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expires=' + expires.toGMTString() + '; domain=.' + this.getMasterDomain() + ';'; }, /** * get the master domain based on business rules */ getMasterDomain : function () { // default the master domain var masterDomain = 'thermofisher.com'; // check for alternate domain portion of URL var regexMatch = document.location.hostname.match(/\.(thermofisher)\.(cn)/i); if (regexMatch !== null) { masterDomain = regexMatch[1] + '.' + regexMatch[2]; } return masterDomain; }, /** * Check if init has been initiated once * @type {Boolean} */ initted: false, /** * @return {Array} method returns an array of a given object's key properties */ init: function () { this.page.country = this.getCookie("CK_ISO_CODE") || 'us'; this.page.language = this.getCookie('CK_LANG_CODE') || 'en'; this.page.siteName = 'thermo'; //hard coded this.initMerchandisingData(); this.initUserData(); this.displayDigitalData(); this.formSubmitEvent(); }, //specific function to set type of the page // need specific function to keep page type separate from other page attributes setPageType: function (type) { this.setPageAttribute('type', type); 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max-width: 5760px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysimage_9523 .image-contain" + "," + "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysimage_9523 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><p>The Applied Biosystems  Precision ID NGS System for human identification can help you solve tough cases by getting more information from your challenging samples. Now you have help moving those unknown samples from storage to investigative leads. Adopting next-generation sequencing (NGS) for forensic DNA analysis in your laboratory is simpler than ever when you combine the Ion Chef System and Ion GeneStudio S5 Systems with optimized Precision ID library preparation, template preparation and sequencing kits, and forensically relevant panels.</p><p>With as little as 125 pg of DNA input, you can process unsolved and missing persons cases with NGS in your lab today, with as few as 5 pipetting steps and 45 minutes of hands-on time. </p><p><a href="/sg/en/home/global/forms/next-generation-sequencing-request-form.html"><span class="btn btn-featured">Get a quote</span></a>   <a href="https://players.brightcove.net/3663210762001/default_default/index.html?videoId=6027692869001" target="_blank"><span class="btn btn-primary">Watch the video</span></a>   <a href="https://assets.thermofisher.com/TFS-Assets/GSD/brochures/precisionid-ngs-system-brochure.pdf" target="_blank"><span class="btn btn-primary">View brochure</span></a></p></div></div></div></div><div style="clear:both"></div><div class="heading section"><h2> Simplest targeted NGS workflow </h2></div><div class="well-cmp well-mini well-gray-lighter section"><div class="well well-gray-lighter well-mini"><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="text parbase section"><div class="table-component-wrapper"><table cellpadding="1" cellspacing="0" class="rte-table rte-table-striped" id="table-986827605"><tbody><tr><td><p><b>Construct library</b><br><span class="muted">Hands-on time: 15 minutes<br> Total time: 7 hours<br></span></p></td><td><p><b>Prepare template</b><br><span class="muted">Hands-on time: 15 minutes<br> Total time: 11 hours</span></p></td><td><p><b>Run sequence</b><br><span class="muted">Hands-on time: <15 minutes<br> Total time: as little as 2 hours</span></p></td><td><p><b>Analyze data</b><br><span class="muted">Total time: as little<br> as 5 hours</span></p></td></tr><tr><td class="rte-icon" colspan="2" style="text-align: center;"><img src="/content/dam/LifeTech/global/promotions/images/2018/10-Oct/Precision-ID-panels-Ion-Chef-System-Icon.png" width="60px"></td><td class="rte-icon" style="text-align: center;"><img src="/content/dam/LifeTech/global/promotions/images/2018/10-Oct/Ion-S5-System-Icon.png" width="50px"></td><td class="rte-icon" style="text-align: center;"><img src="/content/dam/LifeTech/global/promotions/images/2018/10-Oct/Converge-Torrent-Suite-System-Icon.png" width="80px"></td></tr><tr><td style="text-align: center;" valign="bottom" class="rte-table-stripe-row"><p> </p><p><span class="muted">Precision ID panels and Ion AmpliSeq Community panels</span></p></td><td style="text-align: center;" valign="bottom" class="rte-table-stripe-row"><p> </p><span class="muted">Ion Chef System</span><p> </p></td><td style="text-align: center;" valign="bottom" class="rte-table-stripe-row"><p> </p><span class="muted">Ion GeneStudio S5 System</span><p> </p></td><td valign="bottom" style="text-align: center;" class="rte-table-stripe-row"><p style="text-align: left;"><span class="muted">Converge Software<br> for mtDNA, STR<br> and SNP analysis</span></p></td></tr></tbody></table></div></div></div></div></div></div></div><div class="text parbase section"><p><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/precision-id-panels.html">Learn more about Precision ID panels ›</a></p><p><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html">Learn more about Community panels ›</a><br></p></div><div class="text parbase section"><div class="table-component-wrapper"><table border="1" cellspacing="0" cellpadding="1" width="491" class="rte-table" id="table-933363137"><tbody><tr><td width="189"><h3>Application  </h3></td><td width="303"><h3>Panel </h3></td></tr><tr><td width="189"><p>Body fluid identification </p></td><td width="303"><p><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#bodyfluid">Ion AmpliSeq Body Fluid Identification DNA and RNA Research Panels</a></p></td></tr><tr><td width="189"><p>Victim Identification, DVI, Missing Persons </p></td><td width="303"><p><a href="/order/catalog/product/A30938">Precision ID mtDNA Whole Genome Panel</a><br><a href="/order/catalog/product/A31443">Precision ID mtDNA Control Region Panel</a><br><a href="/order/catalog/product/A25642">Precision ID Identity Panel</a><br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#hid">Ion AmpliSeq HID Y-SNP Research Panel v1</a><br> Combination: <a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#visage">Ion AmpliSeq VISAGE-Basic Tool Research Panel</a>, <a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#hid">Ion AmpliSeq HID Y-SNP Research Panel v1</a>, and <a href="/order/catalog/product/A30938">Precision ID mtDNA Whole Genome Panel</a></p></td></tr><tr><td width="189"><p>Investigative leads </p></td><td width="303"><p><a href="/order/catalog/product/A25642">Precision ID Ancestry Panel</a><br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#phenotrivium">Ion AmpliSeq PhenoTrivium Panel</a> <br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#visage">Ion AmpliSeq VISAGE-Basic Tool Research Panel</a></p></td></tr><tr><td width="189"><p>Externally visible traits</p></td><td width="303"><p><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#phenotrivium">Ion AmpliSeq PhenoTrivium Panel</a> <br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#visage">Ion AmpliSeq VISAGE-Basic Tool Research Panel</a><br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#dna">Ion AmpliSeq DNA Phenotyping Panel</a></p></td></tr><tr><td width="189"><p>Bio Geographic Ancestry</p></td><td width="303"><p><a href="/order/catalog/product/A25642">Precision ID Ancestry Panel</a><br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#phenotrivium">Ion AmpliSeq PhenoTrivium Panel</a> <br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#visage">Ion AmpliSeq VISAGE-Basic Tool Research Panel</a><br><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#mh74">Ion AmpliSeq MH-74 Plex Research Panel</a></p></td></tr><tr><td width="189"><p>Number of contributors,<br> mixture deconvolution</p></td><td width="303"><p><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html#mh74">Ion AmpliSeq MH-74 Plex Research Panel</a><br><a href="/order/catalog/product/A33114">Precision ID GlobalFiler NGS STR Panels</a></p></td></tr></tbody></table></div></div><div class="accordion section"><div class="accordion" id="7b3187b8d61b4203a616581f4c9a715d" style='margin-bottom: 0;'><div class="parsys"><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#7b3187b8d61b4203a616581f4c9a715d" href="#librarypreparationsequencingkits"><span class="caret"></span> Library preparation & sequencing kits </a></div><div class="accordion-body collapse " id="librarypreparationsequencingkits"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="text parbase section"><p>The <a href="/order/catalog/product/A26435" target="_blank">Applied Biosystems Precision ID Library Kits</a> are specifically designed for rapid generation of targeted sequencing libraries from Precision ID panels. The kits are built on Ion AmpliSeq chemistry, which enables scalable multiplex PCR reactions from tens to thousands of amplicons in a single well using as little as 125 pg of starting DNA. These kits also enable the preparation of barcoded libraries using Ion Xpress Barcode Adapters 1-96 Kits or the IonCode Barcode Adapters 1-384 Kit. The barcoded libraries can be combined and loaded onto a single Ion chip to minimize the sequencing run time and costs, and allow for accurate sample-to-sample comparison. Precision ID Library Kits are for use with manual procedures or with high-throughput robotics platforms.</p><p>The <a href="#" target="_blank">Precision ID DL8 Kit</a> is designed for use with the Ion Chef System for automation of Ion AmpliSeq library construction. Leveraging the automation capabilities of the Ion Chef System, this kit enables the reproducible preparation of Precision ID amplicon libraries, with less than 15 minutes of hands-on time and only 3 liquid transfer steps. Compatible with 1- and 2-pool panel designs, the kit automates the preparation of libraries from 8 samples in a single run, delivering a single tube of pooled libraries ready for downstream templating and sequencing.</p><p>The Ion S5 Precision ID Chef & Sequencing Kit is fully optimized for templating and sequencing of all available HID NGS panels (STR, SNPs, and mitchondrial DNA) on the Ion GeneStudio S5 Systems. The kit is available in two formats: two runs per initialization for higher-throughput labs and one run per initialization for less frequent analyses.</p></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#7b3187b8d61b4203a616581f4c9a715d" href="#templatepreparation"><span class="caret"></span> Automate library & template preparation with the Ion Chef System </a></div><div class="accordion-body collapse " id="templatepreparation"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h3> Automate library and template preparation with the Ion Chef System </h3></div><div class="text parbase section"><p>Save time at the bench, help improve your laboratory’s productivity, and standardize your results. The <a href="https://tools.thermofisher.com/content/sfs/brochures/ion-chef-system-brochure.pdf" target="_blank">Ion Chef System for human identification</a> performs the repetitive lab work without the need for complex robotics and confusing scripts. Paired with Ion Torrent next-generation sequencing platforms, the Ion Chef System automates Precision ID library preparation, template generation, and chip loading with push-button simplicity—enabling DNA to data in as little as 45 minutes of hands-on time.</p></div><div class="heading section"><h3> Ion Chef System templating and chip loading workflow </h3></div><div class="LTRawHTML section"><style> .ctr { margin-left:30px; } .static-workflow2 { -moz-border-radius:5px; -webkit-border-radius:5px; background:#dfdfdf; border-radius:5px; padding:15px 0 15px 7px; } .swf-step2 { -moz-border-radius:5px; -webkit-border-radius:5px; background:#fff; border-radius:5px; float:left; margin-left:13px; padding:10px 25px; width:160px; position:relative; z-index:1; height:270px; _display:inline; } .swf-step-title2 { font-weight:bold; margin-bottom:5px; } .swf-step-title2 b { -moz-border-radius:100px; -webkit-border-radius:100px; background:#ccc; border-radius:100px; color:#fff; text-shadow:0 -1px 1px #bbb; padding: 3px 7px; margin-left:-20px; text-align:center; } .swf-step-img2 { margin-bottom:5px; } .swf-step-arrow2 { background:url(/content/dam/LifeTech/migration/images/sequencing/semiconductor-sequencing/ion-torrent.par.73502.image.gif?direct=1) no-repeat top left; position:absolute; top:100px; left:-13px; z-index:1000; height:64px; width:39px; } </style></div><div class="text parbase section"><div class="static-workflow2 group"><div class="swf-step2"><div class="swf-step-title2"><b>1</b><span>Library preparation</span></div><div class="swf-step-title2">   </div><div class="swf-step-title2" style="text-align: center;">   </div><div class="swf-step-title2" style="text-align: center;"><img src="/content/dam/LifeTech/global/life-sciences/sequencing/Next-Generation%20Sequencing/Ion%20Torrent/Images/Icons/open-ion-chef-125x103.jpg"></div><div class="swf-step-desc2"><ul><li>Load reagents & consumables</li><li>Load library samples</li><li>Set run parameters</li></ul></div></div><div class="swf-step2"><div class="swf-step-arrow2">   </div><div class="swf-step-title2"><b>2</b><span>Automated template preparation and chip loading</span></div><div class="swf-step-title2" style="text-align: center;"><img src="/content/dam/LifeTech/global/life-sciences/sequencing/Next-Generation%20Sequencing/Ion%20Torrent/Images/Icons/chef-sketch-transcriptome.jpg"></div><div class="swf-step-desc2"><ul><li>Library amplification</li><li>ISP recovery & enrichment</li><li>Chip loading</li></ul></div></div><div class="swf-step2"><div class="swf-step-arrow2">   </div><div class="swf-step-title2"><b>3</b><span>Sequencing</span></div><div class="swf-step-title2">   </div><div class="swf-step-img2" style="text-align: center;">   </div><div class="swf-step-img2" style="text-align: center;"><img src="/content/dam/LifeTech/global/life-sciences/sequencing/Next-Generation%20Sequencing/Ion%20Torrent/Images/Icons/pgm-s5.jpg" alt="Ion PGM, Ion S5"><br></div><div class="swf-step-desc2"><p class="caption-text2">Run sequence on:<br></p><ul><li>Ion GeneStudio S5 System</li></ul><p> </p></div></div></div></div><div class="text parbase section"><p>Suitable for scientists and researchers in forensic human identification, the Ion Chef System offers automated workflows that help enable gains in laboratory efficiency. Unleash the power of the Precision ID NGS System with Ion Chef System automation, paired with Ion AmpliSeq technology which is used in the Precision ID Panels for human identification.</p><ul><li>Automates library generation, equalization, and pooling for 1- and 2-pool designs for up to 8 samples in a single instrument run</li><li>Operates with a very low inter-run cross-contamination rate of <0.01%</li><li>Helps reduce sources of variability for forensic scientists of any experience level</li><li>Supports all Ion Torrent semiconductor chips and sequencing chemistries</li></ul></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_7571itemParsysimage_ecb"><a class="image-enlarge-link" data-lightbox="image_ecb" href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/_jcr_content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/backgroundimg.img.jpg/1730741151701.jpg"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.full.high.jpg/1730741151680.jpg' media="(min-width: 1px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.full.high.jpg/1730741151680.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.320.high.jpg/1730741151680.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.480.high.jpg/1730741151680.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.320.medium.jpg/1730741151680.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.620.high.jpg/1730741151680.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.320.low.jpg/1730741151680.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_7571/itemParsys/image_ecb/foregroundimg.img.480.medium.jpg/1730741151680.jpg" alt='template-preparation-showcase-image-230x195' title='template-preparation-showcase-image-230x195'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_7571itemParsysimage_ecb img{ width:100%; max-width: 230px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_7571itemParsysimage_ecb .image-contain" + "," + "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_7571itemParsysimage_ecb .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></a><div class="caption"><small><small><span class="icon-zoom-in"></span> Click image to enlarge</small></small></div></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><p>Comparison of reproducibility across several next-generation sequencing metrics (number of reads, base coverage and loading efficiency) for Ion libraries processed (templating and chip loading) using the Ion Chef and Ion OneTouch 2 Systems. While both systems exhibit excellent reproducibility, the Ion Chef System demonstrates lower coefficient of variation (CV) % values across all metrics.</p></div></div></div></div><div style="clear:both"></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#7b3187b8d61b4203a616581f4c9a715d" href="#simplengsforensics"><span class="caret"></span> Flexible and scalable Ion GeneStudio S5 systems </a></div><div class="accordion-body collapse " id="simplengsforensics"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="heading section"><h3> Fast, flexible, and simple next-generation sequencing for forensics with the Ion GeneStudio S5 Systems </h3></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt3"><div class="parsys_column cq-colctrl-lt3-c0"><div container-id="cq-colctrl-lt3" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_2dcb"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.full.high.jpg/1730741151963.jpg' media="(min-width: 1px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.full.high.jpg/1730741151963.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.320.high.jpg/1730741151963.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.480.high.jpg/1730741151963.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.320.medium.jpg/1730741151963.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.620.high.jpg/1730741151963.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.320.low.jpg/1730741151963.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_2dcb/foregroundimg.img.480.medium.jpg/1730741151963.jpg" alt='Ion GeneStudio S5 System' title='Ion GeneStudio S5 System'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_2dcb img{ width:100%; max-width: 251px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_2dcb .image-contain" + "," + "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_2dcb .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div><div container-id="cq-colctrl-lt3" comp-id="A2"><div class="heading section"><h4><a href="/order/catalog/product/A27212">Ion GeneStudio S5 System</a></h4></div></div></div><div class="parsys_column cq-colctrl-lt3-c1"><div container-id="cq-colctrl-lt3" comp-id="B1"><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_ce34"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.full.high.jpg/1730741152008.jpg' media="(min-width: 1px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.full.high.jpg/1730741152008.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.320.high.jpg/1730741152008.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.480.high.jpg/1730741152008.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.320.medium.jpg/1730741152008.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.620.high.jpg/1730741152008.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.320.low.jpg/1730741152008.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_ce34/foregroundimg.img.480.medium.jpg/1730741152008.jpg" alt='Ion GeneStudio S5 System' title='Ion GeneStudio S5 System'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_ce34 img{ width:100%; max-width: 251px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_ce34 .image-contain" + "," + "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_ce34 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div><div container-id="cq-colctrl-lt3" comp-id="B2"><div class="heading section"><h4><a href="/order/catalog/product/A27214">Ion GeneStudio S5 Plus System</a></h4></div></div></div><div class="parsys_column cq-colctrl-lt3-c2"><div container-id="cq-colctrl-lt3" comp-id="C1"><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_171d"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.full.high.jpg/1730741152054.jpg' media="(min-width: 1px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.full.high.jpg/1730741152054.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.320.high.jpg/1730741152054.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.480.high.jpg/1730741152054.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.320.medium.jpg/1730741152054.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.620.high.jpg/1730741152054.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.320.low.jpg/1730741152054.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_171d/foregroundimg.img.480.medium.jpg/1730741152054.jpg" alt='Ion GeneStudio S5 System' title='Ion GeneStudio S5 System'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_171d img{ width:100%; max-width: 276px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_171d .image-contain" + "," + "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_171d .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div><div container-id="cq-colctrl-lt3" comp-id="C2"><div class="heading section"><h4><a href="/order/catalog/product/A27214">Ion GeneStudio Prime System</a></h4></div></div></div></div><div style="clear:both"></div><div class="text parbase section"><p>Want to sequence SNP panels on Monday, mtDNA panels on Wednesday, and STR panels on Thursday? The Ion GeneStudio S5 Systems, an integral part of the <a href="/content/dam/LifeTech/Documents/PDFs/HID-Precision-ID-System-Brochure.pdf" target="_blank">Precision ID NGS System</a>, let you leverage a single benchtop instrument that scales to your application and throughput needs. The Ion GeneStudio S5 Systems provide the simplest DNA-to-data workflow for targeted sequencing with industry-leading speed and affordability, and the flexibility to multiplex and optimize the number of samples and panels on a single chip.</p><h3>Simplicity: ready, set, sequence</h3><ul><li>Less than 15 minutes of sequencer hands-on time</li><li>Less than 45 minutes of hands-on time for a DNA-to-data targeted sequencing workflow</li></ul><h3>Speed: because every hour counts</h3><ul><li><2.5 hours for a sequencing run</li><li>From DNA to data in less than 2 days with an overnight Ion Chef templating run</li></ul></div><div class="text parbase section"><div class="table-component-wrapper"><table border="1" cellpadding="0" cellspacing="0" width="1264" class="rte-table rte-table-striped" id="table--1398007674"><tbody><tr><td colspan="2" height="20" width="374"> </td><td colspan="3" width="305" style="text-align: center;"><b>Ion GeneStudio S5 System</b></td><td colspan="3" width="293" style="text-align: center;"><b>Ion GeneStudio S5 Plus System</b></td><td colspan="3" width="292" style="text-align: center;"><b>Ion GeneStudio S5 Prime System</b></td></tr><tr><td height="20"> </td><td> </td><td>Ion 510 Chip</td><td>Ion 520 Chip</td><td>Ion 530 Chip</td><td>Ion 510 Chip</td><td>Ion 520 Chip</td><td>Ion 530 Chip</td><td>Ion 510 Chip</td><td>Ion 520 Chip</td><td>Ion 530 Chip</td></tr><tr><td height="20"><b>Reads</b></td><td> </td><td>2-3 million</td><td>4-6 million</td><td>15-20 million</td><td>2-3 million</td><td>4-6 million</td><td>15-20 million</td><td>2-3 million</td><td>4-6 million</td><td>15-20 million</td></tr><tr><td rowspan="5" height="100" width="161"><b>Turnaround time (sequencing + analysis)</b></td><td>mtDNA whole genome panel</td><td>-</td><td>7.5 hr</td><td>10.5 hr</td><td>-</td><td>3.5 hr</td><td>5 hr</td><td>-</td><td>3 hr</td><td>4 hr</td></tr><tr><td height="20">mtDNA control regions panel</td><td>4.5 hr</td><td>7.5 hr</td><td>-</td><td>3 hr</td><td>3.5 hr</td><td>-</td><td>3 hr</td><td>3 hr</td><td>-</td></tr><tr><td height="20">Ancestry panel</td><td>4.5 hr</td><td>7.5 hr</td><td>10.5 hr</td><td>3 hr</td><td>3.5 hr</td><td>5 hr</td><td>3 hr</td><td>3 hr</td><td>4 hr</td></tr><tr><td height="20">Identity panel</td><td>4.5 hr</td><td>7.5 hr</td><td>10.5 hr</td><td>3 hr</td><td>3.5 hr</td><td>5 hr</td><td>3 hr</td><td>3 hr</td><td>4 hr</td></tr><tr><td height="20">STR panel</td><td>-</td><td>12.5 hr</td><td>22.5 hr</td><td>-</td><td>4.5 hr</td><td>5.5 hr</td><td>-</td><td>4 hr</td><td>5 hr</td></tr></tbody></table></div></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt8"><div class="parsys_column cq-colctrl-lt8-c0"><div container-id="cq-colctrl-lt8" comp-id="A1"><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_d86a"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.full.high.jpg/1730741152149.jpg' media="(min-width: 1px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.full.high.jpg/1730741152149.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.320.high.jpg/1730741152149.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.480.high.jpg/1730741152149.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.320.medium.jpg/1730741152149.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.620.high.jpg/1730741152149.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.320.low.jpg/1730741152149.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_d86a.img.480.medium.jpg/1730741152149.jpg" alt='simple-ngs-sample-input-image-230x195' title='simple-ngs-sample-input-image-230x195'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_d86a img{ width:100%; max-width: 230px; } </style><script type="text/javascript"> $( document ).ready(function() { if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div></div><div class="parsys_column cq-colctrl-lt8-c1"><div container-id="cq-colctrl-lt8" comp-id="B1"><div class="text parbase section"><h3>Small sample input: because every sample matters</h3><ul><li>As little as 125 pg DNA needed to generate human identification profiles</li></ul></div></div></div></div><div style="clear:both"></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt0"><div class="parsys_column cq-colctrl-lt0-c0"><div container-id="cq-colctrl-lt0" comp-id="A1"><div class="text parbase section"><h3>Scalability: single sequencer, multiple applications</h3><ul><li>Analyze SNPs, mtDNA, STRs and mRNA targets</li><li>Multiple chip formats and read lengths to match your throughput needs </li><li>Flexible multiplexing of samples and panels on a single chip</li></ul></div></div></div><div class="parsys_column cq-colctrl-lt0-c1"><div container-id="cq-colctrl-lt0" comp-id="B1"><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_6ba4itemParsysimage_cf7a"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_6ba4/itemParsys/image_cf7a.img.full.high.jpg/1730741152194.jpg' media="(min-width: 1px)"><img 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than 3,700 global sales, service, and technical support specialists are available to assist you in person, by phone, or online—including our Human Identification Professional Services (HPS) team that can help you successfully navigate the validation process required to bring new technologies into your lab.</li></ul><p> </p><p>New to next-generation sequencing? <a href="/sg/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-s5-ngs-targeted-sequencing/ion-s5-demo-videos.html">Watch the demos for each step of the Ion Torrent next-generation sequencing workflow.</a></p></div></div><div container-id="cq-colctrl-lt7" comp-id="A2"><div class="brightcoveplayer section"><div data-video="dc46d3836c7f"><script type="text/javascript"> var loadEME = true; function checkVideojsLoaded(callback, schemaVideoId, maxIterations) { let iterations = 0; return new Promise((resolve, reject) => { 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Additionally, full auditing functionality is included for chain-of-custody requirements.</p></div><div class="heading section"><h3> mtDNA analysis </h3></div><div comp-order="bycol" class="parsys_column cq-colctrl-lt0"><div class="parsys_column cq-colctrl-lt0-c0"><div container-id="cq-colctrl-lt0" comp-id="A1"><div class="text parbase section"><p>Analysis of the mtGenome can be challenging due to complex alignments, the presence mtDNA heteroplasmy, and insertions and deletions present throughout the genome that may impact the accuracy of variant calling. NGS reads from the BAM files are first mapped to nodes in PhyloTree and then realigned using a custom Smith–Waterman alignment algorithm that integrates PhyloTree and EMPOP information into the scoring function. Variants are called with reference to the rCRS. Additionally, the closest haplogroup is calculated, and variants are evaluated based on their occurrence in the haplogroup as well as other general metrics including frequency, strand bias, and coverage. Variants can be viewed in a variety of formats, including a circular plot, linear view, grid, or IGV format. In addition, profiles can be compared as well as downloaded in CODIS format.</p></div></div></div><div class="parsys_column cq-colctrl-lt0-c1"><div container-id="cq-colctrl-lt0" comp-id="B1"><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_9a73"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.320.medium.jpg/1730741152363.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.480.high.jpg/1730741152363.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.620.high.jpg/1730741152363.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.full.high.jpg/1730741152363.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.320.high.jpg/1730741152363.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.480.high.jpg/1730741152363.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.320.medium.jpg/1730741152363.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.620.high.jpg/1730741152363.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.320.low.jpg/1730741152363.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_9a73/foregroundimg.img.480.medium.jpg/1730741152363.jpg" alt='Figure 7' title='Figure 7'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_9a73 img{ width:100%; max-width: 639px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_9a73 .image-contain" + "," + "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_9a73 .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div></div></div><div style="clear:both"></div><div class="heading section"><h3> STR analysis </h3></div><div class="text parbase section"><p>With an interface similar to that of Applied Biosystems GeneMapper ID-X Software, you will be able to quickly evaluate sequencing data using familiar process quality values (PQV) and flags such as allele number (AN), off-ladder allele (OL), peak height ratio (PHR), below stochastic threshold (BST), and control concordance (CC) (use figure). Preconfigured analysis settings are provided within the NGS module and may be modified by the laboratory as needed. </p></div><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_62ef"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.320.low.jpg/1730741152403.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.320.medium.jpg/1730741152403.jpg' media="(min-width: 320px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.480.medium.jpg/1730741152403.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.620.high.jpg/1730741152403.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.full.high.jpg/1730741152403.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.320.high.jpg/1730741152403.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.480.high.jpg/1730741152403.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.320.medium.jpg/1730741152403.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.620.high.jpg/1730741152403.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.320.low.jpg/1730741152403.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_62ef/foregroundimg.img.480.medium.jpg/1730741152403.jpg" alt='Figure3-COL03980' title='Figure3-COL03980'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_62ef img{ width:100%; max-width: 870px; } </style><script type="text/javascript"> $( document ).ready(function() { // apply fillIt plugin var fillClasses = "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_62ef .image-contain" + "," + "#cq-image-jsp-"+"074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_62ef .image-cover" ; // Due to the issue explained below, we are binding 'one' instead of 'on' and we need it only once. $(fillClasses).load(function() { $(this).fillIt(); }); // Force load image to avoid cache issue, a bug which makes image reset height when having more than one image/image-text components on the same page and rendering after edit. $(fillClasses).each(function(){ if(this.complete){ $(this).load(); } }); if(!!window.picturefill){ window.picturefill(); } }); </script></div></div><div class="heading section"><h3> SNP analysis </h3></div><div class="text parbase section"><p>Converge Software SNP analysis provides a variety of metrics to monitor sequencing quality, including coverage of aligned reads to a hotspot, strand bias, number of reads containing each base at the hotspot, genotype call and quality, and major allele frequency. Tertiary ancestry analysis consists of generating an estimation of admixture prediction and population likelihoods with variability estimates based on bootstrapping analysis (Alexander et al., Genome Research, 2009). Identity analysis calculating random match probability (RMP) can be based on genotype frequencies generated from 1000 Genomes data or from user-supplied population frequency data as well as a Y haplogroup prediction.</p></div><div class="image parbase section"><div id="cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_df57"><picture><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.320.low.jpg/1730741152440.jpg' media="(min-width: 1px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.320.medium.jpg/1730741152440.jpg' media="(min-width: 320px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.480.medium.jpg/1730741152440.jpg' media="(min-width: 490px)"><source srcset='https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.620.high.jpg/1730741152440.jpg' media="(min-width: 630px)"><img srcset="https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.full.high.jpg/1730741152440.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.320.high.jpg/1730741152440.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.480.high.jpg/1730741152440.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.320.medium.jpg/1730741152440.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.620.high.jpg/1730741152440.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.320.low.jpg/1730741152440.jpg,https://www.thermofisher.com/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/accordion_ef85/itemspar/accordionitem_10cf/itemParsys/image_df57.img.480.medium.jpg/1730741152440.jpg" alt='new-figure-ancestry-snp_admixture_result-small' title='new-figure-ancestry-snp_admixture_result-small'></picture><style> #cq-image-jsp-074635ab-a14c-45b1-a07f-2986763b6e1cMainParsysaccordion_ef85itemsparaccordionitem_10cfitemParsysimage_df57 img{ width:100%; max-width: 800px; } </style><script type="text/javascript"> $( document ).ready(function() { if(!!window.picturefill){ window.picturefill(); } }); </script></div></div></div></div></div></div></div></div><div class="accordionitem section"><div class='accordion-group' ><div class='accordion-heading '><a class="accordion-toggle" data-toggle="collapse" data-parent="#7b3187b8d61b4203a616581f4c9a715d" href="#human"><span class="caret"></span> Human Identification NGS publications </a></div><div class="accordion-body collapse " id="human"><div class="accordion-inner"><div class="accordion-content"><div class="itemParsys parsys"><div class="text parbase section"><h3>Precision ID mtDNA panels</h3><p>Kocsis, Balázs et al. (2024) <a href="https://www.fsigenetics.com/article/S1872-4973(24)00155-8/fulltext" target="_blank">Internal validation of the Precision ID GlobalFiler NGS STR panel v2 kit with locus-specific analytical threshold, and with special regard to mixtures and low template DNA detection.</a> Forensic Science International: Genetics, Volume 74, 103159</p><p>Liu, J et al. (2023) <a href="https://www.sciencedirect.com/science/article/abs/pii/S0379073823001585" target="_blank">Exploring rare differences in mitochondrial genome between MZ twins using Ion Torrent semiconductor sequencing.</a> Forensic Sci Int. 348:111708.</p><p>Faccinetto, C et al. (2021) <a href="https://link.springer.com/article/10.1007/s00414-021-02686-w" target="_blank">Internal validation and improvement of mitochondrial genome sequencing using the Precision ID mtDNA Whole Genome Panel.</a> Int J Legal Med 135(6):2295-2306.</p><p>Ta, MTA at al. (2021) <a href="https://pubmed.ncbi.nlm.nih.gov/34196785/" target="_blank">Massively parallel sequencing of human skeletal remains in Vietnam using the precision ID mtDNA control region panel on the Ion S5 system.</a> Int J Legal Med. 135(6):2285-2294.</p><h3>Precision ID Ancestry panel</h3><p>Resutik, P et al (2023) <a href="https://www.sciencedirect.com/science/article/pii/S187249732300025X" target="_blank">Comparative evaluation of the MAPlex, Precision ID Ancestry Panel, and VISAGE Basic Tool for biogeographical ancestry inference.</a> Forensic Sci Int Genet. 64:102850.</p><p>Truelsen D et al (2021) <a href="https://www.nature.com/articles/s41598-021-97654-0" target="_blank">Assessment of the effectiveness of the EUROFORGEN NAME and Precision ID Ancestry panel markers for ancestry investigations.</a> Sci Rep;11(1):18595</p><p>Köksal, Z et al (2023) <a href="https://www.fsigenetics.com/article/S1872-4973(23)00109-6/fulltext" target="_blank">Pitfalls and challenges with population assignments of individuals from admixed populations: Applying Genogeographer on Brazilian individuals.</a> Forensic Sci Int Genet 67:102934</p><p>Jin, S et al (2018) <a href="https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/elps.201800171" target="_blank">Implementing a biogeographic ancestry inference service for forensic casework.</a> Electrophoresis. 39(21):2757-2765</p><h3>Precision ID Identity panel</h3><p>Yang, SB et al (2023) <a href="https://europepmc.org/article/med/37440105" target="_blank">Forensic genetic analysis of single-nucleotide polymorphisms and microhaplotypes in Koreans through next-generation sequencing using precision ID identity panel.</a> Genes Genomics. 45(10):1281-1293</p><p>Zupanič Pajnič, I et al (2023) <a href="https://europepmc.org/article/MED/37127762" target="_blank">Improving kinship probability in analysis of ancient skeletons using identity SNPs and MPS technology.</a> Int J Legal Med. 137(4):1007-1015</p><p>Tiedge, TM et al (2021) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1355030621000678" target="_blank">High-throughput DNA sequencing of environmentally insulted latent fingerprints after visualization with nanoscale columnar-thin-film technique.</a> Sci Justice. 61(5):505-515</p><p>Turchi, C  et al (2020) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1872497320301721" target="_blank">Assessment of the Precision ID Identity Panel kit on challenging forensic samples.</a> Forensic Sci Int Genet. 49:102400</p><h3>Precision ID GlobalFiler NGS STR panel</h3><p>Ohuchi, T et al (2022) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1344622322001390" target="_blank">Allele frequencies of 31 autosomal short tandem repeat (auSTR) loci obtained using the Precision ID GlobalFiler NGS STR Panel v2 in 322 individuals from the Japanese population.</a> Leg Med (Tokyo). 59:102151<br><br> Zupanič Pajnič, I et al (2022) <a href="https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/elps.202100143" target="_blank">Isometric artifacts from polymerase chain reaction-massively parallel sequencing analysis of short tandem repeat loci: An emerging issue from a new technology?</a> .Electrophoresis. 43(13-14):1521-1530<br><br> Ragazzo M et al (2020) <a href="https://www.mdpi.com/2073-4425/11/6/591" target="_blank">Interpreting Mixture Profiles: Comparison between Precision ID GlobalFiler NGS STR Panel v2 and Traditional Methods.</a> Genes (Basel). 11(6):591</p><p>Zupanič Pajnič, I et al (2020) <a href="https://www.sciencedirect.com/science/article/abs/pii/S0379073819304682" target="_blank">Identifying victims of the largest Second World War family massacre in Slovenia.</a> Forensic Sci Int. 306:110056</p><h3>Community panels<b><u></u></b></h3><h4>Ion AmpliSeq PhenoTrivium Panel</h4><p>Diepenbroek, M et al (2023) <a href="https://www.fsigenetics.com/article/S1872-4973(23)00113-8/fulltext" target="_blank">Phenotype predictions of two-person mixture using single cell analysis.</a> Forensic Sci Int Genet 67:102938</p><p>Diepenbroek, M et al (2020) <a href="https://www.mdpi.com/2073-4425/11/12/1398" target="_blank">Evaluation of the Ion AmpliSeq PhenoTrivium Panel: MPS-Based Assay for Ancestry and Phenotype Predictions Challenged by Casework Samples.</a> Genes (Basel) 11(12):1398</p><p>Diepenbroek, M et al (2021) <a href="https://www.mdpi.com/2073-4425/12/9/1362" target="_blank">Pushing the Boundaries: Forensic DNA Phenotyping Challenged by Single-Cell Sequencing.</a> Genes (Basel). 12(9):1362</p><h4>Ion AmpliSeq VISAGE-Basic Tool Research Panel</h4><p>Xavier, C  et al (2020) <a href="https://www.fsigenetics.com/article/S1872-4973(20)30109-5/fulltext" target="_blank">Development and validation of the VISAGE AmpliSeq basic tool to predict appearance and ancestry from DNA.</a> Forensic Sci Int Genet. 48:102336</p><h4>Ion AmpliSeq DNA Phenotyping Panel</h4><p>Inkret, J, et al (2023) <a href="https://www.mdpi.com/2073-4425/14/7/1449" target="_blank">A Multisample Approach in Forensic Phenotyping of Chronological Old Skeletal Remains Using Massive Parallel Sequencing (MPS) Technology.</a> Genes (Basel). 14(7):1449</p><p>Kukla-Bartoszek, M et al (2020) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1872497320300740" target="_blank">The challenge of predicting human pigmentation traits in degraded bone samples with the MPS-based HIrisPlex-S system.</a> Forensic Sci Int Genet. 47:102301</p><p>Melchionda, F et al (2022) <a href="https://www.mdpi.com/2073-4425/13/10/1688" target="_blank">Development and Validation of MPS-Based System for Human Appearance Prediction in Challenging Forensic Samples.</a> Genes (Basel). 13(10):1688</p><p>Breslin, K  et al (2019) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1872497319302054" target="_blank">HIrisPlex-S system for eye, hair, and skin color prediction from DNA: Massively parallel sequencing solutions for two common forensically used platforms.</a> Forensic Sci Int Genet. 43:102152</p><h4>Ion AmpliSeq MH-74 Plex Research Panel</h4><p>Oldoni, F et al (2020) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1872497320301708" target="_blank">Population genetic data of 74 microhaplotypes in four major U.S. population groups.</a> Forensic Sci Int Genet. 49:102398</p><p>Oldoni, F et al (2020) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1872497320301393" target="_blank">A sequence-based 74plex microhaplotype assay for analysis of forensic DNA mixtures.</a> Forensic Sci Int Genet. 49:102367</p><h4>Ion AmpliSeq HID Y-SNP Research Panel v1</h4><p>Köksal, Z et al (2022) <a href="https://www.fsigenetics.com/article/S1872-4973(22)00049-7/fulltext" target="_blank">Testing the Ion AmpliSeq HID Y-SNP Research Panel v1 for performance and resolution in admixed South Americans of haplogroup Q.</a> Forensic Sci Int Genet. 59:102708</p><p>Ochiai, E  et al (2016) <a href="https://www.sciencedirect.com/science/article/abs/pii/S1344622316300748" target="_blank">Evaluation of Y chromosomal SNP haplogrouping in the HID-Ion AmpliSeq Identity Panel.</a> Leg Med (Tokyo). 22:58-61</p><p>Wang M et al (2019) <a href="https://www.fsigenetics.com/article/S1872-4973(18)30261-8/fulltext" target="_blank">Developmental validation of a custom panel including 165 Y-SNPs for Chinese Y-chromosomal haplogroups dissection using the ion S5 XL system.</a> Forensic Sci Int Genet. 38:70-76</p><p>Ralf, A et al (2019) .<a href="https://www.fsigenetics.com/article/S1872-4973(19)30020-1/fulltext#" target="_blank">Forensic Y-SNP analysis beyond SNaPshot: High-resolution Y-chromosomal haplogrouping from low quality and quantity DNA using Ion AmpliSeq and targeted massively parallel sequencing</a>. Forensic Sci Int Genet 41:93-106 </p></div></div></div></div></div></div></div></div></div><script> $j(document).ready(function(){ $j('#7b3187b8d61b4203a616581f4c9a715d').on('hide', function(e) { $(e.target).find(".accordion-content").hide(); }); $j('#7b3187b8d61b4203a616581f4c9a715d').on('show', function(e) { $(e.target).find(".accordion-content").show(); }); }); </script></div><div class="text parbase section"><p><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/customer-videos.html"><b>Watch customer videos and webinars ›</b></a></p></div><div class="productlist parbase section"><div id="skulist" style="display:none">A35984,A35985,A35986,A33114,A33212,A33208,A35850,A33586,4474517,A29751,A25643,A25642,A26808,A26807,A30938,A31443,A30941,A26435,474009,474518,474519,474520,474521,474517,A29751,4468802,A27762,A27764,A34292,A35131,A35987,A36237</div><div id='ltajax-5881868903415851364'></div><script type="text/javascript">(function() {$('#ltajax-5881868903415851364').load('/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/jcr:content/MainParsys/productlist_55a6.ajax.html?skulist=');})(); </script></div><div class="well-cmp section"><div class="well "><div class="well-container" style=""><div class="well-content"><div class="parsys"><div class="heading section"><h2> Resources </h2></div><div class="text parbase section"><h3>Documents</h3><ul class="the-icons clearfix"><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/brochures/precisionid-ngs-system-brochure.pdf">Brochure: Precision ID NGS System</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Product-Bulletins/converge-software-productbulletin.pdf">Converge Software Product Bulletin</a></li><li><span class="icon icon-pdf"></span><a href="/content/dam/LifeTech/Documents/PDFs/HID-IonChef-Flyer.pdf">Brochure: Ion Chef System</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Flyers/precisionid-ancestry-snp-flyer.pdf">Flyer: Precision ID Ancestry Panel</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Flyers/precisionid-identity-snp-flyer.pdf">Flyer: Precision ID Identity Panel</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Flyers/precisionid-globalfiler-ngs-str-flyer.pdf">Flyer: Precision ID GlobalFiler NGS STR Panel</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Flyers/precisionid-mtDNA-panel-flyer.pdf">Flyer: Solutions for mtDNA analysis</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/brochures/hid-integrated-solutions-brochure.pdf">Brochure: Integrated human identification (HID) solutions</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Reference-Materials/hid_seqstudio_ngs_forensic_dna_analysis_customer_profile.pdf">Customer Profile: Capillary electrophoresis (CE) and next-generation sequencing (NGS) applications in forensic DNA analysis</a></li></ul><h3>Technical notes</h3><ul class="the-icons clearfix"><li><span class="icon icon-pdf"></span><a href="/TFS-Assets/GSD/Technical-Notes/hid_ion_ampliseq_body_fluid_ID_technical_note.pdf">Technical Note: Analysis of the Ion AmpliSeq™ Body Fluid Identification RNA and DNA Research Panels</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Technical-Notes/precision_id_str_snp_combo_2019_technical_note.pdf">Technical Note: Precision ID STR and SNP Combination NGS Workflow</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Technical-Notes/hid_ion_ampliseq_mh74_plex_microhaplotype_technical_note.pdf">Technical Note: The Ion AmpliSeq MH-74 Plex Microhaplotype Research Panel</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Technical-Notes/hid_ion_ampliseq_visage_technical_note.pdf">Technical Note: The Ion AmpliSeq VISAGE (Visible Attributes through Genomics) Basic Tool Research Panel</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Technical-Notes/globalfiler-ngs-str-panel-v2-technical-note.pdf">Technical Note: GlobalFiler NGS STR Panel v2</a></li><li><span class="icon icon-pdf"></span><a href="https://assets.thermofisher.com/TFS-Assets/GSD/Application-Notes/hid-ngs-globalfiler-str-analysis-app-note.pdf" target="_blank">Application Note: Get more information from challenging samples with next-generation sequencing of short tandem repeats</a></li></ul><h3>Education</h3><ul class="the-icons clearfix"><li><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/customer-videos.html">Customer videos and webinars</a></li><li><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/precision-id-panels.html">Precision ID panels</a></li><li><a href="/sg/en/home/industrial/forensics/human-identification/forensic-dna-analysis/dna-analysis/next-generation-sequencing-ngs-forensics/ion-ampliseq-community-panels.html">Community panels</a></li><li><a href="/sg/en/home/industrial/forensics/forensics-learning-center/forensics-resource-library/human-identification.html">Human Identification Resources</a></li></ul></div></div></div></div></div></div><div class="text parbase section"><p><a name="prods"></a></p></div><div class="text parbase section"><p class="legal-text">For Research Forensic or Paternity Use Only. 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