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Earl W. Sutherland, Jr.
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Sutherland, Jr.</b></font><p><img src="earl-w-sutherland.jpg" height=308 width=220 align=right hspace=10 vspace=10 alt="Earl W. Sutherland, Jr."><b>AKA</b> Earl Wilbur Sutherland, Jr.<p><b>Born:</b> <a href="/lists/841/000106523/" class=proflink>19-Nov</a>-<a href="/lists/914/000105599/" class=proflink>1915</a><br><b>Birthplace:</b> <a href="/geo/143/000130750/" class=proflink>Burlingame, KS</a><br><b>Died:</b> <a href="/lists/952/000106634/" class=proflink>9-Mar</a>-<a href="/lists/484/000106166/" class=proflink>1974</a><br><b>Location of death:</b> <a href="/geo/602/000069395/" class=proflink>Miami, FL</a><br><b>Cause of death:</b> Complications of Surgery<br><b>Remains:</b> Buried, Burlingame City Cemetery, Burlingame, KS<br><p><b>Gender:</b> Male<br><b>Race or Ethnicity:</b> White<br><b>Sexual orientation:</b> Straight<br><b>Occupation:</b> <a href="/lists/179/000068972/" class=proflink>Scientist</a>, <a href="/lists/632/000096344/" class=proflink>Doctor</a><p><b>Nationality:</b> United States<br><b>Executive summary:</b> Hormones mechanisms (cyclic AMP)<p><b>Military service:</b> US Army (battalion surgeon, WWII)<p>American biochemist Earl Sutherland Jr was inspired to pursue medical research when he read a book about <a href="/people/580/000072364/">Louis Pasteur</a>. In World War II he served as a battalion surgeon under <a href="/people/975/000024903/">George S. Patton</a>, and after the war he spent his career studying how hormones regulate body functions. He studied epinephrine with Nobel laureates <a href="/people/135/000128748/">Carl</a> and <a href="/people/144/000128757/">Gerty Cori</a>, and showed how adrenaline regulates the way sugar is broken down, providing a surge of energy when the body is under stress. In his most famous work, he discovered cyclic adenosine 3'5'-monophosphate (cyclic AMP), a "second messenger" which regulates numerous intracellular reactions. Sutherland received the Nobel Prize in Medicine or Physiology in 1971, for "his long study of hormones, the chemical substances that regulate virtually every body function."<p><b>Father:</b> Earl Wilbur Sutherland (owned a dry-goods store)<br><b>Mother:</b> Edith M. Hartshorn Sutherland<br><b>Wife:</b> Mildred Rice Sutherland (m. 1937, div. 1962)<br><b>Wife:</b> Claudia Sebeste Smith Sutherland (assistant dean at Vanderbilt University, m. 1963)<br><p> High School: Burlingame Junior/Senior High School, Burlingame, KS (1932)<br> University: <a href="/edu/661/000079424/">BS Chemistry, Washburn University (1937)</a><br> Medical School: <a href="/edu/630/000079393/">MD, Washington University in St. Louis (1942)</a><br> Teacher: <a href="/edu/630/000079393/">Pharmacology, Washington University in St. Louis (1940-46)</a><br> Teacher: <a href="/edu/630/000079393/">Biochemistry, Washington University in St. Louis (1946-53)</a><br> Professor: <a href="/edu/632/000068428/">Pharmacology, Case Western Reserve University (1953-63)</a><br> Professor: <a href="/edu/646/000068442/">Physiology, Vanderbilt University (1963-73)</a><br> Professor: Biochemistry, University of Miami Florida (1973-74)<br><p> <a href="/honors/045/000111709/">Dickson Prize</a> 1970<br> <a href="/honors/161/000118804/">Lasker Award</a> 1970<br> <a href="/honors/214/000068010/">Nobel Prize for Medicine</a> 1971<br> <a href="/honors/636/000042510/">National Medal of Science</a> 1973<br> <a href="/org/655/000041532/">Alpha Omega Alpha Honor Society</a> <br> <a href="/org/766/000051613/">American Association for the Advancement of Science</a> <br> <a href="/org/790/000055625/">American Chemical Society</a> <br> <a href="/org/972/000084720/">American Heart Association</a> Career Investigator grant (1967)<br> <a href="/org/120/000116769/">American Society for Biochemistry and Molecular Biology</a> <br> <a href="/org/692/000054530/">National Academy of Sciences</a> <br> <a href="/org/457/000041334/">Sigma Xi Scientific Research Society</a> <br><p> <b>Author of books:</b><br> <i>Cyclic AMP</i> (<tt>1971</tt>, with Reginald W. Butcher and G. Alan Robison)<br><p> <br> <p> <table> <tr> <td align=right valign=middle style="padding-right: 5px;"><span style="font-family: Georgia, serif; font-size: 22px; font-style: italic; color: #ff3333;">New!</span><br> <a href="http://mapper.nndb.com/" class="fotmlink" style="font-family: Tahoma, sans-serif; font-size: 10px; font-weight: bold; text-decoration: none; color: #dd0000;">NNDB MAPPER</a></td> <td valign=middle align=right style="border-left: 1px solid #bbb; padding-left: 5px;">Create a map starting with</td> <td valign=middle align=right><a href="http://mapper.nndb.com/start/?id=130590"><img src="/man.gif" border=0 style="padding: 2px;"></a></td> <td align=left valign=middle> <a href="http://mapper.nndb.com/start/?id=130590">Earl W. 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