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Effect of <span class="highlight-field">esketamine</span> on reducing postpartum pain and depression. <em class='incite-journal-name' onclick='ShowInCiteJournal(23577);'>World J Clin Cases</em> 2025;<b>13</b>:100422. [DOI: <a href='https://dx.doi.org/10.12998/wjcc.v13.i7.100422' target='_blank'>10.12998/wjcc.v13.i7.100422</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.12998/wjcc.v13.i7.100422','', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(1);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(1);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.wjgnet.com/2307-8960/full/v13/i7/100422.htm' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.f6publishing.com/forms/main/DownLoadFile.aspx?Type=Digital&TypeId=1&id=10.12998%2fwjcc.v13.i7.100422&FilePath=78E582E700BBC34AABB6905ADBFC089E8D35F91B2412C26C7B78CB6EC00422CB218987717BCEC60AD669FFA6B143D27743CFC6193F716E86C27DC23197D46F36D8D5C6699BB25833' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(23577);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.f6publishing.com/' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/15/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 11/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/25/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv1" value="10.12998/wjcc.v13.i7.100422" /> <div style="display: none" id="articleAbstract1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <p>In this editorial, we comment on a recent article by Chen <i>et al</i>, that addressed the effect of intraoperative injection of esketamine on postoperative analgesia and postoperative rehabilitation after cesarean section. Poor management of post-cesarean pain is associated with decreased maternal care for the baby, longer hospitalization, and higher risk of developing postpartum depression. Esketamine is a more potent S-enantiomer of ketamine which has shown promising analgesic and antidepressant properties for managing post-cesarean pain and depression in clinical studies. However, due to its potential adverse effects on the neurological and hemodynamic status of patients, it is recommended that its usage in low doses should be limited to cesarean candidates experiencing unbearable pain. Before any recommendation for routine perioperative use of esketamine, more standardized clinical trials are needed to strengthen our existing knowledge of its effectiveness in reducing postpartum pain and depression.</p> <a href="javascript:ShowArticleAbstract(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cesarean+section%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cesarean section</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postpartum+pain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postpartum pain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postpartum+depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postpartum depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+analgesia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative analgesia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li></ul> <a href="javascript:ShowArticleKeywords(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(1);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant1" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(1);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow2"> <td style="min-width: 40px; text-align: center;"> 2 </td> <td> <div id="citation2" class="article-citation"> <b>Zang X</b>, Zhang J, Hu J, Mo X, Zheng T, Ji J, Xing J, Chen C, Zhou S. Electroconvulsive therapy combined with <span class="highlight-field">esketamine</span> improved depression through PI3K/AKT/GLT-1 pathway. <em class='incite-journal-name' onclick='ShowInCiteJournal(13076);'>J Affect Disord</em> 2025;<b>368</b>:282-294. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39265873' target='_blank'>39265873</a> DOI: <a href='https://dx.doi.org/10.1016/j.jad.2024.08.123' target='_blank'>10.1016/j.jad.2024.08.123</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jad.2024.08.123','39265873', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(2);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(2);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(2);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jad.2024.08.123' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13076);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/jafd/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/18/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/14/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv2" value="10.1016/j.jad.2024.08.123" /> <div style="display: none" id="articleAbstract2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Neuron excitotoxic damage induced by extracellular glutamate accumulation pathologically is one of the main mechanisms of depression. Glutamate transporter-1 (GLT-1) expressed in astrocyte is responsible for glutamate clearance to maintain glutamate balance. Electroconvulsive therapy (ECT) is prevalently recommended for severe depression due to its significant anti-depressant effect. Esketamine could offer advantages of rapid anti-depressant effect and neuron protection. The aim of this study is to investigate the anti-depressant efficacy of esketamine plus ECT, and further to explore the mechanism. Firstly, total 12 patients were randomized into anesthesia with propofol (P) or propofol+esketamine (PK) before ECT. 24-Hamilton Depression Scale (HAMD) was used to evaluate the severity of depression after each ECT. Then, depressive rat model was built using chronic unpredictable mild stress method, and subsequently received infusion of esketamine (5 mg/kg) or saline before ECT treatment (0.5 mA; 100 V) for consecutive 10 days. Tests including sucrose preference test, open field test and forced swimming test were used to evaluate depression-like behaviors. In next experiments, rats were injected with RIL, DHK or LY294002 intracerebroventricularly for continuous 10 days before individual treatment. After the fifth and sixth ECT, PK group displayed lower HAMD score compared to P group. In rat model, we found that esketamine plus ECT could significantly improve depression-like behaviors and decrease glutamate level. Esketamine and ECT could both activate PI3K/Akt/GLT-1 pathway. The GLT-1 agonist RIL made equivalent effect as esketamine plus ECT. Furthermore, after using PI3K/Akt inhibitor LY294002 and GLT-1 inhibitor DHK, esketamine plus ECT could neither improve depression-like symptoms, nor upregulate GLT-1 level. Our present study suggested that esketamine plus ECT could dramatically improve depression symptom. The activation of PI3K/Akt/GLT-1 pathway may be the potential mechanism. </div> <a href="javascript:ShowArticleAbstract(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Electroconvulsive+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Electroconvulsive therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glutamate%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glutamate</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Glutamate+transporter%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Glutamate transporter</a></li></ul> <a href="javascript:ShowArticleKeywords(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Electroconvulsive+Therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Electroconvulsive Therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Chromones%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Chromones/pharmacology</a></li></ul> <a href="javascript:ShowArticleMeSH(2);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant2" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(2);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow3"> <td style="min-width: 40px; text-align: center;"> 3 </td> <td> <div id="citation3" class="article-citation"> <b>Zeng QB</b>, Zou DC, Huang XB, Shang DW, Huang X, Yang XH, Ning YP, Balbuena L, Xiang YT, Zheng W. Efficacy and safety of <span class="highlight-field">esketamine</span> versus propofol in electroconvulsive therapy for treatment-resistant depression: A randomized, double-blind, controlled, non-inferiority trial. <em class='incite-journal-name' onclick='ShowInCiteJournal(13076);'>J Affect Disord</em> 2025;<b>368</b>:320-328. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39265871' target='_blank'>39265871</a> DOI: <a href='https://dx.doi.org/10.1016/j.jad.2024.09.038' target='_blank'>10.1016/j.jad.2024.09.038</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jad.2024.09.038','39265871', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(3);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(3);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(3);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jad.2024.09.038' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13076);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/jafd/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/08/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/14/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv3" value="10.1016/j.jad.2024.09.038" /> <div style="display: none" id="articleAbstract3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Electroconvulsive therapy (ECT) is a commonly used alternative for treatment-resistant depression (TRD). Although esketamine has a rapid pharmacological antidepressant action, it has not been studied as an ECT anesthetic. The objective of this study was to compare the efficacy and safety of esketamine with propofol when both are used as ECT anesthetic agents. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Forty patients with TRD were assigned to one of two arms in a double-blind, randomized controlled trial: esketamine or propofol anesthesia for a series of eight ECT sessions. Using a non-inferiority design, the primary outcome was the reduction in HAMD-17 depressive symptoms. The other outcomes were: rates of response and remission, anxiety, suicidal ideation, cognitive function, and adverse events. These were compared in an intention-to-treat analysis. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Esketamine-ECT was non-inferior to propofol-ECT for reducing TRD symptoms after 8 sessions (adjusted Δ = 2.0, 95 % CI: -1.2-5.1). Compared to propofol-ECT, esketamine-ECT also had higher depression response (80 % vs. 70 %; p = .06) and remission (65 % vs. 55 %; p = .11) rates but non-inferiority was not established. In four components of cognitive function (speed of processing, working memory, visual learning, and verbal learning) esketamine-ECT was non-inferior to propofol-ECT. The results for anxiety, suicidal ideation, and adverse events (all p's > .05) were inconclusive. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Esketamine was non-inferior to propofol when both are used as anesthetics for TRD patients undergoing ECT. Replication studies with larger samples are needed to examine the inconclusive results. </div><div class="abstract-label">REGISTRATION NUMBER</div><div class="abstract-content">ChiCTR2000033715. </div> <a href="javascript:ShowArticleAbstract(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Electroconvulsive+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Electroconvulsive therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RCT%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">RCT</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Treatment-resistant+depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Treatment-resistant depression</a></li></ul> <a href="javascript:ShowArticleKeywords(3);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh3" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthetics%2c+Intravenous%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthetics, Intravenous/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthetics%2c+Intravenous%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthetics, Intravenous/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Treatment-Resistant%2ftherapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" 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effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Suicidal+Ideation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Suicidal Ideation</a></li><li><a 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Merits and demerits of administering <span class="highlight-field">esketamine</span> in preventing postpartum depression following cesarean section. <em class='incite-journal-name' onclick='ShowInCiteJournal(23577);'>World J Clin Cases</em> 2024;<b>12</b>:6883-6886. [DOI: <a href='https://dx.doi.org/10.12998/wjcc.v12.i36.6883' target='_blank'>10.12998/wjcc.v12.i36.6883</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.12998/wjcc.v12.i36.6883','', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(4);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(4);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.wjgnet.com/2307-8960/full/v12/i36/6883.htm' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.f6publishing.com/forms/main/DownLoadFile.aspx?Type=Digital&TypeId=1&id=10.12998%2fwjcc.v12.i36.6883&FilePath=C29E2D13D4FBF584C0FF6DD8300811BFD8A32A56D27D470A145BC73EF25DF0413EE4070B64033385FE6B1C6DA943A33108278C0DDF500CBF3135680283192A1F8EDF3D1B24E00647' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(23577);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.f6publishing.com/' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/31/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv4" value="10.12998/wjcc.v12.i36.6883" /> <div style="display: none" id="articleAbstract4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <p>Emergency cesarean section is associated with the development of postpartum depression. Esketamine has been demonstrated to have a rapid onset of antidepressant effects. Randomized controlled trials and meta-analyses have demon<Hypen />strated the efficacy of esketamine in preventing postpartum depression after ce<Hypen />ssarean section. However, the data included in these analyses were derived from elective cesarean sections and differed in the dose and timing of esketamine ad<Hypen />ministration. Esketamine is a dissociative anesthetic with a dose-dependent risk of inducing psychotic symptoms, including hallucinations. In the setting of cesarean section, esketamine should be administered with caution and only if the potential benefits outweigh the risks.</p> <a href="javascript:ShowArticleAbstract(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cesarean+section%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cesarean section</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adverse+event%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adverse event</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Medial+prefrontal+cortex%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Medial prefrontal cortex</a></li></ul> <a href="javascript:ShowArticleKeywords(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(4);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant4" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(4);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow5"> <td style="min-width: 40px; text-align: center;"> 5 </td> <td> <div id="citation5" class="article-citation"> <b>Shi J</b>, Song S, Wang Y, Wu K, Liang G, Wang A, Xu X. <span class="highlight-field">Esketamine</span> alleviates ferroptosis-mediated acute lung injury by modulating the HIF-1α/HO-1 pathway. <em class='incite-journal-name' onclick='ShowInCiteJournal(11367);'>Int Immunopharmacol</em> 2024;<b>142</b>:113065. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39243557' target='_blank'>39243557</a> DOI: <a href='https://dx.doi.org/10.1016/j.intimp.2024.113065' target='_blank'>10.1016/j.intimp.2024.113065</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.intimp.2024.113065','39243557', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(5);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(5);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(5);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.intimp.2024.113065' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(11367);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/09/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv5" value="10.1016/j.intimp.2024.113065" /> <div style="display: none" id="articleAbstract5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Alveolar epithelial cell (AEC) ferroptosis contributes to the progression of acute lung injury (ALI). Esketamine (ESK) is a new clinical sedative, anesthetic, and analgesic drug that has attracted substantial attention in mental health research because of its antidepressant effects. However, the effects of ESK on ferroptosis-mediated ALI remain unclear. </div><div class="abstract-label">OBJECTIVE</div><div class="abstract-content">This study aimed to explore the protective effect of ESK on AEC ferroptosis in ALI and its potential molecular mechanism in vivo and in vitro. </div><div class="abstract-label">METHODS</div><div class="abstract-content">The antiferroptotic and anti-inflammatory effects of ESK were assessed in a mouse model of lipopolysaccharide (LPS)-induced ALI. In vitro, the epithelial cell lines MLE-12 and A549 were used to examine the underlying mechanism by which ESK regulates inflammation and ferroptosis. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">ESK protected mice against LPS-induced ALI, significantly attenuated pathological changes in the lungs and decreased inflammation and ferroptosis. In vitro, ESK inhibited LPS-induced inflammation and ferroptosis in MLE-12 and A549 cells. Moreover, ferroptosis mediated inflammation in LPS-induced ALI in vivo and in vitro, and ESK decreased the LPS-induced inflammatory response by suppressing ferroptosis. ESK promoted the HIF-1α/HO-1 pathway in LPS-treated AECs and in the lung tissues of mice with LPS-induced ALI. Moreover, pretreatment with ESK and the HIF-1α stabilizer dimethyloxaloylglycine (DMOG) substantially attenuated lung injury and prevented changes in ferroptosis-related biochemical indicators, including glutathione (GSH) depletion, malondialdehyde (MDA) production and glutathione peroxidase 4 (GPX4) downregulation, in untreated LPS-induced mice but not in LPS-induced mice treated with the HO-1 inhibitor zinc protoporphyrin (ZNPP). Similar effects were observed in vitro in HO-1 siRNA-transfected A549 cells after LPS incubation but not in control siRNA-transfected cells. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">ESK can inhibit ferroptosis-mediated lipid peroxidation by increasing the expression of HIF-1α/HO-1 pathway, highlighting the potential of ESK to treat LPS-induced ALI. </div> <a href="javascript:ShowArticleAbstract(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+lung+injury%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute lung injury</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alveolar+epithelial+cell%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alveolar epithelial cell</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ferroptosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ferroptosis</a></li></ul> <a href="javascript:ShowArticleKeywords(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22A549+Cells%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">A549 Cells</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Lung+Injury%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Lung Injury/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Lung+Injury%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Lung Injury/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Acute+Lung+Injury%2fchemically+induced%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Acute Lung Injury/chemically induced</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alveolar+Epithelial+Cells%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" 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href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mice%2c+Inbred+C57BL%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mice, Inbred C57BL</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li></ul> <a href="javascript:ShowArticleMeSH(5);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant5" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(5);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow6"> <td style="min-width: 40px; text-align: center;"> 6 </td> <td> <div id="citation6" class="article-citation"> <b>Wang M</b>, Liu J, Dong R. <span class="highlight-field">Esketamine</span> in postoperative recovery: Reliable for negative emotional relief, ambiguous for cognitive function. <em class='incite-journal-name' onclick='ShowInCiteJournal(13320);'>J Clin Anesth</em> 2024;<b>99</b>:111641. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39362057' target='_blank'>39362057</a> DOI: <a href='https://dx.doi.org/10.1016/j.jclinane.2024.111641' target='_blank'>10.1016/j.jclinane.2024.111641</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jclinane.2024.111641','39362057', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(6);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jclinane.2024.111641' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13320);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 09/17/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/05/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv6" value="10.1016/j.jclinane.2024.111641" /> <div style="display: none" id="articleAbstract6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <a href="javascript:ShowArticleAbstract(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Negative+emotion%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Negative emotion</a></li></ul> <a href="javascript:ShowArticleKeywords(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(6);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant6" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(6);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow7"> <td style="min-width: 40px; text-align: center;"> 7 </td> <td> <div id="citation7" class="article-citation"> <b>Huang XM</b>, Qiu HX. Effect of intravenous <span class="highlight-field">esketamine</span> in emergency cesarean deliveries: a retrospective analysis of maternal and neonatal outcomes. <em class='incite-journal-name' onclick='ShowInCiteJournal(168648);'>J Matern Fetal Neonatal Med</em> 2024;<b>37</b>:2413855. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39396881' target='_blank'>39396881</a> DOI: <a href='https://dx.doi.org/10.1080/14767058.2024.2413855' target='_blank'>10.1080/14767058.2024.2413855</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/14767058.2024.2413855','39396881', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(7);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(7);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(7);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/14767058.2024.2413855' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(168648);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/12/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/03/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/15/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv7" value="10.1080/14767058.2024.2413855" /> <div style="display: none" id="articleAbstract7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">This study investigates the effects of administering intravenous esketamine at a dose of 0.25 mg/kg to pregnant patients receiving epidural anesthesia for emergency cesarean section on both maternal and neonatal outcomes. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Medical records of pregnant patients transitioning from labor analgesia to epidural anesthesia for emergency cesarean sections between January 2020 and December 2022 were analyzed. The patients were categorized based on whether they received esketamine infusions during the incision-to-delivery interval. The variables compared between the groups included hemodynamic parameters, perioperative and postoperative adverse reactions, and neonatal outcomes (gender, weight, Apgar scores at 1 and 5 min, need for neonatal intensive care, and umbilical artery/vein blood gas analysis). </div><div class="abstract-label">RESULTS</div><div class="abstract-content">For maternal outcomes, the systolic blood pressure (SBP) in the esketamine group showed a significant increase at 5 and 10 min' post-administration, and the diastolic blood pressure (DBP) significantly increased at 5 min, compared to the control group (p < 0.01). No significant differences were observed in heart rate (HR) and oxygen saturation (SpO2) at any time point (p > 0.05). The esketamine group experienced a significant rise in the incidence of arrhythmias, dizziness, and nystagmus during the perioperative period, a notable decrease in hypotension incidence, and an increase in postoperative nausea and dizziness. Regarding neonatal outcomes, there were no significant differences in gender, weight, Apgar scores ≤7 at 1 and 5 min, and the need for neonatal intensive care. However, the pH level in the umbilical artery blood of the esketamine group was significantly higher. The levels of PCO2 and PO2 in umbilical artery and venous blood did not show significant differences between the groups. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">In pregnant women undergoing emergency cesarean section, intravenous administration of 0.25 mg/kg esketamine is correlated with favorable maternal and neonatal outcomes. </div> <a href="javascript:ShowArticleAbstract(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22emergency+cesarean+section%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">emergency cesarean section</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22maternal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">maternal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22neonatal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">neonatal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22outcomes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">outcomes</a></li></ul> <a href="javascript:ShowArticleKeywords(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pregnancy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pregnancy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cesarean+Section%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cesarean Section</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Retrospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Retrospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infant%2c+Newborn%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infant, Newborn</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthesia%2c+Obstetrical%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthesia, Obstetrical/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthesia%2c+Obstetrical%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthesia, Obstetrical/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthesia%2c+Epidural%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthesia, Epidural/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Infusions%2c+Intravenous%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Infusions, Intravenous</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Apgar+Score%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Apgar Score</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pregnancy+Outcome%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pregnancy Outcome/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Administration%2c+Intravenous%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Administration, Intravenous</a></li></ul> <a href="javascript:ShowArticleMeSH(7);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant7" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(7);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow8"> <td style="min-width: 40px; text-align: center;"> 8 </td> <td> <div id="citation8" class="article-citation"> <b>Nikula A</b>, Rinder MR, Lundeberg S, Lääperi M, Sandholm K, Castrén M, Kurland L. A randomized clinical trial of intranasal dexmedetomidine versus inhaled nitrous oxide for procedural sedation and analgesia in children. <em class='incite-journal-name' onclick='ShowInCiteJournal(20890);'>Scand J Trauma Resusc Emerg Med</em> 2024;<b>32</b>:117. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39568028' target='_blank'>39568028</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11577660' target='_blank'>PMC11577660</a> DOI: <a href='https://dx.doi.org/10.1186/s13049-024-01292-0' target='_blank'>10.1186/s13049-024-01292-0</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s13049-024-01292-0','39568028', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(8);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(8);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(8);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(8);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1186/s13049-024-01292-0' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20890);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/26/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/13/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/22/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv8" value="10.1186/s13049-024-01292-0" /> <div style="display: none" id="articleAbstract8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Procedural sedation and analgesia is an important part of pediatric emergency care, safe and clinically useful alternatives for adequate management are necessary. The objective of this clinical trial was to evaluate the non-inferiority of intranasal dexmedetomidine to nitrous oxide with respect to analgesia for a painful procedure in children 3-15 years of age. </div><div class="abstract-label">METHODS</div><div class="abstract-content">This prospective, equally randomized, open-label, non-inferiority trial was conducted at a Pediatric Emergency Department. Previously healthy children 3-15 years of age, with an extremity fracture or luxation or a burn and requiring procedural sedation and analgesia were eligible. Patients were randomized to receive either intranasal dexmedetomidine or inhaled nitrous oxide. The primary outcome measure was highest pain level during the procedure, assessed with Face, Legs, Activity, Cry, Consolability scale (FLACC). Mann-Whitney U test (continuous variables) and Fisher's test (categorical variables) were used for statistical analysis. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">The highest FLACC was median 4 (IQR 3-6) with intranasal dexmedetomidine and median 4 (IQR 2-6) with nitrous oxide. The median of the difference between samples from each group for FLACC was 0 with 95%CI (0-1), thus intranasal dexmedetomidine was not inferior to nitrous oxide with respect to the level of pain during the procedure. The same method for procedural sedation and analgesia would be accepted by 52/74 (82.5%) children and 65/74 (91.5%) parents in the intranasal dexmedetomidine group respectively 59/74 (88.1%) versus 70/74 (94.6%) with nitrous oxide. No serious adverse events were reported. </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">The results of this trial support that intranasal dexmedetomidine is not inferior to 50% nitrous oxide in providing analgesia for a painful procedure in children 3-15 years of age and can be considered as an alternative to 50% nitrous oxide for procedural sedation and analgesia. </div><div class="abstract-label">TRIAL REGISTRATION</div><div class="abstract-content">EudraCT 201,600,377,317, April 20, 2017. https://eudract.ema.europa.eu/ . </div> <a href="javascript:ShowArticleAbstract(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Analgesia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Analgesia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Children%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Children</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dexmedetomidine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dexmedetomidine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Intranasal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Intranasal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Procedure%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Procedure</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sedation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sedation</a></li></ul> <a href="javascript:ShowArticleKeywords(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dexmedetomidine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dexmedetomidine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Nitrous+Oxide%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Nitrous Oxide/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Administration%2c+Intranasal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Administration, Intranasal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Child%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Child</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Child%2c+Preschool%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Child, Preschool</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescent%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescent</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypnotics+and+Sedatives%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypnotics and Sedatives/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Conscious+Sedation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Conscious Sedation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pain+Measurement%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pain Measurement</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pain+Management%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pain Management/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Administration%2c+Inhalation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Administration, Inhalation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Analgesics%2c+Non-Narcotic%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Analgesics, Non-Narcotic/administration & dosage</a></li></ul> <a href="javascript:ShowArticleMeSH(8);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant8" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22University+of+Helsinki+(including+Helsinki+University+Central+Hospital)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">University of Helsinki (including Helsinki University Central Hospital)</a></li></ul> <a href="javascript:ShowArticleGrant(8);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow9"> <td style="min-width: 40px; text-align: center;"> 9 </td> <td> <div id="citation9" class="article-citation"> <b>Li H</b>, Hu W, Wu Z, Tian B, Ren Y, Zou X. <span class="highlight-field">Esketamine</span> improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation. <em class='incite-journal-name' onclick='ShowInCiteJournal(8802);'>Eur J Pharmacol</em> 2024;<b>983</b>:177014. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39312992' target='_blank'>39312992</a> DOI: <a href='https://dx.doi.org/10.1016/j.ejphar.2024.177014' target='_blank'>10.1016/j.ejphar.2024.177014</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.ejphar.2024.177014','39312992', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(9);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(9);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(9);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.ejphar.2024.177014' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8802);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 09/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/25/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv9" value="10.1016/j.ejphar.2024.177014" /> <div style="display: none" id="articleAbstract9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Microglia-mediated neuroinflammation is critical in the pathogenesis of sepsis-associated encephalopathy(SAE). Identifying the key factors that inhibit microglia-mediated neuroinflammation holds promise as a potential target for preventing and treating SAE. Esketamine, a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist, has been proposed to possess protective and therapeutic properties against neuroinflammatory disorders. This study provides evidence that the administration of Esketamine in SAE mice improves cognitive impairments and alleviates neuronal damage by inhibiting the microglia-mediated neuroinflammation. The BDNF receptor antagonist K252a was employed in both vivo and in vitro experiments. The findings indicate that K252a successfully counteracted the beneficial effects of Esketamine on microglia and cognitive behavior in mice with SAE. Consequently, these results suggest that Esketamine inhibits microglia-mediated neuroinflammation by activating the BDNF pathway, and mitigating neuronal damage and cognitive dysfunction associated with SAE. </div> <a href="javascript:ShowArticleAbstract(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22BDNF%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">BDNF</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a 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target="_blank">Neurons/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurons%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurons/pathology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Carbazoles%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Carbazoles</a></li></ul> <a href="javascript:ShowArticleMeSH(9);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant9" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(9);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow10"> <td style="min-width: 40px; text-align: center;"> 10 </td> <td> <div id="citation10" class="article-citation"> <b>Wang L</b>, Zhao S, Shao J, Su C. The effect and mechanism of low-dose <span class="highlight-field">esketamine</span> in neuropathic pain-related depression-like behavior in rats. <em class='incite-journal-name' onclick='ShowInCiteJournal(4013);'>Brain Res</em> 2024;<b>1843</b>:149117. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38977235' target='_blank'>38977235</a> DOI: <a href='https://dx.doi.org/10.1016/j.brainres.2024.149117' target='_blank'>10.1016/j.brainres.2024.149117</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.brainres.2024.149117','38977235', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(10);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(10);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(10);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.brainres.2024.149117' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4013);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 05/28/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/05/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv10" value="10.1016/j.brainres.2024.149117" /> <div style="display: none" id="articleAbstract10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Clinical evidence suggests that Esketamine (ESK) is an effective treatment for depression. However, the effects of Esketamine in treating depression-like behavior induced by neuropathic pain is unclear. The underlying molecular mechanisms require further investigation to provide new therapeutic targets for the treatment of clinical neuropathic pain-related depression. </div><div class="abstract-label">METHODS</div><div class="abstract-content">A neuropathic pain-related depression model was established in rats with spared nerve injury (SNI). Male Sprague-Dawley rats were randomly divided into four groups: Sham Group, SNI group, SNI + Normal Saline (NS) Group and SNI + ESK5mg/kg Group. Mechanical pain thresholds were measured to assess pain sensitivity in SNI rats. On the 14th day after surgery a forced swim test and sucrose preference test were used to evaluate the depressive-like behavior of rats in each group. Further, a proteomic analysis was used to quantify differentially expressed proteins. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were analyzed to explore the main protein targets of SNI in the medial prefrontal cortex. The expression of proteins was detected by Western blotting. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">A neuropathic pain-related depression model was established. Compared with the Sham group, the mechanical pain threshold was decreased significantly (13.2 ± 1.0 vs. 0.7 ± 0.01 g n = 8), while immobility on the forced swim test was also decreased (93.1 ± 7.4 vs. 169.5 ± 9.6 s n = 8), and sucrose preference rate was significantly increased (98.8 ± 0.3 vs. 73.1 ± 1.4n = 7) in SNI group rats. Compared with the SNI + NS group, the mechanical pain threshold was not statistically significant, while immobility on the forced swim test was clearly decreased (161.1 ± 11.6 vs. 77.9 ± 5.0 s n = 8), and sucrose preference rate was significantly increased (53.1 ± 8.9 vs. 96.1 ± 1.4n = 7) in SNI + ESK5mg/kg group rats. To further investigate the underlying mechanism, we employed proteomics to identify proteins exhibiting more than a 1.2-fold difference (P < 0.05) in expression levels within each group for subsequent analysis. Relative to the Sham group, 88 downregulated and 104 up-regulated proteins were identified in the SNI group, while 120 and 84 proteins were up- and down-regulated in the Esketamine treatment group compared with the SNI + NS group. Compared with Sham group, the expressions of mGluR5 and Homer1a were up-regulated in the medial prefrontal cortex (mPFC) in SNI group (mGluR5:0.97 ± 0.05 vs 1.47 ± 0.15, Homer1a:1.03 ± 0.06 vs 1.46 ± 0.16n = 6), and down-regulated after intervention with Esketamine (mGluR5:1.54 ± 0.11 vs 1.06 ± 0.07, Homer1a:1.51 ± 0.13 vs 1.12 ± 0.34n = 6). </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">Low-dose Esketamine appeared to relieve depression-like behavior induced by neuropathic pain. The Homer1a-mGluR5 signaling pathway might be the mechanism of antidepressant effect of Esketamine. </div> <a href="javascript:ShowArticleAbstract(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Homer1a%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Homer1a</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuropathic+pain%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuropathic pain</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22mGluR5%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">mGluR5</a></li></ul> <a href="javascript:ShowArticleKeywords(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuralgia%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuralgia/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuralgia%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuralgia/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Disease+Models%2c+Animal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Disease Models, Animal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pain+Threshold%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pain Threshold/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behavior%2c+Animal%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behavior, Animal/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prefrontal+Cortex%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prefrontal Cortex/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prefrontal+Cortex%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prefrontal Cortex/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antidepressive+Agents%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antidepressive Agents/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antidepressive+Agents%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antidepressive Agents/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Proteomics%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Proteomics/methods</a></li></ul> <a href="javascript:ShowArticleMeSH(10);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant10" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(10);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow11"> <td style="min-width: 40px; text-align: center;"> 11 </td> <td> <div id="citation11" class="article-citation"> <b>Zhou L</b>, Wang X, Cao T, Li Y, Jiang S, Huang L. Repeated high-dose <span class="highlight-field">esketamine</span> in early postnatal rats leads to behavioural deficits with long-term modifications in white matter microstructural integrity. <em class='incite-journal-name' onclick='ShowInCiteJournal(4013);'>Brain Res</em> 2024;<b>1847</b>:149311. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39510384' target='_blank'>39510384</a> DOI: <a href='https://dx.doi.org/10.1016/j.brainres.2024.149311' target='_blank'>10.1016/j.brainres.2024.149311</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.brainres.2024.149311','39510384', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(11);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(11);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.brainres.2024.149311' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(4013);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 08/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 10/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 11/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/15/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv11" value="10.1016/j.brainres.2024.149311" /> <div style="display: none" id="articleAbstract11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Esketamine is commonly used for sedation or general anaesthesia in infants and young children. However, repeated esketamine administration during periods of rapid brain growth and development may result in various pathophysiological and cognitive changes. Therefore, this study aimed to investigate the influence of recurrent esketamine exposure on long-term behavioural and white matter consequences. Seven-day-old (P7) male rats were allocated to control, high-, and low-dose groups. Behavioural paradigm assessment was conducted at P25-29. Diffusion tensor imaging revealed long-term effects on water diffusivity in the splenium and cingulum white matter of the corpus callosum at P30. Subsequent two-dimensional structure-tensor analysis of brain tissue sections stained with Luxol fast blue (LFB) showed marked changes in the white matter microstructure in rats after multiple exposures to varying esketamine doses. High-dose esketamine significantly reduced activity time and total distance in the open-field experiment. High-dose esketamine exposure might lead to impaired short-term memory in rats. Additionally, the high-dose group showed prolonged immobility time during the forced swimming test. On the balance beam, the high-dose group displayed more right turns and right-foot slips and lower time spent on the rotating bar, indicating motor defects, than did the other groups. Diffusion tensor imaging demonstrated a decreased water molecule diffusion ability in the corpus callosum in the high-dose group. LFB staining indicated microstructural differences in the white matter of animals in the high-dose group. These findings suggest that behavioural deficits in high-dose esketamine-treated rats are at least partially attributed to changes in the white matter microstructure. </div> <a href="javascript:ShowArticleAbstract(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Behaviour%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Behaviour</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Diffusion+tensor+imaging%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Diffusion tensor imaging</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neurodevelopment%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neurodevelopment</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22White+matter%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">White matter</a></li></ul> <a href="javascript:ShowArticleKeywords(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(11);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant11" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(11);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow12"> <td style="min-width: 40px; text-align: center;"> 12 </td> <td> <div id="citation12" class="article-citation"> <b>Bremner JD</b>, Williamson D, Vaccarino V. Psychometric properties of the 23-Item Clinician Administered Dissociative States Scale (CADSS) in a psychological trauma population. <em class='incite-journal-name' onclick='ShowInCiteJournal(13076);'>J Affect Disord</em> 2024;<b>364</b>:249-258. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39147159' target='_blank'>39147159</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365742' target='_blank'>PMC11365742</a> DOI: <a href='https://dx.doi.org/10.1016/j.jad.2024.08.050' target='_blank'>10.1016/j.jad.2024.08.050</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jad.2024.08.050','39147159', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(12);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(12);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(12);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(12);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jad.2024.08.050' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13076);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/jafd/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 01/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 08/11/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/17/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv12" value="10.1016/j.jad.2024.08.050" /> <div style="display: none" id="articleAbstract12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">OBJECTIVE</div><div class="abstract-content">Dissociative symptoms are both a pathological consequence of exposure to psychological trauma as well as a side effect of N-methyl-d-aspartate (NMDA) receptor antagonist medications; therefore, accurate and valid assessment of these symptoms is important. The psychometric properties of the 23-item Clinician Administered Dissociative States Scale (CADSS) have been characterized in the ketamine and esketamine literatures. Here, we examine its performance in a sample with and without posttraumatic stress disorder (PTSD) and a history of exposure to psychological trauma. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Participants with a history of psychological trauma with (N = 148) and without (N = 100) the diagnosis of PTSD and healthy participants without a psychiatric disorder or history of trauma (N = 28) were assessed with the 23-item CADSS and other psychometric and neuropsychological assessments. Analyses were performed to examine internal consistency, convergent and discriminant validity, factor structure, differential performance in populations reported to be more or less likely to report dissociative symptoms (e.g., patients with and without PTSD), and sensitivity to change resulting from exposure to trauma-related sights and sounds. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">The 23-item CADSS was found to have high internal consistency (Cronbach's alpha 0.91) and a single-factor structure. CADSS total scores in trauma-exposed participants with PTSD were higher than those in trauma-exposed participants without PTSD and non-traumatized non-PTSD participants. Finally, veterans with Iraq combat-related PTSD showed a significant increase in CADSS total score after exposure to combat-related slides and sounds. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">The 23-item CADSS, already validated as a tool to measure dissociation related to administration of NMDA receptor antagonist medication, performs in a reliable and valid manner in the assessment of dissociation in psychologically traumatized participants. </div> <a href="javascript:ShowArticleAbstract(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Assessment%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Assessment</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dissociation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dissociation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dissociative+disorders%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dissociative disorders</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Instruments%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Instruments</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Major+depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Major depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NMDA+receptor+antagonists%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">NMDA receptor antagonists</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Posttraumatic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Posttraumatic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress</a></li></ul> <a href="javascript:ShowArticleKeywords(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychometrics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychometrics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dissociative+Disorders%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dissociative Disorders/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dissociative+Disorders%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dissociative Disorders/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress+Disorders%2c+Post-Traumatic%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress Disorders, Post-Traumatic/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress+Disorders%2c+Post-Traumatic%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress Disorders, Post-Traumatic/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Stress+Disorders%2c+Post-Traumatic%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Stress Disorders, Post-Traumatic/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Reproducibility+of+Results%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Reproducibility of Results</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychological+Trauma%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychological Trauma</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychiatric+Status+Rating+Scales%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychiatric Status Rating Scales</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Neuropsychological+Tests%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Neuropsychological Tests</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li></ul> <a href="javascript:ShowArticleMeSH(12);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant12" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NCRR+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">S10 RR016917 NCRR NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22RRD+VA%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">I01 RX003418 RRD VA</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMH+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 MH056120 NIMH NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K24 HL077506 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 HL125246 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMH+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 MH120262 NIMH NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">T32 HL130025 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMH+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R21 MH080208 NIMH NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 HL068630 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIDA+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">UH3 DA048502 NIDA NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">P01 HL101398 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIDA+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">UG3 DA048502 NIDA NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NCRR+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">M01 RR000125 NCRR NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 HL109413 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22CSRD+VA%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">I01 CX002331 CSRD VA</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMH+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">T32 MH067547 NIMH NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIA+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 AG026255 NIA NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 HL136205 NHLBI NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NIMH+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">K24 MH076955 NIMH NIH HHS</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22NHLBI+NIH+HHS%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">R01 HL088726 NHLBI NIH HHS</a></li></ul> <a href="javascript:ShowArticleGrant(12);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow13"> <td style="min-width: 40px; text-align: center;"> 13 </td> <td> <div id="citation13" class="article-citation"> <b>Xiao L</b>, Zhang Z, Lu J, Liu Z, Zhang J, Kang L, Tang J, Zou X. Efficacy and safety of <span class="highlight-field">esketamine</span> combined with propofol for conscious sedation in painless colonoscopy: a prospective, randomized, double-blind controlled clinical trial. <em class='incite-journal-name' onclick='ShowInCiteJournal(3920);'>BMC Anesthesiol</em> 2024;<b>24</b>:394. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39478485' target='_blank'>39478485</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523800' target='_blank'>PMC11523800</a> DOI: <a href='https://dx.doi.org/10.1186/s12871-024-02779-0' target='_blank'>10.1186/s12871-024-02779-0</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s12871-024-02779-0','39478485', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(13);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(13);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(13);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(13);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1186/s12871-024-02779-0' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://rcastoragev2.blob.core.windows.net/fb999c489e9c8d7157bf5eb854d6e703/12871_2024_Article_2779.PMC11523800.pdf' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="openf" onclick="OpenFigures('10.1186/s12871-024-02779-0');">Figures</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3920);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 07/24/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/22/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 11/03/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv13" value="10.1186/s12871-024-02779-0" /> <div style="display: none" id="articleAbstract13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">We explored the efficacy and safety of esketamine combined with propofol for conscious sedation in painless colonoscopy. </div><div class="abstract-label">METHODS</div><div class="abstract-content">A total of 195 patients who underwent painless colonoscopy surgery were randomly divided into three groups: the propofol deep sedation group (group DS), the sufentanil combined with propofol for conscious sedation (group CS1) and the esketamine combined with propofol for conscious sedation (group CS2). The primary outcomes of this study included the incidence of hypoxemia, hypotension, hypertension, and bradycardia and excellent and good rates of anaesthesia during colonoscopy. The secondary outcomes included perioperative changes in vital signs (MAP, HR, and SpO2), anaesthesia induction time, dischargeable time, patient and endoscopist satisfaction scores, and incidence of postoperative nausea and vomiting (PONV), drowsiness, dizziness, propofol injection pain, assisted ventilation and vasoactive medications. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">The incidence of intraoperative hypoxemia in the DS group was significantly greater than that in the CS1 and CS2 groups (χ2 = 7.081, P = 0.029). The incidence of hypotension in the CS2 group was significantly lower than that in the DS and CS1 groups (χ2 = 16.278, P < 0.001). The risk of hypoxemia was 5.727 times higher in Group DS than in Group CS2 (OR 5.727; 95%CI 1.203-27.273), and the risk of hypotension was 9.864 times higher in Group DS than in Group CS2 (OR 9.864; 95%CI 2.770-35.120). The risk of hypotension in Group CS1 was 5.167 times that in Group CS2 (OR 5.167; 95%CI 1.396-19.117). The incidence of propofol injection pain, assisted ventilation, ephedrine usage and drowsiness in the DS group was significantly greater than that in the CS1 and CS2 groups (χ2 = 57.618, P < 0.001; χ2 = 9.544, P = 0.008; χ2 = 14.820, P = 0.001; χ2 = 37.257, P < 0.001). The incidence of dizziness during recovery in the CS1 group was significantly greater than that in the DS and CS2 groups (χ2 = 6.594, P = 0.037). The dischargeable time in the DS group was significantly greater than that in the CS1 and CS2 groups (F = 53.039, P < 0.001). The satisfaction scores of the endoscopist and patients in the DS group were significantly lower than those in the CS1 and CS2 groups (F = 17.390, P < 0.001; F = 19.282; P < 0.001). </div><div class="abstract-label">CONCLUSIONS</div><div class="abstract-content">In conclusion, esketamine combined with propofol for conscious sedation can be safely and effectively used for painless colonoscopy and has fewer complications.It is recommended for painless colonoscopy. </div> <a href="javascript:ShowArticleAbstract(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Conscious+sedation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Conscious sedation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Deep+sedation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Deep sedation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Efficacy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Efficacy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Painless+colonoscopy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Painless colonoscopy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Safety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Safety</a></li></ul> <a href="javascript:ShowArticleKeywords(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Double-Blind+Method%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Double-Blind Method</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Conscious+Sedation%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Conscious Sedation/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Colonoscopy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Colonoscopy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hypnotics+and+Sedatives%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hypnotics and Sedatives/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sufentanil%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sufentanil/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+Nausea+and+Vomiting%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative Nausea and Vomiting/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug+Therapy%2c+Combination%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug Therapy, Combination</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li></ul> <a href="javascript:ShowArticleMeSH(13);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant13" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+of+Science+and+Technology+of+Hunan+Province%2cChina%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">2021SK4047 Department of Science and Technology of Hunan Province,China</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Department+Science+and+Technology+of+Huaihua%2cChina%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">2022R2203 Department Science and Technology of Huaihua,China</a></li></ul> <a href="javascript:ShowArticleGrant(13);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow14"> <td style="min-width: 40px; text-align: center;"> 14 </td> <td> <div id="citation14" class="article-citation"> <b>da Costa Gonçalves KT</b>, de Tavares VDO, de Morais Barros ML, de Brito AJC, Cavalcanti-Ribeiro P, Palhano-Fontes F, Falchi-Carvalho M, Arcoverde E, Dos Santos RG, Hallak JEC, de Araujo DB, Galvão-Coelho NL. Ketamine-induced altered states of consciousness: a systematic review of implications for therapeutic outcomes in psychiatric practices. <em class='incite-journal-name' onclick='ShowInCiteJournal(8720);'>Eur Arch Psychiatry Clin Neurosci</em> 2024:10.1007/s00406-024-01925-6. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39467856' target='_blank'>39467856</a> DOI: <a href='https://dx.doi.org/10.1007/s00406-024-01925-6' target='_blank'>10.1007/s00406-024-01925-6</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s00406-024-01925-6','39467856', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(14);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(14);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleGrant(14);" target='_self'>Grants</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s00406-024-01925-6' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8720);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/eapc/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 05/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/02/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/30/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv14" value="10.1007/s00406-024-01925-6" /> <div style="display: none" id="articleAbstract14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">This systematic review aims to elucidate the nexus between ketamine's psychoactive properties and its efficacy in treating a broad spectrum of psychiatric disorders. We searched three databases and used citation tracking to include 29 studies. Predominantly, mood disorders, including bipolar disorder (BD) and major depressive disorder (MDD) (MDD + BD: + n = 25 studies), a large part of them involve treatment-resistant patients (n = 14 studies), substance use disorder (SUD, n = 3 studies), and social anxiety disorder (SAD, n = 1 study). From all included studies (n = 29), 15 (51.72%) of them identified a positive relation between ketamine-induced altered states of consciousness and clinical outcomes, while 13 studies (44.83%) showed no linkage between them, and one study (3.45%) delineated a negative association. Focusing solely on intravenous (IV) ketamine infusions (n = 25), 14 studies (56%) reported a positive modulation of ketamine's psychoactive effects and therapeutic benefits, whereas 10 studies (40%) confirmed no relationship, and one study (4%) showed a negative association. The single study (33.34%) involving subcutaneous ketamine and all three studies (66.6%) intranasal administration did not demonstrate a significant interaction between ketamine's psychoactive effects and therapeutic response. All three SUD studies reported a positive correlation between ketamine's psychoactive effects and therapeutic response. In contrast, the single SAD study did not find a relationship between these parameters. For studies involving mood disorders (n = 25), 12 studies (48%) reported a positive relationship between psychoactive effects and therapeutic response. Others 12 studies (48%) identified a null relationship, and one study (4%) found a significant negative association. Although we have found a larger association than previous studies between ketamine's psychoactive properties and its efficacy in treating a broad spectrum of psychiatric disorders, its topic remains indeterminate, mainly due to the high heterogeneity. </div> <a href="javascript:ShowArticleAbstract(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Altered+states+of+consciousness+hallucinogen%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Altered states of consciousness hallucinogen</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anxiety%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anxiety</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bipolar+disorder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bipolar disorder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dissociation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dissociation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Mystical+experiences%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Mystical experiences</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychedelic%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychedelic</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychotomimetic+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychotomimetic effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Substance+dependence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Substance dependence</a></li></ul> <a href="javascript:ShowArticleKeywords(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(14);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant14" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22fund%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Coordena%c3%a7%c3%a3o+de+Aperfei%c3%a7oamento+de+Pessoal+de+N%c3%advel+Superior%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">88887.597821/2021-00 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior</a></li></ul> <a href="javascript:ShowArticleGrant(14);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow15"> <td style="min-width: 40px; text-align: center;"> 15 </td> <td> <div id="citation15" class="article-citation"> <b>Wan JX</b>, Zeng SS, Wu ZQ, Wang Y, Wang N, Wang FJ. Effect of different doses of <span class="highlight-field">esketamine</span> on the median effective concentration of propofol for inhibiting body movement during hysteroscopy. <em class='incite-journal-name' onclick='ShowInCiteJournal(20954);'>Sci Rep</em> 2024;<b>14</b>:25153. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39448738' target='_blank'>39448738</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11502770' target='_blank'>PMC11502770</a> DOI: <a href='https://dx.doi.org/10.1038/s41598-024-75902-3' target='_blank'>10.1038/s41598-024-75902-3</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1038/s41598-024-75902-3','39448738', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(15);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(15);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(15);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1038/s41598-024-75902-3' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(20954);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/09/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/26/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv15" value="10.1038/s41598-024-75902-3" /> <div style="display: none" id="articleAbstract15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The objective of this study is to investigate the effects of various doses of esketamine on the median effective concentration (EC50) of propofol required for inhibiting body movement during hysteroscopy. Additionally, this research aims to explore the pharmacodynamic interactions between esketamine and propofol. Prospective, double-blind, up-down sequential allocation study. Operating room, post-anesthesia care unit (PACU), and general ward. A total of 90 patients were allocated into three groups in a randomized, double-blinded manner as follows: 0.1 mg/kg esketamine combined with propofol intravenous injection (EP0.1) group, 0.2 mg/kg esketamine combined with propofol intravenous injection (EP0.2) group, 0.3 mg/kg esketamine combined with propofol of intravenous injection (EP0.3) group. For the initial patient in each group, the starting effector target concentration of propofol was set at 4 µg/ml. Each patient received an initial intravenous injection of 0.04 mg/kg midazolam, followed by the administration of the appropriate dose of esketamine. Ten seconds after the esketamine injection, propofol was administered intravenously to achieve the target concentration. In accordance with the sequential method principle, the concentration of propofol for the subsequent patient was adjusted based on the response of the previous patient. Effective inhibition of body movement was defined as the absence of any involuntary body movements throughout the entire surgical process. If the previous patient exhibited body movements, the propofol concentration for the next patient was increased by 0.5 µg/ml; conversely, if no movements were observed, it was decreased by 0.5 µg/ml. The up-down sequential allocation method and probit regression were used to calculate the EC50 of propofol. Hospital Anxiety and Depression Scale-Anxiety (HADS-A) and Depression (HADS-D) score, adverse events, hemodynamic changes, demographic data and clinical characteristics. The EC50 of propofol was 3.849 μg/ml (95% CI: 3.419-4.281) in the EP0.1 group, 3.641 μg/ml (95% CI: 2.807-4.200) in the EP0.2 group, and 3.417 μg/ml (95% CI: 2.845-3.852) in the EP0.3 group. These findings suggest that esketamine can dose-dependently reduce the EC50 of propofol. Esketamine can dose-dependently reduce the EC50 of propofol in hysteroscopy, while concurrently lowering patients' HADS-A and HADS-D scores 24 h post-operation. It is concluded that the optimal dose of esketamine, when combined with propofol for hysteroscopy, is 0.3 mg/kg. </div> <a href="javascript:ShowArticleAbstract(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthetics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthetics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22EC50%5cn+++++++++++++++++++++%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">EC50 </a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hysteroscopy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hysteroscopy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol</a></li></ul> <a href="javascript:ShowArticleKeywords(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Propofol%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Propofol/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Hysteroscopy%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Hysteroscopy/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Double-Blind+Method%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Double-Blind Method</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthetics%2c+Intravenous%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthetics, Intravenous/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Movement%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Movement/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Dose-Response+Relationship%2c+Drug%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Dose-Response Relationship, Drug</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug+Interactions%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug Interactions</a></li></ul> <a href="javascript:ShowArticleMeSH(15);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant15" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(15);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow16"> <td style="min-width: 40px; text-align: center;"> 16 </td> <td> <div id="citation16" class="article-citation"> <b>Zhou L</b>, Lv L, Wu R, Mang W, Hu L. Improvement in pain by using lidocaine combined with <span class="highlight-field">esketamine</span> in elderly patients receiving local anaesthesia for percutaneous kyphoplasty: a randomized controlled study. <em class='incite-journal-name' onclick='ShowInCiteJournal(3920);'>BMC Anesthesiol</em> 2024;<b>24</b>:384. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39443898' target='_blank'>39443898</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11498954' target='_blank'>PMC11498954</a> DOI: <a href='https://dx.doi.org/10.1186/s12871-024-02768-3' target='_blank'>10.1186/s12871-024-02768-3</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1186/s12871-024-02768-3','39443898', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(16);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(16);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(16);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1186/s12871-024-02768-3' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3920);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 04/07/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 10/14/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/25/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv16" value="10.1186/s12871-024-02768-3" /> <div style="display: none" id="articleAbstract16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Elderly patients often experience severe pain during percutaneous kyphoplasty under local anaesthesia. The aim of this work was to evaluate the effect of lidocaine combined with esketamine on pain improvement in elderly patients receiving local anaesthesia via percutaneous kyphoplasty. </div><div class="abstract-label">METHODS</div><div class="abstract-content">This prospective, randomized comparative trial was conducted on 66 elderly patients, aged 60-80 years, with an American Society of Anaesthesiologists (ASA) grade of I-III, I‒III and a BMI of 18.5-25 kg/m2, who underwent single-level lumbar percutaneous kyphoplasty under local anaesthesia. Patients were divided into two equal groups (33 per group). Group LE received 200 mg of 1% lidocaine and 25 mg of esketamine (total volume of 20 ml), and Group L received 200 mg of 1% lidocaine (total volume of 20 ml). Patient characteristics, surgery, VAS scores, MAP, HR, MOAA/S scores, patient satisfaction and related adverse reactions were compared for the groups. The VAS scores during and after surgery were considered the primary outcome. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">There were statistically significant differences in the VAS score between the two groups at the following time points: channel establishment by the puncture needle, balloon dilation, bone cement injection and postoperative period (P < 0.05). The VAS score decreased in the LE group, but the MAP and HR were more stable, and the difference was statistically significant (P < 0.05). The difference in the MOAA/S score between the two groups was statistically significant (P < 0.05), and the MOAA/S score in the LE group decreased. The patient satisfaction level in the LE group was 100% and 48.48% in the L group (P < 0.05). There were no related complications or adverse reactions in either group. </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">The application of lidocaine combined with esketamine in local episcopal percutaneous vertebral kyphoplasty in elderly patients not only provides an effective analgesic effect but also improves surgical safety and patient comfort, which has important clinical value in promoting the optimization of surgical anaesthesia management in elderly patients. </div><div class="abstract-label">TRIAL REGISTRATION</div><div class="abstract-content">The study was registered at Chictr.org.cn with the number ChiCTR2400083466 on 06/12/2023. </div> <a href="javascript:ShowArticleAbstract(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adjuvants%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adjuvants</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Local+anaesthesia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Local anaesthesia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Old+age%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Old age</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Percutaneous+kyphoplasty%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Percutaneous kyphoplasty</a></li></ul> <a href="javascript:ShowArticleKeywords(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Kyphoplasty%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Kyphoplasty/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Lidocaine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Lidocaine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Prospective+Studies%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Prospective Studies</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthetics%2c+Local%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthetics, Local/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%2c+80+and+over%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged, 80 and over</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthesia%2c+Local%2fmethods%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthesia, Local/methods</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pain%2c+Postoperative%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pain, Postoperative/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pain%2c+Postoperative%2fprevention+%26amp%3b+control%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pain, Postoperative/prevention & control</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug+Therapy%2c+Combination%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug Therapy, Combination</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pain+Measurement%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pain Measurement</a></li></ul> <a href="javascript:ShowArticleMeSH(16);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant16" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(16);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow17"> <td style="min-width: 40px; text-align: center;"> 17 </td> <td> <div id="citation17" class="article-citation"> <b>Kwan ATH</b>, Rosenblat JD, Mansur RB, Rhee TG, Teopiz K, Le GH, Wong S, Cao B, Ho R, McIntyre RS. A replication study using the World Health Organization pharmacovigilance database (VigiBase®) to evaluate whether an association between ketamine and <span class="highlight-field">esketamine</span> and alcohol and substance misuse exists. <em class='incite-journal-name' onclick='ShowInCiteJournal(13076);'>J Affect Disord</em> 2024;<b>363</b>:589-594. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39029700' target='_blank'>39029700</a> DOI: <a href='https://dx.doi.org/10.1016/j.jad.2024.07.128' target='_blank'>10.1016/j.jad.2024.07.128</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.jad.2024.07.128','39029700', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(17);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(17);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(17);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.jad.2024.07.128' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(13076);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/jafd/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/06/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 07/01/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/16/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/21/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv17" value="10.1016/j.jad.2024.07.128" /> <div style="display: none" id="articleAbstract17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND AND OBJECTIVES</div><div class="abstract-content">Ketamine and esketamine are increasingly prescribed in the treatment of resistant mood disorders and persons at risk of suicide. Ketamine is a drug of misuse with increasing non-therapeutic use in the general population. Herein, our aim was to determine whether ketamine and/or esketamine are disproportionately associated with reports of substance and/or alcohol misuse. </div><div class="abstract-label">METHODS</div><div class="abstract-content">Replicating a similar analysis recently conducted using the Food and Drug Administration Adverse Event Reporting System (FAERS) database, we identified cases of "alcohol problem, alcoholism, alcohol abuse, substance dependence, substance use disorder (SUD), substance abuse, drug dependence, drug use disorder and drug abuse" in association with ketamine and esketamine reported to the World Health Organization Pharmacovigilance Database (WHO VigiBase). We searched the database from inception to January 2024. The reporting odds ratio (ROR) of each of the aforementioned parameters was calculated; acetaminophen was used as the control. The numerator of the equation represents the number of cases (n) and the denominator represents the total cases of psychiatric disorders (N). Significance was obtained when the lower limit of the 95 % confidence (CI) > 1.0. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">The RORs for ketamine was increased for most parameters (i.e., alcohol abuse (3.24), substance dependence (12.48), substance use disorder (170.44), substance abuse (2.94), drug dependence (2.88), drug use disorder (11.54) and drug abuse (2.85), respectively). With respect to esketamine, the RORs were observed to be different from ketamine insofar as we observed a reduction in the RORs for three parameters (i.e., substance abuse (0.41), drug dependence (0.083) and drug abuse (0.052), respectively). The IC025 values were significant for ketamine in cases of alcohol abuse (0.35), substance dependence (0.50), substance use disorder (2.77), substance abuse (0.83), drug dependence (0.97), drug use disorder (1.95) and drug abuse (0.94). Additionally, oxycontin showed significant IC025 values for substance use disorder (0.0014), substance abuse (0.042), and drug dependence (0.17). </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Esketamine was not associated with an increased ROR for any parameter of alcohol and/or substance use disorder. Mixed results were observed with ketamine with some RORs increased and others decreased. Estimating RORs using a pharmacovigilance database does not establish causation in the case of elevated RORs and cannot be assumed to be a therapeutic effect when lower RORs were observed. </div> <a href="javascript:ShowArticleAbstract(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alcohol+use+disorder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alcohol use disorder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Amphetamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Amphetamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Opioid%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Opioid</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pharmacovigilance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pharmacovigilance</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Substance+use+disorder+(SUD)%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Substance use disorder (SUD)</a></li></ul> <a href="javascript:ShowArticleKeywords(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Substance-Related+Disorders%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Substance-Related Disorders/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Pharmacovigilance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Pharmacovigilance</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22World+Health+Organization%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">World Health Organization</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Databases%2c+Factual%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Databases, Factual</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Alcoholism%2fepidemiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Alcoholism/epidemiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adverse+Drug+Reaction+Reporting+Systems%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adverse Drug Reaction Reporting Systems/statistics & numerical data</a></li></ul> <a href="javascript:ShowArticleMeSH(17);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant17" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(17);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow18"> <td style="min-width: 40px; text-align: center;"> 18 </td> <td> <div id="citation18" class="article-citation"> <b>Li J</b>, Ma L, Sun H, Li M, Cao Y, Peng Y, Xu J. Efficacy of racemic ketamine or <span class="highlight-field">esketamine</span> monotherapy for reducing suicidal ideation in uni- or bipolar depression: a systematic review and meta-analysis. <em class='incite-journal-name' onclick='ShowInCiteJournal(8720);'>Eur Arch Psychiatry Clin Neurosci</em> 2024:10.1007/s00406-024-01920-x. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39382685' target='_blank'>39382685</a> DOI: <a href='https://dx.doi.org/10.1007/s00406-024-01920-x' target='_blank'>10.1007/s00406-024-01920-x</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1007/s00406-024-01920-x','39382685', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(18);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(18);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1007/s00406-024-01920-x' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(8720);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.editorialmanager.com/eapc/default1.aspx' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/26/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 09/20/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/10/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv18" value="10.1007/s00406-024-01920-x" /> <div style="display: none" id="articleAbstract18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The current systematic review and meta-analysis examined the effect of racemic ketamine or esketamine on suicidal ideation in individuals with uni- or bipolar depression. We searched the MEDLINE, Embase, Central, PsycINFO, and Web of Science databases to identify randomized controlled trials that examined the effect of racemic ketamine or esketamine monotherapy on suicidal ideation (SI) in individuals with uni- or bipolar depression. The two monotherapies were compared; the primary outcome was the rate of remission of SI, and the secondary outcome was the SI score. The risk ratio was used as an effect size measure for binary variables, while the standardized mean difference was used as an effect size measure for continuous variables. Our meta-analysis included 13 randomized controlled trials involving 1,1109 individuals with uni- or bipolar depression. Patients receiving racemic ketamine monotherapy had a significantly higher acute SI remission rate than those receiving placebo or midazolam (RR = 2.06, 95% CI 1.47 to 2.91, P < 0.0001). Racemic ketamine also led to significantly lower SI scores than placebo or midazolam (SMD = -0.36, 95% CI -0.71 to -0.01, P = 0.04). The evidence for the treatment of SI with esketamine was inconsistent. The pooled effect sizes for long-term anti-SI effects did not reveal significant differences between therapies. Our study indicated the efficacy of racemic ketamine monotherapy for rapidly and transiently reducing SI in individuals with uni- or bipolar depression, but the efficacy of racemic ketamine monotherapy against long-term suicidal ideation remains unclear. There is not -sufficient evidence to support the anti-suicidal effects of esketamine monotherapy.Protocol registration: Prospero registration number: CRD42023434380. </div> <a href="javascript:ShowArticleAbstract(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Bipolar+disorder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Bipolar disorder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Major+depressive+disorder%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Major depressive disorder</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Meta-analysis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Meta-analysis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Suicidal+ideation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Suicidal ideation</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Systematic+review%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Systematic review</a></li></ul> <a href="javascript:ShowArticleKeywords(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(18);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant18" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(18);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow19"> <td style="min-width: 40px; text-align: center;"> 19 </td> <td> <div id="citation19" class="article-citation"> <b>Fotiadis P</b>, Tsalkitzi E, Dimellis D, Rantis K, Tsimpiris A, Pagkalos G. Results of <span class="highlight-field">esketamine</span> administration in a Greek population; A case series. <em>PSYCHIATRIKE = PSYCHIATRIKI</em> 2024;<b>35</b>:243-250. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38814267' target='_blank'>38814267</a> DOI: <a href='https://dx.doi.org/10.22365/jpsych.2024.006' target='_blank'>10.22365/jpsych.2024.006</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.22365/jpsych.2024.006','38814267', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(19);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(19);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(19);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.22365/jpsych.2024.006' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 05/31/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv19" value="10.22365/jpsych.2024.006" /> <div style="display: none" id="articleAbstract19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Esketamine is a non-selective, competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor in the brain. Through NMDA receptor antagonism, esketamine causes a transient increase in glutamate release, leading to increases in neurotrophic signaling and restoration of synaptic function in brain regions involved in mood regulation and emotional behavior. Several randomized clinical trials have shown its effectiveness in reducing the symptoms of depression in some people, despite its short-term side effects that include mainly disorientation, dizziness, nausea, and increased blood pressure. In 2019, the United States Food and Drug Administration (FDA) as well as the European Medicines Agency approved the use of esketamine nasal spray in combination with an oral antidepressant for treatment-resistant depression in adults. Our study aimed to evaluate the effectiveness of this new therapeutic proposal in a case series of five Greek patients with treatment- resistant depression. Intranasal esketamine was administered under medical supervision in combination with an oral antidepressant. Depressive symptoms were evaluated at three time points (baseline, end of treatment, and one-year post-treatment) using the Montgomery-Åsberg Depression Rating Scale (MADRS), the Patient Health Questionnaire (PHQ-9), the CGI Clinical Global Impression Scale, and the Perceived Deficits Questionnaire for Depression (PDQ-D). Possible side effects were assessed using the Richmond Suppression Agitation Scale (RASS), the Sheehan Disability Scale (SDS), the CADSS Disruptive States Scale, and a predefined list of adverse events (AEs) and serious adverse events (SAEs). Patients followed an individualized treatment plan for seven to twelve months depending on the achievement of an adequate response. Statistical analysis of the results revealed a significant improvement (p<0.05) on all scales used. All participants maintained their level of improvement at follow-up after twelve months. Adverse effects were found to be mild and tolerable. It is worth noting that significant side effects were reported only by the two patients with comorbid personality disorder. The results, despite limited to a small sample, indicate the positive effect of esketamine on the stable reduction of depressive symptoms among patients with resistant depression, even after the completion of treatment. </div> <a href="javascript:ShowArticleAbstract(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22fast-acting+antidepressant%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">fast-acting antidepressant</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22mood+disorders%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">mood disorders</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22therapeutic+intervention%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">therapeutic intervention</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22treatment-resistant+depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">treatment-resistant depression</a></li></ul> <a href="javascript:ShowArticleKeywords(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Treatment-Resistant%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Treatment-Resistant/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Administration%2c+Intranasal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Administration, Intranasal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Greece%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Greece</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antidepressive+Agents%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antidepressive Agents/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antidepressive+Agents%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antidepressive Agents/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Treatment+Outcome%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Treatment Outcome</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug+Therapy%2c+Combination%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug Therapy, Combination</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychiatric+Status+Rating+Scales%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychiatric Status Rating Scales</a></li></ul> <a href="javascript:ShowArticleMeSH(19);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant19" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(19);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow20"> <td style="min-width: 40px; text-align: center;"> 20 </td> <td> <div id="citation20" class="article-citation"> <b>Chen HZ</b>, Gao Y, Li KK, An L, Yan J, Li H, Zhang J. Effect of intraoperative injection of <span class="highlight-field">esketamine</span> on postoperative analgesia and postoperative rehabilitation after cesarean section. <em class='incite-journal-name' onclick='ShowInCiteJournal(23577);'>World J Clin Cases</em> 2024;<b>12</b>:6195-6203. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39371565' target='_blank'>39371565</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362894' target='_blank'>PMC11362894</a> DOI: <a href='https://dx.doi.org/10.12998/wjcc.v12.i28.6195' target='_blank'>10.12998/wjcc.v12.i28.6195</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.12998/wjcc.v12.i28.6195','39371565', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(20);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(20);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.wjgnet.com/2307-8960/full/v12/i28/6195.htm' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.f6publishing.com/forms/main/DownLoadFile.aspx?Type=Digital&TypeId=1&id=10.12998%2fwjcc.v12.i28.6195&FilePath=44E87A1D68BFCDDE196C122AD37454541B510F5F277371E142E546CCF925341B1267549F3F9C5082B68572549512A74727BD89D104FC34B3AC34250F39648FEA79D0FB27D7634B19' target='_blank'>Download PDF</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(23577);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://www.f6publishing.com/' target="_blank">Submit a Manuscript</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 03/04/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 06/10/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 07/23/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 08/13/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv20" value="10.12998/wjcc.v12.i28.6195" /> <div style="display: none" id="articleAbstract20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">BACKGROUND</div><div class="abstract-content">Following cesarean section, a significant number of women encounter moderate to severe pain. Inadequate management of acute pain post-cesarean section can have far-reaching implications, adversely impacting maternal emotional well-being, daily activities, breastfeeding, and neonatal care. It may also impede maternal organ function recovery, leading to escalated opioid usage, heightened risk of postpartum depression, and the development of chronic postoperative pain. Both the Chinese Enhanced Recovery After Surgery (ERAS) guidelines and the American ERAS Society guidelines consistently advocate for the adoption of multimodal analgesia protocols in post-cesarean section pain management. Esketamine, functioning as an antagonist of the N-Methyl-D-Aspartate receptor, has been validated for pain management in surgical patients and has exhibited effectiveness in depression treatment. Research has suggested that incorporating esketamine into postoperative pain management via pain pumps can lead to improvements in short-term depression and pain outcomes. This study aims to assess the efficacy and safety of administering a single dose of esketamine during cesarean section. </div><div class="abstract-label">AIM</div><div class="abstract-content">To investigate the effect of intraoperative injection of esketamine on postoperative analgesia and postoperative rehabilitation after cesarean section. </div><div class="abstract-label">METHODS</div><div class="abstract-content">A total of 315 women undergoing elective cesarean section under combined spinal-epidural anesthesia were randomized into three groups: low-dose esketamine (0.15 mg/kg), high-dose esketamine (0.25 mg/kg), and control (saline). Postoperative Visual Analog Scale (VAS) scores were recorded at 6 hours, 12 hours, 24 hours, and 48 hours. Edinburgh Postnatal Depression Scale (EPDS) scores were noted on 2 days, 7 days and 42 days. Ramsay sedation scores were assessed at specified intervals post-injection. Postoperative adverse reactions were also recorded. </div><div class="abstract-label">RESULTS</div><div class="abstract-content">Low-dose group and high-dose group compared to control group, had significantly lower postoperative VAS pain scores at 6 hours 12 hours, and 24 hours (P < 0.05), with reduced analgesic usage (P < 0.05). EPDS scores and postpartum depression rates were significantly lower on 2 days and 7 days (P < 0.05). No significant differences in first exhaust and defecation times were observed (P > 0.05), but ambulation times were shorter (P < 0.05). Ramsay scores were higher at 5 minutes, 15 minutes, and upon room exit (P < 0.05). Low-dose group and high-dose group had higher incidences of hallucination, lethargy, and diplopia within 2 hours (P < 0.05), and with low-dose group had lower incidences of hallucination, lethargy, and diplopia than high-dose group (P < 0.05). </div><div class="abstract-label">CONCLUSION</div><div class="abstract-content">Esketamine enhances analgesia and postpartum recovery; a 0.15 mg/kg dose is optimal for cesarean sections, balancing efficacy with minimized adverse effects. </div> <a href="javascript:ShowArticleAbstract(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Cesarean+section%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Cesarean section</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Maternity%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Maternity</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postoperative+analgesia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postoperative analgesia</a></li></ul> <a href="javascript:ShowArticleKeywords(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <a href="javascript:ShowArticleMeSH(20);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant20" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(20);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow21"> <td style="min-width: 40px; text-align: center;"> 21 </td> <td> <div id="citation21" class="article-citation"> <b>Ochigbo EB</b>, Beinfeld MT, Chambers JD. Balancing Evidence and Need: Variation in US Commercial Payer Coverage of <span class="highlight-field">Esketamine</span>. <em class='incite-journal-name' onclick='ShowInCiteJournal(6708);'>Clin Ther</em> 2024;<b>46</b>:808-811. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39039006' target='_blank'>39039006</a> DOI: <a href='https://dx.doi.org/10.1016/j.clinthera.2024.06.017' target='_blank'>10.1016/j.clinthera.2024.06.017</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.clinthera.2024.06.017','39039006', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(21);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(21);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(21);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.clinthera.2024.06.017' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(6708);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 10/03/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 06/19/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/25/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/24/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv21" value="10.1016/j.clinthera.2024.06.017" /> <div style="display: none" id="articleAbstract21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">PURPOSE</div><div class="abstract-content">Variations in US commercial health plan coverage policies affect how patients access medications. Plans may vary in treatment access criteria, line of therapy, and prescriber requirements. In this study, we examined coverage of esketamine hydrochloride (Spravato) for major depressive disorder (MDD) and treatment-resistant depression (TRD) to answer the following question: how do US commercial health plans cover esketamine, and how do they guide prompt patient access to the drug? </div><div class="abstract-label">METHODS</div><div class="abstract-content">We used information from the Tufts Medical Center Specialty Drug Evidence and Coverage database, which includes coverage policies issued by 18 large commercial health plans in the United States. Esketamine coverage policies for MDD and TRD active in December 2022 were collated and analyzed. We compared coverage policies according to step therapy protocols, patient subgroup restrictions, and prescriber requirement criteria, evaluating patient access using the number of restrictions and proportion of plans including each criterion. </div><div class="abstract-label">FINDINGS</div><div class="abstract-content">Plans more often imposed step therapy requirements for access to esketamine for TRD than for MDD, with line of treatment of ≤9 steps for MDD compared with 1 to 5 steps for TRD. Plans also varied with respect to the therapies they required patients to first try and experience treatment failure before granting access to esketamine for both indications. Clinical coverage requirements varied in thresholds and rating scales used to assess severity of depressive symptoms. </div><div class="abstract-label">IMPLICATIONS</div><div class="abstract-content">Plans vary in terms of line of therapy and clinical coverage requirements for access to esketamine. Variation in health plan coverage policies may result in inequitable access and added complexity for patients and clinicians navigating care, which may delay access to urgent treatment. </div><div class="abstract-label">CLINICALTRIALS</div><div class="abstract-label">GOV IDENTIFIERS</div><div class="abstract-content">Not applicable. </div> <a href="javascript:ShowArticleAbstract(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Coverage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Coverage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Evidence%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Evidence</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insurance%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insurance</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Payers%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Payers</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Variation%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Variation</a></li></ul> <a href="javascript:ShowArticleKeywords(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22United+States%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">United States</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Treatment-Resistant%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Treatment-Resistant/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Treatment-Resistant%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Treatment-Resistant/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Insurance+Coverage%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Insurance Coverage/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antidepressive+Agents%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antidepressive Agents/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Antidepressive+Agents%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Antidepressive Agents/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Major%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Major/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Major%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Major/economics</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Health+Services+Accessibility%2feconomics%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Health Services Accessibility/economics</a></li></ul> <a href="javascript:ShowArticleMeSH(21);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant21" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(21);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow22"> <td style="min-width: 40px; text-align: center;"> 22 </td> <td> <div id="citation22" class="article-citation"> <b>Liu P</b>, Zhang K, Tong C, Liu T, Zheng J. Progesterone alleviates <span class="highlight-field">esketamine</span>-induced hypomyelination via PI3K/Akt signaling pathway in the developing rat brain. <em class='incite-journal-name' onclick='ShowInCiteJournal(3716);'>Biotechnol Genet Eng Rev</em> 2024;<b>40</b>:1202-1217. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/36946765' target='_blank'>36946765</a> DOI: <a href='https://dx.doi.org/10.1080/02648725.2023.2193058' target='_blank'>10.1080/02648725.2023.2193058</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1080/02648725.2023.2193058','36946765', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(22);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(22);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(22);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1080/02648725.2023.2193058' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(3716);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 02/10/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 03/14/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 03/23/2023]</span></span> </div> <input type="hidden" name="doiv" id="doiv22" value="10.1080/02648725.2023.2193058" /> <div style="display: none" id="articleAbstract22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">The neurodevelopmental toxicity of anesthetics has been confirmed repeatedly, and esketamine is now widely used in pediatric surgeries. Oligodendrocyte precursor cells (OPCs) evolved into mature oligodendrocytes (OLs) and formed myeline sheath during the early brain development. In this study, we investigated whether esketamine exposure interrupted development of OPCs and induced hypomyelination in rats. Further we explored the roles of PI3K/Akt phosphorylation in OPCs development and myelination. Sprague Dawley rats with different ages (postnatal day (P) 1, 3, 7 and 12) were exposed to 40mg/kg esketamine. Progesterone treatment was given (16 mg/kg per day for 3 days) 24 h after esketamine exposure via the intraperitoneal route. Corpus callosum tissues were collected at P8 or P14 for western blot and immunofluorescence analyses. Esketamine exposure at P7 and P12 significantly reduced myelin basic protein (MBP) expression and CC1+ OLs number in corpus callosum. Esketamine exposure at P7 not only aggravated the mature OLs apoptosis, also decreased the OPCs proliferation and differentiation, which was related with dephosphorylation of PI3K/Akt. Progesterone was able to promote OPCs differentiation and ameliorate esketamine-induced hypomyelination by enhancing PI3K/Akt phosphorylation. Stage-dependent abnormality of OPCs/OLs after esketamine leads to the esketamine-induced hypomyelination. Esketamine interrupted OPCs evolution via PI3K/Akt signaling pathway, which can be ameliorated by progesterone. </div> <a href="javascript:ShowArticleAbstract(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22hypomyelination%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">hypomyelination</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22myelin+basic+protein%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">myelin basic protein</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22oligodendrocytes%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">oligodendrocytes</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22progesterone%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">progesterone</a></li></ul> <a href="javascript:ShowArticleKeywords(22);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh22" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Animals%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Animals</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Progesterone%2fpharmacology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Progesterone/pharmacology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Progesterone%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Progesterone/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Signal+Transduction%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Signal Transduction/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Proto-Oncogene+Proteins+c-akt%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Proto-Oncogene Proteins c-akt/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Phosphatidylinositol+3-Kinases%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Phosphatidylinositol 3-Kinases/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rats%2c+Sprague-Dawley%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rats, Sprague-Dawley</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fmetabolism%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/metabolism</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fdrug+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/drug effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fgrowth+%26amp%3b+development%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/growth & development</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Brain%2fpathology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Brain/pathology</a></li><li><a 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<b>Tang J</b>, Munoz T, Jolivet I, Chappell K, Choucha W, Colle R, Verstuyft C, de Lepinau J, Corruble E, Gasnier M. Intra-nasal <span class="highlight-field">esketamine</span> induced psychotic disorder in a post COVID-19 major depressive episode: A case report. <em>L'ENCEPHALE</em> 2024;<b>50</b>:583-584. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/38971648' target='_blank'>38971648</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169572' target='_blank'>PMC10169572</a> DOI: <a href='https://dx.doi.org/10.1016/j.encep.2023.05.001' target='_blank'>10.1016/j.encep.2023.05.001</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.1016/j.encep.2023.05.001','38971648', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(23);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(23);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.1016/j.encep.2023.05.001' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 11/16/2022]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 04/26/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 05/04/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 07/08/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv23" value="10.1016/j.encep.2023.05.001" /> <div style="display: none" id="articleAbstract23" class="article-abstract"> <b style="display: block; 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padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadverse+effects%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/adverse effects</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2fadministration+%26amp%3b+dosage%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/administration & dosage</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Major%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Major/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Depressive+Disorder%2c+Major%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Depressive Disorder, Major/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22COVID-19%2fcomplications%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">COVID-19/complications</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Administration%2c+Intranasal%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Administration, Intranasal</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychoses%2c+Substance-Induced%2fetiology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychoses, Substance-Induced/etiology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychoses%2c+Substance-Induced%2fdiagnosis%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychoses, Substance-Induced/diagnosis</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychoses%2c+Substance-Induced%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychoses, Substance-Induced/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychotic+Disorders%2fpsychology%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychotic Disorders/psychology</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychotic+Disorders%2fdrug+therapy%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychotic Disorders/drug therapy</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22SARS-CoV-2%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">SARS-CoV-2</a></li></ul> <a href="javascript:ShowArticleMeSH(23);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant23" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(23);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow24"> <td style="min-width: 40px; text-align: center;"> 24 </td> <td> <div id="citation24" class="article-citation"> <b>Paiva TJ</b>, Hallowell BD, Fischer S, Bratberg J, St John K, Nitenson AZ, Wightman RS. Statewide Ketamine and <span class="highlight-field">Esketamine</span> Prescribing Trends in Rhode Island, 2017-2023. <em>RHODE ISLAND MEDICAL JOURNAL (2013)</em> 2024;<b>107</b>:26-32. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39331010' target='_blank'>39331010</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('pmid/39331010','39331010', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(24);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(24);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleMeSH(24);" target='_self'>MESH Headings</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 09/28/2024]</span></span> </div> <input type="hidden" name="doiv" id="doiv24" value="pmid/39331010" /> <div style="display: none" id="articleAbstract24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-content">Ketamine is a versatile anesthetic that has been widely used off-label to treat a variety of indications. Esketamine, a derivative of ketamine, is FDA-approved to treat treatment-resistant depression. This report compares statewide prescription ketamine and esketamine trends. Using PDMP data from 2017-2023, prescription and prescriber characteristics, and patient demographics were compared between esketamine and ketamine prescriptions. During this time, ketamine prescriptions, patients, and providers rose 55.8%, 30.6%, and 2.8% since 2017. Esketamine prescriptions increased 1289.4% since 2019. In 2023, ketamine prescriptions were primarily in powder form (98.7%) and paid for out-of-pocket (83.9%), whereas esketamine prescriptions were primarily paid for by insurance (80.2%). The proportion of ketamine prescribed in RI but dispensed out-of-state have increased 22% since 2022 (18% of total dispensations). As more people seek treatment for mental health disorders, ketamine and esketamine prescriptions continue to rise. Understanding ketamine and esketamine use can help mitigate associated adverse events. </div> <a href="javascript:ShowArticleAbstract(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Off-label%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Off-label</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Psychiatric+Disorders%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Psychiatric Disorders</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rhode+Island%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rhode Island</a></li></ul> <a href="javascript:ShowArticleKeywords(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleMesh24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">MESH Headings</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Ketamine%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Ketamine/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Humans%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Humans</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Rhode+Island%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Rhode Island</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Male%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Male</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Female%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Female</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Middle+Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Middle Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Practice+Patterns%2c+Physicians%27%2ftrends%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Practice Patterns, Physicians'/trends</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Practice+Patterns%2c+Physicians%27%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Practice Patterns, Physicians'/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Adolescent%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Adolescent</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Young+Adult%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Young Adult</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Drug+Prescriptions%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Drug Prescriptions/statistics & numerical data</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Aged%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Aged</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Anesthetics%2c+Dissociative%2ftherapeutic+use%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Anesthetics, Dissociative/therapeutic use</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Child%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Child</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22mesh%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Off-Label+Use%2fstatistics+%26amp%3b+numerical+data%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Off-Label Use/statistics & numerical data</a></li></ul> <a href="javascript:ShowArticleMeSH(24);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleGrant24" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Grants</b> <a href="javascript:ShowArticleGrant(24);" target="_self" style="float: right;">Collapse</a> </div> </td> </tr> <tr id="articlerow25"> <td style="min-width: 40px; text-align: center;"> 25 </td> <td> <div id="citation25" class="article-citation"> <b>Jiang H</b>, Quan S, Su Y, Li J, Zhang X. Analysis of clinical application effects of <span class="highlight-field">Esketamine</span> combining Sufentanil in labor analgesia and their impacts on postpartum depression. <em class='incite-journal-name' onclick='ShowInCiteJournal(18714);'>Pak J Med Sci</em> 2024;<b>40</b>:1914-1918. [PMID: <a href='http://www.ncbi.nlm.nih.gov/pubmed/39416617' target='_blank'>39416617</a> PMCID: <a href='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11476173' target='_blank'>PMC11476173</a> DOI: <a href='https://dx.doi.org/10.12669/pjms.40.9.8689' target='_blank'>10.12669/pjms.40.9.8689</a>]<span class="ref-count-nolink"> <span class="ref-count-sep">[</span>Citation(s) in <i>RCA</i>: 0<span class='ref-count-sep'>]</span></span><span class="ref-count-nolink"> <span class='ref-count-sep'>[</span>Impact Index Per Article: 0<span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' name="sra" onclick="ShowRefArticle('10.12669/pjms.40.9.8689','39416617', 'Esketamine')">Reference Citation Analysis</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleAbstract(25);" name="saa" target='_self'>Abstract</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowArticleKeywords(25);" target='_self'>Key Words</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='http://dx.doi.org/10.12669/pjms.40.9.8689' target='_blank'>Track Full Text</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='javascript:void(0);' onclick="ShowInCiteJournal(18714);" name="showj" target='_self'>Journal Information</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/subscribe' target="_blank">Subscribe</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[</span><a href='https://referencecitationanalysis.com/ScholarRegist' target="_blank">Scholar Register</a><span class='ref-count-sep'>]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Received: 06/23/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Revised: 08/31/2023]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Accepted: 06/30/2024]</span></span><span class="ref-count"> <span class='ref-count-sep'>[Indexed: 10/19/2024]</span></span><span class="ref-count">  Open</span> </div> <input type="hidden" name="doiv" id="doiv25" value="10.12669/pjms.40.9.8689" /> <div style="display: none" id="articleAbstract25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Abstract</b> <div class="abstract-label">Objective</div><div class="abstract-content">To evaluate the clinical effects of Esketamine combining Sufentanil in labor analgesia and their impacts on postpartum depression. </div><div class="abstract-label">Methods</div><div class="abstract-content">This was a retrospective study. One hundred and fifty primiparae with spontaneous labor were selected at SSL Central Hospital of Dongguan City from July 10, 2021 to May 10, 2022 as the research objects and randomly divided into two groups (each n=75). While the control group underwent epidural infusion of Sufentanil for analgesia, the study group was administered Esketamine combining Sufentanil. Compared analgesic effects, time of birth course, adverse reactions, pain intensity, scores assigned to depression and anxiety before analgesia and after delivery were made for pregnant women in both groups. </div><div class="abstract-label">Results</div><div class="abstract-content">The response rates of the study and control groups reached 100% and 93%, respectively, with statistically significant differences (p=0.02). The time of the first, second, and third stages of labor in the study group were all significantly lower than that of the control group; showing statistical significance (p=0.00). Regarding adverse reactions showed no statistically significant differences (p=0.44). Moreover, the study group showed noticeably lower pain intensity than those of the control group during delivery, 20 minutes and one hour after delivery; and their differences were statistically significant (p=0.00). After delivery, both the SAS and SDS of the study group were respectively lower than those of the control group, with statistically significant differences as well (p=0.00). </div><div class="abstract-label">Conclusions</div><div class="abstract-content">Applying Esketamine combining Sufentanil in epidural painless delivery produces rather favorable analgesic effects, shortens the time of the birth process, and improves postpartum anxiety and depression without leading to more adverse reactions. </div> <a href="javascript:ShowArticleAbstract(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" id="articleKeywords25" class="article-abstract"> <b style="display: block; padding-bottom: 0.5rem; font-size: 1rem;">Key Words</b> <ul><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Clinical+effect%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Clinical effect</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Esketamine</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Labor+analgesia%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Labor analgesia</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Postpartum+depression%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Postpartum depression</a></li><li><a href="/search?page=1&sort=&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Sufentanil%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" target="_blank">Sufentanil</a></li></ul> <a href="javascript:ShowArticleKeywords(25);" target="_self" style="float: right;">Collapse</a> </div> <div style="display: none" 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href="/Search?page=11&sort=pdate&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" style="margin-left:0px;">11</a><a class="dxp-num page-number" href="/Search?page=12&sort=pdate&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" style="margin-left:0px;">12</a><a class="dxp-button dxp-bi" onclick="ASPx.PGNav(event);" href="/Search?page=2&sort=pdate&term=%5b%7b%22c%22%3anull%2c%22id%22%3a%22kw%22%2c%22o%22%3a%22eq%22%2c%22v%22%3a%22Esketamine%22%2c%22b%22%3anull%2c%22f%22%3anull%7d%5d" style="margin-left:0px;"><img class="dxWeb_pNext_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Next" /></a> </div><b class="dx-clear"></b><script id="dxss_1983253530" type="text/javascript">  </script> </div> </div> <div class="cl"></div> </div> </div> </div> <table class="dxlpLoadingPanel_MetropolisBlue dxlpControl_MetropolisBlue" id="RootHolder_LeftLoadingPanel" style="position:absolute;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="text-align:Center;vertical-align:Top;"><span id="RootHolder_LeftLoadingPanel_TL">Loading…</span></td> </tr> </table><div id="RootHolder_LeftLoadingPanel_LD" class="dxlpLoadingDiv_MetropolisBlue dxlpControl_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1950550554" type="text/javascript">  </script> <div id="RootHolder_articleCitationPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:450px;width:600px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content">    </div> </div> </div> </div><div id="RootHolder_articleCitationPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleCitationPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleCitationPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleCitationPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1115091042" type="text/javascript">  </script> <div id="RootHolder_chartPopupControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:1000px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_chartPopupControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam"></span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_chartPopupControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_chartPopupControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_chartPopupControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_chartPopupControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_420552910" type="text/javascript">  </script> <div id="RootHolder_pcImportArticlesControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:50px;width:50px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcImportArticlesControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Import Articles</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="RootHolder_pcImportArticlesControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcImportArticlesControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcImportArticlesControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcImportArticlesControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_365297802" type="text/javascript">  </script> <div id="RootHolder_pcEditArticleControl_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_pcEditArticleControl_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Edit My Journal Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content" style="overflow-x:hidden;overflow-y:scroll;">    </div> </div> </div> </div><div id="RootHolder_pcEditArticleControl_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_pcEditArticleControl_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_pcEditArticleControl_TL">Loading…</span></td> </tr> </table><div id="RootHolder_pcEditArticleControl_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_298765222" type="text/javascript">  </script> <div id="RootHolder_userIndexComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:400px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Article Influence Index</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle2">Article Influence Index</span></b> </p> <p> Total Citations in Crossref ÷ Total Articles = <span id="RootHolder_userIndexComputePopup_InfluenceIndexTitle3">Article Influence Index</span><sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="RootHolder_userIndexComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_userIndexComputePopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_userIndexComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1286575841" type="text/javascript">  </script> <div id="RootHolder_articleExportPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:280px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow" style="font-size:11pt;"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-maximizeBtn"> <img id="RootHolder_articleExportPopup_HMXB-1Img" class="dxWeb_pcMaximizeButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Maximize/Restore" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Export Articles to File</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="dxtcLite_MetropolisBlue dxtcSys dxtc-init dxtc-top dxtc-pc" id="RootHolder_articleExportPopup_ExportFilePageControl" style="width:100%;"> <ul class="dxtc-strip dxtc-row dxtc-stripContainer"> <li class="dxtc-leftIndent"> </li><li class="dxtc-tab dxtc-lead" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-activeTab dxtc-lead"><a class="dxtc-link"><span class="dx-vam">Export Article Detail</span></a></li><li class="dxtc-spacer"> </li><li class="dxtc-tab dxtc-last"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-activeTab dxtc-last" style="display:none;"><a class="dxtc-link"><span class="dx-vam">Export Citation Analysis</span></a></li><li class="dxtc-rightIndent"> </li> </ul><div class="dxtc-content"> <div> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_SearchTermText1">Esketamine (287 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:5px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_1662381219" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ExportDetailEndIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportDetailEndIndex')" value="287" type="text" /></td> </tr> </table><script id="dxss_616434442" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$selectDetailSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_selectDetailSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_1167331127" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_54524200" type="text/javascript">  </script><script id="dxss_1678130197" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" style="font-weight:bold;">JCR Year:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_VI" type="hidden" value="2023" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear')" value="2023" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$JCRYear$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_JCRYear_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2023</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2022</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">2021</td> </tr> </table> </div></td> </tr> </table><script id="dxss_830317689" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_167955898" type="text/javascript">  </script><script id="dxss_2013408041" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:5px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$DetailFileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1062639383" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_104403608" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_DetailFileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_1973673553" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_6" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLTSys dxflItemSys dxflCheckBoxWithTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" style="font-weight:bold;">Record Content:</label></td> </tr><tr> <td class="dxflNestedControlCell_MetropolisBlue"> <table> <tr> <td style="vertical-align: middle; padding: 5px;"> <table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields" style="color:#BD4100;"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_cbSelectAllFields_S" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$cbSelectAllFields" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label>Select All Fields</label></td> </tr> </table><script id="dxss_1176833720" type="text/javascript">  </script> </td> </tr> <tr> <td style="padding: 5px;"> <table class="dxeCheckBoxList_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields" style="width:100%;border-collapse:separate;"> <tr> <td class="dxe"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields" /><table style="width:100%;"> <tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB0_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB0" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Author(s)</label></td> </tr> </table><script id="dxss_771536870" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB1_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB1" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Title</label></td> </tr> </table><script id="dxss_1086331335" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB2_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB2" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Keywords</label></td> </tr> </table><script id="dxss_1308541020" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB3_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB3" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">MESH Headings</label></td> </tr> </table><script id="dxss_896786043" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB4_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB4" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Journal Title</label></td> </tr> </table><script id="dxss_450242410" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB5_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB5" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Year</label></td> </tr> </table><script id="dxss_765036875" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB6_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB6" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Article Type</label></td> </tr> </table><script id="dxss_1629835480" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB7_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB7" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Language</label></td> </tr> </table><script id="dxss_1218080503" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB8_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB8" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Published Date</label></td> </tr> </table><script id="dxss_1428514578" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB9_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB9" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author</label></td> </tr> </table><script id="dxss_1113720113" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB10_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB10" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">First Author’s Affiliations</label></td> </tr> </table><script id="dxss_310841941" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB11_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB11" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author</label></td> </tr> </table><script id="dxss_1301541094" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB12_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB12" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Corresponding Author’s Affiliations</label></td> </tr> </table><script id="dxss_675718561" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB13_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB13" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Email</label></td> </tr> </table><script id="dxss_2006865700" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB14_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB14" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">All Authors's Affiliations</label></td> </tr> </table><script id="dxss_1204905793" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB15_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB15" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Grant</label></td> </tr> </table><script id="dxss_407477242" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB16_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB16" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">ISSN</label></td> </tr> </table><script id="dxss_218345291" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB17_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB17" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Publisher</label></td> </tr> </table><script id="dxss_1394037744" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB18_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB18" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexing / Abstracting</label></td> </tr> </table><script id="dxss_319681069" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB19_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB19" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Factor</label></td> </tr> </table><script id="dxss_1292701966" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB20_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB20" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">JCR Quartile</label></td> </tr> </table><script id="dxss_1844280938" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB21_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB21" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Impact Index Per Article</label></td> </tr> </table><script id="dxss_838303323" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB22_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB22" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Category</label></td> </tr> </table><script id="dxss_1464125856" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB23_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB23" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Times Cited in RCA</label></td> </tr> </table><script id="dxss_148257179" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB24_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB24" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Peer-Reviewed Journal</label></td> </tr> </table><script id="dxss_950217086" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB25_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB25" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Open Access</label></td> </tr> </table><script id="dxss_1732367175" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB26_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB26" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">DOI</label></td> </tr> </table><script id="dxss_1936777588" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB27_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB27" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">PMID</label></td> </tr> </table><script id="dxss_745806673" type="text/javascript">  </script></td> </tr><tr> <td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB28_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB28" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Citation</label></td> </tr> </table><script id="dxss_1835441810" type="text/javascript">  </script></td><td><table class="dxeBase_MetropolisBlue dxeTAR" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29"> <tr> <td class="dxichCellSys"><span class="dxWeb_edtCheckBoxUnchecked_MetropolisBlue dxICheckBox_MetropolisBlue dxichSys dx-not-acc"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ArticleFieldExportFields_RB29_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportDetailPopupFormLayout$ArticleFieldExportFields$RB29" value="I" type="text" readonly="readonly" style="border-width:0;width:0;height:0;padding:0;margin:0;position:relative;background-color:transparent;display:block;" /></span></td><td class="dxichTextCellSys"><label class="dx-wrap">Indexed in RCA</label></td> </tr> </table><script id="dxss_847142451" type="text/javascript">  </script></td><td></td><td></td> </tr> </table></td> </tr> </table><script id="dxss_1169734383" type="text/javascript">  </script> </td> </tr> </table> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_7" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportDetailPopupFormLayout_ExportedDetailFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_1198171345" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_1960175520" type="text/javascript">  </script> </div> </div><div style="display:none;"> <div> <div class="dxflFormLayout_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout" style="font-size:11pt;width:100%;"> <table class="dxflGroup_MetropolisBlue dxflGroupSys dxflAGSys" style="border-collapse:separate;"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_0_Cap" class="dxDefaultCursor dxflCaption_MetropolisBlue" style="font-weight:bold;">Searched Name:</span></td><td class="dxflNestedControlCell_MetropolisBlue"> <span class="dxeBase_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_SearchTermText2">Esketamine (287 results from Reference Citation Analysis)</span> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_1" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="padding-bottom:10px;"> <table> <tr> <td> <span style="font-weight: bold">Article Number From</span> </td> <td>   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportStartIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportStartIndex')" value="1" type="text" /></td> </tr> </table><script id="dxss_814491935" type="text/javascript">  </script> </td> <td>  to   </td> <td> <table class="dxeTextBoxSys dxeTextBox_MetropolisBlue dxeTextBoxDefaultWidthSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex" style="width:80px;"> <tr> <td class="dxic" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$ExportEndSIndex" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" onchange="ASPx.EValueChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportEndSIndex')" value="287" type="text" /></td> </tr> </table><script id="dxss_1331245653" type="text/javascript">  </script> </td> <td>  </td> <td>(No more than 600 records at a time.) </td> </tr> </table> </div></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_2" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:10px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" style="font-weight:bold;">Indexing:</label></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource" style="width:200px;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_VI" type="hidden" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource')" value="Please Select" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100" class="dxeButton dxeButtonEditButton_MetropolisBlue dxeButtonEditClearButton_MetropolisBlue" onmousedown="ASPx.BEClear('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="display:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-100Img" class="dxEditors_edtClear_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="x" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$selectSource$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_selectSource_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr> <td></td> </tr> </table> </div></td> </tr> </table><script id="dxss_2046065225" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_1926633208" type="text/javascript">  </script><script id="dxss_228619664" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_4" class="dxflGroupCell_MetropolisBlue"><table class="dxflCLLSys dxflItemSys dxflTextEditItemSys dxflItem_MetropolisBlue" style="border-collapse:separate;padding-bottom:20px;"> <tr> <td class="dxflHALSys dxflVATSys dxflCaptionCell_MetropolisBlue dxflCaptionCellSys"><label class="dxflCaption_MetropolisBlue" for="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" style="font-weight:bold;">Format:</label><em class="dxflRequired_MetropolisBlue">*</em></td><td class="dxflNestedControlCell_MetropolisBlue"> <table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_ET" class="dxeValidDynEditorTable dxeRoot_MetropolisBlue"> <tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_CC"><table class="dxeButtonEditSys dxeButtonEdit_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat" style="width:200px;border-collapse:separate;"> <tr> <td style="display:none;"><input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" name="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_VI" type="hidden" value="1" /></td><td class="dxic" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="width:100%;"><input class="dxeEditArea_MetropolisBlue dxeEditAreaSys" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_I" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat" onfocus="ASPx.EGotFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onblur="ASPx.ELostFocus('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" onchange="ASPx.ETextChanged('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat')" value="Excel" type="text" /></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1" class="dxeButton dxeButtonEditButton_MetropolisBlue" onmousedown="return ASPx.DDDropDown('RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat', event)" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"><img id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_B-1Img" class="dxEditors_edtDropDown_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="v" /></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_PW-1" class="dxpcDropDown_MetropolisBlue dxpclW dxpc-ddSys" style="z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper"> <div class="dxpc-content"> <table class="dxeListBox_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L" style="border-collapse:separate;"> <tr> <td style="vertical-align:Top;"><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_D" class="dxlbd" style="width:100%;overflow-x:hidden;overflow-y:auto;"> <input id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_VI" type="hidden" name="ctl00$RootHolder$articleExportPopup$ExportFilePageControl$ExportPopupFormLayout$FileFormat$DDD$L" /><table style="border-collapse:separate;visibility:hidden!important;display:none!important;"> <tr id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBI-1" class="dxeListBoxItemRow_MetropolisBlue"> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBII" class="dxeListBoxItem_MetropolisBlue"> </td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_DDD_L_LBT" style="width:100%;border-collapse:separate;"> <tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Excel</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">Plain Text</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">PDF</td> </tr><tr class="dxeListBoxItemRow_MetropolisBlue"> <td class="dxeListBoxItem_MetropolisBlue">WORD</td> </tr> </table> </div></td> </tr> </table><script id="dxss_1509722775" type="text/javascript">  </script> </div> </div> </div> </div><script id="dxss_960798088" type="text/javascript">  </script></td><td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_EC" class="dxeErrorCell_MetropolisBlue dxeErrorFrame_MetropolisBlue dxeErrorFrameSys dxeErrorCellSys dxeNoBorderLeft" style="vertical-align:middle;display:none;white-space:nowrap;">Invalid value</td> </tr> </table><table id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LP" class="dxeLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_FileFormat_LD" class="dxeLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_835950349" type="text/javascript">  </script> </td> </tr> </table></td> </tr><tr> <td id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_5" class="dxflGroupCell_MetropolisBlue"><div class="dxflNestedControlCell_MetropolisBlue dxflCLLSys dxflItemSys dxflTextItemSys dxflItem_MetropolisBlue"> <a class="dxeHyperlink_MetropolisBlue" id="RootHolder_articleExportPopup_ExportFilePageControl_ExportPopupFormLayout_ExportedFileLink" target="_blank" rel="noopener noreferrer">Click to Download the Exported File</a><script id="dxss_308093146" type="text/javascript">  </script> </div></td> </tr> </table> </div><script id="dxss_424125632" type="text/javascript">  </script> </div> </div> </div> </div><b class="dx-clear"></b><table id="RootHolder_articleExportPopup_ExportFilePageControl_LP" class="dxtcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="RootHolder_articleExportPopup_ExportFilePageControl_TL">Loading…</span></td> </tr> </table><script id="dxss_2124675053" type="text/javascript">  </script> </div> </div><div class="dxpc-footer"> <div class="popup-footer-button-container"> <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnExportArticles_I" class="dxb-hb" value="Export" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnExportArticles" /><span class="dx-vam">Export</span> </div> </div><script id="dxss_77486387" type="text/javascript">  </script>    <div class="dxbButton_MetropolisBlue DefaultButton dxbButtonSys dxbTSys" id="RootHolder_articleExportPopup_TPCFm1_btnCancel" style="user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxb"> <input id="RootHolder_articleExportPopup_TPCFm1_btnCancel_I" class="dxb-hb" value="Cancel" type="submit" name="ctl00$RootHolder$articleExportPopup$TPCFm1$TC$btnCancel" /><span class="dx-vam">Cancel</span> </div> </div><script id="dxss_2118985763" type="text/javascript">  </script> </div> </div> </div> </div><div id="RootHolder_articleExportPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="RootHolder_articleExportPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="font-size:11pt;left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="font-size:11pt;padding-left:0px;"><span id="RootHolder_articleExportPopup_TL">Loading…</span></td> </tr> </table><div id="RootHolder_articleExportPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_578446409" type="text/javascript">  </script> </div> <div class="bottom-part cl"> © 2004-2024 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA </div> <div class="scroll"> <a href="#top" target="_self"> <img src="/Contents/Images/backtop3.png" /> </a> </div> <div id="categorySelectorPopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:800px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header drag dxpc-withBtn" style="font-size:20px;user-select:none;-khtml-user-select:none;-ms-user-select:none;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Select the Category</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="categorySelectorPopup_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="categorySelectorPopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="categorySelectorPopup_TL">Loading…</span></td> </tr> </table><div id="categorySelectorPopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_166253781" type="text/javascript">  </script> <div id="pcLoginPopUp_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:500px;width:700px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-contentWrapper" style="overflow:auto;"> <div class="dxpc-content"> </div> </div> </div> </div><div id="pcLoginPopUp_DXPWMB-1" class="dxpcModalBackLite_MetropolisBlue" style="z-index:9999;"> </div><table id="pcLoginPopUp_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="pcLoginPopUp_TL">Loading…</span></td> </tr> </table><div id="pcLoginPopUp_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_430910140" type="text/javascript">  </script> <div id="aiComputePopup_PW-1" class="dxpcLite_MetropolisBlue dxpclW" style="height:200px;width:300px;z-index:10000;display:none;visibility:hidden;"> <div class="dxpc-mainDiv dxpc-shadow"> <div class="dxpc-header dxpc-withBtn" style="font-size:20px;"> <div class="dxpc-closeBtn"> <img class="dxWeb_pcCloseButton_MetropolisBlue" src="/DXR.axd?r=1_58-HCSds" alt="Close" /> </div><div class="dxpc-headerContent"> <span class="dxpc-headerText dx-vam">Impact Index Per Article</span> </div><b class="dx-clear"></b> </div><div class="dxpc-contentWrapper"> <div class="dxpc-content"> <div class="ai-content-container"> <p> <b>Calculation for Impact Index Per Article</b> </p> <p> Times Cited ÷ Number of Years = Impact Index Per Article<sup class="standard-yellow">TM</sup> </p> </div> </div> </div> </div> </div><table id="aiComputePopup_LP" class="dxpcLoadingPanel_MetropolisBlue dxlpLoadingPanel_MetropolisBlue" style="left:0px;top:0px;z-index:30000;display:none;"> <tr> <td class="dx" style="padding-right:0px;"><img class="dxlp-loadingImage dxlp-imgPosLeft" src="/DXR.axd?r=1_58-HCSds" alt="" style="vertical-align:middle;" /></td><td class="dx" style="padding-left:0px;"><span id="aiComputePopup_TL">Loading…</span></td> </tr> </table><div id="aiComputePopup_LD" class="dxpcLoadingDiv_MetropolisBlue dxlpLoadingDiv_MetropolisBlue dx-ft" style="left:0px;top:0px;z-index:29999;display:none;position:absolute;"> </div><script id="dxss_698179129" type="text/javascript">  </script> <script type="text/javascript"> //<![CDATA[ var callBackFrameUrl='/WebResource.axd?d=beToSAE3vdsL1QUQUxjWdX-3aFLejnBliGvqSCZYULGFdxZmRlcJcqs71AKVNTQEXljNmd0slFkUZ_AFaCke4Q2&t=638628207619783110'; WebForm_InitCallback();//]]> </script> </form> </body> </html>