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Pistol</title> <meta name="description" content="Search results for: Gina C. Pistol"> <meta name="keywords" content="Gina C. Pistol"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="Gina C. 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Pistol"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 32</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Gina C. Pistol</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">32</span> Aporia, Daze and Arcanes during Visit to Scene of Crime: A Case History</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20S.%20Grewal">A. S. Grewal</a>, <a href="https://publications.waset.org/abstracts/search?q=Sh.%20Dharambir"> Sh. Dharambir</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20S.%20Sangwan"> R. S. Sangwan</a>, <a href="https://publications.waset.org/abstracts/search?q=Vikas%20Dhanda"> Vikas Dhanda </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Every Scene of Crime is of different kind in nature. Sometimes we see such type of circumstances that we become confused to judge whether the case is of homicide or suicide. In such circumstances a doyen is asked for the option. On the basis of his esoteric knowledge he finds such clues which force the sleuth to change the under sections of Indian penal Code. Here we have examined a case by visiting Scene of Crime and found that a person was found lying dead in a room. There was only one passage which was found opened, the pistol along with the fired cartridge case, misfired cartridge were lying on the spot. Observation method, mathematical calculations, chemical examination and other aspects were considered. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=country-made%20pistol" title="country-made pistol">country-made pistol</a>, <a href="https://publications.waset.org/abstracts/search?q=misfired%20cartridge" title=" misfired cartridge"> misfired cartridge</a>, <a href="https://publications.waset.org/abstracts/search?q=fired%20cartridge%20case" title=" fired cartridge case"> fired cartridge case</a>, <a href="https://publications.waset.org/abstracts/search?q=blackening" title=" blackening"> blackening</a>, <a href="https://publications.waset.org/abstracts/search?q=nitrite" title=" nitrite"> nitrite</a> </p> <a href="https://publications.waset.org/abstracts/7867/aporia-daze-and-arcanes-during-visit-to-scene-of-crime-a-case-history" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7867.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">396</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">31</span> Effect of Xenobiotic Bioactive Compounds from Grape Waste on Inflammation and Oxidative Stress in Pigs</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ionelia%20Taranu">Ionelia Taranu</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Cecilia%20Pistol"> Gina Cecilia Pistol</a>, <a href="https://publications.waset.org/abstracts/search?q=Mihai%20Alexandru%20Gras"> Mihai Alexandru Gras</a>, <a href="https://publications.waset.org/abstracts/search?q=Mihai%20Laurentiu%20Palade"> Mihai Laurentiu Palade</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariana%20Stancu"> Mariana Stancu</a>, <a href="https://publications.waset.org/abstracts/search?q=Veronica%20Sanda%20Chedea"> Veronica Sanda Chedea</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the last decade bioactive compounds from grape waste are investigated as new therapeutic agents for the inhibition of carcinogenesis and other diseases. The objective of this study was to characterize several bioactive compounds (polyphenols and polyunsaturated fatty acids) of a dried grape pomace (GP) derived from a Romanian winery and further to evaluate their effect on inflammation and oxidative markers in liver of pig used as animal model. The total polyphenol concentration of pomace was 36.2g gallic acid equiv /100g. The pomace was rich in polyphenols from the flavonoids group, the main class being flavanols (epicatechins, catechin, epigallocatechin, procyanidins) and antocyanins (Malvidin 3-O-glucoside). The highest concentration was recorded for epicatechin (51.96g/100g) and procyanidin dimer (22.79g/100g). A high concentration of total polyunsaturated fatty acids (PUFA) especially ω-6 fatty acids (59.82 g/100g fat) was found in grape pomace. 20 crossbred TOPIG hybrid fattening pigs were randomly assigned (n = 10) to two experimental treatments: a normal diet (control group) and a diet included 5% grape pomace (GP group) for 24 days. The GP diet lowered the gene expression and protein concentration of IL-1β, IL-8, TNF-α and IFN-γ cytokines in liver suggesting an anti-inflammatory effect of GP diet. Concentration of hepatic TBARS also decreased, but the total antioxidant capacity (liver TEAC) and activity and gene expression of antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase) did not differ between the GP and control diet. The results showed that GP diet exerted an anti-inflammatory effect, but the 5% dietary inclusion modulated only partially the oxidative stress. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=animal%20model" title="animal model">animal model</a>, <a href="https://publications.waset.org/abstracts/search?q=inflammation" title=" inflammation"> inflammation</a>, <a href="https://publications.waset.org/abstracts/search?q=grape%20waste" title=" grape waste"> grape waste</a>, <a href="https://publications.waset.org/abstracts/search?q=immune%20organs" title=" immune organs"> immune organs</a> </p> <a href="https://publications.waset.org/abstracts/68317/effect-of-xenobiotic-bioactive-compounds-from-grape-waste-on-inflammation-and-oxidative-stress-in-pigs" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68317.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">339</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">30</span> The Modulation of Health and Inflammatory Status in Young Pigs by Grape Waste Enriched in Polyphenols</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gina%20Cecilia%20Pistol">Gina Cecilia Pistol</a>, <a href="https://publications.waset.org/abstracts/search?q=Loredana%20Calin"> Loredana Calin</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariana%20%20Stancu"> Mariana Stancu</a>, <a href="https://publications.waset.org/abstracts/search?q=Veronica%20Chedea"> Veronica Chedea</a>, <a href="https://publications.waset.org/abstracts/search?q=Ionelia%20Taranu"> Ionelia Taranu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Inflammatory-associated diseases have an increased trend in the past decades. The pharmacological strategies aimed to treat these inflammatory diseases are very expensive and with non-beneficial results. The current trend is to find alternative strategies to counteract or to control inflammatory component of diseases. The grape by-products either seeds or pomace are rich in bioactive compounds (e.g. polyphenols) which may be beneficial in prevention of inflammation associated with cancer progression and other pathologies with inflammatory component. The in vivo models are very useful for studying the immune and inflammatory status. The domestic pig (Sus scrofa domesticus) is related to human from anatomic and physiologic point of view, representing a feasible model for studying the human inflammatory pathologies. Starting from these data, we evaluated the effect of a diet containing 5% grape seed cakes (GS) on piglets blood biochemical parameters and immune pro- and anti-inflammatory biomarkers (IL-1 beta, IL-8, TNF-alpha, IL-6, IFN-gamma, IL-10, IL-4) in spleen and lymph nodes. 12 weaned piglets were fed for 30 days with a control diet or an experimental diet containing 5% GS. At the end of trial, plasma and tissue samples (spleen and lymph nodes) were collected and the biochemical and inflammatory markers were analysed by using biochemistry analyser and ELISA techniques. Our results showed that diet included 5% GS did not influence the health status determined by plasma biochemical parameters. Only a tendency for a slight increase of the biochemical parameters associated with energetic profile (glucose, cholesterol, triglycerides) was observed. Also, GS diet had no effect on pro- and anti-inflammatory cytokines content in spleen and lymph nodes tissue. Further experiments are needed in order to investigate other rate of dietary inclusion which could provide more evidence about the effect of grape bioactive compounds on pigs used as animal model. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=animal%20model" title="animal model">animal model</a>, <a href="https://publications.waset.org/abstracts/search?q=inflammation" title=" inflammation"> inflammation</a>, <a href="https://publications.waset.org/abstracts/search?q=grape%20seed%20by-product" title=" grape seed by-product"> grape seed by-product</a>, <a href="https://publications.waset.org/abstracts/search?q=immune%20organs" title=" immune organs"> immune organs</a> </p> <a href="https://publications.waset.org/abstracts/67595/the-modulation-of-health-and-inflammatory-status-in-young-pigs-by-grape-waste-enriched-in-polyphenols" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67595.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">290</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">29</span> Use of Pig as an Animal Model for Assessing the Differential MicroRNA Profiling in Kidney after Aristolochic Acid Intoxication</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Daniela%20E.%20Marin">Daniela E. Marin</a>, <a href="https://publications.waset.org/abstracts/search?q=Cornelia%20Braicu"> Cornelia Braicu</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20C.%20Pistol"> Gina C. Pistol</a>, <a href="https://publications.waset.org/abstracts/search?q=Roxana%20Cojocneanu-Petric"> Roxana Cojocneanu-Petric</a>, <a href="https://publications.waset.org/abstracts/search?q=Ioana%20Berindan%20Neagoe"> Ioana Berindan Neagoe</a>, <a href="https://publications.waset.org/abstracts/search?q=Mihail%20A.%20Gras"> Mihail A. Gras</a>, <a href="https://publications.waset.org/abstracts/search?q=Ionelia%20Taranu"> Ionelia Taranu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aristolochic acid (AA) is a carcinogenic, mutagenic, and nephrotoxic compound commonly found in the Aristolochiaceae family of plants. AA is frequently associated with urothelial carcinoma of the upper urinary tract in human and animals and is considered as being responsible for Balkan Endemic Nephropathy. The pig provides a good animal model because the porcine urological system is very similar to that of humans, both in aspects of physiology and anatomy. MicroRNA (miRNA) are small non-coding RNAs that have an impact on a wide range of biological processes by regulating gene expression at post-transcriptional level. The objective of this study was to analyze the miRNA profiling in the kidneys of AA intoxicated swine. For this purpose, ten TOPIGS-40 crossbred weaned piglets, 4-week-old, male and females with an initial average body weight of 9.83 ± 0.5 kg were studied for 28 days. They were given ad libitum access to water and feed and randomly allotted to one of the following groups: control group (C) or aristolochic acid group (AA). They were fed a maize-soybean-meal-based diet contaminated or not with 0.25mgAA/kg. To profile miRNA in the kidneys of pigs, microarrays and bioinformatics approaches were applied to analyze the miRNA in the kidney of control and AA intoxicated pigs. After normalization, our results have shown that a total of 5 known miRNAs and 4 novel miRNAs had different profiling in the kidney of intoxicated animals versus control ones. Expression of miR-32-5p, miR-497-5p, miR-423-3p, miR-218-5p, miR-128-3p were up-regulated by 0.25mgAA/kg feed, while the expression of miR-9793-5p, miR-9835-3p, miR-9840-3p, miR-4334-5p was down-regulated. The microRNA profiling in kidney of intoxicated animals was associated with modified expression of target genes as: RICTOR, LASP1, SFRP2, DKK2, BMI1, RAF1, IGF1R, MAP2K1, WEE1, HDGF, BCL2, EIF4E etc, involved in cell division cycle, apoptosis, cell differentiation and cell migration, cell signaling, cancer etc. In conclusion, this study provides new data concerning the microRNA profiling in kidney after aristolochic acid intoxications with important implications for human and animal health. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aristolochic%20acid" title="aristolochic acid">aristolochic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney" title=" kidney"> kidney</a>, <a href="https://publications.waset.org/abstracts/search?q=microRNA" title=" microRNA"> microRNA</a>, <a href="https://publications.waset.org/abstracts/search?q=swine" title=" swine"> swine</a> </p> <a href="https://publications.waset.org/abstracts/67527/use-of-pig-as-an-animal-model-for-assessing-the-differential-microrna-profiling-in-kidney-after-aristolochic-acid-intoxication" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67527.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">283</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">28</span> The Effects of Grape Waste Bioactive Compounds on the Immune Response and Oxidative Stress in Pig Kidney</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mihai%20Palade">Mihai Palade</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Cecilia%20Pistol"> Gina Cecilia Pistol</a>, <a href="https://publications.waset.org/abstracts/search?q=Mariana%20%20Stancu"> Mariana Stancu</a>, <a href="https://publications.waset.org/abstracts/search?q=Veronica%20Chedea"> Veronica Chedea</a>, <a href="https://publications.waset.org/abstracts/search?q=Ionelia%20Taranu"> Ionelia Taranu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nutrition is an important determinant of general health status, with especially focus on prevention and/or attenuation of the inflammatory-associated pathologies. People with chronic kidney disease can experience chronic inflammation that can lead to cardiovascular disease and even an increased rate of death. There are important links between chronic kidney diseases, inflammation and nutritional strategies that may prevent or protect against undesirable inflammation and oxidative stress. The grape by-products either seeds or pomace are rich in polyphenols which may be beneficial in prevention of inflammatory, antioxidant and antimicrobial processes. As a model for studying the impact of grape seeds on renal inflammation and oxidative stress, we used in this study weaned piglets. After a feeding trial of 30 days with a control diet and an experimental diet containing 5% grape seed (GS), kidney samples were collected. In renal tissues were determined the expression and activity of important markers of immune respose and oxidative stress: pro-inflammatory cytokines (TNF-alpha, IL-1 beta, IL-6, IL-8, IFN-gamma), anti-inflammatory cytokines (IL-4, IL-10), anti-oxidant enzymes (catalase CAT, superoxide dismutase SOD, glutathione peroxidise GPx) and important mediators belonging to nuclear receptors (NF-kB1, Nrf-2 and PPAR-gamma). Gene expression was evaluated by qPCR, whereas protein concentration was determined using proteomic techniques (ELISA). The activity of anti-oxidant enzymes was determined using specific kits. Our results showed that GS enriched in polyphenols does not have effect on TNF-alpha, IL-6 and IL-1 beta gene expression and protein concentration in kidney. By contrast, the gene expression and protein level of IL-8 and IFN-gamma were decreased in GS kidney. Anti-inflammatory cytokines IL-4 and IL-10 gene levels were increased in kidneys collected from GS piglets in comparison with controls, with no modification of protein levels between the two groups. The activities of anti-oxidant enzymes CAT and GPx were increased in kidney by GS, whereas SOD activity was unmodified in comparison with control samples. Also, the GS diet was associated with no modulation of mRNAs for nuclear receptors NF-kB1, Nrf-2 and PPAR-gamma gene expressions in kidneys. In conclusion, our results demonstrated that GS enriched in bioactive compounds such polyphenols could modulate inflammation and oxidative stress markers in kidney tissues. Further studies are necessary to elucidate the mechanism of action of GS compounds in case kidney inflammation associated with oxidative stress, and signalling molecules involved in these mechanisms. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=animal%20model" title="animal model">animal model</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20inflammation" title=" kidney inflammation"> kidney inflammation</a>, <a href="https://publications.waset.org/abstracts/search?q=oxidative%20stress" title=" oxidative stress"> oxidative stress</a>, <a href="https://publications.waset.org/abstracts/search?q=grape%20seed" title=" grape seed"> grape seed</a> </p> <a href="https://publications.waset.org/abstracts/67598/the-effects-of-grape-waste-bioactive-compounds-on-the-immune-response-and-oxidative-stress-in-pig-kidney" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/67598.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">298</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">27</span> Assessment of Online Web-Based Learning for Enhancing Student Grades in Chemistry</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ian%20Marc%20Gealon%20Cabugsa">Ian Marc Gealon Cabugsa</a>, <a href="https://publications.waset.org/abstracts/search?q=Eleanor%20Pastrano%20Corcino"> Eleanor Pastrano Corcino</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Lapaza%20Montalan"> Gina Lapaza Montalan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study focused on the effect of Online Web-Learning (OWL) in the performance of the freshmen Civil Engineering Students of Ateneo de Davao University in their Chem 12 subject. The grades of the students that were required to use OWL were compared to students without OWL. The result of the study suggests promising result for the use of OWL in increasing the performance rate of students taking up Chem 12. Furthermore, there was a positive correlation between the final grade and OWL grade of the students that had OWL. While the majority of the students find OWL to be helpful in supporting their chemistry knowledge needs, most of them still prefer to learn using the traditional face-to-face instruction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chemistry%20education" title="chemistry education">chemistry education</a>, <a href="https://publications.waset.org/abstracts/search?q=enhanced%20performance" title=" enhanced performance"> enhanced performance</a>, <a href="https://publications.waset.org/abstracts/search?q=engineering%20chemistry" title=" engineering chemistry"> engineering chemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=online%20web-based%20learning" title=" online web-based learning"> online web-based learning</a> </p> <a href="https://publications.waset.org/abstracts/33395/assessment-of-online-web-based-learning-for-enhancing-student-grades-in-chemistry" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33395.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">374</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">26</span> Characteristics Features and Action Mechanism of Some Country Made Pistols</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ajitesh%20Pal">Ajitesh Pal</a>, <a href="https://publications.waset.org/abstracts/search?q=Arpan%20Datta%20Roy"> Arpan Datta Roy</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20K.%20Pratihari"> H. K. Pratihari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The different illegal firearms crudely made by skilled gunsmith from scrap materials are popularly known as country made firearms. Such firearms along with improvised ammunition are clandestinely marketed at the cheaper price without any license to the extremist group, criminal, poachers and firearm lovers. As per National Crime Records Bureau (NCRB), MHA, Govt of India about 80% firearm cases are committed by country made/improvised firearms. The ballistic division of the laboratory has examined a good number of cases. The analysis of firearm cases received for forensic examination revealed that 7.65mm calibre pistols mostly improvised firearm are commonly used in firearm related crime cases. In the present communication, physical parameters and other characteristics features of some 7.65mm calibre pistols have been discussed in detail. The detailed study on country made (CM) firearm will help to prepare a database related to type of material used, origin of the raw material and tools used for inscription. The study also includes to establish the chemistry of propellants & head stamp pattern. The database will be helpful to the firearm examiners, researchers, students pursuing study on forensic science as reference material. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=improvised%20pistol" title="improvised pistol">improvised pistol</a>, <a href="https://publications.waset.org/abstracts/search?q=stringent%20gun%20law" title=" stringent gun law"> stringent gun law</a>, <a href="https://publications.waset.org/abstracts/search?q=working%20mechanism" title=" working mechanism"> working mechanism</a>, <a href="https://publications.waset.org/abstracts/search?q=parameters" title=" parameters"> parameters</a>, <a href="https://publications.waset.org/abstracts/search?q=database" title=" database"> database</a> </p> <a href="https://publications.waset.org/abstracts/170615/characteristics-features-and-action-mechanism-of-some-country-made-pistols" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/170615.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">71</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">25</span> Optimation of Ethanol Extract of Gotu Kola and Majapahit Composition as Natural Antioxidant Source </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mustofa%20Ahda">Mustofa Ahda</a>, <a href="https://publications.waset.org/abstracts/search?q=Fiqri%20Rozi"> Fiqri Rozi</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Noor%20Habibah"> Gina Noor Habibah</a>, <a href="https://publications.waset.org/abstracts/search?q=Mas%20Ulfah%20Lestari"> Mas Ulfah Lestari</a>, <a href="https://publications.waset.org/abstracts/search?q=Tomy%20Hardianto"> Tomy Hardianto</a>, <a href="https://publications.waset.org/abstracts/search?q=Yuni%20Andriani"> Yuni Andriani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The development of natural antioxidants in the Centella asiatica and Majapahit is a great potential. This research has been optimizing the composition of ethanol extract of Centella asiatica and leaves Majapahit as an antioxidants source using measure the free radical scavenging activity of DPPH. The results of the research showed that both the ethanol extract of Centella asiatica and leaves Majapahit has a total content of phenol. It is shown with the ability to reduce reagent Folin Ciocalteu become blue colour. The composition optimization of extract Centella asiatica leaves Majapahit = 30:70 has free radical scavenging activity of DPPH most well compared ethanol extract of Centella asiatica and leaves Majapahit. IC50 values for the composition of ethanol extract of Centella asiatica : leaves Majapahit = 30:70 is 0,103 mg/mL. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title="antioxidant activity">antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=Centella%20asiatica" title=" Centella asiatica"> Centella asiatica</a>, <a href="https://publications.waset.org/abstracts/search?q=Cresentia%20cujete" title=" Cresentia cujete"> Cresentia cujete</a>, <a href="https://publications.waset.org/abstracts/search?q=composition%20extract" title=" composition extract"> composition extract</a> </p> <a href="https://publications.waset.org/abstracts/66718/optimation-of-ethanol-extract-of-gotu-kola-and-majapahit-composition-as-natural-antioxidant-source" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66718.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">329</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">24</span> Coordinated Community Response to Intimate Partner Violence on College Campuses</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Robert%20D.%20Hanser">Robert D. Hanser</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20M.%20Hanser"> Gina M. Hanser </a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper provides an overview of Coordinated Community Response Teams (CCRT) to Intimate Partner Violence (IPV). The CCRT, as a partnership and collaborative effort between multiple agencies is highlighted. This paper is a legal analysis that showcases new legislation and legal requirements in the United States for investigating, processing, and reporting to acts of victimization have transformed the role of the university’s CCRT on campus, making its mission all the more important, both internal and external to the campus. As a specific example, discussion of the CCRT in Northeast Louisiana at the University of Louisiana at Monroe is provided as an example of involvement in this initiative, where federal grant funding has allowed a micro version of the region’s CCRT to be implemented on that campus. Simultaneously, university personnel also work with external agencies throughout the community in intimate partner violence response. Amidst this, the result is a genuine partnership between practitioners and researchers who work together to provide public awareness, prevention, first-responder, and intervention services in a comprehensive manner throughout Northeast Louisiana. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=interperaonal%20violence" title="interperaonal violence">interperaonal violence</a>, <a href="https://publications.waset.org/abstracts/search?q=sexual%20assault" title=" sexual assault"> sexual assault</a>, <a href="https://publications.waset.org/abstracts/search?q=dating%20violence" title=" dating violence"> dating violence</a>, <a href="https://publications.waset.org/abstracts/search?q=campus%20violence" title=" campus violence"> campus violence</a> </p> <a href="https://publications.waset.org/abstracts/44569/coordinated-community-response-to-intimate-partner-violence-on-college-campuses" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/44569.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">309</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">23</span> Location-Domination on Join of Two Graphs and Their Complements</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Analen%20Malnegro">Analen Malnegro</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Malacas"> Gina Malacas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Dominating sets and related topics have been studied extensively in the past few decades. A dominating set of a graph G is a subset D of V such that every vertex not in D is adjacent to at least one member of D. The domination number γ(G) is the number of vertices in a smallest dominating set for G. Some problems involving detection devices can be modeled with graphs. Finding the minimum number of devices needed according to the type of devices and the necessity of locating the object gives rise to locating-dominating sets. A subset S of vertices of a graph G is called locating-dominating set, LD-set for short, if it is a dominating set and if every vertex v not in S is uniquely determined by the set of neighbors of v belonging to S. The location-domination number λ(G) is the minimum cardinality of an LD-set for G. The complement of a graph G is a graph Ḡ on same vertices such that two distinct vertices of Ḡ are adjacent if and only if they are not adjacent in G. An LD-set of a graph G is global if it is an LD-set of both G and its complement Ḡ. The global location-domination number λg(G) is defined as the minimum cardinality of a global LD-set of G. In this paper, global LD-sets on the join of two graphs are characterized. Global location-domination numbers of these graphs are also determined. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dominating%20set" title="dominating set">dominating set</a>, <a href="https://publications.waset.org/abstracts/search?q=global%20locating-dominating%20set" title=" global locating-dominating set"> global locating-dominating set</a>, <a href="https://publications.waset.org/abstracts/search?q=global%20location-domination%20number" title=" global location-domination number"> global location-domination number</a>, <a href="https://publications.waset.org/abstracts/search?q=locating-dominating%20set" title=" locating-dominating set"> locating-dominating set</a>, <a href="https://publications.waset.org/abstracts/search?q=location-domination%20number" title=" location-domination number"> location-domination number</a> </p> <a href="https://publications.waset.org/abstracts/92257/location-domination-on-join-of-two-graphs-and-their-complements" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/92257.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">22</span> Time Series Analysis of Air Pollution in Suceava County ( Nord- East of Romania)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lazurca%20Liliana%20Gina">Lazurca Liliana Gina</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Different time series analysis of yearly air pollution at Suceava County, Nord-East of Romania, has been performed in this study. The trends in the atmospheric concentrations of the main gaseous and particulate pollutants in urban, industrial and rural environments across Suceava County were estimated for the period of 2008-2014. The non-parametric Mann-Kendall test was used to determine the trends in the annual average concentrations of air pollutants (NO2, NO, NOx, SO2, CO, PM10, O3, C6H6). The slope was estimated using the non-parametric Sen’s method. Trend significance was assumed at the 5% significance level (p < 0.05) in the current study. During the 7 year period, trends in atmospheric concentrations may not have been monotonic, in some instances concentrations of species increased and subsequently decreased. The trend in Suceava County is to keep a low concentration of pollutants in ambient air respecting the limit values.All the results that we obtained show that Romania has taken a lot of regulatory measures to decrease the concentrations of air pollutants in the last decade, in Suceava County the air quality monitoring highlight for the most part of the analyzed pollutants decreasing trends. For the analyzed period we observed considerable improvements in background air in Suceava County. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pollutant" title="pollutant">pollutant</a>, <a href="https://publications.waset.org/abstracts/search?q=trend" title=" trend"> trend</a>, <a href="https://publications.waset.org/abstracts/search?q=air%20quality%20monitoring" title=" air quality monitoring"> air quality monitoring</a>, <a href="https://publications.waset.org/abstracts/search?q=Mann-Kendall" title=" Mann-Kendall "> Mann-Kendall </a> </p> <a href="https://publications.waset.org/abstracts/37687/time-series-analysis-of-air-pollution-in-suceava-county-nord-east-of-romania" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37687.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">365</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">21</span> Technological Measures to Reduce the Environmental Impact of Swimming Pools</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=F%C3%A1tima%20Farinha">Fátima Farinha</a>, <a href="https://publications.waset.org/abstracts/search?q=Miguel%20J.%20Oliveira"> Miguel J. Oliveira</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Matias"> Gina Matias</a>, <a href="https://publications.waset.org/abstracts/search?q=Armando%20Inverno"> Armando Inverno</a>, <a href="https://publications.waset.org/abstracts/search?q=J%C3%A2nio%20Monteiro"> Jânio Monteiro</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristiano%20Cabrita"> Cristiano Cabrita</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the last decades, the construction of swimming pools for recreational activities has grown exponentially in southern Europe. Swimming pools are used both for private use in villas and for collective use in hotels or condominiums. However, they have a high environmental impact, mainly in terms of water and energy consumption, being used for a short period of time, depending significantly on favorable atmospheric conditions. Contrary to what would be expected, not enough research has been conducted to reduce the negative impact of this equipment. In this context, this work proposes and analyses technological measures to reduce the environmental impacts of swimming pools, such as thermal insulation of the tank, water balance in order to detect leaks and optimize the backwash process, integration of renewable energy generation, and a smart control system that meets the requirements of the user. The work was developed within the scope of the Ecopool+++ project, which aims to create innovative heated pools with reduced thermal losses and integration of SMART energy plus water management systems. The project is in the final phase of its development, with very encouraging results. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=swimming%20pools" title="swimming pools">swimming pools</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=thermal%20losses" title=" thermal losses"> thermal losses</a>, <a href="https://publications.waset.org/abstracts/search?q=water%20management%20system" title=" water management system"> water management system</a> </p> <a href="https://publications.waset.org/abstracts/162446/technological-measures-to-reduce-the-environmental-impact-of-swimming-pools" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/162446.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">104</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> Exploring Management Strategies Used by Grade 1 Educators in the Classroom Working with Learners Presenting with ADHD Symptoms in the Western Cape</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Athena%20Pedro">Athena Pedro</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Stockingt"> Gina Stockingt</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study aimed to explore current management strategies used by Grade 1 educators working with learners presenting with Attention Deficit Hyperactivity Disorder (ADHD) symptoms in mainstream schools in the Western Cape. A sample of grade 1 educators were selected for the study. The sample comprised of twelve grades 1 educators from four local schools in the Western Cape. All twelve educators were individually interviewed and discussed the management strategies used in the classroom when working with learner presenting with ADHD symptoms. The data was analysed qualitatively with a focus in identifying, sorting and analyse meaning according to the subjective perception, understanding and behaviour of the grade 1 educators within their context. Furthermore, the social, cultural, political and physical environment of the participants were taken into consideration to explore and interpret the link between these elements. The findings were as follows: many educators felt that they did not receive enough training on Attention Deficit Hyperactivity Disorder, therefore lacking knowledge on how to apply management strategies to address this. Managing a diverse range of learners, lack of resources, lack of parental involvement, lack of assistance in the classroom, as well as distracted and disorganised children posed as challenges for educators working with learners presenting with Attention Deficit Hyperactivity Disorder symptoms. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ADHD" title="ADHD">ADHD</a>, <a href="https://publications.waset.org/abstracts/search?q=Grade%201%20educators" title=" Grade 1 educators"> Grade 1 educators</a>, <a href="https://publications.waset.org/abstracts/search?q=Learners" title=" Learners"> Learners</a>, <a href="https://publications.waset.org/abstracts/search?q=Management%20strategies" title=" Management strategies"> Management strategies</a> </p> <a href="https://publications.waset.org/abstracts/91557/exploring-management-strategies-used-by-grade-1-educators-in-the-classroom-working-with-learners-presenting-with-adhd-symptoms-in-the-western-cape" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91557.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">209</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> Antimicrobial Activity of Functionalized Alpaca Fabrics with Silver Nanoparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gina%20Zavaleta-Espejo">Gina Zavaleta-Espejo</a>, <a href="https://publications.waset.org/abstracts/search?q=Segundo%20R.%20J%C3%A1uregui-Rosas"> Segundo R. Jáuregui-Rosas</a>, <a href="https://publications.waset.org/abstracts/search?q=Fanny%20V.%20Samanamud-Moreno"> Fanny V. Samanamud-Moreno</a>, <a href="https://publications.waset.org/abstracts/search?q=Jos%C3%A9%20Salda%C3%B1a%20Jim%C3%A9nez"> José Saldaña Jiménez</a>, <a href="https://publications.waset.org/abstracts/search?q=Anibal%20Felix-Quintero"> Anibal Felix-Quintero</a>, <a href="https://publications.waset.org/abstracts/search?q=V%C3%ADctor%20Montero-Del%20Aguila"> Víctor Montero-Del Aguila</a>, <a href="https://publications.waset.org/abstracts/search?q=Elsi%20Mej%C3%ADa-Uriarte"> Elsi Mejía-Uriarte</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Vicugnapacos "alpaca" fabrics are considered special for their finesse, and the garments in the textile market are very luxurious. It has many special characteristics such as antiallergic, soft, hygroscopic, among others. In this sense, the research aimed to evaluate the antimicrobial activity of alpaca fabrics functionalized with silver nanoparticles on the bacteria Escherichia coli ATCC 25922 and Staphylococcus aureus ATCC 25923. For the functionalization of the fabrics, AgNO3 and different concentrations of trisodium citrate (TSC) 2, 6, and 10 mg. Tissue characterization was performed using Raman spectroscopy, Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The determination of the antimicrobial activity of the alpaca tissues was made by the Kirby-Bauer method with alpaca tissue discs functionalized with silver nanoparticles, an experimental design was made in completely randomized blocks with three treatments and a negative control with three repetitions. The results showed that inhibition halos were formed for both bacteria, therefore, the functionalized tissues have a high antimicrobial activity, whose mechanism of action is attributed to the free radicals (ROS) generated by the nanoparticles that cause oxidative damage to the bacteria. proteins and lipids of the bacterial cell wall. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antimicrobial" title="antimicrobial">antimicrobial</a>, <a href="https://publications.waset.org/abstracts/search?q=animal%20fibers" title=" animal fibers"> animal fibers</a>, <a href="https://publications.waset.org/abstracts/search?q=fabrics" title=" fabrics"> fabrics</a>, <a href="https://publications.waset.org/abstracts/search?q=functionalization" title=" functionalization"> functionalization</a>, <a href="https://publications.waset.org/abstracts/search?q=trisodium%20citrate" title=" trisodium citrate"> trisodium citrate</a> </p> <a href="https://publications.waset.org/abstracts/149105/antimicrobial-activity-of-functionalized-alpaca-fabrics-with-silver-nanoparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149105.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">136</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> Revolutionizing Higher Education: AI-Powered Gamification for Enhanced Learning</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gina%20L.%20Solano">Gina L. Solano</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This project endeavors to enhance learning experiences for undergraduate pre-service teachers and graduate K-12 educators by leveraging artificial intelligence (AI). Firstly, the initiative delves into integrating AI within undergraduate education courses, fostering traditional literacy skills essential for academic success and extending their applicability beyond the classroom. Education students will explore AI tools to design literacy-focused activities aligned with their curriculum. Secondly, the project investigates the utilization of AI to craft instructional materials employing gamification strategies (e.g., digital and classic games, badges, quests) to amplify student engagement and motivation in mastering course content. Lastly, it aims to create a professional repertoire that can be applied by pre-service and current teachers in P-12 classrooms, promoting seamless integration for those already in teaching positions. The project's impact extends to benefiting college students, including pre-service and graduate teachers, as they enhance literacy and digital skills through AI. It also benefits current P-12 educators who can integrate AI into their classrooms, fostering innovative teaching practices. Moreover, the project contributes to faculty development, allowing them to cultivate low-risk and engaging classroom environments, ultimately enriching the learning journey. The insights gained from this project can be shared within and beyond the discipline to advance the broader field of study. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=artificial%20intelligence" title="artificial intelligence">artificial intelligence</a>, <a href="https://publications.waset.org/abstracts/search?q=gamification" title=" gamification"> gamification</a>, <a href="https://publications.waset.org/abstracts/search?q=learning%20experiences" title=" learning experiences"> learning experiences</a>, <a href="https://publications.waset.org/abstracts/search?q=literacy%20skills" title=" literacy skills"> literacy skills</a>, <a href="https://publications.waset.org/abstracts/search?q=engagement" title=" engagement"> engagement</a> </p> <a href="https://publications.waset.org/abstracts/183497/revolutionizing-higher-education-ai-powered-gamification-for-enhanced-learning" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183497.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">62</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> Retrospective Insight on the Changing Status of the Romanian Language Spoken in the Republic of Moldova</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gina%20Aurora%20Necula">Gina Aurora Necula</a> </p> <p class="card-text"><strong>Abstract:</strong></p> From its transformation into a taboo and its hiding under the so-called “Moldovan language” or under the euphemistic expression “state language” to its regained status recognition as an official language, the Romanian language spoken in the Republic of Moldova has undergone impressive reforms in the last 60 years. Meant to erase the awareness of citizens’ ethnic identity and turn a majority language into a minority one, all the laws and regulations issued on the field succeeded into setting numerous barriers for speakers of Romanian. Either manifested as social constraints or materialized into assumed rejection of mother tongue usage, all these laws have demonstrated their usefulness and major impact on the Romanian-speaking population. This article is the result of our research carried out over 10 years with the support of students, and Moldovan citizens, from the master's degree program "Romanian language - identity and cultural awareness." We present here a retrospective insight of the reforms, laws, and regulations that contributed to the shifted status of the Romanian language from the official language, seen as the language of common use both in the public and private spheres, in the minority language that surrendered its privileged place to the Russian language, firstly in the public sphere, and then, slowly but surely, in the private sphere. Our main goal here is to identify and make speakers understand what the barriers to learning Romanian language are nowadays when the social pressure on using Russian no longer exists. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=linguistic%20barriers" title="linguistic barriers">linguistic barriers</a>, <a href="https://publications.waset.org/abstracts/search?q=lingua%20franca" title=" lingua franca"> lingua franca</a>, <a href="https://publications.waset.org/abstracts/search?q=private%20sphere" title=" private sphere"> private sphere</a>, <a href="https://publications.waset.org/abstracts/search?q=public%20sphere" title=" public sphere"> public sphere</a>, <a href="https://publications.waset.org/abstracts/search?q=reformation" title=" reformation"> reformation</a> </p> <a href="https://publications.waset.org/abstracts/151966/retrospective-insight-on-the-changing-status-of-the-romanian-language-spoken-in-the-republic-of-moldova" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151966.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">115</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> The Anti-Obesity Effects of the Aqueous and Ethanolic Leaf Extracts of Blumea balsamifera on Diet-Induced Obese Sprague-Dawley Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mae%20Genevieve%20G.%20Cheung">Mae Genevieve G. Cheung</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20G.%20Cuevas"> Michael G. Cuevas</a>, <a href="https://publications.waset.org/abstracts/search?q=Lovely%20Fe%20L.%20Cuison"> Lovely Fe L. Cuison</a>, <a href="https://publications.waset.org/abstracts/search?q=Elijin%20P.%20Dai"> Elijin P. Dai</a>, <a href="https://publications.waset.org/abstracts/search?q=Katrina%20Marie%20S.%20Duron"> Katrina Marie S. Duron</a>, <a href="https://publications.waset.org/abstracts/search?q=Azalea%20Damaris%20E.%20Encarnacion"> Azalea Damaris E. Encarnacion</a>, <a href="https://publications.waset.org/abstracts/search?q=May%20T.%20Magtoto"> May T. Magtoto</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20C.%20Castro"> Gina C. Castro</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present study aims to evaluate the effectiveness of aqueous and ethanolic leaf extracts of Blumea balsamifera in reducing obesity on diet-induced obese Sprague-Dawley rats. Aqueous and ethanolic leaf extracts were obtained by maceration and percolation, respectively, of air-dried, grinded leaves. The test animals were given a high fat diet (HFD) for 21 days, except for one negative control group fed with a standard diet (SD). The Blumea balsamifera extracts were given at doses of 300 mg/Kg and 600 mg/Kg for BBAE and BBEE groups, and the positive control group, Orlistat, was given at 21.6 mg/Kg dose. After 24 days of treatment, the statistical difference of parameters such as Lee’s index and lipid profile of each group before and after the treatment period were determined separately using Tukey’s test of two-way Analysis of Variance (ANOVA). The statistical results showed that the600mg/kg dose of BBAE and BBEE had greatly lowered the Lee’s index among the other doses while the 300 mg/Kg dose BBEE, 600 mg/Kg BBAE, and 300 mg/kg BBAE lowered the total cholesterol level, LDL level, and VLDL and total triglyceride level respectively. The extracts, however, lowered the HDL level which was also exhibited by the standard drug, Orlistat. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adipocytes" title="adipocytes">adipocytes</a>, <a href="https://publications.waset.org/abstracts/search?q=adipogenesis" title=" adipogenesis"> adipogenesis</a>, <a href="https://publications.waset.org/abstracts/search?q=Blumea%20balsamifera" title=" Blumea balsamifera"> Blumea balsamifera</a>, <a href="https://publications.waset.org/abstracts/search?q=Lee%E2%80%99s%20index" title=" Lee’s index"> Lee’s index</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity"> obesity</a>, <a href="https://publications.waset.org/abstracts/search?q=Sambong" title=" Sambong"> Sambong</a> </p> <a href="https://publications.waset.org/abstracts/46727/the-anti-obesity-effects-of-the-aqueous-and-ethanolic-leaf-extracts-of-blumea-balsamifera-on-diet-induced-obese-sprague-dawley-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46727.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">376</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Sustainable Affordable Housing Development in Indonesia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gina%20Cynthia%20Raphita%20Hasibuan">Gina Cynthia Raphita Hasibuan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The housing sector in Indonesia is in critical condition where majority of low-income citizens live in substandard dwellings, and the number housing backlog is increasing every year. The housing problem becomes more urgent when the term 'sustainability' is considered, and sustainable affordable housing is yet to gain its successful implementation. Global urbanization develops fastest in developing countries like Indonesia where informal settlements are rapidly escalating, hence, making sustainable affordable housing strategies very critical in this context. The problem in developing countries like Indonesia lies on the institutional capacity of newly-established local governments having greater power to determine a development policy but apparently still lacking institutional capability and coordination with the central government and collaborative governance are still not established yet. The concept of upgrading informal settlements are seen changed over time and inconsistent. Despite much research on theme such as sustainable housing concept within Indonesian context, there has been a dearth of research examining the role of collaborative governance, as the current approach still shows fragmented approach between the stakeholders and the lack of community participation as the end user, and thus this research attempts to fill the gap on the aforementioned problems. By using case study with multi-methods conducted in Jakarta, this research has an overall aim to critically assess the role of collaborative governance in addressing sustainable affordable housing in Indonesia and to understand informal settlements and interventions in Indonesia rather than imposing a framework from western perspectives. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=affordable%20housing" title="affordable housing">affordable housing</a>, <a href="https://publications.waset.org/abstracts/search?q=collaborative%20governance" title=" collaborative governance"> collaborative governance</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a>, <a href="https://publications.waset.org/abstracts/search?q=urban%20planning" title=" urban planning"> urban planning</a> </p> <a href="https://publications.waset.org/abstracts/73813/sustainable-affordable-housing-development-in-indonesia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/73813.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">410</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Water Treatment Using Eichhornia crassipes and Avifauna Control in The "La Mansión" Pond</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milda%20A.%20Cruz-Huaranga">Milda A. Cruz-Huaranga</a>, <a href="https://publications.waset.org/abstracts/search?q=Natal%C3%AD%20Carbo-Bustinza"> Natalí Carbo-Bustinza</a>, <a href="https://publications.waset.org/abstracts/search?q=Javier%20Linkolk%20L%C3%B3pez-Gonzales"> Javier Linkolk López-Gonzales</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Depaz"> K. Depaz</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20M.%20Tito%20T."> Gina M. Tito T.</a>, <a href="https://publications.waset.org/abstracts/search?q=Soledad%20Torres-Calder%C3%B3n"> Soledad Torres-Calderón</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The objective of this study was to improve water quality in the “La Mansión” pond in order to irrigate green spaces on the Peruvian Union University campus (Lima, Peru) using the aquatic species Eichhornia Crassipes. Furthermore, tree trimming and cleaning activities were performed that reduced water pollution caused by organic deposits and feathers from wild birds. The impaired waterbody is located on the campus of the Peruvian Union University, 580 meters above sea level, with a volume of 6,405.336 m3, an area of 3,050.16 m2, 256.81 m perimeter, and 0.12 m3/s input flow. Seven 1.8 m2 floating systems were implemented, with 12 common water hyacinth plants in each system. Before implementing this system, a water quality analysis was performed to analyse the physical-chemical, microbiological, and organoleptic parameters. The pre-analysis revealed the pond’s critical condition, with electrical conductivity: 556 mg/l; phosphate: < 0.5; pH: 7.06; total solids: 412 mg/l; arsenic: <0.01; lead: 0.115; BOD5: 14; COD: 16.94; dissolved oxygen: 13; total coliforms: 24000 MCL/100 ml; and thermo-tolerant coliforms: 11000 MCL/100 ml. After implementing the system, the following results were obtained: EC: 495 mg/l; DO:9.2 mg/l; TS: 235 mg/l; BOD5: 7.7; COD: 8.47; Pb: 0.001 mg/l; TC: 460 MCL/100 ml; FC: 240 MCL/100 ml. Thus, we confirmed that the system is 78.79% efficient regarding the Peruvian ECA (Environmental Quality Standards) established for water according to DS #015-2015-MINAM. Therefore, the water is suitable for plant irrigation. Finally, we concluded that treating wastewater with the species Eichhornia Crassipes is efficient since an improvement was achieved in the impaired waterbody. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eichhornia%20crassipes" title="Eichhornia crassipes">Eichhornia crassipes</a>, <a href="https://publications.waset.org/abstracts/search?q=plantlets" title=" plantlets"> plantlets</a>, <a href="https://publications.waset.org/abstracts/search?q=cleaning" title=" cleaning"> cleaning</a>, <a href="https://publications.waset.org/abstracts/search?q=impaired%20waterbody" title=" impaired waterbody"> impaired waterbody</a>, <a href="https://publications.waset.org/abstracts/search?q=pond" title=" pond"> pond</a> </p> <a href="https://publications.waset.org/abstracts/156789/water-treatment-using-eichhornia-crassipes-and-avifauna-control-in-the-la-mansion-pond" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156789.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">140</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> A Theoretical Framework: The Influence of Luxury Companies' Corporate Social Activities on Consumer Purchase Intention</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kveta%20Olsanova">Kveta Olsanova</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Cook"> Gina Cook</a>, <a href="https://publications.waset.org/abstracts/search?q=Marija%20Zlatic"> Marija Zlatic</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper discusses the theoretical framework suggesting the dependencies between luxury brands’ CSR (Corporate Social Responsibility) variables and the purchase intention of luxury shoppers. The framework is based on a literature review and in-depth individual interviews with a sample of luxury users and buyers. The measures of the model are based on existing research and the authors' qualitative research results. The model suggests that purchase intention in the luxury segment is dependent on the luxury values (symbolic, experiential, functional and social), individual sustainable dimension (composed of societal, environmental and economic variables) and awareness of the brand’s CSR, the last two relationships being potentially moderated by certain conditions such as demographics and general attitudes towards CSR and sustainability. The model’s output is in the formulation of several hypotheses, to be tested in an upcoming quantitative study. The qualitative phase indicated that the perceived symbolic, functional and experiential value dimensions of luxury brands were stronger drivers of purchase intention compared to the sustainable dimension. The contribution of the research consists of highlighting CSR’s impact on customer purchase intent as a potential implication for luxury brand management due to two aspects: (i) consumer awareness of the existing CSR activities of luxury brands is low, and this might be challenged by the demands of Gen Z entrants into the lux industry as they are known for their positive approach to CSR; (ii) the UN’s SDGs will bring CSR to the attention of all industries, including currently 'CSR silent' segments represented by luxury. Our research should contribute to incorporation of strategic CSR into the policies and strategies of the luxury segment by providing evidence that luxury customers do care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CSR" title="CSR">CSR</a>, <a href="https://publications.waset.org/abstracts/search?q=luxury%20shoppers" title=" luxury shoppers"> luxury shoppers</a>, <a href="https://publications.waset.org/abstracts/search?q=purchase%20intention" title=" purchase intention"> purchase intention</a>, <a href="https://publications.waset.org/abstracts/search?q=sustainability" title=" sustainability"> sustainability</a> </p> <a href="https://publications.waset.org/abstracts/101665/a-theoretical-framework-the-influence-of-luxury-companies-corporate-social-activities-on-consumer-purchase-intention" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/101665.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">148</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> RNAseq Reveals Hypervirulence-Specific Host Responses to M. tuberculosis Infection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gina%20Leisching">Gina Leisching</a>, <a href="https://publications.waset.org/abstracts/search?q=Ray-Dean%20Pietersen"> Ray-Dean Pietersen</a>, <a href="https://publications.waset.org/abstracts/search?q=Carel%20Van%20Heerden"> Carel Van Heerden</a>, <a href="https://publications.waset.org/abstracts/search?q=Paul%20Van%20Helden"> Paul Van Helden</a>, <a href="https://publications.waset.org/abstracts/search?q=Ian%20Wiid"> Ian Wiid</a>, <a href="https://publications.waset.org/abstracts/search?q=Bienyameen%20Baker"> Bienyameen Baker</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The distinguishing factors that characterize the host response to infection with virulent Mycobacterium tuberculosis (M.tb) are largely confounding. We present an infection study with two genetically closely related M.tb strains that have vastly different pathogenic characteristics. The early host response to infection with these detergent-free cultured strains was analyzed through RNAseq in an attempt to provide information on the subtleties which may ultimately contribute to the virulent phenotype. Murine bone marrow-derived macrophages (BMDMs) were infected with either a hyper- (R5527) or hypovirulent (R1507) Beijing M. tuberculosis clinical isolate. RNAseq revealed 69 differentially expressed host genes in BMDMs during comparison of these two transcriptomes. Pathway analysis revealed activation of the stress-induced and growth inhibitory Gadd45 signaling pathway in hypervirulent infected BMDMs. Upstream regulators of interferon activation such as and IRF3 and IRF7 were predicted to be upregulated in hypovirulent-infected BMDMs. Additional analysis of the host immune response through ELISA and qPCR included the use of human THP-1 macrophages where a robust proinflammatory response was observed after infection with the hypervirulent strain. RNAseq revealed two early-response genes (IER3 and SAA3) and two host-defence genes (OASL1 and SLPI) that were significantly upregulated by the hypervirulent strain. The role of these genes under M.tb infection conditions are largely unknown but here we provide validation of their presence with use of qPCR and Western blot. Further analysis into their biological role under infection with virulent M.tb is required. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=host-response" title="host-response">host-response</a>, <a href="https://publications.waset.org/abstracts/search?q=Mycobacterium%20tuberculosis" title=" Mycobacterium tuberculosis"> Mycobacterium tuberculosis</a>, <a href="https://publications.waset.org/abstracts/search?q=RNAseq" title=" RNAseq"> RNAseq</a>, <a href="https://publications.waset.org/abstracts/search?q=virulence" title=" virulence"> virulence</a> </p> <a href="https://publications.waset.org/abstracts/59133/rnaseq-reveals-hypervirulence-specific-host-responses-to-m-tuberculosis-infection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59133.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">210</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> University of Sciences and Technology of Oran Mohamed Boudiaf (USTO-MB)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Patricia%20Mikchaela%20D.%20L.%20Feliciano">Patricia Mikchaela D. L. Feliciano</a>, <a href="https://publications.waset.org/abstracts/search?q=Ciela%20Kadeshka%20A.%20Fuentes"> Ciela Kadeshka A. Fuentes</a>, <a href="https://publications.waset.org/abstracts/search?q=Bea%20Trixia%20B.%20Gales"> Bea Trixia B. Gales</a>, <a href="https://publications.waset.org/abstracts/search?q=Ethel%20Princess%20A.%20Gepulango"> Ethel Princess A. Gepulango</a>, <a href="https://publications.waset.org/abstracts/search?q=Martin%20R.%20Hernandez"> Martin R. Hernandez</a>, <a href="https://publications.waset.org/abstracts/search?q=Elina%20Andrea%20S.%20Lantion"> Elina Andrea S. Lantion</a>, <a href="https://publications.waset.org/abstracts/search?q=Jhoe%20Cynder%20P.%20Legaspi"> Jhoe Cynder P. Legaspi</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20F.%20Quilala"> Peter F. Quilala</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20C.%20Castro"> Gina C. Castro</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Propolis is a resin-like material used by bees to fill large gap holes in the beehive. It has been found to possess anti-inflammatory property, which stimulates hair growth in rats by inducing hair keratinocytes proliferation, causing water retention and preventing damage caused by heat, ultraviolet rays, and other microorganisms without abnormalities in hair follicles. The present study aimed to formulate 10% and 30% Propolis Hair Cream for use in enhancing hair properties. Raw propolis sample was tested for heavy metals using Atomic Absorption Spectroscopy; zinc and chromium were found to be present. Likewise, propolis was extracted in a percolator using 70% ethanol and concentrated under vacuum using a rotary evaporator. The propolis extract was analyzed for total flavonoid content. Compatibility of the propolis extract with excipients was evaluated using Differential Scanning Calorimetry (DSC). No significant changes in organoleptic properties, pH and viscosity of the formulated creams were noted after four weeks of storage at 2-8°C, 30°C, and 40°C. The formulated creams were found to be non-irritating based on the Modified Draize Rabbit Test. In vivo efficacy was evaluated based on thickness and tensile strength of hair grown on previously shaved rat skin. Results show that the formulated 30% propolis-based cream had greater hair enhancing properties than the 10% propolis cream, which had a comparable effect with minoxidil. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=atomic%20absorption%20spectroscopy" title="atomic absorption spectroscopy">atomic absorption spectroscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=differential%20scanning%20calorimetry%20%28DSC%29" title=" differential scanning calorimetry (DSC)"> differential scanning calorimetry (DSC)</a>, <a href="https://publications.waset.org/abstracts/search?q=modified%20draize%20rabbit%20test" title=" modified draize rabbit test"> modified draize rabbit test</a>, <a href="https://publications.waset.org/abstracts/search?q=propolis" title=" propolis"> propolis</a> </p> <a href="https://publications.waset.org/abstracts/46362/university-of-sciences-and-technology-of-oran-mohamed-boudiaf-usto-mb" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/46362.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">343</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Spatio-Temporal Analysis of Rabies Incidence in Herbivores of Economic Interest in Brazil</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Francisco%20Miroslav%20Ulloa-Stanojlovic">Francisco Miroslav Ulloa-Stanojlovic</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Polo"> Gina Polo</a>, <a href="https://publications.waset.org/abstracts/search?q=Ricardo%20Augusto%20Dias"> Ricardo Augusto Dias</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In Brazil, there is a high incidence of rabies in herbivores of economic interest (HEI) transmitted by the common vampire bat Desmodus rotundus, the presence of human rabies cases and the huge economic losses in the world's largest cattle industry, it is important to assist the National Program for Control of Rabies in herbivores in Brazil, that aims to reduce the incidence of rabies in HEI populations, mainly through epidemiological surveillance, vaccination of herbivores and control of vampire-bat roosts. Material and Methods: A spatiotemporal retrospective Kulldorff's spatial scan statistic based on a Poisson model and Monte Carlo simulation and an Anselin's Local Moran's I statistic were used to uncover spatial clustering of HEI rabies from 2000 – 2014. Results: Were identify three important clusters with significant year-to-year variation (Figure 1). In 2000, was identified one area of clustering in the North region, specifically in the State of Tocantins. Between the year 2000 and 2004, a cluster centered in the Midwest and Southeast region including the States of Goiás, Minas Gerais, Rio de Janeiro, Espirito Santo and São Paulo was prominent. And finally between 2000 and 2005 was found an important cluster in the North, Midwest and South region. Conclusions: The HEI rabies is endemic in the country, in addition, appears to be significant differences among the States according to their surveillance services, that may be difficulting the control of the disease, also other factors could be influencing in the maintenance of this problem like the lack of information of vampire-bat roosts identification, and limited human resources for realization of field monitoring. A review of the program control by the authorities it’s necessary. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Brazil" title="Brazil">Brazil</a>, <a href="https://publications.waset.org/abstracts/search?q=Desmodus%20rotundus" title=" Desmodus rotundus"> Desmodus rotundus</a>, <a href="https://publications.waset.org/abstracts/search?q=herbivores" title=" herbivores"> herbivores</a>, <a href="https://publications.waset.org/abstracts/search?q=rabies" title=" rabies"> rabies</a> </p> <a href="https://publications.waset.org/abstracts/48219/spatio-temporal-analysis-of-rabies-incidence-in-herbivores-of-economic-interest-in-brazil" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48219.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">417</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Design and Synthesis of Some Pyrimidine Derivatives as Bruton’s Tyrosine Kinase Inhibitors for Hematologic Malignancies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ibrahim%20M.%20Labouta">Ibrahim M. Labouta</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20N.%20Tageldin"> Gina N. Tageldin</a>, <a href="https://publications.waset.org/abstracts/search?q=Salwa%20M.%20Fahmy"> Salwa M. Fahmy</a>, <a href="https://publications.waset.org/abstracts/search?q=Hayam%20M.%20Ashour"> Hayam M. Ashour</a>, <a href="https://publications.waset.org/abstracts/search?q=Mounir%20A.%20Khalil"> Mounir A. Khalil</a>, <a href="https://publications.waset.org/abstracts/search?q=Tamer%20M.%20Ibrahim"> Tamer M. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Nefertiti%20A.%20El-Nikhely"> Nefertiti A. El-Nikhely</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bruton’s tyrosine kinase (BTK) is a critical effector molecule in B cell antigen receptor (BCR) signaling transduction. It regulates B cell proliferation, development and survival. Since BTK is widely expressed in many B cell leukaemias and lymphomas, targeting BTK by small molecules inhibitors became an attractive idea as new treatment modalities for B cell mediated hematologic malignancies. Ibrutinib is the 1st generation BTK inhibitor, approved by FDA for treatment of relapsed mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL). It binds irreversibly to the unique cysteine (Cys481) within the ATP-binding pocket of BTK. Besides ibrutinib, many irreversible covalent BTK inhibitors comprising pyrimidine nucleus such as spebrutinib (phase IIb) showed high selectivity and potency when compared to it. In this study, the designed compounds were based on 5-cyano-2-methylsulfanyl pyrimidine core and decorated with electrophilic warheads which are essential for the optimal activity for targeted covalent inhibition (TCI). However, modifications at pyrimidine C4 or C6 were made by introduction of substituted amines which are provided to behave differently. The synthesized derivatives were evaluated for their anticancer activity in leukemia cell lines (e.g. THP-1). Results showed that, some derivatives exhibited antiproliferative activity with IC50 ranged from 5-50 μM, The in vitro enzymatic inhibitory assay for these compounds against BTK is still under investigation. Nevertheless, we could conclude from the initial biological screening that, the synthesized 4 or 6-subsitituted aminopyrimidines represent promising and novel antileukemic agents. Meanwhile, further studies are still needed to attribute this activity through targeting BTK enzyme and inhibition of BCR signaling pathway. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=BTK%20inhibitors" title="BTK inhibitors">BTK inhibitors</a>, <a href="https://publications.waset.org/abstracts/search?q=hematologic%20malignancies" title=" hematologic malignancies"> hematologic malignancies</a>, <a href="https://publications.waset.org/abstracts/search?q=structure%20based%20drug%20design%20%28SBDD%29" title=" structure based drug design (SBDD)"> structure based drug design (SBDD)</a>, <a href="https://publications.waset.org/abstracts/search?q=targeted%20covalent%20inhibitors%20%28TCI%29" title=" targeted covalent inhibitors (TCI)"> targeted covalent inhibitors (TCI)</a> </p> <a href="https://publications.waset.org/abstracts/120895/design-and-synthesis-of-some-pyrimidine-derivatives-as-brutons-tyrosine-kinase-inhibitors-for-hematologic-malignancies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/120895.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">148</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Effect of Gamma Radiation, Age of Paddy, Rice Variety and Packaging Materials on the Surface Free Fatty Acid Content of Brown Rice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zenaida%20M.%20De%20Guzman">Zenaida M. De Guzman</a>, <a href="https://publications.waset.org/abstracts/search?q=Davison%20T.%20Baldos"> Davison T. Baldos</a>, <a href="https://publications.waset.org/abstracts/search?q=Gilberto%20T.%20Diano"> Gilberto T. Diano</a>, <a href="https://publications.waset.org/abstracts/search?q=Jeff%20Darren%20G.%20Valdez"> Jeff Darren G. Valdez</a>, <a href="https://publications.waset.org/abstracts/search?q=Levelyn%20Mitos%20Tolentino"> Levelyn Mitos Tolentino</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20B.%20Abrera"> Gina B. Abrera</a>, <a href="https://publications.waset.org/abstracts/search?q=Ma.%20Lucia%20Cobar"> Ma. Lucia Cobar</a>, <a href="https://publications.waset.org/abstracts/search?q=Cristina%20Gragasin"> Cristina Gragasin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> One of the factors affecting the quality of brown rice is the free fatty acid produced from surface lipids. It is the purpose of the study to determine the effect of gamma radiation, packaging materials and age and variety of paddy on the surface free fatty acid content using two different brown rice variety, namely, RC-160 and SL-7, packed in two different packaging materials, namely, regular polyethylene bag and Super bag irradiated at 0.5 and 1.0 kGy. Brown rice was produced from 2-week old (Lot 1) and two months old paddy (Lot 2) and irradiated at the Co-60 Multipurpose Irradiation Facility, PNRI. The surface Free Fatty Acid (FFA) content was obtained following the AOCS Official Method (1982) with some modifications. The experiment was laid out using Split-Plot Randomized Control Block Design. Analysis of variance (ANOVA) showed that the effects of variety, age of paddy and interactions of both were both significant. The surface FFA of SL-7 variety was found to be significantly higher than the RC-160 variety for all radiation doses. Likewise, Lot 2 was observed to have higher surface FFA than Lot 1 regardless of packaging material and radiation dose. It was observed that the surface FFA of both varieties packed in both packaging materials increased significantly up to the 2nd or 3rd month of storage and remains the same until the 5th month. On the other hand, radiation dose did not significantly affect the surface free fatty acid content for all storage/sampling time while the packaging material significantly interacts with the type of variety and radiation dose. Gamma radiation was proven to have no significant effect on the surface free fatty acid at 0.5 and 1.0 kGy and further analyses are needed to determine the action of gamma radiation to the activity of enzyme (lipase-induced and microbial) responsible for the production of other lipolytic products and the effect of gamma radiation on the integrity of the packaging materials. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=brown%20rice" title="brown rice">brown rice</a>, <a href="https://publications.waset.org/abstracts/search?q=free%20fatty%20acid" title=" free fatty acid"> free fatty acid</a>, <a href="https://publications.waset.org/abstracts/search?q=gamma%20radiation" title=" gamma radiation"> gamma radiation</a>, <a href="https://publications.waset.org/abstracts/search?q=polyethylene%20bag" title=" polyethylene bag "> polyethylene bag </a> </p> <a href="https://publications.waset.org/abstracts/58253/effect-of-gamma-radiation-age-of-paddy-rice-variety-and-packaging-materials-on-the-surface-free-fatty-acid-content-of-brown-rice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58253.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">389</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Management of Severe Asthma with Omalizumab in United Arab Emirates</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shanza%20Akram">Shanza Akram</a>, <a href="https://publications.waset.org/abstracts/search?q=Samir%20Salah"> Samir Salah</a>, <a href="https://publications.waset.org/abstracts/search?q=Imran%20Saleem"> Imran Saleem</a>, <a href="https://publications.waset.org/abstracts/search?q=Jassim%20Abdou"> Jassim Abdou</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashraf%20Al%20Zaabi"> Ashraf Al Zaabi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Estimated prevalence of asthma in UAE is around 10% (900,000 people). Patients with persistent symptoms despite using high dose ICS plus a second controller +/- Oral steroids are considered to have severe asthma. Omalizumab (Xolair) is an anti-IgE monoclonal antibody approved as add-on therapy for severe allergic asthma. The objective of our study was to obtain baseline characteristics of our local cohort, to determine the efficacy of omalizumab based on clinical outcomes pre and post 52 weeks of treatment and to assess safety and tolerability. Medical records of patients receiving omalizumab therapy for asthma at Zayed Military Hospital, Abu Dhabi were retrospectively reviewed. Patients fulfilling the criteria for severe allergic asthma as per GINA guidelines were included. Asthma control over 12 months pre and post omalizumab were analyzed by taking into account the number of exacerbations, hospitalizations, maintenance of medication dosages, the need for reliever therapy and PFT’s. 21 patients (5 females) with mean age 41 years were included. The mean duration of therapy was 22 months. 19 (91%) patients had Allergic Rhinitis/Sinusitis. Mean serum total IgE level was 648 IU/ml (65-1859). 11 (52%) patients were on oral maintenance steroids pre-treatment. 7 patients managed to stop steroids on treatment while 4 were able to decrease the dosage. Mean exacerbation rate decreased from 5 per year pre-treatment to 1.36 while on treatment. The number of hospitalizations decreased from a mean of 2 per year to 0.9 per year. Reliever inhaler usage decreased from mean of 40 to 15 puffs per week.2 patients discontinued therapy, 1 due to lack of benefit (2 doses) and 2nd due to severe persistent side effects. Patient compliance was poor in some cases. Treatment with omalizumab reduced the number of exacerbations, hospitalizations, maintenance and reliever medications, and is generally well tolerated. Our results show that there is room for improved documentation in terms of symptom recording and use of rescue medication at our institution. There is also need for better patient education and counseling in order to improve compliance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=asthma" title="asthma">asthma</a>, <a href="https://publications.waset.org/abstracts/search?q=exacerbations" title=" exacerbations"> exacerbations</a>, <a href="https://publications.waset.org/abstracts/search?q=omalizumab" title=" omalizumab"> omalizumab</a>, <a href="https://publications.waset.org/abstracts/search?q=IgE" title=" IgE"> IgE</a> </p> <a href="https://publications.waset.org/abstracts/35274/management-of-severe-asthma-with-omalizumab-in-united-arab-emirates" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/35274.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">371</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> T Cell Immunity Profile in Pediatric Obesity and Asthma </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mustafa%20M.%20Donma">Mustafa M. Donma</a>, <a href="https://publications.waset.org/abstracts/search?q=Erkut%20Karasu"> Erkut Karasu</a>, <a href="https://publications.waset.org/abstracts/search?q=Burcu%20Ozdilek"> Burcu Ozdilek</a>, <a href="https://publications.waset.org/abstracts/search?q=Burhan%20Turgut"> Burhan Turgut</a>, <a href="https://publications.waset.org/abstracts/search?q=Birol%20Topcu"> Birol Topcu</a>, <a href="https://publications.waset.org/abstracts/search?q=Burcin%20Nalbantoglu"> Burcin Nalbantoglu</a>, <a href="https://publications.waset.org/abstracts/search?q=Orkide%20Donma"> Orkide Donma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The mechanisms underlying the association between obesity and asthma may be related to a decreased immunological tolerance induced by a defective function of regulatory T cells (Tregs). The aim of this study is to establish the potential link between these diseases and CD4+, CD25+ FoxP3+ Tregs as well as T helper cells (Ths) in children. This is a prospective case control study. Obese (n:40), asthmatic (n:40), asthmatic obese (n:40), and healthy children (n:40), who don't have any acute or chronic diseases, were included in this study. Obese children were evaluated according to WHO criteria. Asthmatic patients were chosen based on GINA criteria. Parents were asked to fill up the questionnaire. Informed consent forms were taken. Blood samples were marked with CD4+, CD25+ and FoxP3+ in order to determine Tregs and Ths by flow cytometric method. Statistical analyses were performed. p≤0.05 was chosen as meaningful threshold. Tregs exhibiting anti-inflammatory nature were significantly lower in obese (0,16%; p≤0,001), asthmatic (0,25%; p≤0,01) and asthmatic obese (0,29%; p≤0,05) groups than the control group (0,38%). Ths were counted higher in asthma group than the control (p≤0,01) and obese (p≤0,001)) groups. T cell immunity plays important roles in obesity and asthma pathogeneses. Decreased numbers of Tregs found in obese, asthmatic and asthmatic obese children may help to elucidate some questions in pathophysiology of these diseases. For HOMA-IR levels, any significant difference was not noted between control and obese groups, but statistically higher values were found for obese asthmatics. The values obtained in all groups were found to be below the critical cut off points. This finding has made the statistically significant difference observed between Tregs of obese, asthmatic, obese asthmatic, and control groups much more valuable. These findings will be useful in diagnosis and treatment of these disorders and future studies are needed. The production and propagation of Tregs may be promising in alternative asthma and obesity treatments. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=asthma" title="asthma">asthma</a>, <a href="https://publications.waset.org/abstracts/search?q=flow%20cytometry" title=" flow cytometry"> flow cytometry</a>, <a href="https://publications.waset.org/abstracts/search?q=pediatric%20obesity" title=" pediatric obesity"> pediatric obesity</a>, <a href="https://publications.waset.org/abstracts/search?q=T%20cells" title=" T cells "> T cells </a> </p> <a href="https://publications.waset.org/abstracts/30529/t-cell-immunity-profile-in-pediatric-obesity-and-asthma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30529.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">346</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Omalizumab Therapy Experience for Asthma, at Zayed Military Hospital (ZMH) in United Arab Emirates </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shanza%20Akram">Shanza Akram</a>, <a href="https://publications.waset.org/abstracts/search?q=Samir%20Salah"> Samir Salah</a>, <a href="https://publications.waset.org/abstracts/search?q=Imran%20Saleem"> Imran Saleem</a>, <a href="https://publications.waset.org/abstracts/search?q=Ashraf%20Alzaabi"> Ashraf Alzaabi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jassim%20Abdou"> Jassim Abdou </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: 300 million people worldwide are affected by asthma .In UAE, prevalence is around 10% (900,000 people).Patients with persistent symptoms despite using high dose ICS plus a second controller +/- OCS are considered to have severe asthma. Omalizumab (Xolaire) an IgE monoclonal antibody is approved as add on therapy for severe allergic asthma. Objective: To determine the efficacy of omalizumab based on clinical outcomes in our cohort of patient pre and post 52 weeks of treatment to assess safety and tolerability of treatment. Methods: Medical records of patients receiving omalizumab therapy for asthma at ZMH ,Abu Dhabi were retrospectively analyzed.Patients fulfilling the criteria of severe allergic asthma as per GINA guidelines were included. Asthma control over 12 months prior to and 12 months after commencement of omalizumab therapy was analysed by taking into account the number of exacerbations and hospitalizations in addition to maintenance of medication dosages, need for rescue reliever therapy and pulmonary function testing. Results: Total cohort of 21 patient (5 females), average age 41 years and av length of therapy 22 months were included. Seven patients (total 11/52%) managed to stop steroids on treatment while four were able to decrease the dosage. Mean exacerbation rate decreased from five/ year pre treatment to 1.36 while on treatment. Number of hospitalizations decreased from mean of two per year to 0.9 per year. Rescue reliever inhaler usage decreased from mean of 40 puffs to 15 puffs per week. 2 patients discontinued therapy, 1 due to lack of benefit (2 doses) and 2nd due to severe persistent side effects including local irritation, severe limb and joint pains after 6 months. Conclusion: Treatment with omalizumab showed effect in terms of reduced number of exacerbations, maintenance therapy and reliever medications. However, no improvement was seen in PFTs.There is room for improved documentation in terms of symptom recording and use of rescue medicationas as well as for better patient education and counselling in order to improve compliance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=asthma" title="asthma">asthma</a>, <a href="https://publications.waset.org/abstracts/search?q=omalizumab" title=" omalizumab"> omalizumab</a>, <a href="https://publications.waset.org/abstracts/search?q=severe%20allergic%20asthma" title=" severe allergic asthma"> severe allergic asthma</a>, <a href="https://publications.waset.org/abstracts/search?q=UAE" title=" UAE"> UAE</a> </p> <a href="https://publications.waset.org/abstracts/39494/omalizumab-therapy-experience-for-asthma-at-zayed-military-hospital-zmh-in-united-arab-emirates" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39494.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Mothers and Moneymakers: A Case Study of How Citizen-Women Shape U.S. Marriage Migration Politics Online</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gina%20Longo">Gina Longo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Social media, internet technology, and affordable travel have created avenues like tourism and internet chatrooms for Western women to meet foreign partners without paid, third-party intermediaries in regions like the Middle East/North Africa (MENA) and Sub-Saharan Africa (SSA), where men from mid-level developing countries meet and marry Western women and try to relocate. Foreign nationals who marry U.S. citizens have an expedited track to naturalization. U.S. immigration officials require that “green card” petitioning couples demonstrate that their relationships are “valid and subsisting” (i.e., for love) and not fraudulent (i.e., for immigration papers). These requirements are ostensibly gender- and racially-neutral, but migration itself is not; black and white women petitioners who seek partners from these regions and solicit advice from similar others about the potential obstacles to their petitions’ success online. Using an online ethnography and textual analysis of conversation threads on a large on-line immigration forum where U.S. petitioners exchange such information, this study examines how gendered and racialized standards of legitimacy are applied to family and sexuality and used discursively online among women petitioners differently to achieve “genuineness” and define “red flags” indicating potential marriage fraud. This paper argues that forum-women members police immigration requests even before cases reach an immigration officer, and use this social media platform to reconstruct gendered and racialized hierarchies of U.S. citizenship. Women petitioners use the formal criteria of U.S. immigration in ways that reveal gender and racial ideologies, expectations for conformity to a gendered hegemonic family ideal, and policing of women’s sexual agency, fertility, and desirability. These intersectional norms shape their online discussions about the suitability of marriages and of the migration of non-citizen male partners of color to the United States. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=marriage%20fraud" title="marriage fraud">marriage fraud</a>, <a href="https://publications.waset.org/abstracts/search?q=migration" title=" migration"> migration</a>, <a href="https://publications.waset.org/abstracts/search?q=online%20forums" title=" online forums"> online forums</a>, <a href="https://publications.waset.org/abstracts/search?q=women" title=" women"> women</a> </p> <a href="https://publications.waset.org/abstracts/96227/mothers-and-moneymakers-a-case-study-of-how-citizen-women-shape-us-marriage-migration-politics-online" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/96227.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">120</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Efforts to Revitalize Piipaash Language: An Explorative Study to Develop Culturally Appropriate and Contextually Relevant Teaching Materials for Preschoolers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shahzadi%20Laibah%20Burq">Shahzadi Laibah Burq</a>, <a href="https://publications.waset.org/abstracts/search?q=Gina%20Scarpete%20Walters"> Gina Scarpete Walters</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Piipaash, representing one large family of North American languages, Yuman, is reported as one of the seriously endangered languages in the Salt River Pima-Maricopa Indian Community of Arizona. In a collaborative venture between Arizona State University (ASU) and Salt River Pima-Maricopa Indian Community (SRPMIC), efforts have been made to revitalize and preserve the Piipaash language and its cultural heritage. The present study is one example of several other language documentation and revitalization initiatives that Humanities Lab ASU has taken. This study was approved to receive a “Beyond the lab” grant after the researchers successfully created a Teaching Guide for Early Childhood Piipaash storybook during their time working in the Humanities Lab. The current research is an extension of the previous project and focuses on creating customized teaching materials and tools for the teachers and parents of the students of the Early Enrichment Program at SRPMIC. However, to determine and maximize the usefulness of the teaching materials with regards to their reliability, validity, and practicality in the given context, this research aims to conduct Environmental Analysis and Need Analysis. Environmental Analysis seeks to evaluate the Early Enrichment Program situation and Need Analysis to investigate the specific and situated requirements of the teachers to assist students in building target language skills. The study employs a qualitative methods approach for the collection of the data. Multiple data collection strategies are used concurrently to gather information from the participants. The research tools include semi-structured interviews with the program administrators and teachers, classroom observations, and teacher shadowing. The researchers utilize triangulation of the data to maintain validity in the process of data interpretation. The preliminary results of the study show a need for culturally appropriate materials that can further the learning of students of the target language as well as the culture, i.e., clay pots and basket-making materials. It was found that the course and teachers focus on developing the Listening and Speaking skills of the students. Moreover, to assist the young learners beyond the classroom, the teachers could make use of send-home teaching materials to reinforce the learning (i.e., coloring books, including illustrations of culturally relevant animals, food, and places). Audio language resources are also identified as helpful additional materials for the parents to assist the learning of the kids. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=indigenous%20education" title="indigenous education">indigenous education</a>, <a href="https://publications.waset.org/abstracts/search?q=materials%20development" title=" materials development"> materials development</a>, <a href="https://publications.waset.org/abstracts/search?q=need%20analysis" title=" need analysis"> need analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=piipaash%20language%20revitalizaton" title=" piipaash language revitalizaton"> piipaash language revitalizaton</a> </p> <a href="https://publications.waset.org/abstracts/156792/efforts-to-revitalize-piipaash-language-an-explorative-study-to-develop-culturally-appropriate-and-contextually-relevant-teaching-materials-for-preschoolers" class="btn btn-primary 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