Search results for: enoxacin

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enoxacin</title> <meta name="description" content="Search results for: enoxacin"> <meta name="keywords" content="enoxacin"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="enoxacin"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 2</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: enoxacin</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Evaluation of in vitro Inhibitory Effect of Enoxacin on Babesia and Theileria Parasites</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mosaab%20A.%20Omar">Mosaab A. Omar</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Saleh%20Al-Aboody"> Mohammad Saleh Al-Aboody</a>, <a href="https://publications.waset.org/abstracts/search?q=Mohmed%20A.%20Rizk"> Mohmed A. Rizk</a>, <a href="https://publications.waset.org/abstracts/search?q=Shimaa%20M.%20Elsayed"> Shimaa M. Elsayed</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20ElSify"> Ahmed ElSify</a>, <a href="https://publications.waset.org/abstracts/search?q=Naoaki%20Yokoyama"> Naoaki Yokoyama</a>, <a href="https://publications.waset.org/abstracts/search?q=Ikuo%20Igarashi"> Ikuo Igarashi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Enoxacin is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid used mainly in the treatment of urinary tract infections and gonorrhea. Also, it has been shown recently that it may have cancer inhibiting effect. The primary antibabesial effect of Enoxacin is due to inhibition of DNA gyrase subunit A, and DNA topoisomerase. In the present study, enoxacin was tested as a potent inhibitor against the in vitro growth of bovine and equine Piroplasms. The in vitro growth of five Babesia species that were tested was significantly inhibited (P<0.05) by micromolar concentrations of enoxacin (IC50 values= 13.5, 7.2, 7.5, and 24.2 碌M for Babesia bovis, Babesia bigemina, Babesia caballi, and Theileria equi, respectively). Enoxacin IC50 values for Babesia and Theileria parasites were satisfactory as the drug is a potent antibacterial drug with minimum side effects. Therefore, enoxacin might be used for the treatment of Babesiosis and Theileriosis especially in case of mixed infections with bacterial diseases or in the case of animal sensitivity against diminazin toxicity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=enoxacin" title="enoxacin">enoxacin</a>, <a href="https://publications.waset.org/abstracts/search?q=Babesia" title=" Babesia"> Babesia</a>, <a href="https://publications.waset.org/abstracts/search?q=Theileria" title=" Theileria"> Theileria</a>, <a href="https://publications.waset.org/abstracts/search?q=IC50%20and%20dimenazin" title=" IC50 and dimenazin"> IC50 and dimenazin</a> </p> <a href="https://publications.waset.org/abstracts/24342/evaluation-of-in-vitro-inhibitory-effect-of-enoxacin-on-babesia-and-theileria-parasites" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/24342.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">468</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Non-Steroidal Anti-inflammatory Drugs, Plant Extracts, and Characterized Microparticles to Modulate Antimicrobial Resistance of Epidemic Meca Positive S. Aureus of Dairy Origin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amjad%20I.%20Aqib">Amjad I. Aqib</a>, <a href="https://publications.waset.org/abstracts/search?q=Shanza%20R.%20Khan"> Shanza R. Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Tanveer%20Ahmad"> Tanveer Ahmad</a>, <a href="https://publications.waset.org/abstracts/search?q=Syed%20A.%20R.%20Shah"> Syed A. R. Shah</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20A.%20Naseer"> Muhammad A. Naseer</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Shoaib"> Muhammad Shoaib</a>, <a href="https://publications.waset.org/abstracts/search?q=Iqra%20Sarwar"> Iqra Sarwar</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20F.%20A.%20Kulyar"> Muhammad F. A. Kulyar</a>, <a href="https://publications.waset.org/abstracts/search?q=Zeeshan%20A.%20Bhutta"> Zeeshan A. Bhutta</a>, <a href="https://publications.waset.org/abstracts/search?q=Mumtaz%20A.%20Khan"> Mumtaz A. Khan</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahboob%20Ali"> Mahboob Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Khadija%20Yasmeen"> Khadija Yasmeen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The current study focused on resistance modulation of dairy linked epidemic mec A positive S. aureus for resistance modulation by plant extract (Eucalyptus globolus, Calotropis procera), NSAIDs, and star like microparticles. Zinc oxide {ZnO}c and {Zn (OH)鈧倉 microparticles were synthesized by solvothermal method and characterized by calcination, X-ray diffraction (XRD), and scanning electron microscope (SEM). Plant extracts were prepared by the Soxhlet extraction method. The study found 34% of subclinical samples (n=200) positive for S. aureus from dairy milk having significant (p < 0.05) association of assumed risk factors with pathogen. The antimicrobial assay showed 55, 42, 41, and 41% of S. aureus resistant to oxacillin, ciprofloxacin, streptomycin, and enoxacin. Amoxicillin showed the highest percentage of increase in zone of inhibitions (ZOI) at 100mg of Calotropis procera extract (31.29%) followed by 1mg/mL (28.91%) and 10mg/mL (21.68%) of Eucalyptus globolus. Amoxicillin increased ZOI by 42.85, 37.32, 29.05, and 22.78% in combination with 500 ug/ml with each of diclofenac, aspirin, ibuprofen, and meloxicam, respectively. Fractional inhibitory concentration indices (FICIs) showed synergism of amoxicillin with diclofenac and aspirin and indifferent synergy with ibuprofen and meloxicam. The preliminary in vitro finding of combination of microparticles with amoxicillin proved to be synergistic, giving rise to 26.74% and 14.85% increase in ZOI of amoxicillin in combination with zinc oxide and zinc hydroxide, respectively. The modulated antimicrobial resistance incurred by NSAIDs, plant extracts, and microparticles against pathogenic S. aureus invite immediate attention to probe alternative antimicrobial sources. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20resistance" title="antimicrobial resistance">antimicrobial resistance</a>, <a href="https://publications.waset.org/abstracts/search?q=dairy%20milk" title=" dairy milk"> dairy milk</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles"> nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=NSIDs" title=" NSIDs"> NSIDs</a>, <a href="https://publications.waset.org/abstracts/search?q=plant%20extracts" title=" plant extracts"> plant extracts</a>, <a href="https://publications.waset.org/abstracts/search?q=resistance%20modulation" title=" resistance modulation"> resistance modulation</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20aureus" title=" S. aureus"> S. aureus</a> </p> <a href="https://publications.waset.org/abstracts/129936/non-steroidal-anti-inflammatory-drugs-plant-extracts-and-characterized-microparticles-to-modulate-antimicrobial-resistance-of-epidemic-meca-positive-s-aureus-of-dairy-origin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/129936.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">212</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a 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Search results for: enoxacin