平均降价63%，预计明年减负超500亿！最新国家医保目录出炉，新增多款抗癌新药_药品_创新

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18:21</span> <span data-role="original-link"> 来源: <a href="https://translate.google.com/website?sl=auto&tl=en&hl=en-GB&u=https://www.time-weekly.com/post/316474" target="_blank">时代周报</a></span> <div id="abroad-share-box" class="abroad-share-box"><share /> </div> <div class="area"> <span>发布于：</span><span>广东省</span> </div> </div> </div> <article class="article" id="mp-editor"> <p><img src="https://q9.itc.cn/q_70/images03/20241128/b4ff12e5ab234a66b67204b338b61faf.jpeg" width="33%"></p> <p><span>图片来源：图虫创意</span></p> <p>11月28日上午，国家医保局召开新闻发布会，介绍2024年国家医保药品目录调整工作，并公布新版药品目录。</p> <p>根据会上介绍，在今年的调整中，有91种药品新增进入国家医保药品目录，肿瘤、慢性病和罕见病用药仍然是本次医保目录调整关注的重点。在所有新增的药品中，包括肿瘤用药26个（含4个罕见病）、糖尿病等慢性病用药15个（含2个罕见病）、罕见病用药13个等。</p> <p>在谈判/竞价环节，共有117个目录外药品参加，其中89个谈判/竞价成功，成功率为76%，平均降价63%，成功率和价格降幅与2023年基本相当。叠加谈判降价和医保报销，预计2025年将为患者减负超500亿元。</p> <p>国家医保局方面表示，总体上，经过国家医保局成立以来连续7年目录调整，程序规则更加完善，评审测算更加透明，落地要求更加全面具体，企业对药品价格的预期更加客观理性，患者受益水平稳步提升，同时也有效提振了医药行业加大研发创新的信心，有利于促进经济社会发展，调整结果符合预期。</p> <p>鼓励创新是今年医保目录调整的一大特点。</p> <p>据统计，在新增的91种药品中，有90个为5年内新上市品种，其中有38个药品是“全球新”的创新药，无论是比例还是绝对数量都创历年新高。在谈判阶段，创新药的谈判成功率超过90%，较总体成功率高16个百分点。</p> <p>新闻发布会后，家医药企业也发布了医保谈判“战报”。根据企业公告，新版医保目录纳入了款重磅创新药。</p> <p>被称为“最强ADC双抗”的德曲妥珠单抗（商品名：优赫得）成功通过今年的医保谈判，进入医保目录。该款药物由第一三共、阿斯利康共同开发，于2023年2月首次在中国获批上市，但在去年的医保谈判中，德曲妥珠单抗并未通过。根据第一三共财报，德曲妥珠单抗自上市以来销售业绩快速增长，2023年全球销售额超25亿美元，预计2024年将突破30亿美元销售大关。</p> <p>新增的双抗新药还有康方生物（09926.HK）独立自主研发的全球首创新药，分别为卡度尼利单抗注射液（PD-1/CTLA-4双抗，商品名：开坦尼）和依沃西单抗注射液（PD-1/VEGF双抗，商品名：依达方）。对于该谈判结果，康方生物方面表示符合预期。</p> <div class="lookall-box"> <div class="lookall-shadow"></div> <section class="lookall"><a href="javascript:;?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=en-GB" class="show-all" id="showMore"> <em>展开全文</em> </a> </section> </div> <div class="hidden-content control-hide"> <p>“我们非常欣喜地看到卡度尼利和依沃西均成功被纳入国家医保目录，这体现了国家对卡度尼利和依沃西创新价值和临床价值的高度认可，也体现了国家对中国创新药物发展的支持和培育，进一步坚定了康方生物走源头创新发展道路的信心。”康方生物创始人、董事长、总裁兼首席执行官夏瑜表示。</p> <p>据康方生物2024年中报，卡度尼利实现收入7.1亿元，同比增长16.5%。依沃西于今年5月24日获批上市，在约一个月的销售时间内，依沃西实现了1.03亿元的收入。此外，依沃西还在一项关于NSCLC（非小细胞肺癌）的“头对头”试验中，击败了来自默沙东的帕博利珠单抗（商品名：Keytruda/可瑞达，俗称“K药”），引起了行业关注。</p> <p>2024年国家医保药品目录调整药物经济学专家组组长陈文在新闻发布会上表示，医保局建立了以患者健康获益为核心的维价值评估体系，旨在引导医药行业瞄准真正的创新，努力创造更高的临床价值。对于创新程度高、患者获益大的药品，专家组在测算时会给予较高的经济性阈值。</p> <p>上海市卫生和健康发展研究中心主任金春林对时代财经表示：“‘真创新，真获益’主要体现在该药物与对照药物相比，其OS值（即生存时间）是否有所延长，PFS值（即无进展生存期）是否有所提升，以及它的临床疗效是否有所提高。同时还需要考虑它的安全性，即副作用是否有所减轻，以及病人的便利程度，给药频次是否可以降低等。这些方面，包括病人的获益、疗效，以及药品新靶点的发现、新结构的发现，都可以被视为真正的创新和获益。”</p> <p>此外，针对部分医保目录药品进院难的问题，国家医保局相关负责人也明确指出：“目录调整只是第一步，目录的落地才是老百姓真正能够享受到目录调整红利的最后一公里，这决定着医保目录调整的成效。”</p> <p>在此次医保目录调整的通知中，国家医保局特别强调了关于药品的配备使用、推广推荐、管理监督等方面的一些要求，以确保目录能够真正的落地见效，更好地满足患者的合理用药需求。医保局方面要求，各定点医疗机构原则上要于明年的2月底之前召开药事会，根据新版的医保药品目录情况，及时调整本机构的用药目录，保障临床的诊疗需求和患者的合理用药权益。定点医疗机构不得以医保总额限制、医疗机构用药目录数量、药占比为由影响药品进院。</p> <p>本网站上的内容（包括但不限于文字、图片及音视频），除转载外，均为时代在线版权所有，未经书面协议授权，禁止转载、链接、转贴或以其他方式使用。违反上述声明者，本网将追究其相关法律责任。如其他媒体、网站或个人转载使用，请联系本网站丁先生：news@time-weekly.com<a 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