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<!doctype html> <html lang="ja"> <head> <title>Environmental Stressors: Is the Sperm Cell Vulnerable or Res | 14230</title> <meta name="keywords" content="Hyacinth Highland , "/> <meta name="description" content="The sperm is a unique cell, differing from other cells in physiology and function. It survives an arduous journey through male and female reproductive trac..14230"/> <meta name="citation_publisher" content="ロングダム出版SL" /> <meta name="citation_journal_title" content="アンドロロジー - オープンアクセス"> <meta name="citation_title" content="Environmental Stressors: Is the Sperm Cell Vulnerable or Resilient?"> <meta name="citation_author" content="Hyacinth Highl" /> <meta name="citation_author" content="" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="5"> <meta name="citation_issue" content="1"> <meta name="citation_abstract" content="The sperm is a unique cell, differing from other cells in physiology and function. It survives an arduous journey through male and female reproductive tracts, to ensure that an intact male genome reaches the site of fertilization. In addition, it has also been recognized to wield epigenetic control over early embryonic development. Environmental degradation over the past years has exposed the human sperm to myriads of toxicants which have adversely affected its structure and function. In correlation, there are reports of decline in sperm counts and fertility, although there is still no concrete evidence to substantiate these claims. Moreover population statistics in most developing nations do not conform to data of declining fertility. In addition there are certain researches, in agreement with our data of normal, fertile volunteers, which also suggest no change in semen characteristics or sperm numbers over the past three decades. These findings indicate that despite the barrage from environmental agents, spermatozoa have withstood the test of time and have emerged resilient. Hence, in addition to the manifold machinery that operate to protect the spermatozoa including toll-like receptors, anti-oxidants, heat shock proteins etc., there possibly exists an in-built, genetically programmed, population specific mechanism that reinforces its nuclear integrity to protect this cell from the onslaught of toxic influences. Research in this direction is underway at our laboratory and other research centers to delve into the enigma of sperm endurance. 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It survives an arduous journey through male and female reproductive tracts, to ensure that an intact male genome reaches the site of fertilization. In addition, it has also been recognized to wield epigenetic control over early embryonic development. Environmental degradation over the past years has exposed the human sperm to myriads of toxicants which have adversely affected its structure and function. In correlation, there are reports of decline in sperm counts and fertility, although there is still no concrete evidence to substantiate these claims. Moreover population statistics in most developing nations do not conform to data of declining fertility. In addition there are certain researches, in agreement with our data of normal, fertile volunteers, which also suggest no change in semen characteristics or sperm numbers over the past three decades. These findings indicate that despite the barrage from environmental agents, spermatozoa have withstood the test of time and have emerged resilient. Hence, in addition to the manifold machinery that operate to protect the spermatozoa including toll-like receptors, anti-oxidants, heat shock proteins etc., there possibly exists an in-built, genetically programmed, population specific mechanism that reinforces its nuclear integrity to protect this cell from the onslaught of toxic influences. Research in this direction is underway at our laboratory and other research centers to delve into the enigma of sperm endurance.</p> <div class="alert alert-info text-left"><b>免責事項:</b> この要約は人工知能ツールを使用して翻訳されたものであり、まだレビューまたは検証されていません。</div> <div class="nav social-icons"> <a class="nav-link w-auto">この記事をシェアする</a> <a title="ここをクリック" target="_blank" href="https://www.facebook.com/sharer.php?u=https://japanese.longdom.org/abstract/environmental-stressors-is-the-sperm-cell-vulnerable-or-resilient-14230.html" rel="noopener"><i class="fab fa-facebook-f"></i></a> <a class="nav-link" title="ここをクリック" target="_blank" href="https://twitter.com/share?url=https://japanese.longdom.org/abstract/environmental-stressors-is-the-sperm-cell-vulnerable-or-resilient-14230.html" rel="noopener"><i class="fab fa-twitter"></i></a> <a class="nav-link" title="ここをクリック" target="_blank" href="https://www.linkedin.com/shareArticle?mini=true&url=https://japanese.longdom.org/abstract/environmental-stressors-is-the-sperm-cell-vulnerable-or-resilient-14230.html" rel="noopener"><i class="fab fa-linkedin-in"></i></a> <a class="nav-link" title="ここをクリック" target="_blank" href="https://plus.google.com/share?url=https://japanese.longdom.org/abstract/environmental-stressors-is-the-sperm-cell-vulnerable-or-resilient-14230.html" rel="noopener"><i class="fab fa-google-plus-g"></i></a> </div> </div> </div> </div> </section> <footer class="bg-blue-grey-900 py-3"> <div class="container"> <div class="row"> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">コンテンツリンク</h4> <ul class="list-unstyled footer-links font-size-3"> <li><a class="" href="https://japanese.longdom.org/privacy-policy.html" title="ここをクリック">プライバシーポリシー</a></li> <li><a class="" href="https://japanese.longdom.org/terms-conditions.html" title="ここをクリック">利用規約</a></li> <li><a class="" href="https://japanese.longdom.org/authors-reviewers-editors.html" title="ここをクリック">著者、査読者、編集者</a></li> </ul> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">ロングダムに連絡する</h4> <p><strong>ロングダムグループ SA</strong><br /> ロジェ・ヴァンデンドリッシュ通り、<br /> 18、1150 ブリュッセル、ベルギー<br /> 電話番号: +442038085340<br /> <strong>メール:</strong> <a class="white" href="mailto:info@longdom.org" title="ここをクリック">info@longdom.org</a></p> </div> <div class="col-12 col-sm-4"> <h4 class="white font-size-4 fweight-400 border-bottom-1 pb-2">接続</h4> <nav class="nav nav-pills social-icons-footer flex-column a-pl-0"> <a href="https://www.facebook.com/longdompublisher" title="ここをクリック" target="_blank" class="nav-link bg-facebook-hover"><i class="fab fa-facebook-f bg-facebook"></i></a> <a href="https://www.linkedin.com/company/longdom-publishing-sl/" title="ここをクリック" target="_blank" class="nav-link bg-linkedin-hover"><i class="fab fa-linkedin-in bg-linkedin"></i></a> <a href="https://twitter.com/LongdomP" title="ここをクリック" target="_blank" class="nav-link bg-twitter-hover"><i class="fab fa-twitter bg-twitter"></i></a> <a href="https://www.instagram.com/longdom_publisher/" title="ここをクリック" target="_blank" class="nav-link bg-instagram-hover"><i class="fab fa-instagram bg-instagram"></i></a> </nav> </div> </div> <div class="row text-center"> <div class="col"> <p>著作権 © 2024 <a href="https://japanese.longdom.org/" title="ここをクリック" class="white">ロングダム出版SL</a>.</p> </div> </div> </div> </footer>  <a href="#0" class="cd-top js-cd-top">Top</a>   <script src="https://code.jquery.com/jquery-3.3.1.min.js"></script> <script src="https://cdnjs.cloudflare.com/ajax/libs/popper.js/1.14.7/umd/popper.min.js"></script> <script src="https://stackpath.bootstrapcdn.com/bootstrap/4.3.1/js/bootstrap.min.js"></script>  <script> jQuery(function($) { $(window).scroll(function fix_element() { $('#target').css( $(window).scrollTop() > 100 ? 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