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class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?utm_source=donate&utm_medium=sidebar&utm_campaign=spontaneous&uselang=zh-hans"><span>资助维基百科</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E5%88%9B%E5%BB%BA%E8%B4%A6%E6%88%B7&returnto=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="我们推荐您创建账号并登录，但这不是强制性的"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>创建账号</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=Special:%E7%94%A8%E6%88%B7%E7%99%BB%E5%BD%95&returnto=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="建议你登录，尽管并非必须。[o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>登录</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> 未登录编辑者的页面 <a href="/wiki/Help:%E6%96%B0%E6%89%8B%E5%85%A5%E9%97%A8" aria-label="了解有关编辑的更多信息"><span>了解详情</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%B4%A1%E7%8C%AE" title="来自此IP地址的编辑列表[y]" accesskey="y"><span>贡献</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/Special:%E6%88%91%E7%9A%84%E8%AE%A8%E8%AE%BA%E9%A1%B5" title="对于来自此IP地址编辑的讨论[n]" accesskey="n"><span>讨论</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="站点"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目录" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目录</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">移至侧栏</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">隐藏</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">序言</div> </a> </li> <li id="toc-化學" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#化學"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>化學</span> </div> </a> <ul id="toc-化學-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-體內同半胱胺酸上升" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#體內同半胱胺酸上升"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>體內同半胱胺酸上升</span> </div> </a> <ul id="toc-體內同半胱胺酸上升-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-心血管風險" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#心血管風險"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>心血管風險</span> </div> </a> <ul id="toc-心血管風險-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-骨質脆弱" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#骨質脆弱"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>骨質脆弱</span> </div> </a> <ul id="toc-骨質脆弱-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-參考" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#參考"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>參考</span> </div> </a> <ul id="toc-參考-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-外部連結" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#外部連結"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>外部連結</span> </div> </a> <ul id="toc-外部連結-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目录" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="开关目录" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">开关目录</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">高半胱氨酸</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="前往另一种语言写成的文章。32种语言可用" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-32" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">32种语言</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%87%D9%88%D9%85%D9%88%D8%B3%D9%8A%D8%B3%D8%AA%D9%8A%D9%86" title="هوموسيستين – 阿拉伯语" lang="ar" hreflang="ar" data-title="هوموسيستين" data-language-autonym="العربية" data-language-local-name="阿拉伯语" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%87%D9%88%D9%85%D9%88%D8%B3%DB%8C%D8%B3%D8%AA%D8%A6%DB%8C%D9%86" title="هوموسیستئین – South Azerbaijani" lang="azb" hreflang="azb" data-title="هوموسیستئین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Homociste%C3%AFna" title="Homocisteïna – 加泰罗尼亚语" lang="ca" hreflang="ca" data-title="Homocisteïna" data-language-autonym="Català" data-language-local-name="加泰罗尼亚语" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Homocystein" title="Homocystein – 捷克语" lang="cs" hreflang="cs" data-title="Homocystein" data-language-autonym="Čeština" data-language-local-name="捷克语" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Homocystein" title="Homocystein – 德语" lang="de" hreflang="de" data-title="Homocystein" data-language-autonym="Deutsch" data-language-local-name="德语" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%9F%CE%BC%CE%BF%CE%BA%CF%85%CF%83%CF%84%CE%B5%CE%90%CE%BD%CE%B7" title="Ομοκυστεΐνη – 希腊语" lang="el" hreflang="el" data-title="Ομοκυστεΐνη" data-language-autonym="Ελληνικά" data-language-local-name="希腊语" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Homocysteine" title="Homocysteine – 英语" lang="en" hreflang="en" data-title="Homocysteine" data-language-autonym="English" data-language-local-name="英语" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Homociste%C3%ADna" title="Homocisteína – 西班牙语" lang="es" hreflang="es" data-title="Homocisteína" data-language-autonym="Español" data-language-local-name="西班牙语" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%87%D9%88%D9%85%D9%88%D8%B3%DB%8C%D8%B3%D8%AA%D8%A6%DB%8C%D9%86" title="هوموسیستئین – 波斯语" lang="fa" hreflang="fa" data-title="هوموسیستئین" data-language-autonym="فارسی" data-language-local-name="波斯语" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Homokysteiini" title="Homokysteiini – 芬兰语" lang="fi" hreflang="fi" data-title="Homokysteiini" data-language-autonym="Suomi" data-language-local-name="芬兰语" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Homocyst%C3%A9ine" title="Homocystéine – 法语" lang="fr" hreflang="fr" data-title="Homocystéine" data-language-autonym="Français" data-language-local-name="法语" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Homociste%C3%ADna" title="Homocisteína – 加利西亚语" lang="gl" hreflang="gl" data-title="Homocisteína" data-language-autonym="Galego" data-language-local-name="加利西亚语" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%94%D7%95%D7%9E%D7%95%D7%A6%D7%99%D7%A1%D7%98%D7%90%D7%99%D7%9F" title="הומוציסטאין – 希伯来语" lang="he" hreflang="he" data-title="הומוציסטאין" data-language-autonym="עברית" data-language-local-name="希伯来语" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-hi mw-list-item"><a href="https://hi.wikipedia.org/wiki/%E0%A4%B9%E0%A5%8B%E0%A4%AE%E0%A5%8B%E0%A4%B8%E0%A4%BF%E0%A4%B8%E0%A5%8D%E0%A4%9F%E0%A4%BF%E0%A4%A8" title="होमोसिस्टिन – 印地语" lang="hi" hreflang="hi" data-title="होमोसिस्टिन" data-language-autonym="हिन्दी" data-language-local-name="印地语" class="interlanguage-link-target"><span>हिन्दी</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/Homocisztein" title="Homocisztein – 匈牙利语" lang="hu" hreflang="hu" data-title="Homocisztein" data-language-autonym="Magyar" data-language-local-name="匈牙利语" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D5%80%D5%B8%D5%B4%D5%B8%D6%81%D5%AB%D5%BD%D5%BF%D5%A5%D5%AB%D5%B6" title="Հոմոցիստեին – 亚美尼亚语" lang="hy" hreflang="hy" data-title="Հոմոցիստեին" data-language-autonym="Հայերեն" data-language-local-name="亚美尼亚语" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Omocisteina" title="Omocisteina – 意大利语" lang="it" hreflang="it" data-title="Omocisteina" data-language-autonym="Italiano" data-language-local-name="意大利语" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%9B%E3%83%A2%E3%82%B7%E3%82%B9%E3%83%86%E3%82%A4%E3%83%B3" title="ホモシステイン – 日语" lang="ja" hreflang="ja" data-title="ホモシステイン" data-language-autonym="日本語" data-language-local-name="日语" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%ED%98%B8%EB%AA%A8%EC%8B%9C%EC%8A%A4%ED%85%8C%EC%9D%B8" title="호모시스테인 – 韩语" lang="ko" hreflang="ko" data-title="호모시스테인" data-language-autonym="한국어" data-language-local-name="韩语" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Homocisteinas" title="Homocisteinas – 立陶宛语" lang="lt" hreflang="lt" data-title="Homocisteinas" data-language-autonym="Lietuvių" data-language-local-name="立陶宛语" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-mk mw-list-item"><a href="https://mk.wikipedia.org/wiki/%D0%A5%D0%BE%D0%BC%D0%BE%D1%86%D0%B8%D1%81%D1%82%D0%B5%D0%B8%D0%BD" title="Хомоцистеин – 马其顿语" lang="mk" hreflang="mk" data-title="Хомоцистеин" data-language-autonym="Македонски" data-language-local-name="马其顿语" class="interlanguage-link-target"><span>Македонски</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Homocyste%C3%AFne" title="Homocysteïne – 荷兰语" lang="nl" hreflang="nl" data-title="Homocysteïne" data-language-autonym="Nederlands" data-language-local-name="荷兰语" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Homocysteina" title="Homocysteina – 波兰语" lang="pl" hreflang="pl" data-title="Homocysteina" data-language-autonym="Polski" data-language-local-name="波兰语" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Homociste%C3%ADna" title="Homocisteína – 葡萄牙语" lang="pt" hreflang="pt" data-title="Homocisteína" data-language-autonym="Português" data-language-local-name="葡萄牙语" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Homocistein%C4%83" title="Homocisteină – 罗马尼亚语" lang="ro" hreflang="ro" data-title="Homocisteină" data-language-autonym="Română" data-language-local-name="罗马尼亚语" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%93%D0%BE%D0%BC%D0%BE%D1%86%D0%B8%D1%81%D1%82%D0%B5%D0%B8%D0%BD" title="Гомоцистеин – 俄语" lang="ru" hreflang="ru" data-title="Гомоцистеин" data-language-autonym="Русский" data-language-local-name="俄语" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Homocistein" title="Homocistein – 塞尔维亚-克罗地亚语" lang="sh" hreflang="sh" data-title="Homocistein" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="塞尔维亚-克罗地亚语" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Homocistein" title="Homocistein – 塞尔维亚语" lang="sr" hreflang="sr" data-title="Homocistein" data-language-autonym="Српски / srpski" data-language-local-name="塞尔维亚语" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Homocystein" title="Homocystein – 瑞典语" lang="sv" hreflang="sv" data-title="Homocystein" data-language-autonym="Svenska" data-language-local-name="瑞典语" class="interlanguage-link-target"><span>Svenska</span></a></li><li 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<table class="infobox ib-chembox nounderlines" cellspacing="0" cellpadding="3" rules="all" style="background-color:#f0f0f0; float:right; margin: 0 0 1em 1em; border-color: #aaaaaa; border-style:solid; border:1px; border-collapse:collapse; empty-cells:show; width:305px; font-size:90%;"> <tbody><tr> <th colspan="2" style="font-size:120%; text-align:center; background:#d6e0dc;">高半胱氨酸 </th></tr> <tr> <td colspan="2" style="background:#ffffff; text-align:center;"><span typeof="mw:File"><a href="/wiki/File:Homocysteine_racemic.png" class="mw-file-description" title="Skeletal formula"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/80/Homocysteine_racemic.png/180px-Homocysteine_racemic.png" decoding="async" width="180" height="99" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/80/Homocysteine_racemic.png/270px-Homocysteine_racemic.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/80/Homocysteine_racemic.png/360px-Homocysteine_racemic.png 2x" data-file-width="831" data-file-height="457" /></a></span> </td></tr> <tr> <td colspan="2" style="background:#ffffff; text-align:center;"><span typeof="mw:File"><a href="/wiki/File:L-Homocysteine-3D-balls.png" class="mw-file-description" title="Ball-and-stick model"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8e/L-Homocysteine-3D-balls.png/120px-L-Homocysteine-3D-balls.png" decoding="async" width="120" height="175" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8e/L-Homocysteine-3D-balls.png/180px-L-Homocysteine-3D-balls.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8e/L-Homocysteine-3D-balls.png/240px-L-Homocysteine-3D-balls.png 2x" data-file-width="657" data-file-height="956" /></a></span> </td></tr> <tr> <td colspan="2" style="max-width:305px; word-wrap: break-word; text-align: center;"><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC名</a><br />2-氨基-4-硫基丁酸 </td></tr> <tr> <th style="background:#D6E0DC; text-align:center;" colspan="2">识别 </th></tr> <tr> <td><a href="/wiki/CAS%E5%8F%B7" title="CAS号">CAS号</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=454-29-5">454-29-5</a></span> <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup><br /><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=6027-13-0">6027-13-0</a></span>（<small>L</small>型） <sup> <span typeof="mw:File"><span><img alt="check" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/7px-Yes_check.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/11px-Yes_check.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Yes_check.svg/14px-Yes_check.svg.png 2x" data-file-width="600" data-file-height="600" /></span></span><span style="display:none">Y</span></sup> </td></tr> <tr> <td><a href="/wiki/PubChem" title="PubChem">PubChem</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/778">778</a></span> </td></tr> <tr> <td><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.chemspider.com/757">757</a></span> </td></tr> <tr> <td><a href="/wiki/SMILES" class="mw-redirect" title="SMILES">SMILES</a> </td> <td><div style="word-break:break-all;"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div> </div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0;"><li style="line-height: inherit; margin: 0"><span lang="en">C(CS)C(C(=O)O)N</span></li></ul> </div></div> </td></tr> <tr> <td><a href="/wiki/%E5%9B%BD%E9%99%85%E5%8C%96%E5%90%88%E7%89%A9%E6%A0%87%E8%AF%86" title="国际化合物标识">InChI</a> </td> <td><div style="word-break:break-all;"><div class="collapsible-list mw-collapsible mw-collapsed" style="text-align: left;"> <div style="line-height: 1.6em; font-weight: bold;"><div> </div></div> <ul class="mw-collapsible-content" style="margin-top: 0; margin-bottom: 0; line-height: inherit; list-style: none; margin-left: 0;"><li style="line-height: inherit; margin: 0">1/C4H9NO2S/c5-3(1-2-8)4(6)7/h3,8H,1-2,5H2,(H,6,7)</li></ul> </div></div> </td></tr> <tr> <td><a href="/wiki/%E5%9B%BD%E9%99%85%E5%8C%96%E5%90%88%E7%89%A9%E6%A0%87%E8%AF%86" title="国际化合物标识">InChIKey</a> </td> <td><small>FFFHZYDWPBMWHY-UHFFFAOYAS</small> </td></tr> <tr> <td><a href="/wiki/%E6%AC%A7%E7%9B%9F%E7%BC%96%E5%8F%B7" class="mw-redirect" title="欧盟编号">EC编号</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://ecb.jrc.ec.europa.eu/esis/index.php?GENRE=ECNO&ENTREE=207-222-9">207-222-9</a></span> </td></tr> <tr> <td><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17230">17230</a></span> </td></tr> <tr> <td><a href="/wiki/KEGG" title="KEGG">KEGG</a> </td> <td><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.genome.ad.jp/dbget-bin/www_bget?cpd:C05330">C05330</a></span> </td></tr> <tr> <th style="background:#D6E0DC; text-align:center;" colspan="2">性质 </th></tr> <tr> <td><a href="/wiki/%E5%8C%96%E5%AD%A6%E5%BC%8F" title="化学式">化学式</a> </td> <td><span lang="en">C<sub>4</sub>H<sub>9</sub>NO<sub>2</sub>S</span> </td></tr> <tr> <td><a href="/wiki/%E6%91%A9%E5%B0%94%E8%B4%A8%E9%87%8F" title="摩尔质量">摩尔质量</a> </td> <td>135.18 g/mol g·mol⁻¹ </td></tr> <tr> <td style="background:#D6E0DC; text-align:center;" colspan="2">若非注明，所有数据均出自<a href="/wiki/%E6%A0%87%E5%87%86%E7%8A%B6%E6%80%81" title="标准状态">标准状态（25 ℃，100 kPa）</a>下。 </td></tr></tbody></table> <p><b>同半胱胺酸</b>（英語：<span lang="en">Homocysteine</span>）又稱<b>同型半胱氨酸</b>、<b>同半胱氨酸</b>、<b>類半胱胺酸</b><sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>，是<a href="/wiki/%E8%83%BA%E5%9F%BA%E9%85%B8" class="mw-redirect" title="胺基酸">胺基酸</a><a href="/wiki/%E5%8D%8A%E8%83%B1%E8%83%BA%E9%85%B8" class="mw-redirect" title="半胱胺酸">半胱胺酸</a>的<a href="/wiki/%E5%90%8C%E7%B3%BB%E7%89%A9" title="同系物">同系物</a>，在<a href="/w/index.php?title=%E6%94%AF%E9%8F%88&action=edit&redlink=1" class="new" title="支鏈（页面不存在）">支鏈</a>部份<a href="/wiki/%E7%A1%AB%E9%86%87%E5%9F%BA" class="mw-redirect" title="硫醇基">硫醇基</a>（-SH）前包含一個額外的<a href="/wiki/%E4%BA%9E%E7%94%B2%E5%9F%BA" class="mw-redirect" title="亞甲基">亞甲基</a>（-CH<sub>2</sub>-）。 </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="化學"><span id=".E5.8C.96.E5.AD.B8"></span>化學</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&section=1" title="编辑章节：化學"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure typeof="mw:File/Thumb"><a href="/wiki/File:Methionine_pathway_(zh-cn).svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/Methionine_pathway_%28zh-cn%29.svg/500px-Methionine_pathway_%28zh-cn%29.svg.png" decoding="async" width="500" height="500" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/Methionine_pathway_%28zh-cn%29.svg/750px-Methionine_pathway_%28zh-cn%29.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/da/Methionine_pathway_%28zh-cn%29.svg/1000px-Methionine_pathway_%28zh-cn%29.svg.png 2x" data-file-width="500" data-file-height="500" /></a><figcaption>同半胱胺酸可以轉化形成甲硫胺酸或胱硫醚</figcaption></figure> <p>高半胱氨酸的額外<a href="/wiki/%E4%BA%9E%E7%94%B2%E5%9F%BA" class="mw-redirect" title="亞甲基">亞甲基</a>使<a href="/wiki/%E7%A1%AB%E9%86%87%E5%9F%BA" class="mw-redirect" title="硫醇基">硫醇基</a>更接近<a href="/wiki/%E7%BE%A7%E5%9F%BA" title="羧基">羧基</a>，令它能起動<a href="/wiki/%E5%8C%96%E5%AD%B8%E5%8F%8D%E6%87%89" class="mw-redirect" title="化學反應">化學反應</a>形成一個五元環，稱為<a href="/w/index.php?title=%E5%90%8C%E5%8D%8A%E8%83%B1%E8%83%BA%E9%85%B8%E7%A1%AB%E5%85%A7%E9%85%AF&action=edit&redlink=1" class="new" title="同半胱胺酸硫內酯（页面不存在）">同半胱胺酸硫內酯</a>。當<a href="/wiki/%E8%83%BA%E5%9F%BA%E9%85%B8" class="mw-redirect" title="胺基酸">胺基酸</a>正常與它的毗鄰形成一個<a href="/wiki/%E8%82%BD%E9%8D%B5" class="mw-redirect" title="肽鍵">肽鍵</a>就會產生這種反應。同半胱胺酸不適合與<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B3%AA" class="mw-redirect" title="蛋白質">蛋白質</a>混合，這是因含有同半胱胺酸的蛋白質會自行分解。 </p><p>高半胱氨酸是從<a href="/wiki/S-%E8%85%BA%E8%8B%B7%E5%9F%BA%E8%9B%8B%E6%B0%A8%E9%85%B8" class="mw-redirect" title="S-腺苷基蛋氨酸">S-腺苷基蛋氨酸</a>透過兩個反應步驟形成。並可逆形成<a href="/wiki/%E8%9B%8B%E6%B0%A8%E9%85%B8" class="mw-redirect" title="蛋氨酸">蛋氨酸</a>，或經過<a href="/w/index.php?title=%E8%BD%89%E7%A1%AB%E9%80%94%E5%BE%91&action=edit&redlink=1" class="new" title="轉硫途徑（页面不存在）">轉硫途徑</a>而可逆為<a href="/wiki/%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="半胱氨酸">半胱氨酸</a>或<a href="/wiki/%E7%89%9B%E7%A3%BA%E9%85%B8" title="牛磺酸">牛磺酸</a>。雖然高半胱氨酸可逆回為半胱氨酸，但沒有證據顯示人類食用同半胱胺酸可取代半胱胺酸的攝取。<sup id="cite_ref-AnRvNutrition1999-Selhub_2-0" class="reference"><a href="#cite_note-AnRvNutrition1999-Selhub-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="體內同半胱胺酸上升"><span id=".E9.AB.94.E5.85.A7.E5.90.8C.E5.8D.8A.E8.83.B1.E8.83.BA.E9.85.B8.E4.B8.8A.E5.8D.87"></span>體內同半胱胺酸上升</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&section=2" title="编辑章节：體內同半胱胺酸上升"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r85100532"><div role="note" class="hatnote navigation-not-searchable">主条目：<a href="/wiki/%E9%AB%98%E5%90%8C%E5%9E%8B%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8%E8%A1%80%E7%97%87" title="高同型半胱氨酸血症">高同型半胱氨酸血症</a></div> <p>缺乏<a href="/wiki/%E7%B6%AD%E4%BB%96%E5%91%BD" class="mw-redirect" title="維他命">維他命</a>如<a href="/wiki/%E5%8F%B6%E9%85%B8" title="叶酸">葉酸</a>（B<sub>9</sub>）、<a href="/wiki/%E5%90%A1%E5%93%86%E9%86%87" title="吡哆醇">吡哆醇</a>（B<sub>6</sub>）或<a href="/wiki/%E9%88%B7%E8%83%BA%E7%B4%A0" class="mw-redirect" title="鈷胺素">鈷胺素</a>（B<sub>12</sub>），作為<a href="/wiki/%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%B8" class="mw-redirect" title="生物化學">生物化學</a>反應的結果，都會造成體內同半胱胺酸囤積。<sup id="cite_ref-AmJClinNutrition1994-Miller_3-0" class="reference"><a href="#cite_note-AmJClinNutrition1994-Miller-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> 補充吡哆醇、葉酸、鈷胺素或<a href="/w/index.php?title=%E4%B8%89%E7%94%B2%E5%9F%BA%E7%94%98%E6%B0%A8%E9%85%B8&action=edit&redlink=1" class="new" title="三甲基甘氨酸（页面不存在）">三甲基甘氨酸</a>會減少<a href="/wiki/%E8%A1%80%E6%B6%B2" title="血液">血液</a>內的高半胱氨酸的濃度。<sup id="cite_ref-ExpertOpPharm2001-Coen_4-0" class="reference"><a href="#cite_note-ExpertOpPharm2001-Coen-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-NYT2006-Chrichton_5-0" class="reference"><a href="#cite_note-NYT2006-Chrichton-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup>體內高濃度的同半胱胺酸與<a href="/wiki/%E5%85%A7%E7%9A%AE%E7%B4%B0%E8%83%9E" class="mw-redirect" title="內皮細胞">內皮細胞</a>的<a href="/wiki/%E9%9D%9E%E5%B0%8D%E7%A8%B1%E6%80%A7%E4%BA%8C%E7%94%B2%E5%9F%BA%E7%B2%BE%E6%B0%A8%E9%85%B8" title="非對稱性二甲基精氨酸">非對稱性二甲基精氨酸</a>的高濃度有關。 </p><p>高半胱氨酸的攀升在罕見的遺傳性疾病<a href="/wiki/%E9%AB%98%E8%83%B1%E8%83%BA%E9%85%B8%E5%B0%BF%E7%97%87" title="高胱胺酸尿症">高胱胺酸尿症</a>及缺乏<a href="/w/index.php?title=%E4%BA%9E%E7%94%B2%E5%9F%BA%E5%9B%9B%E6%B0%AB%E8%91%89%E9%85%B8%E9%82%84%E5%8E%9F%E9%85%B6&action=edit&redlink=1" class="new" title="亞甲基四氫葉酸還原酶（页面不存在）">亞甲基四氫葉酸還原酶</a>。後者是較普遍而不常發現，而同半胱胺酸較高的人會容易患上<a href="/w/index.php?title=%E8%A1%80%E6%A0%93%E7%97%87&action=edit&redlink=1" class="new" title="血栓症（页面不存在）">血栓症</a>及<a href="/wiki/%E5%BF%83%E8%A1%80%E7%AE%A1%E7%96%BE%E7%97%85" title="心血管疾病">心血管疾病</a>。 </p><p>同半胱胺酸在高濃度的<a href="/wiki/%E5%A4%9A%E9%85%9A%E6%8A%97%E6%B0%A7%E5%8C%96%E5%8A%91" title="多酚抗氧化劑">多酚抗氧化劑</a>下會調降，而多酚抗氧化劑被認為是對<a href="/wiki/%E5%BF%83%E8%A1%80%E7%AE%A1%E7%B3%BB%E7%BB%9F" class="mw-redirect" title="心血管系统">心血管系統</a>及<a href="/wiki/%E5%85%8D%E7%96%AB%E7%B3%BB%E7%B5%B1" class="mw-redirect" title="免疫系統">免疫系統</a>有某些健康益處。多酚抗氧化劑可以調降心血管疾病的重要化合物<a href="/wiki/%E6%B4%BB%E6%80%A7%E6%B0%A7" class="mw-redirect" title="活性氧">活性氧</a>的形成。透過同半胱胺酸的自動氧化成活性氧會導致生物損害。 </p> <div class="mw-heading mw-heading2"><h2 id="心血管風險"><span id=".E5.BF.83.E8.A1.80.E7.AE.A1.E9.A2.A8.E9.9A.AA"></span>心血管風險</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&section=3" title="编辑章节：心血管風險"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/%E8%A1%80%E6%B8%85" title="血清">血清</a>內高半胱氨酸的高水平是潛在<a href="/wiki/%E5%BF%83%E8%A1%80%E7%AE%A1%E7%96%BE%E7%97%85" title="心血管疾病">心血管疾病</a>的標記，也是造成<a href="/wiki/%E4%B8%AD%E9%A2%A8" title="中風">中風</a>的危險因子之一。目前研究的主題方向便是，同半胱胺酸本身是否存在問題，亦或現代問題的指標。<sup id="cite_ref-BBC2005-NewsBvit_6-0" class="reference"><a href="#cite_note-BBC2005-NewsBvit-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>2006年有一項研究指出，雖然以攝取<a href="/wiki/%E7%B6%AD%E4%BB%96%E5%91%BD" class="mw-redirect" title="維他命">維他命</a>降低體內的同半胱胺酸並不能於短時間內見效，但是在中風個案中卻顯著地降低了25%。<sup id="cite_ref-NEJM2006a_7-0" class="reference"><a href="#cite_note-NEJM2006a-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup>縱然整體死亡率並沒有明顯改變，但亦會為患有嚴重<a href="/wiki/%E5%8B%95%E8%84%88" class="mw-redirect" title="動脈">動脈</a>衰竭的病患帶來幫助。降低同半胱胺酸並非快速回復動脈結構破壞的方法。但是，<a href="/wiki/%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%B8" class="mw-redirect" title="生物化學">生物化學</a>強烈支持同半胱胺酸會促進動脈的三個主要結構（<a href="/wiki/%E8%86%A0%E5%8E%9F%E8%9B%8B%E7%99%BD" title="膠原蛋白">膠原蛋白</a>、<a href="/wiki/%E5%BC%B9%E6%80%A7%E8%9B%8B%E7%99%BD" title="弹性蛋白">彈性蛋白</a>及<a href="/w/index.php?title=%E5%A4%9A%E9%86%A3%E8%9B%8B%E7%99%BD&action=edit&redlink=1" class="new" title="多醣蛋白（页面不存在）">多醣蛋白</a>）的衰退及阻止增生。高半胱氨酸將會永久性地造成<a href="/wiki/%E5%8D%8A%E8%83%B1%E8%83%BA%E9%85%B8" class="mw-redirect" title="半胱胺酸">半胱胺酸</a>（其雙硫鍵架橋）及<a href="/wiki/%E8%9B%8B%E7%99%BD%E8%B3%AA" class="mw-redirect" title="蛋白質">蛋白質</a>內<a href="/wiki/%E9%9B%A2%E6%B0%A8%E9%85%B8" class="mw-redirect" title="離氨酸">離氨酸</a>的殘基降解，逐漸影響其功能及結構。簡單來說，高半胱氨酸是一種具腐蝕性，又能長時間存在的膠原蛋白及彈性蛋白，或達一生之久的<a href="/w/index.php?title=%E7%B5%90%E7%B7%A0%E7%B5%84%E7%B9%94%E8%9B%8B%E7%99%BD%E8%B3%AA&action=edit&redlink=1" class="new" title="結締組織蛋白質（页面不存在）">結締組織蛋白質</a>的物質。這種長遠的影響在臨床研究上是很難發現的。降低體內高半胱氨酸過高，其目的在於預防，雖然在治療上無法立即見效但為可行的方法。<sup id="cite_ref-JAmCollCardiol2006-Zoungas_8-0" class="reference"><a href="#cite_note-JAmCollCardiol2006-Zoungas-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-NEJM2006a_7-1" class="reference"><a href="#cite_note-NEJM2006a-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-NEJM2006-Bonna_9-0" class="reference"><a href="#cite_note-NEJM2006-Bonna-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="骨質脆弱"><span id=".E9.AA.A8.E8.B3.AA.E8.84.86.E5.BC.B1"></span>骨質脆弱</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&section=4" title="编辑章节：骨質脆弱"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>體內同半胱胺酸偏高會增加老年人<a href="/wiki/%E9%AA%A8%E6%8A%98" title="骨折">骨折</a>的風險。<sup id="cite_ref-NEJM2004-McLean_10-0" class="reference"><a href="#cite_note-NEJM2004-McLean-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-NEJM2004-vanMeurs_11-0" class="reference"><a href="#cite_note-NEJM2004-vanMeurs-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup>同半胱胺酸雖然不會影響骨質密度。但會妨礙<a href="/wiki/%E8%86%A0%E5%8E%9F%E8%9B%8B%E7%99%BD" title="膠原蛋白">膠原蛋白</a>纖維與組織的連接，進而影響體內的膠原蛋白。 </p><p><a href="/wiki/%E7%B6%AD%E4%BB%96%E5%91%BD" class="mw-redirect" title="維他命">維他命</a>補充劑能減少同半胱胺酸對膠原蛋白的作用。由於老人因胃酸分泌減少，而不能有效地從食物中吸收<a href="/wiki/%E9%88%B7%E8%83%BA%E7%B4%A0" class="mw-redirect" title="鈷胺素">鈷胺素</a>（B<sub>12</sub>），便能以補充劑的方式改善。 </p> <div class="mw-heading mw-heading2"><h2 id="參考"><span id=".E5.8F.83.E8.80.83"></span>參考</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&section=5" title="编辑章节：參考"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ol 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N Engl J Med. 2006. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/16531613?dopt=Abstract">PMID 16531613</a> <a rel="nofollow" class="external text" href="http://content.nejm.org/cgi/reprint/NEJMoa060900v1.pdf">原整文章</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&rft.atitle=Homocysteine+Lowering+with+Folic+Acid+and+B+Vitamins+in+Vascular+Disease&rft.date=2006&rft.genre=article&rft.jtitle=N+Engl+J+Med&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-JAmCollCardiol2006-Zoungas-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-JAmCollCardiol2006-Zoungas_8-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Zoungas S, McGrath BP, Branley P, Kerr PG, Muske C, Wolfe R, Atkins RC, Nicholls K, Fraenkel M, Hutchison BG, Walker R, McNeil JJ. Cardiovascular morbidity and mortality in the Atherosclerosis and Folic Acid Supplementation Trial (ASFAST) in chronic renal failure: a multicenter, randomized, controlled trial. J Am Coll Cardiol. 2006, <b>47</b> (6): 1108–16. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/16545638?dopt=Abstract">PMID 16545638</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&rft.atitle=Cardiovascular+morbidity+and+mortality+in+the+Atherosclerosis+and+Folic+Acid+Supplementation+Trial+%28ASFAST%29+in+chronic+renal+failure%3A+a+multicenter%2C+randomized%2C+controlled+trial&rft.au=Zoungas+S%2C+McGrath+BP%2C+Branley+P%2C+Kerr+PG%2C+Muske+C%2C+Wolfe+R%2C+Atkins+RC%2C+Nicholls+K%2C+Fraenkel+M%2C+Hutchison+BG%2C+Walker+R%2C+McNeil+JJ&rft.date=2006&rft.genre=article&rft.issue=6&rft.jtitle=J+Am+Coll+Cardiol&rft.pages=1108-16&rft.volume=47&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-NEJM2006-Bonna-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-NEJM2006-Bonna_9-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">Bonaa KH, Njolstad I, Ueland PM, Schirmer H, Tverdal A, Steigen T, Wang H, Nordrehaug JE, Arnesen E, Rasmussen K. Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction. N Engl J Med. 2006. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/16531614?dopt=Abstract">PMID 16531614</a> <a rel="nofollow" class="external text" href="http://content.nejm.org/cgi/reprint/NEJMoa055227v1.pdf">原整文章</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&rft.atitle=Homocysteine+Lowering+and+Cardiovascular+Events+after+Acute+Myocardial+Infarction&rft.au=Bonaa+KH%2C+Njolstad+I%2C+Ueland+PM%2C+Schirmer+H%2C+Tverdal+A%2C+Steigen+T%2C+Wang+H%2C+Nordrehaug+JE%2C+Arnesen+E%2C+Rasmussen+K&rft.date=2006&rft.genre=article&rft.jtitle=N+Engl+J+Med&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-NEJM2004-McLean-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-NEJM2004-McLean_10-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">McLean RR; et al. Homocysteine as a predictive factor for hip fracture in older persons.. New England Journal of Medicine. 2004, <b>350</b>: 2042–2049. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/15141042?dopt=Abstract">PMID 15141042</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&rft.atitle=Homocysteine+as+a+predictive+factor+for+hip+fracture+in+older+persons.&rft.au=McLean+RR&rft.date=2004&rft.genre=article&rft.jtitle=New+England+Journal+of+Medicine&rft.pages=2042-2049&rft.volume=350&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33"> 引文格式1维护：显式使用等标签 (<a href="/wiki/Category:%E5%BC%95%E6%96%87%E6%A0%BC%E5%BC%8F1%E7%BB%B4%E6%8A%A4%EF%BC%9A%E6%98%BE%E5%BC%8F%E4%BD%BF%E7%94%A8%E7%AD%89%E6%A0%87%E7%AD%BE" title="Category:引文格式1维护：显式使用等标签">link</a>)</span> <a rel="nofollow" class="external text" href="http://content.nejm.org/cgi/content/full/350/20/2042">原整文章</a> （<a rel="nofollow" class="external text" href="//web.archive.org/web/20090309124012/http://content.nejm.org/cgi/content/full/350/20/2042">页面存档备份</a>，存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>）</span> </li> <li id="cite_note-NEJM2004-vanMeurs-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-NEJM2004-vanMeurs_11-0">^</a></b></span> <span class="reference-text"><cite class="citation journal">van Meurs JB; et al. Homocysteine levels and the risk of osteoporotic fracture.. New England Journal of Medicine. 2004, <b>350</b>: 2033–2041. <a class="external mw-magiclink-pmid" rel="nofollow" href="//www.ncbi.nlm.nih.gov/pubmed/15141041?dopt=Abstract">PMID 15141041</a>.</cite><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&rft.atitle=Homocysteine+levels+and+the+risk+of+osteoporotic+fracture.&rft.au=van+Meurs+JB&rft.date=2004&rft.genre=article&rft.jtitle=New+England+Journal+of+Medicine&rft.pages=2033-2041&rft.volume=350&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span><span class="citation-comment" style="display:none; color:#33aa33"> 引文格式1维护：显式使用等标签 (<a href="/wiki/Category:%E5%BC%95%E6%96%87%E6%A0%BC%E5%BC%8F1%E7%BB%B4%E6%8A%A4%EF%BC%9A%E6%98%BE%E5%BC%8F%E4%BD%BF%E7%94%A8%E7%AD%89%E6%A0%87%E7%AD%BE" title="Category:引文格式1维护：显式使用等标签">link</a>)</span> <a rel="nofollow" class="external text" href="http://content.nejm.org/cgi/content/full/350/20/2033">原整文章</a> （<a rel="nofollow" class="external text" href="//web.archive.org/web/20100117061213/http://content.nejm.org/cgi/content/full/350/20/2033">页面存档备份</a>，存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>）</span> </li> </ol> <div class="mw-heading mw-heading2"><h2 id="外部連結"><span id=".E5.A4.96.E9.83.A8.E9.80.A3.E7.B5.90"></span>外部連結</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&section=6" title="编辑章节：外部連結"><span>编辑</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20071008054923/http://www.muscle-nerve.com/ReadNews.asp?NewsID=313">高同型半胱氨酸血症</a></li> <li><a rel="nofollow" class="external text" href="http://www.sdccl.com.cn/ltxxlr.asp?id=1253">同型半胱氨酸---心脑血管疾病的独立危险因子</a> （<a rel="nofollow" class="external text" href="//web.archive.org/web/20070928225520/http://www.sdccl.com.cn/ltxxlr.asp?id=1253">页面存档备份</a>，存于<a href="/wiki/%E4%BA%92%E8%81%94%E7%BD%91%E6%A1%A3%E6%A1%88%E9%A6%86" title="互联网档案馆">互联网档案馆</a>）</li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20061111044539/http://www.thorne.com/altmedrev/fulltext/meth1-4.html">Methionine and Homocysteine</a></li> <li><a rel="nofollow" class="external text" href="https://web.archive.org/web/20060822023746/http://www.diabetesforum.net/cgi-bin/display_engine.pl?category_id=8&content_id=232">Structure, Properties, and metabolism of Homocysteine</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r84265675">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist 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href="/wiki/%E4%BB%A3%E8%AC%9D%E4%B8%AD%E9%96%93%E7%94%A2%E7%89%A9" title="代謝中間產物">代謝中間產物</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%9F%E9%85%AE%E6%B0%A8%E5%9F%BA%E9%85%B8" title="生酮氨基酸">生酮氨基酸</a>→<a href="/wiki/%E4%B9%99%E9%85%B0%E8%BE%85%E9%85%B6A" title="乙酰辅酶A">乙酰辅酶A</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E9%9B%A2%E8%83%BA%E9%85%B8" title="離胺酸">赖氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E9%85%B5%E6%AF%8D%E6%B0%A8%E9%85%B8" title="酵母氨酸">酵母氨酸</a></li> <li><a href="/wiki/%E9%98%BF%E9%9B%A2%E8%83%BA%E9%85%B8" title="阿離胺酸">ε-醛赖氨酸</a></li> <li><a href="/wiki/%CE%91-%E6%B0%A8%E5%9F%BA%E5%B7%B1%E4%BA%8C%E9%85%B8" title="Α-氨基己二酸">α-氨基己二酸</a></li> <li><a href="/wiki/%CE%91-%E9%85%AE%E5%B7%B1%E4%BA%8C%E9%85%B8" title="Α-酮己二酸">α-酮己二酸</a></li> <li><a href="/w/index.php?title=%E6%88%8A%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="戊二酰辅酶A（页面不存在）">戊二酰辅酶A</a></li> <li><a href="/w/index.php?title=%E6%88%8A%E7%83%AF%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="戊烯二酰辅酶A（页面不存在）">戊烯二酰辅酶A</a></li> <li><a href="/w/index.php?title=%E5%B7%B4%E8%B1%86%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="巴豆酰辅酶A（页面不存在）">巴豆酰辅酶A</a></li> <li><a href="/w/index.php?title=%CE%92-%E7%BE%9F%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="Β-羟丁酰辅酶A（页面不存在）">β-羟丁酰辅酶A</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E4%BA%AE%E6%B0%A8%E9%85%B8" title="亮氨酸">亮氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%CE%91-%E9%85%AE%E5%BC%82%E5%B7%B1%E9%85%B8" title="Α-酮异己酸">α-酮异己酸</a></li> <li><a href="/w/index.php?title=%E5%BC%82%E6%88%8A%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="异戊酰辅酶A（页面不存在）">异戊酰辅酶A</a></li> <li><a href="/w/index.php?title=%E7%94%B2%E5%9F%BA%E5%B7%B4%E8%B1%86%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="甲基巴豆酰辅酶A（页面不存在）">3-甲基巴豆酰辅酶A</a></li> <li><a href="/w/index.php?title=3-%E7%94%B2%E5%9F%BA%E6%88%8A%E7%83%AF%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="3-甲基戊烯二酰辅酶A（页面不存在）">3-甲基戊烯二酰辅酶A</a></li> <li><a href="/wiki/%E7%BE%9F%E7%94%B2%E5%9F%BA%E6%88%8A%E4%BA%8C%E9%85%B8%E5%8D%95%E9%85%B0%E8%BE%85%E9%85%B6A" title="羟甲基戊二酸单酰辅酶A">β-羟-β-甲戊二酸单酰辅酶A</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%89%B2%E6%B0%A8%E9%85%B8" title="色氨酸">色氨酸</a>→<a href="/wiki/%E4%B8%99%E6%B0%A8%E9%85%B8" title="丙氨酸">丙氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=N%27-%E7%94%B2%E9%85%B0%E7%8A%AC%E5%B0%BF%E6%B0%A8%E9%85%B8&action=edit&redlink=1" class="new" title="N'-甲酰犬尿氨酸（页面不存在）"><i>N'</i>-甲酰犬尿氨酸</a> <ul><li><a href="/wiki/%E7%8A%AC%E5%B0%BF%E6%B0%A8%E9%85%B8" title="犬尿氨酸">犬尿氨酸</a></li> <li><a href="/wiki/%E9%82%BB%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8" title="邻氨基苯甲酸">邻氨基苯甲酸</a></li> <li><a href="/wiki/3-%E7%BE%9F%E5%9F%BA%E7%8A%AC%E5%B0%BF%E6%B0%A8%E9%85%B8" title="3-羟基犬尿氨酸">3-羟基犬尿氨酸</a></li> <li><a href="/w/index.php?title=3-%E7%BE%9F%E5%9F%BA-2-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E7%94%B2%E9%85%B8&action=edit&redlink=1" class="new" title="3-羟基-2-氨基苯甲酸（页面不存在）">3-羟基-2-氨基苯甲酸</a></li> <li><a href="/wiki/2-%E6%B0%A8%E5%9F%BA-3-%E7%BE%A7%E5%9F%BA%E7%B2%98%E5%BA%B7%E9%85%B8%E5%8D%8A%E9%86%9B" title="2-氨基-3-羧基粘康酸半醛">2-氨基-3-羧基粘康酸半醛</a></li> <li><a href="/wiki/2-%E6%B0%A8%E5%9F%BA%E7%B2%98%E5%BA%B7%E9%85%B8%E5%8D%8A%E9%86%9B" title="2-氨基粘康酸半醛">2-氨基粘康酸半醛</a></li> <li><a href="/wiki/2-%E6%B0%A8%E5%9F%BA%E7%B2%98%E5%BA%B7%E9%85%B8" title="2-氨基粘康酸">2-氨基粘康酸</a></li> <li><a href="/w/index.php?title=%E6%88%8A%E4%BA%8C%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="戊二酰辅酶A（页面不存在）">戊二酰辅酶A</a></li></ul></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%9F%E7%B3%96%E6%B0%A8%E5%9F%BA%E9%85%B8" title="生糖氨基酸">生糖氨基酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E4%B8%99%E9%85%AE%E9%85%B8" title="丙酮酸">丙酮酸</a>→<a href="/wiki/%E6%9F%A0%E6%AA%AC%E9%85%B8" class="mw-redirect" title="柠檬酸">柠檬酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="甘氨酸→絲氨酸→" scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%98%E6%B0%A8%E9%85%B8" title="甘氨酸">甘氨酸</a>→<a href="/wiki/%E7%B5%B2%E6%B0%A8%E9%85%B8" title="絲氨酸">絲氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/3-%E7%A3%B7%E9%85%B8%E7%94%98%E6%B2%B9%E9%85%B8" title="3-磷酸甘油酸">3-磷酸甘油酸</a><br /> <p><a href="/wiki/%E7%94%98%E6%B0%A8%E9%85%B8" title="甘氨酸">甘氨酸</a>→<a href="/wiki/%E8%82%8C%E9%85%B8" title="肌酸">肌酸</a>：<a href="/wiki/%E8%83%8D%E5%9F%BA%E4%B9%99%E9%85%B8" title="胍基乙酸">胍基乙酸</a> </p> <ul><li><a href="/w/index.php?title=%E7%A3%B7%E9%85%B8%E8%82%8C%E9%85%B8&action=edit&redlink=1" class="new" title="磷酸肌酸（页面不存在）">磷酸肌酸</a></li> <li><a href="/wiki/%E8%82%8C%E9%85%B8%E9%85%90" title="肌酸酐">肌酸酐</a></li></ul></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8" title="谷氨酸">谷氨酸</a>→<br /><a href="/wiki/%CE%91-%E9%85%AE%E6%88%8A%E4%BA%8C%E9%85%B8" title="Α-酮戊二酸">α-酮戊二酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%BB%84%E6%B0%A8%E9%85%B8" class="mw-redirect" title="组氨酸">组氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <li><a href="/wiki/%E5%B0%BF%E5%88%8A%E9%85%B8" title="尿刊酸">尿刊酸</a></li> <li><a href="/wiki/%E5%92%AA%E5%94%91-4-%E9%85%AE-5-%E4%B8%99%E9%85%B8" title="咪唑-4-酮-5-丙酸">咪唑-4-酮-5-丙酸</a></li> <li><a href="/wiki/%E8%83%BA%E4%BA%9A%E7%94%B2%E5%9F%BA%E8%B0%B7%E6%B0%A8%E9%85%B8" title="胺亚甲基谷氨酸">胺亚甲基谷氨酸</a></li> <li><a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8-1-%E5%8D%8A%E9%86%9B" title="谷氨酸-1-半醛">谷氨酸-1-半醛</a></li> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%84%AF%E6%B0%A8%E9%85%B8" title="脯氨酸">脯氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/w/index.php?title=1-%E5%90%A1%E5%92%AF%E5%95%89-5-%E7%BE%A7%E9%85%B8&action=edit&redlink=1" class="new" title="1-吡咯啉-5-羧酸（页面不存在）">1-吡咯啉-5-羧酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%B2%BE%E6%B0%A8%E9%85%B8" title="精氨酸">精氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%E9%B3%A5%E8%83%BA%E9%85%B8" title="鳥胺酸">鸟氨酸</a></li> <li><a href="/wiki/%E8%85%90%E8%83%BA" title="腐胺">腐胺</a></li> <li><a href="/w/index.php?title=%E8%83%8D%E5%9F%BA%E4%B8%81%E8%83%BA&action=edit&redlink=1" class="new" title="胍基丁胺（页面不存在）">胍基丁胺</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="半胱氨酸">半胱氨酸</a>+<a href="/wiki/%E8%B0%B7%E6%B0%A8%E9%85%B8" title="谷氨酸">谷氨酸</a>→<a href="/wiki/%E8%B0%B7%E8%83%B1%E7%94%98%E8%82%BD" title="谷胱甘肽">谷胱甘肽</a>：<a href="/w/index.php?title=%CE%93-%E8%B0%B7%E6%B0%A8%E9%85%B0%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8&action=edit&redlink=1" class="new" title="Γ-谷氨酰半胱氨酸（页面不存在）">γ-谷氨酰半胱氨酸</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E4%B8%99%E9%85%B0%E8%BE%85%E9%85%B6A" title="丙酰辅酶A">丙酰辅酶A</a>→<br /><a href="/wiki/%E7%90%A5%E7%8F%80%E9%85%B0%E8%BE%85%E9%85%B6A" title="琥珀酰辅酶A">琥珀酰辅酶A</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%BC%AC%E6%B0%A8%E9%85%B8" title="缬氨酸">缬氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/%CE%91-%E9%85%AE%E5%BC%82%E6%88%8A%E9%85%B8" title="Α-酮异戊酸">α-酮异戊酸</a></li> <li><a href="/wiki/%E5%BC%82%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A" title="异丁酰辅酶A">异丁酰辅酶A</a></li> <li><a href="/wiki/%E7%94%B2%E5%9F%BA%E4%B8%99%E7%83%AF%E9%85%B0%E8%BE%85%E9%85%B6A" title="甲基丙烯酰辅酶A">甲基丙烯酰辅酶A</a></li> <li><a href="/wiki/3-%E7%BE%9F%E5%BC%82%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A" title="3-羟异丁酰辅酶A">3-羟异丁酰辅酶A</a></li> <li><a href="/wiki/3-%E7%BE%9F%E5%9F%BA%E5%BC%82%E4%B8%81%E9%85%B8" title="3-羟基异丁酸">3-羟基异丁酸</a></li> <li><a href="/wiki/2-%E7%94%B2%E5%9F%BA-3-%E6%B0%A7%E4%BB%A3%E4%B8%99%E9%85%B8" title="2-甲基-3-氧代丙酸">2-甲基-3-氧代丙酸</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E5%BC%82%E4%BA%AE%E6%B0%A8%E9%85%B8" class="mw-redirect" title="异亮氨酸">异亮氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/2,3-%E4%BA%8C%E7%BE%9F%E5%9F%BA-3-%E7%94%B2%E5%9F%BA%E6%88%8A%E9%85%B8" title="2,3-二羟基-3-甲基戊酸">2,3-二羟-3-甲基戊酸</a></li> <li><a href="/wiki/2-%E7%94%B2%E5%9F%BA%E4%B8%81%E9%85%B0%E8%BE%85%E9%85%B6A" title="2-甲基丁酰辅酶A">2-甲基丁酰辅酶A</a></li> <li><a href="/w/index.php?title=%E6%83%95%E6%A0%BC%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="惕格酰辅酶A（页面不存在）">惕格酰辅酶A</a></li> <li><a href="/w/index.php?title=2-%E7%94%B2%E5%9F%BA%E4%B9%99%E9%85%B0%E4%B9%99%E9%85%B0%E8%BE%85%E9%85%B6A&action=edit&redlink=1" class="new" title="2-甲基乙酰乙酰辅酶A（页面不存在）">2-甲基乙酰乙酰辅酶A</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8" title="甲硫氨酸">甲硫氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><i><a href="/wiki/%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8#生成高半胱氨酸" title="甲硫氨酸">生成高半胱氨酸</a>：</i> <a href="/wiki/S-%E8%85%BA%E8%8B%B7%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8" title="S-腺苷甲硫氨酸"><i>S</i>-腺苷甲硫氨酸</a> <ul><li><a href="/wiki/S-%E8%85%BA%E8%8B%B7%E9%AB%98%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="S-腺苷高半胱氨酸"><i>S</i>-腺苷-<small>L</small>-高半胱氨酸</a></li> <li><a class="mw-selflink selflink">高半胱氨酸</a><br /></li></ul> <i><a href="/wiki/%E7%94%B2%E7%A1%AB%E6%B0%A8%E9%85%B8#转变为半胱氨酸" title="甲硫氨酸">转变为半胱氨酸</a>：</i> <a href="/wiki/%E8%83%B1%E7%A1%AB%E9%86%9A" title="胱硫醚">胱硫醚</a>*<a href="/wiki/%CE%91-%E4%B8%81%E9%85%AE%E9%85%B8" title="Α-丁酮酸">α-丁酮酸</a>+<a href="/wiki/%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8" title="半胱氨酸">半胱氨酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%8B%8F%E6%B0%A8%E9%85%B8" class="mw-redirect" title="苏氨酸">苏氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%CE%91-%E4%B8%81%E9%85%AE%E9%85%B8" title="Α-丁酮酸">α-丁酮酸</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E4%B8%99%E9%85%B0%E8%BE%85%E9%85%B6A" title="丙酰辅酶A">丙酰辅酶A</a>→</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E7%94%B2%E5%9F%BA%E4%B8%99%E4%BA%8C%E9%85%B8%E5%8D%95%E9%85%B0%E8%BE%85%E9%85%B6A" title="甲基丙二酸单酰辅酶A">甲基丙二酰辅酶A</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E5%BB%B6%E8%83%A1%E7%B4%A2%E9%85%B8" title="延胡索酸">延胡索酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/%E8%8B%AF%E4%B8%99%E6%B0%A8%E9%85%B8" title="苯丙氨酸">苯丙氨酸</a>→<a href="/wiki/%E9%85%AA%E6%B0%A8%E9%85%B8" title="酪氨酸">酪氨酸</a>→</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/4-%E7%BE%9F%E8%8B%AF%E4%B8%99%E9%85%AE%E9%85%B8" title="4-羟苯丙酮酸">4-羟苯丙酮酸</a></li> <li><a href="/wiki/%E5%B0%BF%E9%BB%91%E9%85%B8" title="尿黑酸">尿黑酸</a></li> <li><a href="/wiki/4-%E9%A9%AC%E6%9D%A5%E9%85%B0%E4%B9%99%E9%85%B0%E4%B9%99%E9%85%B8" title="4-马来酰乙酰乙酸">4-马来酰乙酰乙酸</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">生糖氨基酸→<a href="/wiki/%E8%8D%89%E9%85%B0%E4%B9%99%E9%85%B8" title="草酰乙酸">草酰乙酸</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><i>见<a href="/wiki/%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF" title="尿素循环">尿素循环</a></i></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">其他</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/w/index.php?title=%E5%8D%8A%E8%83%B1%E6%B0%A8%E9%85%B8%E4%BB%A3%E8%B0%A2&action=edit&redlink=1" class="new" title="半胱氨酸代谢（页面不存在）">半胱氨酸代谢</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0px"><div style="padding:0em 0.25em"><a href="/wiki/%E5%8D%8A%E8%83%B1%E4%BA%9A%E7%A3%BA%E9%85%B8" title="半胱亚磺酸">半胱氨酸亚磺酸</a></div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="background: transparent; padding: 0px;"><div></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><td colspan="2" class="navbox-list navbox-odd" style="width:100%;padding:0px;background:transparent;color:inherit;"><div style="padding:0px;"><table class="navbox-columns-table" style="border-spacing: 0px; text-align:left;width:100%;"><tbody><tr style="vertical-align:top;"><td class="navbox-list" style="padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:#ccf;;width:10em;"><div> <p><a href="/wiki/Template:%E5%8C%BB%E5%AD%A6%E5%AF%BC%E8%88%AA" title="Template:医学导航">医学导航</a>：<a href="/wiki/%E9%81%97%E4%BC%A0%E6%80%A7%E4%BB%A3%E8%B0%A2%E7%BC%BA%E9%99%B7" title="遗传性代谢缺陷">遗传代谢缺陷</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:white;;width:10em;"><div> <p><a href="/wiki/Template:%E4%BB%A3%E8%B0%A2" title="Template:代谢">代谢</a>、<a href="/wiki/Template:%E4%B8%89%E7%BE%A7%E9%85%B8%E5%BE%AA%E7%8E%AF%E9%85%B6%E7%B1%BB%E4%B8%8E%E7%94%B5%E5%AD%90%E4%BC%A0%E9%80%92%E9%93%BE" title="Template:三羧酸循环酶类与电子传递链">k</a>,<a href="/wiki/Template:%E7%B3%96%E9%85%B5%E8%A7%A3%E9%85%B6%E7%B1%BB" title="Template:糖酵解酶类">c</a>/<a href="/wiki/Template:%E7%B3%96%E5%8E%9F%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:糖原代谢酶类">g</a>/<a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">r</a>/<a href="/wiki/Template:%E6%88%8A%E7%B3%96%E7%A3%B7%E9%85%B8%E9%80%94%E5%BE%84%E9%85%B6%E7%B1%BB" title="Template:戊糖磷酸途径酶类">p</a>/<a href="/wiki/Template:%E9%86%A3%E8%9B%8B%E7%99%BD%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:醣蛋白代謝酶">y</a>/<a href="/wiki/Template:%E8%9B%8B%E7%99%BD%E8%81%9A%E7%B3%96%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:蛋白聚糖代謝酶">i</a>,<a href="/wiki/Template:%E8%84%82%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:脂代谢酶类">f</a>/<a href="/wiki/Template:%E7%A3%B7%E8%84%82%E4%BB%A3%E8%AC%9D" title="Template:磷脂代謝">h</a>/<a href="/wiki/Template:%E8%86%BD%E5%9B%BA%E9%86%87%E8%88%87%E9%A1%9E%E5%9B%BA%E9%86%87%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:膽固醇與類固醇代謝酶">s</a>/<a href="/wiki/Template:%E8%84%82%E8%9B%8B%E7%99%BD%E4%BB%A3%E8%B0%A2" title="Template:脂蛋白代谢">l</a>/<a href="/wiki/Template:%E7%B3%96%E8%84%82%E8%88%87%E9%9E%98%E8%84%82%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:糖脂與鞘脂代謝酶">o</a>/<a href="/wiki/Template:%E9%A1%9E%E8%8A%B1%E7%94%9F%E9%85%B8%E4%BB%A3%E8%AC%9D%E9%85%B6" title="Template:類花生酸代謝酶">e</a>,<a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:氨基酸代谢酶类">a</a>/<a href="/wiki/Template:%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF%E9%85%B6%E7%B1%BB" title="Template:尿素循环酶类">u</a>,<a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:核苷酸代谢酶类">n</a>,<a href="/wiki/Template:%E5%8D%9F%E5%95%89%E4%BB%A3%E8%B0%A2%E9%85%B6%E7%B1%BB" title="Template:卟啉代谢酶类">m</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:silver;;width:10em;"><div> <p><a href="/wiki/Template:Disorders_of_TCA_and_ETC" class="mw-redirect" title="Template:Disorders of TCA and ETC">k</a>,<a href="/wiki/Template:%E5%85%88%E5%A4%A9%E6%80%A7%E7%B3%96%E7%B1%BB%E4%BB%A3%E8%B0%A2%E7%BC%BA%E9%99%B7" title="Template:先天性糖类代谢缺陷">cgrp</a>/<a href="/wiki/Template:Glycoprotein_disorders" title="Template:Glycoprotein disorders">y</a>/<a href="/w/index.php?title=Template:Proteoglycan_disorders&action=edit&redlink=1" class="new" title="Template:Proteoglycan disorders（页面不存在）">i</a>,<a href="/wiki/Template:Fatty-acid_metabolism_disorders" title="Template:Fatty-acid metabolism disorders">f</a>/<a href="/w/index.php?title=Template:Phospholipid_metabolism_disorders&action=edit&redlink=1" class="new" title="Template:Phospholipid metabolism disorders（页面不存在）">h</a>/<a href="/w/index.php?title=Template:Defects_of_cholesterol_and_steroid_metabolism&action=edit&redlink=1" class="new" title="Template:Defects of cholesterol and steroid metabolism（页面不存在）">s</a>/<a href="/wiki/Template:Lipid_metabolism_disorders" title="Template:Lipid metabolism disorders">l</a>/<a href="/wiki/Template:Lipid_storage_disorders" title="Template:Lipid storage disorders">o</a>/<a href="/wiki/Template:Eicosanoid_metabolism_disorders" title="Template:Eicosanoid metabolism disorders">e</a>,<a href="/wiki/Template:Amino_acid_metabolic_pathology" title="Template:Amino acid metabolic pathology">au</a>,<a href="/w/index.php?title=Template:Inborn_errors_of_purine-pyrimidine_metabolism&action=edit&redlink=1" class="new" title="Template:Inborn errors of purine-pyrimidine metabolism（页面不存在）">n</a>,<a href="/w/index.php?title=Template:Heme_metabolism_disorders&action=edit&redlink=1" class="new" title="Template:Heme metabolism disorders（页面不存在）">m</a>,<a href="/wiki/Template:Eponymous_medical_signs_for_endocrinology,_nutrition,_and_metabolism" title="Template:Eponymous medical signs for endocrinology, nutrition, and metabolism">人名体征</a> </p> </div></td><td class="navbox-list" style="border-left:2px solid #fdfdfd;padding:0px;text-align:center;background:#efefef; font-size:100%;;;text-align:center;background:#ccf;;width:10em;"><div> <p>药物(<a href="/wiki/ATC%E4%BB%A3%E7%A0%81_(A16)" title="ATC代码 (A16)">A16</a>/<a href="/wiki/Template:%E8%A1%80%E8%84%82%E8%B0%83%E8%8A%82%E5%89%82" title="Template:血脂调节剂">C10</a>)、中间产物(<a href="/wiki/Template:%E4%B8%89%E7%BE%A7%E9%85%B8%E5%BE%AA%E7%92%B0" title="Template:三羧酸循環">k</a>,<a href="/wiki/Template:%E7%B3%96%E9%85%B5%E8%A7%A3" title="Template:糖酵解">c</a>/<a href="/wiki/Template:%E7%B3%96%E5%8E%9F%E7%94%9F%E6%88%90%E4%B8%8E%E7%B3%96%E5%8E%9F%E5%88%86%E8%A7%A3%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:糖原生成与糖原分解代谢中间产物">g</a>/<a href="/wiki/Template:%E6%9E%9C%E7%B3%96%E4%B8%8E%E5%8D%8A%E4%B9%B3%E7%B3%96%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:果糖与半乳糖代谢中间产物">r</a>/<a href="/wiki/Template:%E6%88%8A%E7%B3%96%E7%A3%B7%E9%85%B8%E9%80%94%E5%BE%84%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:戊糖磷酸途径中间产物">p</a>/<a href="/wiki/Template:%E7%B3%96%E8%9B%8B%E7%99%BD%E7%B1%BB" title="Template:糖蛋白类">y</a>/<a href="/wiki/Template:%E7%B3%96%E8%83%BA%E8%81%9A%E7%B3%96" title="Template:糖胺聚糖">i</a>,<a href="/wiki/Template:%E8%84%82%E8%82%AA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:脂肪酸代谢中间产物">f</a>/<a href="/wiki/Template:%E7%A3%B7%E8%84%82" title="Template:磷脂">h</a>/<a href="/wiki/Template:%E8%83%86%E5%9B%BA%E9%86%87%E4%B8%8E%E7%94%BE%E4%BD%93%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:胆固醇与甾体中间产物">s</a>/<a href="/wiki/Template:%E9%9E%98%E8%84%82" title="Template:鞘脂">o</a>/<a href="/w/index.php?title=Template:Eicosanoids&action=edit&redlink=1" class="new" title="Template:Eicosanoids（页面不存在）">e</a>,<a href="/wiki/Template:%E6%B0%A8%E5%9F%BA%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:氨基酸代谢中间产物">a</a>/<a href="/wiki/Template:%E5%B0%BF%E7%B4%A0%E5%BE%AA%E7%8E%AF" title="Template:尿素循环">u</a>,<a href="/wiki/Template:%E6%A0%B8%E8%8B%B7%E9%85%B8%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:核苷酸代谢中间产物">n</a>,<a href="/wiki/Template:%E8%A1%80%E7%BA%A2%E7%B4%A0%E4%BB%A3%E8%B0%A2%E4%B8%AD%E9%97%B4%E4%BA%A7%E7%89%A9" title="Template:血红素代谢中间产物">m</a>) </p> </div></td></tr></tbody></table></div></td></tr></tbody></table><div></div><table class="nowraplinks mw-collapsible mw-collapsed navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="col" class="collapsible-title navbox-title" colspan="2"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Template:生物化学物质种类"><abbr title="查看该模板">查</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Template talk:生物化学物质种类"><abbr title="讨论该模板">论</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:%E7%BC%96%E8%BE%91%E9%A1%B5%E9%9D%A2/Template:%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6%E7%89%A9%E8%B4%A8%E7%A7%8D%E7%B1%BB" title="Special:编辑页面/Template:生物化学物质种类"><abbr title="编辑该模板">编</abbr></a></li></ul></div><div id="生物化學物質種類索引" style="font-size:110%;margin:0 5em"><a href="/wiki/%E7%94%9F%E7%89%A9%E5%8C%96%E5%AD%A6" title="生物化学">生物化學物質</a><a href="/wiki/Template:%E4%BB%A3%E8%B0%A2" title="Template:代谢">種類</a>索引</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Template:%E7%B3%96%E7%B1%BB" title="Template:糖类">糖类</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><a href="/wiki/Template:%E9%86%87" title="Template:醇">醇類</a></li> <li><a href="/wiki/Template:%E5%A4%9A%E5%85%83%E9%86%87" title="Template:多元醇">糖醇</a></li> <li><a href="/wiki/Template:%E7%B3%96%E8%9B%8B%E7%99%BD%E7%B1%BB" title="Template:糖蛋白类">醣蛋白</a></li> <li><a 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