CINXE.COM
Custom Antibody Development Services
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id="block-system-main" class="block block-system clearfix"> <div id="node-1098036" class="node node-custom-services clearfix" about="/services/custom-antibody-services" typeof="sioc:Item foaf:Document"> <span property="dc:title" content="Custom Antibody Development Services" class="rdf-meta element-hidden"></span><span property="sioc:num_replies" content="0" datatype="xsd:integer" class="rdf-meta element-hidden"></span> <div class="content"> <div id="srvcs-hero-banner" class="section-row bg-gray"> <div class="row"> <div class="field-items field-hero-50 "> <div class="field-item"><div class="col-xs-12 m-hero-services"> <div class="element col-md-6"> <div class="infobox_text "> <h2>Your Antibody, Our Expertise</h2> <p><p>Generation of new custom antibodies can be a long, frustrating, and potentially expensive process. The probability of success depends on multiple factors including intended use, biological knowledge of the target’s structure and function, appropriate immunogen design, animal model and clonality chosen, immunization strategy, optimized screening methods, efficient purification, and reliable QC.</p> <p>Leverage the experience and expertise of our custom antibody development scientists for your project. Our consultative, stage-gated approach mitigates risk, saves time and increases the probability of your project successfully moving forward.</p> </p> </div> <a href="#8205" title="Request a Quote" class="btn btn-primary">Request a Quote</a> </div> <div class="text-right a-image-hero-services col-md-6 main-container"> <img loading="lazy" src="https://resources.rndsystems.com/images/services/ab/cs-antibody-custom-v4.png" class="" alt="custom antibody services" title="Our custom antibody services allow you to choose from 20,000 primary antibodies, 3,600 target analytes and 25 species."> </div> </div> </div> </div> </div> </div> <div id="comm-immu-plat" class="section-row"> <div class="row"> <div class="col-md-12"> <h2><div class="field field-name-field-common-platform-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Antibody Services</div></div></div></h2> <div class="field-items field-common-platforms "> <div class="row"> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-wrapper"> <div class="element"> <div class="infobox_text "> <h2>Custom Antibody Development</h2> <p><p>Generate custom monoclonal or polyclonal antibodies from scratch. We will work with you from immunogen design through purification and QC to ensure custom antibody specificity and long term supply. Partner with our expert development team.</p> </p> </div> <a href="/services/antibody-production-custom-development-services" title="Antibody Development Capabilities" class="btn btn-senary">Learn About Our Custom Antibody Development Services</a> </div> </div> </div> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-wrapper"> <div class="element"> <div class="infobox_text "> <h2>Custom Recombinant Antibody Production and Custom Antibody Engineering</h2> <p><p>Develop a new custom recombinant antibody or enhance your existing clones. Add engineering services to solve unique technical challenges.</p> </p> </div> <a href="/services/recombinant-antibody-conversion" title="Recombinant Antibody Engineering" class="btn btn-senary">Learn About Our Custom Recombinant Antibody Services</a> </div> </div> </div> </div> <div class="row"> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-wrapper"> <div class="element"> <div class="infobox_text "> <h2>Custom Monoclonal Antibody Panels</h2> <p><p>We have tens of thousands of monoclonal antibodies not listed in our catalog! Expedite your research and create your custom monoclonal antibody panels to find the ideal clone or antibody pair for your desired application.</p> </p> </div> <a href="/services/monoclonal-antibody-panels" title="Monoclonal Antibody Panel Capabilities" class="btn btn-senary">Learn About Our Custom Monoclonal Antibody Panels</a> </div> </div> </div> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-wrapper"> <div class="element"> <div class="infobox_text "> <h2>Custom GMP Antibodies Services</h2> <p><p>Manufacture custom antibodies for drug discovery, diagnostic, and cell <em>ex vivo</em> use. Develop an antibody from scratch, or convert an existing research-grade antibody into a recombinant antibody. Ensure consistent supply of your raw materials through our established scale-up and scale-out manufacturing processes.</p> </p> </div> <a href="/services/gmp-antibody-services" title="Custom GMP Antibodies Services" class="btn btn-senary">Learn About Our GMP Antibody Services</a> </div> </div> </div> </div></div> </div> </div> </div> <div id="srvcs-what-to-exp" class="section-row"> <div class="row section-row"> <div class="col-md-12"> <h2><div class="field field-name-field-what-to-expect-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">What to Expect</div></div></div></h2> <div class="field-items field-what-to-expect "> <div class="row"> <div class="field-item"><div class="col-xs-12 col-sm-6 image-left-wrapper"> <div class="wte-box bg-gray"> <div class="row row-eq-height"> <div class="col-md-2 col-xs-12"> <div class="wte-icon text-center"> <div class="infobox_image left"> <img loading="lazy" src="//resources.rndsystems.com/images/services/ab/icons-speed-fast.svg" class="" alt="High performance antibodies" title="High Performance Products"> </div> </div> </div> <div class="col-md-10 col-xs-12"> <h5>High Performance Products</h5> <p><p>R&D Systems is known for its quality products, lot to lot consistency, and long-term supply. You can expect the same for your customized antibody reagents. We will provide the highly specific, customized antibodies you need to move your project forward!</p> </p> </div> </div> </div> </div> </div> <div class="field-item"><div class="col-xs-12 col-sm-6 image-left-wrapper"> <div class="wte-box bg-gray"> <div class="row row-eq-height"> <div class="col-md-2 col-xs-12"> <div class="wte-icon text-center"> <div class="infobox_image left"> <img loading="lazy" src="//resources.rndsystems.com/images/services/ab/icons-users-plus.svg" class="" alt="Access to scientist who develop antibodies" title="Access To Scientists"> </div> </div> </div> <div class="col-md-10 col-xs-12"> <h5>Access To Scientists</h5> <p><p>Our custom reagents are developed by the same scientists that make the retail products you trust. Utilize their decades of experience from project design to delivery. With full length, active immunogens and optimized protocols tailored to your project, we will ensure your specifications are met.</p> </p> </div> </div> </div> </div> </div> </div> <div class="row"> <div class="field-item"><div class="col-xs-12 col-sm-6 image-left-wrapper"> <div class="wte-box bg-gray"> <div class="row row-eq-height"> <div class="col-md-2 col-xs-12"> <div class="wte-icon text-center"> <div class="infobox_image left"> <img loading="lazy" src="//resources.rndsystems.com/images/services/ab/icons-list3.svg" class="" alt="Customized antibodies " title="Customized Reagents and Testing"> </div> </div> </div> <div class="col-md-10 col-xs-12"> <h5>Customized Reagents and Testing</h5> <p><p>With unique engineering solutions, we can tailor your reagent to meet the requirements of your application. Using our existing protocols, we can provide you the optimal reagent on your timeline.</p> </p> </div> </div> </div> </div> </div> <div class="field-item"><div class="col-xs-12 col-sm-6 image-left-wrapper"> <div class="wte-box bg-gray"> <div class="row row-eq-height"> <div class="col-md-2 col-xs-12"> <div class="wte-icon text-center"> <div class="infobox_image left"> <img loading="lazy" src="//resources.rndsystems.com/images/services/ab/icons-file-preview.svg" class="" alt="Validated antibodies" title="Quality Oversight"> </div> </div> </div> <div class="col-md-10 col-xs-12"> <h5>Quality Oversight</h5> <p><p>All our custom antibody services are governed by established, rigorous quality assurance measures, so you can be confident in the accuracy of the data and the performance of your custom product.</p> </p> </div> </div> </div> </div> </div> </div></div> </div> </div> </div> <div id="about-us" class="row"> <div class="col-xs-12 col-sm-6"><div> <div class="field-items"> <div class="field-item display-image-field even"><div class="col-xs-12"> <h2>About Us</h2> <p><p>Bio-Techne has more than 3 decades of antibody development experience and continues to provide customers with the most consistent and highly validated antibodies on the market today. Our team of antibody development scientists are committed to applying our expertise to optimize and tailor our antibody development protocols to give customers the best antibodies available.</p> <p>We are dedicated to ensuring our custom antibody solution fits the customer’s needs by utilizing cutting edge protocols and incorporating recombinant antibody technology and antibody engineering. Our custom antibody projects are always our number one priority. We devote a project manager and a team of development scientists to your project. Together, we successfully complete your custom antibody project to your specifications with the highest quality standards.</p> <p><strong>Julia Hatler, Ph.D.</strong><br /> Director of the Antibody Business Unit, R&D Systems</p> </p> <a href="#node-27996" title="Speak to a Scientist" class="btn btn-senary">Speak to a Scientist</a> </div></div> </div> </div> </div> <div class="col-xs-12 col-sm-6 main-container"> <div class="field field-name-field-about-video field-type-video-embed-field field-label-hidden"><div class="field-items"><div class="field-item even"> <div class="embedded-video"> <div class="player video-responsive"> <iframe class="" width="640" height="360" src="//www.youtube.com/embed/4uWGav-f_MM?width%3D640%26amp%3Bheight%3D360%26amp%3Bautoplay%3D0%26amp%3Bvq%3Dlarge%26amp%3Brel%3D0%26amp%3Bcontrols%3D1%26amp%3Bautohide%3D2%26amp%3Bshowinfo%3D1%26amp%3Bmodestbranding%3D0%26amp%3Btheme%3Ddark%26amp%3Biv_load_policy%3D1%26amp%3Bwmode%3Dopaque" frameborder="0" allowfullscreen></iframe> </div> </div> </div></div></div> </div> </div> <br> <div class="field-items field-icon-group "> <div class="row"> <div class="field-item"> <div class="col-xs-12 col-sm-2 col-md-offset-1"> <div class="icon-group text-center"> <div class="dot text-center"> <span class="num">1</span> </div> <div class="infobox_image"> <img loading="lazy" src="//resources.rndsystems.com/images/services/bts/group-work.svg" class="" alt="Consult with antibody experts" title="Consult "> </div> <p>Consult With Our Experts</p> </div> </div> </div> <div class="field-item"> <div class="col-xs-12 col-sm-2"> <div class="icon-group text-center"> <div class="dot text-center"> <span class="num">2</span> </div> <div class="infobox_image"> <img loading="lazy" src="//resources.rndsystems.com/images/services/bts/flag.svg" class="" alt="Understand your antibody goals" title="Goals"> </div> <p>Understand Your Goals</p> </div> </div> </div> <div class="field-item"> <div class="col-xs-12 col-sm-2"> <div class="icon-group text-center"> <div class="dot text-center"> <span class="num">3</span> </div> <div class="infobox_image"> <img loading="lazy" src="//resources.rndsystems.com/images/services/bts/calendar-check.svg" class="" alt="Document milestones for your antibody project " title="Document "> </div> <p>Document Milestones</p> </div> </div> </div> <div class="field-item"> <div class="col-xs-12 col-sm-2"> <div class="icon-group text-center"> <div class="dot text-center"> <span class="num">4</span> </div> <div class="infobox_image"> <img loading="lazy" src="//resources.rndsystems.com/images/services/bts/bubbles.svg" class="" alt="Communicate on antibody project" title="Communicate"> </div> <p>Initiate & Communicate</p> </div> </div> </div> <div class="field-item"> <div class="col-xs-12 col-sm-2"> <div class="icon-group text-center"> <div class="dot text-center"> <span class="num">5</span> </div> <div class="infobox_image"> <img loading="lazy" src="//resources.rndsystems.com/images/services/bts/truck.svg" class="" alt="Deliver results for your antibody project " title="Deliver "> </div> <p>Deliver Your Results</p> </div> </div> </div> </div></div> <div class="field-items field-contact-research-orginizat "> <div class="row"> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-title-wrapper"> <div class="element"> <div class="infobox_text "> <div class="three-col-headline"> <h4>Custom Antibody Conjugation Services</h4> </div> <div class="three-col-text"> <p><p>Apply our decades of custom antibody conjugation experience to your project. Our scientists will apply the appropriate protocols to your project to ensure the final conjugate meets your needs. From detection antibodies for immunoassays, to flow cytometry conjugates, we can provide small to large scale custom antibody conjugation with a fast turnaround and fully tested end material. Available conjugates include:</p> <ul> <li>Biotin</li> <li>HRP</li> <li>Alkaline Phosphatase</li> <li>Alexa Fluor<sup>®</sup> 350, 405, 488</li> <li>Alexa Fluor<sup>®</sup> 647, 700, 750</li> <li>PerCP, FITC, PE, APC</li> </ul> </p> </div> </div> </div> </div> </div> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-title-wrapper"> <div class="element"> <div class="infobox_text "> <div class="three-col-headline"> <h4>Antibody Characterization Services</h4> </div> <div class="three-col-text"> <p><p>Reproducibility is critical in your research. Identify key criterial for your antibody and receive fully characterized antibodies that meet those specifications.</p> <ul> <li>Specificity confirmation by direct ELISA</li> <li>Concentration determination</li> <li>Purity by SDS-PAGE</li> <li>Aggregation by SEC-HPLC</li> <li>Cross-reactivity testing</li> <li>Endotoxin levels by LAL</li> <li>Custom fill and finish</li> </ul> </p> </div> </div> </div> </div> </div> </div> <div class="row"> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-title-wrapper"> <div class="element"> <div class="infobox_text "> <div class="three-col-headline"> <h4>Anti-Idiotype Antibody Development</h4> </div> <div class="three-col-text"> <p><p>Anti-idiotypic antibodies play a critical role in antibody drug development. Using our established processes, we can quickly design an immunization strategy to generate custom anti-idiotypic, customized antibodies specific to your antibody drug.</p> <p>By understanding your goals, we will target antibodies for binding or blocking for your specific pharmacokinetic and immunogenicity studies.</p> </p> </div> </div> </div> </div> </div> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-title-wrapper"> <div class="element"> <div class="infobox_text "> <div class="three-col-headline"> <h4>Host Cell Protein Antibody Development</h4> </div> <div class="three-col-text"> <p><p>We can develop custom Host Cell Protein antibodies that are tailored to your cell line and specific to your process. Combine this with full assay development on our Luminex, Quantikine ELISA, or Ella platforms to provide an integral tool to your development process.</p> </p> </div> </div> </div> </div> </div> </div> <div class="row"> <div class="field-item"><div class="col-xs-12 col-sm-6 stacked-title-wrapper"> <div class="element"> <div class="infobox_text "> <div class="three-col-headline"> <h4>ProteinSimple Platforms</h4> </div> <div class="three-col-text"> <p><p>Simplify your sample analysis by utilizing our existing expertise in assay optimization on our ProteinSimple platforms. We will design an assay using our extensive antibody selection for rapid single cell or sample protein analysis. Explore our ProteinSimple platforms:</p> <ul> <li>Simple Western – analyze proteins by size from 2-440 kDa</li> <li>Simple Plex – automated immunoassays</li> <li>Single-Cell Westerns – measure cell subpopulatons</li> </ul> </p> </div> </div> </div> </div> </div> </div></div> <h2 class="field-label" >Testimonials</h2> <div class="field-items field-testimonials "> <div class="row"> <div class="field-item"><div class="testimonial col-xs-12 col-sm-4"> <div class="tstml-box"> <p><p>Conversion of our traditional monoclonal to recombinant antibody offered immortal <strong>supply of a very high quality product</strong>. We also liked the feature of the recombinant technology to be able to exchange the constant chain between different species and the ability to express the antibody as Fab fragments.</p> <p>Principal Scientist, Biotech Company</p> </p> </div> </div></div> <div class="field-item"><div class="testimonial col-xs-12 col-sm-4"> <div class="tstml-box"> <p><p>Baseline samples taken one week apart from 15 cynomolgus monkeys were obtained from a Genentech study conducted at Charles River Laboratories (Reno, NV, USA). Positive controls from three sources were used: human IgG-cyno IgG fusion molecule produced for Genentech at R&D Systems (Minneapolis, MN).</p> <p>Journal of Immunology Research<br /> Volume 2016, Article ID <a href="https://www.hindawi.com/journals/jir/2016/2618575/" target="_blank">2618575</a></p> </p> </div> </div></div> <div class="field-item"><div class="testimonial col-xs-12 col-sm-4"> <div class="tstml-box"> <p><p><a id="8205" name="8205"></a></p> </p> </div> </div></div> </div></div> <div class="field field-name-field-marketo-form field-type-et-webform field-label-hidden"><div class="field-items"><div class="field-item even"><script src="//app-ab07.marketo.com/js/forms2/js/forms2.min.js"></script> <div class="cms-webform-marketo"> <form id="mktoForm_9844"></form> <script>MktoForms2.loadForm("//app-ab07.marketo.com", "584-XSF-168", 9844);</script> </div></div></div></div> </div> </div> </section> <section id="block-block-26" class="block block-block clearfix"> <!-- Start of 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