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data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-214.png'> <div class="row"> <div class="columns small-12"> <div class="h1"> <h1>Cytokines for immune cell therapy manufacturing</h1> <h3><span style="color: #31c8d8;">Animal-free RUO and GMP Liquid and Lyophilized</span></h3> </div> </div> </div> </div> <div class="row"> <div class="columns small-12"> <div class="sr-main-content"> <div class="wpb-content-wrapper"><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-227.png'> <div class="corner-image bottom-right"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/figure-cell-4.png" alt="figure-cell-4"> </div> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/500x500-STP-Cytokines-3.png" alt="500×500 STP Cytokines 3"> </div> </div> </div> <div class="columns small-12 medium-6 content color-white "> <h2 class="title color-navy-blue mb-40">Animal-Free Cytokines that scale smartly.</h2> <div class="text last-no-margin"><p>We source Bio-Techne animal-free RUO and GMP-grade IL-2, IL-7, IL-15, and IL-21 liquid and lyophilized cytokines because they have the consistency, flexibility, quality, and regulatory support to facilitate the seamless scale-up of immune cell therapy manufacturing.</p> <p>Focusing on cytokines for T cell and NK cell expansion, our GMP-grade cytokines boast robust reproducible bioactivity and flexible packaging formats that will accommodate closed-system requirements as you progress through clinical trials.</p> <p><a href="https://live-scaleready.pantheonsite.io/products/reagents-and-media/liquid-cytokines-2/" target="_blank" rel="noopener">Learn more about Liquid Cytokines</a></p> </div> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-239.png'> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 small-order-1 medium-order-2 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <a href="https://www.scaleready.com/resource/il-2-il-7-and-il-15-cytokines-brochure/" target="_blank"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/GMp.jpg" alt="GMP recombinant human animal-free proteins"> </a> </div> </div> </div> <div class="columns small-12 medium-6 content color-black small-order-2 medium-order-1"> <h2 class="title color-navy-blue mb-40">Animal-free cytokines, guaranteed.</h2> <div class="text last-no-margin"><p>With ScaleReady, you’ll never need to worry if your RUO or GMP cytokines are truly animal-free. With industry-leading <em>e. coli</em>-derived animal-free recombinant protein manufacturing, our proteins minimize process risk by eliminating animal contaminants and mammalian pathogens.</p> <p>Animal-free certificates of origin are available, and traceable batch records are kept for all our recombinant human RUO and GMP cytokines.</p> </div> <a class="button mb-0" href="https://www.scaleready.com/resource/il-2-il-7-and-il-15-cytokines-brochure/" target="_blank"> Download the Brochure </a> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-269.png'> <div class="corner-image bottom-left"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/figure-molecule.png" alt="figure-molecule"> </div> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <a href="https://www.scaleready.com/product/gmp-cytokines-for-cell-therapy-manufacturing/#cytokine-inquiry-form" target=""> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/Web-image-1400x1400-7.jpg" alt="GMP cytokine master cell lot control comparison"> </a> </div> </div> </div> <div class="columns small-12 medium-6 content color-white "> <h2 class="title color-navy-blue mb-40">Cytokines with high bioactivity and low variability.</h2> <div class="text last-no-margin"><p>Smart sourcing of raw materials is necessary when building a commercially viable cell therapy manufacturing process. With high bioactivity and low lot-to-lot variability, Bio-Techne’s animal-free RUO and GMP cytokines can speed up your process development, lower manufacturing risk, and work favorably toward lowering overall manufacturing costs.</p> </div> <a class="button mb-0" href="https://www.scaleready.com/product/gmp-cytokines-for-cell-therapy-manufacturing/#cytokine-inquiry-form" target=""> Test Free Samples </a> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div data-vc-full-width="true" data-vc-full-width-init="false" class="vc_row wpb_row vc_row-fluid ptb-80 pb-50 vc_custom_1697535620093 vc_row-has-fill"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <h3 style="text-align: center;">Stability of Cytokines in Media at different temperatures</h3> </div> </div> <div class="vc_row wpb_row vc_inner vc_row-fluid row small-up-1 medium-up-3"><div class="columns mb-35 wpb_column vc_column_container vc_col-sm-4"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_single_image wpb_content_element vc_align_left wpb_content_element"> <figure class="wpb_wrapper vc_figure"> <div class="vc_single_image-wrapper vc_box_border_grey"><img fetchpriority="high" decoding="async" width="903" height="687" src="https://www.scaleready.com/wp-content/uploads/2023/11/Stability-of-Cytokines-in-Media-01.png" class="vc_single_image-img attachment-full" alt="cytokine stability in media" title="Stability of Cytokines in Media-01" /></div> </figure> </div> </div></div></div><div class="columns mb-35 wpb_column vc_column_container vc_col-sm-4"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_single_image wpb_content_element vc_align_left wpb_content_element"> <figure class="wpb_wrapper vc_figure"> <div class="vc_single_image-wrapper vc_box_border_grey"><img decoding="async" width="903" height="687" src="https://www.scaleready.com/wp-content/uploads/2023/11/Stability-of-Cytokines-in-Media-03.png" class="vc_single_image-img attachment-full" alt="Stability of Cytokines in Media-03" title="Stability of Cytokines in Media-03" /></div> </figure> </div> </div></div></div><div class="columns mb-35 wpb_column vc_column_container vc_col-sm-4"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_single_image wpb_content_element vc_align_left wpb_content_element"> <figure class="wpb_wrapper vc_figure"> <div class="vc_single_image-wrapper vc_box_border_grey"><img decoding="async" width="904" height="687" src="https://www.scaleready.com/wp-content/uploads/2023/11/Stability-of-Cytokines-in-Media-04.png" class="vc_single_image-img attachment-full" alt="Stability of Cytokines in Media-04" title="Stability of Cytokines in Media-04" /></div> </figure> </div> </div></div></div></div><div class="vc_row wpb_row vc_inner vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="wpb_text_column wpb_content_element" > <div class="wpb_wrapper"> <p>*IL-2 was used at 200IU/mL, which translates to 17860pg/mL</p> </div> </div> </div></div></div></div></div></div></div></div><div class="vc_row-full-width vc_clearfix"></div><div class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" data-src='https://www.scaleready.com/wp-content/uploads/2021/09/Group-239.png'> <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/GMP-Facility-Bio-Techne-1.jpg" alt="Bio-Techne GMP cytokine animal-free manufacturing facility"> </div> </div> </div> <div class="columns small-12 medium-6 content color-black "> <h2 class="title color-navy-blue mb-40">Consistent quality that scales through clinical trials.</h2> <div class="text last-no-margin"><p>The <a href="https://live-scaleready.pantheonsite.io/scaleready-platform/quality/" target="_blank" rel="noopener">quality of Bio-Techne cytokines</a> is unmatched. Rigorous master cell lot control and lot-to-lot bioactivity testing, uniquely elevates the performance and consistency of our GMP cytokines to meet the long-term manufacturing requirements of the cell therapy industry.</p> <p>Paired with Bio-Techne’s<a href="https://www.youtube.com/watch?v=H6w_32k51RQ"> new large scale animal-free GMP manufacturing facility</a>, the ScaleReady platform is prepared to provide a steady supply of cytokines throughout scale up and out of your cell therapy.</p> </div> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> </div></div></div></div><div id="cytokine-product-list" class="vc_row wpb_row vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"><div class="sr_full_width_content bg-cover st-lazy-load-bg ptb-80 " > <div class="row align-center"> <div class="columns small-12 medium-12 large-10"> <h2 class="title color-navy-blue mb-20 smb-15 text-center">Animal-Free RUO and GMP Proteins for T and NK Cell Therapy</h2> <div class="paragraph-last-no-margin text-center mb-40"> Scaling up from research to clinical can present many challenges, <strong>but your confidence in cytokine performance shouldn’t be one of them.</strong> Your program needs supply chain security, and assurance of consistent RUO to GMP bioactivity all while moving with speed and efficiency… and to do so <em>shouldn’t have any compromise</em>. </div> <div class="row align-justify mb-30 smb-0"> <div class="columns medium-4 small-12 flex-container align-center smb-35 mb-25 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="color-white card-news big full-height flex-container flex-dir-column su"> <div class="mb-25 matchHeight"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/500x500-STP-Cytokines-IL-2.png" alt="500×500 STP Cytokines IL-2"> </div> <div class="text-center color-navy-blue ff-barlow fw-500 mb-20">rhIL-2 Proteins</div> <div> <a class="button small mb-0 expanded" href="https://www.scaleready.com/products/recombinant-human-il-2-protein-gmp-animal-free/" > LEARN MORE </a> </div> </div> </div> <div class="columns medium-4 small-12 flex-container align-center smb-35 mb-25 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="color-white card-news big full-height flex-container flex-dir-column su"> <div class="mb-25 matchHeight"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/500x500-STP-Cytokines-IL-7-15.png" alt="500×500 STP Cytokines IL-7 15"> </div> <div class="text-center color-navy-blue ff-barlow fw-500 mb-20">rhIL-7 & rhIL-15 Proteins</div> <div> <a class="button small mb-0 expanded" href="https://www.scaleready.com/products/recombinant-human-il-7-il-15-protein-animal-free/" > LEARN MORE </a> </div> </div> </div> <div class="columns medium-4 small-12 flex-container align-center smb-35 mb-25 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="color-white card-news big full-height flex-container flex-dir-column su"> <div class="mb-25 matchHeight"> <img decoding="async" src="https://www.scaleready.com/wp-content/uploads/2021/09/500x500-STP-Cytokines-IL-21.png" alt="500×500 STP Cytokines IL-21"> </div> <div class="text-center color-navy-blue ff-barlow fw-500 mb-20">rhIL-21 Proteins</div> <div> <a class="button small mb-0 expanded" href="" > LEARN MORE </a> </div> </div> </div> </div> </div> </div> </div> </div></div></div></div><div data-vc-full-width="true" data-vc-full-width-init="false" class="vc_row wpb_row vc_row-fluid bg-cover vc_custom_1697789676138 vc_row-has-fill"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class="sr_full_width_content section-50-wrapper st-lazy-load-bg bg-cover" > <div class="section-50-items position-relative zIndex-4"> <div class="small-collapse-section"> <div class="row align-middle section-50-item "> <div class="columns small-12 medium-6 small-order-1 medium-order-2 "> <div class="position-relative"> <div class="revealator-zoomin rev-item"></div> <div class="img-wrapper zi"> <a href="https://www.scaleready.com/products/reagents-and-media/liquid-cytokines-2/" target="_blank"> <img class="st-lazy-load-bg full-width zi" data-src="https://www.scaleready.com/wp-content/uploads/2021/09/500x500-STP-Cytokines.png" alt="500×500 STP Cytokines"> </a> </div> </div> </div> <div class="columns small-12 medium-6 content color-black small-order-2 medium-order-1"> <h2 class="title color-navy-blue mb-40">Flexible formats to fit your cell therapy manufacturing process.</h2> <div class="text last-no-margin"><p>Now you can define the format of your raw materials. Bio-Techne GMP cytokines are available in off-the-shelf vials and custom mass/vial (liquid or lyophilized). All formats uphold rigorous quality and regulatory standards for GMP ancillary materials.</p> </div> <a class="button mb-0" href="https://www.scaleready.com/products/reagents-and-media/liquid-cytokines-2/" target="_blank"> Learn More About Liquid Cytokines </a> </div> </div> <div class="row"> <div class="columns small-12 medium-12"> </div> </div> <script type="text/javascript"> jQuery('.fifty-fifty-content-calendar').parents('.section-50-wrapper').addClass('zIndex-3'); </script> </div> </div> </div> <div class="wpb_text_column wpb_content_element" id="product_table"> <div class="wpb_wrapper"> <div class="ptb-80 paragraph-last-no-margin"> <h2 class="color-deep-blue h3 small-text-36-42 title mb-40 smb-30">Product Table</h2> <table border="1" width="100%"> <thead> <tr> <th>GMP Protein</th> <th>Source</th> <th>DMF Filed</th> <th>Format</th> <th>Sizes</th> <th>Catalog #</th> <th width="220">Research-grade catalog #</th> </tr> </thead> <tbody> <tr> <td rowspan="5">rhIL-2</td> <td rowspan="5">E. coli</td> <td rowspan="5">Yes</td> <td rowspan="2">Standard vial</td> <td>50 µg <span class="show-when-stack"> , 1 mg</span></td> <td rowspan="3"><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-il-2-gmp-protein-cf_bt-002-gmp" target="_blank" rel="noopener">BT-002-GMP</a></td> <td rowspan="3"><a href="https://www.rndsystems.com/products/recombinant-human-il-2-protein-animal-free_bt-002-afl" target="_blank" rel="noopener">BT-002-AFL</a></td> </tr> <tr class="hide-when-stack"> <td>1 mg</td> </tr> <tr> <td colspan="2">Custom fill*</td> </tr> <tr> <td rowspan="2">Standard Liquid Fill Vial</td> <td>50 µg <span class="show-when-stack">, 1 mg</span></td> <td rowspan="2">BT-002-GMP/LQ</td> <td rowspan="2">BT-002-AFL/LQ</td> </tr> <tr class="hide-when-stack"> <td>1 mg</td> </tr> <tr> <td rowspan="4">rhIL-7</td> <td rowspan="4">E. coli</td> <td rowspan="4">Yes</td> <td rowspan="2">Standard vial</td> <td><span class="hide-when-stack">25 µg</span> <span class="show-when-stack">25 µg, 1 mg</span></td> <td rowspan="3"><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-il-7-gmp-protein-cf_bt-007-gmp" target="_blank" rel="noopener">BT-007-GMP</a></td> <td rowspan="3"><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-il-7-protein-animal-free_bt-007-afl" target="_blank" rel="noopener">BT-007-AFL</a></td> </tr> <tr class="hide-when-stack"> <td>1 mg</td> </tr> <tr> <td colspan="2">Custom fill*</td> </tr> <tr> <td>Standard Liquid Fill Vial</td> <td>25ug</td> <td>BT-007-GMP/LQ</td> <td>BT-007-AFL/LQ</td> </tr> <tr> <td rowspan="4">rhIL-15</td> <td rowspan="4">E. coli</td> <td rowspan="4">Yes</td> <td rowspan="2">Standard vial</td> <td><span class="hide-when-stack">25 µg</span> <span class="show-when-stack">25 µg, 1 mg</span></td> <td rowspan="3"><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-il-15-gmp-protein-cf_bt-015-gmp" target="_blank" rel="noopener">BT-015-GMP</a></td> <td rowspan="3"><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-il-15-protein-animal-free_bt-015-afl" target="_blank" rel="noopener">BT-015-AFL</a></td> </tr> <tr class="hide-when-stack"> <td>1 mg</td> </tr> <tr> <td colspan="2">Custom fill*</td> </tr> <tr> <td>Standard Liquid Fill Vial</td> <td>25ug</td> <td>BT-015-GMP/LQ</td> <td>BT-017-AFL/LQ</td> </tr> <tr> <td rowspan="3">rhIL-21</td> <td rowspan="3">E. coli</td> <td rowspan="3">Yes</td> <td rowspan="2">Standard vial</td> <td><span class="hide-when-stack">25 µg</span> <span class="show-when-stack">25 µg, 1 mg</span></td> <td rowspan="3"><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-il-21-gmp-protein-cf_8879-gmp" target="_blank" rel="noopener">8879-GMP</a></td> <td rowspan="3"><a href="https://www.bio-techne.com/p/proteins-enzymes/recombinant-human-il-21-protein_8879-il" target="_blank" rel="noopener">8879-IL</a></td> </tr> <tr class="hide-when-stack"> <td>1 mg</td> </tr> <tr> <td colspan="2">Custom fill*</td> </tr> </tbody> </table> <p><small>*options to fill by mass, activity, lyophilized, and liquid-frozen</small></p> </div> </div> </div> </div></div></div></div><div class="vc_row-full-width vc_clearfix"></div><div id="cytokine-inquiry-form" data-vc-full-width="true" data-vc-full-width-init="false" class="vc_row wpb_row vc_row-fluid bg-cover ptb-80 padding-bottom-0 vc_custom_1697789886099 vc_row-has-fill"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"><div class="row align-center"> <div class="column small-12 medium-12 large-9 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box mb-50 smb-55 su"> <h3 class="color-deep-blue title small-text-36-42">How to order</h3> <div class="row"> <div class="columns smb-22">Fill out the form below or contact us directly to place an order or consult with a ScaleReady expert.</div> <div class="columns shrink small-full-width"> <div><span class="ff-pnsb color-deep-blue">Phone:</span> 651-628-9259</div> <div><span class="ff-pnsb color-deep-blue">Email:</span> info@scaleready.com</div> <div><span class="ff-pnsb color-deep-blue">Fax:</span> 651-628-9507</div> </div> </div> </div> </div> </div> <div id="cytokine-inquiry-form" class="vc_row wpb_row vc_inner vc_row-fluid"><div class="wpb_column vc_column_container vc_col-sm-12"><div class="vc_column-inner"><div class="wpb_wrapper"> <div class='gf_browser_ie gf_browser_ie7 gform_wrapper gravity-theme gform-theme--no-framework form-align-center_wrapper' data-form-theme='gravity-theme' data-form-index='0' id='gform_wrapper_5' style='display:none'><div id='gf_5' class='gform_anchor' tabindex='-1'></div> <div class='gform_heading'> <h2 class="gform_title">Cytokine Inquiry</h2> </div><form method='post' enctype='multipart/form-data' id='gform_5' class='form-align-center' action='/product/gmp-cytokines-for-cell-therapy-manufacturing/#gf_5' data-formid='5' novalidate> <div class='gform-body gform_body'><div id='gform_fields_5' class='gform_fields top_label form_sublabel_below description_below validation_below'><div id="field_5_1" class="gfield gfield--type-text gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_1" ><label class='gfield_label gform-field-label' for='input_5_1'>*First Name<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_text'><input name='input_1' id='input_5_1' type='text' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_5_2" class="gfield gfield--type-text gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_2" ><label class='gfield_label gform-field-label' for='input_5_2'>*Last Name<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_text'><input name='input_2' id='input_5_2' type='text' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_5_3" class="gfield gfield--type-email gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_3" ><label class='gfield_label gform-field-label' for='input_5_3'>*Email Address<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_email'> <input name='input_3' id='input_5_3' type='email' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_5_5" class="gfield gfield--type-text gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_5" ><label class='gfield_label gform-field-label' for='input_5_5'>*Company<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_text'><input name='input_5' id='input_5_5' type='text' value='' class='large' aria-required="true" aria-invalid="false" /> </div></div><div id="field_5_9" class="gfield gfield--type-select gfield--width-half gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_9" ><label class='gfield_label gform-field-label' for='input_5_9'>Country<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></label><div class='ginput_container ginput_container_select'><select name='input_9' id='input_5_9' class='large gfield_select' aria-required="true" aria-invalid="false" ><option value='Afghanistan' >Afghanistan</option><option value='Albania' >Albania</option><option value='Algeria' >Algeria</option><option value='American Samoa' >American Samoa</option><option value='Andorra' >Andorra</option><option value='Angola' >Angola</option><option value='Anguilla' >Anguilla</option><option value='Antarctica' >Antarctica</option><option value='Antigua and Barbuda' >Antigua and Barbuda</option><option value='Argentina' >Argentina</option><option value='Armenia' >Armenia</option><option value='Aruba' >Aruba</option><option value='Australia' >Australia</option><option value='Austria' >Austria</option><option value='Azerbaijan' >Azerbaijan</option><option value='Bahamas' >Bahamas</option><option value='Bahrain' >Bahrain</option><option value='Bangladesh' >Bangladesh</option><option value='Barbados' >Barbados</option><option value='Belarus' >Belarus</option><option value='Belgium' >Belgium</option><option value='Belize' >Belize</option><option value='Benin' >Benin</option><option value='Bermuda' >Bermuda</option><option value='Bhutan' >Bhutan</option><option value='Bolivia' >Bolivia</option><option value='Bonaire, Sint Eustatius and Saba' >Bonaire, Sint Eustatius and Saba</option><option value='Bosnia and Herzegovina' >Bosnia and Herzegovina</option><option value='Botswana' >Botswana</option><option value='Bouvet Island' >Bouvet Island</option><option value='Brazil' >Brazil</option><option value='British Indian Ocean Territory' >British Indian Ocean Territory</option><option value='Brunei Darussalam' >Brunei Darussalam</option><option value='Bulgaria' >Bulgaria</option><option value='Burkina Faso' >Burkina Faso</option><option value='Burundi' >Burundi</option><option value='Cambodia' >Cambodia</option><option value='Cameroon' >Cameroon</option><option value='Canada' >Canada</option><option value='Cape Verde' >Cape Verde</option><option value='Cayman Islands' >Cayman Islands</option><option value='Central African Republic' >Central African Republic</option><option value='Chad' >Chad</option><option value='Chile' >Chile</option><option value='China' >China</option><option value='Christmas Island' >Christmas Island</option><option value='Cocos Islands' >Cocos Islands</option><option value='Colombia' >Colombia</option><option value='Comoros' >Comoros</option><option value='Congo, Democratic Republic of the' >Congo, Democratic Republic of the</option><option value='Congo, Republic of the' >Congo, Republic of the</option><option value='Cook Islands' >Cook Islands</option><option value='Costa Rica' >Costa Rica</option><option value='Croatia' >Croatia</option><option value='Cuba' >Cuba</option><option value='Curaçao' >Curaçao</option><option value='Cyprus' >Cyprus</option><option value='Czech Republic' >Czech Republic</option><option value='Côte d'Ivoire' >Côte d'Ivoire</option><option value='Denmark' >Denmark</option><option value='Djibouti' >Djibouti</option><option value='Dominica' >Dominica</option><option value='Dominican Republic' >Dominican Republic</option><option value='Ecuador' >Ecuador</option><option value='Egypt' >Egypt</option><option value='El Salvador' >El Salvador</option><option value='Equatorial Guinea' >Equatorial Guinea</option><option value='Eritrea' >Eritrea</option><option value='Estonia' >Estonia</option><option value='Eswatini (Swaziland)' >Eswatini (Swaziland)</option><option value='Ethiopia' >Ethiopia</option><option value='Falkland Islands' >Falkland Islands</option><option value='Faroe Islands' >Faroe Islands</option><option value='Fiji' >Fiji</option><option value='Finland' >Finland</option><option value='France' >France</option><option value='French Guiana' >French Guiana</option><option value='French Polynesia' >French Polynesia</option><option value='French Southern Territories' >French Southern Territories</option><option value='Gabon' >Gabon</option><option value='Gambia' >Gambia</option><option value='Georgia' >Georgia</option><option value='Germany' >Germany</option><option value='Ghana' >Ghana</option><option value='Gibraltar' >Gibraltar</option><option value='Greece' >Greece</option><option value='Greenland' >Greenland</option><option value='Grenada' >Grenada</option><option value='Guadeloupe' >Guadeloupe</option><option value='Guam' >Guam</option><option value='Guatemala' >Guatemala</option><option value='Guernsey' >Guernsey</option><option value='Guinea' >Guinea</option><option value='Guinea-Bissau' >Guinea-Bissau</option><option value='Guyana' >Guyana</option><option value='Haiti' >Haiti</option><option value='Heard and McDonald Islands' >Heard and McDonald Islands</option><option value='Holy See' >Holy See</option><option value='Honduras' >Honduras</option><option value='Hong Kong' >Hong Kong</option><option value='Hungary' >Hungary</option><option value='Iceland' >Iceland</option><option value='India' >India</option><option value='Indonesia' >Indonesia</option><option value='Iran' >Iran</option><option value='Iraq' >Iraq</option><option value='Ireland' >Ireland</option><option value='Isle of Man' >Isle of Man</option><option value='Israel' >Israel</option><option value='Italy' >Italy</option><option value='Jamaica' >Jamaica</option><option value='Japan' >Japan</option><option value='Jersey' >Jersey</option><option value='Jordan' >Jordan</option><option value='Kazakhstan' >Kazakhstan</option><option value='Kenya' >Kenya</option><option value='Kiribati' >Kiribati</option><option value='Kuwait' >Kuwait</option><option value='Kyrgyzstan' >Kyrgyzstan</option><option value='Lao People's Democratic Republic' >Lao People's Democratic Republic</option><option value='Latvia' >Latvia</option><option value='Lebanon' >Lebanon</option><option value='Lesotho' >Lesotho</option><option value='Liberia' >Liberia</option><option value='Libya' >Libya</option><option value='Liechtenstein' >Liechtenstein</option><option value='Lithuania' >Lithuania</option><option value='Luxembourg' >Luxembourg</option><option value='Macau' >Macau</option><option value='Macedonia' >Macedonia</option><option value='Madagascar' >Madagascar</option><option value='Malawi' >Malawi</option><option value='Malaysia' >Malaysia</option><option value='Maldives' >Maldives</option><option value='Mali' >Mali</option><option value='Malta' >Malta</option><option value='Marshall Islands' >Marshall Islands</option><option value='Martinique' >Martinique</option><option value='Mauritania' >Mauritania</option><option value='Mauritius' >Mauritius</option><option value='Mayotte' >Mayotte</option><option value='Mexico' >Mexico</option><option value='Micronesia' >Micronesia</option><option value='Moldova' >Moldova</option><option value='Monaco' >Monaco</option><option value='Mongolia' >Mongolia</option><option value='Montenegro' >Montenegro</option><option value='Montserrat' >Montserrat</option><option value='Morocco' >Morocco</option><option value='Mozambique' >Mozambique</option><option value='Myanmar' >Myanmar</option><option value='Namibia' >Namibia</option><option value='Nauru' >Nauru</option><option value='Nepal' >Nepal</option><option value='Netherlands' >Netherlands</option><option value='New Caledonia' >New Caledonia</option><option value='New Zealand' >New Zealand</option><option value='Nicaragua' >Nicaragua</option><option value='Niger' >Niger</option><option value='Nigeria' >Nigeria</option><option value='Niue' >Niue</option><option value='Norfolk Island' >Norfolk Island</option><option value='North Korea' >North Korea</option><option value='Northern Mariana Islands' >Northern Mariana Islands</option><option value='Norway' >Norway</option><option value='Oman' >Oman</option><option value='Pakistan' >Pakistan</option><option value='Palau' >Palau</option><option value='Palestine, State of' >Palestine, State of</option><option value='Panama' >Panama</option><option value='Papua New Guinea' >Papua New Guinea</option><option value='Paraguay' >Paraguay</option><option value='Peru' >Peru</option><option value='Philippines' >Philippines</option><option value='Pitcairn' >Pitcairn</option><option value='Poland' >Poland</option><option value='Portugal' >Portugal</option><option value='Puerto Rico' >Puerto Rico</option><option value='Qatar' >Qatar</option><option value='Romania' >Romania</option><option value='Russia' >Russia</option><option value='Rwanda' >Rwanda</option><option value='Réunion' >Réunion</option><option value='Saint Barthélemy' >Saint Barthélemy</option><option value='Saint Helena' >Saint Helena</option><option value='Saint Kitts and Nevis' >Saint Kitts and Nevis</option><option value='Saint Lucia' >Saint Lucia</option><option value='Saint Martin' >Saint Martin</option><option value='Saint Pierre and Miquelon' >Saint Pierre and Miquelon</option><option value='Saint Vincent and the Grenadines' >Saint Vincent and the Grenadines</option><option value='Samoa' >Samoa</option><option value='San Marino' >San Marino</option><option value='Sao Tome and Principe' >Sao Tome and Principe</option><option value='Saudi Arabia' >Saudi Arabia</option><option value='Senegal' >Senegal</option><option value='Serbia' >Serbia</option><option value='Seychelles' >Seychelles</option><option value='Sierra Leone' >Sierra Leone</option><option value='Singapore' >Singapore</option><option value='Sint Maarten' >Sint Maarten</option><option value='Slovakia' >Slovakia</option><option value='Slovenia' >Slovenia</option><option value='Solomon Islands' >Solomon Islands</option><option value='Somalia' >Somalia</option><option value='South Africa' >South Africa</option><option value='South Georgia' >South Georgia</option><option value='South Korea' >South Korea</option><option value='South Sudan' >South Sudan</option><option value='Spain' >Spain</option><option value='Sri Lanka' >Sri Lanka</option><option value='Sudan' >Sudan</option><option value='Suriname' >Suriname</option><option value='Svalbard and Jan Mayen Islands' >Svalbard and Jan Mayen Islands</option><option value='Sweden' >Sweden</option><option value='Switzerland' >Switzerland</option><option value='Syria' >Syria</option><option value='Taiwan' >Taiwan</option><option value='Tajikistan' >Tajikistan</option><option value='Tanzania' >Tanzania</option><option value='Thailand' >Thailand</option><option value='Timor-Leste' >Timor-Leste</option><option value='Togo' >Togo</option><option value='Tokelau' >Tokelau</option><option value='Tonga' >Tonga</option><option value='Trinidad and Tobago' >Trinidad and Tobago</option><option value='Tunisia' >Tunisia</option><option value='Turkey' >Turkey</option><option value='Turkmenistan' >Turkmenistan</option><option value='Turks and Caicos Islands' >Turks and Caicos Islands</option><option value='Tuvalu' >Tuvalu</option><option value='US Minor Outlying Islands' >US Minor Outlying Islands</option><option value='Uganda' >Uganda</option><option value='Ukraine' >Ukraine</option><option value='United Arab Emirates' >United Arab Emirates</option><option value='United Kingdom' >United Kingdom</option><option value='United States' selected='selected'>United States</option><option value='Uruguay' >Uruguay</option><option value='Uzbekistan' >Uzbekistan</option><option value='Vanuatu' >Vanuatu</option><option value='Venezuela' >Venezuela</option><option value='Vietnam' >Vietnam</option><option value='Virgin Islands, British' >Virgin Islands, British</option><option value='Virgin Islands, U.S.' >Virgin Islands, U.S.</option><option value='Wallis and Futuna' >Wallis and Futuna</option><option value='Western Sahara' >Western Sahara</option><option value='Yemen' >Yemen</option><option value='Zambia' >Zambia</option><option value='Zimbabwe' >Zimbabwe</option><option value='Åland Islands' >Åland Islands</option></select></div></div><div id="field_5_10" class="gfield gfield--type-select gfield--width-half field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_10" ><label class='gfield_label gform-field-label' for='input_5_10'>States</label><div class='ginput_container ginput_container_select'><select name='input_10' id='input_5_10' class='large gfield_select' aria-invalid="false" ><option value='Alabama' >Alabama</option><option value='Alaska' >Alaska</option><option value='Arizona' >Arizona</option><option value='Arkansas' >Arkansas</option><option value='California' >California</option><option value='Colorado' >Colorado</option><option value='Connecticut' >Connecticut</option><option value='Delaware' >Delaware</option><option value='District of Columbia' >District of Columbia</option><option value='Florida' >Florida</option><option value='Georgia' >Georgia</option><option value='Hawaii' >Hawaii</option><option value='Idaho' >Idaho</option><option value='Illinois' >Illinois</option><option value='Indiana' >Indiana</option><option value='Iowa' >Iowa</option><option value='Kansas' >Kansas</option><option value='Kentucky' >Kentucky</option><option value='Louisiana' >Louisiana</option><option value='Maine' >Maine</option><option value='Maryland' >Maryland</option><option value='Massachusetts' >Massachusetts</option><option value='Michigan' >Michigan</option><option value='Minnesota' >Minnesota</option><option value='Mississippi' >Mississippi</option><option value='Missouri' >Missouri</option><option value='Montana' >Montana</option><option value='Nebraska' >Nebraska</option><option value='Nevada' >Nevada</option><option value='New Hampshire' >New Hampshire</option><option value='New Jersey' >New Jersey</option><option value='New Mexico' >New Mexico</option><option value='New York' >New York</option><option value='North Carolina' >North Carolina</option><option value='North Dakota' >North Dakota</option><option value='Ohio' >Ohio</option><option value='Oklahoma' >Oklahoma</option><option value='Oregon' >Oregon</option><option value='Pennsylvania' >Pennsylvania</option><option value='Rhode Island' >Rhode Island</option><option value='South Carolina' >South Carolina</option><option value='South Dakota' >South Dakota</option><option value='Tennessee' >Tennessee</option><option value='Texas' >Texas</option><option value='Utah' >Utah</option><option value='Vermont' >Vermont</option><option value='Virginia' >Virginia</option><option value='Washington' >Washington</option><option value='West Virginia' >West Virginia</option><option value='Wisconsin' >Wisconsin</option><option value='Wyoming' >Wyoming</option></select></div></div><div id="field_5_12" class="gfield gfield--type-text gfield--width-full field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_12" ><label class='gfield_label gform-field-label' for='input_5_12'>Province/Region</label><div class='ginput_container ginput_container_text'><input name='input_12' id='input_5_12' type='text' value='' class='large' aria-invalid="false" /> </div></div><fieldset id="field_5_17" class="gfield gfield--type-checkbox gfield--type-choice gfield--width-third gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_17" ><legend class='gfield_label gform-field-label gfield_label_before_complex' >Cytokine Use<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></legend><div class='ginput_container ginput_container_checkbox'><div class='gfield_checkbox' id='input_5_17'><div class='gchoice gchoice_5_17_1'> <input class='gfield-choice-input' name='input_17.1' type='checkbox' value='RUO' id='choice_5_17_1' /> <label for='choice_5_17_1' id='label_5_17_1' class='gform-field-label gform-field-label--type-inline'>RUO</label> </div><div class='gchoice gchoice_5_17_2'> <input class='gfield-choice-input' name='input_17.2' type='checkbox' value='GMP' id='choice_5_17_2' /> <label for='choice_5_17_2' id='label_5_17_2' class='gform-field-label gform-field-label--type-inline'>GMP</label> </div></div></div></fieldset><fieldset id="field_5_18" class="gfield gfield--type-checkbox gfield--type-choice gfield--width-third gfield_contains_required field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_18" ><legend class='gfield_label gform-field-label gfield_label_before_complex' >Cytokine Type<span class="gfield_required"><span class="gfield_required gfield_required_text">(Required)</span></span></legend><div class='ginput_container ginput_container_checkbox'><div class='gfield_checkbox' id='input_5_18'><div class='gchoice gchoice_5_18_1'> <input class='gfield-choice-input' name='input_18.1' type='checkbox' value='IL-2' id='choice_5_18_1' /> <label for='choice_5_18_1' id='label_5_18_1' class='gform-field-label gform-field-label--type-inline'>IL-2</label> </div><div class='gchoice gchoice_5_18_2'> <input class='gfield-choice-input' name='input_18.2' type='checkbox' value='IL-7' id='choice_5_18_2' /> <label for='choice_5_18_2' id='label_5_18_2' class='gform-field-label gform-field-label--type-inline'>IL-7</label> </div><div class='gchoice gchoice_5_18_3'> <input class='gfield-choice-input' name='input_18.3' type='checkbox' value='IL-15' id='choice_5_18_3' /> <label for='choice_5_18_3' id='label_5_18_3' class='gform-field-label gform-field-label--type-inline'>IL-15</label> </div><div class='gchoice gchoice_5_18_4'> <input class='gfield-choice-input' name='input_18.4' type='checkbox' value='IL-21' id='choice_5_18_4' /> <label for='choice_5_18_4' id='label_5_18_4' class='gform-field-label gform-field-label--type-inline'>IL-21</label> </div><div class='gchoice gchoice_5_18_5'> <input class='gfield-choice-input' name='input_18.5' type='checkbox' value='Other' id='choice_5_18_5' /> <label for='choice_5_18_5' id='label_5_18_5' class='gform-field-label gform-field-label--type-inline'>Other</label> </div></div></div></fieldset><fieldset id="field_5_19" class="gfield gfield--type-checkbox gfield--type-choice gfield--width-third field_sublabel_below gfield--no-description field_description_below field_validation_below gfield_visibility_visible" data-js-reload="field_5_19" ><legend class='gfield_label gform-field-label gfield_label_before_complex' >Formulation</legend><div class='ginput_container ginput_container_checkbox'><div class='gfield_checkbox' id='input_5_19'><div class='gchoice gchoice_5_19_1'> <input class='gfield-choice-input' name='input_19.1' type='checkbox' value='Liquid' id='choice_5_19_1' /> <label for='choice_5_19_1' 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Select high quality raw materials from the beginning.<br /> - Michael Paglia<br /> Chief Operating Officer<br /> Elevate Bio, BaseCamp</div> </div> </div> </div> </div> <h2 class="color-deep-blue h3 small-text-36-42 title mb-40 smb-30">Additional GMP Cytokine resources</h2> <div class="row medium-type"> <div class="columns small-12 medium-6 large-4 mb-50 smb-50 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box small full-height su"> <h3 class="text-26-32 color-deep-blue title">GMP Cytokines Optimization for Closed System T Cell Therapy Manufacturing</h3> <div class="text-18-24 mb-15 smb-40 text"> In this case study, a company focused on autologous T cell therapies targeting solid tumor cancers was progressing into clinical trials and needed to transition from research-grade to GMP-grade cytokines. Concurrently they wanted to improve their methods of cytokine supplementation to reduce cytokine waste, improve dose accuracy across lots, and reduce process risk by defining methods for closed-system cytokine addition. ScaleReady detailed a plan to help them achieve these goals. </div> <div class="flex-container align-right text-21-28 ff-pnsb"> <a target="_blank" href="https://www.scaleready.com/wp-content/uploads/2021/11/ScaleReady_CaseStudy_GMPCytokineTransition-2.pdf">Download</a> </div> </div> </div> <div class="columns small-12 medium-6 large-4 mb-50 smb-50 position-relative"> <div class="revealator-slideup rev-item"></div> <div class="bg-smoke box-shadow-20 border-radius-32 l-box small full-height su"> <h3 class="text-26-32 color-deep-blue title">Determining Optimal Seeding Density for Human T Cell Expansion in G-Rex</h3> <div class="text-18-24 mb-15 smb-40 text"> This scientific poster investigates the kinetics of human T cell expansion in small scale G-Rex6M bioreactors using ScaleReady reagents. 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