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Search results for: ethanolic extract
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text-center" style="font-size:1.6rem;">Search results for: ethanolic extract</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2121</span> Antimycobacterial Activity of Ethanolic Extract of Artemisia absinthium</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=T.%20Hojageldiyev">T. Hojageldiyev</a>, <a href="https://publications.waset.org/abstracts/search?q=Y.%20Bolmammedov"> Y. Bolmammedov</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Gurbanaliyev"> S. Gurbanaliyev</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It is known that drugs used in the treatment of tuberculosis show toxic effect to organism especially to liver besides its therapeutic effect. Because of ineffectiveness of drugs used in the treatment regimen of tuberculosis against multidrug resistance (MDR) and extensively drug-resistance (XDR) tuberculosis requires the development of new treatment methods and new, novel drugs. Considering the usage of Artemisia absinthium in traditional medicine in treatment of wounds which suggests its antibacterial activity it seems that, also it may have significant antimycobacterial activity. The objective of present study was to evaluate antibacterial activity of ethanolic extract of A. absinthium against M. tuberculosis. In this study, the effect of ethanolic extract of A. absinthium was tested against tuberculosis and pharmaco-toxicological properties evaluated on laboratory animals. The 20%, 40%, 70% and 96% ethanolic extracts of A. absinthium prepared then its bacteriostatic and bactericidal activities were evaluated by validated methods. Data were analyzed by GraphPad Prism 7.0 at the level P < 0.05. Results showed that ethanolic extracts of A. absinthium show no toxicological properties with having high LD50. All concentrations of extract show high bacteriostatic activity on M. tuberculosis. 96% ethanolic extract has highest bactericidal effect among other concentrations. By conducting further studies, as a result of our study, antimycobacterial drug can be prepared from A. absinthium. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Artemisia%20absinthium" title="Artemisia absinthium">Artemisia absinthium</a>, <a href="https://publications.waset.org/abstracts/search?q=antimycobacterial" title=" antimycobacterial"> antimycobacterial</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract" title=" ethanolic extract"> ethanolic extract</a>, <a href="https://publications.waset.org/abstracts/search?q=Mycobacteria%20tuberculosis" title=" Mycobacteria tuberculosis"> Mycobacteria tuberculosis</a> </p> <a href="https://publications.waset.org/abstracts/99711/antimycobacterial-activity-of-ethanolic-extract-of-artemisia-absinthium" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99711.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">292</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2120</span> Preliminary Phytochemical Screening of Eucalyptus camaldulensis Leaves, Stem-Bark, Root, Fruits, and Seeds and Ethanolic Extracts</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Sani">I. Sani</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Bello"> F. Bello</a>, <a href="https://publications.waset.org/abstracts/search?q=Isah%20M.%20Fakai"> Isah M. Fakai</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Abdulhamid"> A. Abdulhamid</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Phytochemicals are active secondary plant metabolites responsible for most of the claimed medicinal activities of plants. Eucalyptus camaldulensis is one of those plants that possess these phytochemicals and claimed to possess medicinal activities on various ailments. The phytochemicals constituents of various parts of this plant were investigated using standard methods of phytochemicals screening in both aqueous and ethanolic extracts. Qualitative screening revealed that tannins, saponins, glycosides, steroids, and anthraquinones were present in aqueous extract of all the parts of the plant, whereas alkaloids, flavonoids and terpenoids were absent. On the other hand, tannins and steroids were present in the ethanolic extract of all the parts of the plant, while saponins, alkaloids, flavonoids and terpenoids were present only in some parts of the plant. However, glycosides and anthraquinone were absent in all the ethanolic extracts. The quantitative screening revealed large amount of saponins in both aqueous and ethanolic extracts across the various parts of the plant. Whereas small amount of tannins, alkaloids and flavonoids were found only in the ethanolic extract of some parts of the plant. The presence of these phytochemicals in Eucalyptus camaldulensis could therefore justify the applications of the plant in management and curing of various ailments as claimed traditionally. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eucalyptus%20camaldulensis" title="Eucalyptus camaldulensis">Eucalyptus camaldulensis</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20screening" title=" phytochemical screening"> phytochemical screening</a>, <a href="https://publications.waset.org/abstracts/search?q=aqueous%20extract" title=" aqueous extract"> aqueous extract</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract" title=" ethanolic extract"> ethanolic extract</a> </p> <a href="https://publications.waset.org/abstracts/15769/preliminary-phytochemical-screening-of-eucalyptus-camaldulensis-leaves-stem-bark-root-fruits-and-seeds-and-ethanolic-extracts" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/15769.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">383</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2119</span> Eucalyptus camaldulensis: Phytochemical Composition of Ethanolic and Aqueous Extracts of the Leaves, Stem-Bark, Root, Fruits, and Seeds </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20Sani">I. Sani</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Abdulhamid"> A. Abdulhamid</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Bello"> F. Bello</a>, <a href="https://publications.waset.org/abstracts/search?q=Isah%20M.%20Fakai"> Isah M. Fakai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Phytochemicals are active secondary plant metabolites responsible for most of the claimed medicinal activities of plants. Eucalyptus camaldulensis is one of those plants that possess these phytochemicals and claimed to possess medicinal activities on various ailments. The phytochemicals constituents of various parts of this plant were investigated using standard methods of phytochemicals screening in both aqueous and ethanolic extracts. Qualitative screening revealed that tannins, saponins, glycosides, steroids and anthraquinones were present in aqueous extract of all the parts of the plant, whereas alkaloids, flavonoids and terpenoids were absent. On the other hand, tannins and steroids were present in the ethanolic extract of all the parts of the plant, while saponins, alkaloids, flavonoids and terpenoids were present only in some parts of the plant. However, glycosides and anthraquinone were absent in all the ethanolic extracts. The quantitative screening revealed large amount of saponins in both aqueous and ethanolic extracts across the various parts of the plant. Whereas small amount of tannins, alkaloids and flavonoids were found only in the ethanolic extract of some parts of the plant. The presence of these phytochemicals in Eucalyptus camaldulensis could therefore justify the applications of the plant in management and curing of various ailments as claimed traditionally. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Eucalyptus%20camaldulensis" title="Eucalyptus camaldulensis">Eucalyptus camaldulensis</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20Screening" title=" phytochemical Screening"> phytochemical Screening</a>, <a href="https://publications.waset.org/abstracts/search?q=aqueous%20extract" title=" aqueous extract"> aqueous extract</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract" title=" ethanolic extract"> ethanolic extract</a> </p> <a href="https://publications.waset.org/abstracts/17776/eucalyptus-camaldulensis-phytochemical-composition-of-ethanolic-and-aqueous-extracts-of-the-leaves-stem-bark-root-fruits-and-seeds" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17776.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">551</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2118</span> Aphrodisiac Activity of Ethanolic Extract of Ionidium Suffruticosum in Male Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=D.%20Satheesh%20Kumar">D. Satheesh Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20S.%20Lakshmi"> K. S. Lakshmi</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20J.%20Vishnu%20Varthan"> V. J. Vishnu Varthan </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Aphrodisiacs are the substances which are used to increase sexual activity and help in fertility. Infertility is a worldwide medical and social problem. Ionidium suffruticosum has an extensive ethnomedical history of use as a traditional remedy for reproductive impairments. Hence, this study was conducted to study the aphrodisiac properties of Ionidium suffruticosum by observing the sexual behavior of male rats. Methods: The ethanolic extract of whole plant of Ionidium suffruticosum (EEIS) at the dose of 200 mg/kg and sildenafil citrate at the dose of 5 mg/kg were administered to the male rats. Mount latency (ML), intromission latency (IL), ejaculation latency (EL), mounting frequency (MF), intromission frequency (IF), ejaculation frequency (EF) and post-ejaculatory interval (PEI) were the parameters observed before and during the sexual behaviour study at days 0, 10, 20, 30, and 40. Results: The ethanolic extract of roots of Ionidium suffruticosum reduced significantly ML, IL, EL and PEI (p<0.05). There was statistically increase in MF, IF and EF (p<0.05) compared to control following treatment with ethanolic extract of Ionidium suffruticosum. These effects were observed in sexually active and inactive male rats. Conclusion: Present findings provide experimental evidence that the crude extract of Ionidium suffruticosum, used as a traditional remedy, possesses aphrodisiac properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ionidium%20suffruticosum" title="Ionidium suffruticosum">Ionidium suffruticosum</a>, <a href="https://publications.waset.org/abstracts/search?q=aphrodisiac" title=" aphrodisiac"> aphrodisiac</a>, <a href="https://publications.waset.org/abstracts/search?q=sexual%20behavior" title=" sexual behavior"> sexual behavior</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract" title=" ethanolic extract"> ethanolic extract</a> </p> <a href="https://publications.waset.org/abstracts/25508/aphrodisiac-activity-of-ethanolic-extract-of-ionidium-suffruticosum-in-male-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25508.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">418</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2117</span> Protective Effects of Ethanolic Purslane Extracts on Doxorubicin-Induced Hepatotoxicity in Albino Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Osama%20M.%20Ahmed">Osama M. Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Walaa%20G.%20Hozayen"> Walaa G. Hozayen</a>, <a href="https://publications.waset.org/abstracts/search?q=Haidy%20Tamer%20Abo%20Sree"> Haidy Tamer Abo Sree</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The effect of doxorubicin (4 mg/kg b.w.week) without or with oral administration of ethanolic purslane (Portulaca oleracea) shoot (leaves and stems) extract (50 mg/kg b.w.day) or ethanolic purslane seeds extract (50 mg/kg b.w.day) co-treatments for 6 weeks was evaluated in adult male rats. There was an increase in serum levels of ALT, AST, ALP, GGT and total bilirubin. In addition, hepatic glutathine, glutathione transferase, peroxidase, SOD, CAT activities were decreased while lipid peroxidation in the liver was increased. Co-administration of ethanolic purslane and seed extracts successfully improved the adverse changes in the liver functions with an increase in antioxidants activities and reduction of lipid peroxidation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidants" title="antioxidants">antioxidants</a>, <a href="https://publications.waset.org/abstracts/search?q=doxorubicin" title=" doxorubicin"> doxorubicin</a>, <a href="https://publications.waset.org/abstracts/search?q=hepatotoxicity" title=" hepatotoxicity"> hepatotoxicity</a>, <a href="https://publications.waset.org/abstracts/search?q=purslane" title=" purslane"> purslane</a> </p> <a href="https://publications.waset.org/abstracts/30941/protective-effects-of-ethanolic-purslane-extracts-on-doxorubicin-induced-hepatotoxicity-in-albino-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30941.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">418</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2116</span> Evaluation of Moroccan Microalgae Spirulina platensis as a Potential Source of Natural Antioxidants</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=T.%20Ould%20Bellahcen">T. Ould Bellahcen</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Amiri"> A. Amiri</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20Touam"> I. Touam</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Hmimid"> F. Hmimid</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20El%20Amrani"> A. El Amrani</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Cherki"> M. Cherki </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The antioxidant activity of three extracts (water, lipidic and ethanolic) prepared from the microalgae Spirulina platensis isolated from Moroccan lake, using 2, 2 diphenyl-1-picrylhydrazyl (DPPH) and 2,2’-azino-bis ethylbenzthiazoline-6-sulfonic acid (ABTS) radical assay, was studied and compared. The obtained results revealed that the IC₅₀ found using DPPH were lower than that of ABTS for all extracts from these planktonic blue-green algae. The high levels of phenolic and flavonoid content were found in the ethanolic extract 0,33 ± 0,01 mg GAE/g dw and 0,21 ± 0,01 mg quercetin/g dw respectively. In addition, using DPPH, the highest activity with IC₅₀ = 0,449 ± 0,083 mg/ml, was found for the ethanolic extract, followed by that of lipidic extract (IC₅₀ = 0,491 ± 0,059 mg/ml). The lowest activity was for the aqueous extract (IC₅₀ = 4,148 ± 0,132 mg/ml). For ABTS, the highest activity was observed for the lipidic extract with IC₅₀ = 0,740 ± 0,012 mg/ml, while, the aqueous extract recorded the lowest activity (IC₅₀ = 6,914 ± 0, 0067 mg/ml). A moderate activity was showed for the ethanolic extract (IC₅₀ = 5,852 ± 0, 0171 mg/ml). It can be concluded from this first study that Spirulina platensis extracts show an interesting antioxidant and antiradicals properties suggesting that this alga could be used as a potential source of antioxidants. A qualitative and quantitative analysis of polyphenol and flavonoids in the extracts using HPLC is in progress so as to study the correlation between the antioxidant activity and chemical composition. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Spirulina%20platensis" title="Spirulina platensis">Spirulina platensis</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=DPPH" title=" DPPH"> DPPH</a>, <a href="https://publications.waset.org/abstracts/search?q=ABTS" title=" ABTS"> ABTS</a> </p> <a href="https://publications.waset.org/abstracts/95749/evaluation-of-moroccan-microalgae-spirulina-platensis-as-a-potential-source-of-natural-antioxidants" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/95749.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">165</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2115</span> Lc-Ms N-Alkylamide Profiling of an Ethanolic Anacyclus pyrethrum Root Extract</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vikas%20Sharma">Vikas Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20K.%20Dixit"> V. K. Dixit</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The roots of Anacyclus pyrethrum DC (AP) (Asteraceae) are frequently used in traditional medicine as Vajikarana Rasayana. An ethanolic extract of root of Anacyclus pyrethrum demonstrated its potential to enhance the sexual behaviour of male rats, with a dose dependent effect on sperm count and androgens concentration. Phytochemical analysis of ethanolic extract of Anacyclus pyrethrum revealed that it is rich in N-alkylamide. This study therefore sought to assess characterization of ethanolic extract of Anacyclus pyrethrum root. Root extract was performed using a gradient reversed phase high performance liquid chromatography/UV/electrospray ionization ion trap mass spectrometry (HPLC/ESI-MS) method on an embedded polar column. MS1 and MS2 fragmentation data were used for identification purposes, while UV was used for quantification. Thirteen N-alkylamides (five N-isobutylamides, three N-methyl isobutylamides, four tyramides, and one 2-phenylethylamide) were detected. Five of them identified as undeca-2E,4E-diene-8,10-diynoic acid N-methyl isobutylamide, tetradeca-2E,4E-diene-8,10-diynoic acid tyramide, deca-2E,4E-dienoic acid N-methyl isobutylamide, tetradeca-2E,4E,XE/Z-trienoic acid tyramide and tetradeca-2E,4E,8Z,10Z-tetraenoic isobutylamide are novel compounds, which have never been identified in Anacyclus pyrethrum. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anacyclus%20pyrethrum%20%28Asteraceae%29" title="Anacyclus pyrethrum (Asteraceae)">Anacyclus pyrethrum (Asteraceae)</a>, <a href="https://publications.waset.org/abstracts/search?q=LC-MS%20plant%20profiling" title=" LC-MS plant profiling"> LC-MS plant profiling</a>, <a href="https://publications.waset.org/abstracts/search?q=N-alkylamides" title=" N-alkylamides"> N-alkylamides</a>, <a href="https://publications.waset.org/abstracts/search?q=pellitorine" title=" pellitorine"> pellitorine</a>, <a href="https://publications.waset.org/abstracts/search?q=anacycline" title=" anacycline"> anacycline</a> </p> <a href="https://publications.waset.org/abstracts/30518/lc-ms-n-alkylamide-profiling-of-an-ethanolic-anacyclus-pyrethrum-root-extract" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30518.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">402</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2114</span> Antimicrobial Activity of Some Alimentary and Medicinal Plants</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Akrpoum%20Souad">Akrpoum Souad</a>, <a href="https://publications.waset.org/abstracts/search?q=Lalaoui%20Korrichi"> Lalaoui Korrichi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Vicia faba L.,Vaccinium macrocarpon, Punica granatum, Lavandula officinalis, Artemisia absinthium, Linum capitatum and Camellia sinensis were frequently used in our alimentation. In this study, we have tested the antimicrobial activity of their ethanolic and methanolic extracts on some pathogen bacteria, then their ability to in vivo inhibit the growth of Strepcoccus pneumonia. The phytochemical screening has given the composition of the most active extracts. According to the obtained results, the ethanolic extract of Lavendula. officinalis and A absinthium has shown an inhibition of all the tested strains of becteria3. The ethanolic extract of L. officinalis has given the highest activity against S. pneumoniae, followed by the methanolic extract of C. sinensis 1, 2 and P. granatum. The phytochemical screening showed that the most active extracts contained mainly naturels compounds. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=plants" title="plants">plants</a>, <a href="https://publications.waset.org/abstracts/search?q=extracts" title=" extracts"> extracts</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activity" title=" antimicrobial activity"> antimicrobial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=streptococcus%20pneumoniae" title=" streptococcus pneumoniae"> streptococcus pneumoniae</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20screening" title=" phytochemical screening"> phytochemical screening</a> </p> <a href="https://publications.waset.org/abstracts/27762/antimicrobial-activity-of-some-alimentary-and-medicinal-plants" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/27762.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">517</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2113</span> In Vitro Antioxidant and Cytotoxic Activities Against Human Oral Cancer and Human Laryngeal Cancer of Limonia acidissima L. Bark Extracts</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kriyapa%20lairungruang">Kriyapa lairungruang</a>, <a href="https://publications.waset.org/abstracts/search?q=Arunporn%20Itharat"> Arunporn Itharat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Limonia acidissima L. (LA) (Common name: wood apple, Thai name: ma-khwit) is a medicinal plant which has long been used in Thai traditional medicine. Its bark is used for treatment of diarrhea, abscess, wound healing and inflammation and it is also used in oral cancer. Thus, this research aimed to investigate antioxidant and cytotoxic activities of the LA bark extracts produced by various extraction methods. Different extraction procedures were used to extract LA bark for biological activity testing: boiling in water, maceration with 95% ethanol, maceration with 50% ethanol and water boiling of each the 95% and the 50% ethanolic residues. All extracts were tested for antioxidant activity using DPPH radical scavenging assay, cytotoxic activity against human laryngeal epidermoid carcinoma (HEp-2) cells and human oral epidermoid carcinoma (KB) cells using sulforhodamine B (SRB) assay. The results found that the 95% ethanolic extract of LA bark showed the highest antioxidant activity with EC50 values of 29.76±1.88 µg/ml. For cytotoxic activity, the 50% ethanolic extract showed the best cytotoxic activity against HEp-2 and KB cells with IC50 values of 9.55±1.68 and 18.90±0.86 µg/ml, respectively. This study demonstrated that the 95% ethanolic extract of LA bark showed moderate antioxidant activity and the 50% ethanolic extract provided potent cytotoxic activity against HEp-2 and KB cells. These results confirm the traditional use of LA for the treatment of oral cancer and laryngeal cancer, and also support its ongoing use. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title="antioxidant activity">antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=cytotoxic%20activity" title=" cytotoxic activity"> cytotoxic activity</a>, <a href="https://publications.waset.org/abstracts/search?q=Laryngeal%20epidermoid%20carcinoma" title=" Laryngeal epidermoid carcinoma"> Laryngeal epidermoid carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=Limonia%20acidissima%20L." title=" Limonia acidissima L."> Limonia acidissima L.</a>, <a href="https://publications.waset.org/abstracts/search?q=oral%20epidermoid%20carcinoma" title=" oral epidermoid carcinoma"> oral epidermoid carcinoma</a> </p> <a href="https://publications.waset.org/abstracts/25184/in-vitro-antioxidant-and-cytotoxic-activities-against-human-oral-cancer-and-human-laryngeal-cancer-of-limonia-acidissima-l-bark-extracts" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25184.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">478</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2112</span> Camel Thorn Has Hepatoprotective Activity Against Carbon Tetrachloride or Acetaminophen-Induced Hepatotoxicity but Enhances the Cardiac Toxicity of Adriamycin in Rodents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Awad%20G.%20Abdellatif">Awad G. Abdellatif</a>, <a href="https://publications.waset.org/abstracts/search?q=Huda%20M.%20Gargoum"> Huda M. Gargoum</a>, <a href="https://publications.waset.org/abstracts/search?q=Abdelkader%20A.%20Debani"> Abdelkader A. Debani</a>, <a href="https://publications.waset.org/abstracts/search?q=Mudafara%20Bengleil"> Mudafara Bengleil</a>, <a href="https://publications.waset.org/abstracts/search?q=Salmin%20Alshalmani"> Salmin Alshalmani</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20El%20Zuki"> N. El Zuki</a>, <a href="https://publications.waset.org/abstracts/search?q=Omran%20El%20Fitouri"> Omran El Fitouri</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the administration of 660 mg/kg of the ethanolic extract of the Alhgigraecorum (camel thorn) to mice, showed a significant decrease in the level of transaminases in animals treated with a combination of CTE plus carbon tetrachloride (CCl4) or acetaminophen as compared to animals receiving CCl4 or acetaminophen alone. The histopathological investigation also confirmed that camel thorn extract protects the liver against damage-induced either by carbon tetrachloride or acetaminophen. On the other hand, the cardiac toxicity produced by adriamycin was significantly increased in the presence of the ethanolic extract of camel thorn. Our study suggested that camel thorn can protect the liver against the injury produced by carbon tetrachloride or acetaminophen, with an unexpected increase in the cardiac toxicity–induced by adriamycin in rodents. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ethanolic" title="ethanolic">ethanolic</a>, <a href="https://publications.waset.org/abstracts/search?q=alhgigraecorum" title=" alhgigraecorum"> alhgigraecorum</a>, <a href="https://publications.waset.org/abstracts/search?q=tetrachloride" title=" tetrachloride"> tetrachloride</a>, <a href="https://publications.waset.org/abstracts/search?q=acetaminophen" title=" acetaminophen"> acetaminophen</a> </p> <a href="https://publications.waset.org/abstracts/4025/camel-thorn-has-hepatoprotective-activity-against-carbon-tetrachloride-or-acetaminophen-induced-hepatotoxicity-but-enhances-the-cardiac-toxicity-of-adriamycin-in-rodents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/4025.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">502</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2111</span> Evaluation of Excision Wound Healing Activity of Ethanolic Extract of Michelia Champaca ın Diabetic Wistar Rats </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Smita%20Shenoy">Smita Shenoy</a>, <a href="https://publications.waset.org/abstracts/search?q=Amoolya%20Gowda"> Amoolya Gowda</a>, <a href="https://publications.waset.org/abstracts/search?q=Tara%20Shanbhag"> Tara Shanbhag</a>, <a href="https://publications.waset.org/abstracts/search?q=Krishnananda%20Prabhu"> Krishnananda Prabhu</a>, <a href="https://publications.waset.org/abstracts/search?q=Venumadhav%20Nelluri"> Venumadhav Nelluri </a> </p> <p class="card-text"><strong>Abstract:</strong></p> The study was undertaken to assess the effect of ethanolic extract of Michelia champaca on excision wound healing in diabetic wistar rats. Excision wound was made in five groups of rats after inducing diabetes with streptozotocin in four groups. Paraffin was applied to wounds in nondiabetic and diabetic control and 2.5%, 5%, 10% ointment of extract to wounds in three diabetic test groups. Monitoring of wound contraction rate, the period of epithelization and histopathological examination of granulation tissue was done. There was a significant (p < 0.05) decrease in the period of epithelization and a significant increase in the wound contraction rate on day 12 and 16 in rats treated with 5% and 10% ointment as compared to diabetic rats. There was a better organization of collagen fibers in the granulation tissue of wounds treated with 10% ointment. The higher dose of ethanolic extract of Michelia champaca promoted wound healing in diabetic Wistar rats. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Michelia%20champaca" title="Michelia champaca">Michelia champaca</a>, <a href="https://publications.waset.org/abstracts/search?q=excision%20wound" title=" excision wound"> excision wound</a>, <a href="https://publications.waset.org/abstracts/search?q=contraction" title=" contraction"> contraction</a>, <a href="https://publications.waset.org/abstracts/search?q=epithelization" title=" epithelization"> epithelization</a> </p> <a href="https://publications.waset.org/abstracts/1352/evaluation-of-excision-wound-healing-activity-of-ethanolic-extract-of-michelia-champaca-in-diabetic-wistar-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/1352.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">359</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2110</span> Phytochimical Screening and Antimicrobial Activity of Ethanolic Extract of Solenostemma Argel (Asclepiadaceae)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fatma%20Acheuk">Fatma Acheuk</a>, <a href="https://publications.waset.org/abstracts/search?q=Akila%20Hamichi"> Akila Hamichi</a>, <a href="https://publications.waset.org/abstracts/search?q=Siham%20Semmar"> Siham Semmar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The crude ethanolic extract from Solenostemma argel was obtained by maceration of leaves and stems of the plant. Phytochimical study revealed the richness of the species on flavonoids, alkaloids, tannins and glycosides. Antimicrobial activity of the growth of clinical isolates of Eschirichia coli, Pseudomonas aeriginosa, Staphylococus aureus and Bacillus Subtilis was carried out using agar disc diffusion. The results of the study revealed that the test compound has antimicrobial activity against gram-positive bacteria which are resistant to commonly antimicrobial agents used. However, no effect was observed on other species tested. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Solenostemma%20argel" title="Solenostemma argel">Solenostemma argel</a>, <a href="https://publications.waset.org/abstracts/search?q=crude%20extract" title=" crude extract"> crude extract</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20screening" title=" phytochemical screening"> phytochemical screening</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activity" title=" antimicrobial activity "> antimicrobial activity </a> </p> <a href="https://publications.waset.org/abstracts/37158/phytochimical-screening-and-antimicrobial-activity-of-ethanolic-extract-of-solenostemma-argel-asclepiadaceae" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37158.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">381</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2109</span> The Anti-Allergic Activity of Prasaprohyai Preparation Extract after Accelerated Stability Testing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sunita%20Makchuchit">Sunita Makchuchit</a>, <a href="https://publications.waset.org/abstracts/search?q=Arunporn%20Itharat"> Arunporn Itharat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Prasaprohyai, a Thai traditional medicine preparation listed in the Thai National List of Essential Medicines, is commonly used for treatment of fever and colds. Prasaprohyai preparation consists of 21 different plants, with Kaempferia galanga (50% w/w) as the main ingredient. The objective of this study was to investigate the anti-allergic activity of the crude extract from Prasaprohyai after accelerated stability test procedure. The method of extract used maceration in 95% ethanol and the crude extract was kept under accelerated condition at 40 ± 2 oC and 75 ± 5% relative humidity (RH) for six months. After six months of storage at 40 oC, the crude sample in various storage times (0, 15, 30, 45, 60, 90, 120, 150 and 180 days) were investigated for anti-allergic activity using IgE-sensitized RBL-2H3 cell lines. The results showed that the stability of crude ethanolic extract from Prasaprohyai under accelerated testing had no significant effect of anti-allergic activity when compared with day 0. The results showed that the ethanolic extract could be stored for two years at room temperature without loss of activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=accelerated%20stability" title="accelerated stability">accelerated stability</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-allergy" title=" anti-allergy"> anti-allergy</a>, <a href="https://publications.waset.org/abstracts/search?q=prasaprohyai" title=" prasaprohyai"> prasaprohyai</a>, <a href="https://publications.waset.org/abstracts/search?q=RBL-2H3%20cell%20lines" title=" RBL-2H3 cell lines"> RBL-2H3 cell lines</a> </p> <a href="https://publications.waset.org/abstracts/25233/the-anti-allergic-activity-of-prasaprohyai-preparation-extract-after-accelerated-stability-testing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25233.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">489</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2108</span> Mechanism of in Vitro Inhibition of Alpha-Amylase, Alpha-Glucosidase by Ethanolic Extracts of Polyalthia Longifolia, Its in Vitro Cytotoxicity on L6, Vero Cell-Lines and Influence of Glucose Uptake by Rat Hemi-Diaphragm</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=P.%20Gayathri">P. Gayathri</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20P.%20Jeyanthi"> G. P. Jeyanthi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The bark of Polyalthia longifolia is used in ayurvedic system of medicine for the manangement of various ailments including diabetes mellitus. The bark of P. longifolia extracts was extracted using various polar and non-polar solvents and tested for inhibition of alpha-amylase and alpha-glucosidase among which the ethanolic extracts were found to be more potent. The ethanolic extracts of the bark were tested for the in vitro inhibition of alpha-amylase using starch as substrate and alpha-glucosidase using p-nitro phenyl alpha-D-gluco pyranoside as substrate to establish its in vitro antidiabetic effect. The mechanism of inhibition was determined by Dixon plot and Cornish-Bowden plot. The cytotoxic effect of the extract was tested on L6 and Vero cell-lines. The extract was partially purified by TLC. The individual effect of the ethanolic extract, TLC fractions and its combinatorial effect with insulin and glibenclamide on glucose uptake by rat hemi-diaphragm were studied.Results revealed that the ethanolic extracts of Polyalthia longifolia bark exhibited competitive inhibition of alpha-amylase and alpha-glucosidase. The extracts were also found not to be cytotoxic at the highest dose of 1 mg/mL. Glucose uptake study revealed that the extract alone and when combined with insulin, decreased the glucose uptake when compared to insulin control, however the purified TLC fractions exhibited significantly higher (p<0.05) glucose uptake by the rat hemi-diaphragm when compared to insulin. The study shows various possible mechanism of in vitro antidiabetic effect of the P. longifolia bark. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=alpha-amylase" title="alpha-amylase">alpha-amylase</a>, <a href="https://publications.waset.org/abstracts/search?q=alpha-glucosidase" title=" alpha-glucosidase"> alpha-glucosidase</a>, <a href="https://publications.waset.org/abstracts/search?q=dixon" title=" dixon"> dixon</a>, <a href="https://publications.waset.org/abstracts/search?q=cornish-bowden" title=" cornish-bowden"> cornish-bowden</a>, <a href="https://publications.waset.org/abstracts/search?q=L6" title=" L6 "> L6 </a>, <a href="https://publications.waset.org/abstracts/search?q=Vero%20cell-lines" title=" Vero cell-lines"> Vero cell-lines</a>, <a href="https://publications.waset.org/abstracts/search?q=glucose%20uptake" title=" glucose uptake"> glucose uptake</a>, <a href="https://publications.waset.org/abstracts/search?q=polyalthia%20longifolia%20bark" title=" polyalthia longifolia bark"> polyalthia longifolia bark</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract" title=" ethanolic extract"> ethanolic extract</a>, <a href="https://publications.waset.org/abstracts/search?q=TLC%20fractions" title=" TLC fractions"> TLC fractions</a> </p> <a href="https://publications.waset.org/abstracts/34899/mechanism-of-in-vitro-inhibition-of-alpha-amylase-alpha-glucosidase-by-ethanolic-extracts-of-polyalthia-longifolia-its-in-vitro-cytotoxicity-on-l6-vero-cell-lines-and-influence-of-glucose-uptake-by-rat-hemi-diaphragm" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/34899.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">469</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2107</span> Phytochemial Screening, Anti-Microbial, and Minerals Determination of Leptadenia Hastata</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=I.%20L.%20Ibrahim">I. L. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Mann"> A. Mann</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20A.%20Adam"> B. A. Adam </a> </p> <p class="card-text"><strong>Abstract:</strong></p> This project involved screening for antibacterial activity, phytochemical and mineral properties of Leptadenia hastata by flame photometry. The result of phytochemical screening reveals that the presence of flavonoids, tannins, saponins, alkaloids, steroidal, and anthraquinones while the cardiac glycoside was absent. This justifies the plant been used as anti-bleeding and anti-inflammatory agents. The result of flame photometry revealed that 1.85 % (Na), 0.65% (K) and 1.85 % (Ca) which indicates the safe nature of the plant extract as such could be used to lower high blood pressure. The antibacterial properties of both the aqueous and ethanolic extract were studied against some bacteria, Escherichia coli, Bacillus Cercus, Pseudomonas aeruginas, and Enterobacter aerogegens, by disc diffusion method and the result reveals that there are very good activities against the organism while the ethanolic extract at concentration 1.0 – 1.2 mg/ml. the ethanolic extract showed in considerable zone inhibition against bacteria’s; Escherichia coli, Bacillus Cercus, pseudomonas aeruginosa andklebsellapnemuoniae. Minimum inhibitory concentration (MIC) and minimum Bacterial concentration (MBC) were conducted with fairly good significant effect of inhibition on the organism, therefore, plant extract could be a potential source of antibacterial agent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20activity" title="antibacterial activity">antibacterial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=Leptadenia%20hastata" title=" Leptadenia hastata"> Leptadenia hastata</a>, <a href="https://publications.waset.org/abstracts/search?q=infectious%20diseases" title=" infectious diseases"> infectious diseases</a>, <a href="https://publications.waset.org/abstracts/search?q=phytochemical%20screening" title=" phytochemical screening "> phytochemical screening </a> </p> <a href="https://publications.waset.org/abstracts/25213/phytochemial-screening-anti-microbial-and-minerals-determination-of-leptadenia-hastata" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25213.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">588</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2106</span> Assessment of Bio-Control Quality of Ethanolic Extracts of Some Tropical Plants on Fruit Rot Pathogens of Pineapple Fruits in Ado Ekiti</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20Y.%20Ijato">J. Y. Ijato</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Adewumi"> A. Adewumi</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20O%20Yakubu"> H. O Yakubu</a>, <a href="https://publications.waset.org/abstracts/search?q=O.%20O.%20Olajide"> O. O. Olajide</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20O.%20Ojo"> B. O. Ojo</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20A.%20Adanikin"> B. A. Adanikin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Post-harvest fruit rot pathogens are one of the major factors that are responsible for food security challenges in developing countries like Nigeria. These pathogens also cause fruit food poisoning. Biocidal effects of ethanolic extracts of Khaya grandifoliola, Hyptis suaveolens, Zingiber officinale, Calophyllum inophyllum, Datura stramonium on the mycelia growth of fungal rot pathogens of pineapple fruit was investigated, the ethanolic extracts of these test plants exhibited high significant inhibitory effects on the rot pathogens, the highest ethanolic extract inhibition of Zingiber officinale was on Aspergillus flavus (38.40%) at 1.0g/ml while the least inhibitory effect was on Aspergillus fumigatus (23.10%) at 1.0g/ml, the highest ethanol extract inhibition of Datura stramonium was on Aspergillus tubingensis (24.00%) at 1.0g/ml while the least inhibitory effect was 10.00% on Colletotrichum fruticola at 1.0g/ml, the highest ethanol extract inhibition of Calophyllum inophyllum was on Trichoderma harzianum (18.50%) at 1.0g/ml while the least inhibitory effect was on Aspergillus flavus (15.00%) at 1.0g/ml, the highest ethanol extract inhibition of Hyptis suaveolens was on Aspergillus fumigatus (35.00%) at 1.0g/ml while the least inhibitory effect was on Aspergillus niger (20.00%) at 1.0g/ml, the highest ethanol extract inhibition of Khaya grandifoliola was on Aspergillus flavus (35.00%) at 1.00g/ml while the least inhibitory effect was on Aspergillus fumigates (22.00%) at 1.0g/ml, the antifungal capacity of these test plant extracts on rot causing fungi on pineapple fruit reveals the possibility of their use by farmers and fruit traders as alternative to chemical fungicide that portends great threat to human and environmental health. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fruit%20rot" title="fruit rot">fruit rot</a>, <a href="https://publications.waset.org/abstracts/search?q=pathogens" title=" pathogens"> pathogens</a>, <a href="https://publications.waset.org/abstracts/search?q=plant%20extracts" title=" plant extracts"> plant extracts</a>, <a href="https://publications.waset.org/abstracts/search?q=pineapple" title=" pineapple"> pineapple</a>, <a href="https://publications.waset.org/abstracts/search?q=food%20poisoning" title=" food poisoning"> food poisoning</a> </p> <a href="https://publications.waset.org/abstracts/154335/assessment-of-bio-control-quality-of-ethanolic-extracts-of-some-tropical-plants-on-fruit-rot-pathogens-of-pineapple-fruits-in-ado-ekiti" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/154335.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">110</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2105</span> The Hypoglycaemic and Antioxidant Effects of Ethanolic Extract of Curcuma Longa Rhizomes Alone and with Two Pepper Adjuvants in Alloxan-Induced Diabetic Rats </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20O.%20Ezekwesili-Ofili">J. O. Ezekwesili-Ofili</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20I.%20Okorafor"> L. I. Okorafor</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20C.%20Nsofor"> S. C. Nsofor </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diabetes mellitus is a carbohydrate metabolism disorder due to an absolute or relative deficiency of insulin secretion, action or both. Many known hypoglycaemic drugs are known to produce serious side effects. However, the search for safer and more effective agents has shifted to plant products, including foods and spices. One of such is the rhizome of Curcuma longa or turmeric, which is a spice with high medicinal value. A drawback in the use of C. longa is the poor bioavailability of curcumin, the active ingredient. It has been reported that piperine, an alkaloid present in peppers increases the bioavailability of curcumin. This work therefore investigated the hypoglycaemic and antioxidant effects of ethanolic extract of C. longa rhizomes, alone and with two pepper adjuvants in alloxan-induced diabetic rats. A total of 48 rats were divided into 6 groups of 8 rats each. Groups A–E were induced with diabetes using 150mg/kg body weight of alloxan monohydrate, while group F was normoglycaemic: Group A: Diabetic; fed with 400 mg/g body weight of turmeric extract; group B: Diabetic, fed with 400 mg/kg b. w. and 200mg/kg b. w of ethanolic extract of seeds of Piper guinensee; group C: Diabetic, fed with 400 mg/kg b. w. and 200 mg /kg b. w. of ethanolic extract of seeds of Capsicum annum var cameroun, group D: Diabetic, treated with standard drug, glibenclamide (0.3mg/kg body weight), group E: Diabetic; no treatment i.e. Positive control and group F: non diabetic, no treatment i.e. Negative control. Blood glucose levels were monitored for 14 days using a glucometer. The levels of the antioxidant enzymes; glutathione peroxidase, catalase and superoxide dismutase were also assayed in serum. The ethanolic extracts of C. longa rhizomes at the dose given (400 mg/kg b. w) significantly reduced the blood glucose levels of the diabetic rats (p<0.05) comparable to the standard drug. Co administration of extract of the peppers did not significantly increase the efficiency of the extract, although C. annum var cameroun showed greater effect, though not significantly. The antioxidant effect of the extract was significant in diabetic rats. The use of piperine-containing peppers enhanced the antioxidant effect. Phytochemical analyses of the ethanolic extract of C. longa showed the presence of alkaloids, flavonoids, steroids, saponins, tannins, glycosides, and terpenoids. These results suggest that the ethanolic extract of C. longa had antidiabetic with antioxidant effects and could thus be of benefit in the treatment and management of diabetes as well as ameliorate pro-oxidant effects that may lead to diabetic complications. However, while the addition of piperine did not affect the antidiabetic effect of C. longa, the antioxidant effect was greatly enhanced. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title="antioxidant">antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=Curcuma%20longa%20rhizome" title=" Curcuma longa rhizome"> Curcuma longa rhizome</a>, <a href="https://publications.waset.org/abstracts/search?q=hypoglycaemic" title=" hypoglycaemic"> hypoglycaemic</a>, <a href="https://publications.waset.org/abstracts/search?q=pepper%20adjuvants" title=" pepper adjuvants"> pepper adjuvants</a>, <a href="https://publications.waset.org/abstracts/search?q=piperine" title=" piperine"> piperine</a> </p> <a href="https://publications.waset.org/abstracts/45413/the-hypoglycaemic-and-antioxidant-effects-of-ethanolic-extract-of-curcuma-longa-rhizomes-alone-and-with-two-pepper-adjuvants-in-alloxan-induced-diabetic-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/45413.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">236</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2104</span> Effects of Ethanolic Purslane Shoot and Seed Extracts on Doxorubicin-Induced Hepatotoxicity in Albino Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Osama%20M.%20Ahmed">Osama M. Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Walaa%20G.%20Hozayen"> Walaa G. Hozayen</a>, <a href="https://publications.waset.org/abstracts/search?q=Haidy%20Tamer%20Abo%20Sree"> Haidy Tamer Abo Sree</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Doxorubicin (DOX), an anthracycline antibiotic is a broad-spectrum antineoplastic agent, which is commonly used in the treatment of uterine, ovarian, breast and lung cancers, Hodgkin's disease and soft tissue sarcomas as well as in several other cancer types. The effect of doxorubicin (4 mg/kg b.w.week) without or with oral administration of ethanolic purslane (Portulaca oleracea) shoot (leaves and stems) extract (50 mg/kg b.w. day) or ethanolic purslane seeds extract (50 mg/kg b.w.day) co-treatments for 6 weeks was evaluated in adult male rats. Serum ALT, AST, ALP, GGT, total bilirubin, total protein, and albumin levels were assayed. Lipid peroxidation (indexed by MDA) and antioxidants like hepatic glutathine, glutathione transferase, peroxidase, SOD, and CAT were assessed. There was an increase in serum levels of ALT, AST, ALP, GGT and total bilirubin. In addition, hepatic glutathine, glutathione transferase, peroxidase, SOD, and CAT activities were decreased while lipid peroxidation in the liver was increased. Co-administration of ethanolic purslane and seed extracts successfully improved the adverse changes in the liver functions with an increase in antioxidants activities and reduction of lipid peroxidation. In conclusion, it can be supposed that dietary purslane extract supplementation may provide a cushion for a prolonged therapeutic option against DOX hepatopathy without harmful side effects. However, further clinical studies are required to assess the safety and efficacy of these extract in human beings. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=doxorubicin" title="doxorubicin">doxorubicin</a>, <a href="https://publications.waset.org/abstracts/search?q=purslane" title=" purslane"> purslane</a>, <a href="https://publications.waset.org/abstracts/search?q=hepatotoxicity" title=" hepatotoxicity"> hepatotoxicity</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidants" title=" antioxidants"> antioxidants</a> </p> <a href="https://publications.waset.org/abstracts/30878/effects-of-ethanolic-purslane-shoot-and-seed-extracts-on-doxorubicin-induced-hepatotoxicity-in-albino-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30878.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">521</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2103</span> Antioxidant and Anticancer Activities of Ethanolic Extract from Monascus purpureus</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Pourshirazi">M. Pourshirazi</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Esmaelifar"> M. Esmaelifar</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Aliahmadi"> A. Aliahmadi</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Yazdian"> F. Yazdian</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20S.%20Hatamian%20Zarami"> A. S. Hatamian Zarami</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20J.%20Ashrafi"> S. J. Ashrafi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Medicinal fungi are the new potential source of drugs to improve the treatment of diseases with association to oxidative agents such as cancers. Monascus purpureus contains functional components potentially effective in improving human health. In the present work, ethanolic extract of Monascus purpureus (EEM) was evaluated for health improving potential mainly focusing on antioxidant and anticancer activities. Ferric ion reducing power (FRAP), scavenging of DPPH radicals and determining viability of breast carcinoma MCF-7 and cervical carcinoma HeLa cells with MTT assay were evaluated. Our data showed a significant antioxidant activity of EEM with 142.45 µg/ml inhibition concentration of 50% DPPH radicals and 2112.33 µg eq.Fe2+/mg extract of FRAP assay. These results might be caused by antioxidant components such as pigments and phenolic compounds. Further, the results demonstrated that EEM caused significant reduction in the viability of MCF-7 with IC50 of 7 µg/ml but not have good effect against viability of HeLa cells. Accordingly, Monascus purpureus is presented as a strong potential of breast cancer treatment. In further study, the mechanistic studies are needed to determine the mechanisms of anticancer activity of EEM. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Monascus%20purpureus" title="Monascus purpureus">Monascus purpureus</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant" title=" antioxidant"> antioxidant</a>, <a href="https://publications.waset.org/abstracts/search?q=cancer" title=" cancer"> cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract" title=" ethanolic extract"> ethanolic extract</a> </p> <a href="https://publications.waset.org/abstracts/9514/antioxidant-and-anticancer-activities-of-ethanolic-extract-from-monascus-purpureus" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/9514.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">415</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2102</span> In vitro Larvicidal Activity of Varying Concentrations of Madre De Cacao (Gliricidia sepium) Concentrated Crude Ethanolic Extract against Larvae of Horn Fly (Haematobia irritans) </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Antonio%20B.Tangayan%20Jr.">Antonio B.Tangayan Jr.</a>, <a href="https://publications.waset.org/abstracts/search?q=Hershey%20P.%20Mondejar"> Hershey P. Mondejar</a>, <a href="https://publications.waset.org/abstracts/search?q=Pet%20Roey%20Pascual"> Pet Roey Pascual</a>, <a href="https://publications.waset.org/abstracts/search?q=Zeam%20Voltaire%20E.%20Amper"> Zeam Voltaire E. Amper</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A study on in vitro larvicidal acitivity of different levels of Madre de Cacao (Gliricidia sepium) concentrated crude ethanolic extract (CCEE) against horn fly larvae (Haematobia irritans) was conducted. The air-dried leaves of Gliricidia sepium were infused in a 1:3 ratio (w/v) using ethanol as solvent and concentrated in a rotary evaporator (60°C). A total of 120 larvae of Haematobia irritans were exposed in various concentration: 200, 400, 800 and 1000 ppm. Based on the result after 5 hours of exposure, CCE G. sepium extract at 200 ppm showed less effect with 30% mortality compared to 400 ppm, 800 ppm and 1000 ppm with 70%, 83%, and 100% mortality, respectively. Findings also revealed that CCE of G. sepium extract at 1000 ppm, 800 ppm, and commercial larvicide were comparable in causing mortality of H. irritans larvae from the first hour up to the fifth hours of exposure. However, on the fifth hour, 400 ppm was also found to be effective. This suggests that the higher the concentration of CCE G. sepium extract and the longer the time of exposure, the higher is the percentage mortality of the larvae. Thus, CCE G. sepium extract can be used as an alternative for commercial larvicide. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=horn%20fly" title="horn fly">horn fly</a>, <a href="https://publications.waset.org/abstracts/search?q=in%20vitro" title=" in vitro"> in vitro</a>, <a href="https://publications.waset.org/abstracts/search?q=larvicidal" title=" larvicidal"> larvicidal</a>, <a href="https://publications.waset.org/abstracts/search?q=Madre%20de%20Cacao" title=" Madre de Cacao"> Madre de Cacao</a> </p> <a href="https://publications.waset.org/abstracts/57364/in-vitro-larvicidal-activity-of-varying-concentrations-of-madre-de-cacao-gliricidia-sepium-concentrated-crude-ethanolic-extract-against-larvae-of-horn-fly-haematobia-irritans" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/57364.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">284</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2101</span> Cytotoxicity of Flavonoid Compounds from Smilax corbularia Kunth Against Cholangiocarcinoma Cell Line</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pakakrong%20Thongdeeying">Pakakrong Thongdeeying</a>, <a href="https://publications.waset.org/abstracts/search?q=Srisopa%20Ruangnoo"> Srisopa Ruangnoo</a>, <a href="https://publications.waset.org/abstracts/search?q=Arunporn%20Itharat"> Arunporn Itharat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The rhizomes of Smilax corbularia Kunth have long been used as common ingredients in anticancer preparations. Thus, the objective of this study is to investigate cytotoxicity of S. corbularia and its ingredients against cholangiocarcinoma cell line (KKU-M156) by SRB assay. Ethanolic and water extracts of S. corbularia rhizomes were obtained using the procedures followed by Thai traditional doctors. Bioassay guided isolation was used to isolate cytotoxic compounds. The results revealed that the ethanolic extract of S. corbularia exhibited activity against KKU-M156 cell line with an IC50 value of 84.53±1.62 µg/ml, but the water extract showed no cytotoxic activity. Three flavonoid compounds [astilbin (1), engeletin (2), and quercetin (3)] were isolated from the ethanolic extract. Compound 3 exhibited the strongest activity against KKU-M156 cell line (IC50 = 8.14 ± 1.15 µg/ml), but 1 and 2 showed no cytotoxic activity (IC50 > 100 µg/ml). In conclusion, quercetin showed the highest efficacy against cholangiocarcinoma. These results support the traditional use of this plant by Thai traditional doctors for cancer treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cholangiocarcinoma" title="cholangiocarcinoma">cholangiocarcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=cytotoxicity" title=" cytotoxicity"> cytotoxicity</a>, <a href="https://publications.waset.org/abstracts/search?q=flavonoid" title=" flavonoid"> flavonoid</a>, <a href="https://publications.waset.org/abstracts/search?q=Smilax%20corbularia" title=" Smilax corbularia "> Smilax corbularia </a> </p> <a href="https://publications.waset.org/abstracts/25235/cytotoxicity-of-flavonoid-compounds-from-smilax-corbularia-kunth-against-cholangiocarcinoma-cell-line" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/25235.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">381</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2100</span> Role of Inflammatory Markers in Arthritic Rats Treated with Ethanolic Bark Extract of Albizia procera</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Sangeetha">M. Sangeetha</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Chamundeeswari"> D. Chamundeeswari</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Saravanababu"> C. Saravanababu</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Rose"> C. Rose</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Gopal"> V. Gopal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> <p class="Abstract" style="text-indent:10.2pt"><span lang="EN-US">Rheumatoid arthritis (RA) is a chronic, progressive, systemic inflammatory disorder affecting the synovial joints and typically producing symmetrical arthritis that leads to joint destruction, which is responsible for the deformity and disability. Despite improvements in the treatment of RA over the past decade, there still is a need for new therapeutic agents that are efficacious, less expensive, and free of severe adverse reactions. The present study aimed to investigate role of inflammatory markers in arthritic rats treated with ethanolic bark extract of <i>Albizia procera</i>. The protective effect of ethanolic bark extract of <i>Albizia procera </i>against complete Freund’s adjuvant (CFA) induced arthritis in rats. Arthritis was induced by an intradermal injection of 0.1 ml FCA in the foot pad of left hind limb of rats. ETBE (100 and 200 mg/kg b.wt./p.o) and the reference drug diclofenac (25 mg/kg b.wt./p.o) were administered to arthritic rats. Paw volume was measured for all the animals before inducing arthritis and thereafter once in seven days by using plethysmometer for 42 days. Gene expression of inflammatory markers such as IL-1β and IL-10 were investigated in paw tissues. Up regulation of IL-1β and Down regulation IL-10 were observed in CFA injected rats when compared to normal rats. ETBE attenuated these alterations dose dependently when compared to the vehicle treated rats. These results provide insights into the mechanism of anti-arthritic activity, and unravel potential therapeutic use of <i>Albizia procera </i>in arthritis.<o:p> </o:p></span> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CFA-Complete%20Freund%E2%80%99s%20adjuvant" title="CFA-Complete Freund’s adjuvant">CFA-Complete Freund’s adjuvant</a>, <a href="https://publications.waset.org/abstracts/search?q=ETBE%20%E2%80%93%20ethanolic%20bark%20extract" title=" ETBE – ethanolic bark extract"> ETBE – ethanolic bark extract</a>, <a href="https://publications.waset.org/abstracts/search?q=IL-%20interleukins" title=" IL- interleukins"> IL- interleukins</a>, <a href="https://publications.waset.org/abstracts/search?q=RA-rheumatoid%20arthritis" title=" RA-rheumatoid arthritis"> RA-rheumatoid arthritis</a> </p> <a href="https://publications.waset.org/abstracts/52352/role-of-inflammatory-markers-in-arthritic-rats-treated-with-ethanolic-bark-extract-of-albizia-procera" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52352.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">285</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2099</span> Physiochemical and Antibacterial Assessment of Iranian Propolis Gathering in Qazvin Province </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nematollah%20Gheibi">Nematollah Gheibi</a>, <a href="https://publications.waset.org/abstracts/search?q=Nader%20Divan%20Khosroshahi"> Nader Divan Khosroshahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahdi%20Mohammadi%20Ghanbarlou"> Mahdi Mohammadi Ghanbarlou </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Nowadays, the phenomenon of bacterial resistance is one of the most important challenge of the health community in the world. Propolis is most important production of bee colonies that collected from of various plants. So far, a lot of investigations carried out about its antibacterial effects. Material and methods: Thirty gram of propolis prepared as ethanolic extract and after different process of purification, 7.5 gr of its pure form were obtained. Propolis compounds identification was performed by TLC and VLC methods. The HPLC spectrum obtaining from propolis ethanolic extract was compared with some purified standard phenolic and flavonoid substances. Antibacterial effects of ethanol extract of purified propolis were evaluated on two strains of Staphylococcus aureus and Pseudomonas aeruginosa and their MIC was determined by the microdillution assay. Results: Ethanolic propolis extraction analyzed by TLC were resulted to confirm several phenolic and flavonoid compounds in this extract and some of the confirmed by HPLC technique. Minimum inhibitory concentration (MIC) for standard Staphylococcus aureus (ATCC25923) and Pseudomonas aeruginosa (ATCC27853) strains were obtained 2.5 mg/ml and 50 mg/ml respectively. Conclusion: Bee Propolis is a mix organic compound that has a lot of beneficial effects such as anti-bacterial that emphasized in this investigation. It is proposed as a rich source of natural phenolic and flavonoids compounds in designing of new biological resources for hygienic and medical applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=propolis" title="propolis">propolis</a>, <a href="https://publications.waset.org/abstracts/search?q=Staphylococcus%20aureus" title=" Staphylococcus aureus"> Staphylococcus aureus</a>, <a href="https://publications.waset.org/abstracts/search?q=Pseudomonas%20aeruginosa" title=" Pseudomonas aeruginosa"> Pseudomonas aeruginosa</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial" title=" antibacterial"> antibacterial</a> </p> <a href="https://publications.waset.org/abstracts/12023/physiochemical-and-antibacterial-assessment-of-iranian-propolis-gathering-in-qazvin-province" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/12023.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">305</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2098</span> The Effect of Different Concentrations of Extracting Solvent on the Polyphenolic Content and Antioxidant Activity of Gynura procumbens Leaves</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kam%20Wen%20Hang">Kam Wen Hang</a>, <a href="https://publications.waset.org/abstracts/search?q=Tan%20Kee%20Teng"> Tan Kee Teng</a>, <a href="https://publications.waset.org/abstracts/search?q=Huang%20Poh%20Ching"> Huang Poh Ching</a>, <a href="https://publications.waset.org/abstracts/search?q=Chia%20Kai%20Xiang"> Chia Kai Xiang</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20V.%20Annegowda"> H. V. Annegowda</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20S.%20Naveen%20Kumar"> H. S. Naveen Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Gynura procumbens (G. procumbens) leaves, commonly known as ‘sambung nyawa’ in Malaysia is a well-known medicinal plant commonly used as folk medicines in controlling blood glucose, cholesterol level as well as treating cancer. These medicinal properties were believed to be related to the polyphenolic content present in G. procumbens extract, therefore optimization of its extraction process is vital to obtain highest possible antioxidant activities. The current study was conducted to investigate the effect of different concentrations of extracting solvent (ethanol) on the amount of polyphenolic content and antioxidant activities of G. procumbens leaf extract. The concentrations of ethanol used were 30-70%, with the temperature and time kept constant at 50°C and 30 minutes, respectively using ultrasound-assisted extraction. The polyphenolic content of these extracts were quantified by Folin-Ciocalteu colorimetric method and results were expressed as milligram gallic acid equivalent (mg GAE)/g. Phosphomolybdenum method and 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assays were used to investigate the antioxidant properties of the extract and the results were expressed as milligram ascorbic acid equivalent (mg AAE)/g and effective concentration (EC50) respectively. Among the three different (30%, 50% and 70%) concentrations of ethanol studied, the 50% ethanolic extract showed total phenolic content of 31.565 ± 0.344 mg GAE/g and total antioxidant activity of 78.839 ± 0.199 mg AAE/g while 30% ethanolic extract showed 29.214 ± 0.645 mg GAE/g and 70.701 ± 1.394 mg AAE/g, respectively. With respect to DPPH radical scavenging assay, 50% ethanolic extract had exhibited slightly lower EC50 (314.3 ± 4.0 μg/ml) values compared to 30% ethanol extract (340.4 ± 5.3 μg/ml). Out of all the tested extracts, 70% ethanolic extract exhibited significantly (p< 0.05) highest total phenolic content (38.000 ± 1.009 mg GAE/g), total antioxidant capacity (95.874 ± 2.422 mg AAE/g) and demonstrated the lowest EC50 in DPPH assay (244.2 ± 5.9 μg/ml). An excellent correlations were drawn between total phenolic content, total antioxidant capacity and DPPH radical scavenging activity (R2 = 0.949 and R2 = 0.978, respectively). It was concluded from this study that, 70% ethanol should be used as the optimal polarity solvent to obtain G. procumbens leaf extract with maximum polyphenolic content with antioxidant properties. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title="antioxidant activity">antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=DPPH%20assay" title=" DPPH assay"> DPPH assay</a>, <a href="https://publications.waset.org/abstracts/search?q=Gynura%20procumbens" title=" Gynura procumbens"> Gynura procumbens</a>, <a href="https://publications.waset.org/abstracts/search?q=phenolic%20compounds" title=" phenolic compounds"> phenolic compounds</a> </p> <a href="https://publications.waset.org/abstracts/42004/the-effect-of-different-concentrations-of-extracting-solvent-on-the-polyphenolic-content-and-antioxidant-activity-of-gynura-procumbens-leaves" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/42004.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">411</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2097</span> Effects of Purslane Shoot and Seed Ethanolic Extracts on Doxorubicin-Induced Testicular Toxicity in Albino Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Walaa%20G.%20Hozayen">Walaa G. Hozayen</a>, <a href="https://publications.waset.org/abstracts/search?q=Osama%20M.%20Ahmed"> Osama M. Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Haidy%20T.%20Abo%20Sree"> Haidy T. Abo Sree</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The clinical usefulness of anthracycline antineoplastic antibiotic, doxorubicin (DOX) is restricted since it has several acute and chronic side effects. The effect of doxorubicin (4 mg/kg b.w/week) without or with oral administration of purslane (Portulaca oleracea) shoot ethanolic extract (50mg/kg b.w./day) and purslane seed ethanolic extract (50mg/kg b.w./day) co-treatments for 6 weeks was evaluated in adult male rats. Serum testosterone luteinizing hormone (LH), follicle stimulating hormone (FSH) level were assayed. Testis lipid peroxidation (indexed by MDA) and antioxidants like glutathione (GSH), glutathione-S-transferase (GST), peroxidase (POX), superoxide dismutase (SOD), catalase (CAT) levels in testis were assessed. The data revealed a significant decrease in serum levels concentration of testosterone, LH and FSH levels in doxorubicin-injected rats. In addition, testis glutathione, glutathione transferase, peroxidase, SOD and CAT levels were decreased while lipid peroxidation concentration in the testis was increased as a result of doxorubicin injection. Co-administration of ethanolic purslane and seed extracts potentially improved the adverse changes in serum testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH) levels with an increase in testis antioxidants levels and reduction in lipid peroxidation. In conclusion, it can be suggested that dietary purslane extract supplementation may provide a cushion for a prolonged therapeutic option against DOX testicular toxicity without harmful side effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=doxorubicin" title="doxorubicin">doxorubicin</a>, <a href="https://publications.waset.org/abstracts/search?q=purslane" title=" purslane"> purslane</a>, <a href="https://publications.waset.org/abstracts/search?q=testis%20function" title=" testis function"> testis function</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidants" title=" antioxidants"> antioxidants</a> </p> <a href="https://publications.waset.org/abstracts/10480/effects-of-purslane-shoot-and-seed-ethanolic-extracts-on-doxorubicin-induced-testicular-toxicity-in-albino-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/10480.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">335</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2096</span> The Antidiabetic Properties of Indonesian Swietenia mahagoni in Alloxan-Induced Diabetic Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=T.%20Wresdiyati">T. Wresdiyati</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Sa%E2%80%99diah"> S. Sa’diah</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Winarto"> A. Winarto</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diabetes mellitus (DM) is a metabolic disease that can be indicated by the high level of blood glucose. The objective of this study was to observe the antidiabetic properties of ethanolic extract of Indonesian <em>Swietenia mahagoni </em>Jacq. seed on the profile of pancreatic superoxide dismutase and β-cells in the alloxan- experimental diabetic rats. The <em>Swietenia mahagoni </em>seed was obtained from Leuwiliang-Bogor, Indonesia. Extraction of <em>Swietenia mahagoni </em>was done by using ethanol with maceration methods. A total of 25 male <em>Sprague dawley </em>rats were divided into five groups; (a) negative control group, (b) positive control group (DM), (c) DM group that was treated with <em>Swietenia mahagoni</em> seed extract, (d) DM group that was treated with acarbose, and (e) non-DM group that was treated with <em>Swietenia mahagoni </em>seed extract. The DM groups were induced by alloxan (110 mg/kgBW). The extract was orally administrated to diabetic rats 500 mg/kg/BW/day for 28 days. The extract showed hypoglycemic effect, increased body weight, increased the content of superoxide dismutase in the pancreatic tissue, and delayed the rate of β-cells damage of experimental diabetic rats. These results suggested that the ethanolic extract of Indonesian <em>Swietenia mahagoni </em>Jacq. seed could be proposed as a potential anti-diabetic agent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=beta%20cells" title="beta cells">beta cells</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes" title=" diabetes"> diabetes</a>, <a href="https://publications.waset.org/abstracts/search?q=hypoglycemic" title=" hypoglycemic"> hypoglycemic</a>, <a href="https://publications.waset.org/abstracts/search?q=rat" title=" rat"> rat</a>, <a href="https://publications.waset.org/abstracts/search?q=Swietenia%20mahagoni" title=" Swietenia mahagoni"> Swietenia mahagoni</a> </p> <a href="https://publications.waset.org/abstracts/50793/the-antidiabetic-properties-of-indonesian-swietenia-mahagoni-in-alloxan-induced-diabetic-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/50793.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">294</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2095</span> Arisarum Vulgare: Bridging Tradition and Science through Phytochemical Characterization and Exploring Therapeutic Potential via in vitro and in vivo Biological Activities</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Boudjelal%20Amel">Boudjelal Amel</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Arisarum vulgare, a member of the Araceae family, is an herbaceous perennial widely distributed in the Mediterranean region. A. vulgare is recognized for its medicinal properties and holds significant traditional importance in Algeria for the treatment of various human ailments, including pain, infections, inflammation, digestive disorders, skin problems, eczema, cancer, wounds, burns and gynecological diseases. Despite its extensive traditional use, scientific exploration of A. vulgare remains limited. The study aims to investigate for the first time the therapeutic potential of A. vulgare ethanolic extract obtained by ultrasound-assisted extraction. The chemical composition of the extract was determined by LC-MS/MS analysis. For in vitro phytopharmacological evaluation, several assays, including DPPH, ABTS, FRAP and reducing power, were employed to evaluate the antioxidant activity. The antibacterial activity was assessed againt Escherichia coli, Salmonella typhimurium, Staphylococus aureus, Enterococcus feacium by disk diffusion and microdilution methods. The possible inhibitory activity of ethanolic extract was analyzed against the cholinesterases enzymes (AChE and BChE). The DNA protection activity of A. vulgare ethanolic extract was estimated using the agarose gel electrophoresis method. The capacities of the extract to protect plasmid DNA (pBR322) from the oxidizing effects of H2O2 and UV treatment were evaluated by their DNA-breaking forms. The in vivo wound healing potential of a traditional ointment containing 5% of A. vulgare ethanolic extract was also investigated. The LC-MS/MS profiling of the extract revealed the presence of various bioactive compounds, including naringenin, chlorogenic, vanillic, cafeic, coumaric acids, trans-cinnamic and trans ferrulic acids. The plant extract presented considerable antioxidant potential, being the most active for Reducing power (0,07326±0.001 mg/ml) and DPPH (0.14±0.004 mg/ml). The extract showed the highest inhibition zone diameter against Enterococcus feacium (36±0.1 mm). The ethanolic extract of A. vulgare suppressed the growth of Staphylococus aureus, Escherichia coli and Salmonella typhimurium according to the MIC values. The extract of the plant significantly inhibited both AChE and BChE enzymes. DNA protection activity of the A. vulgare extract was determined as 90.41% for form I and 51.92% for form II. The in vivo experiments showed that 5% ethanolic extract ointment accelerated the wound healing process. The topical application of the traditional formulation enhanced wound closure (95,36±0,6 %) and improved histological parameters in the treated group compared to the control groups. The promising biological properties of Arisarum vulgare revealed that the plant could be appraised as a potential origin of bioactive molecules having multifunctional medicinal uses. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=arisarum%20vulgare" title="arisarum vulgare">arisarum vulgare</a>, <a href="https://publications.waset.org/abstracts/search?q=LC-MS%2FMS" title=" LC-MS/MS"> LC-MS/MS</a>, <a href="https://publications.waset.org/abstracts/search?q=antioxidant%20activity" title=" antioxidant activity"> antioxidant activity</a>, <a href="https://publications.waset.org/abstracts/search?q=antimicrobial%20activity" title=" antimicrobial activity"> antimicrobial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=cholinesterases%20enzymes%20inhibition" title=" cholinesterases enzymes inhibition"> cholinesterases enzymes inhibition</a>, <a href="https://publications.waset.org/abstracts/search?q=dna-damage%20activity" title=" dna-damage activity"> dna-damage activity</a>, <a href="https://publications.waset.org/abstracts/search?q=in%20vivo%20wound%20healing" title=" in vivo wound healing"> in vivo wound healing</a> </p> <a href="https://publications.waset.org/abstracts/183263/arisarum-vulgare-bridging-tradition-and-science-through-phytochemical-characterization-and-exploring-therapeutic-potential-via-in-vitro-and-in-vivo-biological-activities" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/183263.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">69</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2094</span> Evaluation of the Phenolic Composition of Curcumin from Different Turmeric (Curcuma longa L.) Extracts: A Comprehensive Study Based on Chemical Turmeric Extract, Turmeric Tea and Fresh Turmeric Juice</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Beyza%20Sukran%20Isik">Beyza Sukran Isik</a>, <a href="https://publications.waset.org/abstracts/search?q=Gokce%20Altin"> Gokce Altin</a>, <a href="https://publications.waset.org/abstracts/search?q=Ipek%20Yalcinkaya"> Ipek Yalcinkaya</a>, <a href="https://publications.waset.org/abstracts/search?q=Evren%20Demircan"> Evren Demircan</a>, <a href="https://publications.waset.org/abstracts/search?q=Asli%20Can%20Karaca"> Asli Can Karaca</a>, <a href="https://publications.waset.org/abstracts/search?q=Beraat%20Ozcelik"> Beraat Ozcelik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Turmeric (Curcuma longa L.), is used as a food additive (spice), preservative and coloring agent in Asian countries, including China and South East Asia. It is also considered as a medicinal plant. Traditional Indian medicine evaluates turmeric powder for the treatment of biliary disorders, rheumatism, and sinusitis. It has rich polyphenol content. Turmeric has yellow color mainly because of the presence of three major pigments; curcumin 1,7-bis(4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3,5-dione), demethoxy-curcumin and bis demothoxy-curcumin. These curcuminoids are recognized to have high antioxidant activities. Curcumin is the major constituent of Curcuma species. Method: To prepare turmeric tea, 0.5 gram of turmeric powder was brewed with 250 ml of water at 90°C, 10 minutes. 500 grams of fresh turmeric washed and shelled prior to squeezing. Both turmeric tea and turmeric juice pass through 45 lm filters and stored at -20°C in the dark for further analyses. Curcumin was extracted from 20 grams of turmeric powder by 70 ml ethanol solution (95:5 ethanol/water v/v) in a water bath at 80°C, 6 hours. Extraction was contributed for 2 hours at the end of 6 hours by addition of 30 ml ethanol. Ethanol was removed by rotary evaporator. Remained extract stored at -20°C in the dark. Total phenolic content and phenolic profile were determined by spectrophotometric analysis and ultra-fast liquid chromatography (UFLC), respectively. Results: The total phenolic content of ethanolic extract of turmeric, turmeric juice, and turmeric tea were determined 50.72, 31.76 and 29.68 ppt, respectively. The ethanolic extract of turmeric, turmeric juice, and turmeric tea have been injected into UFLC and analyzed for curcumin contents. The curcumin content in ethanolic extract of turmeric, turmeric juice, and turmeric tea were 4067.4, 156.7 ppm and 1.1 ppm, respectively. Significance: Turmeric is known as a good source of curcumin. According to the results, it can be stated that its tea is not sufficient way for curcumin consumption. Turmeric juice can be preferred to turmeric tea for higher curcumin content. Ethanolic extract of turmeric showed the highest content of turmeric in both spectrophotometric and chromatographic analyses. Nonpolar solvents and carriers which have polar binding sites have to be considered for curcumin consumption due to its nonpolar nature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=phenolic%20compounds" title="phenolic compounds">phenolic compounds</a>, <a href="https://publications.waset.org/abstracts/search?q=spectrophotometry" title=" spectrophotometry"> spectrophotometry</a>, <a href="https://publications.waset.org/abstracts/search?q=turmeric" title=" turmeric"> turmeric</a>, <a href="https://publications.waset.org/abstracts/search?q=UFLC" title=" UFLC"> UFLC</a> </p> <a href="https://publications.waset.org/abstracts/89625/evaluation-of-the-phenolic-composition-of-curcumin-from-different-turmeric-curcuma-longa-l-extracts-a-comprehensive-study-based-on-chemical-turmeric-extract-turmeric-tea-and-fresh-turmeric-juice" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/89625.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">200</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2093</span> Antibacterial Activity of Ethanolic and Aqueous Extracts of Punica Granatum L. Bark </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=H.%20Kadi">H. Kadi</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Moussaoui"> A. Moussaoui</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Medah"> A. Medah</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Benayahia"> N. Benayahia</a>, <a href="https://publications.waset.org/abstracts/search?q=Nahal%20Bouderba"> Nahal Bouderba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> For thousands of years, Punica granatum L. has been used in traditional medicine all over the world and predate the introduction of antibacterial drugs. The aim of the present study was to investigate the antibacterial activity of aqueous and ethanolic extracts of Punica granatum L. bark obtained by decoction and maceration. The different extracts of Punica granatum L. (Lythraceae) bark have been tested for antibacterial activity against Gram-positive bacteria (Staphylococcus aureus, Bacillus stearothermophilus) and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) by disc diffusion method. The ethanolic macerate extract showed the strong in vitro antibacterial activity against Pseudomonas aeruginosa with zone inhibition of 24.4 mm. However, the results tests by disc diffusion method revealed the effectiveness of ethanolic decoctate against Gram-positive bacteria (Staphylococcus aureus and Bacillus stearothermophilus) with diameter zone of inhibition varying with 21.1mm and 23.75 mm respectively. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Punica%20granatum%20L.%20bark" title="Punica granatum L. bark">Punica granatum L. bark</a>, <a href="https://publications.waset.org/abstracts/search?q=antibacterial%20activity" title=" antibacterial activity"> antibacterial activity</a>, <a href="https://publications.waset.org/abstracts/search?q=maceration" title=" maceration"> maceration</a>, <a href="https://publications.waset.org/abstracts/search?q=decoction" title=" decoction "> decoction </a> </p> <a href="https://publications.waset.org/abstracts/21102/antibacterial-activity-of-ethanolic-and-aqueous-extracts-of-punica-granatum-l-bark" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/21102.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">467</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2092</span> Antioxidant Activity of Essential Oils and Ethanolic Extracts of Four Medicinal Plants Alone and in Combination</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fatiha%20Bedjou">Fatiha Bedjou</a>, <a href="https://publications.waset.org/abstracts/search?q=Meriem%20Meddas"> Meriem Meddas</a>, <a href="https://publications.waset.org/abstracts/search?q=Tadjajikt%20Chekkal"> Tadjajikt Chekkal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present work aims to evaluate the antioxidant activity of ethanolic extracts and essential oils of aromatic plants of the Lamiaceae family: Thymus algeriensis and Salvia rosmarinus, and Anacardiaceae: Pistacia lentiscus, Myrtaceae: Eucalyptus polybracetea. The polyphenols were measured using the Folin-Ciocalteu method; the results showed that the essential oils studied as well as the ethanolic extracts are relatively rich in polyphenols. Their antioxidant properties were tested by the synthetic DPPH radical trapping method. The IC50 values were determined according to the graph representing the percentage of inhibition of the DPPH radical by essential oils and by ethanolic extracts, according to our results there is a correlation between the level of polyphenols present in the different essential oils and different ethanolic extracts and their ability to neutralize free radicals. Several combinations were carried out between the essential oils and also between the ethanolic extracts in order to determine the type of interactions existing between the combined substances, the results were represented in the form of isobolograms. Additive and super-additive effects were observed in combinations of essential oils, and super-additive and sub-additive effects were observed for combinations of ethanolic extracts. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=essential%20oils" title="essential oils">essential oils</a>, <a href="https://publications.waset.org/abstracts/search?q=ethanolic%20extracts" title=" ethanolic extracts"> ethanolic extracts</a>, <a href="https://publications.waset.org/abstracts/search?q=DPPH" title=" DPPH"> DPPH</a>, <a href="https://publications.waset.org/abstracts/search?q=combination" title=" combination"> combination</a> </p> <a href="https://publications.waset.org/abstracts/173670/antioxidant-activity-of-essential-oils-and-ethanolic-extracts-of-four-medicinal-plants-alone-and-in-combination" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173670.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">60</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">‹</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract&page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract&page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract&page=4">4</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=ethanolic%20extract&page=5">5</a></li> <li class="page-item"><a class="page-link" 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