CINXE.COM

Autophagy Interactive Pathway: R&D Systems

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class="mobile_facet_wrapper"> <div class="search_mobile_buttons"> <div class="pw_toggle btn btn-tertiary"> Back to Pathways </div> </div> <div class="pw_menu_block"> <div class="et-pathways-topics pathway_menu_items"> <div class="pathways-block"> <h5 class="pathways-title"> <a href="/pathways">Interactive Pathways & Processes</a></h5> <ul class="pathways-ul" data-count="10" id="menuPathways"> <li class="pathways-li "> <form id="pathways_cancer_pathways" action="/pathways/cancer" method="post"> <a href="/pathways/cancer" data-form="pathways_cancer_pathways" class="pathway_link"> <span class="icon-"> Cancer Pathways </span> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </li> <li class="pathways-li "> <form id="pathways_cardiovascular_biology_pathways" action="/pathways/cardiovascular-biology" method="post"> <a href="/pathways/cardiovascular-biology" data-form="pathways_cardiovascular_biology_pathways" class="pathway_link"> <span class="icon-"> Cardiovascular Biology 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value="ubiquitin-related-modifiers-and-pathways"> </form> </li> </ul> </div> </div> </div> </div> </div> <div class="pw_right col-xs-12 col-sm-8 col-md-9"> <div class="search_mobile_buttons"> <div class="pw_menu_toggle btn btn-tertiary">Show Categories</div> </div> <div class="pw_header"> <h1>Autophagy Pathway</h1> <p id="pw-intro-txt">Click on one of the choices shown in the Explore Pathways box to highlight that portion of the pathway.<br></p> <div id="pw-con" data-mapname="" data-primary_segment="autophagy_all"> <div id="pw-main-nav-wrapper"> <div class="row"> <div id="pw-button-nav-top" class="col-xs-12 col-sm-12"> <div class="row"> <div id="pw-button-nav"> <div class="dropdown col-xs-12 col-sm-6 col-md-4"> <button class="btn-pw" type="button" data-toggle="dropup">Explore Pathways<span class="caret"></span></button> <ul id="pathwaynav" class="dropdown-content"> <li data-segment="Autophagy_Formation" data-background_image="Phagophore-formation.png" data-pathway_segment="Pathway_Autophagy_Formation" class="pw_rdblue_sm pw_sm_btn"><span>Phagophore Formation</span></li> <li data-segment="Autophagy_Elongation" data-background_image="Phagophore-elongation.png" data-pathway_segment="Pathway_Autophagy_Elongation" class="pw_rdblue_sm pw_sm_btn"><span>Phagophore Elongation</span></li> <li data-segment="Autophagy_Autophagosome" data-background_image="Autophagosome.png" data-pathway_segment="Pathway_Autophagy_Autophagosome" class="pw_rdblue_sm pw_sm_btn"><span>Autophagosome Formation</span></li> <li data-segment="Autophagy_Autolysosome" data-background_image="Autolysosomal.png" data-pathway_segment="Pathway_Autophagy_Autolysosome" class="pw_rdblue_sm pw_sm_btn"><span>Autolysosomal Degradation</span></li> <li data-segment="Autophagy_All" data-background_image="Autophaghy_all.png" data-pathway_segment="Pathway_Autophagy_All" class="pw_sm_btn-active"><span>View Full Pathway</span></li> </ul> </div> </div> <div class="col-xs-12 col-sm-6 col-md-5" > <div id="pw-nav-subtitle"> Autophagy Pathway </div> </div> <div id="pw-print-button-col" class="col-xs-12 col-sm-6 col-md-3" > <a href="#print-copy-form" id="btn-get-print-copy" class="btn btn-primary"><img class="btn-icon" src="https://resources.rndsystems.com/images/Pathways/icons/icon-image.svg"/> Get Print Copy</a> </div> </div> </div> </div> </div> <div id="pw-map"> <div id="pw-maps"> <div id="el1_gry" class="autophagy_all autophagy_formation pw-sprite el-gray1 pw-gray" style="top:108px;left:211px;"> </div> <div id="el1_off" data-id="1" data-set="EndophilinB1Bif-11" data-type="" class="autophagy_all autophagy_formation pw-sprite el-off1" style="top:108px;left:211px;"> </div> <div id="el1_ct" class="pw-tooltip" data-id="1"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/endophilin-b1-bif-1">Endophilin B1/Bif-1</a><br> </div> </div> <div id="el2_gry" class="autophagy_all autophagy_formation pw-label el-gray2 pw-gray" style="top:72px;left:195px;"> Endophilin B1/<br>Bif-1 </div> <div id="el2_off" data-id="2" data-set="EndophilinB1Bif-11" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off2" style="top:72px;left:195px;"> Endophilin B1/<br>Bif-1</div> <div id="el2_ct" class="pw-tooltip" data-id="2"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/endophilin-b1-bif-1">Endophilin B1/Bif-1</a><br> </div> </div> <div id="el3_gry" class="autophagy_all autophagy_formation pw-sprite el-gray3 pw-gray" style="top:132px;left:240px;"> </div> <div id="el3_off" data-id="3" data-set="mATG92" data-type="No Products Click" class="autophagy_all autophagy_formation pw-sprite el-off3" style="top:132px;left:240px;"> </div> <div id="el3_ct" class="pw-tooltip" data-id="3"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG9A">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el4_gry" class="autophagy_all autophagy_formation pw-label el-gray4 pw-gray" style="top:135px;left:260px;"> mATG9 </div> <div id="el4_off" data-id="4" data-set="mATG92" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off4" style="top:135px;left:260px;"> mATG9</div> <div id="el4_ct" class="pw-tooltip" data-id="4"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG9A">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el5_gry" class="autophagy_all autophagy_formation pw-label2 el-gray5 pw-gray" style="top:299px;left:46px;"> Omegasome </div> <div id="el5_off" data-id="5" data-set="Omegasome" data-type="" class="autophagy_all autophagy_formation pw-label2 el-off5" style="top:299px;left:46px;"> Omegasome</div> <div id="el5_ct" class="pw-tooltip" data-id="5"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el6_gry" class="autophagy_all autophagy_formation pw-label2 pw-center el-gray6 pw-gray" style="top:329px;left:188px;"> Released to<br>Endoplasmic<br>Reticulum </div> <div id="el6_off" data-id="6" data-set="ReleasedtoEndoplasmicReticulum" data-type="" class="autophagy_all autophagy_formation pw-label2 pw-center el-off6" style="top:329px;left:188px;"> Released to<br>Endoplasmic<br>Reticulum</div> <div id="el6_ct" class="pw-tooltip" data-id="6"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el7_gry" class="autophagy_all autophagy_formation pw-sprite el-gray7 pw-gray" style="top:167px;left:340px;"> </div> <div id="el7_off" data-id="7" data-set="ULK15" data-type="" class="autophagy_all autophagy_formation pw-sprite el-off7" style="top:167px;left:340px;"> </div> <div id="el7_ct" class="pw-tooltip" data-id="7"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el8_gry" class="autophagy_all autophagy_formation pw-label el-gray8 pw-gray" style="top:170px;left:360px;"> ULK1 </div> <div id="el8_off" data-id="8" data-set="ULK15" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off8" style="top:170px;left:360px;"> ULK1</div> <div id="el8_ct" class="pw-tooltip" data-id="8"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el9_gry" class="autophagy_all autophagy_formation pw-sprite el-gray9 pw-gray" style="top:162px;left:328px;"> </div> <div id="el9_off" data-id="9" data-set="ULK26" data-type="No Products Click" class="autophagy_all autophagy_formation pw-sprite el-off9" style="top:162px;left:328px;"> </div> <div id="el9_ct" class="pw-tooltip" data-id="9"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK2">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el10_gry" class="autophagy_all autophagy_formation pw-label2 el-gray10 pw-gray" style="top:155px;left:300px;"> ULK2 </div> <div id="el10_off" data-id="10" data-set="ULK26" data-type="" class="autophagy_all autophagy_formation pw-label2 el-off10" style="top:155px;left:300px;"> ULK2</div> <div id="el10_ct" class="pw-tooltip" data-id="10"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el11_gry" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-gray11 pw-gray" style="top:168px;left:316px;"> </div> <div id="el11_off" data-id="11" data-set="RB1CC17" data-type="" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-off11" style="top:168px;left:316px;"> </div> <div id="el11_ct" class="pw-tooltip" data-id="11"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el12_gry" class="autophagy_all autophagy_formation pw-label2 el-gray12 pw-gray" style="top:171px;left:268px;"> RB1CC1 </div> <div id="el12_off" data-id="12" data-set="RB1CC17" data-type="" class="autophagy_all autophagy_formation pw-label2 el-off12" style="top:171px;left:268px;"> RB1CC1</div> <div id="el12_ct" class="pw-tooltip" data-id="12"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el13_gry" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-gray13 pw-gray" style="top:174px;left:328px;"> </div> <div id="el13_off" data-id="13" data-set="ATG138" data-type="" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-off13" style="top:174px;left:328px;"> </div> <div id="el13_ct" class="pw-tooltip" data-id="13"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el14_gry" class="autophagy_all autophagy_formation pw-label el-gray14 pw-gray" style="top:189px;left:293px;"> ATG13 </div> <div id="el14_off" data-id="14" data-set="ATG138" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off14" style="top:189px;left:293px;"> ATG13</div> <div id="el14_ct" class="pw-tooltip" data-id="14"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG13">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el15_gry" class="autophagy_all autophagy_formation pw-sprite el-gray15 pw-gray" style="top:260px;left:307px;"> </div> <div id="el15_off" data-id="15" data-set="Beclin19" data-type="No Products Click" class="autophagy_all autophagy_formation pw-sprite el-off15" style="top:260px;left:307px;"> </div> <div id="el15_ct" class="pw-tooltip" data-id="15"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el16_gry" class="autophagy_all autophagy_formation pw-label el-gray16 pw-gray" style="top:253px;left:266px;"> Beclin 1 </div> <div id="el16_off" data-id="16" data-set="Beclin19" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off16" style="top:253px;left:266px;"> Beclin 1</div> <div id="el16_ct" class="pw-tooltip" data-id="16"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el17_gry" class="autophagy_all autophagy_formation pw-sprite el-gray17 pw-gray" style="top:267px;left:296px;"> </div> <div id="el17_off" data-id="17" data-set="hVps3410" data-type="No Products Click" class="autophagy_all autophagy_formation pw-sprite el-off17" style="top:267px;left:296px;"> </div> <div id="el17_ct" class="pw-tooltip" data-id="17"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el18_gry" class="autophagy_all autophagy_formation pw-label el-gray18 pw-gray" style="top:265px;left:255px;"> hVps34 </div> <div id="el18_off" data-id="18" data-set="hVps3410" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off18" style="top:265px;left:255px;"> hVps34</div> <div id="el18_ct" class="pw-tooltip" data-id="18"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el19_gry" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-gray19 pw-gray" style="top:277px;left:287px;"> </div> <div id="el19_off" data-id="19" data-set="PIK3R411" data-type="No Products Click" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-off19" style="top:277px;left:287px;"> </div> <div id="el19_ct" class="pw-tooltip" data-id="19"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el20_gry" class="autophagy_all autophagy_formation pw-label el-gray20 pw-gray" style="top:281px;left:245px;"> PIK3R4 </div> <div id="el20_off" data-id="20" data-set="PIK3R411" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off20" style="top:281px;left:245px;"> PIK3R4</div> <div id="el20_ct" class="pw-tooltip" data-id="20"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pik3r4">PIK3R4</a><br> </div> </div> <div id="el21_gry" class="autophagy_all autophagy_formation pw-sprite el-gray21 pw-gray" style="top:272px;left:314px;"> </div> <div id="el21_off" data-id="21" data-set="Ambra112" data-type="No Products Click" class="autophagy_all autophagy_formation pw-sprite el-off21" style="top:272px;left:314px;"> </div> <div id="el21_ct" class="pw-tooltip" data-id="21"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Ambra1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el22_gry" class="autophagy_all autophagy_formation pw-label el-gray22 pw-gray" style="top:297px;left:276px;"> Ambra1 </div> <div id="el22_off" data-id="22" data-set="Ambra112" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off22" style="top:297px;left:276px;"> Ambra1</div> <div id="el22_ct" class="pw-tooltip" data-id="22"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=Ambra1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el23_gry" class="autophagy_all autophagy_formation pw-label el-gray23 pw-gray" style="top:288px;left:347px;"> Microtubule </div> <div id="el23_off" data-id="23" data-set="Microtubule13" data-type="No Products Click" class="autophagy_all autophagy_formation pw-label el-off23" style="top:288px;left:347px;"> Microtubule</div> <div id="el23_ct" class="pw-tooltip" data-id="23"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beta-iii-tubulin">beta-III Tubulin</a><br> </div> </div> <div id="el24_gry" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-gray24 pw-gray" style="top:268px;left:327px;"> </div> <div id="el24_off" data-id="24" data-set="Dynein14" data-type="No Products Click" class="autophagy_all autophagy_formation pw-sprite pw-sprite-inactive el-off24" style="top:268px;left:327px;"> </div> <div id="el24_ct" class="pw-tooltip" data-id="24"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el25_gry" class="autophagy_all autophagy_formation pw-label2 el-gray25 pw-gray" style="top:243px;left:344px;"> Dynein </div> <div id="el25_off" data-id="25" data-set="Dynein14" data-type="" class="autophagy_all autophagy_formation pw-label2 el-off25" style="top:243px;left:344px;"> Dynein</div> <div id="el25_ct" class="pw-tooltip" data-id="25"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el26_gry" class="autophagy_all autophagy_formation pw-label2 pw-center el-gray26 pw-gray" style="top:35px;left:390px;"> Phagophore<br>Formation </div> <div id="el26_off" data-id="26" data-set="PhagophoreFormation" data-type="" class="autophagy_all autophagy_formation pw-label2 pw-center el-off26" style="top:35px;left:390px;"> Phagophore<br>Formation</div> <div id="el26_ct" class="pw-tooltip" data-id="26"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el27_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray27 pw-gray" style="top:112px;left:466px;"> </div> <div id="el27_off" data-id="27" data-set="ULK116" data-type="" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off27" style="top:112px;left:466px;"> </div> <div id="el27_ct" class="pw-tooltip" data-id="27"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el28_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray28 pw-gray" style="top:93px;left:431px;"> ULK1 </div> <div id="el28_off" data-id="28" data-set="ULK116" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off28" style="top:93px;left:431px;"> ULK1</div> <div id="el28_ct" class="pw-tooltip" data-id="28"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el29_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray29 pw-gray" style="top:122px;left:475px;"> </div> <div id="el29_off" data-id="29" data-set="ATG1317" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off29" style="top:122px;left:475px;"> </div> <div id="el29_ct" class="pw-tooltip" data-id="29"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG13">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el30_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray30 pw-gray" style="top:113px;left:417px;"> ATG13 </div> <div id="el30_off" data-id="30" data-set="ATG1317" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off30" style="top:113px;left:417px;"> ATG13</div> <div id="el30_ct" class="pw-tooltip" data-id="30"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG13">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el31_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray31 pw-gray" style="top:126px;left:462px;"> </div> <div id="el31_off" data-id="31" data-set="ULK218" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off31" style="top:126px;left:462px;"> </div> <div id="el31_ct" class="pw-tooltip" data-id="31"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK2">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el32_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray32 pw-gray" style="top:128px;left:419px;"> ULK2 </div> <div id="el32_off" data-id="32" data-set="ULK218" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off32" style="top:128px;left:419px;"> ULK2</div> <div id="el32_ct" class="pw-tooltip" data-id="32"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK2">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el33_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray33 pw-gray" style="top:135px;left:473px;"> </div> <div id="el33_off" data-id="33" data-set="RB1CC119" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off33" style="top:135px;left:473px;"> </div> <div id="el33_ct" class="pw-tooltip" data-id="33"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=RB1CC1%2FFIP200">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el34_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray34 pw-gray" style="top:141px;left:395px;"> RB1CC1 </div> <div id="el34_off" data-id="34" data-set="RB1CC119" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off34" style="top:141px;left:395px;"> RB1CC1</div> <div id="el34_ct" class="pw-tooltip" data-id="34"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=RB1CC1%2FFIP200">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el35_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray35 pw-gray" style="top:157px;left:452px;"> </div> <div id="el35_off" data-id="35" data-set="ATG1220" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off35" style="top:157px;left:452px;"> </div> <div id="el35_ct" class="pw-tooltip" data-id="35"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el36_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray36 pw-gray" style="top:160px;left:412px;"> ATG12 </div> <div id="el36_off" data-id="36" data-set="ATG1220" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off36" style="top:160px;left:412px;"> ATG12</div> <div id="el36_ct" class="pw-tooltip" data-id="36"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el37_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray37 pw-gray" style="top:153px;left:466px;"> </div> <div id="el37_off" data-id="37" data-set="ATG521" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off37" style="top:153px;left:466px;"> </div> <div id="el37_ct" class="pw-tooltip" data-id="37"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el38_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray38 pw-gray" style="top:176px;left:424px;"> ATG5 </div> <div id="el38_off" data-id="38" data-set="ATG521" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off38" style="top:176px;left:424px;"> ATG5</div> <div id="el38_ct" class="pw-tooltip" data-id="38"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el39_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray39 pw-gray" style="top:147px;left:478px;"> </div> <div id="el39_off" data-id="39" data-set="ATG16L22" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off39" style="top:147px;left:478px;"> </div> <div id="el39_ct" class="pw-tooltip" data-id="39"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el40_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray40 pw-gray" style="top:189px;left:426px;"> ATG16L </div> <div id="el40_off" data-id="40" data-set="ATG16L22" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off40" style="top:189px;left:426px;"> ATG16L</div> <div id="el40_ct" class="pw-tooltip" data-id="40"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el41_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray41 pw-gray" style="top:97px;left:508px;"> </div> <div id="el41_off" data-id="41" data-set="LC3-II23" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off41" style="top:97px;left:508px;"> </div> <div id="el41_ct" class="pw-tooltip" data-id="41"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el42_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray42 pw-gray" style="top:79px;left:501px;"> LC3-II </div> <div id="el42_off" data-id="42" data-set="LC3-II23" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off42" style="top:79px;left:501px;"> LC3-II</div> <div id="el42_ct" class="pw-tooltip" data-id="42"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el43_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray43 pw-gray" style="top:75px;left:552px;"> </div> <div id="el43_off" data-id="43" data-set="DFCP124" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off43" style="top:75px;left:552px;"> </div> <div id="el43_ct" class="pw-tooltip" data-id="43"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DFCP1%2FZFYVE1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el44_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray44 pw-gray" style="top:58px;left:542px;"> DFCP1 </div> <div id="el44_off" data-id="44" data-set="DFCP124" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off44" style="top:58px;left:542px;"> DFCP1</div> <div id="el44_ct" class="pw-tooltip" data-id="44"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DFCP1%2FZFYVE1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el45_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray45 pw-gray" style="top:56px;left:610px;"> </div> <div id="el45_off" data-id="45" data-set="Beclin125" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off45" style="top:56px;left:610px;"> </div> <div id="el45_ct" class="pw-tooltip" data-id="45"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el46_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray46 pw-gray" style="top:41px;left:651px;"> Beclin 1 </div> <div id="el46_off" data-id="46" data-set="Beclin125" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off46" style="top:41px;left:651px;"> Beclin 1</div> <div id="el46_ct" class="pw-tooltip" data-id="46"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el47_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray47 pw-gray" style="top:58px;left:626px;"> </div> <div id="el47_off" data-id="47" data-set="ATG14L26" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off47" style="top:58px;left:626px;"> </div> <div id="el47_ct" class="pw-tooltip" data-id="47"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG14L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el48_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray48 pw-gray" style="top:58px;left:656px;"> ATG14L </div> <div id="el48_off" data-id="48" data-set="ATG14L26" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off48" style="top:58px;left:656px;"> ATG14L</div> <div id="el48_ct" class="pw-tooltip" data-id="48"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG14L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el49_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray49 pw-gray" style="top:69px;left:616px;"> </div> <div id="el49_off" data-id="49" data-set="hVps3427" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off49" style="top:69px;left:616px;"> </div> <div id="el49_ct" class="pw-tooltip" data-id="49"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el50_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray50 pw-gray" style="top:72px;left:650px;"> hVps34 </div> <div id="el50_off" data-id="50" data-set="hVps3427" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off50" style="top:72px;left:650px;"> hVps34</div> <div id="el50_ct" class="pw-tooltip" data-id="50"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el51_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray51 pw-gray" style="top:82px;left:608px;"> </div> <div id="el51_off" data-id="51" data-set="PIK3R428" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off51" style="top:82px;left:608px;"> </div> <div id="el51_ct" class="pw-tooltip" data-id="51"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pik3r4">PIK3R4</a><br> </div> </div> <div id="el52_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray52 pw-gray" style="top:87px;left:643px;"> PIK3R4 </div> <div id="el52_off" data-id="52" data-set="PIK3R428" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off52" style="top:87px;left:643px;"> PIK3R4</div> <div id="el52_ct" class="pw-tooltip" data-id="52"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pik3r4">PIK3R4</a><br> </div> </div> <div id="el53_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray53 pw-gray" style="top:127px;left:618px;"> </div> <div id="el53_off" data-id="53" data-set="ATG1229" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off53" style="top:127px;left:618px;"> </div> <div id="el53_ct" class="pw-tooltip" data-id="53"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el54_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray54 pw-gray" style="top:133px;left:651px;"> ATG12 </div> <div id="el54_off" data-id="54" data-set="ATG1229" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off54" style="top:133px;left:651px;"> ATG12</div> <div id="el54_ct" class="pw-tooltip" data-id="54"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el55_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray55 pw-gray" style="top:117px;left:611px;"> </div> <div id="el55_off" data-id="55" data-set="ATG530" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off55" style="top:117px;left:611px;"> </div> <div id="el55_ct" class="pw-tooltip" data-id="55"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el56_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray56 pw-gray" style="top:120px;left:645px;"> ATG5 </div> <div id="el56_off" data-id="56" data-set="ATG530" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off56" style="top:120px;left:645px;"> ATG5</div> <div id="el56_ct" class="pw-tooltip" data-id="56"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el57_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray57 pw-gray" style="top:106px;left:605px;"> </div> <div id="el57_off" data-id="57" data-set="ATG16L31" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off57" style="top:106px;left:605px;"> </div> <div id="el57_ct" class="pw-tooltip" data-id="57"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el58_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray58 pw-gray" style="top:107px;left:639px;"> ATG16L </div> <div id="el58_off" data-id="58" data-set="ATG16L31" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off58" style="top:107px;left:639px;"> ATG16L</div> <div id="el58_ct" class="pw-tooltip" data-id="58"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el59_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray59 pw-gray" style="top:120px;left:544px;"> </div> <div id="el59_off" data-id="59" data-set="LC3-II32" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off59" style="top:120px;left:544px;"> </div> <div id="el59_ct" class="pw-tooltip" data-id="59"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el60_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray60 pw-gray" style="top:137px;left:541px;"> LC3-II </div> <div id="el60_off" data-id="60" data-set="LC3-II32" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off60" style="top:137px;left:541px;"> LC3-II</div> <div id="el60_ct" class="pw-tooltip" data-id="60"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el61_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray61 pw-gray" style="top:144px;left:517px;"> </div> <div id="el61_off" data-id="61" data-set="WIPI1233" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off61" style="top:144px;left:517px;"> </div> <div id="el61_ct" class="pw-tooltip" data-id="61"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=WIPI1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el62_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray62 pw-gray" style="top:162px;left:523px;"> WIPI1/2 </div> <div id="el62_off" data-id="62" data-set="WIPI1233" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off62" style="top:162px;left:523px;"> WIPI1/2</div> <div id="el62_ct" class="pw-tooltip" data-id="62"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=WIPI1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el63_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray63 pw-gray" style="top:193px;left:498px;"> </div> <div id="el63_off" data-id="63" data-set="Beclin134" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off63" style="top:193px;left:498px;"> </div> <div id="el63_ct" class="pw-tooltip" data-id="63"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el64_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray64 pw-gray" style="top:219px;left:526px;"> Beclin 1 </div> <div id="el64_off" data-id="64" data-set="Beclin134" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off64" style="top:219px;left:526px;"> Beclin 1</div> <div id="el64_ct" class="pw-tooltip" data-id="64"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el65_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray65 pw-gray" style="top:195px;left:510px;"> </div> <div id="el65_off" data-id="65" data-set="ATG14L35" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off65" style="top:195px;left:510px;"> </div> <div id="el65_ct" class="pw-tooltip" data-id="65"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG14L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el66_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray66 pw-gray" style="top:204px;left:532px;"> ATG14L </div> <div id="el66_off" data-id="66" data-set="ATG14L35" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off66" style="top:204px;left:532px;"> ATG14L</div> <div id="el66_ct" class="pw-tooltip" data-id="66"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG14L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el67_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray67 pw-gray" style="top:184px;left:504px;"> </div> <div id="el67_off" data-id="67" data-set="hVps3436" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off67" style="top:184px;left:504px;"> </div> <div id="el67_ct" class="pw-tooltip" data-id="67"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el68_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray68 pw-gray" style="top:188px;left:537px;"> hVps34 </div> <div id="el68_off" data-id="68" data-set="hVps3436" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off68" style="top:188px;left:537px;"> hVps34</div> <div id="el68_ct" class="pw-tooltip" data-id="68"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el69_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray69 pw-gray" style="top:182px;left:491px;"> </div> <div id="el69_off" data-id="69" data-set="VMP137" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off69" style="top:182px;left:491px;"> </div> <div id="el69_ct" class="pw-tooltip" data-id="69"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=VMP1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el70_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray70 pw-gray" style="top:231px;left:487px;"> VMP1 </div> <div id="el70_off" data-id="70" data-set="VMP137" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off70" style="top:231px;left:487px;"> VMP1</div> <div id="el70_ct" class="pw-tooltip" data-id="70"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=VMP1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el71_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray71 pw-gray" style="top:158px;left:587px;"> </div> <div id="el71_off" data-id="71" data-set="LC3-I38" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off71" style="top:158px;left:587px;"> </div> <div id="el71_ct" class="pw-tooltip" data-id="71"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el72_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray72 pw-gray" style="top:161px;left:608px;"> LC3-I </div> <div id="el72_off" data-id="72" data-set="LC3-I38" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off72" style="top:161px;left:608px;"> LC3-I</div> <div id="el72_ct" class="pw-tooltip" data-id="72"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el73_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray73 pw-gray" style="top:170px;left:582px;"> </div> <div id="el73_off" data-id="73" data-set="ATG339" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off73" style="top:170px;left:582px;"> </div> <div id="el73_ct" class="pw-tooltip" data-id="73"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg3">ATG3</a><br> </div> </div> <div id="el74_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray74 pw-gray" style="top:178px;left:602px;"> ATG3 </div> <div id="el74_off" data-id="74" data-set="ATG339" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off74" style="top:178px;left:602px;"> ATG3</div> <div id="el74_ct" class="pw-tooltip" data-id="74"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg3">ATG3</a><br> </div> </div> <div id="el75_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray75 pw-gray" style="top:178px;left:651px;"> </div> <div id="el75_off" data-id="75" data-set="ATG1040" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off75" style="top:178px;left:651px;"> </div> <div id="el75_ct" class="pw-tooltip" data-id="75"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg10">ATG10</a><br> </div> </div> <div id="el76_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray76 pw-gray" style="top:180px;left:672px;"> ATG10 </div> <div id="el76_off" data-id="76" data-set="ATG1040" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off76" style="top:180px;left:672px;"> ATG10</div> <div id="el76_ct" class="pw-tooltip" data-id="76"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg10">ATG10</a><br> </div> </div> <div id="el77_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray77 pw-gray" style="top:192px;left:647px;"> </div> <div id="el77_off" data-id="77" data-set="ATG1241" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off77" style="top:192px;left:647px;"> </div> <div id="el77_ct" class="pw-tooltip" data-id="77"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el78_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray78 pw-gray" style="top:196px;left:667px;"> ATG12 </div> <div id="el78_off" data-id="78" data-set="ATG1241" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off78" style="top:196px;left:667px;"> ATG12</div> <div id="el78_ct" class="pw-tooltip" data-id="78"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el79_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray79 pw-gray" style="top:230px;left:580px;"> </div> <div id="el79_off" data-id="79" data-set="ATG742" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off79" style="top:230px;left:580px;"> </div> <div id="el79_ct" class="pw-tooltip" data-id="79"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg7">ATG7</a><br> </div> </div> <div id="el80_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray80 pw-gray" style="top:233px;left:601px;"> ATG7 </div> <div id="el80_off" data-id="80" data-set="ATG742" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off80" style="top:233px;left:601px;"> ATG7</div> <div id="el80_ct" class="pw-tooltip" data-id="80"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg7">ATG7</a><br> </div> </div> <div id="el81_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray81 pw-gray" style="top:244px;left:576px;"> </div> <div id="el81_off" data-id="81" data-set="LC3-I43" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off81" style="top:244px;left:576px;"> </div> <div id="el81_ct" class="pw-tooltip" data-id="81"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el82_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray82 pw-gray" style="top:249px;left:597px;"> LC3-I </div> <div id="el82_off" data-id="82" data-set="LC3-I43" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off82" style="top:249px;left:597px;"> LC3-I</div> <div id="el82_ct" class="pw-tooltip" data-id="82"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el83_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray83 pw-gray" style="top:240px;left:663px;"> </div> <div id="el83_off" data-id="83" data-set="ATG744" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off83" style="top:240px;left:663px;"> </div> <div id="el83_ct" class="pw-tooltip" data-id="83"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg7">ATG7</a><br> </div> </div> <div id="el84_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray84 pw-gray" style="top:243px;left:684px;"> ATG7 </div> <div id="el84_off" data-id="84" data-set="ATG744" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off84" style="top:243px;left:684px;"> ATG7</div> <div id="el84_ct" class="pw-tooltip" data-id="84"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg7">ATG7</a><br> </div> </div> <div id="el85_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray85 pw-gray" style="top:253px;left:657px;"> </div> <div id="el85_off" data-id="85" data-set="ATG1245" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off85" style="top:253px;left:657px;"> </div> <div id="el85_ct" class="pw-tooltip" data-id="85"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el86_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray86 pw-gray" style="top:259px;left:677px;"> ATG12 </div> <div id="el86_off" data-id="86" data-set="ATG1245" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off86" style="top:259px;left:677px;"> ATG12</div> <div id="el86_ct" class="pw-tooltip" data-id="86"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el87_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray87 pw-gray" style="top:295px;left:612px;"> </div> <div id="el87_off" data-id="87" data-set="ATG4B46" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off87" style="top:295px;left:612px;"> </div> <div id="el87_ct" class="pw-tooltip" data-id="87"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg4b">ATG4B</a><br> </div> </div> <div id="el88_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray88 pw-gray" style="top:298px;left:634px;"> ATG4B </div> <div id="el88_off" data-id="88" data-set="ATG4B46" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off88" style="top:298px;left:634px;"> ATG4B</div> <div id="el88_ct" class="pw-tooltip" data-id="88"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg4b">ATG4B</a><br> </div> </div> <div id="el89_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-gray89 pw-gray" style="top:285px;left:574px;"> </div> <div id="el89_off" data-id="89" data-set="LC347" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-sprite el-off89" style="top:285px;left:574px;"> </div> <div id="el89_ct" class="pw-tooltip" data-id="89"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el90_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-gray90 pw-gray" style="top:288px;left:554px;"> LC3 </div> <div id="el90_off" data-id="90" data-set="LC347" data-type="No Products Click" class="autophagy_all autophagy_formation autophagy_elongation pw-label el-off90" style="top:288px;left:554px;"> LC3</div> <div id="el90_ct" class="pw-tooltip" data-id="90"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el91_gry" class="autophagy_all autophagy_formation autophagy_elongation pw-label2 el-gray91 pw-gray" style="top:301px;left:537px;"> (proteolytic<br>cleavage) </div> <div id="el91_off" data-id="91" data-set="proteolyticcleavage" data-type="" class="autophagy_all autophagy_formation autophagy_elongation pw-label2 el-off91" style="top:301px;left:537px;"> (proteolytic<br>cleavage)</div> <div id="el91_ct" class="pw-tooltip" data-id="91"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el92_gry" class="autophagy_all autophagy_elongation pw-label2 el-gray92 pw-gray" style="top:336px;left:479px;"> Elongation </div> <div id="el92_off" data-id="92" data-set="Elongation" data-type="" class="autophagy_all autophagy_elongation pw-label2 el-off92" style="top:336px;left:479px;"> Elongation</div> <div id="el92_ct" class="pw-tooltip" data-id="92"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el93_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray93 pw-gray" style="top:349px;left:621px;"> </div> <div id="el93_off" data-id="93" data-set="ATG4A50" data-type="" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off93" style="top:349px;left:621px;"> </div> <div id="el93_ct" class="pw-tooltip" data-id="93"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg4a">ATG4A</a><br> </div> </div> <div id="el94_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray94 pw-gray" style="top:353px;left:582px;"> ATG4A </div> <div id="el94_off" data-id="94" data-set="ATG4A50" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off94" style="top:353px;left:582px;"> ATG4A</div> <div id="el94_ct" class="pw-tooltip" data-id="94"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg4a">ATG4A</a><br> </div> </div> <div id="el95_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray95 pw-gray" style="top:349px;left:660px;"> </div> <div id="el95_off" data-id="95" data-set="GATE-1651" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off95" style="top:349px;left:660px;"> </div> <div id="el95_ct" class="pw-tooltip" data-id="95"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el96_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray96 pw-gray" style="top:334px;left:684px;"> GATE-16 </div> <div id="el96_off" data-id="96" data-set="GATE-1651" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off96" style="top:334px;left:684px;"> GATE-16</div> <div id="el96_ct" class="pw-tooltip" data-id="96"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el97_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label2 el-gray97 pw-gray" style="top:348px;left:682px;"> (proteolytic cleavage) </div> <div id="el97_off" data-id="97" data-set="proteolyticcleavage" data-type="" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label2 el-off97" style="top:348px;left:682px;"> (proteolytic cleavage)</div> <div id="el97_ct" class="pw-tooltip" data-id="97"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el98_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray98 pw-gray" style="top:407px;left:684px;"> </div> <div id="el98_off" data-id="98" data-set="GATE-16-I53" data-type="" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off98" style="top:407px;left:684px;"> </div> <div id="el98_ct" class="pw-tooltip" data-id="98"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el99_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray99 pw-gray" style="top:410px;left:625px;"> GATE-16-I </div> <div id="el99_off" data-id="99" data-set="GATE-16-I53" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off99" style="top:410px;left:625px;"> GATE-16-I</div> <div id="el99_ct" class="pw-tooltip" data-id="99"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el100_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray100 pw-gray" style="top:414px;left:693px;"> </div> <div id="el100_off" data-id="100" data-set="ATG754" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off100" style="top:414px;left:693px;"> </div> <div id="el100_ct" class="pw-tooltip" data-id="100"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg7">ATG7</a><br> </div> </div> <div id="el101_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray101 pw-gray" style="top:418px;left:712px;"> ATG7 </div> <div id="el101_off" data-id="101" data-set="ATG754" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off101" style="top:418px;left:712px;"> ATG7</div> <div id="el101_ct" class="pw-tooltip" data-id="101"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg7">ATG7</a><br> </div> </div> <div id="el102_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray102 pw-gray" style="top:482px;left:666px;"> </div> <div id="el102_off" data-id="102" data-set="ATG355" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off102" style="top:482px;left:666px;"> </div> <div id="el102_ct" class="pw-tooltip" data-id="102"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg3">ATG3</a><br> </div> </div> <div id="el103_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray103 pw-gray" style="top:487px;left:687px;"> ATG3 </div> <div id="el103_off" data-id="103" data-set="ATG355" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off103" style="top:487px;left:687px;"> ATG3</div> <div id="el103_ct" class="pw-tooltip" data-id="103"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg3">ATG3</a><br> </div> </div> <div id="el104_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray104 pw-gray" style="top:470px;left:658px;"> </div> <div id="el104_off" data-id="104" data-set="GATE-16-I56" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off104" style="top:470px;left:658px;"> </div> <div id="el104_ct" class="pw-tooltip" data-id="104"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el105_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray105 pw-gray" style="top:457px;left:620px;"> GATE-16-I </div> <div id="el105_off" data-id="105" data-set="GATE-16-I56" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off105" style="top:457px;left:620px;"> GATE-16-I</div> <div id="el105_ct" class="pw-tooltip" data-id="105"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el106_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray106 pw-gray" style="top:493px;left:607px;"> </div> <div id="el106_off" data-id="106" data-set="GATE-16-II57" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off106" style="top:493px;left:607px;"> </div> <div id="el106_ct" class="pw-tooltip" data-id="106"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el107_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray107 pw-gray" style="top:510px;left:616px;"> GATE-16-II </div> <div id="el107_off" data-id="107" data-set="GATE-16-II57" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off107" style="top:510px;left:616px;"> GATE-16-II</div> <div id="el107_ct" class="pw-tooltip" data-id="107"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el108_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label2 el-gray108 pw-gray" style="top:551px;left:596px;"> Phagophore </div> <div id="el108_off" data-id="108" data-set="Phagophore" data-type="" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label2 el-off108" style="top:551px;left:596px;"> Phagophore</div> <div id="el108_ct" class="pw-tooltip" data-id="108"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el109_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray109 pw-gray" style="top:424px;left:533px;"> </div> <div id="el109_off" data-id="109" data-set="ATG14L59" data-type="" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off109" style="top:424px;left:533px;"> </div> <div id="el109_ct" class="pw-tooltip" data-id="109"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG14L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el110_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray110 pw-gray" style="top:424px;left:553px;"> ATG14L </div> <div id="el110_off" data-id="110" data-set="ATG14L59" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off110" style="top:424px;left:553px;"> ATG14L</div> <div id="el110_ct" class="pw-tooltip" data-id="110"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG14L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el111_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray111 pw-gray" style="top:436px;left:541px;"> </div> <div id="el111_off" data-id="111" data-set="Beclin160" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off111" style="top:436px;left:541px;"> </div> <div id="el111_ct" class="pw-tooltip" data-id="111"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el112_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray112 pw-gray" style="top:436px;left:562px;"> Beclin 1 </div> <div id="el112_off" data-id="112" data-set="Beclin160" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off112" style="top:436px;left:562px;"> Beclin 1</div> <div id="el112_ct" class="pw-tooltip" data-id="112"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/beclin-1-atg6">Beclin 1/ATG6</a><br> </div> </div> <div id="el113_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray113 pw-gray" style="top:448px;left:537px;"> </div> <div id="el113_off" data-id="113" data-set="hVps3461" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off113" style="top:448px;left:537px;"> </div> <div id="el113_ct" class="pw-tooltip" data-id="113"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el114_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray114 pw-gray" style="top:450px;left:559px;"> hVps34 </div> <div id="el114_off" data-id="114" data-set="hVps3461" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off114" style="top:450px;left:559px;"> hVps34</div> <div id="el114_ct" class="pw-tooltip" data-id="114"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pi-3-kinase-c3">PI 3-Kinase C3</a><br> </div> </div> <div id="el115_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray115 pw-gray" style="top:462px;left:532px;"> </div> <div id="el115_off" data-id="115" data-set="PIK3R462" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off115" style="top:462px;left:532px;"> </div> <div id="el115_ct" class="pw-tooltip" data-id="115"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pik3r4">PIK3R4</a><br> </div> </div> <div id="el116_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray116 pw-gray" style="top:465px;left:552px;"> PIK3R4 </div> <div id="el116_off" data-id="116" data-set="PIK3R462" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off116" style="top:465px;left:552px;"> PIK3R4</div> <div id="el116_ct" class="pw-tooltip" data-id="116"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/pik3r4">PIK3R4</a><br> </div> </div> <div id="el117_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray117 pw-gray" style="top:462px;left:495px;"> </div> <div id="el117_off" data-id="117" data-set="DFCP163" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off117" style="top:462px;left:495px;"> </div> <div id="el117_ct" class="pw-tooltip" data-id="117"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DFCP1%2FZFYVE1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el118_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray118 pw-gray" style="top:464px;left:457px;"> DFCP1 </div> <div id="el118_off" data-id="118" data-set="DFCP163" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off118" style="top:464px;left:457px;"> DFCP1</div> <div id="el118_ct" class="pw-tooltip" data-id="118"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DFCP1%2FZFYVE1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el119_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray119 pw-gray" style="top:484px;left:464px;"> </div> <div id="el119_off" data-id="119" data-set="LC3-II64" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off119" style="top:484px;left:464px;"> </div> <div id="el119_ct" class="pw-tooltip" data-id="119"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el120_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray120 pw-gray" style="top:487px;left:432px;"> LC3-II </div> <div id="el120_off" data-id="120" data-set="LC3-II64" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off120" style="top:487px;left:432px;"> LC3-II</div> <div id="el120_ct" class="pw-tooltip" data-id="120"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el121_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray121 pw-gray" style="top:535px;left:432px;"> </div> <div id="el121_off" data-id="121" data-set="ATG1265" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off121" style="top:535px;left:432px;"> </div> <div id="el121_ct" class="pw-tooltip" data-id="121"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el122_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray122 pw-gray" style="top:538px;left:394px;"> ATG12 </div> <div id="el122_off" data-id="122" data-set="ATG1265" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off122" style="top:538px;left:394px;"> ATG12</div> <div id="el122_ct" class="pw-tooltip" data-id="122"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el123_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray123 pw-gray" style="top:524px;left:440px;"> </div> <div id="el123_off" data-id="123" data-set="ATG566" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off123" style="top:524px;left:440px;"> </div> <div id="el123_ct" class="pw-tooltip" data-id="123"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el124_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray124 pw-gray" style="top:524px;left:408px;"> ATG5 </div> <div id="el124_off" data-id="124" data-set="ATG566" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off124" style="top:524px;left:408px;"> ATG5</div> <div id="el124_ct" class="pw-tooltip" data-id="124"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el125_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray125 pw-gray" style="top:515px;left:448px;"> </div> <div id="el125_off" data-id="125" data-set="ATG16L67" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off125" style="top:515px;left:448px;"> </div> <div id="el125_ct" class="pw-tooltip" data-id="125"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el126_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray126 pw-gray" style="top:510px;left:403px;"> ATG16L </div> <div id="el126_off" data-id="126" data-set="ATG16L67" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off126" style="top:510px;left:403px;"> ATG16L</div> <div id="el126_ct" class="pw-tooltip" data-id="126"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el127_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray127 pw-gray" style="top:564px;left:430px;"> </div> <div id="el127_off" data-id="127" data-set="LC3-II68" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off127" style="top:564px;left:430px;"> </div> <div id="el127_ct" class="pw-tooltip" data-id="127"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el128_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray128 pw-gray" style="top:567px;left:397px;"> LC3-II </div> <div id="el128_off" data-id="128" data-set="LC3-II68" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off128" style="top:567px;left:397px;"> LC3-II</div> <div id="el128_ct" class="pw-tooltip" data-id="128"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el129_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray129 pw-gray" style="top:622px;left:450px;"> </div> <div id="el129_off" data-id="129" data-set="RB1CC169" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off129" style="top:622px;left:450px;"> </div> <div id="el129_ct" class="pw-tooltip" data-id="129"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=RB1CC1%2FFIP200">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el130_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray130 pw-gray" style="top:593px;left:394px;"> RB1CC1 </div> <div id="el130_off" data-id="130" data-set="RB1CC169" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off130" style="top:593px;left:394px;"> RB1CC1</div> <div id="el130_ct" class="pw-tooltip" data-id="130"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=RB1CC1%2FFIP200">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el131_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray131 pw-gray" style="top:619px;left:438px;"> </div> <div id="el131_off" data-id="131" data-set="ATG1370" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off131" style="top:619px;left:438px;"> </div> <div id="el131_ct" class="pw-tooltip" data-id="131"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG13">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el132_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray132 pw-gray" style="top:607px;left:393px;"> ATG13 </div> <div id="el132_off" data-id="132" data-set="ATG1370" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off132" style="top:607px;left:393px;"> ATG13</div> <div id="el132_ct" class="pw-tooltip" data-id="132"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG13">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el133_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray133 pw-gray" style="top:630px;left:441px;"> </div> <div id="el133_off" data-id="133" data-set="ULK271" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off133" style="top:630px;left:441px;"> </div> <div id="el133_ct" class="pw-tooltip" data-id="133"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK2">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el134_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray134 pw-gray" style="top:626px;left:395px;"> ULK2 </div> <div id="el134_off" data-id="134" data-set="ULK271" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off134" style="top:626px;left:395px;"> ULK2</div> <div id="el134_ct" class="pw-tooltip" data-id="134"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK2">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el135_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray135 pw-gray" style="top:641px;left:433px;"> </div> <div id="el135_off" data-id="135" data-set="ULK172" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off135" style="top:641px;left:433px;"> </div> <div id="el135_ct" class="pw-tooltip" data-id="135"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el136_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray136 pw-gray" style="top:640px;left:392px;"> ULK1 </div> <div id="el136_off" data-id="136" data-set="ULK172" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off136" style="top:640px;left:392px;"> ULK1</div> <div id="el136_ct" class="pw-tooltip" data-id="136"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ULK1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el137_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray137 pw-gray" style="top:647px;left:478px;"> </div> <div id="el137_off" data-id="137" data-set="ATG1273" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off137" style="top:647px;left:478px;"> </div> <div id="el137_ct" class="pw-tooltip" data-id="137"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el138_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray138 pw-gray" style="top:690px;left:449px;"> ATG12 </div> <div id="el138_off" data-id="138" data-set="ATG1273" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off138" style="top:690px;left:449px;"> ATG12</div> <div id="el138_ct" class="pw-tooltip" data-id="138"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg12">ATG12</a><br> </div> </div> <div id="el139_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray139 pw-gray" style="top:633px;left:471px;"> </div> <div id="el139_off" data-id="139" data-set="ATG574" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off139" style="top:633px;left:471px;"> </div> <div id="el139_ct" class="pw-tooltip" data-id="139"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el140_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray140 pw-gray" style="top:676px;left:442px;"> ATG5 </div> <div id="el140_off" data-id="140" data-set="ATG574" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off140" style="top:676px;left:442px;"> ATG5</div> <div id="el140_ct" class="pw-tooltip" data-id="140"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg5">ATG5</a><br> </div> </div> <div id="el141_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray141 pw-gray" style="top:621px;left:464px;"> </div> <div id="el141_off" data-id="141" data-set="ATG16L75" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off141" style="top:621px;left:464px;"> </div> <div id="el141_ct" class="pw-tooltip" data-id="141"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el142_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray142 pw-gray" style="top:662px;left:420px;"> ATG16L </div> <div id="el142_off" data-id="142" data-set="ATG16L75" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off142" style="top:662px;left:420px;"> ATG16L</div> <div id="el142_ct" class="pw-tooltip" data-id="142"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=ATG16L">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el143_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray143 pw-gray" style="top:652px;left:512px;"> </div> <div id="el143_off" data-id="143" data-set="GATE-16-II76" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off143" style="top:652px;left:512px;"> </div> <div id="el143_ct" class="pw-tooltip" data-id="143"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el144_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray144 pw-gray" style="top:670px;left:509px;"> GATE-16-II </div> <div id="el144_off" data-id="144" data-set="GATE-16-II76" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off144" style="top:670px;left:509px;"> GATE-16-II</div> <div id="el144_ct" class="pw-tooltip" data-id="144"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/gate-16">GATE-16</a><br> </div> </div> <div id="el145_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray145 pw-gray" style="top:592px;left:488px;"> </div> <div id="el145_off" data-id="145" data-set="WIPI1277" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off145" style="top:592px;left:488px;"> </div> <div id="el145_ct" class="pw-tooltip" data-id="145"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=WIPI1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el146_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray146 pw-gray" style="top:588px;left:509px;"> WIPI1/2 </div> <div id="el146_off" data-id="146" data-set="WIPI1277" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off146" style="top:588px;left:509px;"> WIPI1/2</div> <div id="el146_ct" class="pw-tooltip" data-id="146"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=WIPI1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el147_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray147 pw-gray" style="top:526px;left:488px;"> </div> <div id="el147_off" data-id="147" data-set="LC3-II78" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off147" style="top:526px;left:488px;"> </div> <div id="el147_ct" class="pw-tooltip" data-id="147"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el148_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray148 pw-gray" style="top:525px;left:509px;"> LC3-II </div> <div id="el148_off" data-id="148" data-set="LC3-II78" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off148" style="top:525px;left:509px;"> LC3-II</div> <div id="el148_ct" class="pw-tooltip" data-id="148"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el149_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-gray149 pw-gray" style="top:538px;left:494px;"> </div> <div id="el149_off" data-id="149" data-set="Adaptor79" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite el-off149" style="top:538px;left:494px;"> </div> <div id="el149_ct" class="pw-tooltip" data-id="149"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bnip3l">BNIP3L</a><br> </div> </div> <div id="el150_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-gray150 pw-gray" style="top:538px;left:516px;"> Adaptor </div> <div id="el150_off" data-id="150" data-set="Adaptor79" data-type="No Products Click" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label el-off150" style="top:538px;left:516px;"> Adaptor</div> <div id="el150_ct" class="pw-tooltip" data-id="150"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bnip3l">BNIP3L</a><br> </div> </div> <div id="el151_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label2 el-gray151 pw-gray" style="top:553px;left:521px;"> Cargo </div> <div id="el151_off" data-id="151" data-set="Cargo2" data-type="" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-label2 el-off151" style="top:553px;left:521px;"> Cargo</div> <div id="el151_ct" class="pw-tooltip" data-id="151"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el152_gry" class="autophagy_all autophagy_autophagosome pw-label2 el-gray152 pw-gray" style="top:739px;left:544px;"> Membrane Fusion </div> <div id="el152_off" data-id="152" data-set="MembraneFusion" data-type="" class="autophagy_all autophagy_autophagosome pw-label2 el-off152" style="top:739px;left:544px;"> Membrane Fusion</div> <div id="el152_ct" class="pw-tooltip" data-id="152"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el153_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray153 pw-gray" style="top:670px;left:344px;"> </div> <div id="el153_off" data-id="153" data-set="DFCP182" data-type="" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off153" style="top:670px;left:344px;"> </div> <div id="el153_ct" class="pw-tooltip" data-id="153"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DFCP1%2FZFYVE1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el154_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray154 pw-gray" style="top:688px;left:345px;"> DFCP1 </div> <div id="el154_off" data-id="154" data-set="DFCP182" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off154" style="top:688px;left:345px;"> DFCP1</div> <div id="el154_ct" class="pw-tooltip" data-id="154"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=DFCP1%2FZFYVE1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el155_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray155 pw-gray" style="top:599px;left:254px;"> </div> <div id="el155_off" data-id="155" data-set="ATG4B83" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off155" style="top:599px;left:254px;"> </div> <div id="el155_ct" class="pw-tooltip" data-id="155"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg4b">ATG4B</a><br> </div> </div> <div id="el156_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray156 pw-gray" style="top:602px;left:274px;"> ATG4B </div> <div id="el156_off" data-id="156" data-set="ATG4B83" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off156" style="top:602px;left:274px;"> ATG4B</div> <div id="el156_ct" class="pw-tooltip" data-id="156"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/atg4b">ATG4B</a><br> </div> </div> <div id="el157_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray157 pw-gray" style="top:576px;left:209px;"> </div> <div id="el157_off" data-id="157" data-set="LC3-I84" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off157" style="top:576px;left:209px;"> </div> <div id="el157_ct" class="pw-tooltip" data-id="157"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el158_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray158 pw-gray" style="top:578px;left:230px;"> LC3-I </div> <div id="el158_off" data-id="158" data-set="LC3-I84" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off158" style="top:578px;left:230px;"> LC3-I</div> <div id="el158_ct" class="pw-tooltip" data-id="158"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el159_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray159 pw-gray" style="top:611px;left:221px;"> </div> <div id="el159_off" data-id="159" data-set="LC3-II85" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off159" style="top:611px;left:221px;"> </div> <div id="el159_ct" class="pw-tooltip" data-id="159"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el160_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray160 pw-gray" style="top:614px;left:190px;"> LC3-II </div> <div id="el160_off" data-id="160" data-set="LC3-II85" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off160" style="top:614px;left:190px;"> LC3-II</div> <div id="el160_ct" class="pw-tooltip" data-id="160"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el161_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray161 pw-gray" style="top:659px;left:225px;"> </div> <div id="el161_off" data-id="161" data-set="LC3-II86" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off161" style="top:659px;left:225px;"> </div> <div id="el161_ct" class="pw-tooltip" data-id="161"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el162_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray162 pw-gray" style="top:659px;left:245px;"> LC3-II </div> <div id="el162_off" data-id="162" data-set="LC3-II86" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off162" style="top:659px;left:245px;"> LC3-II</div> <div id="el162_ct" class="pw-tooltip" data-id="162"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el163_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray163 pw-gray" style="top:671px;left:229px;"> </div> <div id="el163_off" data-id="163" data-set="Adaptor87" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off163" style="top:671px;left:229px;"> </div> <div id="el163_ct" class="pw-tooltip" data-id="163"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bnip3l">BNIP3L</a><br> </div> </div> <div id="el164_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray164 pw-gray" style="top:672px;left:249px;"> Adaptor </div> <div id="el164_off" data-id="164" data-set="Adaptor87" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off164" style="top:672px;left:249px;"> Adaptor</div> <div id="el164_ct" class="pw-tooltip" data-id="164"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/bnip3l">BNIP3L</a><br> </div> </div> <div id="el165_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label2 el-gray165 pw-gray" style="top:686px;left:254px;"> Cargo </div> <div id="el165_off" data-id="165" data-set="Cargo" data-type="" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label2 el-off165" style="top:686px;left:254px;"> Cargo</div> <div id="el165_ct" class="pw-tooltip" data-id="165"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el166_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray166 pw-gray" style="top:713px;left:228px;"> </div> <div id="el166_off" data-id="166" data-set="WIPI1289" data-type="" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off166" style="top:713px;left:228px;"> </div> <div id="el166_ct" class="pw-tooltip" data-id="166"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=WIPI1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el167_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray167 pw-gray" style="top:716px;left:248px;"> WIPI1/2 </div> <div id="el167_off" data-id="167" data-set="WIPI1289" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off167" style="top:716px;left:248px;"> WIPI1/2</div> <div id="el167_ct" class="pw-tooltip" data-id="167"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> We currently do not offer products for this molecule<br><br>Use our <a target="_blank" href="/products/product-suggestions?m=WIPI1">Product Suggestion form</a> to enter a request.<br><br>You will be notified once it becomes available. </div> </div> <div id="el168_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-gray168 pw-gray" style="top:763px;left:241px;"> </div> <div id="el168_off" data-id="168" data-set="LC3-II90" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite el-off168" style="top:763px;left:241px;"> </div> <div id="el168_ct" class="pw-tooltip" data-id="168"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el169_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-gray169 pw-gray" style="top:767px;left:262px;"> LC3-II </div> <div id="el169_off" data-id="169" data-set="LC3-II90" data-type="No Products Click" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label el-off169" style="top:767px;left:262px;"> LC3-II</div> <div id="el169_ct" class="pw-tooltip" data-id="169"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> <a target="_blank" href="/target/lc3-map1lc3a">LC3/MAP1LC3A</a><br> </div> </div> <div id="el170_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label2 el-gray170 pw-gray" style="top:731px;left:115px;"> Autophagosome </div> <div id="el170_off" data-id="170" data-set="Autophagosome" data-type="" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-label2 el-off170" style="top:731px;left:115px;"> Autophagosome</div> <div id="el170_ct" class="pw-tooltip" data-id="170"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el171_gry" class="autophagy_all autophagy_autolysosome pw-label2 el-gray171 pw-gray" style="top:647px;left:48px;"> Lysosome </div> <div id="el171_off" data-id="171" data-set="Lysosome" data-type="" class="autophagy_all autophagy_autolysosome pw-label2 el-off171" style="top:647px;left:48px;"> Lysosome</div> <div id="el171_ct" class="pw-tooltip" data-id="171"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el172_gry" class="autophagy_all autophagy_autolysosome pw-label2 el-gray172 pw-gray" style="top:521px;left:37px;"> Autolysosome </div> <div id="el172_off" data-id="172" data-set="Autolysosome" data-type="" class="autophagy_all autophagy_autolysosome pw-label2 el-off172" style="top:521px;left:37px;"> Autolysosome</div> <div id="el172_ct" class="pw-tooltip" data-id="172"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el173_gry" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite pw-sprite-inactive el-gray173 pw-gray" style="top:683px;left:234px;"> </div> <div id="el173_off" data-id="173" data-set="Cargo" data-type="" class="autophagy_all autophagy_autophagosome autophagy_autolysosome pw-sprite pw-sprite-inactive el-off173" style="top:683px;left:234px;"> </div> <div id="el173_ct" class="pw-tooltip" data-id="173"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> <div id="el174_gry" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite pw-sprite-inactive el-gray174 pw-gray" style="top:550px;left:501px;"> </div> <div id="el174_off" data-id="174" data-set="Cargo2" data-type="" class="autophagy_all autophagy_elongation autophagy_autophagosome pw-sprite pw-sprite-inactive el-off174" style="top:550px;left:501px;"> </div> <div id="el174_ct" class="pw-tooltip" data-id="174"> <div class="pw-tooltip-head">Products<a href="#">Close</a></div> <div class="pw-tooltip-inner"> </div> </div> </div> <div id="pw-img"> <img id="cont-img" src="https://resources.rndsystems.com/images/Pathways/pathway-images/autophaghy_all.png" alt="Autophagy Pathway" style="height:876px"> </div> </div> <div id="pathway-description"><h2>Overview of Autophagy Pathways</h2><p><p>Macroautophagy, hereafter referred to as autophagy, is a catabolic process by which cells degrade long-lived proteins, organelles, and certain types of bacteria via lysosomes. Briefly, the autophagy pathway entails the development of a phagophore that envelopes cytoplasmic components and forms a double-membrane autophagosome that subsequently fuses with a lysosome for the digestion of its contents. Of importance to a wide range of researchers, the autophagy pathway is thought to be protective against several diseases, including neurodegeneration, myopathy, liver disease, and diabetes. Additionally, autophagy appears to have a complex role in cancer, as it has been reported to both promote and inhibit cancer.<p> <p>Autophagy is initiated by the generation of phosphatidylinositol 3-phosphate [PI(3)P]-rich regions of the endoplasmic reticulum (ER) that form phagophores, which are also referred to as omegasomes due to their shape. PI(3)P is generated by hVps34, the catalytic subunit of the Beclin 1 complex, and is required for the recruitment of downstream autophagy components, such as WIPI1/2 and DFCP1. The ULK1/2 kinase complex, including ULK1, ULK2, ATG13, and RB1CC1, is also required for autophagy initiation. It positively regulates the Beclin 1 complex indirectly by promoting its release from microtubules and possibly directly by phosphorylating Beclin 1 and stimulating hVps34 activity.</p> <p>Phagophore elongation is thought to require mATG9 and the Ubiquitin-like protein, LC3. mATG9 is a transmembrane protein found mainly in the Golgi network that transiently interacts with phagophores in an ULK1-dependent manner during nutrient starvation. These transient interactions may contribute to membrane delivery during phagophore elongation. LC3 is converted to LC3-II, which is commonly used as an autophagy marker, in two steps. LC3 is first cleaved by ATG4B to form LC3-I. LC3-I is then translocated to phagophores via the Ubiquitin-activating (E1)-like enzyme ATG7 and the Ubiquitin-conjugating (E2)-like enzyme ATG3 where it is conjugated to phosphatidylethanolamine (PE) to form LC3-II. LC3-II formation is positively regulated by PI(3)P effector proteins, such as WIPI1/2, and the ATG16L-ATG5-ATG12 Ubiquitin-like complex. Interestingly, RB1CC1 may interact with ATG16L, which suggests that the ULK1/2 kinase complex might also function during phagophore elongation. LC3-II also binds substrates for autophagic degradation, referred to as cargo, via different adaptor proteins. For example, during mitochondrial autophagy, or mitophagy, LC3-II binds to mitochondria via the BNIP3L adaptor protein.</p> Autophagosome formation occurs via the fusion of the phagophore double membranes into a sphere, but the mechanism by which this happens is not understood. GATE-16, which is closely related to LC3 and processed in a very similar manner to LC3, is only required for later stages of autophagosome maturation and might have a role in membrane fusion. Autolysosomal degradation is initiated when the autophagosome fuses with a lysosome, resulting in the disruption of the inner membrane and the digestion of its contents. LC3-II that is on the cytoplasmic side of the outer membrane avoids degradation and can be recycled via cleavage by ATG4B.</p> <p>To learn more, please visit our <a href="https://www.rndsystems.com/research-area/autophagy">Autophagy Research Area</a>.</p></p></div> <div id="print-copy-form" class="accordion-wrapper"> <h3 class="builder-header builder-bead-type ui-accordion-header ui-helper-reset ui-state-default ui-corner-all ui-accordion-icons" data-toggle="collapse" data-target="#collapsePathwayRequest" aria-expanded="false" id="pathwayRequestAccordionHeader"> <span class="ui-accordion-header-icon" id="accordionArrow"></span> Get Print Copy of this Pathway </h3> <div class="collapse" id="collapsePathwayRequest"> <div id="pathwayRequestWebformWrapper"> <form class="webform-client-form webform-client-form-27981" action="/pathways/autophagy-pathway" method="post" id="webform-client-form-27981" accept-charset="UTF-8"><div><div class="form-item webform-component 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and Barbuda</option><option value="AR">Argentina</option><option value="AM">Armenia</option><option value="AW">Aruba</option><option value="AU">Australia</option><option value="AT">Austria</option><option value="AZ">Azerbaijan</option><option value="BS">Bahamas</option><option value="BH">Bahrain</option><option value="BD">Bangladesh</option><option value="BB">Barbados</option><option value="BE">Belgium</option><option value="BZ">Belize</option><option value="BJ">Benin</option><option value="BM">Bermuda</option><option value="BO">Bolivia</option><option value="BA">Bosnia and Herzegovina</option><option value="BW">Botswana</option><option value="BR">Brazil</option><option value="BN">Brunei</option><option value="BG">Bulgaria</option><option value="BF">Burkina Faso</option><option value="BI">Burundi</option><option value="KH">Cambodia</option><option value="CM">Cameroon</option><option value="CA">Canada</option><option value="KY">Cayman Islands</option><option value="CF">Central African 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value="NP">Nepal</option><option value="NL">Netherlands</option><option value="AN">Netherlands Antilles</option><option value="NC">New Caledonia</option><option value="NZ">New Zealand</option><option value="NI">Nicaragua</option><option value="NE">Niger</option><option value="NG">Nigeria</option><option value="MP">Northern Mariana Islands</option><option value="NO">Norway</option><option value="OM">Oman</option><option value="PK">Pakistan</option><option value="PW">Palau</option><option value="PA">Panama</option><option value="PG">Papua New Guinea</option><option value="PY">Paraguay</option><option value="PE">Peru</option><option value="PH">Philippines</option><option value="PL">Poland</option><option value="PT">Portugal</option><option value="PR">Puerto Rico</option><option value="QA">Qatar</option><option value="RO">Romania</option><option value="RW">Rwanda</option><option value="KN">Saint Kitts and Nevis</option><option value="LC">Saint Lucia</option><option value="MF">Saint Martin 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