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袠褋褋谢械写芯胁邪薪懈械 谐懈锌械褉邪薪写褉芯谐械薪械屑懈懈 | 1099512
<!doctype html> <html lang="ru"> <head> <title>袠褋褋谢械写芯胁邪薪懈械 谐懈锌械褉邪薪写褉芯谐械薪械屑懈懈 | 1099512</title> <meta name="keywords" content="笑蟹懈 啸邪薪, 笑褍薪褎褍 啸褍邪薪, 袛卸褍薪褉褍 效械薪, 楔褍褎褝薪褜 效械薪, 袘懈薪褜 袙褍, 袛褍薪屑懈薪 袦褝薪 , "/> <meta name="description" content="笑械谢褜: 袠蟹褍褔懈褌褜, 泻邪泻 泻懈褕械褔薪邪褟 屑懈泻褉芯斜懈芯褌邪 (袣袦) 褍 写械褌械泄 褋 懈写懈芯锌邪褌懈褔械褋泻懈屑 褑械薪褌褉邪谢褜薪褘屑 锌褉械卸..1099512"/> <meta name="citation_publisher" content="袥芯薪谐写芯屑 懈蟹写邪褌械谢褜褋泻邪褟 小袥" /> <meta name="citation_journal_title" content="袣谢懈薪懈褔械褋泻邪褟 锌械写懈邪褌褉懈褟: 芯褌泻褉褘褌褘泄 写芯褋褌褍锌"> <meta name="citation_title" content="袠褋褋谢械写芯胁邪薪懈械 谐懈锌械褉邪薪写褉芯谐械薪械屑懈懈 懈 褉械蟹懈褋褌械薪褌薪芯褋褌懈 泻 懈薪褋褍谢懈薪褍 褍 写械褌械泄 褋 懈写懈芯锌邪褌懈褔械褋泻懈屑 褑械薪褌褉邪谢褜薪褘屑 锌褉械卸写械胁褉械屑械薪薪褘屑 锌芯谢芯胁褘屑 褋芯蟹褉械胁邪薪懈械屑 薪邪 芯褋薪芯胁械 屑懈泻褉芯斜懈芯褌褘 泻懈褕械褔薪懈泻邪 "> <meta name="citation_author" content="笑蟹懈 啸邪薪" /> <meta name="citation_author" content="笑褍薪褎褍 啸褍邪薪" /> <meta name="citation_author" content="袛卸褍薪褉褍 效械薪" /> <meta name="citation_author" content="楔褍褎褝薪褜 效械薪" /> <meta name="citation_author" content="袘懈薪褜 袙褍" /> <meta name="citation_author" content="袛褍薪屑懈薪 袦褝薪" /> <meta name="citation_year" content=""> <meta name="citation_volume" content="9"> <meta name="citation_issue" content="5"> <meta name="citation_abstract" content="笑械谢褜: 袠蟹褍褔懈褌褜, 泻邪泻 泻懈褕械褔薪邪褟 屑懈泻褉芯斜懈芯褌邪 (袣袦) 褍 写械褌械泄 褋 懈写懈芯锌邪褌懈褔械褋泻懈屑 褑械薪褌褉邪谢褜薪褘屑 锌褉械卸写械胁褉械屑械薪薪褘屑 锌芯谢芯胁褘屑 褋芯蟹褉械胁邪薪懈械屑 (袠笑袩袩) 胁谢懈褟械褌 薪邪 谐懈锌械褉邪薪写褉芯谐械薪械屑懈褞 (袚袗) 懈 懈薪褋褍谢懈薪芯褉械蟹懈褋褌械薪褌薪芯褋褌褜 (袠袪). 袦械褌芯写褘: 袙 褝褌芯屑 懈褋褋谢械写芯胁邪薪懈懈 屑褘 薪邪斜褉邪谢懈 27 写械褌械泄 褋 袠笑袩袩 (谐褉褍锌锌邪 袠笑袩袩) 懈 23 蟹写芯褉芯胁褘褏 褉械斜械薪泻邪 (蟹写芯褉芯胁邪褟 谐褉褍锌锌邪) 懈 褋芯斜褉邪谢懈 芯斜褉邪蟹褑褘 泻褉芯胁懈 懈 泻邪谢邪 褍 褍褔邪褋褌薪懈泻芯胁. 袨斜褉邪蟹褑褘 泻褉芯胁懈 斜褘谢懈 锌褉芯胁械褉械薪褘 薪邪 谐芯褉屑芯薪褘, 胁泻谢褞褔邪褟 褎芯谢谢懈泻褍谢芯褋褌懈屑褍谢懈褉褍褞褖懈泄 谐芯褉屑芯薪, 谢褞褌械懈薪懈蟹懈褉褍褞褖懈泄 谐芯褉屑芯薪, 褝褋褌褉邪写懈芯谢, 锌褉芯谢邪泻褌懈薪 懈 褌械褋褌芯褋褌械褉芯薪. 袛械蟹芯泻褋懈褉懈斜芯薪褍泻谢械懈薪芯胁邪褟 泻懈褋谢芯褌邪 (袛袧袣) 斜褘谢邪 懈蟹胁谢械褔械薪邪 懈蟹 芯斜褉邪蟹褑芯胁 泻邪谢邪, 邪屑锌谢懈褎懈褑懈褉芯胁邪薪邪 懈 褋械泻胁械薪懈褉芯胁邪薪邪 褋 胁邪褉懈邪斜械谢褜薪芯泄 芯斜谢邪褋褌褜褞 16S 褉懈斜芯褋芯屑邪谢褜薪芯泄 袛袧袣 (16S 褉袛袧袣) (V3-V4). 袧邪泻芯薪械褑, 屑褘 邪薪薪芯褌懈褉芯胁邪谢懈 褉械蟹褍谢褜褌邪褌褘 褋械泻胁械薪懈褉芯胁邪薪懈褟, 锌芯写褋褔懈褌邪谢懈 褉邪蟹谢懈褔懈褟 胁 谐芯褉屑芯薪邪谢褜薪褘褏 锌芯泻邪蟹邪褌械谢褟褏 懈 褋芯褋褌邪胁械 GM 屑械卸写褍 写胁褍屑褟 谐褉褍锌锌邪屑懈 懈 锌褉芯邪薪邪谢懈蟹懈褉芯胁邪谢懈 泻芯褉褉械谢褟褑懈褞 褋 泻谢懈薪懈褔械褋泻懈屑懈 锌芯泻邪蟹邪褌械谢褟屑懈. 袪械蟹褍谢褜褌邪褌褘: 1. 袩芯 褋褉邪胁薪械薪懈褞 褋芯 蟹写芯褉芯胁芯泄 谐褉褍锌锌芯泄 褍褉芯胁薪懈 谐芯褉屑芯薪芯胁, 褌邪泻懈褏 泻邪泻 邪薪写褉芯褋褌械薪写懈芯薪 (袗2), 懈薪褋褍谢懈薪, 懈薪写械泻褋 褉械蟹懈褋褌械薪褌薪芯褋褌懈 泻 懈薪褋褍谢懈薪褍 懈 懈薪褋褍谢懈薪芯锌芯写芯斜薪褘泄 褎邪泻褌芯褉 褉芯褋褌邪 1 (IGF-1) 胁 谐褉褍锌锌械 ICPP 斜褘谢懈 蟹薪邪褔懈褌械谢褜薪芯 胁褘褕械 (p < 0,05); 2. 袧邪 褍褉芯胁薪械 褌懈锌邪 谐褉褍锌锌邪 ICPP 锌芯泻邪蟹邪谢邪 蟹薪邪褔懈褌械谢褜薪芯械 芯斜芯谐邪褖械薪懈械 Proteobacteria , 褔械屑 蟹写芯褉芯胁邪褟 谐褉褍锌锌邪 (4,85% 锌褉芯褌懈胁 2,92%); 3. 袧邪 褍褉芯胁薪械 褉芯写邪 芯斜懈谢懈械 Roseburia 懈 Prevotella 斜褘谢芯 蟹薪邪褔懈褌械谢褜薪芯 胁褘褕械 胁 谐褉褍锌锌械 ICPP, 褔械屑 胁 蟹写芯褉芯胁芯泄 谐褉褍锌锌械 (7,55% 锌褉芯褌懈胁 2,01%, 3,95% 锌褉芯褌懈胁 0,19%), 薪芯 Bacteroides 斜褘谢懈 褟胁薪芯 褋薪懈卸械薪褘 胁 谐褉褍锌锌械 ICPP (29,96% 锌褉芯褌懈胁 44,91%). 袟邪泻谢褞褔械薪懈械: 袠蟹屑械薪械薪懈褟 胁 袚袦 褋锌芯褋芯斜褋褌胁褍褞褌 褉邪蟹胁懈褌懈褞 袚袗 懈 袠袪, 锌芯褋谢械写薪褟褟 屑芯卸械褌 斜褘褌褜 胁邪卸薪褘屑 锌邪褌芯谐械薪械蟹芯屑 褍 写械褌械泄 褋 袠笑袩袩. 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笑褍薪褎褍 啸褍邪薪, 袛卸褍薪褉褍 效械薪, 楔褍褎褝薪褜 效械薪, 袘懈薪褜 袙褍, 袛褍薪屑懈薪 袦褝薪 </p> <p><strong>笑械谢褜:</strong> 袠蟹褍褔懈褌褜, 泻邪泻 泻懈褕械褔薪邪褟 屑懈泻褉芯斜懈芯褌邪 (袣袦) 褍 写械褌械泄 褋 懈写懈芯锌邪褌懈褔械褋泻懈屑 褑械薪褌褉邪谢褜薪褘屑 锌褉械卸写械胁褉械屑械薪薪褘屑 锌芯谢芯胁褘屑 褋芯蟹褉械胁邪薪懈械屑 (袠笑袩袩) 胁谢懈褟械褌 薪邪 谐懈锌械褉邪薪写褉芯谐械薪械屑懈褞 (袚袗) 懈 懈薪褋褍谢懈薪芯褉械蟹懈褋褌械薪褌薪芯褋褌褜 (袠袪).</p> <p><strong>袦械褌芯写褘:</strong> 袙 褝褌芯屑 懈褋褋谢械写芯胁邪薪懈懈 屑褘 薪邪斜褉邪谢懈 27 写械褌械泄 褋 袠笑袩袩 (谐褉褍锌锌邪 袠笑袩袩) 懈 23 蟹写芯褉芯胁褘褏 褉械斜械薪泻邪 (蟹写芯褉芯胁邪褟 谐褉褍锌锌邪) 懈 褋芯斜褉邪谢懈 芯斜褉邪蟹褑褘 泻褉芯胁懈 懈 泻邪谢邪 褍 褍褔邪褋褌薪懈泻芯胁. 袨斜褉邪蟹褑褘 泻褉芯胁懈 斜褘谢懈 锌褉芯胁械褉械薪褘 薪邪 谐芯褉屑芯薪褘, 胁泻谢褞褔邪褟 褎芯谢谢懈泻褍谢芯褋褌懈屑褍谢懈褉褍褞褖懈泄 谐芯褉屑芯薪, 谢褞褌械懈薪懈蟹懈褉褍褞褖懈泄 谐芯褉屑芯薪, 褝褋褌褉邪写懈芯谢, 锌褉芯谢邪泻褌懈薪 懈 褌械褋褌芯褋褌械褉芯薪. 袛械蟹芯泻褋懈褉懈斜芯薪褍泻谢械懈薪芯胁邪褟 泻懈褋谢芯褌邪 (袛袧袣) 斜褘谢邪 懈蟹胁谢械褔械薪邪 懈蟹 芯斜褉邪蟹褑芯胁 泻邪谢邪, 邪屑锌谢懈褎懈褑懈褉芯胁邪薪邪 懈 褋械泻胁械薪懈褉芯胁邪薪邪 褋 胁邪褉懈邪斜械谢褜薪芯泄 芯斜谢邪褋褌褜褞 16S 褉懈斜芯褋芯屑邪谢褜薪芯泄 袛袧袣 (16S 褉袛袧袣) (V3-V4). 袧邪泻芯薪械褑, 屑褘 邪薪薪芯褌懈褉芯胁邪谢懈 褉械蟹褍谢褜褌邪褌褘 褋械泻胁械薪懈褉芯胁邪薪懈褟, 锌芯写褋褔懈褌邪谢懈 褉邪蟹谢懈褔懈褟 胁 谐芯褉屑芯薪邪谢褜薪褘褏 锌芯泻邪蟹邪褌械谢褟褏 懈 褋芯褋褌邪胁械 GM 屑械卸写褍 写胁褍屑褟 谐褉褍锌锌邪屑懈 懈 锌褉芯邪薪邪谢懈蟹懈褉芯胁邪谢懈 泻芯褉褉械谢褟褑懈褞 褋 泻谢懈薪懈褔械褋泻懈屑懈 锌芯泻邪蟹邪褌械谢褟屑懈.</p> <p><strong>袪械蟹褍谢褜褌邪褌褘:</strong> 1. 袩芯 褋褉邪胁薪械薪懈褞 褋芯 蟹写芯褉芯胁芯泄 谐褉褍锌锌芯泄 褍褉芯胁薪懈 谐芯褉屑芯薪芯胁, 褌邪泻懈褏 泻邪泻 邪薪写褉芯褋褌械薪写懈芯薪 (袗2), 懈薪褋褍谢懈薪, 懈薪写械泻褋 褉械蟹懈褋褌械薪褌薪芯褋褌懈 泻 懈薪褋褍谢懈薪褍 懈 懈薪褋褍谢懈薪芯锌芯写芯斜薪褘泄 褎邪泻褌芯褉 褉芯褋褌邪 1 (IGF-1) 胁 谐褉褍锌锌械 ICPP 斜褘谢懈 蟹薪邪褔懈褌械谢褜薪芯 胁褘褕械 (p < 0,05); 2. 袧邪 褍褉芯胁薪械 褌懈锌邪 谐褉褍锌锌邪 ICPP 锌芯泻邪蟹邪谢邪 蟹薪邪褔懈褌械谢褜薪芯械 芯斜芯谐邪褖械薪懈械 Proteobacteria , 褔械屑 蟹写芯褉芯胁邪褟 谐褉褍锌锌邪 (4,85% 锌褉芯褌懈胁 2,92%); 3. 袧邪 褍褉芯胁薪械 褉芯写邪 芯斜懈谢懈械 Roseburia 懈 Prevotella 斜褘谢芯 蟹薪邪褔懈褌械谢褜薪芯 胁褘褕械 胁 谐褉褍锌锌械 ICPP, 褔械屑 胁 蟹写芯褉芯胁芯泄 谐褉褍锌锌械 (7,55% 锌褉芯褌懈胁 2,01%, 3,95% 锌褉芯褌懈胁 0,19%), 薪芯 Bacteroides 斜褘谢懈 褟胁薪芯 褋薪懈卸械薪褘 胁 谐褉褍锌锌械 ICPP (29,96% 锌褉芯褌懈胁 44,91%).</p> <p><strong>袟邪泻谢褞褔械薪懈械:</strong> 袠蟹屑械薪械薪懈褟 胁 袚袦 褋锌芯褋芯斜褋褌胁褍褞褌 褉邪蟹胁懈褌懈褞 袚袗 懈 袠袪, 锌芯褋谢械写薪褟褟 屑芯卸械褌 斜褘褌褜 胁邪卸薪褘屑 锌邪褌芯谐械薪械蟹芯屑 褍 写械褌械泄 褋 袠笑袩袩.</p> <div class="alert alert-info text-left"><b>袨褌泻邪蟹 芯褌 芯褌胁械褌褋褌胁械薪薪芯褋褌懈:</b> 协褌芯褌 褌械蟹懈褋 斜褘谢 锌械褉械胁械写械薪 褋 懈褋锌芯谢褜蟹芯胁邪薪懈械屑 懈薪褋褌褉褍屑械薪褌芯胁 懈褋泻褍褋褋褌胁械薪薪芯谐芯 懈薪褌械谢谢械泻褌邪 懈 械褖械 薪械 锌褉芯褕械谢 褉械褑械薪蟹懈褉芯胁邪薪懈械 懈谢懈 锌褉芯胁械褉泻褍.</div> <div class="nav social-icons"> <a class="nav-link w-auto">袩芯写械谢懈褌械褋褜 褝褌芯泄 褋褌邪褌褜械泄</a> <a title="袧邪卸屑懈褌械 蟹写械褋褜" 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