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Search results for: biosystems engineering

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3037</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: biosystems engineering</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3037</span> Associations of the FTO Gene Polymorphism with Obesity and Metabolic Syndrome in Lithuanian Adult Population</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alina%20Smalinskiene%20Janina%20Petkeviciene">Alina Smalinskiene Janina Petkeviciene</a>, <a href="https://publications.waset.org/abstracts/search?q=Jurate%20Klumbiene"> Jurate Klumbiene</a>, <a href="https://publications.waset.org/abstracts/search?q=Vilma%20Kriaucioniene"> Vilma Kriaucioniene</a>, <a href="https://publications.waset.org/abstracts/search?q=Vaiva%20Lesauskaite"> Vaiva Lesauskaite</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The worldwide prevalence of obesity has been increasing dramatically in the last few decades, and Lithuania is no exception. In 2012, every fifth adult (19% of men and 20.5 % of women) was obese and every third was overweight Association studies have highlighted the influence of SNPs in obesity, with particular focus on FTO rs9939609. Thus far, no data on the possible association of this SNP to obesity in the adult Lithuanian population has been reported. Here, for the first time, we demonstrate an association between the FTO rs9939609 homozygous AA genotype and increased BMI when compared to homozygous TT. Furthermore, a positive association was determined between the FTO rs9939609 variant and risk of metabolic syndrome. Background: This study aimed to examine the associations between the fat mass and obesity associated (FTO) gene rs9939609 variant with obesity and metabolic syndrome in Lithuanian adult population. Materials and Methods: A cross-sectional health survey was carried out in randomly selected municipalities of Lithuania. The random sample was obtained from lists of 25–64 year-old inhabitants. The data from 1020 subjects were analysed. The rs9939609 SNP of the FTO gene was assessed using TaqMan assays (Applied Biosystems, Foster City, CA, USA). The Applied Biosystems 7900HT Real-Time Polymerase Chain Reaction System was used for detecting the SNPs. Results: The carriers of the AA genotype had the highest mean values of BMI and waist circumference (WC) and the highest risk of obesity. Interactions ‘genotype x age’ and ‘genotype x physical activity’ in determining BMI and WC were shown. Neither lipid and glucose levels, nor blood pressure were associated with the rs9939609 independently of BMI. In the age group of 25-44 years, association between the FTO genotypes and metabolic syndrome was found. Conclusion: The FTO rs9939609 variant was significantly associated with BMI and WC, and with the risk of obesity in Lithuanian population. The FTO polymorphism might have a greater influence on weight status in younger individuals and in subjects with a low level of physical activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=obesity%20metabolic%20syndrome" title="obesity metabolic syndrome">obesity metabolic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=FTO%20gene" title=" FTO gene"> FTO gene</a>, <a href="https://publications.waset.org/abstracts/search?q=polymorphism" title=" polymorphism"> polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=Lithuania" title=" Lithuania"> Lithuania</a> </p> <a href="https://publications.waset.org/abstracts/27295/associations-of-the-fto-gene-polymorphism-with-obesity-and-metabolic-syndrome-in-lithuanian-adult-population" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27295.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">430</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3036</span> Optimization Model for Support Decision for Maximizing Production of Mixed Fresh Fruit Farms</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Andr%C3%A9s%20I.%20%C3%81vila">Andrés I. Ávila</a>, <a href="https://publications.waset.org/abstracts/search?q=Patricia%20Aros"> Patricia Aros</a>, <a href="https://publications.waset.org/abstracts/search?q=C%C3%A9sar%20San%20Mart%C3%ADn"> César San Martín</a>, <a href="https://publications.waset.org/abstracts/search?q=Elizabeth%20Kehr"> Elizabeth Kehr</a>, <a href="https://publications.waset.org/abstracts/search?q=Yovana%20Leal"> Yovana Leal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Planning models for fresh products is a very useful tool for improving the net profits. To get an efficient supply chain model, several functions should be considered to get a complete simulation of several operational units. We consider a linear programming model to help farmers to decide if it is convenient to choose what area should be planted for three kinds of export fruits considering their future investment. We consider area, investment, water, productivity minimal unit, and harvest restrictions to develop a monthly based model to compute the average income in five years. Also, conditions on the field as area, water availability, and initial investment are required. Using the Chilean costs and dollar-peso exchange rate, we can simulate several scenarios to understand the possible risks associated to this market. Also, this tool help to support decisions for government and individual farmers. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=mixed%20integer%20problem" title="mixed integer problem">mixed integer problem</a>, <a href="https://publications.waset.org/abstracts/search?q=fresh%20fruit%20production" title=" fresh fruit production"> fresh fruit production</a>, <a href="https://publications.waset.org/abstracts/search?q=support%20decision%20model" title=" support decision model"> support decision model</a>, <a href="https://publications.waset.org/abstracts/search?q=agricultural%20and%20biosystems%20engineering" title=" agricultural and biosystems engineering"> agricultural and biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/26591/optimization-model-for-support-decision-for-maximizing-production-of-mixed-fresh-fruit-farms" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/26591.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">438</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3035</span> Ceramic Composites and Its Applications for Pb Adsorption</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=C.%20L.%20Popa">C. L. Popa</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20L.%20Iconaru"> S. L. Iconaru</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Costescu"> A. Costescu</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20S.%20Ciobanu"> C. S. Ciobanu</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Motelica%20Heino"> M. Motelica Heino</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Guegan"> R. Guegan</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Predoi"> D. Predoi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Surface functionalization of ceramic composites with a special focus on tetraethyl orthosilicate (TEOS) and hydroxyapatite (HAp) is discoursed. Mesoporous ceramic HAp-TEOS composites were prepared by the incorporation of hydroxyapatite into tetraethyl orthosilicate by sol-gel method. The resulting samples were analysed by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared (FT-IR) spectroscopy, and Raman spectroscopy and nitrogen physisorption. The removal of Pb2+ ions from aqueous solutions was evaluated using Atomic Absorbtion Spectroscopy (AAS). Removal experiments of Pb2+ ions were carried out in aqueous solutions with controlled Pb2+ at pH ~ 3 and pH ~ 5. After removal experiment of Pb2+ at pH 3 and pH 5, porous hydroxyapatite nanoparticles is transformed into PbHAp_3 and PbHAp_5 via the adsorption of Pb2+ ions followed by the cation exchange reaction. The diffraction patterns show that THAp nanoparticles were successfully coated with teos without any structural changes. On the other, the AAS analysis showed that THAp can be useful in the removal Pb2+ from water contaminated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=teos" title="teos">teos</a>, <a href="https://publications.waset.org/abstracts/search?q=hydroxyapatite" title=" hydroxyapatite"> hydroxyapatite</a>, <a href="https://publications.waset.org/abstracts/search?q=environment%20applications" title=" environment applications"> environment applications</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/2457/ceramic-composites-and-its-applications-for-pb-adsorption" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2457.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">384</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3034</span> Investigation of Biofilm Formation in Clinical Strains of Klebsiella pneumoniae and Klebsiella rhinoscleromatis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gulcan%20Sahal">Gulcan Sahal</a>, <a href="https://publications.waset.org/abstracts/search?q=Nermin%20Hande%20Avcioglu"> Nermin Hande Avcioglu</a>, <a href="https://publications.waset.org/abstracts/search?q=Isil%20Seyis%20Bilkay"> Isil Seyis Bilkay</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Klebsiella species which are natural colonizers of human upper respiratory and human gastrointestinal tracts are also responsible for every reoccurring nosocomial infections by means of having ability to form slimy layers known as biofilm on many surfaces. Therefore, in this study, investigation of biofilm formation in K. pneumoniae and K. rhinoscleromatis and examination of each Klebsiella strains’ clinical information in the light of their biofilm formation results were aimed. In this respect, biofilm formation of Klebsiella strains was analyzed via crystal violet binding assay. According to our results, biofilm formation levels of K. pneumoniae and K. rhinoscleromatis strains were different from each other. Additionally, in comparison to K. rhinoscleromatis strains, K. pneumoniae was observed to include higher amounts of strong biofilm forming strains. Besides, it was also seen that clinical information of patients from which strong biofilm forming Klebsiella strains were isolated were similar to each other. Our results indicate that there should be more precautions against K. pneumoniae which includes higher amount of strong biofilm forming strains. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biofilm%20formation" title="biofilm formation">biofilm formation</a>, <a href="https://publications.waset.org/abstracts/search?q=Klebsiella%20pneumoniae" title=" Klebsiella pneumoniae"> Klebsiella pneumoniae</a>, <a href="https://publications.waset.org/abstracts/search?q=Klebsiella%20rhinoscleromatis" title=" Klebsiella rhinoscleromatis"> Klebsiella rhinoscleromatis</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/8310/investigation-of-biofilm-formation-in-clinical-strains-of-klebsiella-pneumoniae-and-klebsiella-rhinoscleromatis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8310.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">390</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3033</span> Risk Assessment Results in Biogas Production from Agriculture Biomass</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sandija%20Zeverte-Rivza">Sandija Zeverte-Rivza</a>, <a href="https://publications.waset.org/abstracts/search?q=Irina%20Pilvere"> Irina Pilvere</a>, <a href="https://publications.waset.org/abstracts/search?q=Baiba%20Rivza"> Baiba Rivza</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The use of renewable energy sources incl. biogas has become topical in accordance with the increasing demand for energy, decrease of fossil energy resources and the efforts to reduce greenhouse gas emissions as well as to increase energy independence from the territories where fossil energy resources are available. As the technologies of biogas production from agricultural biomass develop, risk assessment and risk management become necessary for farms producing such a renewable energy. The need for risk assessments has become particularly topical when discussions on changing the biogas policy in the EU take place, which may influence the development of the sector in the future, as well as the operation of existing biogas facilities and their income level. The current article describes results of the risk assessment for farms producing biomass from agriculture biomass in Latvia, the risk assessment system included 24 risks, that affect the whole biogas production process and the obtained results showed the high significance of political and production risks. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biogas%20production" title="biogas production">biogas production</a>, <a href="https://publications.waset.org/abstracts/search?q=risks" title=" risks"> risks</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20assessment" title=" risk assessment"> risk assessment</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/6649/risk-assessment-results-in-biogas-production-from-agriculture-biomass" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/6649.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">415</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3032</span> Reliability of Dry Tissues Sampled from Exhumed Bodies in DNA Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=V.%20Agostini">V. Agostini</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Gino"> S. Gino</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Inturri"> S. Inturri</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Piccinini"> A. Piccinini</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In cases of corpse identification or parental testing performed on exhumed alleged dead father, usually, we seek and acquire organic samples as bones and/or bone fragments, teeth, nails and muscle’s fragments. The DNA analysis of these cadaveric matrices usually leads to identifying success, but it often happens that the results of the typing are not satisfactory with highly degraded, partial or even non-interpretable genetic profiles. To aggravate the interpretative panorama deriving from the analysis of such 'classical' organic matrices, we must add a long and laborious treatment of the sample that starts from the mechanical fragmentation up to the protracted decalcification phase. These steps greatly increase the chance of sample contamination. In the present work, instead, we want to report the use of 'unusual' cadaveric matrices, demonstrating that their forensic genetics analysis can lead to better results in less time and with lower costs of reagents. We report six case reports, result of on-field experience, in which eyeswabs and cartilage were sampled and analyzed, allowing to obtain clear single genetic profiles, useful for identification purposes. In all cases we used the standard DNA tissue extraction protocols (as reported on the user manuals of the manufacturers such as QIAGEN or Invitrogen- Thermo Fisher Scientific), thus bypassing the long and difficult phases of mechanical fragmentation and decalcification of bones' samples. PCR was carried out using PowerPlex® Fusion System kit (Promega), and capillary electrophoresis was carried out on an ABI PRISM® 310 Genetic Analyzer (Applied Biosystems®), with GeneMapper ID v3.2.1 (Applied Biosystems®) software. The software Familias (version 3.1.3) was employed for kinship analysis. The genetic results achieved have proved to be much better than the analysis of bones or nails, both from the qualitative and quantitative point of view and from the point of view of costs and timing. This way, by using the standard procedure of DNA extraction from tissue, it is possible to obtain, in a shorter time and with maximum efficiency, an excellent genetic profile, which proves to be useful and can be easily decoded for later paternity tests and/or identification of human remains. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=DNA" title="DNA">DNA</a>, <a href="https://publications.waset.org/abstracts/search?q=eye%20swabs%20and%20cartilage" title=" eye swabs and cartilage"> eye swabs and cartilage</a>, <a href="https://publications.waset.org/abstracts/search?q=identification%20human%20remains" title=" identification human remains"> identification human remains</a>, <a href="https://publications.waset.org/abstracts/search?q=paternity%20testing" title=" paternity testing"> paternity testing</a> </p> <a href="https://publications.waset.org/abstracts/93992/reliability-of-dry-tissues-sampled-from-exhumed-bodies-in-dna-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/93992.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">109</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3031</span> Determination of Biofilm Formation in Different Clinical Candida Species and Investigation of Effects of Some Plant Substances on These Biofilms</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gulcan%20Sahal">Gulcan Sahal</a>, <a href="https://publications.waset.org/abstracts/search?q=Isil%20Seyis%20Bilkay"> Isil Seyis Bilkay</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Candida species which often exist as commensal microorganisms in healthy individuals are major causes of important infections, especially in AIDS and immunocompromised patients, by means of their biofilm formation abilities. Therefore, in this study, determination of biofilm formation in different clinical strains of Candida species, investigation of strong biofilm forming Candida strains, examination of clinical information of each strong and weak biofilm forming Candida strains and investigation of some plant substances’ effects on biofilm formation of strong biofilm forming strains were aimed. In this respect, biofilm formation of Candida strains was analyzed via crystal violet binding assay. According to our results, biofilm levels of strains belong to different Candida species were different from each other. Additionally, it is also found that some plant substances effect biofilm formation. All these results indicate that, as well as C. albicans strains, other non-albicans Candida species also emerge as causative agents of infections and have biofilm formation abilities. In addition, usage of some plant substances in different concentrations may provide a new treatment against biofilm related Candida infections. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anti-biofilm" title="anti-biofilm">anti-biofilm</a>, <a href="https://publications.waset.org/abstracts/search?q=biofilm%20formation" title=" biofilm formation"> biofilm formation</a>, <a href="https://publications.waset.org/abstracts/search?q=Candida%20species" title=" Candida species"> Candida species</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/8322/determination-of-biofilm-formation-in-different-clinical-candida-species-and-investigation-of-effects-of-some-plant-substances-on-these-biofilms" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8322.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">483</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3030</span> Speciation and Bioavailability of Heavy Metals in Greenhouse Soils</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bulent%20Topcuoglu">Bulent Topcuoglu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Repeated amendments of organic matter and intensive use of fertilizers, metal-enriched chemicals and biocides may cause soil and environmental pollution in greenhouses. Specially, the impact of heavy metal pollution of soils on food metal content and underground water quality has become a public concern. Due to potential toxicity of heavy metals to human life and environment, determining the chemical form of heavy metals in greenhouse soils is an important approach of chemical characterization and can provide useful information on its mobility and bioavailability. A sequential extraction procedure was used to estimate the availability of heavy metals (Zn, Cd, Ni, Pb and Cr) in greenhouse soils of Antalya Aksu. Zn was predominantly associated with Fe-Mn oxide fraction, major portion of Cd associated with carbonate and organic matter fraction, a major portion of (>65 %) Ni and Cr were largely associated with Fe-Mn oxide and residual fractions and Pb was largely associated with organic matter and Fe-Mn oxide fractions. Results of the present study suggest that the mobility and bioavailability of metals probably increase in the following order: Cr < Pb < Ni < Cd < Zn. Among the elements studied, Zn and Cd appeared to be the most readily soluble and potentially bioavailable metals and these metals may carry a potential risk for metal transfer in food chain and contamination to ground water. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=metal%20speciation" title="metal speciation">metal speciation</a>, <a href="https://publications.waset.org/abstracts/search?q=metal%20mobility" title=" metal mobility"> metal mobility</a>, <a href="https://publications.waset.org/abstracts/search?q=greenhouse%20soils" title=" greenhouse soils"> greenhouse soils</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/5068/speciation-and-bioavailability-of-heavy-metals-in-greenhouse-soils" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/5068.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">416</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3029</span> Antibiotic Resistance of Enterococci Isolated from Raw Cow Milk</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Margita%20%C4%8Canigov%C3%A1">Margita Čanigová</a>, <a href="https://publications.waset.org/abstracts/search?q=Jana%20Ra%C4%8Dkov%C3%A1"> Jana Račková</a>, <a href="https://publications.waset.org/abstracts/search?q=Miroslav%20Kro%C4%8Dko"> Miroslav Kročko</a>, <a href="https://publications.waset.org/abstracts/search?q=Viera%20Duckov%C3%A1"> Viera Ducková</a>, <a href="https://publications.waset.org/abstracts/search?q=Vladim%C3%ADra%20K%C5%88azovick%C3%A1"> Vladimíra Kňazovická</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the study was to test the milk samples in terms of enterococci presence and their counts. Tested samples were as follows: raw cow milk, raw cow milk stored at 10°C for 16 hours and milk pasteurised at 72°C for 15 seconds. The typical colonies were isolated randomly and identified by classical biochemical test - EN-COCCUS test (Lachema, CR) and by PCR. Isolated strains were tested in terms of antibiotic resistance by well diffusion method. Examined antibiotics were: vancomycin (30 μg/disc), gentamicin (120 μg/disc), erythromycin (15 μg/disc), teicoplanine (30 μg/disc), ampicillin (10 μg/disc) and tetracycline (30 μg/disc). Average value of enterococci counts in raw milk cistern samples (n=30) was 8.25 ± 1.37 ×103 CFU/cm3. Storage tank milk samples (n=30) showed an increase (P > 0.05) and average value was 9.16 ± 1.49 × 103 CFU/cm3. Occurrence of enterococci in pasteurized milk (n=30) was sporadic and their counts were mostly below 10 CFU/cm3. Overall, 96 enterococci strains were isolated. In samples of raw cow milk and stored raw cow milk, Enterococcus faecalis was a dominant species (58.1% and 71.7%, respectively), followed by E. faecium (16.3% and 0%, respectively). Enterococcus mundtii, E. casseliflavus, E. durans and E. gallinarum were isolated, too. Resistances to ampicillin, erythromycin, gentamicin, tetracycline and vancomycin were found in 7.29%, 3.13%, 4.00%, 13.54% and 10.42% of isolated enterococci strains, respectively. Resistance to teicoplanine was not found in any isolated strain. All Vancomycin-Resistant Enterococci (VRE) belonged to E. faecalis. Obtained results confirmed that raw milk is a potential risk of enterococci resistant to antibiotics transmission into the food chain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antibiotic%20resistance" title="antibiotic resistance">antibiotic resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=enterococci" title=" enterococci"> enterococci</a>, <a href="https://publications.waset.org/abstracts/search?q=milk" title=" milk"> milk</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/5156/antibiotic-resistance-of-enterococci-isolated-from-raw-cow-milk" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/5156.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">381</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3028</span> THRAP2 Gene Identified as a Candidate Susceptibility Gene of Thyroid Autoimmune Diseases Pedigree in Tunisian Population</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ghazi%20Chabchoub">Ghazi Chabchoub</a>, <a href="https://publications.waset.org/abstracts/search?q=Mouna%20Feki"> Mouna Feki</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20Abid"> Mohamed Abid</a>, <a href="https://publications.waset.org/abstracts/search?q=Hammadi%20Ayadi"> Hammadi Ayadi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Autoimmune thyroid diseases (AITDs), including Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), are inherited as complex traits. Genetic factors associated with AITDs have been tentatively identified by candidate gene and genome scanning approaches. We analysed three intragenic microsatellite markers in the thyroid hormone receptor associated protein 2 gene (THRAP2), mapped near D12S79 marker, which have a potential role in immune function and inflammation [THRAP2-1(TG)n, THRAP2-2 (AC)n and THRAP2-3 (AC)n]. Our study population concerned 12 patients affected with AITDs belonging to a multiplex Tunisian family with high prevalence of AITDs. Fluorescent genotyping was carried out on ABI 3100 sequencers (Applied Biosystems USA) with the use of GENESCAN for semi-automated fragment sizing and GENOTYPER peak-calling software. Statistical analysis was performed using the non parametric Lod score (NPL) by Merlin software. Merlin outputs non-parametric NPLall (Z) and LOD scores and their corresponding asymptotic P values. The analysis for three intragenic markers in the THRAP2 gene revealed strong evidence for linkage (NPL=3.68, P=0.00012). Our results suggested the possible role of THRAP2 gene in AITDs susceptibility in this family. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=autoimmunity" title="autoimmunity">autoimmunity</a>, <a href="https://publications.waset.org/abstracts/search?q=autoimmune%20disease" title=" autoimmune disease"> autoimmune disease</a>, <a href="https://publications.waset.org/abstracts/search?q=genetic" title=" genetic"> genetic</a>, <a href="https://publications.waset.org/abstracts/search?q=linkage%20analysis" title=" linkage analysis"> linkage analysis</a> </p> <a href="https://publications.waset.org/abstracts/113119/thrap2-gene-identified-as-a-candidate-susceptibility-gene-of-thyroid-autoimmune-diseases-pedigree-in-tunisian-population" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/113119.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">126</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3027</span> Upconversion Nanoparticles for Imaging and Controlled Photothermal Release of Anticancer Drug in Breast Cancer</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rishav%20Shrestha">Rishav Shrestha</a>, <a href="https://publications.waset.org/abstracts/search?q=Yong%20Zhang"> Yong Zhang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Anti-Stoke upconversion process has been used extensively for bioimaging and is recently being used for photoactivated therapy in cancer utilizing upconversion nanoparticles (UCNs). The UCNs have an excitation band at 980nm; 980nm laser excitation used to produce UV/Visible emissions also produce a heating effect. Light-to-heat conversion has been observed in nanoparticles(NPs) doped with neodymium(Nd) or ytterbium(Yb)/erbium(Er) ions. Despite laser-induced heating in Rare-earth doped NPs being proven to be a relatively efficient process, only few attempts to use them as photothermal agents in biosystems have been made up to now. Gold nanoparticles and carbon nanotubes are the most researched and developed for photothermal applications. Both have large heating efficiency and outstanding biocompatibility. However, they show weak fluorescence which makes them harder to track in vivo. In that regard, UCNs are attractive due to their excellent optical features in addition to their light-to-heat conversion and excitation by NIR, for imaging and spatiotemporally releasing drugs. In this work, we have utilized a simple method to coat Nd doped UCNs with thermoresponsive polymer PNIPAM on which 4-Hydroxytamoxifen (4-OH-T) is loaded. Such UCNs demonstrate a high loading efficiency and low leakage of 4-OH-T. Encouragingly, the release of 4-OH-T can be modulated by varying the power and duration of the NIR. Such UCNs were then used to demonstrate imaging and controlled photothermal release of 4-OH-T in MCF-7 breast cancer cells. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cancer%20therapy" title="cancer therapy">cancer therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=controlled%20release" title=" controlled release"> controlled release</a>, <a href="https://publications.waset.org/abstracts/search?q=photothermal%20release" title=" photothermal release"> photothermal release</a>, <a href="https://publications.waset.org/abstracts/search?q=upconversion%20nanoparticles" title=" upconversion nanoparticles"> upconversion nanoparticles</a> </p> <a href="https://publications.waset.org/abstracts/24020/upconversion-nanoparticles-for-imaging-and-controlled-photothermal-release-of-anticancer-drug-in-breast-cancer" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24020.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">422</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3026</span> Microorganisms in Fresh and Stored Bee Pollen Originated from Slovakia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vladim%C3%ADra%20K%C5%88azovick%C3%A1">Vladimíra Kňazovická</a>, <a href="https://publications.waset.org/abstracts/search?q=M%C3%A1ria%20Dovi%C4%8Di%C4%8Dov%C3%A1"> Mária Dovičičová</a>, <a href="https://publications.waset.org/abstracts/search?q=Miroslava%20Ka%C4%8D%C3%A1niov%C3%A1"> Miroslava Kačániová</a>, <a href="https://publications.waset.org/abstracts/search?q=Margita%20%C4%8Canigov%C3%A1"> Margita Čanigová</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of the study was to test the storage of bee pollen at room temperature and in cold store, and to describe microorganisms originated from it. Fresh bee pollen originating in West Slovakia was collected in May 2010. It was tested for presence of particular microbial groups using dilution plating method, and divided into two parts with different storage (in cold store and at room temperature). Microbial analyses of pollen were repeated after one year of storage. Several bacterial strains were isolated and tested using Gram staining, for catalase and fructose-6-phosphate-phosphoketolase presence, and by rapid ID 32A (BioMérieux, France). Micromycetes were identified at genus level. Fresh pollen contained coliform bacteria, which were not detected after one year of storage in both ways. Total plate count (TPC) of aerobes and anaerobes and of yeasts in fresh bee pollen exceeded 5.00 log CFU/g. TPC of aerobes and anaerobes decreased below 2.00 log CFU/g after one year of storage in both ways. Count of yeasts decreased to 2.32 log CFU/g (at room temperature) and to 3.66 log CFU/g (in cold store). Microscopic filamentous fungi decreased from 3.41 log CFU/g (fresh bee pollen) to 1.13 log CFU/g (at room temperature) and to 1.89 log CFU/g (in cold store). In fresh bee pollen, 12 genera of micromycetes were identified in the following order according to their relative density: Penicillium > Mucor > Absidia > Cladosporium, Fusarium > Alternaria > Eurotium > Aspergillus, Rhizopus > Emericella > Arthrinium and Mycelium sterilium. After one year at room temperature, only three genera were detected in bee pollen (Penicillium > Aspergillus, Mucor) and after one year in cold store, seven genera were detected (Mucor > Penicillium, Emericella > Aspergillus, Absidia > Arthrinium, Eurotium). From the plates designated for anaerobes, eight colonies originating in fresh bee pollen were isolated. Among them, a single yeast isolate occurred. Other isolates were G+ bacteria, with a total of five rod shaped. In three out of these five, catalase was absent and fructose-6-phosphate-phosphoketolase was present. Bacterial isolates originating in fresh pollen belonged probably to genus Bifidobacterium or relative genera, but their identity was not confirmed unequivocally. In general, cold conditions are suitable for maintaining the natural properties of foodstuffs for a longer time. Slight decrease of microscopic fungal number and diversity was recorded in cold temperatures compared with storage at room temperature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bacteria" title="bacteria">bacteria</a>, <a href="https://publications.waset.org/abstracts/search?q=bee%20product" title=" bee product"> bee product</a>, <a href="https://publications.waset.org/abstracts/search?q=microscopic%20fungi" title=" microscopic fungi"> microscopic fungi</a>, <a href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering" title=" biosystems engineering"> biosystems engineering</a> </p> <a href="https://publications.waset.org/abstracts/5155/microorganisms-in-fresh-and-stored-bee-pollen-originated-from-slovakia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/5155.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">343</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3025</span> Prevalence of SARS-CoV-2 Infection and Associated Risk Factors in Selected Health Facilities of Tigray, Ethiopia: Cross-Sectional Study Design, 2023</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Weldegerima%20Gebremedhin%20Hagos">Weldegerima Gebremedhin Hagos</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The Coronavirus disease of 2019 (COVID-19) is a catastrophic emerging global health threat caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). COVID-19 has a wide range of complications and sequels. It is devastating in developing countries, causing serious health and socioeconomic crises as a result of the increasingly overburdened healthcare system. Ethiopia reported the first case of SARS-CoV-2 on 13th March 2020, with community transmission ensuing by mid-May. The aim of this study was conducted to determine the prevalence of SARS-CoV-2 infection in Tigray, Ethiopia. Methods: Facility-based correctional study designs were used on a total of 380 study participants from March 2023 up to May 2023 in two general hospitals and one comprehensive specialized hospital in Tigray, Ethiopia. A pre-structured questionnaire was used to assess information regarding the socio-demographic, clinical data and other risk factors. A nasal swap was taken by trained health professionals, and the laboratory analysis was done by RT-PCR (quant studio 7-flex, applied biosystems) in Tigrai Health Research Institute and Mekelle University Medical Microbiology Research Laboratory. Result: The mean age of the study participants was 31 (SD+/-3.5) years, with 65% being male and 35% female. The overall seropositivity of sars-cov-2 among the study participants was 5.5%. The prevalence was higher in males (6.2%) than females which were (4.7%). Sars-cov-2 infection was significantly associated with a history of lack of vaccination (p-value 0.002). There was no significant association between seropositivity and demographic factors (P > 0.05). Conclusion: The seroprevalence of SARS-CoV-2 among the study participants is high. Those study participants with a previous history of vaccination have a low probability of developing COVID-19 infection. A low SARS-CoV-2 infection rate was recorded in those who frequently use masks. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=prevalence" title="prevalence">prevalence</a>, <a href="https://publications.waset.org/abstracts/search?q=SARS-CoV-2" title=" SARS-CoV-2"> SARS-CoV-2</a>, <a href="https://publications.waset.org/abstracts/search?q=infection" title=" infection"> infection</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20factors" title=" risk factors"> risk factors</a> </p> <a href="https://publications.waset.org/abstracts/183230/prevalence-of-sars-cov-2-infection-and-associated-risk-factors-in-selected-health-facilities-of-tigray-ethiopia-cross-sectional-study-design-2023" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183230.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">55</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3024</span> Analysis of ZBTB17 Gene rs10927875 Polymorphism in Relation to Dilated Cardiomyopathy in Slovak Population</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Boro%C5%88ov%C3%A1">I. Boroňová</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Bernasovsk%C3%A1"> J. Bernasovská</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Kmec"> J. Kmec</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Petrej%C4%8D%C3%ADkov%C3%A1"> E. Petrejčíková</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Dilated cardiomyopathy (DCM) is a primary myocardial disease, it is characterized by progressive systolic dysfunction due to cardiac chamber dilatation and inefficient myocardial contractility with estimated prevalence of 37 in 100 000 people. It is the most frequent cause of heart failure and cardiac transplantation in young adults. About one-third of all patients have a suspected familial disease indicating a genetic basis of DCM. Many candidate gene studies in humans have tested the association of single nucleotide polymorphisms (SNPs) in various genes coding for proteins with a known cardiovascular function. In our study we present the results of ZBTB17 gene rs10927875 polymorphism genotyping in relation to dilated cardiomyopathy in Slovak population. The study included 78 individuals, 39 patients with DCM and 39 healthy control persons. The mean age of patients with DCM was 50.7±11.5 years; the mean age of individuals in control group was 51.3±9.8 years. Risk factors detected at baseline in each group included age, sex, body mass index, smoking status, diabetes and blood pressure. Genomic DNA was extracted from leukocytes by a standard methodology and screened for rs10927875 polymorphism in intron of ZBTB17 gene using Real-time PCR method (Step One Applied Biosystems). The distribution of investigated genotypes for rs10927875 polymorphism in the group of patients with DCM was as follows: CC (89.74%), CT (10.26%), TT (0%), and the distribution in the control group: CC (92.31%), CT (5.13%), and TT (2.56%). Using the chi-square (χ2) test we compared genotype and allele frequencies between patients and controls. There was no difference in genotype or allele frequencies in ZBTB17 gene rs10927875 polymorphism between patients and control group (χ2=3.028, p=0.220; χ2=0.264, p=0.608). Our results represent an initial study, it can be considered as preliminary and first of its kind in Slovak population. Further studies of ZBTB17 gene polymorphisms of more numerous files and additional functional investigations are needed to fully understand the role of genetic associations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dilated%20cardiomyopathy" title="dilated cardiomyopathy">dilated cardiomyopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=SNP%20polymorphism" title=" SNP polymorphism"> SNP polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=ZBTB17%20gene" title=" ZBTB17 gene"> ZBTB17 gene</a>, <a href="https://publications.waset.org/abstracts/search?q=bioscience" title=" bioscience"> bioscience</a> </p> <a href="https://publications.waset.org/abstracts/1284/analysis-of-zbtb17-gene-rs10927875-polymorphism-in-relation-to-dilated-cardiomyopathy-in-slovak-population" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1284.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">383</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3023</span> Molecular Modeling and Prediction of the Physicochemical Properties of Polyols in Aqueous Solution</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maria%20Fontenele">Maria Fontenele</a>, <a href="https://publications.waset.org/abstracts/search?q=Claude-Gilles%20Dussap"> Claude-Gilles Dussap</a>, <a href="https://publications.waset.org/abstracts/search?q=Vincent%20Dumouilla"> Vincent Dumouilla</a>, <a href="https://publications.waset.org/abstracts/search?q=Baptiste%20Boit"> Baptiste Boit</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Roquette Frères is a producer of plant-based ingredients that employs many processes to extract relevant molecules and often transforms them through chemical and physical processes to create desired ingredients with specific functionalities. In this context, Roquette encounters numerous multi-component complex systems in their processes, including fibers, proteins, and carbohydrates, in an aqueous environment. To develop, control, and optimize both new and old processes, Roquette aims to develop new in silico tools. Currently, Roquette uses process modelling tools which include specific thermodynamic models and is willing to develop computational methodologies such as molecular dynamics simulations to gain insights into the complex interactions in such complex media, and especially hydrogen bonding interactions. The issue at hand concerns aqueous mixtures of polyols with high dry matter content. The polyols mannitol and sorbitol molecules are diastereoisomers that have nearly identical chemical structures but very different physicochemical properties: for example, the solubility of sorbitol in water is 2.5 kg/kg of water, while mannitol has a solubility of 0.25 kg/kg of water at 25°C. Therefore, predicting liquid-solid equilibrium properties in this case requires sophisticated solution models that cannot be based solely on chemical group contributions, knowing that for mannitol and sorbitol, the chemical constitutive groups are the same. Recognizing the significance of solvation phenomena in polyols, the GePEB (Chemical Engineering, Applied Thermodynamics, and Biosystems) team at Institut Pascal has developed the COSMO-UCA model, which has the structural advantage of using quantum mechanics tools to predict formation and phase equilibrium properties. In this work, we use molecular dynamics simulations to elucidate the behavior of polyols in aqueous solution. Specifically, we employ simulations to compute essential metrics such as radial distribution functions and hydrogen bond autocorrelation functions. Our findings illuminate a fundamental contrast: sorbitol and mannitol exhibit disparate hydrogen bond lifetimes within aqueous environments. This observation serves as a cornerstone in elucidating the divergent physicochemical properties inherent to each compound, shedding light on the nuanced interplay between their molecular structures and water interactions. We also present a methodology to predict the physicochemical properties of complex solutions, taking as sole input the three-dimensional structure of the molecules in the medium. Finally, by developing knowledge models, we represent some physicochemical properties of aqueous solutions of sorbitol and mannitol. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=COSMO%20models" title="COSMO models">COSMO models</a>, <a href="https://publications.waset.org/abstracts/search?q=hydrogen%20bond" title=" hydrogen bond"> hydrogen bond</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20dynamics" title=" molecular dynamics"> molecular dynamics</a>, <a href="https://publications.waset.org/abstracts/search?q=thermodynamics" title=" thermodynamics"> thermodynamics</a> </p> <a href="https://publications.waset.org/abstracts/185842/molecular-modeling-and-prediction-of-the-physicochemical-properties-of-polyols-in-aqueous-solution" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185842.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">42</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3022</span> Adaptation of Requirement Engineering Practices in Pakistan</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Waqas%20Ali">Waqas Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadeem%20Majeed"> Nadeem Majeed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Requirement engineering is an essence of software development life cycle. The more time we spend on requirement engineering, higher the probability of success. Effective requirement engineering ensures and predicts successful software product. This paper presents the adaptation of requirement engineering practices in small and medium size companies of Pakistan. The study is conducted by questionnaires to show how much of requirement engineering models and practices are followed in Pakistan. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=requirement%20engineering" title="requirement engineering">requirement engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=Pakistan" title=" Pakistan"> Pakistan</a>, <a href="https://publications.waset.org/abstracts/search?q=models" title=" models"> models</a>, <a href="https://publications.waset.org/abstracts/search?q=practices" title=" practices"> practices</a>, <a href="https://publications.waset.org/abstracts/search?q=organizations" title=" organizations"> organizations</a> </p> <a href="https://publications.waset.org/abstracts/1641/adaptation-of-requirement-engineering-practices-in-pakistan" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1641.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">719</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3021</span> Case of an Engineering Design Class in Architectural Engineering</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Myunghoun%20Jang">Myunghoun Jang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Most engineering colleges in South Korea have engineering design classes in order to develop and enhance a student's creativity and problem-solving ability. Many cases about engineering design class are shown in journals and magazines, but a case lasting many years is few. The engineering design class in the Department of Architectural Engineering, Jeju National University was open in 2009 and continues to this year. 3-5 teams in every year set up their problems found their solutions and produced good results. Three of the results obtained patents. The class also provides students with opportunities to improve communication skill because they have many discussions in solving their problems. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=engineering%20design" title="engineering design">engineering design</a>, <a href="https://publications.waset.org/abstracts/search?q=architectural%20engineering" title=" architectural engineering"> architectural engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=team-based%20learning" title=" team-based learning"> team-based learning</a>, <a href="https://publications.waset.org/abstracts/search?q=construction%20safety" title=" construction safety"> construction safety</a> </p> <a href="https://publications.waset.org/abstracts/84485/case-of-an-engineering-design-class-in-architectural-engineering" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/84485.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">236</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3020</span> Multivariate Analysis of Students’ Performance in Math Courses and Specific Engineering Courses</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Naccache">H. Naccache</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Hleiss"> R. Hleiss</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The aim of this research is to study the relationship between the performance of engineering students in different math courses and their performance in specific engineering courses. The considered courses are taken mainly by engineering students during the first two years of their major. Several factors are being studied, such as gender and final grades in the math and specific engineering courses. Participants of this study comprised a sample of more than thousands of engineering students at Lebanese University during their tertiary academic years. A significant relationship tends to appear between these factors and the performance of students in engineering courses. Moreover, female students appear to outperform their male counterparts in both the math and engineering courses, and a high correlation was found between their grades in math courses and their grades in specific engineering courses. The results and implications of the study were being discussed. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=education" title="education">education</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering" title=" engineering"> engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=math" title=" math"> math</a>, <a href="https://publications.waset.org/abstracts/search?q=performance" title=" performance"> performance</a> </p> <a href="https://publications.waset.org/abstracts/39456/multivariate-analysis-of-students-performance-in-math-courses-and-specific-engineering-courses" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39456.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">340</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3019</span> Anticancer Study of Copper and Zinc Complexes with Doxorubicin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Grzegorz%20Swiderski">Grzegorz Swiderski</a>, <a href="https://publications.waset.org/abstracts/search?q=Agata%20Jablonska-Trypuc"> Agata Jablonska-Trypuc</a>, <a href="https://publications.waset.org/abstracts/search?q=Natalia%20Popow"> Natalia Popow</a>, <a href="https://publications.waset.org/abstracts/search?q=Renata%20Swislocka"> Renata Swislocka</a>, <a href="https://publications.waset.org/abstracts/search?q=Wlodzimierz%20Lewandowski"> Wlodzimierz Lewandowski</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Doxorubicin belongs to the group of anthracycline antitumor antibiotics. Because of the wide spectrum of actions, it is one of the most widely used anthracycline antibiotics, including the treatment of breast, ovary, bladder, lung cancers as well as neuroblastoma, lymphoma, leukemia and myeloid leukemia. Antitumor activity of doxorubicin is based on the same mechanisms as for most anthracyclines. Like the metal ions affect the nucleic acids on many biological processes, so the environment of the metal chelates of antibiotics can have a significant effect on the pharmacological properties of drugs. Complexation of anthracyclines with metal ions may contribute to the production of less toxic compounds. In the framework of this study, the composition of complexes obtained in aqueous solutions of doxorubicin with metal ions (Cu2+ and Zn2+). Complexation was analyzed by spectrophotometric titration in aqueous solution at pH 7.0. The pH was adjusted with 0.02M Tris-HCl buffer. The composition of the complexes found was Cu: doxorubicin (1: 2) and a Zn: doxorubicin (1: 1). The effect of Dox, Dox-Cu and Dox-Zn was examined in MCF-7 breast cancer cell line, which were obtained from American Type Culture Collection (ATCC). The compounds were added to the cultured cells for a final concentration in the range of 0,01µM to 0,5µM. The number of MCF-7 cells with division into living and dead, was determined by direct counts of cells with the use of trypan blue dye using LUNA Logos Biosystems cell counter. ApoTox-Glo Triplex Assay (Promega, Madison, Wisconsin, USA) was used according to the manufacturer’s instructions to measure the MCF-7 cells’ viability, cytotoxicity and apoptosis. We observed a decrease in cells proliferation in a dose-dependent manner. An increase in cytotoxicity and decrease in viability in the ApoTox Triplex assay was also showed for all tested compounds. Apoptosis, showed as caspase 3/7 activation, was observed only in Dox treatment. In Dox-Zn and Dox-Cu caspase 3/7 activation was not observed. This work was financially supported by National Science Centre, Poland, under the research project number 2014/13/B/NZ7/02 352. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anticancer%20properties" title="anticancer properties">anticancer properties</a>, <a href="https://publications.waset.org/abstracts/search?q=anthracycline%20antibiotic" title=" anthracycline antibiotic"> anthracycline antibiotic</a>, <a href="https://publications.waset.org/abstracts/search?q=doxorubicine" title=" doxorubicine"> doxorubicine</a>, <a href="https://publications.waset.org/abstracts/search?q=metal%20complexes" title=" metal complexes"> metal complexes</a> </p> <a href="https://publications.waset.org/abstracts/63652/anticancer-study-of-copper-and-zinc-complexes-with-doxorubicin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/63652.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">280</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3018</span> Geotechnical Engineering Solutions for Adaptation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Johnstone%20Walubengo%20Wangusi">Johnstone Walubengo Wangusi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Geotechnical engineering is a multidisciplinary field that encompasses the study of soil, rock, and groundwater properties and their interactions with civil engineering structures. This research paper provides an in-depth overview of geotechnical engineering, covering its fundamental principles, applications in civil infrastructure projects, and the challenges faced by practitioners in the field. Through a comprehensive examination of soil mechanics, foundation design, slope stability analysis, and geotechnical site investigation techniques, this paper aims to highlight the importance of geotechnical engineering in ensuring the safety, stability, and sustainability of infrastructure development. Additionally, it discusses emerging trends, innovative technologies, and future directions in geotechnical engineering research and practice. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sustainable%20geotechnical%20engineering%20solutions" title="sustainable geotechnical engineering solutions">sustainable geotechnical engineering solutions</a>, <a href="https://publications.waset.org/abstracts/search?q=education%20and%20training%20for%20future%20generations%20geotechnical%20engineers" title=" education and training for future generations geotechnical engineers"> education and training for future generations geotechnical engineers</a>, <a href="https://publications.waset.org/abstracts/search?q=integration%20of%20geotechnical%20engineering%20and%20structural%20engineering" title=" integration of geotechnical engineering and structural engineering"> integration of geotechnical engineering and structural engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=use%20of%20AI%20in%20geotechnical%20engineering%20modelling" title=" use of AI in geotechnical engineering modelling"> use of AI in geotechnical engineering modelling</a> </p> <a href="https://publications.waset.org/abstracts/184517/geotechnical-engineering-solutions-for-adaptation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184517.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">59</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3017</span> Attribute Selection for Preference Functions in Engineering Design</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ali%20E.%20Abbas">Ali E. Abbas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Industrial Engineering is a broad multidisciplinary field with intersections and applications in numerous areas. When designing a product, it is important to determine the appropriate attributes of value and the preference function for which the product is optimized. This paper provides some guidelines on appropriate selection of attributes for preference and value functions for engineering design. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=decision%20analysis" title="decision analysis">decision analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=industrial%20engineering" title=" industrial engineering"> industrial engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=direct%20vs.%20indirect%20values" title=" direct vs. indirect values"> direct vs. indirect values</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering%20management" title=" engineering management"> engineering management</a> </p> <a href="https://publications.waset.org/abstracts/50987/attribute-selection-for-preference-functions-in-engineering-design" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/50987.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">306</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3016</span> Experiential Learning in an Earthquake Engineering Course Using Online Tools and Shake Table Exercises</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Andres%20Winston%20Oreta">Andres Winston Oreta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Experiential Learning (ELE) is a strategy for enhancing the teaching and learning of courses especially in civil engineering. This paper presents the adaption of the ELE framework in the delivery of various course requirements in an earthquake engineering course. Examples of how ELE is integrated using online tools and hands-on laboratory technology to address the course learning outcomes on earthquake engineering are presented. Student feedback shows that ELE using online tools and technology strengthens students’ understanding and intuition of seismic design and earthquake engineering concepts. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=earthquake%20engineering" title="earthquake engineering">earthquake engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=experiential%20learning" title=" experiential learning"> experiential learning</a>, <a href="https://publications.waset.org/abstracts/search?q=shake%20table" title=" shake table"> shake table</a>, <a href="https://publications.waset.org/abstracts/search?q=online" title=" online"> online</a>, <a href="https://publications.waset.org/abstracts/search?q=internet" title=" internet"> internet</a>, <a href="https://publications.waset.org/abstracts/search?q=civil%20engineering" title=" civil engineering"> civil engineering</a> </p> <a href="https://publications.waset.org/abstracts/189318/experiential-learning-in-an-earthquake-engineering-course-using-online-tools-and-shake-table-exercises" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/189318.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">22</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3015</span> Expression of miRNA 335 in Gall Bladder Cancer: A Correlative Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Naseem%20Fatima">Naseem Fatima</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20N.%20Srivastava"> A. N. Srivastava</a>, <a href="https://publications.waset.org/abstracts/search?q=Tasleem%20Raza"> Tasleem Raza</a>, <a href="https://publications.waset.org/abstracts/search?q=Vijay%20Kumar"> Vijay Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Carcinoma gallbladder is third most common gastrointestinal lethal disease with the highest incidence and mortality rate among women in Northern India. Scientists have found several risk factors that make a person more likely to develop gallbladder cancer; among these risk factors, deregulation of miRNAs has been demonstrated to be one of the most crucial factors. The changes in the expression of specific miRNA genes result in the control of inflammation, cell cycle regulation, stress response, proliferation, differentiation, apoptosis and invasion thus mediate the process in tumorgenesis. The aim of this study was to investigate the role of MiRNA-335 and may as a molecular marker in early detection of gallbladder cancer in suspected cases. Material and Methods: A total of 20 consecutive patients with gallbladder cancer aged between 30-75 years were registered for the study. Total RNA was extracted from tissue by using the mirVANA MiRNA isolation Kit according to the manufacturer’s protocol. The MiRNA- 335 and U6 snRNA-specific cDNA were reverse-transcribed from total RNA using Taqman microRNA reverse-transcription kit according to the manufacturer’s protocol. TaqMan MiRNA probes hsa-miR-335 and Taqman Master Mix without AmpEase UNG, Individual real-time PCR assays were performed in a 20 μL reaction volume on a Real-Time PCR system (Applied Biosystems StepOnePlus™) to detect MiRNA-335 expression in tissue. Relative quantification of target MiRNA expression was evaluated using the comparative cycle threshold (CT) method. The correlation was done in between cycle threshold (CT Value) of target MiRNA in gallbladder cancer with respect to non-cancerous Cholelithiasis gallbladder. Each sample was examined in triplicate. The Newman-Keuls Multiple Comparison Test was used to determine the expression of miR-335. Results: MiRNA335 was found to be significantly downregulated in the gallbladder cancer tissue (P<0.001), when compared with non-cancerous Cholelithiasis gallbladder cases. Out of 20 cases, 75% showed reduced expression of MiRNA335, were at last stage of disease with low overall survival rate and remaining 25% were showed up-regulated expression of MiRNA335 with high survival rate. Conclusion: The present study showed that reduced expression of MiRNA335 is associated with the advancement of the disease, and its deregulation may provide important clues to understanding it as a prognostic marker and opportunities for future research. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carcinoma%20gallbladder" title="carcinoma gallbladder">carcinoma gallbladder</a>, <a href="https://publications.waset.org/abstracts/search?q=downregulation" title=" downregulation"> downregulation</a>, <a href="https://publications.waset.org/abstracts/search?q=MiRNA-335" title=" MiRNA-335"> MiRNA-335</a>, <a href="https://publications.waset.org/abstracts/search?q=RT-PCR%20assay" title=" RT-PCR assay"> RT-PCR assay</a> </p> <a href="https://publications.waset.org/abstracts/46961/expression-of-mirna-335-in-gall-bladder-cancer-a-correlative-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46961.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">360</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3014</span> Engineering Practice in Nigerian University: A Microcosm of Engineering Development and Practice in Developing Countries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sunday%20Olufemi%20Adesogan">Sunday Olufemi Adesogan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There is a strong link between engineering and development. Engineering as a profession is a call to service by the society. Perhaps next to soldiers, engineers are the most patriotic professionals. However, unlike soldiers, they remain servants of society at all times and in all circumstances. Despite their role to the society, engineering profession seems not to be enjoying the respect due to it probably because of failures associated with some engineering projects. This paper focuses on the need to improve on engineering practices for developments in developing countries using Engineering practice in Nigerian Universities as a tool for argument. Purposeful Survey, interview and focus group discussion were carried out among one hundred and twenty (120) reputable firms in Nigeria. The topic was approached through a few projects that the firms have been involved in from the planning stage, some to completion and beyond into the stage of maintenance and monitoring. It is revealed that some factors which are not determined by the engineers themselves impeded progress and full success of engineering practice in developing countries. The key culprit is corruption whose eradication will put the nation on the solid path of effective engineering development and poverty alleviation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=development" title="development">development</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering" title=" engineering"> engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=practices" title=" practices"> practices</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainable" title=" sustainable"> sustainable</a> </p> <a href="https://publications.waset.org/abstracts/66490/engineering-practice-in-nigerian-university-a-microcosm-of-engineering-development-and-practice-in-developing-countries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66490.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">333</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3013</span> Software Engineering Revolution Driven by Complexity Science</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jay%20Xiong">Jay Xiong</a>, <a href="https://publications.waset.org/abstracts/search?q=Li%20Lin"> Li Lin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper introduces a new software engineering paradigm based on complexity science, called NSE (Nonlinear Software Engineering paradigm). The purpose of establishing NSE is to help software development organizations double their productivity, half their cost, and increase the quality of their products in several orders of magnitude simultaneously. NSE complies with the essential principles of complexity science. NSE brings revolutionary changes to almost all aspects in software engineering. NSE has been fully implemented with its support platform Panorama++. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=complexity%20science" title="complexity science">complexity science</a>, <a href="https://publications.waset.org/abstracts/search?q=software%20development" title=" software development"> software development</a>, <a href="https://publications.waset.org/abstracts/search?q=software%20engineering" title=" software engineering"> software engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=software%20maintenance" title=" software maintenance"> software maintenance</a> </p> <a href="https://publications.waset.org/abstracts/41084/software-engineering-revolution-driven-by-complexity-science" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41084.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">265</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3012</span> A New Profile of Engineer: From Management Engineering to Entrepreneurial Engineering</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Roberto%20Cerchione">Roberto Cerchione</a>, <a href="https://publications.waset.org/abstracts/search?q=Emilio%20Esposito"> Emilio Esposito</a>, <a href="https://publications.waset.org/abstracts/search?q=Mario%20Raffa"> Mario Raffa</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The relevance and the strategic importance of engineering skills in innovation and in the development of businesses and organizations push to investigate the role of the engineer in society today. In the twentieth century the emergence of a variety of technical and scientific knowledge has led to the rise of new areas of skills going from a "all-comprehensive" engineering to an engineering characterized by many specializations. Organizational and structural changes within companies and the emergence of an industrial society based on multiple interrelationships led to the transformation of engineering education. The objective of this work is to report main steps and many pioneering experiences, both national and international, that have led to establish a graduate degree program in Engineering Management and its subsequent evolution in Entrepreneurial Engineering. The first section of this article focuses on the origins and precursors of Engineering Management education. The second section concerns main Italian education programs. Then the attention is focused on the evolution of Engineering Management in Naples, on the intersectoral nature of this degree program, on the relationship with business community, associations, labor market, small businesses and environment. Finally, the discussion of recent years about the skills that characterize entrepreneurial engineer in society are presented. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=education" title="education">education</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering%20management" title=" engineering management"> engineering management</a>, <a href="https://publications.waset.org/abstracts/search?q=entrepreunerial%20engineering" title=" entrepreunerial engineering"> entrepreunerial engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering%20skills" title=" engineering skills"> engineering skills</a>, <a href="https://publications.waset.org/abstracts/search?q=managerial%20skills" title=" managerial skills"> managerial skills</a>, <a href="https://publications.waset.org/abstracts/search?q=entrepreneurial%20skills" title=" entrepreneurial skills"> entrepreneurial skills</a> </p> <a href="https://publications.waset.org/abstracts/18102/a-new-profile-of-engineer-from-management-engineering-to-entrepreneurial-engineering" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18102.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">487</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3011</span> The Effect of Engineering Construction in Online Consultancy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mariam%20Wagih%20Nagib%20Eskandar">Mariam Wagih Nagib Eskandar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The engineering design process is the activities formulation, to help an engineer raising a plan with a specified goal and performance. The engineering design process is a multi-stage course of action including the conceptualization, research, feasibility studies, establishment of design parameters, preliminary and finally the detailed design. It is a progression from the abstract to the concrete; starting with probably abstract ideas about need, and thereafter elaborating detailed specifications of the object that would satisfy the needs, identified. Engineering design issues, problems, and solutions are discussed in this paper using qualitative approach from an information structure perspective. The objective is to identify the problems, to analyze them and propose solutions by integrating; innovation, practical experience, time and resource management, communications skills, isolating the problem in coordination with all stakeholders. Consequently, this would be beneficial for the engineering community to improve the Engineering design practices. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=education" title="education">education</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering" title=" engineering"> engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=math" title=" math"> math</a>, <a href="https://publications.waset.org/abstracts/search?q=performanceengineering%20design" title=" performanceengineering design"> performanceengineering design</a>, <a href="https://publications.waset.org/abstracts/search?q=architectural%20engineering" title=" architectural engineering"> architectural engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=team-based%20learning" title=" team-based learning"> team-based learning</a>, <a href="https://publications.waset.org/abstracts/search?q=construction%20safetyrequirement%20engineering" title=" construction safetyrequirement engineering"> construction safetyrequirement engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=models" title=" models"> models</a>, <a href="https://publications.waset.org/abstracts/search?q=practices" title=" practices"> practices</a>, <a href="https://publications.waset.org/abstracts/search?q=organizations" title=" organizations"> organizations</a> </p> <a href="https://publications.waset.org/abstracts/183787/the-effect-of-engineering-construction-in-online-consultancy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183787.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">80</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3010</span> A Qualitative Approach to Engineering Design Issues, Problems, and Solutions</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20U.%20Arshid">M. U. Arshid</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20A.%20Kamal"> M. A. Kamal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The engineering design process is the activities formulation, to help an engineer raising a plan with a specified goal and performance. The engineering design process is a multi-stage course of action including the conceptualization, research, feasibility studies, establishment of design parameters, preliminary and finally the detailed design. It is a progression from the abstract to the concrete; starting with probably abstract ideas about need, and thereafter elaborating detailed specifications of the object that would satisfy the needs, identified. Engineering design issues, problems, and solutions are discussed in this paper using qualitative approach from an information structure perspective. The objective is to identify the problems, to analyze them and propose solutions by integrating; innovation, practical experience, time and resource management, communications skills, isolating the problem in coordination with all stakeholders. Consequently, this would be beneficial for the engineering community to improve the Engineering design practices. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=engineering%20design" title="engineering design">engineering design</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering%20design%20issues" title=" engineering design issues"> engineering design issues</a>, <a href="https://publications.waset.org/abstracts/search?q=innovation" title=" innovation"> innovation</a>, <a href="https://publications.waset.org/abstracts/search?q=public%20sector%20projects" title=" public sector projects"> public sector projects</a> </p> <a href="https://publications.waset.org/abstracts/41762/a-qualitative-approach-to-engineering-design-issues-problems-and-solutions" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41762.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">346</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3009</span> STR and SNP Markers of Y-Chromosome Unveil Similarity between the Gene Pool of Kurds and Yezidis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Chukhryaeva">M. Chukhryaeva</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Skhalyakho"> R. Skhalyakho</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Kagazegeva"> J. Kagazegeva</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Pocheshkhova"> E. Pocheshkhova</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Yepiskopossyan"> L. Yepiskopossyan</a>, <a href="https://publications.waset.org/abstracts/search?q=O.%20Balanovsky"> O. Balanovsky</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20Balanovska"> E. Balanovska</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The Middle East is crossroad of different populations at different times. The Kurds are of particular interest in this region. Historical sources suggested that the origin of the Kurds is associated with Medes. Therefore, it was especially interesting to compare gene pool of Kurds with other supposed descendants of Medes-Tats. Yezidis are ethno confessional group of Kurds. Yezidism as a confessional teaching was formed in the XI-XIII centuries in Iraq. Yezidism has caused reproductively isolation of Yezidis from neighboring populations for centuries. Also, isolation helps to retain Yezidian caste system. It is unknown how the history of Yezidis affected its genу pool because it has never been the object of researching. We have examined the Y-chromosome variation in Yezidis and Kurdish males to understand their gene pool. We collected DNA samples from 90 Yezidi males and 24 Kurdish males together with their pedigrees. We performed Y-STR analysis of 17 loci in the samples collected (Yfiler system from Applied Biosystems) and analysis of 42 Y-SNPs by real-time PCR. We compared our data with published data from other Kurdish groups and from European, Caucasian, and West Asian populations. We found that gene pool of Yezidis contains haplogroups common in the Middle East (J-M172(xM67,M12)- 24%, E-M35(xM78)- 9%) and in South Western Asia (R-M124- 8%) and variant with wide distribution area - R-M198(xM458- 9%). The gene pool of Kurdish has higher genetic diversity than Yezidis. Their dominants haplogroups are R-M198- 20,3 %, E-M35- 9%, J-M172- 9%. Multidimensional scaling also shows that the Kurds and Yezidis are part of the same frontier Asian cluster, which, in addition, included Armenians, Iranians, Turks, and Greeks. At the same time, the peoples of the Caucasus and Europe form isolated clusters that do not overlap with the Asian clusters. It is noteworthy that Kurds from our study gravitate towards Tats, which indicates that most likely these two populations are descendants of ancient Medes population. Multidimensional scaling also reveals similarity between gene pool of Yezidis, Kurds with Armenians and Iranians. The analysis of Yezidis pedigrees and their STR variability did not reveal a reliable connection between genetic diversity and caste system. This indicates that the Yezidis caste system is a social division and not a biological one. Thus, we showed that, despite many years of isolation, the gene pool of Yezidis retained a common layer with the gene pool of Kurds, these populations have common spectrum of haplogroups, but Yezidis have lower genetic diversity than Kurds. This study received primary support from the RSF grant No. 16-36-00122 to MC and grant No. 16-06-00364 to EP. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=gene%20pool" title="gene pool">gene pool</a>, <a href="https://publications.waset.org/abstracts/search?q=haplogroup" title=" haplogroup"> haplogroup</a>, <a href="https://publications.waset.org/abstracts/search?q=Kurds" title=" Kurds"> Kurds</a>, <a href="https://publications.waset.org/abstracts/search?q=SNP%20and%20STR%20markers" title=" SNP and STR markers"> SNP and STR markers</a>, <a href="https://publications.waset.org/abstracts/search?q=Yezidis" title=" Yezidis"> Yezidis</a> </p> <a href="https://publications.waset.org/abstracts/82834/str-and-snp-markers-of-y-chromosome-unveil-similarity-between-the-gene-pool-of-kurds-and-yezidis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/82834.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">205</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3008</span> Research on Community-Based Engineering Learning and Undergraduate Students’ Creativity in China: The Moderate Effect of Engineering Identity</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Liang%20Wang">Liang Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Wei%20Zhang"> Wei Zhang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There have been some existing researches on design-based engineering learning (DBEL) and project-based or problem-based engineering learning (PBEL). Those findings have greatly promoted the reform of engineering education in China. However, the engineering with a big E means that more and more engineering activities are designed and operated by communities of practice (CoPs), namely community-based engineering learning. However, whether community-based engineering learning can promote students' innovation has not been verified in published articles. This study fills this gap by investigating the relationship between community-based learning approach and students’ creativity, using engineering identity as an intermediary variable. The goal of this study is to discover the core features of community-based engineering learning, and make the features more beneficial for students’ creativity. The study created and adapted open survey items from previously published studies and a scale on learning community, students’ creativity and engineering identity. Firstly, qualitative content analysis methods by MAXQDA were used to analyze 32 open-ended questionnaires. Then the authors collected data (n=322) from undergraduate students in engineering competition teams and engineering laboratories in Zhejiang University, and structural equation modelling (SEM) was used to understand the relationship between different factors. The study finds: (a) community-based engineering learning has four main elements like real-task context, self-inquiry learning, deeply-consulted cooperation and circularly-iterated design, (b) community-based engineering learning can significantly enhance the engineering undergraduate students’ creativity, and (c) engineering identity partially moderated the relationship between community-based engineering learning and undergraduate students' creativity. The findings further illustrate the value of community-based engineering learning for undergraduate students. In the future research, the authors should further clarify the core mechanism of community-based engineering learning, and pay attention to the cultivation of undergraduate students’ engineer identity in learning community. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=community-based%20engineering%20learning" title="community-based engineering learning">community-based engineering learning</a>, <a href="https://publications.waset.org/abstracts/search?q=students%27%20creativity" title=" students&#039; creativity"> students&#039; creativity</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering%20identity" title=" engineering identity"> engineering identity</a>, <a href="https://publications.waset.org/abstracts/search?q=moderate%20effect" title=" moderate effect"> moderate effect</a> </p> <a href="https://publications.waset.org/abstracts/134357/research-on-community-based-engineering-learning-and-undergraduate-students-creativity-in-china-the-moderate-effect-of-engineering-identity" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/134357.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">145</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering&amp;page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=biosystems%20engineering&amp;page=3">3</a></li> <li class="page-item"><a class="page-link" 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