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href="/web/20111210084333/http://www.ncbi.nlm.nih.gov/genome/guide/zebrafish/" class="section_link">Danio rerio</a><br/></p></div></div></td><td><img src="/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/corehtml/transparent.gif" width="20" height="1" border="0"/></td></tr></table></td>  <td valign="top" width="100%"> <table id="ResultPanel" border="0" cellspacing="0" cellpadding="0" width="100%" height="100%"> <tr> <td><img src="/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/corehtml/transparent.gif" height="4" border="0"/></td> </tr> <tr> <td>  <div><noscript> <p class="nojs"> <strong>Warning:</strong> The NCBI web site requires JavaScript to function. <a href="https://web.archive.org/web/20111210084333/http://www.ncbi.nlm.nih.gov/corehtml/query/static/unsupported-browser.html#enablejs" title="Learn how to enable JavaScript" target="_blank">more...</a> </p> </noscript><div id="pink_msg" class="messagebars"><div>Your browser version may not work well with NCBI's Web 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More information <a href="/web/20111210084333/http://www.ncbi.nlm.nih.gov/corehtml/query/static/unsupported-browser.html">here...</a></div></div></div> </td> </tr> <tr>   <td width="100%" bgcolor="#FFFFFF">  <div><input name="EntrezSystem2.PEntrez.Homologene.Homologene_ResultsPanel.Homologene_DisplayBar.LastPresentation" sid="1" type="hidden" value="DocSum"/><input name="EntrezSystem2.PEntrez.Homologene.Homologene_ResultsPanel.Homologene_DisplayBar.Presentation" sid="1" type="hidden" value="DocSum"/><input name="EntrezSystem2.PEntrez.Homologene.Homologene_ResultsPanel.Homologene_DisplayBar.PageSize" sid="1" type="hidden" value="20"/><input name="EntrezSystem2.PEntrez.Homologene.Homologene_ResultsPanel.Homologene_DisplayBar.Sort" sid="1" type="hidden" value=""/><input name="EntrezSystem2.PEntrez.Homologene.Homologene_ResultsPanel.Homologene_DisplayBar.SendTo" sid="1" type="hidden" value=""/></div>   <table> <tr> <td width="70%">  <div portlet="ResultsPanel.ResultsSearchController"><span> <p class="bodytext">HomoloGene is a system for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes.</p> <table class="welcome"><tr><td width="450"> <table width="450" cellspacing="0" cellpadding="0"> <tr><td valign="top" colspan="5" width="450"><span class="graybannertext">HomoloGene Release 65 Statistics</span><br></br><img alt="" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/darkgray.gif" width="450" height="1"/><br></br> <span class="bodytext"> Initial numbers of genes from complete genomes, numbers of genes placed in a homology group, and the numbers of groups for each species.</span> <br></br><img alt="" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/darkgray.gif" width="450" height="1"/></td></tr> <tr> <td class="grayboldtext" valign="bottom" width="220">Species</td> <td class="grayboldtext" colspan="3" align="center" valign="bottom" width="150"><u>聽 Number of Genes 聽 </u></td> <td class="grayboldtext" valign="bottom" align="right" width="75">HomoloGene</td> </tr> <tr><td class="grayboldtext" valign="bottom" width="speciescol">聽</td> <td class="grayboldtext" valign="bottom" align="right" width="60">Input</td> <td class="grayboldtext" valign="bottom" align="right" width="70">Grouped</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="grayboldtext" valign="bottom" align="right" width="75">groups</td> </tr> <tr> <td colspan="5" width="450"><img alt="" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/darkgray.gif" width="450" height="1"/></td></tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Homo sapiens</td> <td class="bodytext" align="right" width="60">19,943<sup>*</sup></td> <td class="bodytext" align="right" width="70">18,981</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">18,431</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Pan troglodytes</td> <td class="bodytext" align="right" width="60">25,096<sup>聽</sup></td> <td class="bodytext" align="right" width="70">16,850</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">15,980</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Canis familiaris</td> <td class="bodytext" align="right" width="60">19,766<sup>聽</sup></td> <td class="bodytext" align="right" width="70">16,708</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">15,951</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Bos taurus</td> <td class="bodytext" align="right" width="60">22,049<sup>聽</sup></td> <td class="bodytext" align="right" width="70">18,180</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">16,224</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Mus musculus</td> <td class="bodytext" align="right" width="60">25,388<sup>聽</sup></td> <td class="bodytext" align="right" width="70">21,766</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">19,005</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Rattus norvegicus</td> <td class="bodytext" align="right" width="60">21,991<sup>聽</sup></td> <td class="bodytext" align="right" width="70">19,229</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">17,473</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Gallus gallus</td> <td class="bodytext" align="right" width="60">17,959<sup>聽</sup></td> <td class="bodytext" align="right" width="70">13,142</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">11,905</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Danio rerio</td> <td class="bodytext" align="right" width="60">26,690<sup>*</sup></td> <td class="bodytext" align="right" width="70">21,084</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">14,067</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Drosophila melanogaster</td> <td class="bodytext" align="right" width="60">13,827<sup>*</sup></td> <td class="bodytext" align="right" width="70">9,282</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">7,749</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Anopheles gambiae</td> <td class="bodytext" align="right" width="60">12,460<sup>聽</sup></td> <td class="bodytext" align="right" width="70">8,867</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">7,541</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Caenorhabditis elegans</td> <td class="bodytext" align="right" width="60">20,132<sup>*</sup></td> <td class="bodytext" align="right" width="70">8,678</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">4,810</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Schizosaccharomyces pombe</td> <td class="bodytext" align="right" width="60">5,043<sup>聽</sup></td> <td class="bodytext" align="right" width="70">3,225</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">2,935</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Saccharomyces cerevisiae</td> <td class="bodytext" align="right" width="60">5,880<sup>聽</sup></td> <td class="bodytext" align="right" width="70">4,851</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">4,370</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Kluyveromyces lactis</td> <td class="bodytext" align="right" width="60">5,335<sup>聽</sup></td> <td class="bodytext" align="right" width="70">4,459</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">4,382</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Eremothecium gossypii</td> <td class="bodytext" align="right" width="60">4,722<sup>聽</sup></td> <td class="bodytext" align="right" width="70">3,928</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">3,884</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Magnaporthe grisea</td> <td class="bodytext" align="right" width="60">12,832<sup>聽</sup></td> <td class="bodytext" align="right" width="70">7,330</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">6,399</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Neurospora crassa</td> <td class="bodytext" align="right" width="60">9,821<sup>*</sup></td> <td class="bodytext" align="right" width="70">6,287</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">6,144</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Arabidopsis thaliana</td> <td class="bodytext" align="right" width="60">27,309<sup>*</sup></td> <td class="bodytext" align="right" width="70">19,961</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">11,243</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Oryza sativa</td> <td class="bodytext" align="right" width="60">26,887<sup>聽</sup></td> <td class="bodytext" align="right" width="70">17,276</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">10,627</td> </tr> <tr><td class="bodytext" nowrap="nowrap" width="220">Plasmodium falciparum</td> <td class="bodytext" align="right" width="60">5,266<sup>聽</sup></td> <td class="bodytext" align="right" width="70">1,862</td> <td class="grayboldtext" valign="bottom" align="right" width="20">聽</td> <td class="bodytext" align="right" width="75">799</td> </tr> <tr><td colspan="5" width="450"><img alt="" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/darkgray.gif" width="450" height="1"/><span class="smalltext"><br></br>'*' indicates organisms where new genome annotation data is used in this build. </span><br></br><span class="smalltext">Last updated on: Mon Feb 14 2011 </span><br></br> <span class="bodytext"><br></br>We have recently adopted a new build procedure that makes use of amino acid sequence searching (blastp) to find more distant relationships, but the procedure still refers to the DNA sequence for computation of some of the statistics. The matching strategy is guided by the taxonomic tree such that more closely related organisms are compared first. Moreover, HomoloGene entries now include paralogs in addition to orthologs.</span><br></br><br></br><span class="graybannertext">Sources of Additional Information</span><br></br><img alt="" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/darkgray.gif" width="450" height="1"/><br></br><span class="bodytext">HomoloGene entries have been augumented with homology and phenotype information drawn from the following sources.</span><br></br><a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://www.ncbi.nlm.nih.gov/omim/"> Online Mendelian Inheritance in Man (OMIM)</a><br></br> <a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://www.informatics.jax.org/"> Mouse Genome Informatics (MGI)</a><br></br> <a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://www.zfin.org/"> Zebrafish Information Network (ZFIN)</a><br></br> <a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://genome-www.stanford.edu/Saccharomyces/"> Saccharomyces Genome Database (SGD)</a><br></br> <a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://flybase.bio.indiana.edu/"> FlyBase</a><br></br> </td></tr> </table>  </td> <td width="50">聽</td> <td valign="top" width="250"><br></br> <table border="1" width="225" cellspacing="2" cellpadding="2" valign="top"> <tr> <td bgcolor="ffffff" valign="top" style="border-top:0;border-left:0;border-bottom:0;border-right:0"> <div width="225" align="center"><font class="graybannertext">What's New</font></div> </td></tr></table> <table border="0" width="225" cellspacing="2" cellpadding="2" valign="top"> <tr> <td> <font class="bodytext"> HomoloGene release 65 includes updated annotations for the following species: Homo sapiens (NCBI release 37.2), Danio rerio (NCBI release 4.1), Drosophila melanogaster (NCBI release 9.3) Caenorhabditis elegans (NCBI release 9.1), Arabidopsis thaliana (NCBI release 9.1).<br/><br/></font> </td> </tr> </table><br></br> <table border="1" width="225" cellspacing="2" cellpadding="2" valign="top"> <tr> <td bgcolor="ffffff" valign="top" style="border-top:0;border-left:0;border-bottom:0;border-right:0"> <div width="225" align="center"><font class="graybannertext">Related Resources</font></div> </td></tr></table> <table border="1" width="225" cellspacing="2" cellpadding="2" valign="top"> <tr> <td bgcolor="E4E7E9" valign="top" style="border-top:0;border-left:0;border-bottom:0;border-right:0"> <div width="225"><font class="heading2">Entrez Genomes</font></div> <font class="smalltext">A collection of complete genome sequences that includes more than 1000 viruses and over hundred microbes</font><br></br> <a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://www.ncbi.nlm.nih.gov/genomes/static/a.html">聽<img alt="" border="0" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/orange.gif" width="5" height="5"/> Archaea</a><br></br><a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://www.ncbi.nlm.nih.gov/genomes/static/eub.html"> 聽<img alt="" border="0" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/orange.gif" width="5" height="5"/> Bacteria</a><br></br> <a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://www.ncbi.nlm.nih.gov/genomes/static/euk.html"> 聽<img alt="" border="0" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/orange.gif" width="5" height="5"/> Eukaryota</a><br></br> <a class="intextlinks" href="https://web.archive.org/web/20111210084333/http://www.ncbi.nlm.nih.gov/genomes/static/vis.html"> 聽<img alt="" border="0" src="https://web.archive.org/web/20111210084333im_/http://www.ncbi.nlm.nih.gov/genome/guide/corehtml/orange.gif" width="5" height="5"/> Viruses</a><br></br> </td></tr></table><br></br> </td></tr></table> <p>聽</p><p>聽</p><p>聽</p><p>聽</p><p>聽</p><p>聽</p></span></div>   </td> <td width="30%" valign="top"> </td> </tr> </table>    </td> </tr> </table> </td> </tr> </table>  <table id="footer" align="center"> <tr valign="bottom" align="center"> <td width="100%"> <br/>  <div id="Footer"> <ul id="footerlist"> <li> <a xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" href="/web/20111210084333/http://www.ncbi.nlm.nih.gov/sites/ehelp?Ncbi_App=entrez&Db=homologene&Page=Home&Time=2011-12-10T03:43:33-05:00&Host=portal206&Snapshot=/projects/entrez/Entrez@4.493" 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