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UZ Leuven and KU Leuven invest 14 million euros in new cell and gene therapy facility | UZ Leuven
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At this facility, they want to develop pioneering therapies themselves from the end of 2025 and produce personalised treatments for individual patients " /> <meta property="og:description" content="UZ Leuven and KU Leuven are establishing an innovative facility for the production of Advanced Therapy Medicinal Products (ATMPs) on the Gasthuisberg Campus. At this facility, they want to develop pioneering therapies themselves from the end of 2025 and produce personalised treatments for individual patients " /> <meta property="og:image" content="https://wmimages.uzleuven.be/styles/e22cb3eafdd54a57844ed34d1de56912a49c9848/2024-10/celtherapie_1.jpg?style=W3sicmVzaXplIjp7ImZpdCI6Imluc2lkZSIsIndpZHRoIjoxMjAwLCJoZWlnaHQiOjYzMCwid2l0aG91dEVubGFyZ2VtZW50Ijp0cnVlfX1d&sign=37d6569f6f3b24592a178e73ebc98824764d9acbcf170c6d4c0a9312f44265c8" /> <meta property="og:image:secure_url" content="https://wmimages.uzleuven.be/styles/e22cb3eafdd54a57844ed34d1de56912a49c9848/2024-10/celtherapie_1.jpg?style=W3sicmVzaXplIjp7ImZpdCI6Imluc2lkZSIsIndpZHRoIjoxMjAwLCJoZWlnaHQiOjYzMCwid2l0aG91dEVubGFyZ2VtZW50Ijp0cnVlfX1d&sign=37d6569f6f3b24592a178e73ebc98824764d9acbcf170c6d4c0a9312f44265c8" /> <meta property="og:image:type" content="image/png" /> <meta property="og:image:width" content="1200" /> <meta property="og:image:height" content="630" /> <link rel="stylesheet" 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Please update to the most recent version of your browser, or use another browser like <a data-fragment="" href="https://www.google.nl/intl/nl/chrome/?brand=CHBD&gclsrc=aw.ds&&gclid=EAIaIQobChMI5sqI8cj76AIV2eR3Ch31RA_tEAAYASAAEgLILPD_BwE">Google Chrome</a>.</p> </div> </div> </div> </div> </div> <main class="l-page__content"> <div data-drupal-messages-fallback class="hidden"></div> <nav class="breadcrumb hero__breadcrumb" aria-label="Breadcrumb"> <ol class="breadcrumb__list"> <li class="breadcrumb__item"><a class="breadcrumb__link" href="/en"><span class="breadcrumb__link__text">Home</span></a> <span class="breadcrumb__icon" aria-hidden="true"></span> </li> <li class="breadcrumb__item"><a class="breadcrumb__link" href="/en/news"><span class="breadcrumb__link__text">News</span></a> </li> <li class="breadcrumb__item"> <a class="visually-hidden" aria-current="page">UZ Leuven and KU Leuven invest 14 million euros in new cell and gene therapy facility</a></li> </ol> </nav> <header class="hero is-none"> <div class="hero__content"> <h1 class="hero__title header-hero "> <span class="hero__title__text">UZ Leuven and KU Leuven invest 14 million euros in new cell and gene therapy facility</span> </h1> <div class="hero__date meta">8 October 2024</div> <div class="hero__intro text ">UZ Leuven and KU Leuven are establishing an innovative facility for the production of Advanced Therapy Medicinal Products (ATMPs) on the Gasthuisberg Campus. At this facility, they want to develop pioneering therapies themselves from the end of 2025 and produce personalised treatments for individual patients </div> </div> </header> <div class="l-content"> <article class="l-content__cbs "> <div class="cbs "> <div id="9ba00b80-038b-4754-9534-4cebd74425e5" class="block--text text"> <p>Many diseases are caused by genetic defects or the absence of a certain functional gene. Gene therapy can repair a patient's genetic material or shut down a disease gene. In cell-based therapies, the patient's own immune cells are genetically modified and replaced. With its own ATMP facility, UZ Leuven will be able to modify a patient's own immune cells, bringing benefits to doctors and patients.</p> </div> <div id="42114161-4ab0-4a1d-bfbf-2fc2e3b5f493" class="block--text text"> <p>Cell and gene therapy are already successfully used today for certain cancers, neurodegenerative diseases, metabolic diseases and rare genetic disorders. An in-house cell and gene therapy facility will offer new perspectives for patients with rare genetic disorders and cancers that are hard to treat.</p><p><strong>Accelerate ATMP development</strong></p><p>Cell and gene therapy drugs fall under the heading of Advanced Therapy Medicinal Products (ATMPs). Their production requires a specialised infrastructure with strict regulations and specifically trained staff. The development process of an ATMP is complex, which is why pharmaceutical companies are often not interested in funding experimental drugs in the early stages. Cell and gene therapy are especially important for patients in whom conventional treatments fail. They can provide a solution in diseases for which no treatments exist or for which existing treatments do not catch on. In certain cases, gene or cell therapy can even cure a disease completely. With Leuven's own production facility, immunotherapy will become much easier logistically for both doctor and patient.</p> </div> <blockquote class="quote" id="treatments-with-cell-and-gene-therapy-are-especially-important-for-patients-in-whom-conventional-treatments-do-not-work"> <div class="quote__content quote__content--no-image"> <svg class="quote__quotemark" width="50" height="36" xmlns="http://www.w3.org/2000/svg"><path d="M10.976 13.09c6.034 0 10.926 5.13 10.926 11.455C21.902 30.872 17.01 36 10.976 36 4.94 36 .049 30.872.049 24.545L0 22.91C0 10.257 9.784 0 21.854 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.413 16.413 0 0 0-1.553 1.893c.558-.092 1.13-.14 1.713-.14zm28.097 0C45.108 13.09 50 18.22 50 24.546 50 30.872 45.108 36 39.073 36c-6.034 0-10.927-5.128-10.927-11.455l-.048-1.636C28.098 10.257 37.882 0 49.95 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.404 16.404 0 0 0-1.552 1.893c.558-.092 1.13-.14 1.712-.14z" fill="#007ACC" fill-rule="nonzero"/></svg> <div class="quote__text"> Treatments with cell and gene therapy are especially important for patients in whom conventional treatments do not work. </div> </div> </blockquote> <div id="204ba361-2c5b-4141-bac1-826623848b70" class="block--text text"> <p>UZ Leuven will build the new facility on Gasthuisberg Campus, together with KU Leuven and KU Leuven Research & Development. The new centre of expertise should be ready in the second half of 2025, and the manufacturing facility will meet the strict quality standards of Good Manufacturing Practice (GMP). Successful tandems between committed doctors at UZ Leuven and specialised basic researchers at KU Leuven can lead to innovative therapies for an international patient population.</p><p><strong>Bart Geers, investment manager at KU Leuven Research & Development</strong>: ‘<em>By investing in our own ATMP facility, we are setting up a unique hub. It will allow us to support researchers, clinicians, professors and scientists to turn their project ideas into clinical applications. With a new infrastructure, we will produce advanced or experimental cell therapies to industry standards at the hospital. New therapy options will be available to patients faster.'</em></p> </div> <blockquote class="quote" id="by-taking-the-reins-into-our-own-hands-we-can-respond-more-quickly-to-new-scientific-discoveries"> <div class="quote__content "> <svg class="quote__quotemark" width="50" height="36" xmlns="http://www.w3.org/2000/svg"><path d="M10.976 13.09c6.034 0 10.926 5.13 10.926 11.455C21.902 30.872 17.01 36 10.976 36 4.94 36 .049 30.872.049 24.545L0 22.91C0 10.257 9.784 0 21.854 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.413 16.413 0 0 0-1.553 1.893c.558-.092 1.13-.14 1.713-.14zm28.097 0C45.108 13.09 50 18.22 50 24.546 50 30.872 45.108 36 39.073 36c-6.034 0-10.927-5.128-10.927-11.455l-.048-1.636C28.098 10.257 37.882 0 49.95 0v6.545c-4.17 0-8.09 1.703-11.038 4.793a16.404 16.404 0 0 0-1.552 1.893c.558-.092 1.13-.14 1.712-.14z" fill="#007ACC" fill-rule="nonzero"/></svg> <div class="quote__text"> By taking the reins into our own hands, we can respond more quickly to new scientific discoveries </div> <img class="quote__img quote__img--no-crop" src="https://wmimages.uzleuven.be/styles/1d41396c1273794b4b4f4759cfde2dfc2f9128dd/2024-10/paul_herijgers.jpg?style=W3sianBlZyI6eyJxdWFsaXR5Ijo3NX19LHsicmVzaXplIjp7ImZpdCI6ImNvdmVyIiwid2lkdGgiOjI0MCwiaGVpZ2h0IjoyNDAsImdyYXZpdHkiOiJjZW50ZXIiLCJ3aXRob3V0RW5sYXJnZW1lbnQiOnRydWV9fV0=&sign=79eeebf044ad223f95e7300213418bbf534adde84ee873df30aa6f948d18535f" /> <div class="quote__source">prof. dr. Paul Herijgers</div> </div> </blockquote> <div id="567bb2e0-c4da-47f0-9069-2893555baaa1" class="block--text text"> <p><strong>Prof. dr. Paul Herijgers, CEO at UZ Leuven</strong>: 'UZ Leuven has been a pioneer in the field of rare diseases for years and has extensive expertise in the diagnosis of genetic syndromes. With a new production facility for ATMPs, doctor and researchers can develop customised therapies specific to the patient's genetic profile or disease. This opens the door to personalised treatments that are more effective and tailored to individual patients. By taking the reins into our own hands, we can respond more quickly to new scientific discoveries and take our clinical research to the next level.'</p> </div> <h2 class="heading-2" id="related">Related</h2> <div class="message is-accent is-link" href="/en/news/first-results-gene-therapy-frontotemporal-degeneration-are-promising"> <div class="message__content"> <div class="message__meta meta">More about "Rare diseases"</div> <h3 class="message__title heading-3">First results gene therapy for frontotemporal degeneration are promising</h3> <div class="messsage__date meta">14 May 2024</div> <div class="message__text">UZ Leuven has been collaborating on an internationl clinical study on gene replacement in FTD with progranulin mutation. </div> <a class="link-btn" href="/en/news/first-results-gene-therapy-frontotemporal-degeneration-are-promising" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div class="message is-accent is-link" href="/en/news/new-biomarker-predicts-success-immunotherapy-kidney-cancer"> <div class="message__content"> <div class="message__meta meta">More about "Rare diseases"</div> <h3 class="message__title heading-3">New biomarker predicts success of immunotherapy in kidney cancer</h3> <div class="messsage__date meta">21 May 2024</div> <div class="message__text">Immunotherapy increases survival rates in kidney cancer, but does not work for everyone. A Leuven research team developed a new method to predict which patients will benefit from it. Their study, published in the journal Nature Medicine, also opens new avenues to even more effective treatments.</div> <a class="link-btn" href="/en/news/new-biomarker-predicts-success-immunotherapy-kidney-cancer" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div class="message is-accent is-link" href="/en/news/leuven-surgeons-transplant-four-organs-during-one-procedure-toddler"> <div class="message__content"> <div class="message__meta meta">More about "Rare diseases"</div> <h3 class="message__title heading-3">Leuven surgeons transplant four organs during one procedure in a toddler</h3> <div class="messsage__date meta">20 December 2023</div> <div class="message__text">A team of UZ Leuven doctors has recently replaced all abdominal organs in a toddler for the first time in Belgium: stomach, liver, pancreas as well as the small intestine were transplanted in one procedure. The young patient was successfully operated on and is doing well. </div> <a class="link-btn" href="/en/news/leuven-surgeons-transplant-four-organs-during-one-procedure-toddler" target="" rel=""> <svg class="link-btn__icon icon is-ghost is-small" width="18" height="18"><use xlink:href="#arrow-right"></use></svg> <span class="link-btn__text"><span class="link-btn__text__content">More info</span></span> </a> </div> </div> <div id="feedback" data-i18n="{"formSource":"node:0cfb713c-c16c-49e7-b418-c751a7a819c1","done":"Thanks for your feedback.","title":"Remarks about this page?","button_yes":"Let us know","email_label":"Email","feedback_label":"Feedback","submit_label":"Submit feedback","error_messages":{"required":"This field is required.","email":"Invalid email.","min_char":"At least 20 characters are required."},"description":"For personal medical enquiries, you have to make an appointment with a physician."}"></div> <div class="meta"> Last edit: 18 October 2024 </div> </div> </article> </div> </main> <footer> <div class="footer"> <div class="footer__row"> <div class="footer__inside"> <div class="footer__columns"> <div class="footer__column"> <h4 class="footer__heading heading-3">Contact</h4> <p><a href="tel:+3216332211" target="_blank" rel="noreferrer noopener">+32 16 33 22 11</a></p> <p>Herestraat 49, 3000 Leuven, Belgium</p> <p><a href="/en/node/13495">All contact information</a></p> <div class="social-list"> <span class="social-list__title">Also find us on:</span> <ul class="list horizontal-list is-small"> <li> <a class="footer__social icon--facebook" href="https://www.facebook.com/uzleuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#facebook"></use></svg> <span class="visually-hidden">Facebook</span> </a> </li> <li> <a class="footer__social icon--twitter" href="https://twitter.com/uzleuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#twitter"></use></svg> <span class="visually-hidden">Twitter</span> </a> </li> <li> <a class="footer__social icon--linkedin" href="https://www.linkedin.com/company/uz-leuven" target="_blank" rel="noopener noreferrer"> <svg width="24" height="24"><use xlink:href="#linkedin"></use></svg> <span class="visually-hidden">LinkedIn</span> </a> </li> </ul> </div> </div> <div class="footer__column"> <h4 class="footer__heading heading-3"> <a class="heading-link" href="/en/consultation-and-admission"><span class="heading-link__text">Consultation and admission</span></a> </h4> <ul class="list"> <li> <a href="/en/consultation-and-admission/consultation-and-function-tests">Consultation</a> </li> <li> <a href="/en/consultation-and-admission/admission">Admission</a> </li> <li> <a href="/en/visits">Visiting hours</a> </li> <li> <a href="/en/greeting-card">Send a greeting card</a> </li> </ul> </div> <div class="footer__column"> <h4 class="footer__heading heading-3"> <a class="heading-link" href="/en/about-us"><span class="heading-link__text">About UZ Leuven</span></a> </h4> <ul class="list"> <li> <a href="/en/news-and-calendar">News and publications</a> </li> <li> <a href="/en/press-and-media">For press and media</a> </li> </ul> </div> </div> </div> </div> <div class="footer__row"> <div class="footer__inside"> <div class="footer__logos footer__columns"></div> </div> </div> </div> <div class="closure"> <div class="closure__inside"> <div class="closure__content"> <ul class="list horizontal-list is-nav closure__links" id="closure"> <li class="closure__item"><a class="closure__link" href="/en/cookie-policy">Cookie policy</a></li> <li class="closure__item"><a class="closure__link" href="/en/privacy-and-your-patient-record">Privacy</a></li> </ul> </div> <div class="closure__wieni"> <a class="wieni" href="https://www.wieni.be" target="_blank" title="site by wieni" rel="noopener noreferrer"> <svg class="wieni__logo" width="61" height="22"><use xlink:href="#wieni"></use></svg> </a> </div> </div> </div> </footer> </div> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"en\/","currentPath":"node\/21683","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"wmcustom_urls":{"search":"\/en\/search"},"analytics":{"nodeType":"Nieuws","isMedischeDienst":0},"outdatedBrowser":{"title":"Your browser is out-of-date","message":"\u003Cp\u003EIt seems you\u0027re using an outdated version of browser-name. 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