CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,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);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="390"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "www.science.org",cType: 'managed',cRay: '8e732f5fdd88d47e',cH: 'rzaiVyUrMrn6dWBKyKRuAeiV5ApaFMc8IF3u5.r318g-1732386150-1.2.1.1-T5XtTsSEJaViqcOEgk1qNy9AB7TzahF9.CTRdl7WijDQLyXPvwl5gC4d3G1hBSm6',cUPMDTk: "\/doi\/full\/10.1126\/science.aba8767?__cf_chl_tk=sXbLA1C1CN.kU8hk_BtsXbb92jjVKtNVuF1fC9upOV4-1732386150-1.0.1.1-AwkhU8hxcCuqEgfe_Ibe2Gc_6Yi1ocrGafTcytAkRyU",cFPWv: 'g',cITimeS: '1732386150',cTTimeMs: '1000',cMTimeMs: '390000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/doi\/full\/10.1126\/science.aba8767?__cf_chl_f_tk=sXbLA1C1CN.kU8hk_BtsXbb92jjVKtNVuF1fC9upOV4-1732386150-1.0.1.1-AwkhU8hxcCuqEgfe_Ibe2Gc_6Yi1ocrGafTcytAkRyU",md: "qRmkB2D7bhgGqIPYbeGrZYzfVNpkXOkRS58lgpvF73k-1732386150-1.2.1.1-Bk3MIod55DzOj3zfeQ4W7KxBptGoWW7ve1_dLoTnsSwojhdBRhfj2cmUI7SdaYxY9uezrGDILcSwjoOwYbycBGxTw5SdNj6HED4zlnLKBmaZVihT2BPtJiaYTf6XeCN50sOUuegyOt1cwWBWkT92z8uIir8Eb_DhWD8pM39SSEEOKC7S_Otq0DkS5ekKP5Q975tb1fK3O6XL4hTuURfj_pR4nTl.z1rsJCb7WDIP_R6ZXvp.eQCJQE0LwZphsHpgzBJrSn.Oyy7KzfmFRfdQzoMnWQBlexC3MOIoROPLNh1aQntbNbUi01rIcUhz8_ogbBqf60iBu4BymPeIR0YaxkV006mrigKgO9P9IxP.wZdh8AfQ_oBaV137zBF6nWx1LhLBWl5VSdXBZGZ6U6Z8Dz7g4ZP_McUkpQs9BAQtO4dHPBxeGnsnaD_tdn5pAzAny9iZAO.8U.nh1ek7jzYhRlx0uS7GTnXtsHmJqMiG860xupEfpZj1gTTRKkIf0RMJtT2mcjRdEvcx_dtOHateV4OoYCxyyocy_ET.RP6QVCqo04ilO_.cmLMXuMe94HHhpjIIMU_KQImnVIdit.YGRT0Rg7daQsyqTUzdUGouXEAD3MM93AdntxDb0wlfOAnBJBf7mGwXNPWoJaRySN_975CWyEohGrSH9bt3nRPyFoqs_TKooEF_ornlZTMGAvsjhw_1kfxgEyHmeGXviGMoM90P1ZUvobqqmI5W8n71FLlPthHdqCkNuQq3JQfhbd709S7wVjnQra3ZCHHHvLvmqgUT461HchzaZq8u3mOIuIlTIksumA5dfXIyndCUMurCXK2roG9_1nfesXt6UjwC_malHjcNZg9PG_yM7egfVRN6YXDB0jnQ0TATqygb.eFXBi0BHjCWvvyic4u20Ye_17A.3KGRU6EK.H.DCCyPP2AibNaMxER_MvBQNQrigQJe5SzFQ95OcPTlIZTpsZ3SHlHbAZH.VDlIFUMxeyUMozfuke0l4oSZ_V8iKZOSQYo0pO5hHc6iZel_KMUs5BZfntxu4WUq.if_CCHaHniIgY.KkfbtGDHQ6uZhIUqQOGMIUUORZvQecfsaCU_YkkPjwX8DRt9w4rUOq7RabLQwe3xaxmBxlWxQEwEUzXssK.P1DkMW4eXQD3p_tzeC9_2.xxemTa20IFR4jEDlCEFW1c7OC8.q4aPCcNOUQ1bSQ6PUQsQ6TxiqQTfcTY7t2YEAsMBxtEJCt.BOOigb4DkW201pLrz2axzzI039pe5tXK1112DtaiDPyoRbW9P63Vuwuc7tUH1RJO9Wgl3Hga0FR.tpQYVFM9_aHtMCbsD38I_ueFqyldMnxiHnIKHE5.L3wXCrxwMrrySZh3ooU2F_zYLV_ndYoh6IUX6N_6EcJerz7ZMIiHPum2djseR1uYaU9vBNMMkgxUsp9v6jZKeHDYLMwVCnoAqCvL1qodbkNcWD3R2emPP37T6JSeTBOpdpVDwrGCw76VizNUl2TAfGrOAGX1oxG8NJxK9IFAgNGwqlYaiztUkStEuz91.i9JOdXLXMQ8DoCwIvxvLm.t98tLLxZaRpIC.DmYPu94Ln2sKqJLjPIPIdryjPU3gyUvh4trplX1E7He7l4QKC1PkPNQBHAMSoqsO6GpVtI9enXIlIWxrjd_Ce6QU8vBPe.5.OvI_X2d.EnoBQE7QmF1H_trAi_ku579cLiSo9T0CZK2q4c_wvYfindQvUkexM8ljDNSfjX07NPIjgzJAyttZoJfTCU1OxbPRJI6n06deT452Wk660GtZYIs1j55ZPFnnsyuGOcxnZ4un9uMqjGaPTozgC6Q2bJAl9LiSRYtRqgTS95p3WJz4VZD17IVWn1mX1PeZ2dwO6ybxeKUvJwTQfTvfqSjD5.0TkY1ufybxFEjupf7g2WiSKeOxJS6WGmAlODjQ_wOKS_tJM9pO3MYhm4b9E48Sx6zMQPIhmCZfIhz3uISg4T3N4hO8MY1Jwbnceg7NoRufiiqqeY4j3_eRFqTjjUjCDdESJn93gicj9IhhwcXMlA.iXip6RHfaacIUqyb31AQNv_C11ScEYJmzQi93XBSTZwpb2YtyhrMVaVP2oo0JZATPJVkxQFOrdBofYmaBjS8WgUm6JTI5MjBAoktmsFpOraBeqxjtzFleB0eWZE2H4T87lR3fh57PCPsqPzKECCzm9flAvAtCR9NlOZJNGUa2Jza85FXOKh6Mieg6.EEpjIekEzwuVml6M3O.o77ipnyOv3uynJFirzu9L9hcc3kYnIBl1Vn195jSAXB7y_Zrqrb1e9PNTeqZaaN7cIvH4iXWpKyw_otx7pPQ0iOh.lYKvFC33VHFwwn3oDPx6elUhKAv85_rSSjQaAUv2nDaqSgP0DznmoaNL2CxggPtqk06eG188ruGV0swNx4vm7GfHz9MjUCyY8e5mjdgzBOYOB10FSf7cvM5sCMd8F.mhdPt7tXCczul5NlXvWj2wBxpV0NCsGHJiidmNOrnbqJ58IdDBfRVhVHW8uoOzOtJNIMqsINBhqEkpMdxJ69VLaHVlmMwik8sgo_yLDWDNTFZHI1NADIdAf6V_dadHJTXwjw7lucGdljHSIkRKqp.HN2F.e_IeCYW01QRC2Xytmsb.Act0iUrkxc5Nlwy2JAqUaavQFEM6hsn6GbNc4o6fo3w8U2IMFFUz6qMr8huKp_E7PxDZmoH6Ix7VT_HQBicwvhquirQ1FwHzo9_NsVa3.YmhQ20bbz3qWrMmj.4kIf15iP63ttayqJfaW3FyILWmVyqY6LCR1N8x5pwkpVLz3Tb7SVNvug6rHsf_aF8yTFFh814pkJA5heAK6t2Sn.W.mI9bMDnSneL.TCQ0HBT0.lDGWWuPNLT0MWXa5eztKlIgSrUZFIUMiLAWoc1J.vmn67UcpbcRYF2FlOUOQyLK.8V4snd9wVStIq39nHziGkYm9S74Hn7.F5Dfy7RY8Fgy2_CGgCS1DI.qoN3CjOgO",mdrd: "DRw2.1COjm7UNRthAgHR7ASkibq_Fx5j_ME6Tkdjr4U-1732386150-1.2.1.1-u_Bew9bKKON__vOTB2P.JHm4HUCqgfnnnxTXETYhWr40idyYSY7aHo_I_hxg.d.YnCKSkf6HpQ0dEgkSzyj93a.l8SbHdaucFEULyxianpoHB1ltfh0jFe8BK6B84u5iLgR5qvN6gTrMsB_.HctfUjq2zZwzHNMuKQMYFKy1ocgKSGd_hbMG4.E3WGkjEUoP1qXAhYTgWoHRGKAshKeFPLe3C2ktbbNnELFxO7mHRAFmJq98dTlmsJJjOGlEg.sbxps4NjRTLD40UiLDwSS2AS7MKUrGdP2_qy7dPa0mutDHZ7kj1nTvlqpN4oLMg86WIM3TPZgwSOabnuQkxD_IqBypD.dIN_uWzANGlrn0Lqw03Enh2ZBgM2YpPPZVnv.D7jBS1ivVxptmWpwasr3PgA.4WGSmxeNRhc.bWMDtjFBjfpZfKSxLsci0dB3fx274P4rwn5V_bg6crVDwbrpUVADdA2YCqzMdX7R_OoKnE2RJIgxLDUx1ZWJZT0CtXA0NI2EmpvW8V1qbZXCYG2eVlNvbdWN0at3piPmMjBAi_RGIC.8rV.25s1zVgq1irRzdCB.TKqGAKJg_DXCdeNWyLkVLqhZr87LlrIfLB0ewHjE4o4Ry5m8Vb38yFTAaNMIuSe9_qsN3smlGPyrTXer9GjnCNGoZrwpdZC.ZXh_hGsHgefzMiIr7UA5hIs_UJp3BD5H_t6JfUG0QsDMINigoYqge2NRfCzfvM8mZSVJoRV_LmjrvLxHnacJRPwEPnowCS4dODCgVgC5f_uZdFw3Tjyl2SwHXxJ64KSabWpqZZYb_35R0WNMH9NEr.HzTuYmA2dSVAf2V9e52tnIPCERGJys2IJZsiGg7q14sv5VngaNYcx9yQlbhySAiToe76JNqkiKsINmfqWiKT5VUfJX2_DqilU5jviEBuWmDVDrS2S64NeSE6HobebdKqgJ23b6llQ.5RESqUqV9I3zhIbu0kRV1Nvnqf3vUGiFvZWb._PrlvEN0S1TUINXvQjZdOU_JGYp0D0fadkta5txA34PznWisqGBKdw6sRrZy6RZQKlBLwJk16aOk1SpPO7DxD2LWVRyodL4Z91gYzjoMz82iuueTHjIrPrmkGGSsWoDAjjpSrFmCEmhJaRYo_7h5oiTVZmrO2Wu7_K9wiJlNMkvqwngoHXhuWHPwl026rHkMRjD0ztUx51e0y7DlrgC.bJr3N9SutB5q2ogweEsm1KBsDY4JD9fQi_N9cOgI40bA9Gnwu_nN7kECTWHDCKI.cKSAlWE8Bc8Bu7.6GXBa8MFTbOYT4Uc3MxskKgrVZVgnicheUwitMTGcEiU4lZKt02p5lfZbzf1T8ts0d1jhOCNc4NFLuX0ndyfEn7.EZ3WxnvUSI3EOpw1Y1MLteSuwNY3OMNoGxMhLuaJWiFRKVe4UQZ57COHnA8JsoQLcNG6deSZuXSbceWsWsJIDAvVEAARpVsZ4UPpJJw7WGxzPDnzcFmX8TTL2MVPIQ3A9bU8gvMiKcThvqgcIC7TVJCugYlf0kvU0t7vQC9LuifO_fGcXvDJMrIsmBEm9u.j6qvTmXmPejFi2fLIe4rX5OKwNK5iSZXXR4inLy9oL4H9gc7JjNbL.p9ToENE.v.k9Flx02x.cWMQzxDJcHKMuLLVLCHiVi9IQ7nR7Uph4Mk.VvILOWHYh9WNpjDs1ytFwwpAj49U3inUgZTtvLhLrfS2nTiVe86prrc0F9KtdBNvCqLiOOEa3ol5RGzM1VTwwB.844YQ1oNvXzwkMopvKJ_daJApDIW1Fh75WhGkJF5XmWOmzpeOMS5r3beMDQc1m3RdshHIgc9Uz8qTvHJQ3AzRb2t6K4abDWI0MTiwlZ0kooW7NSHaEE6rwGtWhbjiw8t6P2go5UNC0S8B.e02GKX8pacq75mOz.8puTANOlxKVqBVf9eJ3MwkLBDawBUM9fToCB2eURLrWEnYAXYRcDcl_BQ_E"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/g/orchestrate/chl_page/v1?ray=8e732f5fdd88d47e';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/doi\/full\/10.1126\/science.aba8767?__cf_chl_rt_tk=sXbLA1C1CN.kU8hk_BtsXbb92jjVKtNVuF1fC9upOV4-1732386150-1.0.1.1-AwkhU8hxcCuqEgfe_Ibe2Gc_6Yi1ocrGafTcytAkRyU" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>