Cancer Biology | The University of Kansas Cancer Center

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their surrounding microenvironments. The Cancer Biology research program represents <a href="https://www.kucancercenter.org/research/research-areas">basic science</a> initiatives of The University of Kansas Cancer Center. Members focus on four discipline-based themes: </p> <ol> <li>Cancer metastasis and tumor microenvironment</li> <li>Cell proliferation/differentiation regulation and DNA damage/repair</li> <li>Stem cell biology and cell signaling pathways. </li> </ol> <p>Members of the Cancer Biology research program aim to understand the molecular mechanisms that define normal and neoplastic cell growth to identify and characterize cells, molecules, pathways and processes that are involved in cancer growth and progression. Their findings can serve as useful biomarkers or new cellular targets for cancer prevention and therapeutics. Members focus their efforts on the cancers that most affect people in the cancer center’s catchment area. Overall, their goal is to advance promising basic discoveries into clinical trials.<br /> <br /> The Cancer Biology research program is led by <a href="https://www.kucancercenter.org/find-a-researcher/researcher-finder-results/tomoo-iwakuma-md-phd">Tomoo Iwakuma, MD, PhD</a> (Children's Mercy Research Intitute), <a href="https://www.kucancercenter.org/find-a-researcher/researcher-finder-results/linheng-li-phd">Linheng Li, PhD</a> (Stowers Institute), and <a href="https://www.kucancercenter.org/find-a-researcher/researcher-finder-results/sufi-thomas-phd">Sufi Thomas, PhD</a> (University of Kansas Medical Center).</p></div> <div></div> </section> <section class="section-default"> <div class="three-column-cards"> <div class="container"> <div class="three-column-inner"> <div class="row"> <div class="col-md-6 col-lg-4 d-md-flex"> <a href="/news-room/news/2025/01/research-sheds-new-light-on-a-key-ovarian-cancer-biomarker" class="module-content data-gtm-featuredCallout" data-contentTitle="Research Sheds New Light on a Key Ovarian Cancer Biomarker" > <div class="module-content-copy"> <h3 class="title">Research Sheds New Light on a Key Ovarian Cancer Biomarker</h3> <div><span style="background-color: #ffffff;">Researchers have created a new structured model of the CA125 protein</span></div> <div class="arrow-next"></div> </div> </a> </div> <div class="col-md-6 col-lg-4 d-md-flex"> <a href="/news-room/blog/2025/02/a-researchers-guide-to-the-cancer-biology-program" class="module-content data-gtm-featuredCallout" data-contentTitle="A Researcher's Guide to the Cancer Biology Program" > <div class="module-content-copy"> <h3 class="title">A Researcher's Guide to the Cancer Biology Program</h3> <div><span style="color: rgba(0, 0, 7, 0.75); background-color: #ffffff;">Promising discoveries in the lab may someday lead to a better cancer treatment.</span></div> <div class="arrow-next"></div> </div> </a> </div> <div class="col-md-6 col-lg-4 d-md-flex"> <a href="/news-room/news/2021/04/turning-up-the-heat-study-to-explore-immunotherapy-in-breast-cancer" class="module-content data-gtm-featuredCallout" data-contentTitle="Turning Up the Heat: Study to Explore Immunotherapy in Breast Cancer" > <div class="module-content-copy"> <h3 class="title">Turning Up the Heat: Study to Explore Immunotherapy in Breast Cancer</h3> <div><span style="background-color: #ffffff; color: #29333d;">A $450,000, three-year grant from the U.S. Department of Defense to study breast cancer cells and better understand their ability to evade the immune system.</span></div> <div class="arrow-next"></div> </div> </a> </div> </div> </div> </div> </div> </section>  <section class="section-wrapper"> <div class="callout-text callout-text-primary"> <div class="container"> <h2 style="text-align: center;">Interested in becoming a cancer center member? </h2> <p style="text-align: center;">To apply, click <a rel="noopener noreferrer" href="https://redcap.kumc.edu/surveys/?s=FKPJNJTHDT" target="_blank">here</a>. Applications are accepted throughout the year. Contact Lisa Harlan-Williams at <a href="mailto:?subject=KU%20Cancer%20Center%20Membership">lharlan-williams@kumc.edu</a> for more information regarding membership.</p> </div> </div> </section>  <div class="section-heading text-left"> <h2 class="title title-sep">Related links</h2> </div>  <div class="explore-more"> <div class="link-box-wrapper link-box-wrapper-default"> <div class="row row-flex row-flex-wrap"> <div class="col-xs-12 col-sm-6 col-md-4"> <a href="/research/research-programs/cancer-biology" class="link-box-item disabled" >Cancer Biology</a> </div> <div class="col-xs-12 col-sm-6 col-md-4"> <a href="/research/research-programs/cancer-prevention-control" class="link-box-item" >Cancer Prevention & Control</a> </div> <div class="col-xs-12 col-sm-6 col-md-4"> <a href="/research/research-programs/drug-discovery-delivery-experimental-therapeutics" class="link-box-item" >Drug Discovery, Delivery & Experimental Therapeutics</a> </div> </div> </div> </div> </div> </div> </div> </div> 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