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Developers make scientific advancements with the potential to change everything, only to face regulatory conundrums and ever-fluctuating markets. BioWorld tracks key events in the fast-moving sector every business day. Now, the BioWorld Insider podcast lets you hear directly from the movers and shakers whose collective work is changing how we all live. Join us each week for a new conversation.</strong></div></div></div></section> <section class="podcast-file"><article class="podcast-file__article podcast-file__article-index-0"><figure class="podcast-file__image"><a href="/media/podcasts/532-bioworld-insider-podcast/play/52-modifi-gets-creative-on-the-rocky-road-to-a-multibillion-dollar-buyout"><img alt="Ranjit Bindra, co-founder, Modifi" loading="lazy" src="https://www.bioworld.com/ext/resources/Podcast-files/Ranjit-Bindra-co-founder-Modifi-podcast-11-12.jpg?height=150&t=1731434933&width=150" /></a></figure><div class="podcast-file__details -has-image"><h1 class="podcast-file__headline"><a class="podcast-file__headline-link" href="/media/podcasts/532-bioworld-insider-podcast/play/52-modifi-gets-creative-on-the-rocky-road-to-a-multibillion-dollar-buyout">Modifi gets creative on the rocky road to a multibillion-dollar buyout</a></h1><section class="podcast-player"> <a id="podcast52-listen" class="podcast-player__listen-link" data-play-text="Play" data-pause-text="Pause" href="#">Play</a> <div id="podcast52-container" class="podcast-player__container"> <div class="podcast-player__player"> <a id="podcast52" class="podcast-player__file" data-title="Modifi gets creative on the rocky road to a multibillion-dollar buyout" href="//www.bioworld.com/ext/resources/Podcast-files/bioworld_ep46_rx111124_edit1.mp3?1731509899">Listen</a> </div> </div> </section> <div class="podcast-player__listen-container"><div class="podcast-file__duration">Duration: 23:55</div><div class="social-share__wrapper"><a class="podcast-file__share-alt" onclick="toggleSocialShare(0); return false;" href="#"></a><div class="social-share__container" id="social-share__index-0"><section class="social-share" data-url="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/52-modifi-gets-creative-on-the-rocky-road-to-a-multibillion-dollar-buyout" id="social-share__0"><div class="social-share__facebook"></div><div class="social-share__twitter"></div><div class="social-share__reddit"></div><div class="social-share__linkedin"></div></section></div></div></div><div class="podcast-file__released-at">11-12-2024</div><div class="podcast-file__teaser"><p>Modifi Biosciences Inc. was recently acquired by Merck & Co. Inc. for $30 million up front. Modifi shareholders could receive milestones of up to $1.3 billion. It all happened in the dizzyingly short span of a little more than two years. Modifi’s founder, Ranjit Bindra, and a small group of advisers brought the company through preclinical work on DNA repair for treating glioblastoma and then twice faced running out of money and shutting down the company. Confounding the typical wisdom, Bindra and co-founder Kevin Rakin ended up putting the Merck deal together all by themselves. “People would actually ask, ‘Who is your banker that did the M&A deal?’ I said, ‘You're looking at them. It's me and Kevin Rakin.’ I learned a lot.”</p> <p><a href="/ext/resources/Podcast-files/BioWorld-Insider-episode-046-transcript.docx" rel=" noopener noreferrer" target="_blank"><u>Download transcript</u></a></p></div><a class="podcast-file__download-link" href="https://www.bioworld.com/ext/resources/Podcast-files/bioworld_ep46_rx111124_edit1.mp3?1731509899">Download episode</a></div><script>$(function() { window.toggleSocialShare = function (index) { $("#social-share__index-"+index).slideToggle(); }; }); require(['jquery', 'bundle/social-share.bundle'], function($, SocialShare){ $(function() { const count = document.querySelectorAll('.main-body .social-share').length; for (let i = 0; i < count; i++) { new SocialShare.default("#social-share__"+i); } }); });</script></article><article class="podcast-file__article podcast-file__article-index-1"><figure class="podcast-file__image"><a href="/media/podcasts/532-bioworld-insider-podcast/play/53-healing-the-health-divide-for-women"><img alt="Anette Breindl and Karen Carey of BioWorld" loading="lazy" src="https://www.bioworld.com/ext/resources/Podcast-files/Anette-Breindl-Karen-Carey-BW-podcast-Ep-47-11-22.jpg?height=150&t=1732294412&width=150" /></a></figure><div class="podcast-file__details -has-image"><h1 class="podcast-file__headline"><a class="podcast-file__headline-link" href="/media/podcasts/532-bioworld-insider-podcast/play/53-healing-the-health-divide-for-women">Healing the health divide for women</a></h1><section class="podcast-player"> <a id="podcast53-listen" class="podcast-player__listen-link" data-play-text="Play" data-pause-text="Pause" href="#">Play</a> <div id="podcast53-container" class="podcast-player__container"> <div class="podcast-player__player"> <a id="podcast53" class="podcast-player__file" data-title="Healing the health divide for women" href="//www.bioworld.com/ext/resources/Podcast-files/bioworld_ep44_rx211124_edit1.mp3?1732301593">Listen</a> </div> </div> </section> <div class="podcast-player__listen-container"><div class="podcast-file__duration">Duration: 20:53</div><div class="social-share__wrapper"><a class="podcast-file__share-alt" onclick="toggleSocialShare(1); return false;" href="#"></a><div class="social-share__container" id="social-share__index-1"><section class="social-share" data-url="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/53-healing-the-health-divide-for-women" id="social-share__1"><div class="social-share__facebook"></div><div class="social-share__twitter"></div><div class="social-share__reddit"></div><div class="social-share__linkedin"></div></section></div></div></div><div class="podcast-file__released-at">11-22-2024</div><div class="podcast-file__teaser"><p>As a new <em>BioWorld</em> new <a href="https://www.bioworld.com/womens_health">investigative report shows</a>, decades of research excluding women from clinical trials and investment decisions made in male-dominated boardrooms have led to half the world’s health needs being underserved. Of the drug development companies working on women's health solutions, the proportion of funding and partnering for the sector is quite small. But it’s slowly growing, as is the depth of science. Karen Carey, <em>BioWorld</em>’s managing editor and chief analyst, and the managing editor of <em>Bioworld Science</em>, Anette Breindl, join this episode of the <em>BioWorld Insider</em> podcast to talk about the business and the science of women’s health.</p><p><a href="/ext/resources/Podcast-files/BioWorld-Insider-episode-047-transcript.dox.docx" id><u>Download transcript</u></a></p></div><a class="podcast-file__download-link" href="https://www.bioworld.com/ext/resources/Podcast-files/bioworld_ep44_rx211124_edit1.mp3?1732301593">Download episode</a></div><script>$(function() { window.toggleSocialShare = function (index) { $("#social-share__index-"+index).slideToggle(); }; }); require(['jquery', 'bundle/social-share.bundle'], function($, SocialShare){ $(function() { const count = document.querySelectorAll('.main-body .social-share').length; for (let i = 0; i < count; i++) { new SocialShare.default("#social-share__"+i); } }); });</script></article><article class="podcast-file__article podcast-file__article-index-2"><figure class="podcast-file__image"><a href="/media/podcasts/532-bioworld-insider-podcast/play/51-a-quantum-leap-into-the-future-of-drug-development"><img alt="Victoria Lipinska, IBM Quantum " loading="lazy" src="https://www.bioworld.com/ext/resources/Podcast-files/Victoria-Lipinska--IBM-Quantum-podcast-10-17.jpg?height=150&t=1729180017&width=150" /></a></figure><div class="podcast-file__details -has-image"><h1 class="podcast-file__headline"><a class="podcast-file__headline-link" href="/media/podcasts/532-bioworld-insider-podcast/play/51-a-quantum-leap-into-the-future-of-drug-development">A quantum leap into the future of drug development</a></h1><section class="podcast-player"> <a id="podcast51-listen" class="podcast-player__listen-link" data-play-text="Play" data-pause-text="Pause" href="#">Play</a> <div id="podcast51-container" class="podcast-player__container"> <div class="podcast-player__player"> <a id="podcast51" class="podcast-player__file" data-title="A quantum leap into the future of drug development" href="//www.bioworld.com/ext/resources/Podcast-files/bioworld_ep45_rx161024_edit2.mp3?1729180253">Listen</a> </div> </div> </section> <div class="podcast-player__listen-container"><div class="podcast-file__duration">Duration: 17:31</div><div class="social-share__wrapper"><a class="podcast-file__share-alt" onclick="toggleSocialShare(2); return false;" href="#"></a><div class="social-share__container" id="social-share__index-2"><section class="social-share" data-url="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/51-a-quantum-leap-into-the-future-of-drug-development" id="social-share__2"><div class="social-share__facebook"></div><div class="social-share__twitter"></div><div class="social-share__reddit"></div><div class="social-share__linkedin"></div></section></div></div></div><div class="podcast-file__released-at">10-17-2024</div><div class="podcast-file__teaser"><p>In the newest <em>BioWorld Insider</em> podcast, Victoria Lipinska, the America's lead for Quantum Innovation Centers at IBM Quantum, talks about the future of drug development using quantum computing. “The new technology is a completely different branch of computing as opposed to what we know right now, and it's meant to complement what we know, not to really replace it,” she said.</p> <p>Quantum computing could lead to more efficient drug discovery by identifying promising compounds faster, understanding their effects at the molecular level and then reducing the need for costly or time-consuming lab experiments.</p> <p>Lipinska is one of the more than 100 experts who will evaluate the future of health care at the upcoming 2024 <a href="https://biofuture.com/" rel="noopener noreferrer" target="_blank">Biofuture conference</a>. Each year, a group of trailblazers, disruptors and forward-thinking executives converge to evaluate and forecast the future of health care. This year, BioWorld is a sponsor of the Oct. 28-30 event in New York. If you attend, you'll have the chance to hear panels and join workshops and fireside chats with key opinion leaders like Lipinska.</p> <p><a href="/ext/resources/Podcast-files/BioWorld-Insider-episode-045-transcript.docx" rel=" noopener noreferrer" target="_blank"><u>Download transcript</u></a></p></div><a class="podcast-file__download-link" href="https://www.bioworld.com/ext/resources/Podcast-files/bioworld_ep45_rx161024_edit2.mp3?1729180253">Download episode</a></div><script>$(function() { window.toggleSocialShare = function (index) { $("#social-share__index-"+index).slideToggle(); }; }); require(['jquery', 'bundle/social-share.bundle'], function($, SocialShare){ $(function() { const count = document.querySelectorAll('.main-body .social-share').length; for (let i = 0; i < count; i++) { new SocialShare.default("#social-share__"+i); } }); });</script></article><article class="podcast-file__article podcast-file__article-index-3"><figure class="podcast-file__image"><a href="/media/podcasts/532-bioworld-insider-podcast/play/50-gene-and-cell-therapies-will-propel-innovation-says-astellas-cco"><img alt="Claus Zieler, chief commercial officer, Astellas" loading="lazy" src="https://www.bioworld.com/ext/resources/Podcast-files/Claus-Zieler-chief-commercial-officer-Astellas-podcast-10-7.jpg?height=150&t=1728075720&width=150" /></a></figure><div class="podcast-file__details -has-image"><h1 class="podcast-file__headline"><a class="podcast-file__headline-link" href="/media/podcasts/532-bioworld-insider-podcast/play/50-gene-and-cell-therapies-will-propel-innovation-says-astellas-cco">Gene and cell therapies will propel innovation, says Astellas CCO</a></h1><section class="podcast-player"> <a id="podcast50-listen" class="podcast-player__listen-link" data-play-text="Play" data-pause-text="Pause" href="#">Play</a> <div id="podcast50-container" class="podcast-player__container"> <div class="podcast-player__player"> <a id="podcast50" class="podcast-player__file" data-title="Gene and cell therapies will propel innovation, says Astellas CCO" href="//www.bioworld.com/ext/resources/Podcast-files/bioworld_ep44_rx031024_edit1.mp3?1728304441">Listen</a> </div> </div> </section> <div class="podcast-player__listen-container"><div class="podcast-file__duration">Duration: 27:16</div><div class="social-share__wrapper"><a class="podcast-file__share-alt" onclick="toggleSocialShare(3); return false;" href="#"></a><div class="social-share__container" id="social-share__index-3"><section class="social-share" data-url="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/50-gene-and-cell-therapies-will-propel-innovation-says-astellas-cco" id="social-share__3"><div class="social-share__facebook"></div><div class="social-share__twitter"></div><div class="social-share__reddit"></div><div class="social-share__linkedin"></div></section></div></div></div><div class="podcast-file__released-at">10-04-2024</div><div class="podcast-file__teaser"><p>Gene and cell therapies will drive innovation for the next 10 years, Claus Zieler, the chief commercial officer at Astellas Pharma Inc., said in this episode of the <em>BioWorld Insider</em> podcast. Developers are on the cusp of breakthroughs because a gene can now be replaced “and that means we can potentially cure a disease rather than intervening in a disease.” Zieler also shared his thoughts on creating sustainable health care in aging societies, the innovation cycle gap between the U.S. and Europe, and how collaboration between business and government is critical in forging ahead in this wide-ranging discussion.</p> <p><a href="/ext/resources/Podcast-files/Ep-44-BioWorld-Insider-podcast---transcript---final.docx" rel=" noopener noreferrer" target="_blank"><u>Download transcript</u></a></p></div><a class="podcast-file__download-link" href="https://www.bioworld.com/ext/resources/Podcast-files/bioworld_ep44_rx031024_edit1.mp3?1728304441">Download episode</a></div><script>$(function() { window.toggleSocialShare = function (index) { $("#social-share__index-"+index).slideToggle(); }; }); require(['jquery', 'bundle/social-share.bundle'], function($, SocialShare){ $(function() { const count = document.querySelectorAll('.main-body .social-share').length; for (let i = 0; i < count; i++) { new SocialShare.default("#social-share__"+i); } }); });</script></article><article class="podcast-file__article podcast-file__article-index-4"><figure class="podcast-file__image"><a href="/media/podcasts/532-bioworld-insider-podcast/play/49-capricor-s-ceo-pursues-a-bla-and-talks-rare-disease"><img alt="Linda Marbán, CEO, Capricor" loading="lazy" src="https://www.bioworld.com/ext/resources/Podcast-files/Linda-Marbn-CEO-Capricor-9-26-podcast.jpg?height=150&t=1727450141&width=150" /></a></figure><div class="podcast-file__details -has-image"><h1 class="podcast-file__headline"><a class="podcast-file__headline-link" href="/media/podcasts/532-bioworld-insider-podcast/play/49-capricor-s-ceo-pursues-a-bla-and-talks-rare-disease">Capricor’s CEO pursues a BLA and talks rare disease </a></h1><section class="podcast-player"> <a id="podcast49-listen" class="podcast-player__listen-link" data-play-text="Play" data-pause-text="Pause" href="#">Play</a> <div id="podcast49-container" class="podcast-player__container"> <div class="podcast-player__player"> <a id="podcast49" class="podcast-player__file" data-title="Capricor’s CEO pursues a BLA and talks rare disease " href="//www.bioworld.com/ext/resources/Podcast-files/bioworld_ep40_rx250924_edit1.mp3?1727455168">Listen</a> </div> </div> </section> <div class="podcast-player__listen-container"><div class="podcast-file__duration">Duration: 15:49</div><div class="social-share__wrapper"><a class="podcast-file__share-alt" onclick="toggleSocialShare(4); return false;" href="#"></a><div class="social-share__container" id="social-share__index-4"><section class="social-share" data-url="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/49-capricor-s-ceo-pursues-a-bla-and-talks-rare-disease" id="social-share__4"><div class="social-share__facebook"></div><div class="social-share__twitter"></div><div class="social-share__reddit"></div><div class="social-share__linkedin"></div></section></div></div></div><div class="podcast-file__released-at">09-27-2024</div><div class="podcast-file__teaser"><p>Capricor Therapeutics Inc. just wrapped up a visit with the U.S. FDA and is prepping to file a BLA in October for its Duchenne muscular dystrophy treatment. Linda Marbán, Capricor’s CEO, is the guest on the newest BioWorld Insider podcast and she talks about deramiocel (CAP-1002), the company’s allogeneic cardiac-derived cell therapy, for treating the rare disease and how the FDA has made strong efforts in helping lay the groundwork for deramiocel. Marbán has been working on the Duchenne treatment for many years and she has strong insights into how to tackle a rare disease development program and how the FDA has changed its ways over time to help out. She has been in the biopharma space for more than 20 years and also is a co-founder of Capricor. </p> <p><a href="/ext/resources/Podcast-files/Ep-43-BioWorld-Insider-podcast---transcript---final.docx" rel=" noopener noreferrer" target="_blank"><u>Download transcript</u></a></p></div><a class="podcast-file__download-link" href="https://www.bioworld.com/ext/resources/Podcast-files/bioworld_ep40_rx250924_edit1.mp3?1727455168">Download episode</a></div><script>$(function() { window.toggleSocialShare = function (index) { $("#social-share__index-"+index).slideToggle(); }; }); require(['jquery', 'bundle/social-share.bundle'], function($, SocialShare){ $(function() { const count = document.querySelectorAll('.main-body .social-share').length; for (let i = 0; i < count; i++) { new SocialShare.default("#social-share__"+i); } }); });</script></article><article class="podcast-file__article podcast-file__article-index-5"><figure class="podcast-file__image"><a href="/media/podcasts/532-bioworld-insider-podcast/play/48-the-first-half-of-2024-was-strong-as-m-as-and-financings-dominate"><img alt="Karen-Carey,-analyst,-BioWorld-podcast-7-8-.png" loading="lazy" src="https://www.bioworld.com/ext/resources/Podcast-files/Karen-Carey,-analyst,-BioWorld-podcast-7-8-.png?height=150&t=1625780187&width=150" /></a></figure><div class="podcast-file__details -has-image"><h1 class="podcast-file__headline"><a class="podcast-file__headline-link" href="/media/podcasts/532-bioworld-insider-podcast/play/48-the-first-half-of-2024-was-strong-as-m-as-and-financings-dominate">The first half of 2024 was strong as M&As and financings dominate</a></h1><section class="podcast-player"> <a id="podcast48-listen" class="podcast-player__listen-link" data-play-text="Play" data-pause-text="Pause" href="#">Play</a> <div id="podcast48-container" class="podcast-player__container"> <div class="podcast-player__player"> <a id="podcast48" class="podcast-player__file" data-title="The first half of 2024 was strong as M&As and financings dominate" href="//www.bioworld.com/ext/resources/Podcast-files/bioworld_ep39_rx250724-edit1.mp3?1721999314">Listen</a> </div> </div> </section> <div class="podcast-player__listen-container"><div class="podcast-file__duration">Duration: 18:00</div><div class="social-share__wrapper"><a class="podcast-file__share-alt" onclick="toggleSocialShare(5); return false;" href="#"></a><div class="social-share__container" id="social-share__index-5"><section class="social-share" data-url="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/48-the-first-half-of-2024-was-strong-as-m-as-and-financings-dominate" id="social-share__5"><div class="social-share__facebook"></div><div class="social-share__twitter"></div><div class="social-share__reddit"></div><div class="social-share__linkedin"></div></section></div></div></div><div class="podcast-file__released-at">07-25-2024</div><div class="podcast-file__teaser"><p>Karen Carey, <em>BioWorld</em> managing editor and chief analyst, takes a look at the numbers from the first half of 2024. She finds the first six months to be healthy for the biopharma market while the rest of the year is populated with question marks that include the U.S. presidential election and potential interest rate cuts. </p> <p><a href="/ext/resources/Podcast-files/Ep-41-BioWorld-Insider-podcast---transcript---final.docx" rel=" noopener noreferrer" target="_blank"><u>Download transcript</u></a></p></div><a class="podcast-file__download-link" href="https://www.bioworld.com/ext/resources/Podcast-files/bioworld_ep39_rx250724-edit1.mp3?1721999314">Download episode</a></div><script>$(function() { window.toggleSocialShare = function (index) { $("#social-share__index-"+index).slideToggle(); }; }); require(['jquery', 'bundle/social-share.bundle'], function($, SocialShare){ $(function() { const count = document.querySelectorAll('.main-body .social-share').length; for (let i = 0; i < count; i++) { new SocialShare.default("#social-share__"+i); } }); });</script></article><article class="podcast-file__article podcast-file__article-index-6"><figure class="podcast-file__image"><a href="/media/podcasts/532-bioworld-insider-podcast/play/47-the-cost-of-delays-in-development-and-sales-it-s-probably-not-what-you-think"><img alt="Ken Getz, executive director and professor, Center for the Study of Drug Development, Tufts University School of Medicine" loading="lazy" src="https://www.bioworld.com/ext/resources/Podcast-files/Ken-Getz-executive-director-and-professor-Center-for-the-Study-of-Drug-Development-Tufts-University-School-of-Medicine_podcast-7-17.jpg?height=150&t=1721231799&width=150" /></a></figure><div class="podcast-file__details -has-image"><h1 class="podcast-file__headline"><a class="podcast-file__headline-link" href="/media/podcasts/532-bioworld-insider-podcast/play/47-the-cost-of-delays-in-development-and-sales-it-s-probably-not-what-you-think">The cost of delays in development and sales: It’s probably not what you think</a></h1><section class="podcast-player"> <a id="podcast47-listen" class="podcast-player__listen-link" data-play-text="Play" data-pause-text="Pause" href="#">Play</a> <div id="podcast47-container" class="podcast-player__container"> <div class="podcast-player__player"> <a id="podcast47" class="podcast-player__file" data-title="The cost of delays in development and sales: It’s probably not what you think" href="//www.bioworld.com/ext/resources/Podcast-files/bioworld_ep38_rx160724_edit1.mp3?1721232182">Listen</a> </div> </div> </section> <div class="podcast-player__listen-container"><div class="podcast-file__duration">Duration: 16:43</div><div class="social-share__wrapper"><a class="podcast-file__share-alt" onclick="toggleSocialShare(6); return false;" href="#"></a><div class="social-share__container" id="social-share__index-6"><section class="social-share" data-url="https://www.bioworld.com/media/podcasts/532-bioworld-insider-podcast/play/47-the-cost-of-delays-in-development-and-sales-it-s-probably-not-what-you-think" id="social-share__6"><div class="social-share__facebook"></div><div class="social-share__twitter"></div><div class="social-share__reddit"></div><div class="social-share__linkedin"></div></section></div></div></div><div class="podcast-file__released-at">07-17-2024</div><div class="podcast-file__teaser"><p>Two costs of developing drug candidates have been upended by new research from the Tufts University School of Medicine’s Center for the Study of Drug Development. New data have produced some very different numbers than you might expect in the cost of a single day of a clinical trial and of missing a day to generate prescription drugs sales. The center’s director, Ken Getz, spoke to the <em>BioWorld Insider</em> podcast about updating the outdated numbers and what it means for companies and investors.</p> <p><a href="/ext/resources/Podcast-files/Ep-40-BioWorld-Insider-podcast---transcript---final.docx" rel=" noopener noreferrer" target="_blank"><u>Download transcript</u></a></p></div><a class="podcast-file__download-link" href="https://www.bioworld.com/ext/resources/Podcast-files/bioworld_ep38_rx160724_edit1.mp3?1721232182">Download episode</a></div><script>$(function() { window.toggleSocialShare = function (index) { $("#social-share__index-"+index).slideToggle(); }; }); require(['jquery', 'bundle/social-share.bundle'], function($, SocialShare){ $(function() { const count = document.querySelectorAll('.main-body .social-share').length; for (let i = 0; i < count; i++) { new SocialShare.default("#social-share__"+i); } }); });</script></article></section> <nav class="podcasts-more-links"> <a 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