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class="menu-card"><div _ngcontent-sc258="" class="menu-card-header">FEATURED</div><asco-link _ngcontent-sc258="" _nghost-sc188=""><a _ngcontent-sc188="" rel="noopener" href="https://breakthrough.asco.org"><div _ngcontent-sc258="" class="menu-card-link-inner"><div _ngcontent-sc258="" class="menu-card-image" style="background-image:url(https://s3.amazonaws.com/files.oncologymeetings.org/images/BT24-Skyline-ft-hub-menu-280x145.png);"></div><div _ngcontent-sc258="" class="menu-card-title">2024 ASCO Breakthrough</div><div _ngcontent-sc258="" class="menu-card-desc">ASCO Breakthrough is your gateway to up-to-the-minute clinical research advances across multiple disease sites. 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Learn more.</div></div></a></asco-link></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title active"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Meetings </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://conferences.asco.org/am" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> ASCO Annual Meeting </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://conferences.asco.org/boa" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Best of ASCO </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span 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buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://conferences.asco.org/quality" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> ASCO Quality Care Symposium </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" 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class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://headandnecksymposium.org" target="_blank" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Multidisciplinary Head & Neck Symposium <mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate launch-icon-display align-middle material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">launch</mat-icon></div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.thoracicsymposium.org" target="_blank" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Multidisciplinary Thoracic Cancers Symposium <mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate launch-icon-display align-middle material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">launch</mat-icon></div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://soc-neuro-onc.org/WEB/Event_Content/2024_SNO_ASCO_CNS_Metastases_Conference.aspx" target="_blank" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> SNO/ASCO CNS Metastases Conference <mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate launch-icon-display align-middle material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">launch</mat-icon></div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://vailworkshop.org" target="_blank" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> AACR/ASCO Methods in Clinical Cancer Research Workshop <mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate launch-icon-display align-middle material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">launch</mat-icon></div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/meeting-slides-videos" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Meeting Slides & Videos </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/joint-sessions-endorsements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Joint Sessions & Endorsements </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li></ul></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/joint-sessions-endorsements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Joint Sessions & Endorsements </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li></ul></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/joint-sessions-endorsements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Joint Sessions & Endorsements </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li></ul></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/joint-sessions-endorsements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Joint Sessions & Endorsements </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li></ul></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/joint-sessions-endorsements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Joint Sessions & Endorsements </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li></ul></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/joint-sessions-endorsements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Joint Sessions & Endorsements </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li></ul></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title active"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/training-programs" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Training Programs </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://asco.org/meetings-education/training-programs/quality-training-program" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Quality Training Program </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/training-programs/global-courses" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Global Courses </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/training-programs/global-curriculum" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Global Curriculum Recommendations </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/training-programs/medical-oncology-training-examination" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Medical Oncology In-Training Examination </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/training-programs/resilience-skills-training-program" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Resilience Skills Training Program </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/training-programs/combined-hematology-oncology-hospice-palliative-medicine-training" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Combined Hematology/Oncology and Hospice & Palliative Medicine Training </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/joint-sessions-endorsements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Joint Sessions & Endorsements </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li></ul></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></div><div _ngcontent-sc258="" class="hsr-submenu-item hsr-submenu-item--highlight"><div _ngcontent-sc258="" class="menu-subchildren-helplinks"><div _ngcontent-sc258="" class="menu-subchildren-title">HELPFUL LINKS</div><ul _ngcontent-sc258="" class="menu-subchildren-items"><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/abstract-submissions" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Submit an Abstract </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/meetings-education/meetings/exhibitor-advertiser-information" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><span _ngcontent-sc258="" class="menu-subchildren-item-inner"> Exhibitor Information </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></li><li _ngcontent-sc258="" class="menu-subchildren-item"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" 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mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/practice-patients/cancer-care-standards/standards-safe-handling-hazardous-drugs" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Standards for Safe Handling of Hazardous Drugs </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" 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mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/news-initiatives" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> News & Initiatives </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/news-initiatives/policy-news-analysis" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div 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Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></div></div></div><div _ngcontent-sc258="" class="hsr-submenu"><div _ngcontent-sc258="" class="hsr-submenu-items"><div _ngcontent-sc258="" data-cy="submenu-level-2" class="hsr-submenu-item"><div _ngcontent-sc258="" class="header-submenu-item header-submenu-item--back only-on-sm"><button _ngcontent-sc258="" mat-button="" class="mat-focus-indicator menu-children-title mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">keyboard_arrow_left</mat-icon> Back </span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title active"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/news-initiatives/current-initiatives" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Current Initiatives </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/news-initiatives/current-initiatives/policy-issues-statements" tabindex="0" aria-disabled="false"><span class="mat-button-wrapper"><div _ngcontent-sc258="" class="template-withRouterLink"> Policy Issues & Statements </div></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></a></asco-link></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><asco-link _ngcontent-sc258="" cssclass="mat-basic-button d-inline-block no-hover" buttoncolor="basic" _nghost-sc188=""><a _ngcontent-sc188="" mat-button="" rel="noopener" class="mat-focus-indicator mat-button mat-button-base mat-basic mat-basic-button d-inline-block no-hover _mat-animation-noopable" href="https://www.asco.org/news-initiatives/current-initiatives/health-equity" tabindex="0" 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Committees <mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate align-middle material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">chevron_right</mat-icon></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></span></div><div _ngcontent-sc258="" class="header-submenu-item"><span _ngcontent-sc258="" class="menu-title"><button _ngcontent-sc258="" data-cy="submenu-button" mat-button="" class="mat-focus-indicator d-inline-block mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"> ASCO Patient Advocacy Programs & Opportunities <mat-icon _ngcontent-sc258="" role="img" class="mat-icon notranslate align-middle material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">chevron_right</mat-icon></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span 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_ngcontent-sc188="" href="/abstracts-presentations/234340" class="ng-star-inserted selected-item"><mat-list-item _ngcontent-sc318="" class="mat-list-item mat-focus-indicator mat-list-item-avatar mat-list-item-with-avatar ng-star-inserted"><div class="mat-list-item-content"><div mat-ripple="" class="mat-ripple mat-list-item-ripple"></div><mat-icon _ngcontent-sc318="" role="img" mat-list-icon="" class="mat-icon notranslate mat-list-icon material-icons mat-icon-no-color ng-star-inserted" aria-hidden="true" data-mat-icon-type="font">article</mat-icon><div class="mat-list-text"></div><h5 _ngcontent-sc318="" class="mb-0 mx-3">Abstract</h5></div></mat-list-item></a></asco-link><asco-link _ngcontent-sc318="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" href="/abstracts-presentations/234340/poster" class="ng-star-inserted"><mat-list-item _ngcontent-sc318="" class="mat-list-item mat-focus-indicator mat-list-item-avatar mat-list-item-with-avatar ng-star-inserted"><div class="mat-list-item-content"><div mat-ripple="" class="mat-ripple mat-list-item-ripple"></div><mat-icon _ngcontent-sc318="" role="img" mat-list-icon="" class="mat-icon notranslate mat-list-icon material-icons mat-icon-no-color ng-star-inserted" aria-hidden="true" data-mat-icon-type="font">note</mat-icon><div class="mat-list-text"></div><h5 _ngcontent-sc318="" class="mb-0 mx-3">Poster</h5></div></mat-list-item></a></asco-link></mat-nav-list><hr _ngcontent-sc318="" class="d-none d-lg-block"></div></asco-vertical-tab-navigation></div></asco-side-navigation><asco-abstract-details _ngcontent-sc329="" class="col-xs-12 abstract-details w-100 ng-star-inserted" _nghost-sc321=""><div _ngcontent-sc321="" class="ng-star-inserted"><asco-label-value-list _ngcontent-sc321="" class="col-xs-12" _nghost-sc320=""><h4 _ngcontent-sc320="">Details</h4><ul _ngcontent-sc320="" class="m-0 p-0"><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">First Author</p><asco-link _ngcontent-sc320="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" title="Kaleem Sohail Ahmed " href="/abstracts-presentations/search?q=Kaleem%20Sohail%20Ahmed%20" target="_self" class="ng-star-inserted"><span _ngcontent-sc320="" class="ng-star-inserted">Kaleem Sohail Ahmed </span></a></asco-link></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Meeting</p><asco-link _ngcontent-sc320="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" title="2024 ASCO Annual Meeting" href="/abstracts-presentations/search?q=*&filters=%7B%22meetingTypeName%22:%5B%7B%22key%22:%22ASCO%20Annual%20Meeting%22%7D%5D,%22meetingYear%22:%5B%7B%22key%22:%222024%22%7D%5D%7D" target="_self" class="ng-star-inserted"><span _ngcontent-sc320="" class="ng-star-inserted">2024 ASCO Annual Meeting</span></a></asco-link></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Session Type</p><asco-link _ngcontent-sc320="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" title="Poster Session" href="/abstracts-presentations/search?q=*&filters=%7B%22sessionType%22:%5B%7B%22key%22:%22Poster%20Session%22%7D%5D%7D" target="_self" class="ng-star-inserted"><span _ngcontent-sc320="" class="ng-star-inserted">Poster Session</span></a></asco-link></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Session Title</p><asco-link _ngcontent-sc320="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" title="Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary" href="/2024-asco-annual-meeting/15830?presentation=234340#234340" target="_blank" class="ng-star-inserted"><span _ngcontent-sc320="" class="ng-star-inserted">Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary</span></a></asco-link></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Track</p><asco-link _ngcontent-sc320="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" title="Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary" href="/abstracts-presentations/search?q=*&filters=%7B%22track%22:%5B%7B%22key%22:%22Gastrointestinal%20Cancer%E2%80%94Gastroesophageal,%20Pancreatic,%20and%20Hepatobiliary%22%7D%5D%7D" target="_self" class="ng-star-inserted"><span _ngcontent-sc320="" class="ng-star-inserted">Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary</span></a></asco-link></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Sub Track</p><asco-link _ngcontent-sc320="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" title="Pancreatic Cancer - Local-Regional Disease" href="/abstracts-presentations/search?q=*&filters=%7B%22track%22:%5B%7B%22key%22:%22Pancreatic%20Cancer%20-%20Local-Regional%20Disease%22%7D%5D%7D" target="_self" class="ng-star-inserted"><span _ngcontent-sc320="" class="ng-star-inserted">Pancreatic Cancer - Local-Regional Disease</span></a></asco-link></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Citation</p><p _ngcontent-sc320="" class="label-value-list__item__value ng-star-inserted">J Clin Oncol 42, 2024 (suppl 16; abstr 4169)</p></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">DOI</p><asco-link _ngcontent-sc320="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" rel="noopener" href="https://doi.org/10.1200/JCO.2024.42.16_suppl.4169" target="_blank" title="10.1200/JCO.2024.42.16_suppl.4169" class="ng-star-inserted"><span _ngcontent-sc320="" class="ng-star-inserted">10.1200/JCO.2024.42.16_suppl.4169</span></a></asco-link></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Abstract #</p><p _ngcontent-sc320="" class="label-value-list__item__value ng-star-inserted">4169</p></div></li><li _ngcontent-sc320="" class="label-value-list__item ng-star-inserted"><div _ngcontent-sc320="" class="ng-star-inserted"><p _ngcontent-sc320="" class="label-value-list__item__label">Poster Bd #</p><p _ngcontent-sc320="" class="label-value-list__item__value ng-star-inserted">149</p></div></li></ul></asco-label-value-list></div></asco-abstract-details></div></div></div><div _ngcontent-sc329="" class="col-md-1 col-lg-1"></div><div _ngcontent-sc329="" class="presentation_details__main col-md-7 col-lg-8"><asco-abstract _ngcontent-sc329="" _nghost-sc324="" class="ng-star-inserted"><div _ngcontent-sc324="" class="ng-star-inserted"><div _ngcontent-sc324="" class="presentation-details__abstract_container ng-star-inserted"><h4 _ngcontent-sc324="" text-asco-black="">Authors</h4><div _ngcontent-sc324="" class="ng-star-inserted"><asco-profile-card _ngcontent-sc324="" _nghost-sc323=""><div _ngcontent-sc323="" class="d-flex mb-2 profile-card"><span _ngcontent-sc323=""><asco-avatar _ngcontent-sc323="" _nghost-sc187=""><div _ngcontent-sc187="" class="avatar"><div _ngcontent-sc187="" class="avatar__image-container small"><mat-icon _ngcontent-sc187="" role="img" aria-hidden="false" class="mat-icon notranslate material-icons mat-icon-no-color ng-star-inserted" aria-label="Avatar Image" data-mat-icon-type="font">person</mat-icon></div></div></asco-avatar></span><span _ngcontent-sc323="" class="ml-2 w-100 align-self-center avatar-info"><h5 _ngcontent-sc323="" class="m-0 p-0 text-14">Kaleem Sohail Ahmed </h5><p _ngcontent-sc323="" class="m-0 p-0 text-12">Department of Surgery, University of Wisconsin - Madison, Madison, WI</p></span><div _ngcontent-sc323="" class="pwa-overlay"><asco-pwa-overlay-trigger _ngcontent-sc323="" _nghost-sc191=""><div _ngcontent-sc191=""><button _ngcontent-sc191="" mat-button="" class="mat-focus-indicator menu__item mat-button mat-button-base _mat-animation-noopable"><span class="mat-button-wrapper"><mat-icon _ngcontent-sc191="" role="img" class="mat-icon notranslate material-icons mat-icon-no-color" aria-hidden="true" data-mat-icon-type="font">info_outline</mat-icon><span _ngcontent-sc191="" class="menu__item__text"> </span></span><span matripple="" class="mat-ripple mat-button-ripple"></span><span class="mat-button-focus-overlay"></span></button></div></asco-pwa-overlay-trigger></div></div></asco-profile-card></div><p _ngcontent-sc324="" class="mt-3 mb-4 ng-star-inserted"><asco-safe-html _ngcontent-sc324="" _nghost-sc273=""><div _ngcontent-sc273="" class="safe-html">Kaleem Sohail Ahmed , Sheriff M Issaka , Clayton Thomas Marcinak , Syed Nabeel Zafar </div></asco-safe-html></p><h6 _ngcontent-sc324="" class="ng-star-inserted">Organizations</h6><p _ngcontent-sc324="" class="ng-star-inserted"><asco-safe-html _ngcontent-sc324="" _nghost-sc273=""><div _ngcontent-sc273="" class="safe-html">Department of Surgery, University of Wisconsin - Madison, Madison, WI, Department of Surgery, University of Wisconsin–Madison, Madison, WI, Division of Surgical Oncology, Department of Surgery, University of Wisconsin–Madison, Madison, WI</div></asco-safe-html></p><asco-link _ngcontent-sc324="" _nghost-sc188="" class="ng-star-inserted"><a _ngcontent-sc188="" rel="noopener" href="https://coi.asco.org/Report/ViewAbstractCOI?id=463108" class="ng-star-inserted">Abstract Disclosures</a></asco-link><div _ngcontent-sc324="" class="mt-5 ng-star-inserted"><h4 _ngcontent-sc324="">Research Funding</h4><p _ngcontent-sc324="" class="mb-0"><asco-safe-html _ngcontent-sc324="" _nghost-sc273="" class="ng-star-inserted"><div _ngcontent-sc273="" class="safe-html">NIH-NCI </div></asco-safe-html></p></div><asco-safe-html _ngcontent-sc324="" _nghost-sc273="" class="ng-star-inserted"><div _ngcontent-sc273="" class="safe-html"><p> <b>Background:</b> Pancreatic ductal adenocarcinoma (PDAC) is the second leading cause of cancer-related deaths in the US. There is a need to improve risk-stratification of patients to facilitate treatment decisions. Novel datasets such as the American Society of Clinical Oncology (ASCO)’s CancerLinQ Discovery (CLQD) combined with machine learning (ML) methods provide an opportunity to generate new insights from “real-world data” (RWD) to study patient outcomes. The objective of this study was to develop an ML model using RWD to predict 1-year survival (1YS) for patients undergoing pancreatectomy for PDAC. <b>Methods:</b> Using the CLQD database, we identified patients diagnosed with PDAC who had undergone surgical resection between July 1998 and May 2021. Patients with complete data on procedure and tumor characteristics were included. Patients lost to follow-up within 12 months of surgery were excluded. We trained a multivariable Logistic Regression (LR) for baseline comparison. Gradient Boosting Classifier (GBC) and Random Forest (RF) models were then trained on demographic and clinico-pathologic data, with and without pre-operative laboratory (lab) data. GBC-1 and RF-1 were trained only on demographic and clinico-pathologic data (n=1440). GBC-2 and RF-2 were trained on a subset of patients who had non-missing lab data (n=669). We performed a one-way ANOVA to compare the area-under-the-curve (AUC) scores for each GBC and RF model to the corresponding LR. <b>Results:</b> Of the 1440 patients analyzed, 44.7% were male, 53.6% were White, and the mean age was 69.7 ± 10.9 years. Majority had a T3-stage tumor (53.7%) and 70.3% received either neoadjuvant, adjuvant, delayed and/or recurrent chemotherapy. Unadjusted median OS was 16.5 months [95% CI: 15.1-17.6], and 1YS was 60.8% [95% CI: 58.2-63.3]. GBC and RF models were able to outperform the baseline LRs (Table 1). RF-2 and LR-2 performed the best (AUC: 0.83 each) with lab data, followed by RF-1 (AUC: 0.81) without lab data. Factors that were most predictive of survival were: receipt of chemotherapy, tumor size, pre-operative BMI, age, and pre-operative neutrophil count, serum cholesterol, and serum CA-19-9 levels. <b>Conclusions:</b> In this study, we show that ML models using clinicopathologic, demographic, and laboratory data provide more accurate prediction of 1 year survival than prior strategies. Such models can be used to identify patients at high risk for poor outcomes following pancreatectomy and alternative treatments may be offered. </p><table class="mtgabstract"><caption class="mtgabstract-table-title"><p>Model performance with and without pre-operative laboratory data.</p></caption><thead class="mtgabstract"><tr><th class="border-bottom align-left">Model</th><th class="border-bottom">Feature Set</th><th class="border-bottom">AUC Score</th></tr></thead><tbody><tr><td class="row-heading">LR-1</td><td>Full Dataset, Without Labs (n=1440)</td><td>AUC = 0.78</td></tr><tr><td class="row-heading">RF-1</td><td>Full Dataset, Without Labs (n=1440)</td><td>AUC = 0.81</td></tr><tr><td class="row-heading">GBC-1</td><td>Full Dataset, Without Labs (n=1440)</td><td>AUC = 0.79</td></tr><tr><td class="row-heading">LR-2</td><td>Limited Dataset, With Labs (n=669)</td><td>AUC = 0.83</td></tr><tr><td class="row-heading">RF-2</td><td>Limited Dataset, With Labs (n=669)</td><td>AUC =0.83</td></tr><tr><td class="row-heading">GBC-2</td><td>Limited Dataset, With Labs (n=669)</td><td>AUC = 0.82</td></tr></tbody></table><p></p></div></asco-safe-html></div></div></asco-abstract><div _ngcontent-sc329="" class="py-3 ng-star-inserted"><div _ngcontent-sc329="" class="font-italic"> This material on this page is ©2024 American Society of Clinical Oncology, all rights reserved. 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MD&q;,&q;pictureUrl&q;:null,&q;__typename&q;:&q;ProfilePersonalInfo&q;},&q;organizationInfo&q;:null,&q;socialNetworkingInfo&q;:{&q;twitterHandle&q;:null,&q;__typename&q;:&q;ProfileSocialNetworkingInfo&q;},&q;emails&q;:[{&q;emailValue&q;:&q;marcinak@wisc.edu&q;,&q;__typename&q;:&q;ProfileEmail&q;},{&q;emailValue&q;:&q;clayton.marcinak@gmail.com&q;,&q;__typename&q;:&q;ProfileEmail&q;}],&q;__typename&q;:&q;Profile&q;},&q;__typename&q;:&q;PersonRole&q;},{&q;role&q;:&q;Author&q;,&q;order&q;:4,&q;displayName&q;:&q;Syed Nabeel Zafar &q;,&q;publicationOrganization&q;:&q;Division of Surgical Oncology, Department of Surgery, University of Wisconsin&a;#x2013;Madison, Madison, WI&q;,&q;contactPresenterUrl&q;:{&q;path&q;:&q;/AM2024/Session#/compose-message/650781&q;,&q;target&q;:null,&q;title&q;:null,&q;fqdn&q;:&q;meetingnetworking.asco.org&q;,&q;queryParams&q;:&q;{}&q;,&q;__typename&q;:&q;Url&q;},&q;profile&q;:{&q;personalInfo&q;:{&q;fullNameWithDesignation&q;:&q;Syed Nabeel Zafar, MBBS, MPH&q;,&q;pictureUrl&q;:{&q;path&q;:&q;/profile/C55E68AE-B95E-4A87-B4C4-A15C17B5E773.jpg&q;,&q;target&q;:&q;&q;,&q;title&q;:&q;Syed Nabeel Zafar&q;,&q;fqdn&q;:&q;ascoapp.blob.core.windows.net&q;,&q;queryParams&q;:&q;{\&q;1600745515078\&q;:\&q;\&q;}&q;,&q;__typename&q;:&q;Url&q;},&q;__typename&q;:&q;ProfilePersonalInfo&q;},&q;organizationInfo&q;:null,&q;socialNetworkingInfo&q;:{&q;twitterHandle&q;:&q;&q;,&q;__typename&q;:&q;ProfileSocialNetworkingInfo&q;},&q;emails&q;:[{&q;emailValue&q;:&q;szafar2@wisc.edu&q;,&q;__typename&q;:&q;ProfileEmail&q;},{&q;emailValue&q;:&q;andrewsa@surgery.wisc.edu&q;,&q;__typename&q;:&q;ProfileEmail&q;},{&q;emailValue&q;:&q;szafar2@wisc.edu&q;,&q;__typename&q;:&q;ProfileEmail&q;}],&q;__typename&q;:&q;Profile&q;},&q;__typename&q;:&q;PersonRole&q;}],&q;fullBody&q;:&q;&l;p&g;\r\n &l;b&g;Background:&l;/b&g; Pancreatic ductal adenocarcinoma (PDAC) is the second leading cause of cancer-related deaths in the US. There is a need to improve risk-stratification of patients to facilitate treatment decisions. Novel datasets such as the American Society of Clinical Oncology (ASCO)&a;#x2019;s CancerLinQ Discovery (CLQD) combined with machine learning (ML) methods provide an opportunity to generate new insights from &a;#x201C;real-world data&a;#x201D; (RWD) to study patient outcomes. The objective of this study was to develop an ML model using RWD to predict 1-year survival (1YS) for patients undergoing pancreatectomy for PDAC. &l;b&g;Methods:&l;/b&g; Using the CLQD database, we identified patients diagnosed with PDAC who had undergone surgical resection between July 1998 and May 2021. Patients with complete data on procedure and tumor characteristics were included. Patients lost to follow-up within 12 months of surgery were excluded. We trained a multivariable Logistic Regression (LR) for baseline comparison. Gradient Boosting Classifier (GBC) and Random Forest (RF) models were then trained on demographic and clinico-pathologic data, with and without pre-operative laboratory (lab) data. GBC-1 and RF-1 were trained only on demographic and clinico-pathologic data (n=1440). GBC-2 and RF-2 were trained on a subset of patients who had non-missing lab data (n=669). We performed a one-way ANOVA to compare the area-under-the-curve (AUC) scores for each GBC and RF model to the corresponding LR. &l;b&g;Results:&l;/b&g; Of the 1440 patients analyzed, 44.7% were male, 53.6% were White, and the mean age was 69.7 &a;#xB1; 10.9 years. Majority had a T3-stage tumor (53.7%) and 70.3% received either neoadjuvant, adjuvant, delayed and/or recurrent chemotherapy. Unadjusted median OS was 16.5 months [95% CI: 15.1-17.6], and 1YS was 60.8% [95% CI: 58.2-63.3]. GBC and RF models were able to outperform the baseline LRs (Table 1). RF-2 and LR-2 performed the best (AUC: 0.83 each) with lab data, followed by RF-1 (AUC: 0.81) without lab data. Factors that were most predictive of survival were: receipt of chemotherapy, tumor size, pre-operative BMI, age, and pre-operative neutrophil count, serum cholesterol, and serum CA-19-9 levels. &l;b&g;Conclusions:&l;/b&g; In this study, we show that ML models using clinicopathologic, demographic, and laboratory data provide more accurate prediction of 1 year survival than prior strategies. Such models can be used to identify patients at high risk for poor outcomes following pancreatectomy and alternative treatments may be offered. &l;table class=\&q;mtgabstract\&q;&g;&l;caption class=\&q;mtgabstract-table-title\&q;&g;&l;p&g;Model performance with and without pre-operative laboratory data.&l;/p&g;&l;/caption&g;&l;thead class=\&q;mtgabstract\&q;&g;&l;tr&g;&l;th class=\&q;border-bottom align-left\&q;&g;Model&l;/th&g;&l;th class=\&q;border-bottom\&q;&g;Feature Set&l;/th&g;&l;th class=\&q;border-bottom\&q;&g;AUC Score&l;/th&g;&l;/tr&g;&l;/thead&g;&l;tbody&g;&l;tr&g;&l;td class=\&q;row-heading\&q;&g;LR-1&l;/td&g;&l;td&g;Full Dataset, Without Labs (n=1440)&l;/td&g;&l;td&g;AUC = 0.78&l;/td&g;&l;/tr&g;&l;tr&g;&l;td class=\&q;row-heading\&q;&g;RF-1&l;/td&g;&l;td&g;Full Dataset, Without Labs (n=1440)&l;/td&g;&l;td&g;AUC = 0.81&l;/td&g;&l;/tr&g;&l;tr&g;&l;td class=\&q;row-heading\&q;&g;GBC-1&l;/td&g;&l;td&g;Full Dataset, Without Labs (n=1440)&l;/td&g;&l;td&g;AUC = 0.79&l;/td&g;&l;/tr&g;&l;tr&g;&l;td class=\&q;row-heading\&q;&g;LR-2&l;/td&g;&l;td&g;Limited Dataset, With Labs (n=669)&l;/td&g;&l;td&g;AUC = 0.83&l;/td&g;&l;/tr&g;&l;tr&g;&l;td class=\&q;row-heading\&q;&g;RF-2&l;/td&g;&l;td&g;Limited Dataset, With Labs (n=669)&l;/td&g;&l;td&g;AUC =0.83&l;/td&g;&l;/tr&g;&l;tr&g;&l;td class=\&q;row-heading\&q;&g;GBC-2&l;/td&g;&l;td&g;Limited Dataset, With Labs (n=669)&l;/td&g;&l;td&g;AUC = 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