ExplorEnz: EC 2.3.1.82

<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0//EN" "http://www.w3.org/TR/REC-html40/strict.dtd"> <html> <head> <title>ExplorEnz: EC 2.3.1.82</title> <meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1" /> <meta name="keywords" content="EC 2.3.1.82,ExplorEnz,IUBMB,Enzyme Nomenclature Database,Enzyme Classification" /> <meta name="description" content="Enzyme Nomenclature Database" /> <meta name="robots" content="index,nofollow"> <meta name="googlebot" content="index,nofollow" /> <link rel="stylesheet" type="text/css" href="enzyme2.css"> <link rel="shortcut icon" href="favicon.ico" /> <style type="text/css" media="screen">  </style> </head> <base href="//query.php?ec=2.3.1.82"> <body> <a href="index.php"> <img src="images/banner_5.gif" alt="The Enzyme Database" width="920 px" height="" border="0" /></a> </div><table border="0" cellborder="0" cellspacing="0" cellpadding="0" width="100%" id="nav"> <tr> <td class="f" nowrap="nowrap" colspan="1" border="0"> <li><a href="./" alt="Home" title="Home">Home</a></li> <li><a href="search.php" alt="Simple Search" title="Search the database">Search</a></li> <li><a href="class.php" alt="Enzyme Classes" title="Hierarchical view of the Enzyme Classification system">Enzymes by Class</a></li> <li><a href="newenz.php" alt="New/Modified Enzymes" title="New/modified enzyme entries">New/Amended Enzymes</a></li> <li><a href="stats.php" alt="Enzyme Count" title="Enzyme count">Statistics</a></li> <li><a href="forms.php" alt="Forms" title="Submit data on a new enzyme, or report an error">Forms</a></li> <li><a href="news.php" alt="News" title="Reports on recent developments in enzyme classification or changes to nomenclature">News</a></li> <li><a href="about.php" alt="Help Files, Archives" title="Quick-start Guide, FAQ, Supplements">Information</a></li> <li><a href="downloads.php" alt="Downloads" title="Download the database">Downloads</a></li> <li></li> </td> </tr> </table> Your query returned 1 entry.    <a href="query.php?ec=2.3.1.82&pr=on" target="new"><img src="images/print.png" alt="printer_icon" align="center" border="0"></a>Printable version <table border="0" cellpadding="2" cellspacing="3" width="100%"> <tr valign="bottom"> <td width="20%" align="right"><a name="1"></a>EC</td> <td width="80%" colspan="1">2.3.1.82     </td> </tr> <tr> <td width="20%" align="right">Accepted name:</td> <td width="80%" colspan="1">aminoglycoside 6′-N-acetyltransferase</td> </tr> <tr> <td width="20%" align="right">Reaction:</td> <td width="80%" colspan="1">acetyl-CoA + kanamycin-B = CoA + N6′-acetylkanamycin-B</td> </tr> <tr> <td width="20%" align="right">Glossary:</td> <td width="80%" colspan="1"><a target="new" href="glossary/kanamyc.html">kanamycin</a></td> </tr> <tr> <td width="20%" align="right">Other name(s):</td> <td width="80%" colspan="1">aminoglycoside N6′-acetyltransferase; aminoglycoside-6′-acetyltransferase; aminoglycoside-6-N-acetyltransferase; kanamycin acetyltransferase</td> </tr> <tr valign="top"> <td width="20%" align="right">Systematic name: </td> <td width="80%" colspan="1">acetyl-CoA:kanamycin-B N6′-acetyltransferase</td> </tr> <tr valign="top"> <td width="20%" align="right">Comments:</td> <td width="80%" colspan="1">The antibiotics kanamycin A, kanamycin B, neomycin, gentamicin C1a, gentamicin C2 and sisomicin are substrates. The antibiotic tobramycin, but not paromomycin, can also act as acceptor. The 6-amino group of the purpurosamine ring is acetylated.</td> </tr> <tr> <td width="20%" align="right">Links to other databases:</td> <td width="80%" colspan="1"><a href="https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.1.82" target="new">BRENDA</a>, <a href="https://enzyme.expasy.org/EC/2.3.1.82" target="new">EXPASY</a>, <a href="https://www.ncbi.nlm.nih.gov/gene/?term=2.3.1.82%5BEC%5D" target="new">Gene</a>, <a href="https://www.kegg.jp/dbget-bin/www_bget?ec:2.3.1.82" target="new">KEGG</a>, <a href="http://biocyc.org/META/NEW-IMAGE?type=EC-NUMBER&object=EC-2.3.1.82" target="new">MetaCyc</a>, <a href="https://www.rcsb.org/search?request=%7B%22query%22%3A%7B%22type%22%3A%22terminal%22%2C%22service%22%3A%22text%22%2C%22parameters%22%3A%7B%22attribute%22%3A%22rcsb_polymer_entity.rcsb_ec_lineage.id%22%2C%22operator%22%3A%22in%22%2C%22value%22%3A%5B%222.3.1.82%22%5D%7D%7D%2C%22return_type%22%3A%22polymer_entity%22%7D" target="new">PDB</a>, CAS registry number: 56467-65-3</td> </tr> <tr> <td width="20%" align="right" valign="top">References:</td> <td align="left" valign="top" colspan="1"> <table border="0" cellpadding="0"><tr> <td>1. </td> <td>le Goffic, F. and Martel, A. La résistance aux aminosides provoquée par une isoenzyme la kanamycine acétyltransférase. Biochimie 56 (1974) 893–897. [<a href="https://doi.org/10.1016/S0300-9084(74)80512-2" target="new">DOI</a>] [PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/4614862" target="new">4614862</a>] </td> </tr> </td></tr> <tr> <td>2. </td> <td>Benveniste, R. and Davies, J.E. Enzymatic acetylation of aminoglycoside antibiotics by Escherichia coli carrying an R factor. Biochemistry 10 (1971) 1787–1796. [PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/4935296" target="new">4935296</a>] </td> </tr> </td></tr> <tr> <td>3. </td> <td>Dowding, J.E. Mechanisms of gentamicin resistance in Staphylococcus aureus. Antimicrob. Agents Chemother. 11 (1977) 47–50. [PMID: <a href="https://pubmed.ncbi.nlm.nih.gov/836013" target="new">836013</a>] </td> </tr> </td></tr> </table></td></tr> </td></tr> <tr><td colspan="2"><center>[EC 2.3.1.82 created 1976 as EC 2.3.1.55, transferred 1999 to EC 2.3.1.82, modified 1999, modified 2015]</center></td> </tr> <tr> <td> </td> <td></td> </tr> <tr> <td> </td> <td></td> </tr> </table> <center>Data © 2001–2024 IUBMB Web site © 2005–2024 Andrew McDonald </center> </body> </html>

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ExplorEnz: EC 2.3.1.82