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October 2011 | PLOS Medicine

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<div class="txt"><a xmlns:plos="http://plos.org" id="abstract1.p1" name="abstract1.p1" class="link-target"></a><p xmlns:plos="http://plos.org">In the October <a href="http://dx.doi.org/10.1371/journal.pmed.1001113">editorial</a>, the <em>PLoS Medicine</em> Editors reflect on recent research and analysis in <em>PLoS Medicine</em> that highlights the need to fully evaluate rapid and convenient diagnostics. They argue that while rapidly determining the cause of an illness is important, speed and convenience alone are not enough to significantly change health outcomes. In a research article published earlier in the month, <a href="http://dx.doi.org/10.1371/journal.pmed.1001102">Augustine Choko and colleagues</a> assess the uptake and accuracy of home-based supervised oral HIV self-testing in Malawi, demonstrating the feasibility of this approach in a high-prevalence, low-income environment. Their findings indicate that there is strong community readiness to adopt self-testing alongside other HIV counseling and testing strategies in high HIV prevalence settings in urban Africa. <a href="http://dx.doi.org/10.1371/journal.pmed.1001101">Rochelle Walensky and Ingrid Bassett</a> suggest in an accompanying Perspective article that linkage to care must be demonstrated before the success of oral HIV self-testing can be determined, commenting that “beyond making care accessible, the next phase of self-testing feasibility studies must evaluate the completion of the care cascade from testing to treatment to demonstrate true self-testing success.” </p> <a xmlns:plos="http://plos.org" id="abstract1.p2" name="abstract1.p2" class="link-target"></a><p xmlns:plos="http://plos.org"><em>Image Credit: rabanito at <a href="http://www.flickr.com/photos/rabanito/4829687041/">flickr.com</a></em></p> </div> </div> </div> <div class="section"> <a id="Editorial" name="Editorial" toc="Editorial" title="Editorial"></a> <h2 class="item-title lead-in">Editorial</h2> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001113" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Speed and Convenience Aren't Everything with Diagnostics </a> </h3> <p class="authors"> The PLoS Medicine Editors </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 25, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001113">https://doi.org/10.1371/journal.pmed.1001113</a> </p> <h4 class="item-title">Related Articles</h4> <ol class="related"> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.1001063" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Is Scale-Up Worth It? Challenges in Economic Analysis of Diagnostic Tests for Tuberculosis </a> </li> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.1001101" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>HIV Self-testing and the Missing Linkage </a> </li> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.0040202" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Commercial Serological Antibody Detection Tests for the Diagnosis of Pulmonary Tuberculosis: A Systematic Review </a> </li> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.1001102" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>The Uptake and Accuracy of Oral Kits for HIV Self-Testing in High HIV Prevalence Setting: A Cross-Sectional Feasibility Study in Blantyre, Malawi </a> </li> </ol> </div> </div> <div class="section"> <a id="Essay" name="Essay" toc="Essay" title="Essay"></a> <h2 class="item-title lead-in">Essay</h2> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001100" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Do Health and Forensic DNA Databases Increase Racial Disparities? </a> </h3> <p class="authors"> Peter A. Chow-White, Troy Duster </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 4, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001100">https://doi.org/10.1371/journal.pmed.1001100</a> </p> </div> </div> <div class="section"> <a id="Perspective" name="Perspective" toc="Perspective" title="Perspective"></a> <h2 class="item-title lead-in">Perspective</h2> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001101" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>HIV Self-testing and the Missing Linkage </a> </h3> <p class="authors"> Rochelle P. Walensky, Ingrid V. Bassett </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 4, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001101">https://doi.org/10.1371/journal.pmed.1001101</a> </p> <h4 class="item-title">Related Articles</h4> <ol class="related"> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.1001113" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Speed and Convenience Aren't Everything with Diagnostics </a> </li> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.1001102" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>The Uptake and Accuracy of Oral Kits for HIV Self-Testing in High HIV Prevalence Setting: A Cross-Sectional Feasibility Study in Blantyre, Malawi </a> </li> </ol> </div> </div> <div class="section"> <a id="Policy_Forum" name="Policy_Forum" toc="Policy Forum" title="Policy Forum"></a> <h2 class="item-title lead-in">Policy Forums</h2> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001105" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Closing the Policy-Practice Gap in the Management of Child Contacts of Tuberculosis Cases in Developing Countries </a> </h3> <p class="authors"> Philip C. Hill, Merrin E. Rutherford, Rick Audas, Reinout van Crevel, Stephen M. Graham </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 11, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001105">https://doi.org/10.1371/journal.pmed.1001105</a> </p> </div> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001108" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Educating a New Generation of Doctors to Improve the Health of Populations in Low- and Middle-Income Countries </a> </h3> <p class="authors"> Francesca Celletti, Teri A. Reynolds, Anna Wright, Aaron Stoertz, Manuel Dayrit </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 18, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001108">https://doi.org/10.1371/journal.pmed.1001108</a> </p> </div> </div> <div class="section"> <a id="Guidelines_and_Guidance" name="Guidelines_and_Guidance" toc="Guidelines and Guidance" title="Guidelines and Guidance"></a> <h2 class="item-title lead-in">Guidelines and Guidance</h2> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001117" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>STrengthening the Reporting of OBservational studies in Epidemiology – Molecular Epidemiology (STROBE-ME): An Extension of the STROBE Statement </a> </h3> <p class="authors"> Valentina Gallo, Matthias Egger, Valerie McCormack, Peter B. Farmer, John P. A. Ioannidis, Micheline Kirsch-Volders, Giuseppe Matullo, David H. Phillips, Bernadette Schoket, Ulf Stromberg, Roel Vermeulen, Christopher Wild, Miquel Porta, Paolo Vineis </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 25, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001117">https://doi.org/10.1371/journal.pmed.1001117</a> </p> </div> </div> <div class="section"> <a id="Research_Article" name="Research_Article" toc="Research Article" title="Research Article"></a> <h2 class="item-title lead-in">Research Articles</h2> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001102" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>The Uptake and Accuracy of Oral Kits for HIV Self-Testing in High HIV Prevalence Setting: A Cross-Sectional Feasibility Study in Blantyre, Malawi </a> </h3> <p class="authors"> Augustine Talumba Choko, Nicola Desmond, Emily L. Webb, Kondwani Chavula, Sue Napierala-Mavedzenge, Charlotte A. Gaydos, Simon D. Makombe, Treza Chunda, S. Bertel Squire, Neil French, Victor Mwapasa, Elizabeth L. Corbett </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 4, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001102">https://doi.org/10.1371/journal.pmed.1001102</a> </p> <p class="links"> </p> <h4 class="item-title">Related Articles</h4> <ol class="related"> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.1001101" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>HIV Self-testing and the Missing Linkage </a> </li> <li class="related-article"> <a href="https://dx.plos.org/10.1371/journal.pmed.1001113" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Speed and Convenience Aren't Everything with Diagnostics </a> </li> </ol> </div> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001111" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Universal Definition of Loss to Follow-Up in HIV Treatment Programs: A Statistical Analysis of 111 Facilities in Africa, Asia, and Latin America </a> </h3> <p class="authors"> Benjamin H. Chi, Constantin T. Yiannoutsos, Andrew O. Westfall, Jamie E. Newman, Jialun Zhou, Carina Cesar, Martin W. G. Brinkhof, Albert Mwango, Eric Balestre, Gabriela Carriquiry, Thira Sirisanthana, Henri Mukumbi, Jeffrey N. Martin, Anna Grimsrud, Melanie Bacon, Rodolphe Thiebaut, on behalf of the International Epidemiologic Databases to Evaluate AIDS Collaboration </p> <p class="article-info"><i>PLOS Medicine</i>: <span class="article-info--date">published October 25, 2011</span> <span class="separator">|</span> <a href="https://doi.org/10.1371/journal.pmed.1001111">https://doi.org/10.1371/journal.pmed.1001111</a> </p> <p class="links"> </p> </div> <div class="item cf"> <h3 class="item--article-title"> <a href="/plosmedicine/article?id=10.1371/journal.pmed.1001103" title="Read Open Access Article"> <?xml version="1.0" encoding="UTF-8"?>Estimating Infection Attack Rates and Severity in Real Time during an Influenza Pandemic: Analysis of Serial Cross-Sectional Serologic Surveillance Data </a> </h3> <p class="authors"> Joseph T. Wu, Andrew Ho, Edward S. K. Ma, Cheuk Kwong Lee, Daniel K. W. Chu, Po-Lai Ho, Ivan F. N. Hung, Lai Ming Ho, Che Kit Lin, Thomas Tsang, Su-Vui Lo, Yu-Lung Lau, Gabriel M. 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