purification as a whole. The scientific and technical effect is associated with the development of technologies for the production of new molecularly imprinted polymers, the establishment of optimal conditions for their production and the creation of effective imprinted sorbents on their basis for wastewater treatment from heavy metals. The social effect is due to the fact that the use of coal waste as a feedstock for the production of imprinted sorbents will make it possible in the future to create new industries with additional jobs and obtain competitive multi-purpose products. The economic and multiplier effect is associated with the low cost of the final product due to the involvement of local coal waste in the production, reduction of transport, customs and other costs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=imprinted%20polymers" title="imprinted polymers">imprinted polymers</a>, <a href="https://publications.waset.org/abstracts/search?q=coal%20waste" title=" coal waste"> coal waste</a>, <a href="https://publications.waset.org/abstracts/search?q=polymerization" title=" polymerization"> polymerization</a>, <a href="https://publications.waset.org/abstracts/search?q=template" title=" template"> template</a>, <a href="https://publications.waset.org/abstracts/search?q=customized%20sorbents" title=" customized sorbents"> customized sorbents</a> </p> <a href="https://publications.waset.org/abstracts/172852/perspective-for-the-creation-of-molecular-imprinted-polymers-from-coal-waste" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/172852.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">66</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1537</span> Use of Magnetically Separable Molecular Imprinted Polymers for Determination of Pesticides in Food Samples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sabir%20Khan">Sabir Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Sajjad%20Hussain"> Sajjad Hussain</a>, <a href="https://publications.waset.org/abstracts/search?q=Ademar%20Wong"> Ademar Wong</a>, <a href="https://publications.waset.org/abstracts/search?q=Maria%20Del%20Pilar%20Taboada%20Sotomayor"> Maria Del Pilar Taboada Sotomayor</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present work aims to develop magnetic molecularly imprinted polymers (MMIPs) for determination of a selected pesticide (ametryne) using high-performance liquid chromatography (HPLC). Computational simulation can assist the choice of the most suitable monomer for the synthesis of polymers. The (MMIPs) were polymerized at the surface of Fe3O4@SiO2 magnetic nanoparticles (MNPs) using 2-vinylpyradine as functional monomer, ethylene-glycol-dimethacrylate (EGDMA) is a cross-linking agent and 2,2-Azobisisobutyronitrile (AIBN) used as radical initiator. Magnetic non-molecularly imprinted polymer (MNIPs) was also prepared under the same conditions without analyte. The MMIPs were characterized by scanning electron microscopy (SEM), Brunauer, Emmett and Teller (BET) and Fourier transform infrared spectroscopy (FTIR). Pseudo first-order and pseudo second order model were applied to study kinetics of adsorption and it was found that adsorption process followed the pseudo-first-order kinetic model. Adsorption equilibrium data was fitted to Freundlich and Langmuir isotherms and the sorption equilibrium process was well described by Langmuir isotherm mode. The selectivity coefficients (α) of MMIPs for ametryne with respect to atrazine, ciprofloxacin and folic acid were 4.28, 12.32 and 14.53 respectively. The spiked recoveries ranged between 91.33 and 106.80% were obtained. The results showed high affinity and selectivity of MMIPs for pesticide ametryne in the food samples. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer" title="molecularly imprinted polymer">molecularly imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=pesticides" title=" pesticides"> pesticides</a>, <a href="https://publications.waset.org/abstracts/search?q=magnetic%20nanoparticles" title=" magnetic nanoparticles"> magnetic nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=adsorption" title=" adsorption"> adsorption</a> </p> <a href="https://publications.waset.org/abstracts/20912/use-of-magnetically-separable-molecular-imprinted-polymers-for-determination-of-pesticides-in-food-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/20912.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">466</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1536</span> A Sensitive Approach on Trace Analysis of Methylparaben in Wastewater and Cosmetic Products Using Molecularly Imprinted Polymer </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Soukaina%20Motia">Soukaina Motia</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadia%20El%20Alami%20El%20Hassani"> Nadia El Alami El Hassani</a>, <a href="https://publications.waset.org/abstracts/search?q=Alassane%20Diouf"> Alassane Diouf</a>, <a href="https://publications.waset.org/abstracts/search?q=Benachir%20Bouchikhi"> Benachir Bouchikhi</a>, <a href="https://publications.waset.org/abstracts/search?q=Nezha%20El%20Bari"> Nezha El Bari </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Parabens are the antimicrobial molecules largely used in cosmetic products as a preservative agent. Among them, the methylparaben (MP) is the most frequently used ingredient in cosmetic preparations. Nevertheless, their potential dangers led to the development of sensible and reliable methods for their determination in environmental samples. Firstly, a sensitive and selective molecular imprinted polymer (MIP) based on screen-printed gold electrode (Au-SPE), assembled on a polymeric layer of carboxylated poly(vinyl-chloride) (PVC-COOH), was developed. After the template removal, the obtained material was able to rebind MP and discriminate it among other interfering species such as glucose, sucrose, and citric acid. The behavior of molecular imprinted sensor was characterized by Cyclic Voltammetry (CV), Differential Pulse Voltammetry (DPV) and Electrochemical Impedance Spectroscopy (EIS) techniques. Then, the biosensor was found to have a linear detection range from 0.1 pg.mL<sup>-1</sup> to 1 ng.mL<sup>-1</sup> and a low limit of detection of 0.12 fg.mL<sup>-1</sup> and 5.18 pg.mL<sup>-1</sup> by DPV and EIS, respectively. For applications, this biosensor was employed to determine MP content in four wastewaters in Meknes city and two cosmetic products (shower gel and shampoo). The operational reproducibility and stability of this biosensor were also studied. Secondly, another MIP biosensor based on tungsten trioxide (WO<sub>3</sub>) functionalized by gold nanoparticles (Au-NPs) assembled on a polymeric layer of PVC-COOH was developed. The main goal was to increase the sensitivity of the biosensor. The developed MIP biosensor was successfully applied for the MP determination in wastewater samples and cosmetic products. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cosmetic%20products" title="cosmetic products">cosmetic products</a>, <a href="https://publications.waset.org/abstracts/search?q=methylparaben" title=" methylparaben"> methylparaben</a>, <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer" title=" molecularly imprinted polymer"> molecularly imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=wastewater" title=" wastewater"> wastewater</a> </p> <a href="https://publications.waset.org/abstracts/65699/a-sensitive-approach-on-trace-analysis-of-methylparaben-in-wastewater-and-cosmetic-products-using-molecularly-imprinted-polymer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65699.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">319</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1535</span> Efficiency of a Molecularly Imprinted Polymer for Selective Removal of Chlorpyrifos from Water Samples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Oya%20A.%20Urucu">Oya A. Urucu</a>, <a href="https://publications.waset.org/abstracts/search?q=Asl%C4%B1%20B.%20%C3%87i%C4%9Fil"> Aslı B. Çiğil</a>, <a href="https://publications.waset.org/abstracts/search?q=Hatice%20Birtane"> Hatice Birtane</a>, <a href="https://publications.waset.org/abstracts/search?q=Ece%20K.%20Yetimo%C4%9Flu"> Ece K. Yetimoğlu</a>, <a href="https://publications.waset.org/abstracts/search?q=Memet%20Vezir%20Kahraman"> Memet Vezir Kahraman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chlorpyrifos is an organophosphorus pesticide which can be found in environmental water samples. The efficiency and reuse of a molecularly imprinted polymer (chlorpyrifos - MIP) were investigated for the selective removal of chlorpyrifos residues. MIP was prepared with UV curing thiol-ene polymerization technology by using multifunctional thiol and ene monomers. The thiol-ene curing reaction is a radical induced process, however unlike other photoinitiated polymerization processes, this polymerization process is a free-radical reaction that proceeds by a step-growth mechanism, involving two main steps; a free-radical addition followed by a chain transfer reaction. It assures a very rapidly formation of a uniform crosslinked network with low shrinkage, reduced oxygen inhibition during curing and excellent adhesion. In this study, thiol-ene based UV-curable polymeric materials were prepared by mixing pentaerythritol tetrakis(3-mercaptopropionate), glyoxal bis diallyl acetal, polyethylene glycol diacrylate (PEGDA) and photoinitiator. Chlorpyrifos was added at a definite ratio to the prepared formulation. Chemical structure and thermal properties were characterized by FTIR and thermogravimetric analysis (TGA), respectively. The pesticide analysis was performed by gas chromatography-mass spectrometry (GC-MS). The influences of some analytical parameters such as pH, sample volume, amounts of analyte concentration were studied for the quantitative recoveries of the analyte. The proposed MIP method was applied to the determination of chlorpyrifos in river and tap water samples. The use of the MIP provided a selective and easy solution for removing chlorpyrifos from the water. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymers" title="molecularly imprinted polymers">molecularly imprinted polymers</a>, <a href="https://publications.waset.org/abstracts/search?q=selective%20removal" title=" selective removal"> selective removal</a>, <a href="https://publications.waset.org/abstracts/search?q=thilol-ene" title=" thilol-ene"> thilol-ene</a>, <a href="https://publications.waset.org/abstracts/search?q=uv-curable%20polymer" title=" uv-curable polymer"> uv-curable polymer</a> </p> <a href="https://publications.waset.org/abstracts/44897/efficiency-of-a-molecularly-imprinted-polymer-for-selective-removal-of-chlorpyrifos-from-water-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44897.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">301</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1534</span> Synthesis of Ion Imprinted Polymer for Removal of Chromium(III) Ion in Environmental Samples </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elham%20Moniri">Elham Moniri</a>, <a href="https://publications.waset.org/abstracts/search?q=Zohre%20Moradi"> Zohre Moradi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, ion imprinted poly urea-formaldehyde was prepared. The morphology imprinted polymer was studied by scanning electron microscopy. Then, the effects of various parameters on Cr(III) sorption such as pH, contact time were investigated. The optimum pH value for sorption of Cr(III) was 6. The sorption capacity of imprinted poly urea-formaldehyde for Cr(III) were 4 mg.g−1. A Cr(III) removal of 97-98% was obtained. The profile of Cr(III) uptake on this sorbent reflects good accessibility of the chelating sites in the imprinted poly urea-formaldehyde. The developed method was utilized for determination of Cr(III) in environmental water samples by flame atomic absorption spectrometry with satisfactory results. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chromium%20ion" title="chromium ion">chromium ion</a>, <a href="https://publications.waset.org/abstracts/search?q=environmental%20sample" title=" environmental sample"> environmental sample</a>, <a href="https://publications.waset.org/abstracts/search?q=elimination" title=" elimination"> elimination</a>, <a href="https://publications.waset.org/abstracts/search?q=imprinted%20poly%20urea-formaldehyde" title=" imprinted poly urea-formaldehyde"> imprinted poly urea-formaldehyde</a>, <a href="https://publications.waset.org/abstracts/search?q=polymeric%20sorbent" title=" polymeric sorbent"> polymeric sorbent</a> </p> <a href="https://publications.waset.org/abstracts/35358/synthesis-of-ion-imprinted-polymer-for-removal-of-chromiumiii-ion-in-environmental-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35358.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">296</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1533</span> Molecularly Imprinted Polymer and Computational Study of (E)-2-Cyano-3-(Dimethylamino)-N-(2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Acrylam-Ide and Its Applications in Industrial Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Asmaa%20M.%20Fahim">Asmaa M. Fahim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this investigation, the (E)-2-cyano-3-(dimethylamino)-N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acrylam-ide (4) which used TAM as a template which interacts with Methacrylic Acid (MAA) monomer, in the presence of CH₃CN as progen. The TAM-MMA complex interactions are dependent on stable hydrogen bonding interaction between the carboxylic acid group of TAM(Template) and the hydroxyl group of MMA(methyl methacrylate) with minimal interference of porogen CH₃CN. The physical computational studies were used to optimize their structures and frequency calculations. The binding energies between TAM with different monomers showed the most stable molar ratio of 1:4, which was confirmed through experimental analysis. The optimized polymers were investigated in industrial applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecular%20imprinted%20polymer" title="molecular imprinted polymer">molecular imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=computational%20studies" title=" computational studies"> computational studies</a>, <a href="https://publications.waset.org/abstracts/search?q=SEM" title=" SEM"> SEM</a>, <a href="https://publications.waset.org/abstracts/search?q=spectral%20analysis" title=" spectral analysis"> spectral analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=industrial%20applications" title=" industrial applications"> industrial applications</a> </p> <a href="https://publications.waset.org/abstracts/115228/molecularly-imprinted-polymer-and-computational-study-of-e-2-cyano-3-dimethylamino-n-24-dioxo-1234-tetrahydropyrimidin-5-ylacrylam-ide-and-its-applications-in-industrial-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/115228.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">161</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1532</span> Extraction and Quantification of Triclosan in Wastewater Samples Using Molecularly Imprinted Membrane Adsorbent</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Siyabonga%20Aubrey%20Mhlongo">Siyabonga Aubrey Mhlongo</a>, <a href="https://publications.waset.org/abstracts/search?q=Linda%20Lunga%20Sibali"> Linda Lunga Sibali</a>, <a href="https://publications.waset.org/abstracts/search?q=Phumlane%20Selby%20Mdluli"> Phumlane Selby Mdluli</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20Papoh%20Ndibewu"> Peter Papoh Ndibewu</a>, <a href="https://publications.waset.org/abstracts/search?q=Kholofelo%20Clifford%20Malematja"> Kholofelo Clifford Malematja</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper reports on the successful extraction and quantification of an antibacterial and antifungal agent present in some consumer products (Triclosan: C₁₂H₇Cl₃O₂)generally found in wastewater or effluents using molecularly imprinted membrane adsorbent (MIMs) followed by quantification and removal on a high-performance liquid chromatography (HPLC). Triclosan is an antibacterial and antifungal agent present in some consumer products like toothpaste, soaps, detergents, toys, and surgical cleaning treatments. The MIMs was fabricated usingpolyvinylidene fluoride (PVDF) polymer with selective micro composite particles known as molecularly imprinted polymers (MIPs)via a phase inversion by immersion precipitation technique. This resulted in an improved hydrophilicity and mechanical behaviour of the membranes. Wastewater samples were collected from the Umbogintwini Industrial Complex (UIC) (south coast of Durban, KwaZulu-Natal in South Africa). central UIC effluent treatment plant and pre-treated before analysis. Experimental parameters such as sample size, contact time, stirring speed were optimised. The resultant MIMs had an adsorption efficiency of 97% of TCS with reference to NIMs and bare membrane, which had 92%, 88%, respectively. The analytical method utilized in this review had limits of detection (LoD) and limits of quantification (LoQ) of 0.22, 0.71µgL-1 in wastewater effluent, respectively. The percentage recovery for the effluent samples was 68%. The detection of TCS was monitored for 10 consecutive days, where optimum TCS traces detected in the treated wastewater was 55.0μg/L inday 9 of the monitored days, while the lowest detected was 6.0μg/L. As the concentrations of analytefound in effluent water samples were not so diverse, this study suggested that MIMs could be the best potential adsorbent for the development and continuous progress in membrane technologyand environmental sciences, lending its capability to desalination. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20membrane" title="molecularly imprinted membrane">molecularly imprinted membrane</a>, <a href="https://publications.waset.org/abstracts/search?q=triclosan" title=" triclosan"> triclosan</a>, <a href="https://publications.waset.org/abstracts/search?q=phase%20inversion" title=" phase inversion"> phase inversion</a>, <a href="https://publications.waset.org/abstracts/search?q=wastewater" title=" wastewater"> wastewater</a> </p> <a href="https://publications.waset.org/abstracts/151834/extraction-and-quantification-of-triclosan-in-wastewater-samples-using-molecularly-imprinted-membrane-adsorbent" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151834.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">123</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1531</span> Synthesis of Highly Sensitive Molecular Imprinted Sensor for Selective Determination of Doxycycline in Honey Samples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nadia%20El%20Alami%20El%20Hassani">Nadia El Alami El Hassani</a>, <a href="https://publications.waset.org/abstracts/search?q=Soukaina%20Motia"> Soukaina Motia</a>, <a href="https://publications.waset.org/abstracts/search?q=Benachir%20Bouchikhi"> Benachir Bouchikhi</a>, <a href="https://publications.waset.org/abstracts/search?q=Nezha%20El%20Bari"> Nezha El Bari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Doxycycline (DXy) is a cycline antibiotic, most frequently prescribed to treat bacterial infections in veterinary medicine. However, its broad antimicrobial activity and low cost, lead to an intensive use, which can seriously affect human health. Therefore, its spread in the food products has to be monitored. The scope of this work was to synthetize a sensitive and very selective molecularly imprinted polymer (MIP) for DXy detection in honey samples. Firstly, the synthesis of this biosensor was performed by casting a layer of carboxylate polyvinyl chloride (PVC-COOH) on the working surface of a gold screen-printed electrode (Au-SPE) in order to bind covalently the analyte under mild conditions. Secondly, DXy as a template molecule was bounded to the activated carboxylic groups, and the formation of MIP was performed by a biocompatible polymer by the mean of polyacrylamide matrix. Then, DXy was detected by measurements of differential pulse voltammetry (DPV). A non-imprinted polymer (NIP) prepared in the same conditions and without the use of template molecule was also performed. We have noticed that the elaborated biosensor exhibits a high sensitivity and a linear behavior between the regenerated current and the logarithmic concentrations of DXy from 0.1 pg.mL<sup>−1</sup> to 1000 pg.mL<sup>−1</sup>. This technic was successfully applied to determine DXy residues in honey samples with a limit of detection (LOD) of 0.1 pg.mL<sup>−1</sup> and an excellent selectivity when compared to the results of oxytetracycline (OXy) as analogous interfering compound. The proposed method is cheap, sensitive, selective, simple, and is applied successfully to detect DXy in honey with the recoveries of 87% and 95%. Considering these advantages, this system provides a further perspective for food quality control in industrial fields. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=doxycycline" title="doxycycline">doxycycline</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical%20sensor" title=" electrochemical sensor"> electrochemical sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=food%20control" title=" food control"> food control</a>, <a href="https://publications.waset.org/abstracts/search?q=gold%20nanoparticles" title=" gold nanoparticles"> gold nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=honey" title=" honey"> honey</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20imprinted%20polymer" title=" molecular imprinted polymer"> molecular imprinted polymer</a> </p> <a href="https://publications.waset.org/abstracts/65683/synthesis-of-highly-sensitive-molecular-imprinted-sensor-for-selective-determination-of-doxycycline-in-honey-samples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/65683.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">316</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1530</span> Generating a Multiplex Sensing Platform for the Accurate Diagnosis of Sepsis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20Demertzis">N. Demertzis</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20L.%20Bowen"> J. L. Bowen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sepsis is a complex and rapidly evolving condition, resulting from uncontrolled prolonged activation of host immune system due to pathogenic insult. The aim of this study is the development of a multiplex electrochemical sensing platform, capable of detecting both pathogen associated and host immune markers to enable the rapid and definitive diagnosis of sepsis. A combination of aptamers and molecular imprinting approaches have been employed to generate sensing systems for lipopolysaccharide (LPS), c-reactive protein (CRP) and procalcitonin (PCT). Gold working electrodes were mechanically polished and electrochemically cleaned with 0.1 M sulphuric acid using cyclic voltammetry (CV). Following activation, a self-assembled monolayer (SAM) was generated, by incubating the electrodes with a thiolated anti-LPS aptamer / dithiodibutiric acid (DTBA) mixture (1:20). 3-aminophenylboronic acid (3-APBA) in combination with the anti-LPS aptamer was used for the development of the hybrid molecularly imprinted sensor (apta-MIP). Aptasensors, targeting PCT and CRP were also fabricated, following the same approach as in the case of LPS, with mercaptohexanol (MCH) replacing DTBA. In the case of the CRP aptasensor, the SAM was formed following incubation of a 1:1 aptamer: MCH mixture. However, in the case of PCT, the SAM was formed with the aptamer itself, with subsequent backfilling with 1 μM MCH. The binding performance of all systems has been evaluated using electrochemical impedance spectroscopy. The apta-MIP’s polymer thickness is controlled by varying the number of electropolymerisation cycles. In the ideal number of polymerisation cycles, the polymer must cover the electrode surface and create a binding pocket around LPS and its aptamer binding site. Less polymerisation cycles will create a hybrid system which resembles an aptasensor, while more cycles will be able to cover the complex and demonstrate a bulk polymer-like behaviour. Both aptasensor and apta-MIP were challenged with LPS and compared to conventional imprinted (absence of aptamer from the binding site, polymer formed in presence of LPS) and non-imprinted polymers (NIPS, absence of LPS whilst hybrid polymer is formed). A stable LPS aptasensor, capable of detecting down to 5 pg/ml of LPS was generated. The apparent Kd of the system was estimated at 17 pM, with a Bmax of approximately 50 pM. The aptasensor demonstrated high specificity to LPS. The apta-MIP demonstrated superior recognition properties with a limit of detection of 1 fg/ml and a Bmax of 100 pg/ml. The CRP and PCT aptasensors were both able to detect down to 5 pg/ml. Whilst full binding performance is currently being evaluated, there is none of the sensors demonstrate cross-reactivity towards LPS, CRP or PCT. In conclusion, stable aptasensors capable of detecting LPS, PCT and CRP at low concentrations have been generated. The realisation of a multiplex panel such as described herein, will effectively contribute to the rapid, personalised diagnosis of sepsis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aptamer" title="aptamer">aptamer</a>, <a href="https://publications.waset.org/abstracts/search?q=electrochemical%20impedance%20spectroscopy" title=" electrochemical impedance spectroscopy"> electrochemical impedance spectroscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymers" title=" molecularly imprinted polymers"> molecularly imprinted polymers</a>, <a href="https://publications.waset.org/abstracts/search?q=sepsis" title=" sepsis"> sepsis</a> </p> <a href="https://publications.waset.org/abstracts/99827/generating-a-multiplex-sensing-platform-for-the-accurate-diagnosis-of-sepsis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99827.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">125</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1529</span> Determination of Cyclic Citrullinated Peptide Antibodies on Quartz Crystal Microbalance Based Nanosensors</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Y.%20Saylan">Y. Saylan</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Y%C4%B1lmaz"> F. Yılmaz</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Denizli"> A. Denizli</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Rheumatoid arthritis (RA) which is the most common autoimmune disorder of the body's own immune system attacking healthy cells. RA has both articular and systemic effects.Until now romatiod factor (RF) assay is used the most commonly diagnosed RA but it is not specific. Anti-cyclic citrullinated peptide (anti-CCP) antibodies are IgG autoantibodies which recognize citrullinated peptides and offer improved specificity in early diagnosis of RA compared to RF. Anti-CCP antibodies have specificity for the diagnosis of RA from 91 to 98% and the sensitivity rate of 41-68%. Molecularly imprinted polymers (MIP) are materials that are easy to prepare, less expensive, stable have a talent for molecular recognition and also can be manufactured in large quantities with good reproducibility. Molecular recognition-based adsorption techniques have received much attention in several fields because of their high selectivity for target molecules. Quartz crystal microbalance (QCM) is an effective, simple, inexpensive approach mass changes that can be converted into an electrical signal. The applications for specific determination of chemical substances or biomolecules, crystal electrodes, cover by the thin films for bind or adsorption of molecules. In this study, we have focused our attention on combining of molecular imprinting into nanofilms and QCM nanosensor approaches and producing QCM nanosensor for anti-CCP, chosen as a model protein, using anti-CCP imprinted nanofilms. For this aim, anti-CCP imprinted QCM nanosensor was characterized by Fourier transform infrared spectroscopy, atomic force microscopy, contact angle measurements and ellipsometry. The non-imprinted nanosensor was also prepared to evaluate the selectivity of the imprinted nanosensor. Anti-CCP imprinted QCM nanosensor was tested for real-time detection of anti-CCP from aqueous solution. The kinetic and affinity studies were determined by using anti-CCP solutions with different concentrations. The responses related with mass shifts (Δm) and frequency shifts (Δf) were used to evaluate adsorption properties and to calculate binding (Ka) and dissociation (Kd) constants. To show the selectivity of the anti-CCP imprinted QCM nanosensor, competitive adsorption of anti-CCP and IgM was investigated.The results indicate that anti-CCP imprinted QCM nanosensor has a higher adsorption capabilities for anti-CCP than for IgM, due to selective cavities in the polymer structure. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anti-CCP" title="anti-CCP">anti-CCP</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20imprinting" title=" molecular imprinting"> molecular imprinting</a>, <a href="https://publications.waset.org/abstracts/search?q=nanosensor" title=" nanosensor"> nanosensor</a>, <a href="https://publications.waset.org/abstracts/search?q=rheumatoid%20arthritis" title=" rheumatoid arthritis"> rheumatoid arthritis</a>, <a href="https://publications.waset.org/abstracts/search?q=QCM" title=" QCM"> QCM</a> </p> <a href="https://publications.waset.org/abstracts/23259/determination-of-cyclic-citrullinated-peptide-antibodies-on-quartz-crystal-microbalance-based-nanosensors" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/23259.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">363</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1528</span> The Fabrication of Stress Sensing Based on Artificial Antibodies to Cortisol by Molecular Imprinted Polymer </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Supannika%20Klangphukhiew">Supannika Klangphukhiew</a>, <a href="https://publications.waset.org/abstracts/search?q=Roongnapa%20Srichana"> Roongnapa Srichana</a>, <a href="https://publications.waset.org/abstracts/search?q=Rina%20Patramanon"> Rina Patramanon</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cortisol has been used as a well-known commercial stress biomarker. A homeostasis response to psychological stress is indicated by an increased level of cortisol produced in hypothalamus-pituitary-adrenal (HPA) axis. Chronic psychological stress contributing to the high level of cortisol relates to several health problems. In this study, the cortisol biosensor was fabricated that mimicked the natural receptors. The artificial antibodies were prepared using molecular imprinted polymer technique that can imitate the performance of natural anti-cortisol antibody with high stability. Cortisol-molecular imprinted polymer (cortisol-MIP) was obtained using the multi-step swelling and polymerization protocol with cortisol as a target molecule combining methacrylic acid:acrylamide (2:1) with bisacryloyl-1,2-dihydroxy-1,2-ethylenediamine and ethylenedioxy-N-methylamphetamine as cross-linkers. Cortisol-MIP was integrated to the sensor. It was coated on the disposable screen-printed carbon electrode (SPCE) for portable electrochemical analysis. The physical properties of Cortisol-MIP were characterized by means of electron microscope techniques. The binding characteristics were evaluated via covalent patterns changing in FTIR spectra which were related to voltammetry response. The performance of cortisol-MIP modified SPCE was investigated in terms of detection range, high selectivity with a detection limit of 1.28 ng/ml. The disposable cortisol biosensor represented an application of MIP technique to recognize steroids according to their structures with feasibility and cost-effectiveness that can be developed to use in point-of-care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=stress%20biomarker" title="stress biomarker">stress biomarker</a>, <a href="https://publications.waset.org/abstracts/search?q=cortisol" title=" cortisol"> cortisol</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20imprinted%20polymer" title=" molecular imprinted polymer"> molecular imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=screen-printed%20carbon%20electrode" title=" screen-printed carbon electrode"> screen-printed carbon electrode</a> </p> <a href="https://publications.waset.org/abstracts/63750/the-fabrication-of-stress-sensing-based-on-artificial-antibodies-to-cortisol-by-molecular-imprinted-polymer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/63750.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">273</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1527</span> Chromatographic Preparation and Performance on Zinc Ion Imprinted Monolithic Column and Its Adsorption Property</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=X.%20Han">X. Han</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Duan"> S. Duan</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Liu"> C. Liu</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Zhou"> C. Zhou</a>, <a href="https://publications.waset.org/abstracts/search?q=W.%20Zhu"> W. Zhu</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Kong"> L. Kong</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The ionic imprinting technique refers to the three-dimensional rigid structure with the fixed pore sizes, which was formed by the binding interactions of ions and functional monomers and used ions as the template, it has a high level of recognition to the ionic template. The preparation of monolithic column by the in-situ polymerization need to put the compound of template, functional monomers, cross-linking agent and initiating agent into the solution, dissolve it and inject to the column tube, and then the compound will have a polymerization reaction at a certain temperature, after the synthetic reaction, we washed out the unread template and solution. The monolithic columns are easy to prepare, low consumption and cost-effective with fast mass transfer, besides, they have many chemical functions. But the monolithic columns have some problems in the practical application, such as low-efficiency, quantitative analysis cannot be performed accurately because of the peak shape is wide and has tailing phenomena; the choice of polymerization systems is limited and the lack of theoretical foundations. Thus the optimization of components and preparation methods is an important research direction. During the preparation of ionic imprinted monolithic columns, pore-forming agent can make the polymer generate the porous structure, which can influence the physical properties of polymer, what’ s more, it can directly decide the stability and selectivity of polymerization reaction. The compounds generated in the pre-polymerization reaction could directly decide the identification and screening capabilities of imprinted polymer; thus the choice of pore-forming agent is quite critical in the preparation of imprinted monolithic columns. This article mainly focuses on the research that when using different pore-forming agents, the impact of zinc ion imprinted monolithic column on the enrichment performance of zinc ion. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=high%20performance%20liquid%20chromatography%20%28HPLC%29" title="high performance liquid chromatography (HPLC)">high performance liquid chromatography (HPLC)</a>, <a href="https://publications.waset.org/abstracts/search?q=ionic%20imprinting" title=" ionic imprinting"> ionic imprinting</a>, <a href="https://publications.waset.org/abstracts/search?q=monolithic%20column" title=" monolithic column"> monolithic column</a>, <a href="https://publications.waset.org/abstracts/search?q=pore-forming%20agent" title=" pore-forming agent"> pore-forming agent</a> </p> <a href="https://publications.waset.org/abstracts/82128/chromatographic-preparation-and-performance-on-zinc-ion-imprinted-monolithic-column-and-its-adsorption-property" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/82128.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">214</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1526</span> A Multi-Templated Fe-Ni-Cu Ion Imprinted Polymer for the Selective and Simultaneous Removal of Toxic Metallic Ions from Wastewater</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Morlu%20Stevens">Morlu Stevens</a>, <a href="https://publications.waset.org/abstracts/search?q=Bareki%20Batlokwa"> Bareki Batlokwa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The use of treated wastewater is widely employed to compensate for the scarcity of safe and uncontaminated freshwater. However, the existence of toxic heavy metal ions in the wastewater pose a health hazard to animals and the environment, hence, the importance for an effective technique to tackle the challenge. A multi-templated ion imprinted sorbent (Fe,Ni,Cu-IIP) for the simultaneous removal of heavy metal ions from waste water was synthesised employing molecular imprinting technology (MIT) via thermal free radical bulk polymerization technique. Methacrylic acid (MAA) was employed as the functional monomer, and ethylene glycol dimethylacrylate (EGDMA) as cross-linking agent, azobisisobutyronitrile (AIBN) as the initiator, Fe, Ni, Cu ions as template ions, and 1,10-phenanthroline as the complexing agent. The template ions were exhaustively washed off the synthesized polymer by solvent extraction in several washing steps, while periodically increasing solvent (HCl) concentration from 1.0 M to 10.0 M. The physical and chemical properties of the sorbents were investigated using Fourier Transform Infrared Spectroscopy (FT-IR), X-ray Diffraction (XRD) and Atomic Force Microscopy (AFM) were employed. Optimization of operational parameters such as time, pH and sorbent dosage to evaluate the effectiveness of sorbents were investigated and found to be 15 min, 7.5 and 666.7 mg/L respectively. Selectivity of ion-imprinted polymers and competitive sorption studies between the template and similar ions were carried out and showed good selectivity towards the targeted metal ion by removing 90% - 98% of the templated ions as compared to 58% - 62% of similar ions. The sorbents were further applied for the selective removal of Fe, Ni and Cu from real wastewater samples and recoveries of 92.14 ± 0.16% - 106.09 ± 0.17% and linearities of R2 = 0.9993 - R2 = 0.9997 were achieved. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ion%20imprinting" title="ion imprinting">ion imprinting</a>, <a href="https://publications.waset.org/abstracts/search?q=ion%20imprinted%20polymers" title=" ion imprinted polymers"> ion imprinted polymers</a>, <a href="https://publications.waset.org/abstracts/search?q=heavy%20metals" title=" heavy metals"> heavy metals</a>, <a href="https://publications.waset.org/abstracts/search?q=wastewater" title=" wastewater"> wastewater</a> </p> <a href="https://publications.waset.org/abstracts/58114/a-multi-templated-fe-ni-cu-ion-imprinted-polymer-for-the-selective-and-simultaneous-removal-of-toxic-metallic-ions-from-wastewater" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58114.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">314</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1525</span> Molecularly Imprinted Nanoparticles (MIP NPs) as Non-Animal Antibodies Substitutes for Detection of Viruses</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alessandro%20Poma">Alessandro Poma</a>, <a href="https://publications.waset.org/abstracts/search?q=Kal%20Karim"> Kal Karim</a>, <a href="https://publications.waset.org/abstracts/search?q=Sergey%20Piletsky"> Sergey Piletsky</a>, <a href="https://publications.waset.org/abstracts/search?q=Giuseppe%20Battaglia"> Giuseppe Battaglia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The recent increasing emergency threat to public health of infectious influenza diseases has prompted interest in the detection of avian influenza virus (AIV) H5N1 in humans as well as animals. A variety of technologies for diagnosing AIV infection have been developed. However, various disadvantages (costs, lengthy analyses, and need for high-containment facilities) make these methods less than ideal in their practical application. Molecularly Imprinted Polymeric Nanoparticles (MIP NPs) are suitable to overcome these limitations by having high affinity, selectivity, versatility, scalability and cost-effectiveness with the versatility of post-modification (labeling – fluorescent, magnetic, optical) opening the way to the potential introduction of improved diagnostic tests capable of providing rapid differential diagnosis. Here we present our first results in the production and testing of MIP NPs for the detection of AIV H5N1. Recent developments in the solid-phase synthesis of MIP NPs mean that for the first time a reliable supply of ‘soluble’ synthetic antibodies can be made available for testing as potential biological or diagnostic active molecules. The MIP NPs have the potential to detect viruses that are widely circulating in farm animals and indeed humans. Early and accurate identification of the infectious agent will expedite appropriate control measures. Thus, diagnosis at an early stage of infection of a herd or flock or individual maximizes the efficiency with which containment, prevention and possibly treatment strategies can be implemented. More importantly, substantiating the practicability’s of these novel reagents should lead to an initial reduction and eventually to a potential total replacement of animals, both large and small, to raise such specific serological materials. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=influenza%20virus" title="influenza virus">influenza virus</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20imprinting" title=" molecular imprinting"> molecular imprinting</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles"> nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=polymers" title=" polymers"> polymers</a> </p> <a href="https://publications.waset.org/abstracts/29566/molecularly-imprinted-nanoparticles-mip-nps-as-non-animal-antibodies-substitutes-for-detection-of-viruses" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/29566.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">362</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1524</span> Improving Binding Selectivity in Molecularly Imprinted Polymers from Templates of Higher Biomolecular Weight: An Application in Cancer Targeting and Drug Delivery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ben%20Otange">Ben Otange</a>, <a href="https://publications.waset.org/abstracts/search?q=Wolfgang%20Parak"> Wolfgang Parak</a>, <a href="https://publications.waset.org/abstracts/search?q=Florian%20Schulz"> Florian Schulz</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Alexander%20Rubhausen"> Michael Alexander Rubhausen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The feasibility of extending the usage of molecular imprinting technique in complex biomolecules is demonstrated in this research. This technique is promising in diverse applications in areas such as drug delivery, diagnosis of diseases, catalysts, and impurities detection as well as treatment of various complications. While molecularly imprinted polymers MIP remain robust in the synthesis of molecules with remarkable binding sites that have high affinities to specific molecules of interest, extending the usage to complex biomolecules remains futile. This work reports on the successful synthesis of MIP from complex proteins: BSA, Transferrin, and MUC1. We show in this research that despite the heterogeneous binding sites and higher conformational flexibility of the chosen proteins, relying on their respective epitopes and motifs rather than the whole template produces highly sensitive and selective MIPs for specific molecular binding. Introduction: Proteins are vital in most biological processes, ranging from cell structure and structural integrity to complex functions such as transport and immunity in biological systems. Unlike other imprinting templates, proteins have heterogeneous binding sites in their complex long-chain structure, which makes their imprinting to be marred by challenges. In addressing this challenge, our attention is inclined toward the targeted delivery, which will use molecular imprinting on the particle surface so that these particles may recognize overexpressed proteins on the target cells. Our goal is thus to make surfaces of nanoparticles that specifically bind to the target cells. Results and Discussions: Using epitopes of BSA and MUC1 proteins and motifs with conserved receptors of transferrin as the respective templates for MIPs, significant improvement in the MIP sensitivity to the binding of complex protein templates was noted. Through the Fluorescence Correlation Spectroscopy FCS measurements on the size of protein corona after incubation of the synthesized nanoparticles with proteins, we noted a high affinity of MIPs to the binding of their respective complex proteins. In addition, quantitative analysis of hard corona using SDS-PAGE showed that only a specific protein was strongly bound on the respective MIPs when incubated with similar concentrations of the protein mixture. Conclusion: Our findings have shown that the merits of MIPs can be extended to complex molecules of higher biomolecular mass. As such, the unique merits of the technique, including high sensitivity and selectivity, relative ease of synthesis, production of materials with higher physical robustness, and higher stability, can be extended to more templates that were previously not suitable candidates despite their abundance and usage within the body. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymers" title="molecularly imprinted polymers">molecularly imprinted polymers</a>, <a href="https://publications.waset.org/abstracts/search?q=specific%20binding" title=" specific binding"> specific binding</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20delivery" title=" drug delivery"> drug delivery</a>, <a href="https://publications.waset.org/abstracts/search?q=high%20biomolecular%20mass-templates" title=" high biomolecular mass-templates"> high biomolecular mass-templates</a> </p> <a href="https://publications.waset.org/abstracts/183240/improving-binding-selectivity-in-molecularly-imprinted-polymers-from-templates-of-higher-biomolecular-weight-an-application-in-cancer-targeting-and-drug-delivery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183240.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">55</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1523</span> Development of Milky Products Leavend by Kefir Grains with Reduced Lactose and Flavored with Tropical Fruit</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20L.%20Balieiro">A. L. Balieiro</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20S.%20Silveira"> D. S. Silveira</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20A.%20Santos"> R. A. Santos</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20S.%20Freitas"> L. S. Freitas</a>, <a href="https://publications.waset.org/abstracts/search?q=O.%20L.%20S.%20De%20Alsina"> O. L. S. De Alsina</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20S.%20Lima"> A. S. Lima</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20M.%20F.%20Soares"> C. M. F. Soares </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The state of Sergipe has been emerging in milk production, mainly in the dairy basin located in the northeast of the state of the Brazil. However, this area concentrates the production of dairy, developing diverse products with higher aggregated value and scent and regional flavours. With this goal the present wok allows the development of dairy drinks with reduced lactose index, using kefir grains flavored with mangaba pulp. Initially, the removal of milk lactose was evaluated in adsorption columns completed with silica particles obtained by molecular impression technique, using sol ? gel method with the presence and absence of lactose biomolecule, molecular imprinted polymer (PIM) or pure matrix (MP), respectively. Then kefir grains were used for the development of dairy drinks flavored with regional fruits (mangaba). The products were analyzed sensorially, evaluated the probiotic potential and the removal of the lactose. Among the products obtained, the one that present best result in the sensorially was to the drink with removal PIM flavored of mangaba, for which around 60% of the testers indicated that would buy the new product. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=molecular%20imprinted%20polymer" title="molecular imprinted polymer">molecular imprinted polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=milk" title=" milk"> milk</a>, <a href="https://publications.waset.org/abstracts/search?q=lactose" title=" lactose"> lactose</a>, <a href="https://publications.waset.org/abstracts/search?q=kefir" title=" kefir"> kefir</a> </p> <a href="https://publications.waset.org/abstracts/3617/development-of-milky-products-leavend-by-kefir-grains-with-reduced-lactose-and-flavored-with-tropical-fruit" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3617.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">286</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1522</span> Fabrication of Highly Stable Low-Density Self-Assembled Monolayers by Thiolyne Click Reaction</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leila%20Safazadeh">Leila Safazadeh</a>, <a href="https://publications.waset.org/abstracts/search?q=Brad%20Berron"> Brad Berron</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Self-assembled monolayers have tremendous impact in interfacial science, due to the unique opportunity they offer to tailor surface properties. Low-density self-assembled monolayers are an emerging class of monolayers where the environment-interfacing portion of the adsorbate has a greater level of conformational freedom when compared to traditional monolayer chemistries. This greater range of motion and increased spacing between surface-bound molecules offers new opportunities in tailoring adsorption phenomena in sensing systems. In particular, we expect low-density surfaces to offer a unique opportunity to intercalate surface bound ligands into the secondary structure of protiens and other macromolecules. Additionally, as many conventional sensing surfaces are built upon gold surfaces (SPR or QCM), these surfaces must be compatible with gold substrates. Here, we present the first stable method of generating low-density self assembled monolayer surfaces on gold for the analysis of their interactions with protein targets. Our approach is based on the 2:1 addition of thiol-yne chemistry to develop new classes of y-shaped adsorbates on gold, where the environment-interfacing group is spaced laterally from neighboring chemical groups. This technique involves an initial deposition of a crystalline monolayer of 1,10 decanedithiol on the gold substrate, followed by grafting of a low-packed monolayer on through a photoinitiated thiol-yne reaction in presence of light. Orthogonality of the thiol-yne chemistry (commonly referred to as a click chemistry) allows for preparation of low-density monolayers with variety of functional groups. To date, carboxyl, amine, alcohol, and alkyl terminated monolayers have been prepared using this core technology. Results from surface characterization techniques such as FTIR, contact angle goniometry and electrochemical impedance spectroscopy confirm the proposed low chain-chain interactions of the environment interfacing groups. Reductive desorption measurements suggest a higher stability for the click-LDMs compared to traditional SAMs, along with the equivalent packing density at the substrate interface, which confirms the proposed stability of the monolayer-gold interface. In addition, contact angle measurements change in the presence of an applied potential, supporting our description of a surface structure which allows the alkyl chains to freely orient themselves in response to different environments. We are studying the differences in protein adsorption phenomena between well packed and our loosely packed surfaces, and we expect this data will be ready to present at the GRC meeting. This work aims to contribute biotechnology science in the following manner: Molecularly imprinted polymers are a promising recognition mode with several advantages over natural antibodies in the recognition of small molecules. However, because of their bulk polymer structure, they are poorly suited for the rapid diffusion desired for recognition of proteins and other macromolecules. Molecularly imprinted monolayers are an emerging class of materials where the surface is imprinted, and there is not a bulk material to impede mass transfer. Further, the short distance between the binding site and the signal transduction material improves many modes of detection. My dissertation project is to develop a new chemistry for protein-imprinted self-assembled monolayers on gold, for incorporation into SPR sensors. Our unique contribution is the spatial imprinting of not only physical cues (seen in current imprinted monolayer techniques), but to also incorporate complementary chemical cues. This is accomplished through a photo-click grafting of preassembled ligands around a protein template. This conference is important for my development as a graduate student to broaden my appreciation of the sensor development beyond surface chemistry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=low-density%20self-assembled%20monolayers" title="low-density self-assembled monolayers">low-density self-assembled monolayers</a>, <a href="https://publications.waset.org/abstracts/search?q=thiol-yne%20click%20reaction" title=" thiol-yne click reaction"> thiol-yne click reaction</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20imprinting" title=" molecular imprinting"> molecular imprinting</a> </p> <a href="https://publications.waset.org/abstracts/11355/fabrication-of-highly-stable-low-density-self-assembled-monolayers-by-thiolyne-click-reaction" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/11355.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">226</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1521</span> Comparison of a Capacitive Sensor Functionalized with Natural or Synthetic Receptors Selective towards Benzo(a)Pyrene</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Natalia%20V.%20Beloglazova">Natalia V. Beloglazova</a>, <a href="https://publications.waset.org/abstracts/search?q=Pieterjan%20Lenain"> Pieterjan Lenain</a>, <a href="https://publications.waset.org/abstracts/search?q=Martin%20Hedstrom"> Martin Hedstrom</a>, <a href="https://publications.waset.org/abstracts/search?q=Dietmar%20Knopp"> Dietmar Knopp</a>, <a href="https://publications.waset.org/abstracts/search?q=Sarah%20De%20Saeger"> Sarah De Saeger</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years polycyclic aromatic hydrocarbons (PAHs), which represent a hazard to humans and entire ecosystem, have been receiving an increased interest due to their mutagenic, carcinogenic and endocrine disrupting properties. They are formed in all incomplete combustion processes of organic matter and, as a consequence, ubiquitous in the environment. Benzo(a)pyrene (BaP) is on the priority list published by the Environmental Agency (US EPA) as the first PAH to be identified as a carcinogen and has often been used as a marker for PAHs contamination in general. It can be found in different types of water samples, therefore, the European Commission set up a limit value of 10 ng L–1 (10 ppt) for BAP in water intended for human consumption. Generally, different chromatographic techniques are used for PAHs determination, but these assays require pre-concentration of analyte, create large amounts of solvent waste, and are relatively time consuming and difficult to perform on-site. An alternative robust, stand-alone, and preferably cheap solution is needed. For example, a sensing unit which can be submerged in a river to monitor and continuously sample BaP. An affinity sensor based on capacitive transduction was developed. Natural antibodies or their synthetic analogues can be used as ligands. Ideally the sensor should operate independently over a longer period of time, e.g. several weeks or months, therefore the use of molecularly imprinted polymers (MIPs) was discussed. MIPs are synthetic antibodies which are selective for a chosen target molecule. Their robustness allows application in environments for which biological recognition elements are unsuitable or denature. They can be reused multiple times, which is essential to meet the stand-alone requirement. BaP is a highly lipophilic compound and does not contain any functional groups in its structure, thus excluding non-covalent imprinting methods based on ionic interactions. Instead, the MIPs syntheses were based on non-covalent hydrophobic and π-π interactions. Different polymerization strategies were compared and the best results were demonstrated by the MIPs produced using electropolymerization. 4-vinylpyridin (VP) and divinylbenzene (DVB) were used as monomer and cross-linker in the polymerization reaction. The selectivity and recovery of the MIP were compared to a non-imprinted polymer (NIP). Electrodes were functionalized with natural receptor (monoclonal anti-BaP antibody) and with MIPs selective towards BaP. Different sets of electrodes were evaluated and their properties such as sensitivity, selectivity and linear range were determined and compared. It was found that both receptor can reach the cut-off level comparable to the established ML, and despite the fact that the antibody showed the better cross-reactivity and affinity, MIPs were more convenient receptor due to their ability to regenerate and stability in river till 7 days. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antibody" title="antibody">antibody</a>, <a href="https://publications.waset.org/abstracts/search?q=benzo%28a%29pyrene" title=" benzo(a)pyrene"> benzo(a)pyrene</a>, <a href="https://publications.waset.org/abstracts/search?q=capacitive%20sensor" title=" capacitive sensor"> capacitive sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=MIPs" title=" MIPs"> MIPs</a>, <a href="https://publications.waset.org/abstracts/search?q=river%20water" title=" river water"> river water</a> </p> <a href="https://publications.waset.org/abstracts/43965/comparison-of-a-capacitive-sensor-functionalized-with-natural-or-synthetic-receptors-selective-towards-benzoapyrene" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43965.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">303</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1520</span> Studying the Bond Strength of Geo-Polymer Concrete</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rama%20Seshu%20Doguparti">Rama Seshu Doguparti</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper presents the experimental investigation on the bond behavior of geo polymer concrete. The bond behavior of geo polymer concrete cubes of grade M35 reinforced with 16 mm TMT rod is analyzed. The results indicate that the bond performance of reinforced geo polymer concrete is good and thus proves its application for construction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=geo-polymer" title="geo-polymer">geo-polymer</a>, <a href="https://publications.waset.org/abstracts/search?q=concrete" title=" concrete"> concrete</a>, <a href="https://publications.waset.org/abstracts/search?q=bond%20strength" title=" bond strength"> bond strength</a>, <a href="https://publications.waset.org/abstracts/search?q=behaviour" title=" behaviour"> behaviour</a> </p> <a href="https://publications.waset.org/abstracts/19114/studying-the-bond-strength-of-geo-polymer-concrete" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19114.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">508</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1519</span> Advantages of Matrix Solid Phase Dispersive (MSPD) Extraction Associated to MIPS versus MAE Liquid Extraction for the Simultaneous Analysis of PAHs, PCBs and Some Hydroxylated PAHs in Sediments</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=F.%20Portet-Koltalo">F. Portet-Koltalo</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20Tian"> Y. Tian</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20Berger"> I. Berger</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Boulanger-Lecomte"> C. Boulanger-Lecomte</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Benamar"> A. Benamar</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Machour"> N. Machour</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sediments are complex environments which can accumulate a great variety of persistent toxic contaminants such as polychlorobiphenyles (PCBs), polycyclic aromatic hydrocarbons (PAHs) and some of their more toxic degradation metabolites such as hydroxylated PAHs (OH-PAHs). Owing to their composition, fine clayey sediments can be more difficult to extract than soils using conventional solvent extraction processes. So this study aimed to compare the potential of MSPD (matrix solid phase dispersive extraction) to extract PCBs, PAHs and OH-PAHs, in comparison with microwave assisted extraction (MAE). Methodologies: MAE extraction with various solvent mixtures was used to extract PCBs, PAHs and OH-PAHs from sediments in two runs, followed by two GC-MS analyses. MSPD consisted in crushing the dried sediment with dispersive agents, introducing the mixture in cartridges and eluting the target compounds with an appropriate volume of selected solvents. So MSPD combined with cartridges containing MIPs (molecularly imprinted polymers) designed for OH-PAHs was used to extract the three families of target compounds in only one run, followed by parallel analyses in GC-MS for PAHs/PCBs and HPLC-FLD for OH-PAHs. Results: MAE extraction was optimized to extract from clayey sediments, in two runs, PAHs/PCBs in one hand and OH-PAHs in the other hand. Indeed, the best conditions of extractions (mixtures of extracting solvents, temperature) were different if we consider the polarity and the thermodegradability of the different families of target contaminants: PAHs/PCBs were better extracted using an acetone/toluene 50/50 mixture at 130°C whereas OH-PAHs were better extracted using an acetonitrile/toluene 90/10 mixture at 100°C. Moreover, the two consecutive GC-MS analyses contributed to double the total analysis time. A matrix solid phase dispersive (MSPD) extraction procedure was also optimized, with the first objective of increasing the extraction recovery yields of PAHs and PCBs from fine-grained sediment. The crushing time (2-10 min), the nature of the dispersing agents added for purifying and increasing the extraction yields (Florisil, octadecylsilane, 3-chloropropyle, 4-benzylchloride), the nature and the volume of eluting solvents (methylene chloride, hexane, hexane/acetone…) were studied. It appeared that in the best conditions, MSPD was a better extraction method than MAE for PAHs and PCBs, with respectively, mean increases of 8.2% and 71%. This method was also faster, easier and less expensive. But the other advantage of MSPD was that it allowed to introduce easily, just after the first elution process of PAHs/PCBs, a step permitting the selective recovery of OH-PAHs. A cartridge containing MIPs designed for phenols was coupled to the cartridge containing the dispersed sediment, and various eluting solvents, different from those used for PAHs and PCBs, were tested to selectively concentrate and extract OH-PAHs. Thereafter OH-PAHs could be analyzed at the same time than PAHs and PCBs: the OH-PAH extract could be analyzed with HPLC-FLD, whereas the PAHs/PCBs extract was analyzed with GC-MS, adding only few minutes more to the total duration of the analytical process. Conclusion: MSPD associated to MIPs appeared to be an easy, fast and low expensive method, able to extract in one run a complex mixture of toxic apolar and more polar contaminants present in clayey fine-grained sediments, an environmental matrix which is generally difficult to analyze. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=contaminated%20fine-grained%20sediments" title="contaminated fine-grained sediments">contaminated fine-grained sediments</a>, <a href="https://publications.waset.org/abstracts/search?q=matrix%20solid%20phase%20dispersive%20extraction" title=" matrix solid phase dispersive extraction"> matrix solid phase dispersive extraction</a>, <a href="https://publications.waset.org/abstracts/search?q=microwave%20assisted%20extraction" title=" microwave assisted extraction"> microwave assisted extraction</a>, <a href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymers" title=" molecularly imprinted polymers"> molecularly imprinted polymers</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-pollutant%20analysis" title=" multi-pollutant analysis"> multi-pollutant analysis</a> </p> <a href="https://publications.waset.org/abstracts/48037/advantages-of-matrix-solid-phase-dispersive-mspd-extraction-associated-to-mips-versus-mae-liquid-extraction-for-the-simultaneous-analysis-of-pahs-pcbs-and-some-hydroxylated-pahs-in-sediments" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48037.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">353</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1518</span> The Untold Story of the Importance of ‘Insignia Imprinted’ for the Heritage Clay Roof Tiles in Malaysia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20S.%20Sulaiman">M. S. Sulaiman</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Hassan"> N. Hassan</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Aziz"> M. A. Aziz</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20S.%20A.%20Haron"> M. S. A. Haron</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20H.%20A.%20Halim"> J. H. A. Halim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The classic profile of heritage clay roof tiles gives unique characteristics and timeless style to the almost historical building. It is not only designed to meet basic construction needs, offering great performance and durability but also highlights unnoticed stamp impressions, known as ‘insignia imprinted.’ It seems that the insignia imprinted is not significant to all stakeholders, especially in preserving heritage clay roof tiles in Malaysia. They are not even realized the existence and importance of that element, where it represents the cognitive and social character of that particular era. It creates a sense of belongings for the manufacturers regarding their most elementary features, such as a fortress, crown, fauna and etc. This research aims to identify and analyze the late stamp marks on heritage interlocking clay roof tiles in a government heritage building in Malaysia. The methodology used is literature reviews (desktop study), observation on sites, and interviews. Initial findings from the preliminary observation on-site in Peninsular Malaysia show some evidence that the stamp marks appear on the front and back sides of the tile that indicates the year, manufacturer, code numbers, and logos. Almost more than 30 samples of different types of stamp marks were found and collected. Some of which had been described Guichard & Carvin Cie Marsielle St Andre France, Pierre Sacoman St Henry Marsielle, Tuileries Aixoises Les Milles B.D.R France, The Calicut Tile Co Feroke, And B. Pinto & Co Mangalore dated 1865, 1919 and 1936. In view of this abundance of materials, it will lead to the establishment of a comprehensive database consisting of detailed specifications and material performance for future conservation works and maintenance purposes that will sustain for future references. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=clay%20roof%20tiles" title="clay roof tiles">clay roof tiles</a>, <a href="https://publications.waset.org/abstracts/search?q=insignia%20imprinted" title=" insignia imprinted"> insignia imprinted</a>, <a href="https://publications.waset.org/abstracts/search?q=interlocking" title=" interlocking"> interlocking</a>, <a href="https://publications.waset.org/abstracts/search?q=stamp%20mark" title=" stamp mark"> stamp mark</a> </p> <a href="https://publications.waset.org/abstracts/160595/the-untold-story-of-the-importance-of-insignia-imprinted-for-the-heritage-clay-roof-tiles-in-malaysia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/160595.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">72</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1517</span> PVDF-HFP Based Nanocomposite Gel Polymer Electrolytes Dispersed with Zro2 for Li-Ion Batteries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=R.%20Sharma">R. Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Sil"> A. Sil</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Ray"> S. Ray</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nanocomposites gel polymer electrolytes are gaining more and more attention among the researchers worldwide due to their possible applications in various electrochemical devices particularly in solid-state Li-ion batteries. In this work we have investigated the effect of nanofibers on the electrical properties of PVDF-HFP based gel electrolytes. The nanocomposites polymer electrolytes have been synthesized by solution casting technique with 10wt% of ZrO2. By analysis of impedance spectroscopy it has been demonstrated that the incorporation of ZrO2 into PVDF-HFP–(PC+DEC)–LiClO4 gel polymer electrolyte system significantly enhances the ionic conductivity of the electrolyte. The enhancement of ionic conductivity seems to be correlated with the fact that the dispersion of ZrO2 to PVDF-HFP prevents polymer chain reorganization due to the high aspect ratio of ZrO2, resulting in reduction in polymer crystallinity, which gives rise to an increase in ionic conductivity. The decrease of crystallinity of PVDF-HFP due the addition of ZrO2 has been confirmed by XRD. The interaction of ZrO2 with various constituents of polymer electrolytes has been studied by FTIR spectroscopy. TEM results show that the fillers (ZrO2) has distributed uniformly in the polymer electrolytes. Moreover, ZrO2 added gel polymer electrolytes offer better thermal stability as compared to that of ZrO2 free electrolytes as confirmed by TGA analysis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=polymer%20electrolytes" title="polymer electrolytes">polymer electrolytes</a>, <a href="https://publications.waset.org/abstracts/search?q=ZrO2" title=" ZrO2"> ZrO2</a>, <a href="https://publications.waset.org/abstracts/search?q=ionic%20conductivity" title=" ionic conductivity"> ionic conductivity</a>, <a href="https://publications.waset.org/abstracts/search?q=FTIR" title=" FTIR"> FTIR</a> </p> <a href="https://publications.waset.org/abstracts/21340/pvdf-hfp-based-nanocomposite-gel-polymer-electrolytes-dispersed-with-zro2-for-li-ion-batteries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21340.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">474</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1516</span> Single-Molecule Analysis of Structure and Dynamics in Polymer Materials by Super-Resolution Technique</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hiroyuki%20Aoki">Hiroyuki Aoki</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The physical properties of polymer materials are dependent on the conformation and molecular motion of a polymer chain. Therefore, the structure and dynamic behavior of the single polymer chain have been the most important concerns in the field of polymer physics. However, it has been impossible to directly observe the conformation of the single polymer chain in a bulk medium. In the current work, the novel techniques to study the conformation and dynamics of a single polymer chain are proposed. Since a fluorescence method is extremely sensitive, the fluorescence microscopy enables the direct detection of a single molecule. However, the structure of the polymer chain as large as 100 nm cannot be resolved by conventional fluorescence methods because of the diffraction limit of light. In order to observe the single chains, we developed the labeling method of polymer materials with a photo-switchable dye and the super-resolution microscopy. The real-space conformational analysis of single polymer chains with the spatial resolution of 15-20 nm was achieved. The super-resolution microscopy enables us to obtain the three-dimensional coordinates; therefore, we succeeded the conformational analysis in three dimensions. The direct observation by the nanometric optical microscopy would reveal the detailed information on the molecular processes in the various polymer systems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=polymer%20materials" title="polymer materials">polymer materials</a>, <a href="https://publications.waset.org/abstracts/search?q=single%20molecule" title=" single molecule"> single molecule</a>, <a href="https://publications.waset.org/abstracts/search?q=super-resolution%20techniques" title=" super-resolution techniques"> super-resolution techniques</a>, <a href="https://publications.waset.org/abstracts/search?q=conformation" title=" conformation"> conformation</a> </p> <a href="https://publications.waset.org/abstracts/57901/single-molecule-analysis-of-structure-and-dynamics-in-polymer-materials-by-super-resolution-technique" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/57901.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">306</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1515</span> Effects of Polymer Adsorption and Desorption on Polymer Flooding in Waterflooded Reservoir</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sukruthai%20Sapniwat">Sukruthai Sapniwat</a>, <a href="https://publications.waset.org/abstracts/search?q=Falan%20Srisuriyachai"> Falan Srisuriyachai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Polymer Flooding is one of the most well-known methods in Enhanced Oil Recovery (EOR) technology which can be implemented after either primary or secondary recovery, resulting in favorable conditions for the displacement mechanism in order to lower the residual oil in the reservoir. Polymer substances can lower the mobility ratio of the whole process by increasing the viscosity of injected water. Therefore, polymer flooding can increase volumetric sweep efficiency, which leads to a better recovery factor. Moreover, polymer adsorption onto rock surface can help decrease reservoir permeability contrast with high heterogeneity. Due to the reduction of the absolute permeability, effective permeability to water, representing flow ability of the injected fluid, is also reduced. Once polymer is adsorbed onto rock surface, polymer molecule can be desorbed when different fluids are injected. This study is performed to evaluate the effects of the adsorption and desorption process of polymer solutions to yield benefits on the oil recovery mechanism. A reservoir model is constructed by reservoir simulation program called STAR® commercialized by the Computer Modeling Group (CMG). Various polymer concentrations, starting times of polymer flooding process and polymer injection rates were evaluated with selected values of polymer desorption degrees including 0, 25, 50, 75 and 100%. The higher the value, the more adsorbed polymer molecules to return back to flowing fluid. According to the results, polymer desorption lowers polymer consumption, especially at low concentrations. Furthermore, starting time of polymer flooding and injection rate affect the oil production. The results show that waterflooding followed by earlier polymer flooding can increase the oil recovery factor while the higher injection rate also enhances the recovery. Polymer concentration is related to polymer consumption due to the two main benefits of polymer flooding control described above. Therefore, polymer slug size should be optimized based on polymer concentration. Polymer desorption causes polymer re-employment that is previously adsorbed onto rock surface, resulting in an increase of sweep efficiency in the further period of polymer flooding process. Even though waterflooding supports polymer injectivity, water cut at the producer can prematurely terminate the oil production. The injection rate decreases polymer adsorption due to decreased retention time of polymer flooding process. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=enhanced%20oil%20recovery%20technology" title="enhanced oil recovery technology">enhanced oil recovery technology</a>, <a href="https://publications.waset.org/abstracts/search?q=polymer%20adsorption%20and%20desorption" title=" polymer adsorption and desorption"> polymer adsorption and desorption</a>, <a href="https://publications.waset.org/abstracts/search?q=polymer%20flooding" title=" polymer flooding"> polymer flooding</a>, <a href="https://publications.waset.org/abstracts/search?q=reservoir%20simulation" title=" reservoir simulation"> reservoir simulation</a> </p> <a href="https://publications.waset.org/abstracts/61704/effects-of-polymer-adsorption-and-desorption-on-polymer-flooding-in-waterflooded-reservoir" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61704.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">330</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=molecularly%20imprinted%20polymer&page=4">4</a></li> <li class="page-item"><a class="page-link" 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